CN115708919A - Nerve stimulation regulation and control device and method based on Bluetooth remote controller - Google Patents
Nerve stimulation regulation and control device and method based on Bluetooth remote controller Download PDFInfo
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Abstract
The invention discloses a neural stimulation regulation and control device and method based on a Bluetooth remote controller, which comprises the following steps: the system comprises a Bluetooth remote controller, an acoustic-optical-electric combined stimulation integrated main device and an acoustic-optical-electric combined stimulation wearable device, wherein the Bluetooth remote controller is independently connected with the acoustic-optical-electric combined stimulation integrated main device so as to regulate acoustic-optical-electric combined stimulation parameters and/or implement cognitive psychometric scale evaluation and education training; the Bluetooth remote controller is independently connected with the acoustic-optical-electrical stimulation wearable equipment to control the LED lamp cap, the earphone and the electrode of the wearable equipment to be switched on and off; the stimulation parameters are adjusted by using a Bluetooth remote controller brain-computer interface and a two-step remote control method, so that the real-time curative effect perception and the stimulation parameter adjustment and control are synchronous to form a closed loop. Through the mode, the neural stimulation regulation and control device and method based on the Bluetooth remote controller improve the flexibility and timeliness of controlling acousto-optic electric stimulation, enable real-time curative effect perception and stimulation parameter regulation and control to form a closed loop synchronously, and improve the corresponding treatment effect.
Description
Technical Field
The invention relates to the technical field of nerve stimulation regulation, in particular to a nerve stimulation regulation device and method based on a Bluetooth remote controller convenient for a patient to operate.
Background
The clinical manifestations of neurological and cognitive dysfunction include tinnitus, deafness, insomnia, anxiety, depression, epilepsy, vertigo, migraine, nerve fatigue, distraction, confusion, unresponsiveness, paranoia, obsessive compulsive, schizophrenia, hyperactivity, self-imposed, memory deterioration, dementia, etc.
Neurological and cognitive dysfunction, which usually involves the cross-effects of objective physiology and subjective psychology, is the disease with the highest incidence and the highest medical insurance burden in the elderly society and is mainly characterized by highly individualized neuropsychiatric slowness, unclear pathogenesis and lack of effective drugs.
As a first generation technology, non-invasive single physical factor stimulation intervention treatment product technologies, such as transcranial electrical stimulation, transcranial near infrared light stimulation, stimulation of deep brain central nuclei through ear canals and transformation of the electrical physiological signals into electrical physiological signals through cochlea, and the like, are clinically accepted due to safety, certain curative effects on a certain single disease and various subjective evaluation scales.
The main pain points currently in clinical testing, treatment and assessment are: the stimulation of a single physical factor is difficult to effectively stimulate a plurality of target points distributed on multiple levels and positions of a brain neural network simultaneously and lacks the real-time objective detection and evaluation of the physical stimulation intervention treatment effect, so that the treatment effect covering the range of the diseases of the neural and cognitive dysfunction and the refractory syndrome is limited. Because most conditions of neurological and cognitive dysfunction involve objective physiological and subjective psychological interactions of multiple deep brain central nuclei and multiple shallow cerebral cortex, and it is often a condition that accompanies multiple other conditions, including but not limited to tinnitus sleep anxiety syndrome, vertigo depression cognitive syndrome.
In the prior art, a patent with application number 201210303152.X discloses a device for treating deafness and tinnitus, which treats the deafness and tinnitus by sound and light, and comprises a pure-tone audiometric acoustic impedance instrument, a red-light therapeutic instrument and a sound spectrum resonance therapeutic instrument which are separately and independently operated, wherein the pure-tone audiometric acoustic impedance instrument is a common pure-tone audiometer for detecting hearing loss; the red light therapeutic instrument adopts red visible light wave band with wavelength of 600-700 nm as main part to irradiate, and is not stimulated by near infrared light pulse; the acoustic spectrum resonance therapeutic apparatus is a sound, heat, electric and magnetic micro massager for ear, combines traditional Chinese medicine fumigation and acupuncture for physical therapy, is not multi-channel multi-modal acoustic stimulation based on audio modulation, and is not transcranial electric or magnetic stimulation with pulse waveforms. The traditional physical therapy equipment only carries out micro massage on the body surface of the ear, and can not stimulate deep brain nuclei nor cortex of multiple brain regions; the above physiotherapy methods are simple superposition of traditional Chinese medicine physiotherapy methods, are not based on noninvasive nerve regulation and control of quantitative and adjustable sound-light combined stimulation which is individually formulated according to the nerve electrophysiology principle and detection of patients with nerve and cognitive dysfunction diseases, cannot be combined with biofeedback electroencephalogram (EEG) detection, and cannot enable perception and treatment regulation and control of the patients to form a closed loop.
Therefore, the brain neural network acousto-optic-electrical multi-physical factor time-frequency space-frequency multi-dimensional stimulation neural regulation paradigm combined with biofeedback real-time detection and evaluation is an important way for expanding the coverage of treatment of neurological and cognitive dysfunction diseases and solving intractable syndromes, but involves comprehensive control of a transcranial electrical stimulation cortex, a transcranial light stimulation cortex and an acoustic stimulation central nucleus, at present, no simple device or method can be used for simultaneously performing combined stimulation of sound, light and electricity on a patient to treat neurological and cognitive dysfunction, so that the curative effect and the disease coverage are limited, the participation degree of the patient is low, the curative effect perception is not timely, and popularization and application of a multi-physical factor stimulation technology are not facilitated, and improvement is needed.
Disclosure of Invention
The invention mainly solves the technical problem of providing a nerve stimulation regulation and control device and method based on a Bluetooth remote controller, which flexibly control sound, light and electrical stimulation combined switches and parameter adjustment, so that real-time curative effect perception and stimulation parameter regulation and control synchronously form a closed loop to enhance and optimize curative effect.
In order to solve the technical problems, the invention adopts a technical scheme that: the utility model provides a neural stimulation regulation and control device and method based on a Bluetooth remote controller, comprising the following steps: the acoustic-photoelectric combined stimulation integrated main equipment comprises a main control MCU, an optical signal regulation and amplification processing module, an optical stimulation signal output module, an acoustic signal regulation and amplification processing module, a multi-channel acoustic signal synthesis processing module, an electric signal stabilization current-limiting processing module and an electric stimulation signal output module, wherein the acoustic-photoelectric combined stimulation integrated main equipment comprises an LED lamp cap, an earphone and an electrode, the main control MCU is connected with the optical signal regulation and amplification processing module to perform optical signal oscillation regulation and amplification processing, the optical stimulation signal output module is connected between the optical signal regulation and amplification processing module and the LED lamp cap, emits oscillation or flickering through the LED lamp cap, stimulates a superficial cerebral cortex, the optical signal regulation and amplification processing module is connected with the optical signal regulation and amplification processing module to perform optical signal oscillation regulation and amplification processing, the optical stimulation signal output module is connected with the LED lamp cap through the LED lamp cap, and converts the optical signal into acoustic signal through a deep acoustic signal, the acoustic signal synthesis processing module and current-limiting processing module through an auditory nerve stimulation signal synthesis processing module, the optical signal synthesis processing module and current-limiting processing module and the optical signal output module are converted into a deep acoustic signal through an auditory signal synthesis processing module, and a physiological signal synthesis processing module are performed through a physiological signal synthesis circuit, and performing electric signal stable current limiting, wherein the electric stimulation signal output module is connected between the electric signal stable current limiting processing module and the electrode, outputting an oscillation electric stimulation signal according to a set waveform, sending micro-stimulation current through the electrode, performing transcranial electric stimulation on the superficial cerebral cortex, and establishing a cranial nerve network acoustic-photoelectric multi-physical factor time-frequency space multi-dimensional stimulation nerve regulation paradigm.
In a preferred embodiment of the present invention, a first bluetooth communication module for communicating with a bluetooth remote controller is disposed in the integrated main device.
In a preferred embodiment of the present invention, a second bluetooth communication module for communicating with a bluetooth remote controller is disposed in the acoustic-optical-electrical stimulation wearable device.
In a preferred embodiment of the present invention, the bluetooth remote controller is provided with a touch screen, a control button or a voice sensor.
In a preferred embodiment of the invention, the pulse flicker frequency of the LED lamp cap is adjusted within a range of 10Hz to 40Hz.
In a preferred embodiment of the invention, the volume of the earphone is adjusted within a range of 0 to 100dB HL.
In a preferred embodiment of the invention, the current magnitude regulation range of the electrode is 0 to 2mA, and the electrical stimulation signal output module adopts a direct current stimulation signal output module or an alternating current stimulation signal output module.
In order to solve the technical problem, the invention adopts another technical scheme that: the neural stimulation regulation and control device based on the Bluetooth remote controller comprises the following steps:
the Bluetooth remote controller is independently connected with the sound-light-electricity combined stimulation integrated main equipment to regulate and control sound-light-electricity combined stimulation parameters and/or implement cognitive psychometric scale evaluation and education training;
the Bluetooth remote controller is independently connected with the acoustic-optical-electrical stimulation wearable equipment to control the LED lamp cap, the earphone and the electrode of the wearable equipment to be switched on and off;
the stimulation parameters are adjusted by using a Bluetooth remote controller and a two-step remote control method, so that real-time curative effect perception and stimulation parameter regulation and control synchronously form closed-loop interaction, the regulation and control flexibility and timeliness are enhanced, and the curative effect is further optimized:
the first step, brain-computer interface and common remote control operation method: according to individual detection and/or curative effect perception of a patient, an initial stimulation combination mode and/or stimulation parameters are set and/or regulated according to a big data deep learning algorithm through the sound-light-electricity combined stimulation integrated main equipment, and non-professional-level intelligent sound-light-electricity combined stimulation and stimulation parameter regulation are automatically implemented;
secondly, a professional remote control operation method: the sound, light and electric stimulation parameters are subjected to professional-level manual individualized and accurate stimulation parameter adjustment one by one, and even the adjustment of sound, light and electric stimulation signal generation and processing processes and parameters is expanded; a patient with insufficient learning and/or handling capacity or severe cognitive impairment may be assisted by a specialist or third party in manipulating the bluetooth remote control;
in the amazing treatment process, the patient receives voice command through brain computer interface module in the bluetooth remote controller, relevant perception button or speech sensor when using as the transponder according to the treatment effect of subjective perception or the treatment effect that the contrast is expected, triggers that the amazing integration master unit of sound photoelectricity combination presets amazing parameter adjustment logic algorithm embedding software, and the amazing parameter is excited in real time, convenient, direct regulation and control: (1) If the patient is unfamiliar with and/or cannot operate complicated sound-light-electricity stimulation parameter adjustment and/or has non-difficult miscellaneous disease symptoms, universal intelligent remote control stimulation parameters can be automatically carried out directly by adopting a first step common remote control operation method; (2) If the patient is familiar with and/or can operate complicated sound-light-electricity stimulation parameter adjustment and/or has difficult miscellaneous disease symptoms, a second professional remote control operation method can be entered, and individual precise remote control stimulation parameter adjustment is manually carried out one by one; the stimulation parameters are iteratively regulated and controlled by a two-step remote control method, so that the digital control of subjective curative effect perception is realized, the curative effect is optimized, and more patients and more diseases are covered.
In a preferred embodiment of the invention, before, in the middle and at the later period of clinical sound-light-electricity stimulation treatment, a patient can operate a Bluetooth remote controller to evaluate a questionnaire table and educate psychological cognitive training, questionnaire table evaluation instructions are pushed by sound-light-electricity combined stimulation integrated main equipment through Bluetooth, an questionnaire table evaluation interface is automatically displayed on a Bluetooth remote controller end interface or the sound-light-electricity combined stimulation integrated main equipment, the patient answers or fills in one by one through a touch screen, a regulation button or a voice sensor on the Bluetooth remote controller, and filling information is returned and filled in real time through the Bluetooth; the psychology cognition education training instructions are pushed by the sound-light-electricity combined stimulation integrated main equipment through the Bluetooth, a patient looks up psychology cognition education training data on a Bluetooth remote controller end or the sound-light-electricity combined stimulation integrated main equipment, relevant psychology cognition training and education are completed through interaction of the Bluetooth remote controller, and information is returned to the sound-light-electricity combined stimulation integrated main equipment through the Bluetooth in real time.
In a preferred embodiment of the invention, the stimulation parameter is regulated, controlled and responded by the patient through the communication between the Bluetooth remote controller and the acousto-optic electrical stimulation wearable device, so that the digitization of curative effect perception is realized, the treatment is converted into interactive, intelligent, synchronous and humanized operation of nerve stimulation parameter regulation, the enthusiasm and subjective potential of the patient actively participating in nerve regulation and control treatment are mobilized, the negative cognitive psychological influence of nerve and cognitive dysfunction is favorably reduced, the confidence of the patient in maintaining treatment is enhanced, the cognitive psychology of the patient is effectively regulated or remodeled and is recovered to a normal state, the curative effect of the chronic disease with nerve and cognitive dysfunction is further improved, and the recovery time is shortened.
The invention has the beneficial effects that: the invention provides a nerve stimulation regulation and control device and method based on a Bluetooth remote controller, wherein a patient or a technician can be independently connected with a sound-light-electricity combined stimulation integrated main device by using the multifunctional Bluetooth remote controller in the process of carrying out sound-light-electricity combined stimulation nerve regulation and control to regulate and control stimulation parameters and/or carry out cognitive psychology scale evaluation and education training, can be independently connected with a sound-light-electricity stimulation wearable device to directly operate a switch of sound, light and electricity stimulation, and improve the flexibility and timeliness of controlling sound-light-electricity stimulation, and can also be used as a responder of the patient during detection and treatment to enhance real-time curative effect perception, so that the real-time curative effect perception and the stimulation parameter regulation are synchronously formed into a closed loop, the stimulation parameters are optimized and regulated to improve the corresponding treatment effect, an interactive treatment mode is formed to mobilize the positivity and the rehabilitation of the patient actively participating in nerve regulation and treatment, the negative cognitive psychology influence of the nerve and cognitive dysfunction is favorably reduced, the confidence of the patient who keeps treating the nerve and effectively adjusts the cognitive psychology of the patient and recovers to a normal state, the curative effect of the nerve and the cognitive dysfunction is further improved, and the recovery time is shortened.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a schematic diagram of a preferred embodiment of a nerve stimulation control device based on a Bluetooth remote controller according to the present invention;
FIG. 2 is a diagram of a preferred embodiment of a method for regulating and controlling neural stimulation based on a Bluetooth remote controller according to the present invention;
fig. 3 is a schematic diagram of the operation principle of the bluetooth remote controller in fig. 1.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 3, an embodiment of the invention includes:
the neural stimulation regulation and control device and method based on the bluetooth remote controller as shown in fig. 1 comprises: the Bluetooth remote controller is internally provided with a brain interface module, and the Bluetooth remote controller regulates and controls stimulation parameters of the sound-light-combined-stimulation integrated main equipment and/or regulates and controls stimulation combination of the sound-light-combined-stimulation integrated main equipment and/or responds to stimulation treatment perception of a patient based on a brain interface technology, wherein in the embodiment, the Bluetooth remote controller is provided with a touch screen, a regulation key or a voice sensor, and as shown in figure 3.
In this embodiment, be provided with the first bluetooth communication module that carries out the communication with the bluetooth remote controller in the amazing integration master equipment of sound light combination, be provided with the second bluetooth communication module that carries out the communication with the bluetooth remote controller in the wearable equipment of sound light combination. The Bluetooth module in the Bluetooth remote controller is a highly integrated BLE4.2 based on a Nordic nRF52832 scheme, is specially designed for wireless 2.4GHz ISM high-speed transmission, supports UART serial port data transparent transmission, has 32-bit ARM Cortex-M4F CPU, flash memory, analog computers and digital computer peripheral equipment, supports classic Bluetooth and low-power-consumption Bluetooth, is downward compatible with a common version, and has the advantages of longer transmission distance, smaller power consumption, smaller delay and the like. The method comprises the steps that firstly, a Bluetooth module is initially programmed when being electrified, the Bluetooth module enters a slave mode, after the Bluetooth module is connected with an acousto-optic-electric combined stimulation integrated main device, corresponding display output and treatment control output are made according to key input (namely, functional requirements) or a voice command is received through a voice sensor, the display can be simultaneously displayed on a touch screen of a Bluetooth remote controller and a display screen end of the acousto-optic-electric combined stimulation integrated main device, and parameters such as electrical stimulation current, acoustic stimulation volume, optical stimulation pulse flicker frequency and the like are adjusted and displayed;
the Bluetooth remote controller is divided into a touch screen operation type and a key operation type, the touch screen of the Bluetooth remote controller can display control contents in real time, and data and sound-light-electricity combined stimulation integrated main equipment are completely consistent;
control mode selection is carried out through the Bluetooth remote controller: three keys correspond to a master mode, a slave mode and a loop back mode, clicking is effective, and one key is selected in three modes;
a main mode: actively searching and connecting other Bluetooth modules to receive and transmit data;
from the mode: can only be searched and connected by other Bluetooth modules to receive and transmit data;
loop back mode: the Bluetooth module returns the received data to the remote sound-light-electricity combined stimulation integrated main equipment, and can program the module in an initialization state to enable the module to be in a required working mode;
the sound, light and electricity correspond to the control switch: the size can be adjusted after long-time pressing on or off and clicking.
The sound-light-electricity combined stimulation integrated main equipment comprises a main control MCU, a light signal regulation and amplification processing module, a light stimulation signal output module, an acoustic signal regulation and amplification processing module, a multi-channel acoustic signal synthesis processing module, an electric signal stabilization current-limiting processing module and an electric stimulation signal output module, wherein the sound-light-electricity combined stimulation wearable equipment comprises an LED lamp holder, an earphone and an electrode, the main control MCU is connected with the light signal regulation and amplification processing module to perform light signal oscillation regulation and amplification processing, the light stimulation signal output module is connected between the light signal regulation and amplification processing module and the LED lamp holder to emit oscillating or flickering near infrared light through the LED lamp holder to stimulate the superficial cerebral cortex through the skull, in the embodiment, the pulse flickering frequency of the LED lamp holder is in the range of 10Hz-40Hz, and in the light stimulation mode, the pulse flickering frequency is controlled to change in the range of 10Hz-40Hz through a remote controller + or-step by 1.0Hz;
the main control MCU is connected with the acoustic signal regulation and control processing module to perform acoustic signal modulation and waveform regulation and control processing, the multi-channel acoustic signal synthesis processing module is connected between the acoustic signal regulation and control processing module and the earphone, sounds are emitted through the earphone, and the sounds are converted into electrophysiological signals through the auditory canal through a cochlea to stimulate the deep brain central nucleus, in the embodiment, the volume of the earphone is regulated within the range of 0-100dB HL, and under the acoustic stimulation mode, the volume is controlled to change within the range of 0-100dB HL through a Bluetooth remote controller + or-and is stepped by 1.0dB HL;
the main control MCU is connected with the electric signal stable current limiting processing module to perform stable current limiting on the electric signal, the electric stimulation signal output module is connected between the electric signal stable current limiting processing module and the electrode, and sends out stimulation micro-current through the electrode to perform transcranial electric stimulation on the superficial cerebral cortex, in the embodiment, the current of the electrode is adjusted within the range of 0-2mA, and in the electric stimulation mode, the current can be changed within the range of 0-2mA through the Bluetooth remote controller or-controlled current, and is stepped by 0.1mA, so that the safety is ensured.
As shown in fig. 2, the method for regulating and controlling nerve stimulation based on a bluetooth remote controller, which uses the apparatus for regulating and controlling nerve stimulation based on a bluetooth remote controller in fig. 1, includes the following steps:
the Bluetooth remote controller is independently connected with the sound-light-electricity combined stimulation integrated main equipment to regulate and control sound-light-electricity combined stimulation parameters and/or implement cognitive psychometric scale evaluation and education training; before, during and after the clinical acousto-optic and electric stimulation treatment, a patient can operate a Bluetooth remote controller to perform questionnaire scale evaluation and psychological cognitive training education, questionnaire scale evaluation instructions are pushed by the acousto-optic and electric combined stimulation integrated main equipment through Bluetooth, a questionnaire scale evaluation interface is automatically displayed on a Bluetooth remote controller end interface or the acousto-optic and electric combined stimulation integrated main equipment, the patient answers or fills in the questionnaire scale one by one through a touch screen, a control button or a voice sensor on the Bluetooth remote controller, and filling information is returned through the Bluetooth in real time; the method comprises the following steps that a psychosocial education training instruction is pushed by sound-light-electricity combined stimulation integrated main equipment through Bluetooth, a patient looks up psychosocial education training data on a Bluetooth remote controller end or the sound-light-electricity combined stimulation integrated main equipment, related psychosocial education training and education are completed through interaction of a Bluetooth remote controller, and information is returned to the sound-light-electricity combined stimulation integrated main equipment through the Bluetooth in real time;
the Bluetooth remote controller is independently connected with the acoustic-optical-electrical stimulation wearable equipment to control the LED lamp cap, the earphone and the electrode of the wearable equipment to be switched on and off;
the stimulation parameters are adjusted by using a Bluetooth remote controller and a two-step remote control method, so that the real-time curative effect sensing and the stimulation parameter regulation and control synchronously form closed-loop interaction, the regulation and control flexibility and timeliness are enhanced, and the curative effect is further optimized:
the first step, brain-computer interface and common remote control operation method: according to individual detection and/or curative effect perception of a patient, an initial stimulation combination mode and/or stimulation parameters are formulated and/or regulated according to a big data deep learning algorithm through the acoustic-optical-electric combined stimulation integrated main equipment, and non-professional-level intelligent acoustic-optical-electric combined stimulation and stimulation parameter regulation are automatically implemented;
step two, a professional remote control operation method: the sound, light and electric stimulation parameters are subjected to professional-level manual individualized and accurate stimulation parameter adjustment one by one, and even the adjustment of sound, light and electric stimulation signal generation and processing processes and parameters is expanded; a patient with insufficient learning and/or handling capacity or severe cognitive impairment may be assisted by a specialist or third party in manipulating the bluetooth remote control;
in amazing treatment process, the patient receives voice command through brain-computer interface module among the bluetooth remote controller, relevant perception button or speech sensor when using as the responder according to the treatment effect of subjective perception or the treatment effect that contrast expectation, triggers the amazing integration master unit of sound photoelectricity combination and presets amazing parameter adjustment logic algorithm embedding software, and the amazing parameter is swashed in real time, convenient, direct regulation and control: (1) If the patient is not familiar with and/or can not operate the complex sound, light, electricity and stimulation parameter adjustment and/or has the diseases without difficult and complicated symptoms, the universal intelligent remote control stimulation parameters can be automatically carried out by directly adopting a first step common remote control operation method; (2) If the patient is familiar with and/or can operate complicated sound-light-electricity stimulation parameter adjustment and/or has difficult miscellaneous disease symptoms, a second professional remote control operation method can be entered, and individual precise remote control stimulation parameter adjustment is manually carried out one by one; as shown in fig. 2, the stimulation parameters are iteratively regulated and controlled by a two-step remote control method to realize the digital control of subjective curative effect perception and optimize the curative effect, so as to cover more patients and more diseases.
Perception response: as shown in fig. 3, in the stimulation treatment process, the user can click or receive a voice command through selection of different keys on the bluetooth remote controller, respond to the detection or treatment perception, display response content on a touch screen of the bluetooth remote controller and/or a display screen of the integrated main device of the sound, light and electricity combined stimulation, and automatically record the perception of the patient.
As shown in fig. 1, the patient controls the communication between the bluetooth remote controller and the wearable acousto-optic electrical stimulation device to regulate and respond stimulation parameters, so that the digitization of the treatment effect perception is realized, the communication is converted into interactive, intelligent, synchronous and humanized operation of the regulation and control of the nerve stimulation parameters, the enthusiasm and subjective potential of the patient actively participating in the nerve regulation and control treatment are mobilized, the negative cognitive psychological influence of the nerve and cognitive disorder is favorably reduced, the confidence of the patient in maintaining the treatment is enhanced, the cognitive psychology of the patient is effectively regulated or remodeled and is recovered to a normal state, the treatment effect of the chronic disease with the nerve and cognitive disorder is further improved, and the recovery time is shortened.
In conclusion, the neural stimulation regulation and control device and method based on the Bluetooth remote controller improve the interactive participation of patients, and patients or technicians can perform parameter regulation and control and sensing response of sound-light-electricity combined stimulation through the Bluetooth remote controller to form a closed loop of real-time curative effect sensing and parameter regulation and control, so that the device and method are favorable for optimizing parameters of neural stimulation, accelerating remodeling or recovering normal cognitive psychology, and improving the treatment and recovery effects on neural and cognitive dysfunction.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, or direct or indirect applications in other related fields, which are made by the contents of the present specification, are included in the scope of the present invention.
Claims (10)
1. A neural stimulation regulation and control device based on a Bluetooth remote controller is characterized by comprising: the integrated sound-light-electricity combined stimulation main equipment comprises a main control MCU, an optical signal regulation and amplification processing module, an optical stimulation signal output module, an acoustic signal regulation and control processing module, a multi-channel acoustic signal synthesis processing module, an electric signal stable current limiting processing module and an electric stimulation signal output module, the acoustic-optical-electrical stimulation wearable device comprises an LED lamp holder, an earphone and an electrode, wherein a master control MCU is connected with an optical signal regulation and amplification processing module for carrying out optical signal oscillation regulation and amplification processing, an optical stimulation signal output module is connected between the optical signal regulation and amplification processing module and the LED lamp holder, oscillation or flashing near infrared light is emitted through the LED lamp holder, the light signal is stimulated to the superficial cerebral cortex through a skull, the master control MCU is connected with an acoustic signal regulation and processing module for carrying out acoustic signal modulation and waveform regulation and processing, a multi-channel acoustic signal synthesis processing module is connected between the acoustic signal regulation and processing module and the earphone, the sound is emitted through the earphone, the sound is converted into an electrophysiological signal through an ear canal through a cochlea to stimulate a deep brain central nucleus, the master control MCU is connected with an electric signal stable current-limiting processing module for carrying out electric signal stable current limiting, the electrical stimulation signal output module is connected between the electrical signal stabilizing and current limiting processing module and the electrode, carries out electrical signal waveform processing, sends out micro-stimulation current through the electrode, electrically stimulates the superficial cerebral cortex through the skull, and establishes a cranial nerve network acoustic-photoelectric multi-physical factor time-frequency-space multi-dimensional stimulation nerve regulation paradigm.
2. The neural stimulation regulation and control device based on the Bluetooth remote controller according to claim 1, wherein a first Bluetooth communication module for communicating with the Bluetooth remote controller is arranged in the integrated main equipment.
3. The neural stimulation regulation and control device based on the Bluetooth remote controller according to claim 1, wherein a second Bluetooth communication module for communicating with the Bluetooth remote controller is arranged in the acousto-optic electric stimulation wearable device.
4. The nerve stimulation control device based on the Bluetooth remote controller according to claim 1, wherein the Bluetooth remote controller is provided with a touch screen, control buttons or a voice sensor, the touch screen displays control content in real time, the displayed data is consistent with the sound-light-electricity combined stimulation integrated main equipment,
mode selection is carried out through a Bluetooth remote controller:
a main mode: actively searching and connecting other Bluetooth modules to receive and transmit data;
from the mode: can only be searched and connected by other Bluetooth modules to receive and transmit data;
loop back mode: the Bluetooth module returns the received data to the remote sound-light-electricity combined stimulation integrated main equipment in an original state, and can be programmed in an initial state to be in a required working mode.
5. The neurostimulation control device based on the Bluetooth remote controller as claimed in claim 1, wherein the pulse flicker frequency of the LED lamp head is adjusted within a range of 10Hz to 40Hz.
6. The neural stimulation control device based on the Bluetooth remote controller according to claim 1, wherein the volume of the earphone is adjusted within 0 to 100dB HL.
7. The neural stimulation regulation and control device based on the Bluetooth remote controller according to claim 1, wherein the current regulation range of the electrode is 0-2mA, and the electrical stimulation signal output module adopts a direct current stimulation signal output module or an alternating current stimulation signal output module.
8. A neural stimulation control method based on a Bluetooth remote controller, which adopts the neural stimulation control device based on the Bluetooth remote controller as claimed in any one of claims 1 to 7, and is characterized by comprising the following steps:
the Bluetooth remote controller is independently connected with the sound-light-electricity combined stimulation integrated main equipment to regulate and control sound-light-electricity combined stimulation parameters and/or implement cognitive psychometric scale evaluation and education training;
the Bluetooth remote controller is independently connected with the acoustic-optical-electrical stimulation wearable equipment to control the LED lamp cap, the earphone and the electrode of the wearable equipment to be switched on and off;
the stimulation parameters are adjusted by using a Bluetooth remote controller and a two-step remote control method, so that real-time curative effect perception and stimulation parameter regulation and control synchronously form closed-loop interaction, the regulation and control flexibility and timeliness are enhanced, and the curative effect is further optimized:
the first step, brain-computer interface and common remote control operation method: according to individual detection and/or curative effect perception of a patient, an initial stimulation combination mode and/or stimulation parameters are formulated and/or regulated according to a big data deep learning algorithm through the acoustic-optical-electric combined stimulation integrated main equipment, and non-professional-level intelligent acoustic-optical-electric combined stimulation and stimulation parameter regulation are automatically implemented;
step two, a professional remote control operation method: the sound, light and electric stimulation parameters are subjected to professional-level manual individualized and accurate stimulation parameter adjustment one by one, and even the adjustment of sound, light and electric stimulation signal generation and processing processes and parameters is expanded; a patient with insufficient learning and/or handling capacity or severe cognitive impairment may be assisted by a specialist or a third party in manipulating the bluetooth remote control;
in the amazing treatment process, the patient receives voice command through brain computer interface module in the bluetooth remote controller, relevant perception button or speech sensor when using as the transponder according to the treatment effect of subjective perception or the treatment effect that the contrast is expected, triggers that the amazing integration master unit of sound photoelectricity combination presets amazing parameter adjustment logic algorithm embedding software, and the amazing parameter is excited in real time, convenient, direct regulation and control: (1) If the patient is not familiar with and/or can not operate the complex sound, light, electricity and stimulation parameter adjustment and/or has the diseases without difficult and complicated symptoms, the universal intelligent remote control stimulation parameters can be automatically carried out by directly adopting a first step common remote control operation method; (2) If the patient is familiar with and/or can operate complicated sound, light and electricity stimulation parameter adjustment and/or has difficult and complicated diseases, a second step of professional remote control operation method can be entered, and individualized and accurate remote control stimulation parameter adjustment is manually carried out one by one; the stimulation parameters are iteratively regulated and controlled by a two-step remote control method, so that the digital control of subjective curative effect perception is realized, the curative effect is optimized, and more patients and more diseases are covered.
9. The neural stimulation regulation and control method based on the bluetooth remote controller according to claim 8, wherein the patient can operate the bluetooth remote controller to perform questionnaire scale evaluation and psychological cognitive training education before, during and after clinical acousto-optic-electrical stimulation treatment, the questionnaire scale evaluation interface is automatically displayed on the end interface of the bluetooth remote controller or the acousto-optic-electrical combined stimulation integrated main device by pushing questionnaire scale evaluation instructions through bluetooth, and the patient answers or fills in one by one through a touch screen, a regulation button or a voice sensor on the bluetooth remote controller and returns filling information through bluetooth in real time; the psychosocial cognitive education training instructions are pushed by the sound-light-electricity combined stimulation integrated main equipment through Bluetooth, a patient looks up psychosocial cognitive education training data on a Bluetooth remote controller end or the sound-light-electricity combined stimulation integrated main equipment, relevant psychosocial cognitive training and education are completed through interaction of a Bluetooth remote controller, and information is transmitted back to the sound-light-electricity combined stimulation integrated main equipment through the Bluetooth in real time.
10. The neural stimulation regulation and control method based on the Bluetooth remote controller as claimed in claim 8, wherein the patient controls the communication between the Bluetooth remote controller and the acousto-optic electrical stimulation wearable device to regulate and respond the stimulation parameters, so as to realize digitization of curative effect perception, and convert the digital control into interactive, intelligent, synchronous and humanized operation of neural stimulation parameters, so as to mobilize the enthusiasm and subjective potential of the patient to actively participate in neural regulation and control treatment, which is beneficial to reducing negative cognitive psychological effects of nerve and cognitive impairment, enhancing the confidence of the patient in maintaining treatment, effectively adjusting or remodeling the cognitive psychology of the patient and recovering to a normal state, further improving the curative effect of chronic diseases with nerve and cognitive impairment and shortening the recovery time.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211612042.1A CN115708919A (en) | 2022-12-15 | 2022-12-15 | Nerve stimulation regulation and control device and method based on Bluetooth remote controller |
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| CN202211612042.1A CN115708919A (en) | 2022-12-15 | 2022-12-15 | Nerve stimulation regulation and control device and method based on Bluetooth remote controller |
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