CN110201139A - A kind of Chinese medicinal plant oil - Google Patents
A kind of Chinese medicinal plant oil Download PDFInfo
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- CN110201139A CN110201139A CN201910628259.3A CN201910628259A CN110201139A CN 110201139 A CN110201139 A CN 110201139A CN 201910628259 A CN201910628259 A CN 201910628259A CN 110201139 A CN110201139 A CN 110201139A
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- extract
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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Abstract
The invention discloses a kind of Chinese medicinal plant oil, this vegetable oil includes Chinese medical extract, rosemary oil, radix aucklandiae seed oil, P. delavayi oil, OLEUM CYMBOPOGONIS, basil, Chinese medical extract includes ginseng extract, safflower extract, Radix Saposhnikoviae extract, Radix Gentianae Macrophyllae extract, notopterygium root extract, Folium Artemisiae Argyi extract, achyranthes bidentata extract, rhizome of chuanxiong extract, the Chinese medical extracts such as red paeonia extract, vegetable oil of the present invention is while guaranteeing to alleviate lumbar vertebra disease illness, without specific peculiar smell, and due to good penetrating power, improvement is fabulous.
Description
Technical field
The present invention relates to vegetable oil fields, and in particular to a kind of Chinese medicinal plant oil.
Background technique
Nowadays, as rhythm of life is accelerated, the routine work of people is more and more heavier, and lumbar vertebra disease is as a main disease
Disease increasingly annoyings working people, and the centrum of lumbar vertebrae is larger, and spinous process plate level stretches to rear, and relief width between adjacent spinous can
It is used as lumbar puncture, zygapophysial joint face is in sagittal plain.There are five lumbar vertebrae, centrum and rear of each lumbar vertebrae by front for human body
Attachment composition.Lumbar vertebra disease refers to because of backbone and backbone surrounding soft tissue acute and chronic injury or Lumbar Intervertebral Disc Degeneration, lumbar vertebrae bone
The reasons such as hyperplasia cause, and clinically show as also using pain in the loins, waist limitation of activity and pain in waist and lower extremities as the disease of cardinal symptom
There is pain in the loins with sciatica of nerve roots, pain mostly by buttocks, on rear side of multidirectional side thigh, outside after shank, outside instep
Side, heel or vola radiation, stand, Shi Douke's stool aggravates the pain with strength, picked and pain can be relieved or subtract after lying up
Gently, in addition if there is also the phenomenon of afflicted areas numbness after illness for a period of time.The clinical manifestation of lumbar vertebra disease is extremely numerous and complicated
Complexity is also varied.
The existing treatment method modes that generally use massage treatment, needle remorse etc., but these modes often occupy greatly
It measures the time, and uses plaster, the modes such as drug paste often and unsightly and have peculiar smell very, have some impact on to daily life, and
Existing plaster or drug paste penetration are insufficient, and the effect for alleviating illness is general.
In conclusion it is good and easy to use for alleviating the vegetable oil of lumbar vertebra disease illness to invent a kind of free from extraneous odour, effect
Seem especially Chinese medicine.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese medicinal plant oil, this vegetable oil free from extraneous odour and easy to use, in order to reach
To said effect, the present invention the following technical schemes are provided:
A kind of Chinese medicinal plant oil, including Chinese medical extract, rosemary oil, radix aucklandiae seed oil, P. delavayi oil, OLEUM CYMBOPOGONIS, sieve
Oil is strangled, the Chinese medical extract includes following substance, ginseng extract, safflower extract, Radix Saposhnikoviae extract, Radix Gentianae Macrophyllae extract,
Notopterygium root extract, Folium Artemisiae Argyi extract, achyranthes bidentata extract, rhizome of chuanxiong extract, red paeonia extract, radix dipsaci extract, atractylodes chinensis,
Rhizoma Atractylodis Macrocephalae extract, fennel fruit extract, Rhizoma Gastrodiae extract, Radix Rehmanniae extract, Rhizoma Curcumae extract, milkwort extract, extractive of pubescent angelica root coumarin,
Ginger work extract, angelica extract, eucommia ulmoides extracts, Radix Codonopsis extract, Cortex Ampelopsis Aconitifoliae Radicis extract, Rhizoma Drynariae extract, smilax
Extract, Rhizoma Atractylodis Macrocephalae extract, mountain branch seed extract, the tricky bamboo extract of the Liao Dynasty, Millettia extract.
Preferably, Chinese medical extract score by weight includes following substance, and 3 parts of ginseng extract, safflower extract 8
Part, 2 parts of Radix Saposhnikoviae extract, 9 parts of Radix Gentianae Macrophyllae extract, 8 parts of notopterygium root extract, 9 parts of Folium Artemisiae Argyi extract, 18 parts of achyranthes bidentata extract, river
8 parts of vault extract, 9 parts of red paeonia extract, 12 parts of radix dipsaci extract, 9 parts of atractylodes chinensis, 7 parts of Rhizoma Atractylodis Macrocephalae extract, fennel fruit is extracted
9 parts of object, 17 parts of Rhizoma Gastrodiae extract, 12 parts of Radix Rehmanniae extract, 8 parts of Rhizoma Curcumae extract, 9 parts of milkwort extract, extractive of pubescent angelica root coumarin 1
Part, ginger 9 parts of extract living, 12 parts of angelica extract, 3 parts of eucommia ulmoides extracts, 12 parts of Radix Codonopsis extract, Cortex Ampelopsis Aconitifoliae Radicis extract 17
Part, 9 parts of Rhizoma Drynariae extract, 7 parts of Rhizoma Smilacis Glabrae extract, 8 parts of Rhizoma Atractylodis Macrocephalae extract, 6 parts of mountain branch seed extract, the tricky bamboo extract of the Liao Dynasty
11 parts, 18 parts of Millettia extract.
Preferably, Chinese medical extract score by weight further includes 16 parts of Olibanum extract, 17 parts of Rhizoma Zingiberis extract, wood
8 parts of fragrant extract.
Preferably, the Chinese medical extract precentagewise accounts for the 10% of Chinese medicinal plant oil.
Ginseng extract: ginseng extract is formed from Hydrolysis kinetics in the root, cauline leaf of Araliaceae ginseng, is rich in
18 kinds of Saponins, are dissolved in 80 DEG C of water, are easily soluble in ethyl alcohol.It is primarily adapted for use in coronary heart diseases and angina pectoris, heart rate mistake
Slow, too fast, ventricular premature contraction, blood pressure imbalance, neurasthenia, climacteric syndrome, excessive fatigue, after being ill, postpartum, postoperative body it is empty
The symptoms such as weak;Long term usage can promote longevity, and can enhance physical strength, and treating cancer patient is because of immune function caused by radiation and chemotherapy
It is low to wait diseases;There is cold-and-heat resistent stress.The effects of there is the vigor of enhancing human body surface cell simultaneously, inhibit aging.
Safflower extract: safflower contains carthamin, carthamin yellow.Blood circulation, removing blood stasis and acesodyne, effect are menostasis, dysmenorrhea,
Lochia levies lump in the abdomen lump in the abdomen injury from falling down, sore swell and ache curative.
Radix Saposhnikoviae extract: Radix Saposhnikoviae extract is the extract of the root of umbelliferae Saposhnikovia divaricata, and effect is inducing diaphoresis to dispel wind, victory
It is wet, relieving convulsion.For cold headache, rheumatic arthralgia, spasm of limbs, rheumatism itch, tetanus.
Radix Gentianae Macrophyllae extract: gentianae macrophyllae alias, gentiana macrophylla, great Ye gentianae macrophyllae, RADIX GENTIANAE MACROPHYLLAE.Effect is wind-damp dispelling, clearing away damp-heat, only numbness
Bitterly.For muscle arteries and veins contraction, skeletal pain, afternoon tidal fever, infantile malnutrition generates heat.
Notopterygium root extract: Rhizoma Et Radix Notopterygii alias Qiang is green, shield Qiang envoy, Hu king envoy, Qiang is sliding, moves back wind envoy, black powder, Umbelliferae,
Rhizoma Et Radix Notopterygii platymiscium, effect are anemofrigid cold, and wind-cold-dampness arthralgia, item strengthening tendons are anxious, joint ache, geomantic omen edema, skin sore.
Folium Artemisiae Argyi extract: Folium Artemisiae Argyi extract is brown powder product, and using dry folium artemisiae argyi medicinal material as raw material, effect is temperature
Through stopping blooding, eliminating cold to stop pain;External application removing dampness to stop itchin.
Achyranthes bidentata extract: achyranthes bidentata extract is radix achyranthis bidentatae root extract, and effect is dispelling stasis of blood and stimulating the menstrual flow, easing joint movement, inducing diuresis for treating strangurtia.
It is used for the mass amenorrhea due to blood stasis dredging, placenta retension, arthralgia, sufficient impotence muscle contraction, cards such as hematuria blood drenches, injury from falling down.
Rhizome of chuanxiong extract: rhizome of chuanxiong extract is rhizome of chuanxiong rhizome extract, and effect is blood-activating and qi-promoting, wind-expelling pain-stopping.Effect is
Pacify nerve, positive cold and headache, abdominal mass abdominal pain, pricking pain in the chest, tumbling and swelling, headache, rheumatic arthralgia.
Red paeonia extract: for the extract of the dry root of ranunculaceae plant radix paeoniae rubra or river radix paeoniae rubra, effect is clearing heat and cooling blood, is dissipated
Stasis of blood analgesic.
Radix dipsaci extract: radix dipsaci also known as teasel root, also name river denier, radix dipsaci extract effect are nourishing liver and kidney, and continuous muscles and bones adjust blood
Arteries and veins.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia and metrostaxis, leukorrhagia, spermatorrhea, traumatic injury, metal-inflicted wound, anal fistula, ulcer sore swells.
Atractylodes chinensis: for the root extract of compositae plant Atractylis lancea, effect is drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight.
Rhizoma Atractylodis Macrocephalae extract: Rhizoma Atractylodis Macrocephalae be it is a kind of commonly use important large Chinese medicine, tool good efficacy to suffering from a deficiency of the kidney, eliminate dampness and have diuretic effect, hidroschesis peace
The functions such as tire.Rhizoma Atractylodis Macrocephalae rhizome contains volatile oil, and main component is atractylone, atractylol, atractylodes lactone etc. in oil, to treatment cirrhosis
Ascites, primary carcinoma of liver, Meniere's syndrome, chronic back pain, chordapsus and leukopenia etc. have certain curative effect.It is white
Art is widely used, other than medical treatment is formulated medication, and is the important source material of more than 40 kinds of Chinese patent medicine preparations.
Fennel fruit extract: for the fruit extract of umbelliferae fennel, for cold hernia stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea is few
Abdomen crymodynia, abdominal distention, deficiency of food are vomited and diarrhoea.Salt fennel seeds are used for cold hernia stomachache, the testis swelling and hanging down of either of the testes, through abdominal pain of trembling with fear.
Rhizoma Gastrodiae extract: orchid Rhizoma Gastrodiae stem extraction, chemical component contain gastrodin (Gastrodin, gastrodin), day
Numb glucoside member, Rhizoma Gastrodiae ether glucoside (gastrodioside), Pai Lixin (parishin), vanillyl alcohol, 2 sterol of β, parahydroxyben-zaldehyde, lemon
Lemon acid, succinic acid etc., for treat have a dizzy spell, the diseases such as extremity numbness, child convulsion, be rare Chinese medicine, closed with Qiongzhen Ganoderma Lucidum
With treatment headache and insomnia
Radix Rehmanniae extract: scrophulariaceae rehmannia glutinosa plant root extract, containing Catalpol (catalpol), a variety of amino acid and sugar, sweet
Reveal alcohol, cupreol and campesterol (campesterol) etc., is used for hot wind impairment of yin, the deep red polydipsia of tongue, spot dermexanthesis, haematemesis, nosebleed
Blood, abscess of throat.Radix rehmanniae recen clearing heat and cooling blood, yin-nourishing are promoted the production of body fluid;For pyreticosis and polydipsia, spot dermexanthesis, yin asthenia generating intrinsic heat, haematemesis, nosebleed
Blood, diabetes, catarrhal jaundice.
Rhizoma Curcumae extract: not Cheng Shu medicine, cowherb Shu, green ginger, evil mind ginger, turmeric, cure mainly " qi and blood stagnation, trusted subordinate's distending pain, disease
Lump in the abdomen, accumulation, place food do not disappear, and women's blood stasis, traumatic injury is had a pain." root tuber claims " green silk Radix Curcumae ", there is a promoting qi circulation and removing obstruction in the collateral, broken stasis of blood,
The function of analgesic.
Milkwort extract, for insomnia and dreamful sleep caused by breakdown of the normal physiological coordination between the heart and the kidney, amnesia and pavor, despicable, expectoration is not well, sore
The symptoms such as pyogenic infections, breast swell and pain.
Extractive of pubescent angelica root coumarin: can be with dispelling wind and eliminating dampness, numbness relieving and pain relieving.It is used for treating arthralgia due to cold and dampness, lumbocrural pain, few the moon volt wind headache.
Ginger work extract: for the extract of ginger.
Angelica extract: angelica extract is a kind of for replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels, and blood deficiency chlorosis is dizzy
Dizzy palpitaition, the plant of irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, dry constipation of intestines, rheumatic arthralgia, injury from falling down, ulcer sores mention
Take object.
Eucommia ulmoides extracts: containing higher chlorogenic acid, it is usually used in nourishing liver and kidney, strengthening the bones and muscles, miscarriage prevention.For lumbago due to the kidney deficiency, muscle
Bone is powerless, blood leaking in gestation, threatened abortion;Hypertension.
Radix Codonopsis extract: there is tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.For spleen and lung weakness, shortness of breath and palpitation, anorexia and loose stool, asthma void
The effect of cough, Heat Diabetes.
Cortex Ampelopsis Aconitifoliae Radicis extract: also known as sheep vine shoot, careless grape, madder, blood, contaminate red, cyperus alternifolius, have promoting blood circulation to remove blood stasis, disappear
The effect of inflammation analgesic.
Rhizoma Drynariae extract: the rhizome of davallia is Davalliaceae, and Davallia is grown nonparasitically upon another plant pteridophyte, is rich in flavones, alkaloid, phenol
The effective components such as class have removing blood stasis and acesodyne, reunion of bone, toothache, Low Back Pain, chronic diarrhea and other effects
Rhizoma Smilacis Glabrae extract: for liliaceous plant smilacis glabra rhizome extract, there is removing toxic substances, dehumidifying is easing joint movement.
Rhizoma Atractylodis Macrocephalae extract: there is air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distention diarrhea, phlegm retention
The effect of feel dizzy and heart palpitations, oedema, spontaneous perspiration, threatened abortion.
Mountain branch seed extract: there is heat-clearing, purging intense heat, cool blood.Pyreticosis restlessness of asrhenia type and insomnia, jaundice are controlled, stranguria syndrome is quenched one's thirst, hot eyes, pharynx
Bitterly, haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer sprain the effect of swelling and ache.
The tricky bamboo extract of the Liao Dynasty: the not celestial track of distant Diao Zhu alias, RADIX CYNANCHI PANICULATI, carefree bamboo, distant bamboo be free and unfettered, precious jade mangosteen, Diao Zhu, to section
Lotus, leaf of bamboo asarum, bronze gong grass, cynanchum paniculatum, lemonfragrant ostericum root, have effects that analgesia, cough-relieving, inducing diuresis for removing edema, promoting blood circulation and detoxication
Millettia extract: Millettia extract, general flavone and its contained chemical component have a variety of pharmacological activity, including
Influence to blood circulation system, antitumor, antiviral, anti-oxidant etc..
Olibanum extract: it for the powdered mobility extract of yellow-white of the resin of olive subject plant Cattell Boswellia carterii, uses
In controlling qi and blood stagnation, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, dysmenorrhea, postpartum blood stasis stabbing pain.
Rhizoma Zingiberis extract: it is used for coldness and pain in the epigastrium, vomiting and diarrhea, cold weak pulse of limb, cold drink to breath with cough.
Radix Aucklandiae extract: have the effect of protecting enteron aisle and antibacterial.
Beneficial effect
The present invention in vegetable oil by adding ginseng extract, safflower extract, Radix Saposhnikoviae extract, Radix Gentianae Macrophyllae extract,
Notopterygium root extract, Folium Artemisiae Argyi extract, achyranthes bidentata extract, rhizome of chuanxiong extract, the Chinese medical extracts such as red paeonia extract are guaranteeing to alleviate
While lumbar vertebra disease illness, no specific peculiar smell, and due to good penetrating power, improvement is fabulous.
Specific embodiment
The present invention is further elaborated with the following Examples.
Embodiment 1
Chinese medicinal plant oil includes rosemary oil 25g, radix aucklandiae seed oil 5g, P. delavayi oil 8g, OLEUM CYMBOPOGONIS 17g, basil
35g, Chinese medical extract 10g, wherein Chinese medical extract score by weight is by following material composition, and 3 parts of ginseng extract, safflower mentions
Take 8 parts of object, 2 parts of Radix Saposhnikoviae extract, 9 parts of Radix Gentianae Macrophyllae extract, 8 parts of notopterygium root extract, 9 parts of Folium Artemisiae Argyi extract, achyranthes bidentata extract 18
Part, it is 8 parts of rhizome of chuanxiong extract, 9 parts of red paeonia extract, 12 parts of radix dipsaci extract, 9 parts of atractylodes chinensis, 7 parts of Rhizoma Atractylodis Macrocephalae extract, small
9 parts of fennel extract, 17 parts of Rhizoma Gastrodiae extract, 12 parts of Radix Rehmanniae extract, 8 parts of Rhizoma Curcumae extract, 9 parts of milkwort extract, Radix Angelicae Pubescentis mentions
1 part of object is taken, ginger 9 parts of extract living, 12 parts of angelica extract, 3 parts of eucommia ulmoides extracts, 12 parts of Radix Codonopsis extract, Cortex Ampelopsis Aconitifoliae Radicis extracts
17 parts of object, 9 parts of Rhizoma Drynariae extract, 7 parts of Rhizoma Smilacis Glabrae extract, 8 parts of Rhizoma Atractylodis Macrocephalae extract, 6 parts of mountain branch seed extract, distant Diao Zhuti
Take 11 parts of object, 18 parts of Millettia extract.
Wherein said extracted object prepares extract using alcohol extracting method, by rosemary oil, radix aucklandiae seed oil, P. delavayi oil, rue
Vanilla flavour concentrate, basil and Chinese medical extract, which are mixed evenly, obtains Chinese medicinal plant oil.
Embodiment 2
Chinese medicinal plant oil includes rosemary oil 25g, radix aucklandiae seed oil 5g, P. delavayi oil 8g, OLEUM CYMBOPOGONIS 17g, basil
35g, Chinese medical extract 10g, wherein Chinese medical extract score by weight is by following material composition, and 3 parts of ginseng extract, safflower mentions
Take 8 parts of object, 2 parts of Radix Saposhnikoviae extract, 9 parts of Radix Gentianae Macrophyllae extract, 8 parts of notopterygium root extract, 9 parts of Folium Artemisiae Argyi extract, achyranthes bidentata extract 18
Part, it is 8 parts of rhizome of chuanxiong extract, 9 parts of red paeonia extract, 12 parts of radix dipsaci extract, 9 parts of atractylodes chinensis, 7 parts of Rhizoma Atractylodis Macrocephalae extract, small
9 parts of fennel extract, 17 parts of Rhizoma Gastrodiae extract, 12 parts of Radix Rehmanniae extract, 8 parts of Rhizoma Curcumae extract, 9 parts of milkwort extract, Radix Angelicae Pubescentis mentions
1 part of object is taken, ginger 9 parts of extract living, 12 parts of angelica extract, 3 parts of eucommia ulmoides extracts, 12 parts of Radix Codonopsis extract, Cortex Ampelopsis Aconitifoliae Radicis extracts
17 parts of object, 9 parts of Rhizoma Drynariae extract, 7 parts of Rhizoma Smilacis Glabrae extract, 8 parts of Rhizoma Atractylodis Macrocephalae extract, 6 parts of mountain branch seed extract, distant Diao Zhuti
Take 11 parts of object, 18 parts of Millettia extract, 16 parts of Olibanum extract, 17 parts of Rhizoma Zingiberis extract, 8 parts of Radix Aucklandiae extract.
Wherein said extracted object prepares extract using alcohol extracting method, by rosemary oil, radix aucklandiae seed oil, P. delavayi oil, rue
Vanilla flavour concentrate, basil and Chinese medical extract, which are mixed evenly, obtains Chinese medicinal plant oil.
Comparative example 1, the difference with embodiment 1, which is only that, is not added with safflower extract, other preparation methods and condition with
Embodiment 1 is identical.
Comparative example 2, the difference with embodiment 1, which is only that, is not added with Cortex Ampelopsis Aconitifoliae Radicis extract, other preparation methods and condition
It is same as Example 1.
Comparative example 3, the difference with embodiment 1, which is only that, is not added with milkwort extract, other preparation methods and condition with
Embodiment 1 is identical.
Comparative example 4, the difference with embodiment 1, which is only that, is not added with fennel fruit extract, other preparation methods and condition with
Embodiment 1 is identical.
Comparative example 5, the difference with embodiment 1, which is only that, was not added with atractylodes chinensis, other preparation methods and condition
It is same as Example 1.
Comparative example 6, the difference with embodiment 1, which is only that, is not added with red paeonia extract, other preparation methods and condition with
Embodiment 1 is identical.
Comparative example 7, the difference with embodiment 1, which is only that, is not added with Radix Rehmanniae extract, other preparation methods and condition with
Embodiment 1 is identical.
Comparative example 8, the difference with embodiment 2, which is only that, is not added with Olibanum extract, other preparation methods and condition with
Embodiment 1 is identical.
Comparative example 9, the difference with embodiment 2, which is only that, is not added with Radix Aucklandiae extract, other preparation methods and condition with
Embodiment 1 is identical.
Skin sensibiligen research:
Test method: without cavy 20 is hurt, [2 grades of Hartley cavys, are tested health by Nat'l Pharmaceutical & Biological Products Control Institute
Animal breeding field provides, and half male and half female, weight 180-220g is randomly divided into two groups, i.e. intact skin group and damaged skin group.By
Examination guinea pig back two sides unhairing about 34cm (about body surface area 10%) for 24 hours, and will wherein 10 production damaged skins.It is losing hair or feathers
And breakage smears the vegetable oil of 5cm × 6cm embodiment of the present invention 1, and 7d is observed continuously.
As a result observe: it is observed that two groups of cavys do not reveal any abnormalities reaction, weight, skin, hair color, eye mucosa,
Stool, breathing, four limbs activity, behavior etc. do not reveal any abnormalities phenomenon.Therefore it is believed that the vegetable oil in cavy external application
When without any acute toxic reaction occur.
2) skin irritation test:
Test method: health is without hurting cavy 5, weight 150~200g, it is tested before for 24 hours, guinea pig back unhairing 40cm2 is (about
For body surface area 12%).Divide intact skin administration area, damaged skin that area, intact skin check plot, damaged skin check plot is administered
Deng 4 areas, every area is body surface area 3%.Retain suitable distance between each area.The plant that the embodiment of the present invention 1 is smeared in area is administered
Object oil, observes skin conditions.It is observed continuously 1 week.
As a result observe: when each coating and last removal remains tested material 1,24,48,72h, administration skin and blank pair
Compare according to area's skin, either damaged skin area or intact skin Qu Junwu significant difference, was both formed without erythema, also without oedema
Occur, it is 0 that stimulus intensity, which can be evaluated, therefore is believed that the vegetable oil cavy external application occurs without any irritative response.
3) skin allergy test:
Test method: albino guinea-pig 30, half male and half female, weight 250~300g, it is tested before for 24 hours, guinea pig back two sides are gone
Hair, every side about 3cm × 3cm.Cavy is randomly divided into 3 groups, every group 10 (half male and half female) by weight, gender.1st group to implementation
The vegetable oil of example 1, the 2nd group of blank control, the 3rd group of positive control is (to positive sensitizer, i.e. 1%2,4- dinitro-chloro-benzene
0.2ml)。
Sensitization contact: being applied to hair removal section on the left of animal for vegetable oil, and every animal sub-cage rearing continues 6h, throws off, the
It 7 days and the 14th day, is in kind respectively repeated 1 times, amounts to 3 times.Positive test is done simultaneously.
Excitation contact: in last to the 14th day after tested material sensitization, vegetable oil is applied to hair removal section on the right side of guinea pig back
(losing hair or feathers for 24 hours before examination), positive control is observed, so at once with tested material is removed after 0.1%2,4- dinitro-chloro-benzene 0.2ml, 6h
Cutaneous anaphylaxis situation is observed again in 24,48,72h afterwards.
As a result observe: positive controls have most animals obvious allergic reaction occur in different time, and have minority to go out
Existing Mild edema, and then skin gloss is lubricious as usual for vegetable oil and blank control (matrix) administration area, it is smooth wrinkle-free, both without erythema
It is formed, is also occurred without oedema, vegetable oil of the present invention does not find any allergic reaction through allergic reaction on guinea pigs.
Arthralgic treatment verifying:
Choose natural joint pain population (being randomly selected in volunteer) 220, be equally divided into 12 groups, embodiment 1-2 and
Comparative example 1-9, every group of 20 people count each group curative effect;It is checked after 40 days or phone tracks follow-up, whether there is or not arthralgia occur for investigation
Recurrence.
Curative effect judging standard: cure: painful swelling of joints disappears, and activity is normal;Effective: painful swelling of joints is substantially reduced, and activity is just
Often;Effective: above-mentioned symptom mitigates, and joint motion improves;Invalid: symptom and sign without improvement or deteriorates compared with before treatment.
As a result it see the table below 1:
Table 1
It cures (number) | Effective (number) | Effectively (number) | (number) in vain | |
Embodiment 1 | 4 | 13 | 4 | 0 |
Embodiment 2 | 10 | 8 | 2 | 0 |
Comparative example 1 | 0 | 1 | 10 | 9 |
Comparative example 2 | 0 | 0 | 9 | 11 |
Comparative example 3 | 0 | 0 | 12 | 8 |
Comparative example 4 | 0 | 0 | 11 | 9 |
Comparative example 5 | 1 | 1 | 11 | 7 |
Comparative example 6 | 1 | 1 | 10 | 8 |
Comparative example 7 | 1 | 0 | 4 | 15 |
Comparative example 8 | 4 | 15 | 1 | 0 |
Comparative example 9 | 5 | 15 | 0 | 0 |
Table 1 cooperates with increasing synergy as it can be seen that comparing various active constituents in the visible present invention with embodiment 1 by comparative example 1-7, reaches
To arthralgic effect is alleviated, visible addition is compared by embodiment 2 and embodiment 1, it can by comparative example 8-9 and the comparison of embodiment 2
See that addition Olibanum extract, Rhizoma Zingiberis extract, to alleviate arthralgic effect after Radix Aucklandiae extract more significant, by comparative example 8-9
It compares with embodiment 2 as it can be seen that Olibanum extract, Rhizoma Zingiberis extract, Radix Aucklandiae extract cooperate with so that alleviating arthralgic effect more
It is significant.Only 4 people indicate that vegetable oil has uncomfortable peculiar smell in test.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (4)
1. a kind of Chinese medicinal plant oil, including Chinese medical extract, rosemary oil, radix aucklandiae seed oil, P. delavayi oil, OLEUM CYMBOPOGONIS, sweet basil
Oil, which is characterized in that the Chinese medical extract includes following substance, ginseng extract, safflower extract, Radix Saposhnikoviae extract, the Qin
Macrophylla extract, notopterygium root extract, Folium Artemisiae Argyi extract, achyranthes bidentata extract, rhizome of chuanxiong extract, red paeonia extract, radix dipsaci extract are grey
Art extract, Rhizoma Atractylodis Macrocephalae extract, fennel fruit extract, Rhizoma Gastrodiae extract, Radix Rehmanniae extract, Rhizoma Curcumae extract, milkwort extract, solely
Extract living, ginger extract living, angelica extract, eucommia ulmoides extracts, Radix Codonopsis extract, Cortex Ampelopsis Aconitifoliae Radicis extract, the rhizome of davallia extract
Object, Rhizoma Smilacis Glabrae extract, Rhizoma Atractylodis Macrocephalae extract, mountain branch seed extract, the tricky bamboo extract of the Liao Dynasty, Millettia extract.
2. Chinese medicinal plant oil as described in claim 1, which is characterized in that Chinese medical extract score by weight includes following
Substance, 3 parts of ginseng extract, 8 parts of safflower extract, 2 parts of Radix Saposhnikoviae extract, 9 parts of Radix Gentianae Macrophyllae extract, 8 parts of notopterygium root extract, Chinese mugwort
9 parts of leaf extract, 18 parts of achyranthes bidentata extract, 8 parts of rhizome of chuanxiong extract, 9 parts of red paeonia extract, 12 parts of radix dipsaci extract, rhizoma atractylodis mention
Take 9 parts of object, 7 parts of Rhizoma Atractylodis Macrocephalae extract, 9 parts of fennel fruit extract, 17 parts of Rhizoma Gastrodiae extract, 12 parts of Radix Rehmanniae extract, Rhizoma Curcumae extract 8
Part, 9 parts of milkwort extract, 1 part of extractive of pubescent angelica root coumarin, ginger 9 parts of extract living, 12 parts of angelica extract, 3 parts of eucommia ulmoides extracts, party
12 parts of conopsea extraction, 17 parts of Cortex Ampelopsis Aconitifoliae Radicis extract, 9 parts of Rhizoma Drynariae extract, 7 parts of Rhizoma Smilacis Glabrae extract, 8 parts of Rhizoma Atractylodis Macrocephalae extract,
6 parts of mountain branch seed extract, tricky 11 parts of bamboo extract, 18 parts of Millettia extract of the Liao Dynasty.
3. Chinese medicinal plant oil as described in claim 1, which is characterized in that Chinese medical extract score by weight further includes cream
16 parts of fragrant extract, 17 parts of Rhizoma Zingiberis extract, 8 parts of Radix Aucklandiae extract.
4. Chinese medicinal plant oil as described in claim 1, which is characterized in that the Chinese medical extract precentagewise accounts for Chinese medicinal plant
The 10% of oil.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1839941A (en) * | 2006-01-24 | 2006-10-04 | 赵福勤 | Chinese prepared medicine for treating bone pain |
CN107158349A (en) * | 2017-06-13 | 2017-09-15 | 广州赛美化妆品有限公司 | A kind of draft leads to nutrient solution and preparation method thereof |
CN107441461A (en) * | 2016-06-01 | 2017-12-08 | 陈丽 | A kind of Chinese medicine for controlling the protrasion of the lumbar intervertebral disci |
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2019
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1839941A (en) * | 2006-01-24 | 2006-10-04 | 赵福勤 | Chinese prepared medicine for treating bone pain |
CN107441461A (en) * | 2016-06-01 | 2017-12-08 | 陈丽 | A kind of Chinese medicine for controlling the protrasion of the lumbar intervertebral disci |
CN107158349A (en) * | 2017-06-13 | 2017-09-15 | 广州赛美化妆品有限公司 | A kind of draft leads to nutrient solution and preparation method thereof |
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