CN110251798A - A kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease - Google Patents
A kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease Download PDFInfo
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- 208000024827 Alzheimer disease Diseases 0.000 title claims abstract description 21
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
- A61M2021/0027—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
- A61M2021/0044—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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Abstract
The present invention relates to a kind of wear-type acousto-optic therapeutic equipments for Alzheimer disease, comprising: arc shell, radiator grille, round earmuff, light source, sound source, signal amplification drive module, control module and power supply；Wherein, light source is forward-mounted in cover, it is placed in front of arc shell, sound source is mounted in round earmuff, it is placed in arc shell two sides, light source and sound source are connected with signal amplification drive module, and signal amplification drive module, control module and power supply are sequentially connected and are mounted on rear side of arc shell, and power supply is responsible for the power supply of other modules and has on-off action.The therapeutic equipment is utilized with the sound and light signal of frequency through audiovisual nerve collective effect in brain, the EEG signals of specific frequency is generated, for treating Alzheimer disease.Sound and light signal parameter is adjustable over the course for the treatment of, to meet the Treatment need of different patients.
Description
Technical field
The invention belongs to technical field of medical equipment, related with wearing Medical Devices, especially a kind of to be used for alzheimer '
The wear-type acousto-optic therapeutic equipment for disease of writing from memory.It is mainly used in clinical treatment field.
Background technique
Alzheimer disease is also referred to as senile dementia, belongs to nervous system class disease, research shows that in such patient's brain
β-amyloid proteins content it is higher than normal person, inflammatory reaction is more, synaptic function reduce.Neuron is serious because of loss is denaturalized,
It is clinically mainly shown as the symptoms such as decrease of memory, personality and behavior change, cognitive ability obstacle, has seriously affected patient's
Life.It is directed to Alzheimer disease at present, main treatment method is to take control with the psychotic symptoms occurred or mention
Height improves the drug of cognition, such as Memantine, easy times of Shen.This kind of drug is mainly to act on the NMDA(N- for influencing neuronal circuit
Methyl-D-aspartic acid receptor) receptor, restores point after excitatory synapse, improves telecommunications between neuron
The signal-to-noise ratio of number transmitting, pathological symptom spiritual for anxiety, intense, depressed etc. have clear improvement.But due to pathogenic factor
Diversity, drug therapy can not thoroughly cure Alzheimer disease at present, but also have the side effect after taking, such as abdomen
It rushes down, muscle cramp, out of strength and headache etc..
In addition to drug treatment, there are also the physical therapy modalities of auxiliary for Alzheimer disease.Current main physics is controlled
Treating instrument is exactly Brain Circulation Function Rapentic Instrument, which is the biological electromagnetic field principle according to human brain, passes through computer technology
Specific electric field is synthesized and generated, electro photoluminescence is carried out to human brain, promotes cerebral blood circulation, adjusts the disorder of nervous system, mention
Tall and big brain cognitive function.This treatment means have certain auxiliary therapeutic action to Alzheimer disease, are more suitable for early prevention
With alleviate illness, but there is no positive effect for patients with Alzheimer disease more than moderate.
In recent years studies at home and abroad show that, brain can be generated in activity electric wave variation, by record these electric waves become
Change the clinical detection that can be used for nervous system class disease, brain wave is also in the electric wave variation of record.In the frequency model of brain wave
In enclosing, 1-30HZ is in addition to this spontaneous rhythmic brain activity can also be generated when brain carries out increasingly complex activity
The higher EEG signals of frequency, such as when absorbed Mr. Yu's part thing, it is easier to generate the brain wave of 25-100Hz wave band.It is logical
Cross the brain wave under different frequency is carried out the study found that the correlation of EEG signals and the brain cognitive activities of 40Hz or so very
By force (Wang Yonghong, Yang Hao, Dong Weiwei Analysis on 40 Hz ERP During Brain Transient Cognitive Performance, University Of Chongqing's journal (from
So science version), 2001 (02): 64-67.).And further investigations have shown that 40Hz brain wave has treatment Alzheimer disease
Potential ability (Increased EEG gamma band activity in Alzheimer ' s disease and mild
Cognitive impairment, Neural Transm (2008) 115:1301-1311).By comparing normal aging people and
Patients with Alzheimer disease is suffered from the EEG signals discovery for becoming literate and distinguishing the 40Hz generated in graphical event, Alzheimer's disease
The EEG signals of person 40Hz decreased significantly compared with normal aging people.Become literate and distinguish that simultaneously part Alzheimer can be improved in figure
The cognitive ability of patient shows the more stronger 40Hz brain wave than before.So might as well be lured by the direct stimulation of outer medium
The EEG signals that brain generates strong 40Hz are led, the cognitive ability of Lai Tigao brain, this may be treatment Alzheimer disease
Another effective way.
Summary of the invention
Mesh of the present invention proposes a kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease, for Alzheimer sufferer
The Treatment need of person solves the difficult medical problem for not having specific physical therapy modalities.
Technical solution of the invention is as follows:
A kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease, including arc shell, radiator grille, round earmuff, light source,
Sound source, signal amplify drive module, control module, power supply, and the control module generates signal all the way and drives as signal amplification
The input of module, signal generates two-way driving signal by signal amplification drive module and respectively drives light source and sound source, due to letter
Number only by signal amplification drive module amplification and signal conversion, the two-way driving signal frequency of generation be it is identical, this
Sample is always consistent to guarantee the light exported and acoustic resonance frequency, and the key of control module and knob can change light source
With frequency, light intensity, colour temperature and the volume of sound source.The power supply has independent control switch to can be controlled separately light source and sound source,
The two is separated to work independently.It stimulates, allows to further increase light source to the induction of the 40Hz EEG signals of brain
Patient is in the state focused in therapeutic process brain, then pass through control module control light source formed it is clockwise and inverse
The running lamp of hour hands checker allows patient's right and left eyes that light source is followed to change direction respectively and carries out eyeball training, Lai Zengqiang 40Hz
The generation of EEG signals.
Preferably, in order to adapt to individual caused by many factors such as different age group and education level, job specification
Difference, the signal generator can be by the frequency of control module key change output signal, and then changes light source harmony
The output frequency in source accomplishes that 35-45Hz range is adjustable, and default acousto-optic resonant frequency is 40Hz, to be suitable for most of illness
Crowd.
Preferably, in order to guarantee that the light generated and sound frequency are consistent, signal amplifies the two-way that drive module generates
Driving signal frequency is identical.
Preferably, in order to reduce the interference to light source of external environment, the radiator grille for installing light source is opaque, can stop
Ambient light enters.
Preferably, in order to meet patient to bright and volume comfort level, light source and sound source can pass through control module key
Change bright, colour temperature and volume with knob.
Preferably, it is contemplated that some patients are for the different acceptance levels of illumination and sound, and power supply is equipped with to light source harmony
The independent control switch in source.
Preferably, running lamp of the light source design at checker clockwise and anticlockwise, the attention of Lai Tigao patient, more
Good induction brain generates 40Hz EEG signals.
The beneficial effects of the present invention are:
1, the therapeutic equipment passes through the optical signal and acoustical signal collective effect of identical frequency, generates vision to brain in patients and the sense of hearing is pierced
Swash, while light source design improves the attention of patient at the running lamp of checker clockwise and anticlockwise, induction patient is big
Brain generates stronger 40Hz EEG signals, further increases the cognitive ability of brain in patients, and the frequency of light source and sound source can
To adjust within the scope of 35-45Hz, the individual difference difference of different brain in patients can adapt in this way, to reach better treatment
Effect.
2, the therapeutic equipment improves curative effect in treatment and makes the patient feels more comfortable, installs before light source
Cover can block interference of the external environment to light source, and light source and the light of sound source, colour temperature and volume can be adjusted, the two
Also there is the switch individually controlled, it, can also be single if patient can not receive visual stimulus or a certain of auditory stimulation
This is solely closed, it in this way can be preferably using treatment for the visual stimulus patient different with auditory stimulation acceptance level
Instrument.
3, the therapeutic equipment has small in size, the advantage that structure is simple, easy to carry.
Detailed description of the invention
Fig. 1 shows the structural schematic diagram of the therapeutic equipment；
Fig. 2 shows the structure charts of the therapeutic equipment light source；
Fig. 3 shows the therapeutic equipment sound source structure chart；
Fig. 4 shows the structure chart of the therapeutic equipment radiator grille and light source；
Fig. 5 shows the schematic diagram of the therapeutic equipment；
Fig. 6 shows the signal amplification drive module schematic diagram of the therapeutic equipment.
Detailed description of the invention: shown in Fig. 1,1 is arc shell, and 2 be radiator grille, and 3 be round earmuff, and 8 be control module, Fig. 2 institute
Show, 4 be a lamp bead of light source, and the lamp bead that can see light source in figure is distributed the oval ring of light, and shown in Fig. 3,3 be round ear
Cover, 5 be sound source, and sound source is mounted in inside round earmuff as we can see from the figure, and shown in Fig. 4,2 be radiator grille, and 4 be light
Source, it can be seen from the figure that the lamp bead of light source is forward-mounted above cover.
Specific embodiment
Below in conjunction with attached drawing, present invention is further described in detail.
Referring to figs. 1 to 5, a kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease, comprising: arc shell
1, radiator grille 2, round earmuff 3, light source 4, sound source 5, signal amplification drive module 6, control module 7 and power supply 8；Wherein light source 4
The colour temperature of the frequency of the key and knob of control module 7 adjustment acousto-optic, power and light can be passed through with sound source 5.The treatment
It is radiator grille 2 and light source 4 before instrument, radiator grille 2 can effectively prevent interference of the external environment to light source 4, improve therapeutic effect.
The position of ear in two sides is round earmuff 3 and sound source 5, can generate sound, and in round 3 outside of earmuff, there is control light
The key and knob of the frequency and intensity of source 4 and sound source 5.
Wherein, it there are two light source 4 is set, is located in front of wearer's left eye and right eye, over the course for the treatment of in order to improve
Light source 4 is designed to the running lamp of checker clockwise and anticlockwise by the attention of brain in patients, and each light source 4 is by 10
Lamp bead forms two oval apertures, and outer ring is made of 6 lamp beads, and inner ring is made of 4 lamp beads, and the oval aperture of inside is big
It is small close with human eye size, interference of the external environment to light source 4 when radiator grille 2 is used to install light source 4 and reduces treatment.Signal is put
Big drive module 6 is made of constant current voltage stabilizing circuit and power amplification circuit two parts, and constant current voltage stabilizing circuit is used to drive light source 4,
The driving chip that its circuit is mainly used is the LM3402 of TI company, which can at most drive 15 lamp beads, driving
Size of current is 0.5A, and for power amplification circuit for driving sound source 5, the driving chip that circuit is mainly used is TI company
LM4889, the chip are capable of providing the consecutive mean power output of 1W, can be used in driving sound source 5.What control module 7 used
STM32F407 microprocessor, the processor host frequency reach 168MHZ, and the I/O mouth that can be used has 102, and be up to 12 fixed
When device can be used, by judging whether the spilling number of timer interruption of control module reaches the frequency number of setting, control
I processed O mouthfuls output low and high levels generate the adjustable pulse drive signals of frequency, due to frequency range be 35-45HZ, the period
Time range is 22.2-28.6ms, thus by enter timer interruption after I O output voltage direction negate, setting output letter
Number duty ratio is 50%, and the time for entering timer interruption twice in this way is a cycle time, by key control timer
The disconnected time changes the frequency of output signal, presses key pressing frequency shift 0.5Hz, 7 I/O mouthfuls of output signal of control module every time
Size of current can achieve 10mA, and output voltage size can achieve 3.6V, and port output signal can drive as signal amplification
The input signal of dynamic model block 6 uses.
The key control output end mouthful that the present invention passes through control module 7 when in use generate all the way driving signal as signal
Amplify the input of drive module 6, signal amplifies the identical two-way driving signal of 6 output frequency of drive module, this two paths of signals point
Not Qu Dong light source 4 and sound source 5 generate light and sound, the suitable frequency of key and knob adjustment that then patient passes through control module 7
After the colour temperature of rate, intensity and light, the running lamp of light source panel and light source 4 of following one wherever one goes in front of eye gaze is kept to change direction
Carry out eyeball training, the single therapy time is no more than a hour, after take therapeutic equipment and complete seance.
Claims (2)
1. a kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease, shape includes: for dressing and installing other lists
The arc shell (1) of member is placed on arc shell (1) and is previously used for the radiator grille (2) of installation light source (4), is placed on outside arc
Shell (1) two sides are used to install the round earmuff (3) of sound source (5), and structure includes: for luminous light source (4), for sounding
Sound source (5), and what is be connected with light source (4) and sound source (5) are used to drive light source (4) and the signal of sound source (5) to amplify drive module
(6), the input signal of signal amplification drive module (6) is generated by the control module (7) that is attached thereto and control module (7) can be with
Unlike signal is generated with meet demand, is responsible for power supply and is connected with the power supply (8) of switch with control module (7), wherein light source (4) position
Before arc shell (1), close to the position for wearing patient's eye, sound source (5) is located at arc shell (1) two sides, close to wearing
The position of two ear of patient, other parts are located at arc shell (1) below, wear patient's hindbrain position, it is characterised in that light source (4)
The oval ring of light being made of 10 lamp beads, the ring of light are divided into inside and outside two circle, and inner ring is made of 4 lamp beads, and outer ring is by 6
Lamp bead composition, and respectively have one group of light source (4) in front of wearer's left eye and right eye, drive the amplification of the signal of light source (4) and sound source (5)
Drive module (6) is made of constant current voltage stabilizing circuit and power amplification circuit two parts, and wherein constant current voltage stabilizing circuit is for driving light
Source (4), power amplification circuit is for driving sound source (5), and the input signal of signal amplification (6) two parts of drive module is derived from
Control module (7) same output end makes the driving signal of light source (4) and sound source (5) have identical frequency.
2. a kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease according to claim 1, it is characterised in that light
The driving frequency range of source (4) and sound source (5) is 35-45Hz.
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| CN201910648213.8A CN110251798A (en) | 2019-07-18 | 2019-07-18 | A kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease |
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| CN201910648213.8A CN110251798A (en) | 2019-07-18 | 2019-07-18 | A kind of wear-type acousto-optic therapeutic equipment for Alzheimer disease |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110639131A (en) * | 2019-11-07 | 2020-01-03 | 杭州崇正医疗科技有限公司 | Glasses type acousto-optic treatment equipment for Alzheimer's disease |
| CN111317904A (en) * | 2020-03-14 | 2020-06-23 | 刘艳娟 | A treatment device for treating alzheimer's disease |
| CN111467641A (en) * | 2020-05-27 | 2020-07-31 | 黄勇 | Acousto-optic compound therapy implementation device |
| CN111569270A (en) * | 2020-05-27 | 2020-08-25 | 黄勇 | Compound phototherapy implementation device |
| CN111939483A (en) * | 2020-08-13 | 2020-11-17 | 常州亚当生物技术有限公司 | Photoacoustic and electromagnetic integrated treatment system |
| CN113018636A (en) * | 2021-01-18 | 2021-06-25 | 厦门大学附属翔安医院 | Acousto-optic program-controlled stimulation device for treating post-stroke depression through visual-auditory coupling |
| CN113101493A (en) * | 2021-05-08 | 2021-07-13 | 宁波市康宁医院(宁波市精神疾病预防控制中心、宁波市微循环与莨菪类药研究所) | Adjustable-frequency Alzheimer disease improvement eyeshade |
| CN113274613A (en) * | 2021-06-30 | 2021-08-20 | 胡柳俊 | Acousto-optic induction brain vision device |
| CN113694395A (en) * | 2021-09-07 | 2021-11-26 | 安徽中实华粹医疗器械有限公司 | Frequency adjustable electric vibration infrared music therapeutic instrument |
| CN116099098A (en) * | 2022-11-01 | 2023-05-12 | 南京蔚来思创科技有限公司 | Acousto-optic induction electroencephalogram treatment equipment |
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