CN110201053B - Miao medicine prostate paste and preparation method thereof - Google Patents

Miao medicine prostate paste and preparation method thereof Download PDF

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CN110201053B
CN110201053B CN201910635617.3A CN201910635617A CN110201053B CN 110201053 B CN110201053 B CN 110201053B CN 201910635617 A CN201910635617 A CN 201910635617A CN 110201053 B CN110201053 B CN 110201053B
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paste
prostate
miao medicine
amber
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CN110201053A (en
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王俊伟
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Henan Baima Health Industry Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/10Peat; Amber; Turf; Humus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus

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Abstract

The invention relates to a Miao medicine prostate paste, which is prepared from the following raw materials in parts by weight: 300 parts of Touhihouxiang, 200 parts of Jiuzu tea, 80-150 parts of pyrrosia lingua, 70-140 parts of Japanese climbing fern spore, 80-150 parts of semen plantaginis, 90-160 parts of salted phellodendron, 70-140 parts of astragalus, 80-150 parts of epimedium, 90-160 parts of achyranthes and 30-80 parts of amber. The Miao medicine prostate paste is prepared by the steps of crushing medicinal materials, preparing paste, coating, slicing, packaging and the like. The invention relates to a patch developed according to the Miao medicine theory, which takes Guizhou Miao medicine Touguxiang and sarcandra glabra as main medicines and is used by being combined with other auxiliary medicines, and has the effects of promoting recovery and health care on frequent micturition, urgent micturition, urethral pain and the like caused by prostatic hyperplasia and prostatitis; the selected medicinal materials are local common traditional Chinese medicines, and the medicinal materials are convenient to select, low in cost and good in curative effect.

Description

Miao medicine prostate paste and preparation method thereof
Technical Field
The invention relates to a Miao medicine prostate paste and a preparation method thereof.
Background
Prostate diseases are not single diseases, but a group of clinical syndromes, which are manifested by abnormal urination symptoms such as frequent urination, urgent urination, painful urination, difficult urination, incomplete urination, and the like, and discomfort or pain at parts such as perineum, lower abdomen, penis, scrotum, lumbosacral part, and the like, and are comprehensive symptoms with various unique forms. In the outpatient service of urology andrology in China, the prostate disease accounts for 25-30% of patients in clinic, most of the patients are adult men under 50 years old, and the patients who have had prostate symptoms in the lifetime of men account for 50% and the recurrence rate is as high as 20-50%. The causes of prostate diseases are complex, the pathogenesis is not completely understood, and the diagnosis standard and the treatment method are not uniform. Prostate diseases are easy to combine with male infertility and sexual dysfunction, and seriously affect the quality of life of patients. The medicines selected by western medicine usually affect liver and kidney, have great side effects and long treatment period, and have unsatisfactory effect, so the medicines are often unacceptable for patients. Therefore, patients are expected to have safer, effective and stable health care treatment approaches.
Disclosure of Invention
In order to solve the technical problem, the technical scheme adopted by the invention is as follows:
a Miao medicine prostate paste, which is characterized in that: the composition is prepared from the following raw materials in parts by weight: 300 parts of Touhihouxiang, 200 parts of Jiuzu tea, 80-150 parts of pyrrosia lingua, 70-140 parts of Japanese climbing fern spore, 80-150 parts of semen plantaginis, 90-160 parts of salted phellodendron, 70-140 parts of astragalus, 80-150 parts of epimedium, 90-160 parts of achyranthes and 30-80 parts of amber.
Preferably, the Miao medicine prostate paste consists of the following raw materials in parts by weight: 250 parts of Tou Gu Xiang 170, 170 parts of Jiu Jie tea 130, 90-130 parts of pyrrosia lingua, 80-120 parts of Japanese climbing fern spore, 80-130 parts of semen plantaginis, 90-140 parts of salted phellodendron, 80-130 parts of astragalus, 90-130 parts of epimedium, 90-140 parts of achyranthes root and 30-60 parts of amber.
Preferably, the Miao medicine prostate paste consists of the following raw materials in parts by weight: 220 parts of Touhua Persicolor herb 180, 160 parts of sarcandra glabra 140, 90-110 parts of pyrrosia lingua, 90-120 parts of climbing fern spore, 80-110 parts of semen plantaginis, 90-120 parts of salted cortex phellodendri, 95-115 parts of radix astragali, 95-105 parts of herba Epimedii, 90-115 parts of radix Achyranthis bidentatae and 40-55 parts of amber.
Preferably, the Miao medicine prostate paste consists of the following raw materials in parts by weight: 200 parts of Tou Gu Xiang, 150 parts of sarcandra glabra, 100 parts of pyrrosia lingua, 100 parts of spora lygodii, 100 parts of semen plantaginis, 100 parts of salted golden cypress, 100 parts of radix astragali, 100 parts of herba epimedii, 100 parts of radix achyranthis bidentatae and 50 parts of amber.
Preferably, the preparation method of the Miao medicine prostate paste comprises the following steps:
(1) crushing medicinal materials: weighing the lysimachia christinae hance, the sarcandra glabra, the pyrrosia lingua, the climbing fern spore, the plantain seed, the salted phellodendron bark, the astragalus root, the epimedium herb, the achyranthes root and the amber in sequence according to the formula amount, respectively sieving the components by 20 meshes to obtain coarse powder, mixing the coarse powder, sieving by 80 meshes to obtain fine powder, wherein the fine powder is the feeding medicine powder.
(2) Preparing paste: adding a certain amount of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the feeding medicinal powder, stirring for 1 hour until the medicinal powder and the hot-melt pressure-sensitive adhesive liquid are fully mixed to obtain a mixture, and keeping the temperature of the obtained mixture to 60 ℃ to obtain the adhesive plaster.
(3) Coating: and starting the coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, and keeping coating after the amount of the coated glue paste is adjusted to meet the standard requirement according to the requirement.
(4) Slicing: the coated coil was left to stand for 24 hours, and the coated coil was sliced with a slitter to obtain a paste patch.
(5) Subpackaging: and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Preferably, the patch has a size of 9cm × 13cm, and each patch is coated with a paste in an amount of 3 g.
Preferably, the amount of the hot melt pressure sensitive adhesive is 4900 parts.
The bone-penetrating incense is pungent in taste and warm in nature, and can expel wind and remove dampness, relax muscles and stimulate blood circulation, remove blood stasis and detumescence, detoxify and relieve eye pain; herba Pileae Scriptae, bitter and pungent in taste, neutral in nature, has effects of clearing heat, cooling blood, promoting blood circulation, removing speckle, dispelling pathogenic wind, and dredging collaterals; pyrrosia lingua is sweet and bitter in taste and slightly cold in nature, and has the effects of inducing diuresis for treating stranguria, clearing away lung-heat, relieving cough, cooling blood and stopping bleeding; spora Lygodii is sweet, salty and cold in taste, and has effects of clearing away damp-heat, treating stranguria and relieving pain; semen plantaginis has sweet taste and cold nature, and has effects of clearing heat, promoting urination, treating stranguria, eliminating dampness, relieving diarrhea, improving eyesight, and eliminating phlegm; radix astragali, sweet in taste, slightly warm in nature, has effects of invigorating qi, invigorating yang, consolidating superficial resistance, arresting sweating, inducing diuresis, relieving swelling, promoting fluid production, and nourishing blood; the golden cypress is bitter in taste and cold in nature, and has the effects of clearing heat, drying dampness, purging fire, removing steam, detoxifying and treating sore; herba Epimedii is warm in nature, pungent and sweet in flavor, and has effects of invigorating kidney yang, strengthening tendons and bones, and dispelling pathogenic wind and dampness; achyranthes bidentata, slightly bitter in taste and cool in nature, has the functions of clearing heat, detoxifying and promoting urination; amber, sweet in flavor, neutral in nature, has effects of tranquilizing, promoting urination, and promoting blood circulation; borneol is colorless transparent or white semitransparent flaky crisp crystal, is pungent and bitter in taste and slightly cold in nature, and can induce resuscitation, refresh mind, clear heat and relieve pain.
Compared with the prior art, the invention has the following advantages: the invention relates to a patch which is developed according to the Miao medicine theory, Guizhou Miao medicine Touguxiang and sarcandra glabra are taken as monarch drugs, pyrrosia lingua and climbing fern spore are taken as ministerial drugs, semen plantaginis, radix astragali, golden cypress, herba epimedii, radix achyranthis bidentatae and amber are taken as assistant and guide drugs, and ten drugs are compatible and used together, so that the patch has the auxiliary effect of promoting recovery on frequent micturition, urgent micturition, urethral pain and the like caused by prostatic hyperplasia and prostatitis; the selected medicinal materials are local common traditional Chinese medicines, and the medicinal materials are convenient to select, low in cost and good in curative effect.
Detailed Description
The following further describes embodiments of the present invention with reference to examples. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.
The specific embodiment of the invention is as follows:
a Miao medicine prostate paste is composed of the following raw materials in parts by weight: 300 parts of Touhihouxiang, 200 parts of Jiuzu tea, 80-150 parts of pyrrosia lingua, 70-140 parts of Japanese climbing fern spore, 80-150 parts of semen plantaginis, 90-160 parts of salted phellodendron, 70-140 parts of astragalus, 80-150 parts of epimedium, 90-160 parts of achyranthes and 30-80 parts of amber.
Preferably, the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 250 parts of Tou Gu Xiang 170, 170 parts of Jiu Jie tea 130, 90-130 parts of pyrrosia lingua, 80-120 parts of Japanese climbing fern spore, 80-130 parts of semen plantaginis, 90-140 parts of salted phellodendron, 80-130 parts of astragalus, 90-130 parts of epimedium, 90-140 parts of achyranthes root and 30-60 parts of amber.
Preferably, the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 220 parts of Touhua Persicolor herb 180, 160 parts of sarcandra glabra 140, 90-110 parts of pyrrosia lingua, 90-120 parts of climbing fern spore, 80-110 parts of semen plantaginis, 90-120 parts of salted cortex phellodendri, 95-115 parts of radix astragali, 95-105 parts of herba Epimedii, 90-115 parts of radix Achyranthis bidentatae and 40-55 parts of amber.
Preferably, the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 200 parts of Tou Gu Xiang, 150 parts of sarcandra glabra, 100 parts of pyrrosia lingua, 100 parts of spora lygodii, 100 parts of semen plantaginis, 100 parts of salted golden cypress, 100 parts of radix astragali, 100 parts of herba epimedii, 100 parts of radix achyranthis bidentatae and 50 parts of amber.
The preparation method of the Miao medicine prostate paste comprises the following steps: weighing the lysimachia christinae hance, the sarcandra glabra, the pyrrosia lingua, the climbing fern spore, the plantain seed, the salted phellodendron bark, the astragalus root, the epimedium herb, the achyranthes root and the amber in sequence according to the formula amount, respectively sieving the components by a sieve of 20 meshes to obtain coarse powder, mixing the coarse powder, sieving by a sieve of 80 meshes to obtain fine powder, wherein the fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the feeding medicinal powder, stirring for 1 hour until the medicinal powder and the hot-melt pressure-sensitive adhesive liquid are fully mixed to obtain a mixture, and keeping the temperature of the obtained mixture to 60 ℃ to obtain an adhesive paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine to obtain slices, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of the coated adhesive plaster is 3g, so that 1200 plaster patches can be prepared; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
The using method comprises the following steps: firstly, the hands of a patient should be kept clean, the patient should be wiped on the Shenque point by alcohol cotton to avoid the symptoms of local infection, then the patch is pasted on the Shenque point of the patient for 24 hours each time, and the next patch is pasted after the patch is removed and the interval is 2 hours.
The formula of the invention takes the lysimachia christinae hance and the sarcandra glabra nakai as monarch drugs, the pyrrosia lingua and the climbing fern spore as ministerial drugs, the plantain seed, the astragalus, the phellodendron, the epimedium, the achyranthes and the amber as assistant drugs, and the ten drugs are compatible and combined for use, thereby having the auxiliary effect of promoting the recovery of frequent micturition, urgent micturition, urethral pain and the like caused by prostatitis. The product of the invention is tested by a toxicity test center, and the test result of the microbial indexes is as follows: the total number of bacterial colonies, mould and microzyme, faecal coliform group, staphylococcus aureus and pseudomonas aeruginosa, which meet the standard of 2015 edition of cosmetic health Specification of Ministry of health; the results of sanitary chemical detection and toxicological evaluation meet the 2015 edition standard of 'cosmetic hygiene Standard' of Ministry of health; the inspection results show that the product meets the national relevant standards and is safe to use.
Example 1
Taking 150 parts of Tou Guxiang, 130 parts of sarcandra glabra, 80 parts of pyrrosia lingua, 70 parts of spora lygodii, 80 parts of semen plantaginis, 90 parts of salted cortex phellodendri, 70 parts of radix astragali, 80 parts of herba epimedii, 90 parts of radix achyranthis bidentatae and 30 parts of amber, respectively crushing the raw materials into coarse powder by 20 meshes, then uniformly mixing the coarse powder and the coarse powder, and crushing the mixture into fine powder by 80 meshes, wherein the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Example 2
300 parts of Tou Gu Xiang, 200 parts of sarcandra glabra, 150 parts of pyrrosia lingua, 140 parts of climbing fern spore, 150 parts of plantain seed, 160 parts of salted phellodendron, 140 parts of astragalus, 150 parts of epimedium, 160 parts of achyranthes and 80 parts of amber are respectively ground into coarse powder by 20 meshes, then the coarse powder is mixed uniformly and ground into fine powder by 80 meshes, and the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Example 3
Respectively crushing 170 parts of Tou Guxiang, 130 parts of sarcandra glabra, 90 parts of pyrrosia lingua, 80 parts of climbing fern spore, 80 parts of semen plantaginis, 90 parts of salted cortex phellodendri, 80 parts of radix astragali, 90 parts of herba epimedii, 90 parts of radix achyranthis bidentatae and 30 parts of amber into coarse powder by 20 meshes, then uniformly mixing, and crushing into fine powder by 80 meshes, wherein the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Example 4
250 parts of Tou Gu Xiang, 170 parts of sarcandra glabra, 130 parts of pyrrosia lingua, 120 parts of climbing fern spore, 130 parts of semen plantaginis, 140 parts of salted golden cypress, 130 parts of radix astragali, 130 parts of herba epimedii, 140 parts of radix achyranthis bidentatae and 60 parts of amber are respectively ground into coarse powder by 20 meshes, then the coarse powder is mixed uniformly and ground into fine powder by 80 meshes, and the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Example 5
180 parts of Tou Gu Xiang, 140 parts of sarcandra glabra, 90 parts of pyrrosia lingua, 90 parts of spora lygodii, 80 parts of semen plantaginis, 90 parts of salted cortex phellodendri, 95 parts of radix astragali, 95 parts of herba epimedii, 90 parts of radix achyranthis bidentatae and 40 parts of amber are respectively ground into coarse powder by 20 meshes, then the coarse powder is mixed uniformly and ground into fine powder by 80 meshes, and the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Example 6
220 parts of Tou Gu Xiang, 160 parts of sarcandra glabra, 110 parts of pyrrosia lingua, 120 parts of climbing fern spore, 110 parts of plantain seed, 120 parts of salted phellodendron, 115 parts of astragalus, 105 parts of epimedium, 115 parts of achyranthes and 55 parts of amber are respectively crushed into coarse powder by 20 meshes, then the coarse powder is uniformly mixed and crushed into fine powder by 80 meshes, and the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Example 7
Respectively crushing 200 parts of lysimachia christinae hance, 150 parts of sarcandra glabra, 100 parts of pyrrosia lingua, 100 parts of spora lygodii, 100 parts of semen plantaginis, 100 parts of salted cortex phellodendri, 100 parts of radix astragali, 100 parts of herba epimedii, 100 parts of radix achyranthis bidentatae and 50 parts of amber into coarse powder by 20 meshes, then uniformly mixing, and crushing into fine powder by 80 meshes, wherein the obtained fine powder is the medicine powder for feeding; adding 4900 parts of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted, adding the medicinal powder for feeding, stirring for 1 hour until the medicinal powder and the glue solution of the hot-melt pressure-sensitive adhesive are fully mixed to obtain a mixture, and keeping the temperature of the mixture to 60 ℃ to obtain a glue paste; starting a coating machine, preheating for 20 minutes, injecting the glue paste into the coating machine by using a pump for pre-coating, adjusting the amount of the coated glue paste according to requirements until the amount meets the standard requirements, and keeping coating; placing the coated coiled material for 24 hours, and slicing the coated coiled material by using a splitting machine, wherein the obtained slices are plaster patches, the size of each plaster patch is 9cm multiplied by 13cm, and the amount of plaster coated on each plaster patch is 3 g; and (3) filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product.
Examples of treatments
200 prostate disease patients who have been diagnosed before are selected, the prostate disease patients are 35-60 years old, symptoms are mainly manifested as abnormal urination symptoms such as frequent micturition, urgent urination, painful urination, difficult urination, incomplete urination and the like, discomfort or pain at parts such as perineum, lower abdomen, penis, scrotum, lumbosacral part and the like, and the patch of the invention is used according to the use instructions. If the patient has normal urine, smooth urination and no lower abdominal distending pain, the patient is judged to be cured; if the patient urinates by himself, but the lower abdomen still has slight distending pain, the effect is judged to be effective; a patient is judged to be ineffective if the clinical symptoms have not improved or even become more severe than before. After the patch 30 disclosed by the invention is used for sticking, 180 cases are cured, 192 cases are effective, 8 cases are ineffective, the cure rate is 90%, the effective rate is 96%, and adverse reactions and anaphylactic reactions of patients are not found in the use process.
Typical cases
Case 1: wangzhi, male, age 40, the patient complains about frequent urination, feeling of incomplete urination always, and burning pain of urethra when urinating, and the number of urination decreases after the patch 10 of the present invention is used, but the feeling of pain of urination also appears, and the symptom of pain of urination disappears after the patch 30 is used.
Case 2: when the male is in age of 48, the patient mainly complains of frequent micturition, painful urination and difficult urination, and the pain of the perineum and the lower abdomen is aggravated when the male sits on the patch 8, the urination condition is improved after the patch is used, the urination can be performed automatically, the urination frequency is reduced, and the pain symptoms of the perineum and the lower abdomen disappear after the patch is used for 30 times.
Case 3: in 52 years old male, the patient mainly complains about unsmooth urination and dribbling before 2 years, the patient is diagnosed with prostatauxe before one year, poor sleep quality at night, soreness and weakness of waist and knees, and accompanied with symptoms of urgent micturition, odynuria, frequent micturition and the like, and the effect is not good after taking Nishutong and pulean. After the patch 30 of the invention is continuously used, the frequent micturition, urgent micturition and the like are relieved, and the sleep quality is improved.
Case 4: li Shi, male 45 years old, patients complain about prostate hypertrophy and pain of lower abdomen like acupuncture when they are 40 years old, the western medicine taken by many hospitals is ineffective, and the patients stop taking the patch 30 of the invention after sticking, all are normal, and the disease is not recurred at present.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various changes and modifications can be made without departing from the overall concept of the present invention, and these should also be considered as the protection scope of the present invention.

Claims (4)

1. A Miao medicine prostate paste, which is characterized in that: the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 300 parts of Touhihouxiang, 200 parts of sarcandra glabra, 80-150 parts of pyrrosia lingua, 70-140 parts of climbing fern spore, 80-150 parts of semen plantaginis, 90-160 parts of salted phellodendron, 70-140 parts of astragalus, 80-150 parts of epimedium, 90-160 parts of achyranthes and 30-80 parts of amber;
the preparation method of the Miao medicine prostate paste comprises the following steps:
(1) crushing medicinal materials: weighing the lysimachia christinae hance, the sarcandra glabra, the pyrrosia lingua, the climbing fern spore, the plantain seed, the salted phellodendron bark, the astragalus root, the epimedium herb, the achyranthes root and the amber in sequence according to the formula amount, respectively sieving the components by a sieve of 20 meshes to obtain coarse powder, mixing the coarse powder, sieving by a sieve of 80 meshes to obtain fine powder, wherein the fine powder is the medicine powder for feeding;
(2) preparing paste: adding a certain amount of hot-melt pressure-sensitive adhesive into a stirring tank, heating until the hot-melt pressure-sensitive adhesive is completely melted to obtain a hot-melt pressure-sensitive adhesive liquid, then adding the feeding medicinal powder, stirring for 1 hour until the feeding medicinal powder and the hot-melt pressure-sensitive adhesive liquid are fully mixed to obtain a mixture, and keeping the temperature of the obtained mixture to 60 ℃ to obtain an adhesive plaster;
(3) coating: starting a coating machine, preheating for 20 minutes, injecting the adhesive plaster into the coating machine by using a pump for pre-coating, adjusting the amount of the coated adhesive plaster according to requirements until the amount meets the standard requirements, and keeping coating to obtain a coated coiled material;
(4) slicing: placing the coated coiled material obtained in the step (3) for 24 hours, and slicing the coated coiled material by using a splitting machine to obtain a paste paster;
(5) subpackaging: filling the paste paster into a clean inner bag, then sealing, filling an outer box and boxing according to requirements to obtain a finished product;
the size of the paste patch is 9cm multiplied by 13cm, and the amount of the paste coated on each paste patch is 3 g;
the amount of the hot-melt pressure-sensitive adhesive is 4900 parts.
2. A Miao medicine prostate paste as claimed in claim 1, which is characterized in that: the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 250 parts of Tou Gu Xiang 170, 170 parts of Jiu Jie tea 130, 90-130 parts of pyrrosia lingua, 80-120 parts of Japanese climbing fern spore, 80-130 parts of semen plantaginis, 90-140 parts of salted phellodendron, 80-130 parts of astragalus, 90-130 parts of epimedium, 90-140 parts of achyranthes root and 30-60 parts of amber.
3. The Miao medicine prostate paste according to claim 1, characterized in that: the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 220 parts of Touhua Persicolor herb 180, 160 parts of sarcandra glabra 140, 90-110 parts of pyrrosia lingua, 90-120 parts of climbing fern spore, 80-110 parts of semen plantaginis, 90-120 parts of salted cortex phellodendri, 95-115 parts of radix astragali, 95-105 parts of herba Epimedii, 90-115 parts of radix Achyranthis bidentatae and 40-55 parts of amber.
4. The Miao medicine prostate paste according to claim 3, characterized in that: the Miao medicine prostate paste is prepared from the following raw materials in parts by weight: 200 parts of Tou Gu Xiang, 150 parts of sarcandra glabra, 100 parts of pyrrosia lingua, 100 parts of spora lygodii, 100 parts of semen plantaginis, 100 parts of salted golden cypress, 100 parts of radix astragali, 100 parts of herba epimedii, 100 parts of radix achyranthis bidentatae and 50 parts of amber.
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1114582A (en) * 1995-06-19 1996-01-10 张洪斌 Chinese proprietary medicine for curing prostatosis
CN1814148A (en) * 2005-12-05 2006-08-09 杨雄志 Chinese medicine composition for treating prostatitis and use thereof
CN1931292A (en) * 2006-09-18 2007-03-21 曹耘 Medicine for treating urinary system diseases and its quality control method
CN101884718A (en) * 2010-07-10 2010-11-17 孙一凡 Medicament for treating prostatitis
CN102188524A (en) * 2011-05-10 2011-09-21 孙文杰 Pharmaceutical for treating prostatitis and preparation method thereof
CN104906464A (en) * 2015-06-19 2015-09-16 徐延凯 Plaster for treating BPH (Benign Prostate Hyperplasia)
CN109954121A (en) * 2018-11-20 2019-07-02 贵州云上苗家康养有限公司 A kind of Miao ethnic group's external application bubble foot medicine and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103705783A (en) * 2014-01-07 2014-04-09 王先忠 Traditional Chinese medicine composition for treating frequent urination, urgent urination and painful urination caused by hyperplasia of prostate

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1114582A (en) * 1995-06-19 1996-01-10 张洪斌 Chinese proprietary medicine for curing prostatosis
CN1814148A (en) * 2005-12-05 2006-08-09 杨雄志 Chinese medicine composition for treating prostatitis and use thereof
CN1931292A (en) * 2006-09-18 2007-03-21 曹耘 Medicine for treating urinary system diseases and its quality control method
CN101884718A (en) * 2010-07-10 2010-11-17 孙一凡 Medicament for treating prostatitis
CN102188524A (en) * 2011-05-10 2011-09-21 孙文杰 Pharmaceutical for treating prostatitis and preparation method thereof
CN104906464A (en) * 2015-06-19 2015-09-16 徐延凯 Plaster for treating BPH (Benign Prostate Hyperplasia)
CN109954121A (en) * 2018-11-20 2019-07-02 贵州云上苗家康养有限公司 A kind of Miao ethnic group's external application bubble foot medicine and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
中药外敷治疗慢性前列腺炎45例;孙增才等;《河南中医》;20060710;第26卷(第07期);第24页左栏第 *
前愈拆方对大鼠前列腺炎模型组织形态的改变;赵利军等;《中国医院药学杂志》;20070518;第27卷(第05期);第604页左栏第1段,右栏第2段 *
自拟清利化瘀散治疗慢性前列腺炎86例;和剑全;《中国民族民间医药》;20090930(第18期);第17页左栏第1-5段 *

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