CN110257239A - A kind of active cooperation detection equipment of thioredoxin reductase - Google Patents

A kind of active cooperation detection equipment of thioredoxin reductase Download PDF

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Publication number
CN110257239A
CN110257239A CN201910637037.8A CN201910637037A CN110257239A CN 110257239 A CN110257239 A CN 110257239A CN 201910637037 A CN201910637037 A CN 201910637037A CN 110257239 A CN110257239 A CN 110257239A
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chamber
fixed
cavity
end wall
block
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Chinese (zh)
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胡德荣
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Pujiang Huiyi Intelligent Technology Co Ltd
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Pujiang Huiyi Intelligent Technology Co Ltd
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Priority to CN201910637037.8A priority Critical patent/CN110257239A/en
Priority to JP2019149189A priority patent/JP6807500B1/en
Publication of CN110257239A publication Critical patent/CN110257239A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M39/00Means for cleaning the apparatus or avoiding unwanted deposits of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/38Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of metabolites or enzymes in the cells

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of active cooperation detection equipment of thioredoxin reductase, including detection machine, test chamber is equipped in the detection machine, the testing agency of support experiment is equipped in the test chamber, it is equipped in the test chamber lower end wall and provides the driving mechanism of power for device operation, the driving mechanism includes driving chamber, the driving chamber lower end wall is equipped with motor, the wiper mechanism of drying carrier capable of washing is additionally provided in the detection machine, the addition mechanism of medicament needed for can adding into carrier or test sample is additionally provided in the test chamber upper end wall, the device is when needing to detect, the addition to sample or medicament can be automatically performed, the dynamic addition of manpower is not needed, reduce interference of the other factors to detection, improve the accuracy of detection, and detection start and at the end of, all cleaning, drying culture dishes, guarantee the cleaning of culture dish, compared with Few influence to detection improves the efficiency of detection by mechanical transmission.

Description

A kind of active cooperation detection equipment of thioredoxin reductase
Technical field
The present invention relates to detection field, specially a kind of active cooperation detection equipment of thioredoxin reductase.
Background technique
Thioredoxin reductase activity is detected, is whether people suffer from tumour, direct evidence, therefore, thioredoxin Reductase activity detection has important role to doctor;
At this stage, when detecting thioredoxin reductase activity, it usually needs addition various medicaments, and rely on mostly in the process Tester adds manually, therefore the factor for influencing testing result increases, and is unfavorable for the accuracy of testing result, and by grasping manually Make, detection efficiency substantially reduces.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of active cooperation detection equipment of thioredoxin reductase, gram Clothes influence the problems such as detection factors are more and detection efficiency is low, and reducing influences detection factors and improve detection efficiency.
The present invention is achieved through the following technical solutions.
A kind of active cooperation detection plant machinery structure chart of thioredoxin reductase of the invention, main includes detection Machine, the detection machine is interior to be equipped with test chamber, and the testing agency that support is tested, the test chamber lower end wall are equipped in the test chamber Interior be equipped with provides the driving mechanism of power for device operation, and the driving mechanism includes driving chamber, and the driving chamber lower end wall is set There is motor, the motor upper end is connected by power the drive shaft that upper end is located in the test chamber, the company of sliding in the drive shaft It is connected to the first sprocket wheel, driving plate and the first belt pulley, driving chamber left end wall is fixed with two pieces and supports described first respectively The support plate of sprocket wheel and first belt pulley, first sprocket wheel is interior to be equipped with electromagnetic cavity, is equipped with and is fixed in the electromagnetic cavity The first electromagnet in the electromagnetic cavity and the second electromagnet that can be slided in the electromagnetic cavity, first electromagnet with It is connected between second electromagnet by connecting spring, the driving hole of opening upwards, the driving is equipped in first belt pulley Also key connection has drive disk on axis, and the annular chamber that Open Side Down is equipped in the driving plate, is equipped with two pieces of cunnings in the annular chamber Motion block, the sliding shoe lower end are fixed with the drive rod that lower end connects the drive disk, and the drive disk is interior equipped with Open Side Down Ejection hole, lower end is equipped in the ejection hole and is located at the drive rod in the driving hole and the drive rod reset can be made Ejector spring, the driving plate lower end surface is fixed with the magnet bar that lower end can repel each other attracting with first electromagnet, described Driving plate lower end surface is further fixed on the support spring that lower end is connect with the upside support plate;
The wiper mechanism of drying carrier capable of washing is additionally provided in the detection machine, being additionally provided in the test chamber upper end wall can be to load The addition mechanism of medicament needed for adding in vivo or test sample can reduce other factors pair by the work of the wiper mechanism The interference of experiment guarantees the accuracy of experiment.
Further, the testing agency includes the supporting block of rotation connection with the test chamber lower end wall., the support The rotation chamber that Open Side Down is equipped in block, the drive shaft upper end is intracavitary positioned at the rotation and is fixed with rotating block, and described turn It is set in motion block there are two the spring groove for being connected to the rotation chamber, the spring groove is interior to be equipped with spring block and can make the spring block The adjustable spring of reset is additionally provided with the sliding eyes of two connections test chamber and the rotation chamber, institute in the supporting block It states and is equipped with the trapeze bar that one end is located in the test chamber in sliding eye, being additionally provided in the test chamber can be such that the trapeze bar returns To the ring block in the sliding eye, the ring block right end is fixed with the connecting rod that lower end is connect with the driving plate, described Supporting block upper end is fixed with drive plate, is set in the drive plate there are two rotation slot, the company of rotation between end wall before and after the rotation slot It is connected to rotation axis, it is described to be connected between the rotation trough end wall by torsionspring in rotation axis, it is fixed in the rotation axis Rotor plate is fixed with sucker on the rotor plate, is adsorbed with the culture dish as carrier on the sucker, in the drive plate also Equipped with driven chamber, it is rotatably connected to driven shaft between end wall before and after the driven chamber, driven wheel is fixed on the driven shaft, it is described Driven wheel is equipped with the follower lever contacted with the driven wheel in two sides up and down, and one end of the follower lever is located at the rotation slot It is interior, the friction pulley contacted with the follower lever is further fixed in the rotation axis, the downside follower lever right end is fixed with lower end Friction block in the test chamber, the test chamber lower end wall be additionally provided with connection free surrounding space outlet conduit, it is described go out Electromagnetic switch is equipped in waterpipe.
Further, the cleaning mechanism includes the drive cavity in the driving chamber left hand end wall, the drive cavity Lower end wall is rotatably connected to transmission shaft, and the second sprocket wheel, two second sprocket wheels and described first are fixed on the transmission shaft It is connected between sprocket wheel by chain, the left side transmission shaft upper end is fixed with first bevel gear, and the first bevel gear left end is nibbled Conjunction has second bevel gear, and the second bevel gear center is fixed with the belt that left end is connect with the left side drive cavity left end wall Axis is fixed with the second belt pulley on the belt shaft, be equipped in the drive cavity upper end wall of left side connection free surrounding space with it is described The vented cavity of test chamber is fixed with filter screen and heating tube in the vented cavity, is further fixed on support rod in the vented cavity, It is additionally provided with the rotary shaft through the support rod in the vented cavity, is fixed in the rotary shaft logical with second belt pulley The second belt pulley for crossing the connection of the first belt, is further fixed on rotating wheel and fan leaf in the rotary shaft, after the vented cavity It is equipped with closing chamber for opening forward in end wall, be additionally provided in the detection machine through the vented cavity and is connected to the closing chamber Sliding cavity is equipped with the sliding panel contacted with the rotating wheel in the sliding cavity and the sliding panel left end is located at the closing chamber It is interior, the closed plate that can be closed the vented cavity and connect with the sliding panel, the right side transmission shaft are equipped in the closing chamber Upper end is fixed with cam, and the telescopic cavity equipped with the connection drive cavity on the right side of lower end wall in the drive cavity upper end wall of right side is stretched Contract the intracavitary compressed spring for being equipped with piston and can making the piston reset, and the piston is fixed with lower end and is located at right side institute The pushing plate in drive cavity is stated, telescopic cavity left end wall is connected to the test chamber and the telescopic cavity upper end wall is equipped with outside connection The water inlet pipe in boundary space, the water inlet pipe is interior to be equipped with water pump, is additionally provided with left end and the friction in the drive cavity of right side The friction plate of block contact, the friction plate right end are fixed with fixed block, and the fixed block left end is fixed with described in left end and right side The reset spring of drive cavity left end wall connection.
Further, the addition mechanism includes pushing chamber, and described push is additionally provided with the shifting of opening to the left in chamber lower end wall Dynamic chamber, the driving chamber aft bulkhead is interior to be connected to the connecting cavity for pushing chamber, the connecting cavity lower end wall rotation equipped with upper end wall Be connected with upper end be located at it is described push intracavitary helical axis, the helical axis lower end is fixed with first belt pulley by the 4th belt pulley of two belts connection, the helical axis threaded upper ends are connected with movable plate, described to push intracavitary be equipped under two pieces Pressing plate, the upside lower platen upper end are fixed with the down-pressed pole that the movable plate is run through in upper end, the downside lower platen lower end surface Fixed there are four lower ends to be located at the lower lock block in the mobile cavity, passes through two between the movable plate and the upside lower platen Lower pressing spring connection passes through two limit spring connections, the shifting between the downside lower platen and the pushing chamber lower end wall Dynamic chamber right end wall is fixed with electromagnetic block, and the electromagnetic block left side is fixed with mobile bar, and slidably connecting in the mobile bar can Repel each other attracting movable block with the electromagnetic block, the mobile cavity lower end wall is fixed, and there are four the storages that can accommodate medicament or sample Box, the movable block is interior, and equipped with opening, end wall runs through the lifting chamber of the movable block forward and up and down, and the lifting is intracavitary to be equipped with It is lifted block, is equipped with the lifting slot for being connected to the lifting chamber in the lifting chamber left hand end wall, the lifting block left and right ends are equal It is located at the lifting plate in the lifting slot equipped with one end, the lifting slot lower end wall is fixed with what upper end was connect with the lifting plate Be lifted spring, be additionally provided with extrusion chamber in the lifting block, equipped with two pieces of magnetic boards in the extrusion chamber, two pieces of magnetic boards it Between be equipped with lower end and be located at the dropper in the mobile cavity, communication with detection chamber on the right side of the mobile cavity lower end wall, the detection machine left side Side is equipped with the L plate that can close the mobile cavity.
Further, every time from when being initially rotated to stop operating, first electromagnet is respectively positioned on first sprocket wheel On the downside of the magnet plunger, first electromagnet and second electromagnet can only have a job to generate magnetic within the same time Property.
Further, the frictional force between the friction plate and the detection machine is slightly less than the elastic force of the reset spring.
Further, the frictional force between the down-pressed pole and the movable plate is greater than the elastic force of two lifting springs With the sum of the elastic force of two limit springs.
Beneficial effects of the present invention: the apparatus structure is simple, and it is convenient to operate, which, can be automatic complete when needing to detect The addition of paired samples or medicament does not need the dynamic addition of manpower, reduces interference of the other factors to detection, improve the accurate of detection Property, and detection start and at the end of, all cleaning, drying culture dishes guarantees the cleaning of culture dish, the less influence to detection, By mechanical transmission, the efficiency of detection is improved.
Detailed description of the invention
It, below will be to embodiment or existing in order to illustrate more clearly of inventive embodiments or technical solution in the prior art Attached drawing needed in technical description is briefly described, it should be apparent that, the accompanying drawings in the following description is only to invent Some embodiments for those of ordinary skill in the art without creative efforts, can also basis These attached drawings obtain other attached drawings.
Fig. 1 is the structural schematic diagram of the embodiment of the present invention;
Fig. 2 is the main view enlarged structure schematic diagram of the driving mechanism partial cutaway of the embodiment of the present invention;
Fig. 3 is the left view enlarged structure schematic diagram of the connecting cavity complete section of the embodiment of the present invention;
Fig. 4 is the main view enlarged structure schematic diagram of the movable block complete section of the embodiment of the present invention;
Fig. 5 is the main view enlarged structure schematic diagram of the drive plate complete section of the embodiment of the present invention.
Specific embodiment
Below with reference to Fig. 1-5, the present invention is described in detail, wherein for sake of convenience, now to hereafter described orientation Provide as follows: hereafter described front-rear direction up and down is consistent with the front-rear direction up and down of Fig. 1 projection relation itself.
A kind of active cooperation detection plant machinery structure chart of thioredoxin reductase in conjunction with described in attached drawing 1-5, it is main To include detection machine 88, test chamber 51 is equipped in the detection machine 88, the detection machine of support experiment is equipped in the test chamber 51 Structure 106, interior be equipped with of 51 lower end wall of test chamber provide the driving mechanism 104 of power, the driving mechanism 104 for device operation Including driving chamber 70,70 lower end wall of driving chamber is equipped with motor 34, and 34 upper end of motor has been connected by power upper end and has been located at institute The drive shaft 35 in test chamber 51 is stated, the first sprocket wheel 36, driving plate 69 and the first skin are slidably connected in the drive shaft 35 Belt wheel 80, the 70 left end wall of driving chamber are fixed with two pieces and support first sprocket wheel 36 and first belt pulley 80 respectively Support plate 33, first sprocket wheel 33 is interior to be equipped with electromagnetic cavity 58, is equipped with and is fixed in the electromagnetic cavity 58 in the electromagnetic cavity 58 The first electromagnet 62 and the second electromagnet 59 that can be slided in the electromagnetic cavity 58, first electromagnet 62 and second It is connected between electromagnet 59 by connecting spring 60, the driving hole 63 of opening upwards is equipped in first belt pulley 80, it is described Also key connection has drive disk 84 in drive shaft 35, is equipped with the annular chamber 82 that Open Side Down, the annular chamber in the driving plate 69 Two pieces of sliding shoes 83 are equipped in 82,83 lower end of sliding shoe is fixed with the drive rod 85 that lower end connects the drive disk 84, institute It states and is equipped with the ejection hole 66 that Open Side Down in drive disk 84, be equipped with lower end in the ejection hole 66 and be located in the driving hole 63 Drive rod 64 and ejector spring 65 that the drive rod 64 can be made to reset, 69 lower end surface of driving plate is fixed with lower end can The magnet bar 67 for repelling each other attracting with first electromagnet 62,69 lower end surface of driving plate are further fixed on described in lower end and upside The support spring 68 that support plate 33 connects is additionally provided with the wiper mechanism 105 of drying carrier capable of washing in the detection machine 88, described The addition mechanism 107 of medicament needed for can adding into carrier or test sample is additionally provided in 51 upper end wall of test chamber, by described The work of wiper mechanism can reduce interference of the other factors to experiment, guarantee the accuracy of experiment.
Valuably, the testing agency 106 includes the supporting block of rotation connection with 51 lower end wall of test chamber.71, institute It states and is equipped with the rotation chamber 61 that Open Side Down in supporting block 71,35 upper end of drive shaft is located in the rotation chamber 61 and is fixed with Rotating block 78 is set in the rotating block 78 there are two the spring groove 75 for being connected to the rotation chamber 61, is equipped in the spring groove 75 Spring block 74 and the adjustable spring 77 that the spring block 74 can be made to reset are additionally provided with described in two connections in the supporting block 71 The sliding eye 79 of test chamber 51 and the rotation chamber 61, described interior one end that is equipped with of sliding eye 79 are located in the test chamber 51 Trapeze bar 73 is additionally provided with the ring block 72 that the trapeze bar 73 can be made to return in the sliding eye 79, institute in the test chamber 51 It states 72 right end of ring block and is fixed with the connecting rod 81 that lower end is connect with the driving plate 69,71 upper end of the supporting block is fixed with biography Moving plate 76 is set in the drive plate 76 there are two rotation slot 30, is rotatably connected to rotation axis between the 30 front and back end wall of rotation slot 37, it is described to be connected between 30 end wall of rotation axis 37 and the rotation slot by torsionspring 97, it is fixed in the rotation axis 37 Rotor plate 32 is fixed with sucker 38 on the rotor plate 32, the culture dish 31 as carrier is adsorbed on the sucker 38, described It is additionally provided with driven chamber 101 in drive plate 76, is rotatably connected to driven shaft 102 between the driven 101 front and back end wall of chamber, it is described driven Driven wheel 103 is fixed on axis 102, about 103 two sides of driven wheel are equipped with the follower lever contacted with the driven wheel 103 99, one end of the follower lever 99 is located in the rotation slot 30, is further fixed in the rotation axis 37 and the follower lever 99 The friction pulley 98 of contact, downside 99 right end of follower lever are fixed with the friction block 100 that lower end is located in the test chamber 51, institute The outlet conduit 39 that 51 lower end wall of test chamber is additionally provided with connection free surrounding space is stated, is equipped with electromagnetic switch in the outlet conduit 39 108。
Valuably, the cleaning mechanism 105 includes the drive cavity 25 in 70 left hand end wall of driving chamber, the biography Dynamic 25 lower end wall of chamber is rotatably connected to transmission shaft 27, and the second sprocket wheel 26, two second chains are fixed on the transmission shaft 27 It is connected between wheel 26 and first sprocket wheel 36 by chain 28, left side 27 upper end of transmission shaft is fixed with first bevel gear 24,24 left end of first bevel gear is engaged with second bevel gear 23, and 23 center of second bevel gear is fixed with left end and a left side The belt shaft 21 of the connection of 25 left end wall of drive cavity described in side, is fixed with the second belt pulley 22 on the belt shaft 21, described in left side It is equipped with the vented cavity 18 of connection free surrounding space and the test chamber 51 in 25 upper end wall of drive cavity, is fixed in the vented cavity 18 Filter screen 11 and heating tube 20 are further fixed on support rod 17 in the vented cavity 18, are additionally provided with and run through in the vented cavity 18 The rotary shaft 16 of the support rod 17 is fixed in the rotary shaft 16 and passes through the first belt 29 with second belt pulley 22 and connect The second belt pulley 14 connect is further fixed on rotating wheel 19 and fan leaf 15,18 rear end of vented cavity in the rotary shaft 16 It is equipped with closing chamber 12 for opening forward in wall, is additionally provided in the detection machine 88 through the vented cavity 18 and the connection closing The sliding cavity 3 of chamber 12, the sliding cavity 3 is interior to be equipped with the sliding panel 10 contacted with the rotating wheel 19 and 10 left end of the sliding panel The vented cavity 18 can be closed and connect with the sliding panel 10 by being equipped in the closing chamber 12, in the closing chamber 12 Closed plate 13, right side 27 upper end of transmission shaft are fixed with cam 41, are equipped with lower end wall in 25 upper end wall of drive cavity of right side Right side is connected to the telescopic cavity 47 of the drive cavity 25, the pressure for being equipped with piston 46 in telescopic cavity 46 and the piston 46 being made to reset Contracting spring 45,46 lower end of piston are fixed with the pushing plate 40 that lower end is located in the drive cavity 25 of right side, the telescopic cavity 47 left end walls are connected to the test chamber 51 and 47 upper end wall of the telescopic cavity is equipped with the water inlet pipe 48 of connection free surrounding space, described It is equipped with water pump 49 in water inlet pipe 48, is additionally provided with the friction that left end is contacted with the friction block 100 in the drive cavity 25 of right side Plate 42,42 right end of friction plate are fixed with fixed block 44, and 44 left end of fixed block is fixed with left end and the right side transmission The reset spring 43 of 25 left end wall of chamber connection.
Valuably, the addition mechanism 107 includes pushing chamber 4, is additionally provided with and is open to the left in pushing 4 lower end wall of chamber Mobile cavity 109,70 aft bulkhead of driving chamber is interior to be connected to the connecting cavity 89 for pushing chamber 4, the connecting cavity equipped with upper end wall 89 lower end walls are rotatably connected to the helical axis 53 that upper end is located in the pushing chamber 4, and 53 lower end of helical axis is fixed with and institute It states the first belt pulley 80 and passes through the 4th belt pulley 87 that the second belt 86 connects, 53 threaded upper ends of helical axis are connected with movement Plate 2, the pushing chamber 4 is interior to be equipped with two pieces of lower platens 6, and upside 6 upper end of lower platen is fixed with upper end through the movable plate 2 Down-pressed pole 56, downside 6 lower end surface of lower platen is fixed to be located at the lower lock block 7 in the mobile cavity 109, institute there are four lower end It states and is connected between movable plate 2 and the upside lower platen 6 by two lower pressing springs 5, the downside lower platen 6 and the pushing It is connected between 2 lower end wall of chamber by two limit springs 57, the 109 right end wall of mobile cavity is fixed with electromagnetic block 50, the electricity 50 left side of magnetic patch is fixed with mobile bar 8, and the attracting shifting that can repel each other with the electromagnetic block 50 is slidably connected in the mobile bar 8 Motion block 55,109 lower end wall of mobile cavity is fixed there are four the storage box 9 that can accommodate medicament or sample, in the movable block 55 Equipped with opening, end wall runs through the lifting chamber 90 of the movable block 55 forward and up and down, and lifting block 54 is equipped in the lifting chamber 90, It is equipped with the lifting slot 92 for being connected to the lifting chamber 90 in lifting 90 left hand end wall of chamber, 54 left and right ends of the lifting block are equal It is located at the lifting plate 93 in the lifting slot 92 equipped with one end, 93 lower end wall of lifting slot is fixed with upper end and the lifting plate The lifting springs 91 of 93 connections, are additionally provided with extrusion chamber 95 in the lifting block 54, equipped with two pieces of magnetic boards in the extrusion chamber 95 94, it is equipped with lower end between two pieces of magnetic boards 94 and is located at the dropper 96 in the mobile cavity 109,109 lower end of mobile cavity Communication with detection chamber 51 on the right side of wall is equipped with the L plate 1 that can close the mobile cavity 109 on the left of the detection machine 88.
Valuably, first sprocket wheel 36 is every time from when being initially rotated to stop operating, the equal position of first electromagnet 62 In 67 downside of magnet plunger, first electromagnet 62 can only have a work with second electromagnet 59 within the same time Make to generate magnetic.
Valuably, the frictional force between the friction plate 42 and the detection machine 88 is slightly less than the bullet of the reset spring 43 Power.
Valuably, the frictional force between the down-pressed pole 56 and the movable plate 2 is greater than the bullet of two lifting springs 5 The sum of the elastic force of power and two limit springs 57.
The sequence of the mechanical action of whole device:
1: physiological saline, two kinds of medicaments and sample to be tested, the first electromagnet 62 are added into four storage boxes 9 for mobile L plate 1 It does not work, the second electromagnet 59 work, the at this time work of motor 34 rotates the first sprocket wheel 36, drives two by the transmission of chain 28 A second sprocket wheel 26 rotates, so that transmission shaft 27 is driven to rotate, so that first bevel gear 24 and cam 41 is driven to rotate, and the first cone The rotation of gear 24 drives first bevel gear 23 to rotate, so that belt shaft 21 is driven to rotate, so that the second belt pulley 22 is rotated, from And the first belt pulley 14 is rotated, so that rotary shaft 16 is rotated, so that fan leaf 15 and rotating wheel 19 are rotated, rotating wheel 19 rotations drive sliding panel 10 to move backward, so that driving closed plate 13 to move backward opens vented cavity 18, heating tube 20 works, To make to blow to the wind hot wind in test chamber 51, so that the culture dish 31 in dry left side, cam 41 rotate, thus in compression bullet Under the cooperation of spring 45, the side-to-side movement of pushing plate 40 is realized, pushing plate 40, which moves downward, drives friction plate 42 to move downward, thus Move downward friction block 100, to make right side follower lever 99 move downward, to make right side friction pulley 98 and driven wheel 103 Rotation, to make left side follower lever 99 move right, to make left side friction pulley 98 rotate, to make 37 turns of two rotation axis It is dynamic, so that rotor plate 32 be made to rotate, so that two culture dishes 31 be made to distinguish face vented cavity 18 and telescopic cavity 47, open water pump 49 It fills the water into telescopic cavity 47, is sprayed water by piston 46 into test chamber 51, to clean right side culture dish 31;
2: the second electromagnet 59 of control does not work, and the first electromagnet 62 works with magnet plunger 67, thus make the first electromagnet 62 with Magnet plunger 67 repels each other, to make magnet plunger 67 rise, to make driving plate 69 and connecting rod 81 rise, to make on ring block 72 It rises, thus enter spring block 74 in sliding eye 79, at this point, drive shaft 35 drives rotating block 78 and supporting block 71 to rotate, thus Band nutating disk 76 rotates, to make two 41 location swaps of culture dish in left and right, then controls the first electromagnet 62 and magnet plunger 67 Stop working, control the second electromagnet 59 work, thus dry right side culture dish 41, cleaning left side culture dish 41, when drying or It after having cleaned culture dish 41, then controls the second electromagnet 59 and does not work, the first electromagnet 62 works with magnet plunger 67, replaces again Then culture dish 41 position in the left and right sides controls the first electromagnet 62 and stops working with magnet plunger 67, control the second electromagnet 59 Work, water pump 49 no longer works at this time, and drying left side culture dish 41, after the completion of drying, the work of drive shaft 35 is driven by transmission Rotating wheel 19 rotates, so that sliding panel 10 and the reset of closed plate 13 are controlled, enclosed ventilation chamber 18, opening electromagnetic switch 108, Close electromagnetic switch 108 after the water in test chamber 51 is discharged, finally control the second electromagnet 59 and do not work, the first electromagnet 62 with Magnet plunger 67 stops working, control the second electromagnet 59 work, and the rotation band nutating disk 76 of drive shaft 35 rotates, to make two The front and back distribution in test chamber 51 of culture dish 41, friction block 100 is separated with friction lever 42 at this time, and torsionspring 97 resets, thus Reset frictional force 98, so that rotor plate 32 be made to reset;
3: control the first electromagnet 62 work with magnet plunger 67 it is attracting, thus make magnet plunger 67 decline, to make under driving plate 69 Drop, so that drive disk 84 be made to decline, so that drive rod 64 be made to lower into driving hole 63, so that drive plate 84 be made to drive the One belt pulley 80 rotation, so that the rotation of the 4th belt pulley 87 is driven by the transmission of the second belt 86, to drive helical axis 53 Rotation, to control the lifting of movable plate 2;
4: movable plate 2 declines, and drives two pieces of lower platens 6 to decline first, thus make lower lock block 7 that elevator 54 be driven to decline, thus Enter 96 lower end of dropper in storage box 9, be attracted or repelled by controlling two pieces of magnetic boards 94, is received to control dropper 96 and draw Reagent or sample in case 9 are being moved by the magnetic size between electromagnetic block 50 and movable block 55 to control movable block 55 Position in lever 8, each dropper 96 are gone up and down once on the upside of storage box 9, and dropper 96 can move right side to the end, under Under the lifting of compression leg 52, dropper 96 can be gone up and down again, enter 96 lower end of dropper in test chamber 51, thus two blocks of electricity of secondary control again Magnetic sheet 94, thus by the reagent or sample instillation culture dish in dropper 96;
5: by control drive plate 76 rotation, thus enable dropper 96 make two culture dishes 41 obtain identical medicament or Sample opens heating tube 20, gives detection environment, provides the temperature of needs, after medicament and sample has been added in culture dish 41, etc. After a period of time, observation experiment phenomenon obtains testing result, then controls the work of wiper mechanism 105 cleaning, drying two again Culture dish.
The above embodiments merely illustrate the technical concept and features of the present invention, and its object is to allow be familiar with this field technology Personage can understand the content of present invention and be implemented, and it is not intended to limit the scope of the present invention.It is all according to the present invention Equivalent change or modification made by Spirit Essence, should be covered by the scope of protection of the present invention.

Claims (7)

1. a kind of active cooperation detection plant machinery structure chart of thioredoxin reductase mainly includes detection machine, feature It is: is equipped with test chamber in the detection machine, the testing agency of support experiment, the test chamber lower end are equipped in the test chamber It is equipped in wall and provides the driving mechanism of power for device operation, the driving mechanism includes driving chamber, the driving chamber lower end wall Equipped with motor, the motor upper end is connected by power the drive shaft that upper end is located in the test chamber, slides in the drive shaft It is connected with the first sprocket wheel, driving plate and the first belt pulley, driving chamber left end wall is fixed with two pieces and supports described respectively The support plate of one sprocket wheel and first belt pulley, first sprocket wheel is interior to be equipped with electromagnetic cavity, is equipped with and fixes in the electromagnetic cavity The first electromagnet in the electromagnetic cavity and the second electromagnet that can be slided in the electromagnetic cavity, first electromagnet It is connect between the second electromagnet by connecting spring, the driving hole of opening upwards, the drive is equipped in first belt pulley Also key connection has drive disk on moving axis, and the annular chamber that Open Side Down is equipped in the driving plate, is equipped with two pieces in the annular chamber Sliding shoe, the sliding shoe lower end are fixed with the drive rod that lower end connects the drive disk, be equipped in the drive disk opening to Under ejection hole, lower end is equipped in the ejection hole and is located at the drive rod in the driving hole and the drive rod can be made to answer The ejector spring of position, the driving plate lower end surface is fixed with the magnet bar that lower end can repel each other attracting with first electromagnet, institute It states driving plate lower end surface and is further fixed on the support spring that lower end is connect with the upside support plate;
The wiper mechanism of drying carrier capable of washing is additionally provided in the detection machine, being additionally provided in the test chamber upper end wall can be to load The addition mechanism of medicament needed for adding in vivo or test sample can reduce other factors pair by the work of the wiper mechanism The interference of experiment guarantees the accuracy of experiment.
2. the active cooperation detection equipment of a kind of thioredoxin reductase according to claim 1, it is characterised in that: The testing agency includes the supporting block of rotation connection with the test chamber lower end wall, is equipped with what Open Side Down in the supporting block Rotate chamber, it is intracavitary and be fixed with rotating block that the drive shaft upper end is located at the rotation, sets that there are two connections in the rotating block The spring groove of the rotation chamber, the interior adjustable spring for being equipped with spring block and the spring block reset being made of the spring groove, institute The sliding eye for being additionally provided with two connections test chamber and the rotation chamber in supporting block is stated, is equipped with one end in the sliding eye Trapeze bar in the test chamber is additionally provided with the ring that the trapeze bar can be made to return in the sliding eye in the test chamber Shape block, the ring block right end are fixed with the connecting rod that lower end is connect with the driving plate, and supporting block upper end is fixed with biography Moving plate is set in the drive plate there are two rotation slot, is rotatably connected to rotation axis between end wall before and after the rotation slot, described to turn It is connected between moving axis and the rotation trough end wall by torsionspring, is fixed with rotor plate in the rotation axis, on the rotor plate It is fixed with sucker, the culture dish as carrier is adsorbed on the sucker, driven chamber is additionally provided in the drive plate, it is described driven It is rotatably connected to driven shaft between end wall before and after chamber, driven wheel is fixed on the driven shaft, the driven wheel is all provided with two sides up and down There is the follower lever contacted with the driven wheel, one end of the follower lever is located in the rotation slot, also solid in the rotation axis Surely there is the friction pulley contacted with the follower lever, the downside follower lever right end is fixed with lower end and is located at rubbing in the test chamber Cleaning block, the test chamber lower end wall are additionally provided with the outlet conduit of connection free surrounding space, are equipped with electromagnetic switch in the outlet conduit.
3. the active cooperation detection equipment of a kind of thioredoxin reductase according to claim 1, it is characterised in that: The cleaning mechanism includes the drive cavity in the driving chamber left hand end wall, and the drive cavity lower end wall is rotatably connected to biography Moving axis is fixed with the second sprocket wheel on the transmission shaft, passes through chain between two second sprocket wheels and first sprocket wheel and connects It connects, the left side transmission shaft upper end is fixed with first bevel gear, and the first bevel gear left end is engaged with second bevel gear, described Second bevel gear center is fixed with the belt shaft that left end is connect with the left side drive cavity left end wall, is fixed on the belt shaft Second belt pulley, the interior vented cavity for being equipped with connection free surrounding space and the test chamber of the left side drive cavity upper end wall are described logical Wind is intracavitary to be fixed with filter screen and heating tube, and support rod is further fixed in the vented cavity, is additionally provided with and passes through in the vented cavity The rotary shaft of the support rod is worn, second connect with second belt pulley by the first belt is fixed in the rotary shaft Belt pulley is further fixed on rotating wheel and fan leaf in the rotary shaft, is equipped in the vented cavity aft bulkhead for opening forward Closing chamber, is additionally provided with the sliding cavity through the vented cavity and the connection closing chamber in the detection machine, in the sliding cavity It is located in the closing chamber equipped with the sliding panel and the sliding panel left end contacted with the rotating wheel, is equipped in the closing chamber The closed plate that the vented cavity can be closed and connect with the sliding panel, the right side transmission shaft upper end are fixed with cam, right side Equipped with the telescopic cavity for being connected to the drive cavity on the right side of lower end wall in the drive cavity upper end wall, piston is equipped in telescopic cavity and can Making the compressed spring of the piston reset, the piston is fixed with the pushing plate that lower end is located in the drive cavity of right side, Telescopic cavity left end wall is connected to the test chamber and the telescopic cavity upper end wall is equipped with the water inlet pipe of connection free surrounding space, institute It states and is equipped with water pump in water inlet pipe, be additionally provided with the friction plate that left end is contacted with the friction block in the drive cavity of right side, it is described Friction plate right end is fixed with fixed block, and the fixed block left end is fixed with left end and answers with what the right side drive cavity left end wall was connect Position spring.
4. the active cooperation detection equipment of a kind of thioredoxin reductase according to claim 1, it is characterised in that: The addition mechanism includes pushing chamber, and described push is additionally provided with the mobile cavity of opening to the left in chamber lower end wall, after the driving chamber It is connected to the connecting cavity for pushing chamber equipped with upper end wall in end wall, the connecting cavity lower end wall is rotatably connected to upper end positioned at described Intracavitary helical axis is pushed, the helical axis lower end is fixed with the 4th skin connecting with first belt pulley by the second belt Belt wheel, the helical axis threaded upper ends are connected with movable plate, and the pushing is intracavitary to be equipped with two pieces of lower platens, the upside lower platen Upper end is fixed with the down-pressed pole that the movable plate is run through in upper end, and the downside lower platen lower end surface is fixed to be located at institute there are four lower end The lower lock block in mobile cavity is stated, passes through two lower pressing spring connections, downside institute between the movable plate and the upside lower platen It states by two limit spring connections between lower platen and the pushing chamber lower end wall, the mobile cavity right end wall is fixed with electromagnetism Block, the electromagnetic block left side are fixed with mobile bar, slidably connected in the mobile bar can repel each other with the electromagnetic block it is attracting Movable block, the mobile cavity lower end wall is fixed there are four the storage box that can accommodate medicament or sample, is equipped in the movable block End wall runs through the lifting chamber of the movable block to opening forward and up and down, and the lifting is intracavitary to be equipped with lifting block, and the lifting chamber is left The lifting slot for being connected to the lifting chamber is equipped in right end wall, the lifting block left and right ends are equipped with one end and are located at the lifting Lifting plate in slot, the lifting slot lower end wall are fixed with the lifting spring that upper end is connect with the lifting plate, the lifting block It is inside additionally provided with extrusion chamber, two pieces of magnetic boards are equipped in the extrusion chamber, lower end is equipped between two pieces of magnetic boards positioned at described Dropper in mobile cavity, mobile cavity lower end wall right side communication with detection chamber, the detection machine left side, which is equipped with, can close the shifting The L plate of dynamic chamber.
5. the active cooperation detection equipment of a kind of thioredoxin reductase according to claim 1, it is characterised in that: First sprocket wheel is every time from when being initially rotated to stop operating, and first electromagnet is respectively positioned on the downside of the magnet plunger, institute Stating the first electromagnet and second electromagnet can only have a job to generate magnetism within the same time.
6. according to claim 1 or a kind of active cooperation detection equipment of thioredoxin reductase, feature described in 3 exist In: the frictional force between the friction plate and the detection machine is slightly less than the elastic force of the reset spring.
7. a kind of active cooperation detection equipment of thioredoxin reductase according to claim 4, it is characterised in that: Frictional force between the down-pressed pole and the movable plate is greater than the elastic force and two limit bullets of two lifting springs The sum of elastic force of spring.
CN201910637037.8A 2019-07-15 2019-07-15 A kind of active cooperation detection equipment of thioredoxin reductase Pending CN110257239A (en)

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CN201910637037.8A CN110257239A (en) 2019-07-15 2019-07-15 A kind of active cooperation detection equipment of thioredoxin reductase
JP2019149189A JP6807500B1 (en) 2019-07-15 2019-08-15 Cooperative measurement facility for thioredoxin reductase activity

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Application publication date: 20190920