CN110279647A - A kind of nti-freckle, cosmetic composition and preparation method thereof - Google Patents
A kind of nti-freckle, cosmetic composition and preparation method thereof Download PDFInfo
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- CN110279647A CN110279647A CN201910691911.6A CN201910691911A CN110279647A CN 110279647 A CN110279647 A CN 110279647A CN 201910691911 A CN201910691911 A CN 201910691911A CN 110279647 A CN110279647 A CN 110279647A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The present invention relates to cosmetic field, more specifically, the present invention provides a kind of nti-freckle, cosmetic composition and preparation method thereof.First aspect present invention provides a kind of nti-freckle, cosmetic composition, and preparing raw material includes component A, B component and component C, wherein component A includes pure water, small molecule polyol, niacinamide and methyl hydroxybenzoate;B component include monoglyceride substance, alcohol benzoic ether, Long carbon chain alcohol and Nipasol;Component C includes jellyfish extract and polypeptide.Nti-freckle provided by the invention, cosmetic composition have excellent storage stability, and are conducive to resistance of the user to adverse circumstances, reduce the damage of skin;In addition, composition provided by the invention can quickly be absorbed by Cutaneous permeation under various component collective effects, increase the elasticity of skin, be saturated skin persistently, skin is allowed to feel more gloss, the loss of skin moisture can be reduced after, it is naturally pale bright that skin is presented.
Description
Technical field
The present invention relates to cosmetic field, more specifically, the present invention provides a kind of nti-freckle, cosmetic composition and its preparation side
Method.
Background technique
With the continuous improvement of society and living standards, people also constantly promote the attention rate of personal external.It pursues
No spot, whitening and beautiful healthy skin and fine image present pursuit and yearning of the people to high-end life.Daily life
Sleep insufficiency, pressure are big in work, skin water shortage, face cleaning are not thorough, ultraviolet light etc. can cause skin obscure.It is slept in above-mentioned factor
The metabolism that deficiency of sleeping will lead to human skin becomes slowly, so that aging cutin layer be caused to thicken, skin becomes obscure;It is raw
When pressure of living is big, somatotonia state causes vessel retraction and poor circulation, equally causes face obscure;In addition, skin
Dry, cuticula water deficient, will make skin gloomy;Cosmetic foundation residual can be with the formation mixed in together such as sebum and dust
Dirt, oxidation deterioration, skin can equally become low and deep unglazed;Ultraviolet light is the primary killers of skin aging, it can allow texture
Confusion, poor blood circulation, melanin accumulation, keep skin dark yellow.
Currently, commercially available many cosmetics with nti-freckle and bright color, contain chemical synthesis additive mostly, are difficult
It is absorbed and utilized by Skin Cell, is used for a long time, does not have effect not only, can also damage skin.
Summary of the invention
In view of the above technical problems, first aspect present invention provides a kind of nti-freckle, cosmetic composition, and preparing raw material includes
Component A, B component and component C, wherein component A includes pure water, small molecule polyol, niacinamide and methyl hydroxybenzoate;B component
Including monoglyceride substance, alcohol benzoic ether, Long carbon chain alcohol and Nipasol;Component C includes jellyfish extract and more
Peptide.
As a preferred technical solution of the present invention, wherein by weight, component A includes 60~75 parts of pure water, 2
~6 parts of small molecule polyols, 2~6 parts of niacinamide and 0.1~0.4 part of methyl hydroxybenzoate;B component includes 12~20 parts of glyceric acid
Ester, 5~9 parts of alcohol benzoic ethers, 0.5~1.5 part of Long carbon chain alcohol and 0.05~0.4 part of Nipasol;Component C packet
Include 1~5 part of jellyfish extract and 0.001~0.03 part of polypeptide.
As a preferred technical solution of the present invention, wherein it is hard that monoglyceride substance is selected from glyceryl monooleate, list
Glycerol, single hydrogenated castor oil glyceride, olein, stearine, glyceryl laurate ester, polyglycerol ester
Any one or more of combination of fat acid esters, caprylic/capric triglyceride, polyglycereol-3-methyl distearate.
As a preferred technical solution of the present invention, wherein monoglyceride substance includes -3 methyl of polyglycereol
Distearate, stearine and caprylic/capric triglyceride.
As a preferred technical solution of the present invention, wherein polyglycereol-3-methyl distearate, glyceryl stearate
The weight ratio of acid esters and caprylic/capric triglyceride is 1:(0.8~1.2): (0.02~0.2).
As a preferred technical solution of the present invention, wherein the hydroxyl value of the alcohol of Long carbon chain is 200~220mgKOH/g.
As a preferred technical solution of the present invention, wherein small molecule polyol is selected from ethylene glycol, propylene glycol, fourth two
Any one or more of selection of alcohol, glycerol, erythrite, xylitol, D-glucitol, inositol.
As a preferred technical solution of the present invention, wherein polypeptide appointing in nonapeptide -1, hexapeptide -1, hexapeptide -2
One or more combinations.
The second aspect of the present invention provides a kind of cosmetics containing the nti-freckle, cosmetic composition.
Third aspect present invention provides the preparation method of a kind of nti-freckle, cosmetic composition, comprising the following steps:
(1) component A mixed dissolution is obtained into water phase components by weight;
(2) B component mixed dissolution is obtained into oil phase component by weight;
(3) it adds the aqueous phase component to the oil phase component, homogeneous, stirs;
(4) step (3) obtained material is cooled down, adds jellyfish extract and polypeptide, stirring to get.
Compared with prior art, the present invention nti-freckle provided by the invention, cosmetic composition have excellent storage stability,
And be conducive to resistance of the user to adverse circumstances, reduce the damage of skin;In addition, composition provided by the invention is at various groups
It can quickly be absorbed by Cutaneous permeation under point collective effect, increase the elasticity of skin, be saturated skin persistently, make skin photosensitive again
Pool can reduce the loss of skin moisture after, and it is naturally pale bright that skin is presented.
Specific embodiment
Unless otherwise indicated, from context cues or belong to the convention of the prior art, otherwise number all in the application
It is all based on weight with percentage, and test and characterizing method used is all synchronous with the submission date of the application.If existing
There is defining for the concrete term disclosed in technology inconsistent with any definition provided herein, then with provided herein
Subject to term definition.
It is further clear, complete that the technical characteristic work in technical solution is provided to the present invention With reference to embodiment
Description, not to the limitation of its protection scope.
Word " preferred ", " preferably ", " preferred " in the present invention etc. refer to, can provide certain in some cases
The embodiment of the present invention of a little beneficial effects.However, other embodiments may also under identical circumstances or in the case of other
It is preferred.In addition, not implying that other embodiments are unavailable to the statement of one or more preferred embodiments, it is not yet
It is intended to exclude other embodiments except the scope of the present invention.The source of unmentioned component is commercially available in the present invention.
The first aspect of the present invention provides a kind of nti-freckle, cosmetic composition, prepare raw material include component A, B component with
And component C, wherein component A includes pure water, small molecule polyol, niacinamide and methyl hydroxybenzoate;B component includes monoglyceride
Substance, alcohol benzoic ether, Long carbon chain alcohol and Nipasol;Component C includes jellyfish extract and polypeptide.
Preferably, by weight, component A includes 60~75 parts of pure water, 2~6 parts of small molecule polyols, 2~6 parts of nicotinoyl
Amine and 0.1~0.4 part of methyl hydroxybenzoate;B component includes 12~20 parts of monoglyceride substances, 5~9 parts of alcohol benzoic ethers, 0.5
The alcohol and 0.05~0.4 part of Nipasol of~1.5 parts of Long carbon chains;Component C include 1~5 part of jellyfish extract and 0.001~
0.03 part of polypeptide.
It is highly preferred that by weight, component A include 70 parts of pure water, 4.5 parts of small molecule polyols, 4 parts of niacinamide and
0.25 part of methyl hydroxybenzoate;B component include 16 parts of monoglyceride substances, 7.5 parts of alcohol benzoic ethers, 1 part of Long carbon chain alcohol and
0.25 part of Nipasol;Component C includes 3 parts of jellyfish extracts and 0.01 part of polypeptide.
Small molecule polyol
Heretofore described small molecule polyol refers to the compound containing-OH and carbon atom number less than 8.
In one embodiment, small molecule polyol is selected from ethylene glycol, propylene glycol, butanediol, glycerol, erythrite, wood
Any one or more of selection of sugar alcohol, D-glucitol, inositol;Preferably, small molecule polyol is glycerol.
Niacinamide
Niacinamide is also known as niacinamide, is the amide compound of niacin, for the crystalline powder of white;It is odorless or almost without
It is smelly, bitter;Slightly draw moist.It is readily soluble in water or ethyl alcohol, it is dissolved in glycerol;Clinically it is mainly used for preventing and treating stomatitis, glossitis,
The problems such as sick sinus syndrome, atrioventricular block.
Simultaneously niacinamide be also vitamin B3 a kind of derivative and cosmetic dermatology field it is generally acknowledged skin it is anti-ageing
It is melted into part, is increasingly concerned by people in recent years, most important effect is to mitigate and prevent skin in terms of skin anti-aging
The colour of skin that skin generates in early stage aging course is dull, turns to be yellow, famished look.
Find that niacinamide is added in system can significantly improve the nti-freckle skin lightening result of composition during the experiment, it can
Melanin can be reduced due to niacinamide to transport to keratoderma, reduced melanin and deposited in cuticula, skin is avoided to become
Black, to reach light spot effect, niacinamide has the function of anti-saccharification, and the yellow after capable of desalinating protein glycation reaches bright
The effect of skin.
Monoglyceride substance
Monoglyceride substance of the invention refers to that glycerol and other organic acids are formed by Ester.
In one embodiment, monoglyceride substance is selected from glyceryl monooleate, glycerin monostearate, single hydrogenation
Castor-oil plant oil glyceride, olein, stearine, glyceryl laurate ester, polyglyceryl fatty acid ester, caprylic/capric
Any one or more of combination of triglycerides, polyglycereol-3-methyl distearate;Preferably, glyceric acid esters object
Matter includes polyglycereol-3-methyl distearate, stearine and caprylic/capric triglyceride;Further preferably
The weight ratio on ground, polyglycereol-3-methyl distearate, stearine and caprylic/capric triglyceride is 1:
(0.8~1.2): (0.02~0.2);It is highly preferred that polyglycereol-3-methyl distearate, stearine and pungent
Acid/Triglyceride DDD weight ratio is 1:1:0.1.
The present invention is not particularly limited the purchase producer of polyglycereol-3-methyl distearate;In a kind of embodiment party
In formula, polyglycereol-3-methyl distearate is TEGO Care 450.
Monoglyceride substance is added in nti-freckle, cosmetic composition mainly for improving the dispersion of each component in composition
Property, avoid the bad phenomenons such as occurring agglomeration, layering in course of dissolution, reunite, but after the monoglyceride substance of addition,
When gained nti-freckle, cosmetic composition rub in skin, it is absorbed by the skin, when compared with atrocious weather, skin can feel more dry,
Serious person will appear chap, but when selection polyglycereol-3-methyl distearate, stearine and caprylic/capric
Triglycerides, and weight ratio is regulated to 1:(0.8~1.2): when (0.02~0.2), it can be obviously improved the phenomenon, avoided simultaneously
Coagulation, lamination during storage improve skin nti-freckle, skin lightening result, may be hard due to -3 methyl two of polyglycereol
Resin acid ester contains more hydrophilic radical, contains more cyclic structure simultaneously, in raising system to the adsorption capacity of water and
Water lock ability, while forming protective film in skin surface, reduces injury of the external environment to skin, and and stearine with
And caprylic/capric triglyceride synergistic effect improves system dispersion, homogeneous in its cyclic structure, hydrophilic radical collective effect
Effect avoids layering and reunites, and hydrophilic radical accounts for main body when caprylic/capric triglyceride is more in system, in system,
Oiliness molecule segment is unstable, is easy to adsorb during storage, reunite, to form layering, the storage for reducing composition is steady
It is qualitative.
In one embodiment, alcohol benzoic ether is selected from ethylene glycol dibenzoate, triethylene glycol dibenzoate, two
Any one or more of combination of propylene glycol dibenzoate, C12-15 alcohol benzoic ether;Preferably, alcohol benzoic ether is
C12-15 alcohol benzoic ether.
The alcohol of Long carbon chain
The alcohol of Long carbon chain in the present invention refers to containing-OH and carbon atom number is greater than 8 compound.
In one embodiment, the alcohol of Long carbon chain is in docosanol, stearyl alcohol, hexadecanol, laruyl alcohol, tetradecyl alchohol
Any one or more combinations;Preferably, the hydroxyl value of the alcohol of Long carbon chain is 200~220mgKOH/g;It is highly preferred that Long carbon chain
Alcohol be stearyl alcohol.
The moistening effect of composition can be improved in the alcohol that Long carbon chain is added in nti-freckle, cosmetic composition, but needs
The type of the alcohol of Long carbon chain makes to avoid being layered with the dispersion of raising system, homogenizing effect between 200~220mgKOH/g of its hydroxyl value
, may be larger or smaller due to hydroxyl value with reunion, it will affect the balance of the aqueous group of system, oiliness group, make storage process
It is unstable between middle group, it is easy to adsorb each other, reunite, to form layering, reduce the storage stability of composition.
Jellyfish extract
Jellyfish extract is extract by jellyfish, and main component is mucoprotein, can prevent extraneous rugged environment
Caused by skin moisture lose, quick maintenance be damaged skin, and it is plain that this is primarily due to collagen, elastin laminin, natural cartilage
Deng synergistic effect;The mucoprotein can equally restore the elasticity of sensitive skin;Jellyfish extract can increase the elasticity of skin, change
Kind blood circulation, allows skin to feel more gloss, as if it is newborn.
Jellyfish is made of 4% body tissue and 96% water, potent combination outlet capacity, and tough body tissue has
Effect promotes the synthesis of silk polyprotein;Jellyfish extract can improve the synthesis of epidermal cell polyprotein, supply the more amino of skin
The moist ingredient of acid can adjust skin barrier function by promoting angling;The strength of existing natural mineral matter, brilliant cutin
Layer improvement, and the nourishing factor of skin abundance is given, realize the softness of skin beauty.
The present invention is not specially limited the source of jellyfish extract;In a kind of mode, jellyfish extract is purchased from Guangzhou
Rising sun sail.
In one embodiment, polypeptide is selected from any one or more of combination of nonapeptide -1, hexapeptide -1, hexapeptide -2;
Preferably, polypeptide is nonapeptide -1 and hexapeptide -2;It is further preferred that the weight ratio of nonapeptide -1 and hexapeptide -2 be 1:(0.8~
1.2);It is highly preferred that the weight ratio of nonapeptide -1 and hexapeptide -2 is 1:1.
It is found that while that the components collective effects such as niacinamide, monoglyceride substance, polyalcohol are dispelled during the experiment
The effect of spot, skin lightening, but effect be not it is particularly evident, when jellyfish extract being added and when polypeptide, can significantly improve nti-freckle,
Skin lightening result may not have osmosis due to monoglyceride substance, and when jellyfish extract and polypeptide is added, it can promote
Various components is absorbed into skin, thus further increase ceramide content in cuticula and enhance skin barrier function,
Percutaneous water loss is reduced, skin brightness is improved;Inhibit the combination of а-rush melanocyte and its receptor, reduces the formation of melanin,
It under collective effect, can quickly be absorbed by Cutaneous permeation, increase the elasticity of skin, be saturated skin persistently, skin is allowed to feel more gloss,
The loss of skin moisture can be reduced after, and it is naturally pale bright that skin is presented.
In one embodiment, nti-freckle, cosmetic composition the raw material for preparing further include Phenoxyethanol and essence;It is preferred that
Ground, the weight ratio of Phenoxyethanol, essence and methyl hydroxybenzoate are (1~2): (0.8~1.2): 1;It is highly preferred that Phenoxyethanol,
The weight ratio of essence and methyl hydroxybenzoate is 1.5:1:1.
The second aspect of the present invention provides a kind of skin care item containing the nti-freckle, cosmetic composition.
In the present invention, the skin care item can be various forms well known by persons skilled in the art skin care item, include and
It is not limited to aqua, lotion, face cream, eye cream, mildy wash, facial mask, BB frost, consummate liquid, suncream, sun water, acne water, acne
Dew, face cleaning water, face cleaning dew, essential oil, shampoo, moisture retention water, toner, astringent lotion, smoothing toner.The lotion, face cream are liquid frost
Class cosmetics.The mildy wash, face cleaning water, face cleaning dew refer generally to by oil phase thing, aqueous-phase material, surfactant, moisturizer, nutrition
The liquiform product that the ingredients such as agent are constituted, including but not limited to facial cleanser, face cleaning cream, clean skin liquid.The facial mask is face beautifying health keeping product
A kind of carrier, including but not limited to mud paste type, tear-pull, gel-type, hygenic towelette type facial mask.The consummate liquid refers to comprising concentration
High nutrient, including but not limited to forms such as Essence, essence dew, essence facial mask, essence hormone injection, " Jinghuasu " essence capsule.
The suncream is to be added to obstruct or absorb the sun-screening agent of ultraviolet light to reach the makeup for preventing skin by tanned sunburn
Product.
Third aspect present invention provides the preparation method of a kind of nti-freckle, cosmetic composition, comprising the following steps:
(1) component A mixed dissolution is obtained into water phase components by weight;
(2) B component mixed dissolution is obtained into oil phase component by weight;
(3) it adds the aqueous phase component to the oil phase component, homogeneous, stirs;
(4) step (3) obtained material is cooled down, adds jellyfish extract and polypeptide, stirring to get.
Preferably, the preparation method of the nti-freckle, cosmetic composition, comprising the following steps:
(1) at room temperature, component A is mixed by weight, heating stirring dissolution, 75~85 DEG C of 20~30min of heat preservation are obtained
Water phase components;
(2) at room temperature, B component is mixed by weight, heating stirring dissolution obtains oil phase component, 75~85 DEG C spare;
(3) water phase components are added in oil phase component by way of vacuumizing, 45~55HZ, 5~30min of homogeneous, in 75
~85 DEG C of 10~30min of stirring;
(4) step (3) obtained material is cooled down, 40~45 DEG C of addition Phenoxyethanols and essence, 35~40 DEG C of addition jellyfishes
Extract and polypeptide, stirring to get, and be added polypeptide first with containing 2~5% glycerol pure water dissolve, obtain final concentration 0.005
~0.02% polypeptide solution, be put in 2~6 DEG C it is spare.
It is highly preferred that the preparation method of the nti-freckle, cosmetic composition, comprising the following steps:
(1) at room temperature, component A is mixed by weight, heating stirring dissolution, 80 DEG C of heat preservation 25min obtain water phase group
Point;
(2) at room temperature, B component is mixed by weight, heating stirring dissolution obtains oil phase component, 80 DEG C spare;
(3) water phase components are added in oil phase component, 50HZ homogeneous 20min by way of vacuumizing, are stirred in 80 DEG C
20min;
(4) step (3) obtained material is cooled down, 45 DEG C of addition Phenoxyethanols and essence, 40 DEG C of addition jellyfish extracts with
And polypeptide, stirring is to get and the polypeptide being added first is dissolved with the pure water containing 3% glycerol, and the polypeptide for obtaining final concentration 0.01% is molten
Liquid, be put in 4 DEG C it is spare.
Embodiment 1
The embodiment of the present invention 1 provides a kind of nti-freckle, cosmetic composition, and preparing raw material includes component A, B component and C
Component, component A include 70 parts of pure water, 4.5 parts of small molecule polyols, 4 parts of niacinamide and 0.25 part of methyl hydroxybenzoate;B component packet
Include 16 parts of monoglyceride substances, 7.5 parts of alcohol benzoic ethers, 1 part of Long carbon chain alcohol and 0.25 part of Nipasol;Component C packet
Include 3 parts of jellyfish extracts and 0.01 part of polypeptide;
Small molecule polyol is glycerol;
Monoglyceride substance includes polyglycereol-3-methyl distearate, stearine and octanoic acid/last of the ten Heavenly stems
Acid glycerol three ester, the polyglycereol-3-methyl distearate, stearine and caprylic/capric triglyceride
Weight ratio is 1:1:0.1;
Alcohol benzoic ether is C12-15 alcohol benzoic ether;
The alcohol of Long carbon chain is stearyl alcohol;
Polypeptide is nonapeptide -1 and hexapeptide -2, and the weight ratio of nonapeptide -1 and hexapeptide -2 is 1:1;
Nti-freckle, cosmetic composition the raw material for preparing further include Phenoxyethanol and essence, Phenoxyethanol, essence and oxybenzene first
The weight ratio of ester is 1.5:1:1;
The preparation method of the nti-freckle, cosmetic composition, comprising the following steps:
(1) at room temperature, component A is mixed by weight, heating stirring dissolution, 80 DEG C of heat preservation 25min obtain water phase group
Point;
(2) at room temperature, B component is mixed by weight, heating stirring dissolution obtains oil phase component, 80 DEG C spare;
(3) water phase components are added in oil phase component, 50HZ homogeneous 20min by way of vacuumizing, are stirred in 80 DEG C
20min;
(4) step (3) obtained material is cooled down, 45 DEG C of addition Phenoxyethanols and essence, 40 DEG C of addition jellyfish extracts with
And polypeptide, stirring is to get and the polypeptide being added first is dissolved with the pure water containing 3% glycerol, and the polypeptide for obtaining final concentration 0.01% is molten
Liquid, be put in 4 DEG C it is spare.
Embodiment 2
The embodiment of the present invention 2 provides a kind of nti-freckle, cosmetic composition, and preparing raw material includes component A, B component and C
Component, component A include 75 parts of pure water, 6 parts of small molecule polyols, 6 parts of niacinamide and 0.4 part of methyl hydroxybenzoate;B component includes 20
Part monoglyceride substance, 9 parts of alcohol benzoic ethers, 1.5 parts of Long carbon chains alcohol and 0.4 part of Nipasol;Component C includes 5 parts
Jellyfish extract and 0.03 part of polypeptide;
Small molecule polyol is glycerol;
Monoglyceride substance includes polyglycereol-3-methyl distearate, stearine and octanoic acid/last of the ten Heavenly stems
Acid glycerol three ester, the polyglycereol-3-methyl distearate, stearine and caprylic/capric triglyceride
Weight ratio is 1:1.2:0.2;
Alcohol benzoic ether is C12-15 alcohol benzoic ether;
The alcohol of Long carbon chain is stearyl alcohol;
Polypeptide is nonapeptide -1 and hexapeptide -2, and the weight ratio of nonapeptide -1 and hexapeptide -2 is 1:1.2;
Nti-freckle, cosmetic composition the raw material for preparing further include Phenoxyethanol and essence, Phenoxyethanol, essence and oxybenzene first
The weight ratio of ester is 2:1.2:1;
The preparation method of the nti-freckle, cosmetic composition, comprising the following steps:
(1) at room temperature, component A is mixed by weight, heating stirring dissolution, 85 DEG C of heat preservation 30min obtain water phase group
Point;
(2) at room temperature, B component is mixed by weight, heating stirring dissolution obtains oil phase component, 85 DEG C spare;
(3) water phase components are added in oil phase component, 52HZ homogeneous 30min by way of vacuumizing, are stirred in 85 DEG C
30min;
(4) step (3) obtained material is cooled down, 45 DEG C of addition Phenoxyethanols and essence, 40 DEG C of addition jellyfish extracts with
And polypeptide, stirring is to get and the polypeptide being added first is dissolved with the pure water containing 3% glycerol, and the polypeptide for obtaining final concentration 0.02% is molten
Liquid, be put in 6 DEG C it is spare.
Embodiment 3
The embodiment of the present invention 3 provides a kind of nti-freckle, cosmetic composition, and preparing raw material includes component A, B component and C
Component, component A include 60 parts of pure water, 2 parts of small molecule polyols, 2 parts of niacinamide and 0.1 part of methyl hydroxybenzoate;B component includes 12
Part monoglyceride substance, 5 parts of alcohol benzoic ethers, 0.5 part of Long carbon chain alcohol and 0.05 part of Nipasol;Component C includes 1 part
Jellyfish extract and 0.001 part of polypeptide;
Small molecule polyol is glycerol;
Monoglyceride substance includes polyglycereol-3-methyl distearate, stearine and octanoic acid/last of the ten Heavenly stems
Acid glycerol three ester, the polyglycereol-3-methyl distearate, stearine and caprylic/capric triglyceride
Weight ratio is 1:0.8:0.02;
Alcohol benzoic ether is C12-15 alcohol benzoic ether;
The alcohol of Long carbon chain is stearyl alcohol;
Polypeptide is nonapeptide -1 and hexapeptide -2, and the weight ratio of nonapeptide -1 and hexapeptide -2 is 1:0.8;
Nti-freckle, cosmetic composition the raw material for preparing further include Phenoxyethanol and essence, Phenoxyethanol, essence and oxybenzene first
The weight ratio of ester is 1:0.8:1;
The preparation method of the nti-freckle, cosmetic composition, comprising the following steps:
(1) at room temperature, component A is mixed by weight, heating stirring dissolution, 75 DEG C of heat preservation 20min obtain water phase group
Point;
(2) at room temperature, B component is mixed by weight, heating stirring dissolution obtains oil phase component, 75 DEG C spare;
(3) water phase components are added in oil phase component, 45HZ homogeneous 5min by way of vacuumizing, are stirred in 75 DEG C
10min;
(4) step (3) obtained material is cooled down, 40 DEG C of addition Phenoxyethanols and essence, 35 DEG C of addition jellyfish extracts with
And polypeptide, stirring is to get and the polypeptide being added first is dissolved with the pure water containing 3% glycerol, and the polypeptide for obtaining final concentration 0.005% is molten
Liquid, be put in 2 DEG C it is spare.
Embodiment 4
The embodiment of the present invention 4 provides a kind of nti-freckle, cosmetic composition, specific embodiment with embodiment 1, difference
It is in the weight of the polyglycereol-3-methyl distearate, stearine and caprylic/capric triglyceride
Than for 1:1:1.
Embodiment 5
The embodiment of the present invention 5 provides a kind of nti-freckle, cosmetic composition, specific embodiment with embodiment 1, difference
It is in the content of the polyglycereol-3-methyl distearate is 0.
Embodiment 6
The embodiment of the present invention 6 provides a kind of nti-freckle, cosmetic composition, specific embodiment with embodiment 1, difference
It is in the polyglycereol-3-methyl distearate is replaced with polyglyceryl fatty acid ester.
Embodiment 7
The embodiment of the present invention 7 provides a kind of nti-freckle, cosmetic composition, specific embodiment with embodiment 1, difference
It is in the alcohol of Long carbon chain is docosanol.
Embodiment 8
The embodiment of the present invention 8 provides a kind of nti-freckle, cosmetic composition, specific embodiment with embodiment 1, difference
It is in the alcohol of Long carbon chain is tetradecyl alchohol.
Embodiment 9
The embodiment of the present invention 9 provides a kind of nti-freckle, cosmetic composition, specific embodiment with embodiment 1, difference
It is in content of peptides 0.
Embodiment 10
The embodiment of the present invention 10 provides a kind of nti-freckle, cosmetic composition, and specific embodiment is different with embodiment 1
Place is that -1 content of nonapeptide is 0.
Embodiment 11
The embodiment of the present invention 11 provides a kind of nti-freckle, cosmetic composition, and specific embodiment is different with embodiment 1
Place is that -2 content of hexapeptide is 0.
Embodiment 12
The embodiment of the present invention 12 provides a kind of nti-freckle, cosmetic composition, and specific embodiment is different with embodiment 1
Place is that jellyfish extractive content is 0.
Performance Evaluation:
1. storage stability: 1~12 resulting composition of embodiment being placed at 15 DEG C and is placed 1 year, whether observe it has point
Layer, muddy phenomenon.
2. carrying out clinical observation 480, subject is healthy women, and the age, age bracket was evenly distributed at 35~45 years old, face
There is color spot in portion, but does not have the phenomenon that frostbite or other breakages lead to facial flushes;Then 24 groups are randomly divided into be tested as follows:
A. 12 groups of subjects are randomly selected first, 1~12 resulting composition of embodiment are applied to subject face, and smear
Uniformly, adverse circumstances are simulated, temperature is 5~10 DEG C, and strong breeze, humidity is 30~35%, and subject stops 5h in the present context,
Observing subject's facial surface, whether frostbite is rubescent, and skin care item are divided into level-one, second level, three-level to the degree of protection of skin;It has
Body standard is as shown in table 1:
B. secondly for remaining 12 groups of subjects, 1~12 resulting composition of embodiment is applied to two cheek of subject, and apply
It smears uniformly, daily to use sooner or later once, the trial employment period does not use similar whitening and spot-eliminating effect product, observes before and use one
Difference after a month utilizes the AOI tool selection test spot of IPA using the face's spot picture acquired by Photomax Pro
Point calculates macro plug-in unit using L*ab and calculates separately L* value using same blob before and after skin care item, and calculates and use forward and backward test
The change rate of value, 2 spots of ipsilateral face are averaged.Subject is after 30min cleans test position before taking pictures in constant temperature
Sit quietly 30min in constant humidity environment, and analyzed area avoids laugh line, black mole and hair as far as possible.
1 skin care item of table are to skin sparing degree evaluation standard
Rank | The rubescent number of frostbite |
Level-one | 0~3 people |
Level-one | 4~10 people |
Three-level | 11~20 people |
2 the performance test results of table
Nti-freckle provided by the invention, cosmetic composition have excellent storage stability according to the experimental results, and advantageous
In resistance of the user to adverse circumstances, the damage of skin is reduced;In addition, composition provided by the invention is common in various components
It can quickly be absorbed by Cutaneous permeation under effect, increase the elasticity of skin, be saturated skin persistently, skin is allowed to feel more gloss, after
The loss of skin moisture can be reduced, it is naturally pale bright that skin is presented.
Example above-mentioned is merely illustrative, and is used to explain the present invention some features of the method.Appended right is wanted
The range as wide as possible for being intended to require to be contemplated that is sought, and embodiments as presented herein is only according to all possible implementation
The explanation of the embodiment of the combined selection of example.Therefore, the purpose of applicant is that the attached claims are not illustrated this hair
The exemplary selectional restriction of bright feature.Some numberical ranges used also include sub- model in the claims
It encloses, the variation in these ranges should also be construed to be covered by the attached claims in the conceived case.
Claims (10)
1. a kind of nti-freckle, cosmetic composition, which is characterized in that preparing raw material includes component A, B component and component C, wherein A
Component includes pure water, small molecule polyol, niacinamide and methyl hydroxybenzoate;B component includes monoglyceride substance, alcohol benzoic acid
The alcohol and Nipasol of ester, Long carbon chain;Component C includes jellyfish extract and polypeptide.
2. nti-freckle, cosmetic composition according to claim 1, which is characterized in that by weight, component A includes 60~75
Part pure water, 2~6 parts of small molecule polyols, 2~6 parts of niacinamide and 0.1~0.4 part of methyl hydroxybenzoate;B component includes 12~20
Part monoglyceride substance, 5~9 parts of alcohol benzoic ethers, 0.5~1.5 part of Long carbon chain alcohol and 0.05~0.4 part of oxybenzene third
Ester;Component C includes 1~5 part of jellyfish extract and 0.001~0.03 part of polypeptide.
3. nti-freckle according to claim 1 or claim 2, cosmetic composition, which is characterized in that monoglyceride substance is selected from single oleic acid
Glyceride, glycerin monostearate, single hydrogenated castor oil glyceride, olein, stearine, lauric acid
Any one of ester, polyglyceryl fatty acid ester, caprylic/capric triglyceride, polyglycereol-3-methyl distearate are more
The combination of kind.
4. nti-freckle, cosmetic composition according to claim 3, which is characterized in that monoglyceride substance includes polyglycereol -3
Methyl distearate, stearine and caprylic/capric triglyceride.
5. nti-freckle, cosmetic composition according to claim 4, which is characterized in that polyglycereol-3-methyl distearate,
The weight ratio of stearine and caprylic/capric triglyceride is 1:(0.8~1.2): (0.02~0.2).
6. nti-freckle according to claim 1 or claim 2, cosmetic composition, which is characterized in that the hydroxyl value of the alcohol of Long carbon chain be 200~
220mgKOH/g。
7. nti-freckle according to claim 1 or claim 2, cosmetic composition, which is characterized in that small molecule polyol be selected from ethylene glycol,
Any one or more of selection of propylene glycol, butanediol, glycerol, erythrite, xylitol, D-glucitol, inositol.
8. nti-freckle according to claim 1 or claim 2, cosmetic composition, which is characterized in that polypeptide is selected from nonapeptide -1, hexapeptide -1, six
Any one or more of combination of peptide -2.
9. a kind of skin care item containing nti-freckle, cosmetic composition as described in any one of claim 1~8.
10. the preparation method of a kind of any one according to claim 1~8 nti-freckle, cosmetic composition, which is characterized in that packet
Include following steps:
(1) component A mixed dissolution is obtained into water phase components by weight;
(2) B component mixed dissolution is obtained into oil phase component by weight;
(3) it adds the aqueous phase component to the oil phase component, homogeneous, stirs;
(4) step (3) obtained material is cooled down, adds jellyfish extract and polypeptide, stirring to get.
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Cited By (1)
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CN115607472A (en) * | 2022-10-31 | 2023-01-17 | 上海臻臣化妆品有限公司 | Liquid foundation for dry skin and preparation method thereof |
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Cited By (1)
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CN115607472A (en) * | 2022-10-31 | 2023-01-17 | 上海臻臣化妆品有限公司 | Liquid foundation for dry skin and preparation method thereof |
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