CN110237171A - A kind of pharmaceutical composition for caput femoris necrosis and preparation method thereof and purposes - Google Patents
A kind of pharmaceutical composition for caput femoris necrosis and preparation method thereof and purposes Download PDFInfo
- Publication number
- CN110237171A CN110237171A CN201910551403.8A CN201910551403A CN110237171A CN 110237171 A CN110237171 A CN 110237171A CN 201910551403 A CN201910551403 A CN 201910551403A CN 110237171 A CN110237171 A CN 110237171A
- Authority
- CN
- China
- Prior art keywords
- parts
- preparation
- pharmaceutical composition
- caput femoris
- femoris necrosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Insects & Arthropods (AREA)
- Rheumatology (AREA)
- Animal Husbandry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of pharmaceutical composition for caput femoris necrosis and preparation method thereof and purposes, its raw material includes: 20~30 parts of Radix Astragali, 3~10 parts of ginseng, 3~5 parts of deer horn, 10~15 parts of Radix Angelicae Sinensis, 10~15 parts of honeysuckle, 10~20 parts of oldenlandia diffusa, 10~15 parts of Cortex Phellodendri, 10~15 parts of rhizoma anemarrhenae, 10~15 parts of the root bark of Chinese wolf-berry, 10~20 parts of Poria cocos, 10~15 parts of radix achyranthis bidentatae, 5~10 parts of Rhizoma Chuanxiong, 10~20 parts of rhizoma corydalis, 10~20 parts of ground bettle, 5~10 parts of pheretima, 10~20 parts of turtle shell, 10~15 parts of rhizoma cyperi, 3~7 parts of aconiti preparata,radix, 5~10 parts of olibanum, 5~10 parts of myrrh.The present invention also provides the preparation method of the composition and purposes.The composition is used to prepare the oral preparation for the treatment of caput femoris necrosis.The present invention has the characteristics that few reasonable recipe, dosage, significant effect, has no toxic side effect, and can effectively cure caput femoris necrosis.
Description
Technical field
The present invention relates to pharmaceutical composition of a kind of traditional Chinese medicine formulation art and preparation method thereof and purposes, specifically,
It is related to a kind of pharmaceutical composition for caput femoris necrosis and preparation method thereof and purposes.
Background technique
Caput femoris necrosis is the lesion as caused by hip joint traumatic injury, and caput femoris necrosis is a Pathologic process,
Initially occur in the weight bearing area of femoral head, under stress necrotic bone trabecular bone structure occur damage i.e. it is micro- fracture and then
For the repair process of injured bone, the reason of causing osteonecrosis, is not eliminated, repair it is not perfect, damage-reparation process after
The reasons such as continuous, lead to the change of femur header structure, collapse of femoral head, deformation, arthritis, dysfunction.Serious person finally needs
It is remedied by artificial hip joint replacing, walking ability could be restored.
Chinese medicine thinks: the disease is deep damp and hot erosion of having a cold, and exopathogen is penetrated into and caused, joint fever, swelling pressuring nerve
Pain, difficulty in walking, joint stuffiness, continuous low fever, it is difficult to cure due to insufficiency of primordial QI, immunity degradation, caused by liver and kidney deficiency, wind
Cold-dampness heresy invades bone network, influences QI-blood circulation, leads to stagnation of QI-blood, and operation is lost smooth, and then cartilage is destroyed, blockage of main and collateral channels and
Bitterly.Principle is clear, logical, tune, benefit in the treatment, it is desirable to which healing then mainly needs to improve immune function, to reach elimination femur
The difficult disease of necrosis.
Summary of the invention
The object of the present invention is to provide a kind of pharmaceutical composition and preparation method thereof and purposes, bad for femoral head by this
The dedicated Oral preparation of dead herbal mixture, is able to solve existing issue, also has that reasonable recipe, dosage be few, significant effect, nontoxic pair
The features such as effect.
In order to achieve the above object, the present invention provides a kind of pharmaceutical compositions for caput femoris necrosis, wherein the group
The raw material for closing object includes: Radix Astragali, ginseng, deer horn, Radix Angelicae Sinensis, honeysuckle, oldenlandia diffusa, Cortex Phellodendri, rhizoma anemarrhenae, the root bark of Chinese wolf-berry, Poria cocos, ox
Knee, Rhizoma Chuanxiong, rhizoma corydalis, ground bettle, pheretima, turtle shell, rhizoma cyperi, aconiti preparata,radix, olibanum, myrrh.
The above-mentioned pharmaceutical composition for caput femoris necrosis, wherein the composition includes according to parts by weight: yellow
20~30 parts of stilbene, 3~10 parts of ginseng, 3~5 parts of deer horn, 10~15 parts of Radix Angelicae Sinensis, 10~15 parts of honeysuckle, oldenlandia diffusa 10~
20 parts, 10~15 parts of Cortex Phellodendri, 10~15 parts of rhizoma anemarrhenae, 10~15 parts of the root bark of Chinese wolf-berry, 10~20 parts of Poria cocos, 10~15 parts of radix achyranthis bidentatae, Rhizoma Chuanxiong 5
~10 parts, 10~20 parts of rhizoma corydalis, 10~20 parts of ground bettle, 5~10 parts of pheretima, 10~20 parts of turtle shell, 10~15 parts of rhizoma cyperi, system
3~7 parts of monkshood, 5~10 parts of olibanum, 5~10 parts of myrrh.
The above-mentioned pharmaceutical composition for caput femoris necrosis, wherein the composition includes according to parts by weight: yellow
25 parts of stilbene, 7 parts of ginseng, 4 parts of deer horn, 12 parts of Radix Angelicae Sinensis, 13 parts of honeysuckle, 15 parts of oldenlandia diffusa, 13 parts of Cortex Phellodendri, 12 parts of rhizoma anemarrhenae,
12 parts of the root bark of Chinese wolf-berry, 15 parts of Poria cocos, 13 parts of radix achyranthis bidentatae, 8 parts of Rhizoma Chuanxiong, 15 parts of rhizoma corydalis, 15 parts of ground bettle, 7 parts of pheretima, 15 parts of turtle shell,
12 parts of rhizoma cyperi, 5 parts of aconiti preparata,radix, 8 parts of olibanum, 7 parts of myrrh.
The present invention also provides the preparation methods of the above-mentioned pharmaceutical composition for caput femoris necrosis, wherein described
Method are as follows: weigh each medicine material in proportion, clean respectively and grind broken, then will grind broken all drugs and be put into
Mixing, is soaked in water in container, is reheated and is decocted, then filter and remove residue obtains medical fluid, is finally cooled down.
The preparation method of the above-mentioned pharmaceutical composition for caput femoris necrosis, wherein in the method, grinding is broken
Particle size range be 30~40 mesh.
The preparation method of the above-mentioned pharmaceutical composition for caput femoris necrosis, wherein in the method, grinding is broken
All drugs after broken are put into porcelain jar, and 8~12 times of drug total amount by weight of distillation water cover is added and crosses drug, impregnates 20
~40min.
The preparation method of the above-mentioned pharmaceutical composition for caput femoris necrosis, wherein in the method, heating is decocted
It is first to be fried open medical fluid with high fire, then with ceasing fire after being cooked by slow fire 30~60min, pours out and filtering liquid medicine, again by the dregs of a decoction filtered out
It pours into porcelain jar and adds water to cook.
The preparation method of the above-mentioned pharmaceutical composition for caput femoris necrosis, wherein in the method, by what is filtered out
The dregs of a decoction pour into porcelain jar again, and 6~8 times of drug total amount by weight of distilled water is added, is fried open medical fluid with high fire, then use mild fire
20~40min is decocted, medical fluid is poured out in filtering, and is mixed with resulting medical fluid for the first time.
Present invention provides the purposes of the pharmaceutical composition of above-mentioned method preparation, wherein the composition is used for
The oral preparation of preparation treatment caput femoris necrosis.
The purposes of the pharmaceutical composition for caput femoris necrosis of above-mentioned method preparation, wherein the oral preparation
In one after each meal, daily 2~3 times, each taking 200~300ml, 1 month as a treatment course.
Pharmaceutical composition provided by the present invention for caput femoris necrosis and preparation method thereof and having for purposes are following excellent
Point:
The present invention is to provide a kind of radical cure femur necrosis, bones to go rotten, and specially controls the dedicated decoction of heumatism, reasonable by suiting the medicine to the illness
Drug quality part ratio, in conjunction with the clinical experience of the disease of the mildew and rot difficulty of effective treatment caput femoris necrosis, bone, obtained by research arranges
The practical technical solution of a set of innovation.
The present invention in the heumatism difficult and complicated cases for the treatment of femur necrosis, is led to the continuous development of China's traditional Chinese medicine and pharmacy
Proved recipe clinic raw medicine is crossed newly to use, constantly understanding demonstrates we and is being used for the mildew and rot aspect of caput femoris necrosis, bone in application process,
, the advantages such as toxic side effect small excellent, quick with curative effect spy, can cure bone and joint diseases.
Composition provided by the present invention, while there is reasonable recipe, pure natural no added, the nontoxic secondary work of animals and plants draft
With, not wound body the features such as, hence it is evident that better than the drug of similar functions.
Specific embodiment
A specific embodiment of the invention is further described below.
Provided by the present invention for the pharmaceutical composition of caput femoris necrosis, the raw material of the composition includes: Radix Astragali, ginseng,
Deer horn, Radix Angelicae Sinensis, honeysuckle, oldenlandia diffusa, Cortex Phellodendri, rhizoma anemarrhenae, the root bark of Chinese wolf-berry, Poria cocos, radix achyranthis bidentatae, Rhizoma Chuanxiong, rhizoma corydalis, ground bettle, ground
Dragon, turtle shell, rhizoma cyperi, aconiti preparata,radix, olibanum, myrrh.
Preferably, the composition includes according to parts by weight: 20~30 parts of Radix Astragali, 3~10 parts of ginseng, and 3~5 parts of deer horn,
10~15 parts of Radix Angelicae Sinensis, 10~15 parts of honeysuckle, 10~20 parts of oldenlandia diffusa, 10~15 parts of Cortex Phellodendri, 10~15 parts of rhizoma anemarrhenae, ground bone
10~15 parts of skin, 10~20 parts of Poria cocos, 10~15 parts of radix achyranthis bidentatae, 5~10 parts of Rhizoma Chuanxiong, 10~20 parts of rhizoma corydalis, ground bettle 10~20
Part, 5~10 parts of pheretima, 10~20 parts of turtle shell, 10~15 parts of rhizoma cyperi, 3~7 parts of aconiti preparata,radix, 5~10 parts of olibanum, myrrh 5~10
Part.
It is highly preferred that the composition includes according to parts by weight: 25 parts of Radix Astragali, 7 parts of ginseng, 4 parts of deer horn, 12 parts of Radix Angelicae Sinensis,
13 parts of honeysuckle, 15 parts of oldenlandia diffusa, 13 parts of Cortex Phellodendri, 12 parts of rhizoma anemarrhenae, 12 parts of the root bark of Chinese wolf-berry, 15 parts of Poria cocos, 13 parts of radix achyranthis bidentatae, Rhizoma Chuanxiong
8 parts, 15 parts of rhizoma corydalis, 15 parts of ground bettle, 7 parts of pheretima, 15 parts of turtle shell, 12 parts of rhizoma cyperi, 5 parts of aconiti preparata,radix, 8 parts of olibanum, myrrh 7
Part.
Wherein, Radix Astragali nature and flavor are sweet, warm, return lung, the spleen channel.Invigorating qi for strengthening superficies is cured mainly, strengthening spleen and middle warmer is bowl spares gas key medicine, application
Spleen, the kidney qi chronic diseases marked by deficiency of vital energy and all diseases of the sinking of qi of middle-jiao, yang invigorating, Lung Qi deficiency disease, invigorating qi for consolidating superficies, kidney qi deficiency disease of spontaneous perspiration, eliminating toxic is raw new, gas
The deficiency of blood, deficiency of vital energy water-wet lose the oedema of fortune, difficult urination.
Ginseng nature and flavor are sweet, slight bitter, micro- wet, return lung, spleen, the heart channel of Hang-Shaoyin.Cure mainly reinforce vital energy, vigour collapse card, tonifying lung benefit lung, lung
Spleen heart syndrome of deficiency of kidney qi, promotes the production of body fluid to quench thirst, the pyreticosis deficiency of vital energy, injury thirst and diabetes, tranquilize the mind and promote the intelligence, the palpitaition of blood deficiency, insomnia,
Amnesia etc..Muscles and bones, adjust total punching to appoint, kidney deficiency bone it is weak, waist-leg weakness or children's five kinds of retardation and women's cold and deficiency of chong and ren channels, metrorrhagia and metrostaxis leukorrhagia, eliminating toxic,
Sore burst for a long time and does not holds back, negative subcutaneous ulcer sore swells can not invaginated.
Deer horn nature and flavor are sweet, it is salty, warm, return kidney, Liver Channel.Cure mainly kidney-replenishing, benefiting essence-blood, decline of kidney-YANG, asthenia of essence and blood disease, strengthening tendons
Strong bone.
Radix Angelicae Sinensis nature and flavor are sweet, it is close, warm, return liver, the heart, the spleen channel, tonifying blood and regulating menstruation, for the panacea enriched blood.Cure mainly all cards of the deficiency of blood, promoting blood circulation
It relieves pain, the irregular menstruation of blood deficiency and blood stasis, amenorrhoea, dysmenorrhea, deficient cold type abdominal pain, traumatic injury, pain subcutaneous ulcer sore, chill numbness pain etc., profit
Intestines defaecation, deficiency of blood dry constipation of intestines.
Honeysuckle is caprifoliaceae plant honeysuckle, lonicera hypoglauca miq, Honeysuckle flower or the dry flower of hair style honeysuckle or with just opening
Flower.Nature and flavor are sweet, tremble with fear;Return lung, the heart, stomach meridian.With clearing heat and detoxicating, dispelling wind and heat from the body effect.Cure mainly carbuncle swells furunculosis, affection of exogenous wind-heat,
Warm disease is from the beginning of toxic-heat and blood stasis.
Oldenlandia diffusa is the herb of Rubiaceae plants of Hedyotis oldenlandia diffusa.It is bitter in taste, sweet, it trembles with fear;Enter stomach, large intestine,
Small intestinl channel.With clearing heat and detoxicating, carbuncle that disappears dissipating bind, effect that promoting urination and removing dampness, dampness removing are treating stranguria.For carbuncle sore tumefacting virus, abscess of throat, poison
Snake bite, puckery pain of heat gonorrhea, various tumours, damp and hot oedema, jaundice, acute appendicitis, pulmonary abscess, boil.
Cortex Phellodendri is the dry bark of rutaceae wampee, and bitter is cold in nature, returns kidney, bladder meridian, has heat-clearing dry
It is wet, the effect of purging intense heat, except steaming, detoxification sore treatment, it is used for damp-heat dysentery, jaundice and reddish urine, leukorrhagia pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence is preesed,
Hectic fever due to yin labor heat, night sweat, spermatorrhea, sore swollen toxin, eczema wet sore;Stir-baked CORTEX PHELLODENDRI with salt solution nourishing yin and lessening fire;For fire excess from yin deficiency, night sweat hectic fever due to yin.
Rhizoma anemarrhenae is the dry rhizome of monocotyledon Liliaceae rhizoma anemarrhenae.There is cultivation all over China, main producing region is in river
North.Palpus and silt or crust are removed, is dried, slice is used as medicine.It is bitter in taste, it trembles with fear.Return lung, stomach, kidney channel.Effect is clearing heat-fire, is grown
Yin is moisturized.Cure mainly pyreticosis and polydipsia, lung-heat type cough, osteopyrexia and fever, Heat Diabetes, dry constipation of intestines.
Root bark of Chinese wolf-berry alias Chinese wolfberry skin is Solanaceae, the root skin of Lycium fructus lycii.Bitter cold is respectful clearly, directly enters lower burnt liver kidney.Tool
Have and bring down a fever except steaming, the benefits of heat-clearing, cool blood, cool blood except steam, clearing lung-heat fall fire, cure mainly consumptive disease hectic fever night sweat, lung heat cough and asthma is spitted blood, nosebleed
Blood, blood strangury are quenched one's thirst, hypertension, carbuncle swells, malignant sore.
Poria cocos is the dry sclerotia of polyporaceae fungus.It is excavated more than 7~September, removes silt after digging out, bank up
It after " sweating ", spreads out and dries in the air to dry tack free, then " sweating ", be repeated several times to existing wrinkle, the big portion of internal moisture after scattering and disappearing, dry in the shade,
Referred to as " Poria cocos ";Or fresh Poria cocos is pressed into different parts cutting, it dries in the shade, is referred to as " Poria cocos block " and " Indian buead tablet ".Sweet in flavor,
It is light, mild-natured, return heart, lung, spleen, kidney channel.Have effects that clearing damp and promoting diuresis, invigorating the spleen, calming heart.Cure mainly edema and little urine, phlegm retention anti-dazzle nervous, spleen
Empty deficiency of food, loose stool diarrhea, confused and worried, insomnia of palpitating with fear etc., can be used for Energy benefit taste.
Radix achyranthis bidentatae is Amaranthaceae, Achyranthes herbaceos perennial.Dry root is used as medicine, raw to use.It is bitter in taste, sweet, sour, it puts down.Return liver,
Kidney channel.Effect is dispelling stasis of blood and stimulating the menstrual flow, nourishing liver and kidney, strengthening the bones and muscles, and inducing diuresis for treating strangurtia is ensuringd proper downward flow of the blood.For menostasis, dysmenorrhea, soreness of waist and knee joint, muscle
Bone is powerless, stranguria, oedema, headache, dizziness toothache, day sore, spit blood, bleeding from five sense organs or subcutaneous tissue.
Rhizoma Chuanxiong is the dry rhizome of umbelliferae Rhizoma Chuanxiong;Excavation in May, removes silt, stoving after sun drying, then remove fibrous root.With
When slice is raw uses or wine toast.Nature and flavor are acrid in flavour and warm in nature;Return liver, gallbladder, pericardium channel;Effect is promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain;It is main
Control air-cooled headache and dizziness, hypochondriac pain abdomen pain, arthritis muscle contraction, menostasis, difficult labour, postpartum stasis block pain, ulcer sores.Not for menstruation
Tune, amenorrhea and algomenorrhea, lump in the abdomen abdominal pain, pricking pain in the chest, tumbling and swelling, headache, rheumatic arthralgia.
Rhizoma corydalis nature and flavor acrid, bitter, warm, returns liver, spleen, the heart channel of Hang-Shaoyin.Cure mainly activating microcirculation and removing stasis medicinal, promoting qi circulation and relieving pain." stagnation of the circulation of vital energy in promoting circulation of blood ",
Stasis in gas, thus with capable of specially controlling under all pains, mainly control the stagnant pain of the stasis of blood, no matter which kind of pain can briefly adapted it.
Ground bettle is the female adult hirudo leech of Corydiidae eupolyphagasinensis walker or polyphagaplancyi.Wild survivor's summer captures;Raiser is annual
It can capture.It is scalded extremely with boiling water, dries or dry.Nature and flavor are salty, tremble with fear;Return liver warp.With dissipating blood stasis with potent drugs, the effect of reunion of fractured tendons and bones.It is main
Control traumatic injury, injury of tendon and muscle fracture, pain caused by ecchymoma, blood stasis, postpartum stasis abdominal pain, accumulation lump in the abdomen.
Pheretima, that is, earthworm, removes impurity, dry.Have effects that heat-clearing arresting convulsion, dredging collateral, relieving asthma, diuresis.Normal frying
Afterwards for diseases such as high fever, coma, twitch, arthralgia, dyspnea and cough due to lung-heat, oliguria oedema, hypertension.
Turtle shell is the carapace of cyprinidae.Nature and flavor are sweet, it is salty, tremble with fear, return liver and kidney channel.With nourishing and suppressing Yang, bring down a fever except steaming,
The effect of resolving hard lump.It is usually used in fever due to yin deficiency, hectic fever due to yin labor heat, hyperactivity of yang due to yin deficiency is had a dizzy spell, endogenous deficient wind, menostasis , Disorder lump in the abdomen,
Chronic malaria malaria with abdominal mass.
Rhizoma cyperi nature and flavor are pungent, slight bitter, slight bitter, put down, and return liver, spleen, two burnt warps.Soothing liver-qi stagnation is cured mainly, is stopped for soothing liver-qi stagnation promoting the circulation of qi
The key medicine of pain, menstruction regulating and pain relieving gynaecology key medicine, in qi-regulating tune, taste stagnation of the circulation of vital energy disease.
Aconiti preparata,radix is the Preparation process product of monkshood.Acrid flavour, hardship, property heat.The heart, liver,kidney,spleen warp.With dispelling wind and eliminating dampness, Wen Jing
The effect of analgesic.It is used for treating arthralgia due to cold and dampness, joint crymodynia, cold hernia is had a pain and narcotic analgesic.
Olibanum nature and flavor are pungent, bitter, tepor, have the effect of blood-activating and qi-promoting, inducing meastruation to relieve menalgia, detumescence and promoting granulation, for treating trusted subordinate
The diseases such as pain, rheumatic arthralgia, amenorrhea and algomenorrhea, bruise stasis caused pain, swollen ulcer drug, enterodynia, unhealing ulcer, ruptured abscess resistant to healing.
Myrrh is bitter in taste, flat, has the effect of promoting blood circulation and stopping pain, detumescence and promoting granulation, for treat chest and abdomen stasis caused pain, dysmenorrhoea, menostasis,
The diseases such as disease, lump in the abdomen, traumatic injury, carbuncle swells sore acute appendicitis, red eye, swell pain.
The present invention also provides the preparation method of the pharmaceutical composition for caput femoris necrosis, this method are as follows: in proportion
Each medicine material is weighed, clean respectively and is ground broken, then will grind broken all drugs and be put into container and mix, add
Water impregnates, and reheats and decocts, then filter and remove residue obtains medical fluid, is finally cooled down.
Preferably, grinding broken particle size range is 30~40 mesh.
Broken all drugs will be ground to be put into porcelain jar, 8~12 times of drug total amount by weight of distillation is added
Water cover crosses drug, impregnates 20~40min, preferably 30min.
It is first to be fried open medical fluid with high fire that heating, which decocts, then with ceasing fire after 30~60min of mild fire (small fire) decoction, is poured out and mistake
Medical fluid is filtered, the dregs of a decoction filtered out are poured into porcelain jar again and are added water to cook.
The dregs of a decoction filtered out are poured into porcelain jar again, 6~8 times of drug total amount by weight of distilled water is added, uses high fire
Be fried open medical fluid, then with being cooked by slow fire 20~40min, preferably 30min, medical fluid is poured out in filtering, and with resulting medical fluid for the first time
Mixing.
Present invention provides the purposes of the pharmaceutical composition of this method preparation, the composition is used to prepare treatment femoral head
The oral preparation of necrosis.
The oral preparation is in one after each meal, and daily 2~3 times, each taking 200~300ml, 1 month as a treatment course.
Slight 1~3 course for the treatment of is cured, and 3~6 course for the treatment of of severe is cured.
Below with reference to embodiment to pharmaceutical composition provided by the present invention for caput femoris necrosis and preparation method thereof with
Purposes is further described.
Examples 1 to 4
The pharmaceutical composition for caput femoris necrosis of material composition proportion preparation shown in each embodiment difference according to the form below 1
Object.Each raw material corresponds with corresponding national standard.
List of ingredients (according to parts by weight) of the table 1. for the pharmaceutical composition of caput femoris necrosis.
Various embodiments of the present invention additionally provide the preparation method of the pharmaceutical composition for being used for caput femoris necrosis, and system
The purposes of standby composition.
This method are as follows: weigh each medicine material in proportion, clean respectively and grind broken, grinding broken particle size range is
30~40 mesh.Then it broken all drugs will be ground is put into container such as porcelain jar and mix, it is total that drug by weight is added
The distillation water cover of 8~12 times of amount crosses drug, impregnates 20~40min.It reheats and decocts, be first fried open medical fluid with high fire, then use mild fire
(small fire) ceases fire after decocting 30~60min, pours out simultaneously filtering liquid medicine, the dregs of a decoction filtered out are poured into porcelain jar again, be added by weight
It is calculated as 6~8 times of drug total amount of distilled water, is fried open medical fluid with high fire, then with 20~40min is cooked by slow fire, medical fluid is poured out in filtering,
And mixed with resulting medical fluid for the first time, finally cooled down.
Various embodiments of the present invention also provide the purposes of the composition of this method preparation, and the composition is used to prepare treatment
The oral preparation of caput femoris necrosis.
The oral preparation is in one after each meal, and daily 2~3 times, each taking 200~300ml, 1 month as a treatment course.
Slight 1~3 course for the treatment of is cured, and 3~6 course for the treatment of of severe is cured.
The common adverse reactions for being used for the pharmaceutical composition of caput femoris necrosis have dry, palpitaition, slight upset,gastro-intestinal, stop
It can disappear after medicine.Points for attention are as follows when taking: 1, can not excess take this prescription Chinese materia medica preparation, Ying Shenyong;2, serious stomach
Ulcers avoid clothes;3, pregnant woman disables;4, forbid excessive use or adverse reaction occur, doctor or pharmacist is asked to see a doctor immediately;5,
Children prohibit clothes, and hepatic and kidney function obstacle person prohibits clothes.
Externally applied formulation is made using composition prepared by each embodiment, and parting has been carried out to over one hundred patient at random
Diagnosis and treatment based on an overall analysis of the illness and the patient's condition clinical test is taken medicine patient 150, and less serious case takes 1~3 course for the treatment of, and severe one takes 3~6 courses for the treatment of, cures 120 altogether,
Separately have 28 effectively, it is efficient up to 98% or more wherein 24 are being continued to cure for medication 1 month, cure rate reach 96% with
On.
Typical case 1: square XX, female, 42 years old, people from Xiushui county Jiangxi province, right hip joint fever pain, difficulty in walking, through Nanchang
Hospital looks into category caput femoris necrosis, need to perform an operation, after transfer from one hospital to another hospitals of Shanghai, indagation also belongs to femur necrosis, need to perform an operation.After toss about
Carry out here consulting, after having used 10 doses of Chinese medicines provided by the invention, improve, fever is reduced, and pain mitigates, after continuing medication 3 months, no
Bitterly, it does not generate heat, movable function is normal, consolidates medication 1 month, and normal, follow-up after half a year is looked into through Nanchang hospital, has no multiple
Hair.
Typical case 2: leaf XX, female, 54 years old, Jiangxi Province people from Wuning County, legs and feet enlargement, hard swelling, light tenderness, skin, which black, to be sent out
It is bright, the bottom of s trouser leg wear not into, it is in great pain, cannot walk.Reason is accidentally to fall when dish is plucked in vegetable plot in the country, and left thigh bone falls
It is disconnected, it send to hospital and makes film, check that fracture, bone within bone network turn black entirely, treat synthetism, Interal fixation through institute, left hospital more than 1 moon, more than 3
Left leg is caused to swell and ache after month, local medical therapy is improper, Nanchang hospital of transferring from one hospital to another, invalid through half remaining moon treatment, it is proposed that patient
Perform an operation and (cut off left limb), patient be unwilling to, it is rear to toss about to come Ben Chu, use Chinese materia medica preparation provided by the invention, process are as follows: 1, in
Medicine fumigation totally 10 times;2, oral traditional Chinese medicine, the combination of inner and outside, pain is substantially reduced after three days, and after two weeks, red and swollen pain all improves, and continues
It takes traditional Chinese medicine, is cured substantially after three months, walking is normal, and follow-up after 1 year is not recurred.
Pharmaceutical composition for caput femoris necrosis of the invention is to follow traditional Chinese medical theory when in use, first with four
It examines and (hopes, hears, asking, cutting) and doctor trained in Western medicine chemical examination, X-ray is combined to divide monarch according to patient age, constitution medication for foundation, minister, a left side, make,
Shield help tying-in drug compatible, reasonable utilization lifting sink-float channel tropism application, sort out it is a kind of treat femur necrosis, bone go rotten
Dedicated decoction.
As follows using side's solution: it is monarch that Radix Astragali and ginseng are reused in side, is for tonifying Qi panacea, with Rhizoma Chuanxiong, (Rhizoma Chuanxiong is gas in blood
Medicine) to building up healthful vital energy, it commands all medicines and goes directly lesion, exempt from numbness except stagnant, add honeysuckle, oldenlandia diffusa, Chilly thermal detoxification, with Huang
Cypress, rhizoma anemarrhenae, the root bark of Chinese wolf-berry, Poria cocos dispelling deficient fire diuresis, play the role of up and down balance system, add monkshood except wet ecchymosis in bone, ground bettle,
Imperial energy degrading the channel, recovers injured nerve;Radix Angelicae Sinensis, radix achyranthis bidentatae, rhizoma corydalis, activating microcirculation and removing stasis medicinal are kind to control recuperating qi-blood, joint joint stuffiness;
Pilose antler turtle shell, tonifying both YIN and YANG match rhizoma cyperi qi-regulating.Comprehensive we, qi and blood improve hot and humid ecchymosis, the fire of deficiency type inside and outside clear bone and can remove, kidney tonifying
Strong bone can recover necrotic bone nerve.Our all medicines share, plays strengthening vital QI to eliminate pathogenic factors altogether, and degrading the channel, saprophytic removing can cure femoral head
The effect of downright bad rehabilitation.
Pharmaceutical composition provided by the present invention for caput femoris necrosis and preparation method thereof and purposes, for the disease of disease
Because of the interpretation of the cause, onset and process of an illness, using the complementary compatibility principle of drug, purposefully all medicines are rationally matched by monarch, institutional framework minister, helped, made
5, the drug and its compatibility and the interpretation of the cause, onset and process of an illness of disease in the side of making are intricately woven together, the vertical therapy of aggreggate utility and institute after making compatibility of drugs
High unity.The composition is to have passed through the clinical test of many cases, to the function of its every herbal medicine and is cured mainly and according to the modern times
A kind of prescription of the pharmacological research of traditional Chinese and western medicine and formation, with formula is scientific and reasonable, production method is simple and easy, easy to spread
The characteristics of, caput femoris necrosis can be effectively eradicated, and have no adverse reaction and side effect.
It is discussed in detail although the contents of the present invention have passed through above preferred embodiment, but it should be appreciated that above-mentioned
Description is not considered as limitation of the present invention.After those skilled in the art have read above content, for of the invention
A variety of modifications and substitutions all will be apparent.Therefore, protection scope of the present invention should be limited to the appended claims.
Claims (10)
1. a kind of pharmaceutical composition for caput femoris necrosis, which is characterized in that the raw material of the composition includes:
Radix Astragali, ginseng, deer horn, Radix Angelicae Sinensis, honeysuckle, oldenlandia diffusa, Cortex Phellodendri, rhizoma anemarrhenae, the root bark of Chinese wolf-berry, Poria cocos, radix achyranthis bidentatae, Rhizoma Chuanxiong prolong
Hu Suo, ground bettle, pheretima, turtle shell, rhizoma cyperi, aconiti preparata,radix, olibanum, myrrh.
2. being used for the pharmaceutical composition of caput femoris necrosis as described in claim 1, which is characterized in that the composition is by weight
Amount number meter includes:
20~30 parts of Radix Astragali, 3~10 parts of ginseng, 3~5 parts of deer horn, 10~15 parts of Radix Angelicae Sinensis, 10~15 parts of honeysuckle, oldenlandia
10~20 parts of grass, 10~15 parts of Cortex Phellodendri, 10~15 parts of rhizoma anemarrhenae, 10~15 parts of the root bark of Chinese wolf-berry, 10~20 parts of Poria cocos, radix achyranthis bidentatae 10~15
Part, 5~10 parts of Rhizoma Chuanxiong, 10~20 parts of rhizoma corydalis, 10~20 parts of ground bettle, 5~10 parts of pheretima, 10~20 parts of turtle shell, rhizoma cyperi 10
~15 parts, 3~7 parts of aconiti preparata,radix, 5~10 parts of olibanum, 5~10 parts of myrrh.
3. being used for the pharmaceutical composition of caput femoris necrosis as claimed in claim 2, which is characterized in that the composition is by weight
Amount number meter includes:
25 parts of Radix Astragali, 7 parts of ginseng, 4 parts of deer horn, 12 parts of Radix Angelicae Sinensis, 13 parts of honeysuckle, 15 parts of oldenlandia diffusa, 13 parts of Cortex Phellodendri, rhizoma anemarrhenae
12 parts, 12 parts of the root bark of Chinese wolf-berry, 15 parts of Poria cocos, 13 parts of radix achyranthis bidentatae, 8 parts of Rhizoma Chuanxiong, 15 parts of rhizoma corydalis, 15 parts of ground bettle, 7 parts of pheretima, turtle shell
15 parts, 12 parts of rhizoma cyperi, 5 parts of aconiti preparata,radix, 8 parts of olibanum, 7 parts of myrrh.
4. a kind of preparation method of the pharmaceutical composition for caput femoris necrosis as described in any one of claims 1 to 3,
It is characterized in that, the method are as follows: weigh each medicine material in proportion, clean respectively and grind it is broken, then will grinding it is broken
All drugs after broken are put into mixing in container, soak in water, and reheat and decoct, then filter and remove residue obtains medical fluid, most laggard
Row cooling.
5. the preparation method for the pharmaceutical composition of caput femoris necrosis as claimed in claim 4, which is characterized in that described
It is 30~40 mesh that broken particle size range is ground in method.
6. the preparation method for the pharmaceutical composition of caput femoris necrosis as claimed in claim 4, which is characterized in that described
In method, broken all drugs will be ground and be put into porcelain jar, 8~12 times of drug total amount by weight of distilled water is added
Drug was covered, 20~40min is impregnated.
7. the preparation method for the pharmaceutical composition of caput femoris necrosis as claimed in claim 4, which is characterized in that described
In method, it is first to be fried open medical fluid with high fire that heating, which decocts, then with ceasing fire after being cooked by slow fire 30~60min, is poured out and filtering liquid medicine,
The dregs of a decoction filtered out are poured into porcelain jar again and are added water to cook.
8. the preparation method for the pharmaceutical composition of caput femoris necrosis as claimed in claim 7, which is characterized in that described
In method, the dregs of a decoction filtered out are poured into porcelain jar again, 6~8 times of drug total amount by weight of distilled water is added, decocted with high fire
It writes a prescription liquid, then with 20~40min is cooked by slow fire, medical fluid is poured out in filtering, and is mixed with resulting medical fluid for the first time.
9. a kind of purposes of the pharmaceutical composition of method as claimed in claim 4 preparation, which is characterized in that the composition
It is used to prepare the oral preparation for the treatment of caput femoris necrosis.
10. the purposes of the pharmaceutical composition for caput femoris necrosis of method preparation as claimed in claim 9, feature exist
In the oral preparation is in one after each meal, and daily 2~3 times, each taking 200~300ml, 1 month as a treatment course.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910551403.8A CN110237171B (en) | 2019-06-24 | 2019-06-24 | Medicine composition for femoral head necrosis and preparation method and application thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910551403.8A CN110237171B (en) | 2019-06-24 | 2019-06-24 | Medicine composition for femoral head necrosis and preparation method and application thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110237171A true CN110237171A (en) | 2019-09-17 |
CN110237171B CN110237171B (en) | 2022-02-11 |
Family
ID=67889361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910551403.8A Active CN110237171B (en) | 2019-06-24 | 2019-06-24 | Medicine composition for femoral head necrosis and preparation method and application thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN110237171B (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1319414A (en) * | 2001-01-19 | 2001-10-31 | 刘军 | Medicine for treating hecrosis of femoral head |
CN105456947A (en) * | 2016-01-08 | 2016-04-06 | 青岛市市立医院 | Pharmaceutical composition for treating avascular necrosis of femoral head and application thereof |
-
2019
- 2019-06-24 CN CN201910551403.8A patent/CN110237171B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1319414A (en) * | 2001-01-19 | 2001-10-31 | 刘军 | Medicine for treating hecrosis of femoral head |
CN105456947A (en) * | 2016-01-08 | 2016-04-06 | 青岛市市立医院 | Pharmaceutical composition for treating avascular necrosis of femoral head and application thereof |
Non-Patent Citations (1)
Title |
---|
王庆芳: "《王庆芳中医临证精选》", 31 January 2018 * |
Also Published As
Publication number | Publication date |
---|---|
CN110237171B (en) | 2022-02-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102688452B (en) | Chinese medicinal plaster for treating alcohol-induced osteonecrosis, and preparation method and application thereof | |
CN101700383B (en) | Traditional Chinese medicine for curing ovarian cysts | |
CN101284105A (en) | Thrombolysis lipid-lowering pellet for curing cardio-cerebrovascular disease | |
CN102657835B (en) | Composition and medical liquor for treatment of high blood pressure/rheumatoid arthritis and preparation method and application of composition and medical liquor | |
CN106421649A (en) | Traditional Chinese medicine composition for treating cerebral apoplexy and preparation method thereof | |
CN103893738B (en) | A kind of suppression tumor growth Chinese medicine composition and preparation method thereof | |
CN104984265A (en) | Traditional Chinese medicine preparation for cutaneous hemangioma and preparation method thereof | |
CN104906507A (en) | Traditional Chinese medicine combination for lowering blood pressure and toning physical fitness | |
CN104740211A (en) | Traditional Chinese medicine composition for treating varicose vein of lower limbs and preparation method for traditional Chinese medicine composition | |
CN101569711A (en) | Medicament for treating acne rosacea and preparation method thereof | |
CN104189865A (en) | Traditional Chinese medicine preparation for gonitis and preparation method of traditional Chinese medicine preparation | |
CN106692814A (en) | Bone disease treatment plaster and making method thereof | |
CN106362120A (en) | Traditional Chinese medicine prescription for treating hyperglycemia and diabetes | |
CN110237171A (en) | A kind of pharmaceutical composition for caput femoris necrosis and preparation method thereof and purposes | |
CN104027597A (en) | Traditional Chinese medicine for treating qi-deficiency and blood-stasis syndrome type thromboangiitis obliterans | |
CN105125860A (en) | Preparation for effectively treating osteoporosis | |
CN105998592A (en) | Traditional Chinese medicament for treating cervical spondylosis | |
CN105688074A (en) | Decoction medicine for treating hypogastric pain and preparation method of decoction medicine | |
CN105944036A (en) | Traditional Chinese medicine composition for adjuvant therapy for depression | |
CN105641425A (en) | Traditional Chinese medicine composition for treating night sweat due to yin deficiency and preparation method thereof | |
CN116440230A (en) | Traditional Chinese medicine composition for treating aplastic anemia | |
CN104873854A (en) | Traditional Chinese medicine preparation for rteriolar nephrosclerosis and preparation method thereof | |
CN104840772A (en) | External patch for relieving leg systremma and preparation method | |
CN115779025A (en) | Traditional Chinese medicine preparation for treating female acne and preparation method thereof | |
CN102886023B (en) | Prescription for treating rheumatism bone pain |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |