CN110251642A - 一种具有治疗乳腺增生的自发热中药制剂 - Google Patents

一种具有治疗乳腺增生的自发热中药制剂 Download PDF

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CN110251642A
CN110251642A CN201910720942.XA CN201910720942A CN110251642A CN 110251642 A CN110251642 A CN 110251642A CN 201910720942 A CN201910720942 A CN 201910720942A CN 110251642 A CN110251642 A CN 110251642A
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许逸君
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Jiangsu Wanhong Health Technology Co Ltd
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Abstract

一种具有治疗乳腺增生的自发热中药制剂，其特征是包括中药组分、促渗透组分和自发热组分；所述中药组分的原料药材配方按重量份计，柴胡5‑15份、白芍10‑20份、香附10‑20份、荔枝核10‑20份、天门冬5‑15份、三棱10‑20份、莪术5‑15份、橘叶10‑20份、丹参5‑15份、半夏5‑15份、牡蛎粉10‑20份；所述促渗透组分为泊洛沙姆188、芒硝和月桂氮卓酮的组合物；所述促渗透组分与中药组分的质量比为1：3‑10；所述自发热组分为粒径为20至50μm的赭石粉；所述赭石粉与中药组分的质量比为1:3‑5。本发明的一种具有治疗乳腺增生的自发热中药制剂，可疏肝活血、软坚散结、消肿止痛；用于肝郁气结，气滞血瘀所引起的乳腺增生，乳核结节、胀痛。

Description

一种具有治疗乳腺增生的自发热中药制剂
技术领域
本发明涉及一种具有治疗乳腺增生的自发热中药制剂。
背景技术
乳腺病是妇女常见病，多发于中青年女性，发病率高达80％，在经期、哺乳期病情更为显著，主要表现为乳腺炎、乳腺增生、乳房肿块等。近几年，乳腺病呈上升趋势，而且癌变率极高，已成为女性健康的头号杀手。乳腺增生困扰着很多的女性，现在常用的治疗药物以疏肝理气化瘀散结为主，但治疗时间非常长，而且治愈后2个月左右乳房胀痛的感觉就会再次出现，其次就是服用激素类药物进行治疗，一般只能暂时缓解症状停止服药后疼痛感立即出现，而且长期服药对人的胃、肝、肾等器官的功能具有非常大的副作用。当前治疗该病的中药药物鱼目混杂，剂型单一，且治愈率低，易复发，有的毒副作用大，治疗周期长，费用高，或延误病情而发癌变，給患者造成很大的经济损失或精神损失。为了解决这一难题，人们在不断的进行探索和研究，尽管如此，现有中药制剂的治疗效果仍旧不能令人满意。
发明内容
本发明的目的是为了解决以上现有技术的不足，提出了一种具有治疗乳腺增生的自发热中药制剂。
本发明解决其技术问题所采用的技术方案是：一种具有治疗乳腺增生的自发热中药制剂，包括中药组分、促渗透组分和自发热组分；所述中药组分的原料药材配方按重量份计，柴胡5-15份、白芍10-20份、香附10-20份、荔枝核10-20份、天门冬5-15份、三棱10-20份、莪术5-15份、橘叶10-20份、丹参5-15份、半夏5-15份、牡蛎粉10-20份；所述促渗透组分由泊洛沙姆188、芒硝和月桂氮卓酮的组成；所述促渗透组分与中药组分的质量比为1：10-12；所述自发热组分为粒径为20至50μm的赭石粉；所述赭石粉与中药组分的质量比为1:3-5。
优选地，所述中药组分的原料药材配方按重量份计为：柴胡10份、白芍15份、香附15份、荔枝核15份、天门冬10份、三棱15份、莪术10份、橘叶15份、丹参10份、半夏10份、牡蛎粉15份。
优选地，按重量份计，所述促渗透组分中泊洛沙姆188为3-5份；所述芒硝为4-10份；所述月桂氮卓酮为1-3份。
优选地，所述赭石粉的粒径为40μm。
本发明的有益效果如下：
本发明所述的具有治疗乳腺增生的自发热中药制剂，可疏肝活血、软坚散结、消肿止痛；用于肝郁气结，气滞血瘀所引起的乳腺增生，乳核结节、胀痛；其组方科学合理，一方面该中药制剂中促渗透组分能进入皮肤角质层，使细胞间脂质排列有序性降低，脂质双分子层的流动性增加，即皮肤穿透性增加，从而提高或加速药物渗透穿过皮肤的物质，与药物及其辅料有良好的相容性，起效快，作用时间长；另一方面，该中药制剂中自发热组分可以自动散发热量，无需额外进行加热，使药效更好的通过皮肤毛孔透皮吸收，并且保温时间较长，能更好的发挥出中药制剂的药性，治疗/理疗效果好。
具体实施方式
为了加深对本发明的理解，下面将结合实施例对本发明作进一步详述，该实施例仅用于解释本发明，并不构成对本发明保护范围的限定。
实施例1
一种具有治疗乳腺增生的自发热中药制剂，按重量份计，由以下组分组成，柴胡5份、白芍10份、香附10份、荔枝核10份、天门冬5份、三棱10份、莪术5份、橘叶10份、丹参5份、半夏5份、牡蛎粉10份；泊洛沙姆188为3份；芒硝为4.5份；月桂氮卓酮为1份；粒径40μm的赭石粉为20份。
实施例2
一种具有治疗乳腺增生的自发热中药制剂，按重量份计，由以下组分组成，柴胡10份、白芍15份、香附15份、荔枝核15份、天门冬10份、三棱15份、莪术10份、橘叶15份、丹参10份、半夏10份、牡蛎粉15份；泊洛沙姆188为4份；芒硝为7份；月桂氮卓酮为2份；粒径40μm的赭石粉为28份。
实施例3
一种具有治疗乳腺增生的自发热中药制剂，按重量份计，由以下组分组成，柴胡15份、白芍20份、香附20份、荔枝核20份、天门冬15份、三棱20份、莪术15份、橘叶20份、丹参15份、半夏15份、牡蛎粉20份；泊洛沙姆188为5份；芒硝为8份；月桂氮卓酮为3份；粒径40μm的赭石粉为68份。
至今累计收治了2000例的患者，经过临床观察，证明本发明对各类乳腺增生病有明显的疗效，而且产生了良好的社会效益，现就可评价的300例患者中疗效总结见下表：
典型病例：
病例1：吴某，女，49岁，职业：售货员，单侧乳房肿块疼痛6个月余，经B超检查为单侧乳腺增生，经前1周乳房疼痛加重。使用本发明中药制剂一个疗程后，肿块明显缩小、疼痛减轻；连续两个疗程后，乳腺增生症状完全消失，身体恢复正常。
病例2：赵某，女，45岁，职业：收银员，双侧乳房肿块疼痛3个月余，随月经周期而加重，经乳腺诊断仪和B超检查诊断为双侧乳腺增生，伴有月经量少、色暗，经前1周乳房疼痛加重。使用本发明中药制剂三个疗程后，肿块消散、疼痛消失，乳腺增生症状完全消失，身体恢复正常。
病例3：刘某，女，49岁，职业：服务员，单侧乳房肿块疼痛2个月余，经B超检查为单侧乳腺增生、乳房结节。使用本发明中药制剂两个半疗程后，结节消散、疼痛消失，乳腺增生症状完全消失，身体恢复正常。
病例4：李某，女，28岁，职业：白领，双侧乳房肿块疼痛3个月余，经检测为：双侧乳腺胀硬，内有多个结块，大小形态不一，大者约2.5cm×2cm×3cm，小者约0.2cm×0.5cm×0.5cm，使用本发明中药制剂半个半疗程后，嘱其饮食、情志自我调护，复诊时，两乳松软，局部、肩臂疼痛基本消失，肿块明显减少及缩小，继续用药3个疗程，肿块症状全部消失，精神愉悦，心情舒畅，随访1年无复发。
以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。

Claims (4)

1.一种具有治疗乳腺增生的自发热中药制剂，其特征在于，包括中药组分、促渗透组分和自发热组分；所述中药组分的原料药材配方按重量份计，柴胡5-15份、白芍10-20份、香附10-20份、荔枝核10-20份、天门冬5-15份、三棱10-20份、莪术5-15份、橘叶10-20份、丹参5-15份、半夏5-15份和牡蛎粉10-20份；所述促渗透组分由泊洛沙姆188、芒硝和月桂氮卓酮的组成；所述促渗透组分与中药组分的质量比为1：10-12；所述自发热组分为粒径为20至50μm的赭石粉；所述赭石粉与中药组分的质量比为1:3-5。
2.根据权利要求书1所述的一种具有治疗乳腺增生的自发热中药制剂，其特征在于，所述中药组分的原料药材配方按重量份计为：柴胡10份、白芍15份、香附15份、荔枝核15份、天门冬10份、三棱15份、莪术10份、橘叶15份、丹参10份、半夏10份和牡蛎粉15份。
3.根据权利要求书1所述的一种具有治疗乳腺增生的自发热中药制剂，其特征在于，按重量份计，所述促渗透组分中泊洛沙姆188为3-5份；所述芒硝为4-10份；所述月桂氮卓酮为1-3份。
4.根据权利要求书1所述的一种具有治疗乳腺增生的自发热中药制剂，其特征在于，所述赭石粉的粒径为40μm。
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