CN110269903A - A kind of drug of novel therapeutic cancer - Google Patents
A kind of drug of novel therapeutic cancer Download PDFInfo
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- CN110269903A CN110269903A CN201810213360.8A CN201810213360A CN110269903A CN 110269903 A CN110269903 A CN 110269903A CN 201810213360 A CN201810213360 A CN 201810213360A CN 110269903 A CN110269903 A CN 110269903A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/52—Sperm; Prostate; Seminal fluid; Leydig cells of testes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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Abstract
A kind of drug of novel therapeutic cancer of the present invention.It is related to cancer treatment drugs, mechanism is to improve by human body vis medicatrix naturae to improve the immunity of the human body, cure cancer, in this way, patient body can only improve due to not having cytotoxicity, will not damage, while the drug resistance of cancer cell does not work yet.Treating cancer effect is fine.The raw material weight proportioning of soup processed of this new anticancer drug composition is: sheep spermary and sperm pipe grind the aseptic freeze-dried powder 10g-30g of slurry；Natural royal jelly and water chestnut skin freeze-dried powder 12g-36g；Appropriate natural honey；The above material mixing is made into honeyed bolus or other oral preparations that each diameter is 6mm.
Description
Technical field
The present invention relates to a kind of drugs for the treatment of cancer.
Technical background
Existing treating cancer drug is the drug to kill cancer cell as mechanism mostly, but is killing cancer cell simultaneously,
Drug toxicity can damage patient body, and due to drug cytotoxicity, cancer cell generates drug resistance, makes treating cancer effect not
It is good.
Summary of the invention
A kind of novel therapeutic cancer drug of the present invention, first is that control cancer cell does not shift, indiffusion, not multiple, second is that more
Mainly normally started with adjusting patient's digestive system, is normal to blood circulation system, is normal to metabolic system, arriving human immunity
Power and human body vis medicatrix naturae improve, and excite patient itself multipotent stem cells concentration, vigor, Metabolism of Normal in blood, reach medicine
It is normal cell that object, which controls cancer, autoimmunity and vis medicatrix naturae relay curing cancers, repairs cancer cell to itself multipotent stem cells,
Such four relay and resultant force have complementary advantages, efficiency doubles, and cure cancer, due to not having cytotoxicity, patient body can only be got well
Turn, will not damage, while the drug resistance of cancer cell does not work yet.Treating cancer effect is fine.
The raw material weight proportioning of soup processed of new anticancer drug composition is:
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 10g-30g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are 1: 0.5-1.0 ratio
Wear into slurry 12g-36g
(3) appropriate natural honey
It is made into the honeyed bolus that each diameter is 6mm.
After sheep spermary crushes, the big-and-middle small peptide containing physiological activity is resolved into vivo,
With improving the immunity of the human body characteristic, it may have anticancer property.
Various life active compounds can be improved human life vigor into the human body in sheep sperm, including improve immunity and
Vis medicatrix naturae, it is containing initial cell, and life active compound can promote to excite in various active peptide and sheep sperm in sheep spermary
Human body itself multipotent stem cells activity, while it also has anticancer activity.Natural royal jelly is distinctive raising human immunity
The physiological activator of power and vis medicatrix naturae, it may have anticancer activity.Puchiin in water chestnut skin has anticancer activity and improves people
Body immunity, vis medicatrix naturae.The above substance is all natural high active substance, nontoxic and without side-effects.
Preparation method is:
(1) sheep spermary and the aseptic freeze-dried powder preparation of sperm pipe: after the healthy and strong disease-free ram slaughter of selection, the fresh sheep of taking-up
Seminal vesicle band sperm pipe, or -18 DEG C keep in cold storage 3 months within sheep spermary band sperm pipe, by examining nontoxic no pathogenic microorganism,
It is required that more than 10g/ weight, it is stainless in 316 or 316L at 10 DEG C hereinafter, removal connective tissue, is cleaned with 0 DEG C of physiological saline
Rubbed in the special meat grinder of steel, with sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio, 316 or
1 μm of partial size or less particle pulpous state is milled in the special colloid mill of 316L stainless steel, then holding pulpous state liquid is 3 in -45 DEG C of times
Hour freezing sterilizing, then gradually temperature rises to 10 DEG C of freeze-dryings, until freeze-dried powder water content≤1.0%.It is closed at 10 DEG C or less
It is protected from light storage.
(2) prepared by the natural royal jelly of and water chestnut skin mixing slurry: selection fresh royal jelly, or -18 DEG C of pool period are no more than 30
Its Pure Royal Jeuy；Fresh water chestnut skin is selected, is cleaned 2 times by 10 DEG C of physiological saline, with water chestnut skin: 10 DEG C of physiological saline weight
Than the water chestnut skin of 1 μm of partial size or less particle being milled in the special colloid mill of 316 or 316L stainless steel for 1: 0.5-1.0 ratio
Slurry, in the sterilized stainless steel material-compound tank of 316 or 316L, with royal jelly: 1 μm or less partial size water chestnut latex weight ratio is 1: 4
Ratio, investment royal jelly and is milled to 1 μm of partial size water chestnut latex below and is uniformly mixed with 80 to 100 revs/min of revolving speeds.
(3) prepared by the natural royal jelly of and water chestnut shelling pulping freeze-dried powder: fresh or refrigeration royal jelly: being milled to 1 μm of partial size
Following water chestnut latex weight ratio is 1: 4, after being uniformly mixed, is put into freeze drier in 2 hours, and pulpous state liquid is kept
Be the sterilizing of freezing in 3 hours in -45 DEG C of times, then gradually temperature rises to 10 DEG C of freeze-dryings, dry to freeze-dried powder it is aqueous≤
2.0%.Closed storage is protected from light at 10 DEG C or less.
(4) prepared by honeyed bolus: grinding the aseptic freeze-dried powder of slurry and natural by the sheep spermary and sperm pipe of above-mentioned formulation weight ratio
Royal jelly is uniformly mixed with water chestnut skin freeze-dried powder, and the proper honey for meeting Chinese Pharmacopoeia standard is added, and the mixed powder that reconciles is uniform, bee
It is sweet to refer to how much addition honey be made subject to honeyed bolus down to mixed powder on honeyed pill making machine processed in right amount, but want accurate recording that bee is added
Sweet weight, is made the honeyed bolus of diameter 6mm, chooses the weighing of 100 honeyed bolus at random, average weight, by honeyed bolus average weight with
By required dosage, in bottle placer packing honeyed bolus to bottle or pouch.
(5) or more respectively walks preparation, provides that clean rank requirement executes by country GMP.
(6) presses pharmacy acceptable dose, the sheep spermary and sperm pipe freeze-dried powder of preparation and prepares natural royal jelly and water chestnut
The mixing of shelling pulping freeze-dried powder can prepare the oral preparations such as capsule, tablet, pulvis, granule, micropill preparation by well-established law, or on
State the enteric oral preparation of oral preparation.
Specific embodiment
Embodiment 1
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 10g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are 1: 0.5-1.0 ratio
Wear into slurry 12g
(3) appropriate natural honey
It is made into the honeyed bolus that each diameter is 6mm.
Preparation method is same as above.
Embodiment 2
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 30g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling:
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are 1: 0.5-1.0 ratio
Wear into slurry 36g
(3) appropriate natural honey
It is made into the honeyed bolus that each diameter is 6mm.
Preparation method is same as above.
Embodiment 3
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 19g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling:
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are that 1: 0.5-1.0 ratio wears into slurry 25g
(3) appropriate natural honey
It is made into the honeyed bolus that each diameter is 6mm.
Preparation method is same as above.
Embodiment 4
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 10g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling:
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are that 1: 0.5-1.0 ratio wears into slurry 36g
(3) appropriate natural honey
Each diameter is the honeyed bolus of 6mm.
Preparation method is same as above.
Embodiment 5
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 30g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling:
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are 1: 0.5-1.0 ratio
Wear into slurry 12g
(3) appropriate natural honey
It is made into the honeyed bolus that each diameter is 6mm.
Preparation method is same as above.
Pharmacodynamics verification test:
Inhibition differentiation and anti-rotation shift test to growth of tumour cell: buying model mice to qualified animal testing center,
Test group is the drug of 1-5 of the embodiment of the present invention, and each 36g/kg, three times a day, dosing interval 4 hours, control group, which is administered, was
Honey, each 36g/kg, is administered three times a day.
Test result see the table below:
Claims (4)
1. a kind of drug of new treating cancer, characterized in that its purposes of one kind is the drug for treating cancer.
2. according to a kind of drug for treating cancer described in the claims 1, characterized in that its raw material weight formed is matched
Than being:
(1) sheep spermary and sperm pipe grind 1 μm or less partial size and starch aseptic freeze-dried powder
Sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio
Wear into slurry freeze-dried powder 10g-30g
(2) natural royal jelly and the aseptic freeze-dried powder of the broken 1 μm of partial size of water chestnut shelling
Royal jelly: being milled to 1 μm of partial size or less water chestnut latex weight ratio is 1: 4 aseptic freeze-dried powder
Water chestnut skin: 10 DEG C of physiological saline weight ratios are that 1: 0.5-1.0 ratio wears into slurry 12g-36g
(3) appropriate natural honey
It is made into the honeyed bolus that each diameter is 6mm.
3. according to a kind of drug for treating cancer described in the claims 1, characterized in that preparation method is:
(1) sheep spermary and the aseptic freeze-dried powder preparation of sperm pipe: after the healthy and strong disease-free ram slaughter of selection, the fresh sheep spermary of taking-up
Band sperm pipe, or -18 DEG C keep in cold storage 3 months within sheep spermary band sperm pipe, by examining nontoxic no pathogenic microorganism, it is desirable that
It is more than 10g/ weight, special in 316 or 316L stainless steel at 10 DEG C hereinafter, removal connective tissue, is cleaned with 0 DEG C of physiological saline
It is rubbed in meat grinder processed, with sheep spermary and sperm pipe: 0 DEG C of physiological saline weight ratio is 1: 0.5-1.0 ratio, in 316 or 316L
1 μm of partial size or less particle pulpous state is milled in the special colloid mill of stainless steel, then holding pulpous state liquid is 3 hours in -45 DEG C of times
Freezing sterilizing, then gradually temperature rises to 10 DEG C of freeze-dryings, until freeze-dried powder water content≤1.0%.It closed is protected from light at 10 DEG C or less
Storage.
(2) prepared by the natural royal jelly of and water chestnut skin mixing slurry: selection fresh royal jelly, or -18 DEG C of pool period are pure no more than 30 days
Royal jelly；Fresh water chestnut skin is selected, is cleaned 2 times by 10 DEG C of physiological saline, with water chestnut skin: 10 DEG C of physiological saline weight ratios are 1:
0.5-1.0 ratio is milled to the water chestnut latex of 1 μm of partial size or less particle in the special colloid mill of 316 or 316L stainless steel,
In the sterilized stainless steel material-compound tank of 316 or 316L, with royal jelly: 1 μm or less partial size water chestnut latex weight ratio is 1: 4 ratio,
It puts into royal jelly and is milled to 1 μm of partial size water chestnut latex below and be uniformly mixed with 80 to 100 revs/min of revolving speeds.
(3) prepared by the natural royal jelly of and water chestnut shelling pulping freeze-dried powder: fresh or refrigeration royal jelly: being milled to 1 μm of partial size or less
Water chestnut latex weight ratio is 1: 4, after being uniformly mixed, is put into freeze drier in 2 hours, keeps pulpous state liquid -45
DEG C time is the sterilizing of freezing in 3 hours, then gradually temperature rises to 10 DEG C of freeze-dryings, dry to freeze-dried powder it is aqueous≤2.0%.10
DEG C or less closed be protected from light storage.
(4) prepared by honeyed bolus: starching aseptic freeze-dried powder and natural queen bee grinding by the sheep spermary and sperm pipe of above-mentioned formulation weight ratio
Slurry is uniformly mixed with water chestnut skin freeze-dried powder, and the proper honey for meeting Chinese Pharmacopoeia standard is added, and the mixed powder that reconciles is uniform, and honey is suitable
Amount, which refers to, is added how much honey can be made subject to honeyed bolus down to mixed powder on honeyed pill making machine processed, but wants accurate recording that honey weight is added
Amount, is made the honeyed bolus of diameter 6mm, chooses 100 honeyed bolus weighings at random, and average weight by honeyed bolus average weight and presses institute
Dosage is needed, in bottle placer packing honeyed bolus to bottle or pouch.
(5) or more respectively walks preparation, provides that clean rank requirement executes by country GMP.
4. a kind of drug of new treating cancer, characterized in that press pharmacy acceptable dose, the sheep spermary and sperm pipe of preparation freeze
Dry powder and prepare natural royal jelly and mixed with water chestnut shelling pulping freeze-dried powder, by well-established law can prepare capsule, tablet, pulvis,
The enteric oral preparation of the oral preparations such as granula, micropill preparation or above-mentioned oral preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810213360.8A CN110269903A (en) | 2018-03-16 | 2018-03-16 | A kind of drug of novel therapeutic cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810213360.8A CN110269903A (en) | 2018-03-16 | 2018-03-16 | A kind of drug of novel therapeutic cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110269903A true CN110269903A (en) | 2019-09-24 |
Family
ID=67958567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810213360.8A Pending CN110269903A (en) | 2018-03-16 | 2018-03-16 | A kind of drug of novel therapeutic cancer |
Country Status (1)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112587560A (en) * | 2019-09-17 | 2021-04-02 | 蔡海德 | A Chinese medicinal composition |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101297818A (en) * | 2007-04-30 | 2008-11-05 | 李偃 | Animal sperm medicinal materials and uses thereof in medicaments for curing tumor, depression and multiple diseases |
-
2018
- 2018-03-16 CN CN201810213360.8A patent/CN110269903A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101297818A (en) * | 2007-04-30 | 2008-11-05 | 李偃 | Animal sperm medicinal materials and uses thereof in medicaments for curing tumor, depression and multiple diseases |
Non-Patent Citations (1)
| Title |
|---|
| 彭涛: "饮食防癌"十要"", 《农村实用技术》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112587560A (en) * | 2019-09-17 | 2021-04-02 | 蔡海德 | A Chinese medicinal composition |
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