CN110193042A - A kind of external application medicine composition that treating synovitis and its preparation process - Google Patents

A kind of external application medicine composition that treating synovitis and its preparation process Download PDF

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CN110193042A
CN110193042A CN201910520560.2A CN201910520560A CN110193042A CN 110193042 A CN110193042 A CN 110193042A CN 201910520560 A CN201910520560 A CN 201910520560A CN 110193042 A CN110193042 A CN 110193042A
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parts
preparation process
external application
raw material
medicine composition
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郭珈宜
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention provides a kind of external application medicine composition for treating synovitis and its preparation processes, and the external application medicine composition of the treatment synovitis is to be made of raw material from the following weight: 28-35 parts of medicine olibanum, 25-35 parts of myrrh, 35-40 parts of rheum officinale and 35-40 parts of Cortex Phellodendri;Its preparation process is the following steps are included: weigh medicine olibanum, myrrh, rheum officinale and Cortex Phellodendri according to parts by weight;The raw material for taking step 1 to obtain are placed in pulverizer, and mixing, which is placed in micronizer, to be crushed, and herb powder is taken out to obtain after crushing, spare;The raw material powder that step 2 is obtained is reconciled using honey, then carries out preparation.A kind of external application medicine composition for treating synovitis provided by the invention and its preparation process, preparation process is simple, and production cost is low, olibanum, myrrh, rheum officinale, Cortex Phellodendri are mixed and made into powder, the mutual compatibility of mixed-powder has activating microcirculation and removing stasis medicinal, warming and activating meridian, the effect of swelling and pain relieving.

Description

A kind of external application medicine composition that treating synovitis and its preparation process
Technical field
The present invention relates to field of traditional Chinese medicine preparation, in particular to a kind of external application medicine composition for treating synovitis and its preparation works Skill.
Background technique
Osteoarthritic Synovium inflammation is the public health problem of global facing.Epidemiology shows, China's osteoarthritis The illness rate of synovitis is in 5.4%-30.5%.This be apt to occur in middle-older patient, especially long campaigns physical work person and from Body overweight people.There is pain and merge articulate moving obstacle in Bones and joints, and clinical manifestation is Bones and joints swelling, pain, hydrops, bends Knee limitation of activity, notably visible amyotrophia, anchylosis, have the characteristics that course of disease length, weak curative effect, Yi Fanfu tri- are big.The sickly look is easy Lead to chronic disability, influences the quality of life of middle-older patient.Currently, doctor trained in Western medicine is generally using oral non_steroidal anti_inflammatory drug And joint cavity injection, method is more single, and not only uncertain therapeutic efficacy is cut, and treatment cost is high, and recurrence rate after palliative, treatment It is higher.
Summary of the invention
To solve the problems mentioned in the above background technology, the outer of synovitis is treated the purpose of the present invention is to provide a kind of Topical application of drug formula and its preparation process, formula is simple, and preparation process is simple, and production cost is low.
In order to solve the above technical problems, technical solution provided by the invention are as follows:
A kind of external application medicine composition that treating synovitis and its preparation process, the external application medicine composition of the treatment synovitis are It is made of raw material from the following weight: 28-35 parts of medicine olibanum, 25-35 parts of myrrh, 35-40 parts of rheum officinale and 35-40 parts of Cortex Phellodendri;
Its preparation process the following steps are included:
1) medicine olibanum, myrrh, rheum officinale and Cortex Phellodendri are weighed according to parts by weight;
2) raw material for taking step 1 to obtain are placed in pulverizer, and mixing, which is placed in micronizer, to be crushed, powder Herb powder is taken out to obtain after broken, it is spare;
3) raw material powder for obtaining step 2 is reconciled using honey, then carries out preparation.
As an improvement, the medicine for external application formula material quality of the treatment synovitis is preferably 30 parts of medicine olibanum, myrrh 30 Part, 40 parts of rheum officinale and 40 parts of Cortex Phellodendri.
As an improvement, the honey is to be slowly added in step 3), raw material powder is modulated into paste.
The beneficial effects of the present invention are:
A kind of external application medicine composition for treating osteoarthritic synovium inflammation provided by the invention can effectively treat primary, secondary bone Arthrosynovitis, shows as that arthralgia, joint part swelling, hydrops, anchylosis, joint stuffiness, tongue is dim-purple or has the stasis of blood The diseases significant effect such as spot, white and greasy fur, stringy and hesitant pulse has the effect of activating microcirculation and removing stasis medicinal, warming and activating meridian, swelling and pain relieving.Of the invention Preparation process is simple, and production cost is low, and olibanum, myrrh, rheum officinale, Cortex Phellodendri are mixed and made into powder, and the mutual compatibility of mixed-powder has Drug effect performance effect is aobvious after activating microcirculation and removing stasis medicinal, warming and activating meridian, the effect of swelling and pain relieving, and these powder are externally applied to Bones and joints skin It writes, and is avoided that in high temperature decoction process that effective component is lost, make the liniment bioavilability height being prepared, drug effect more Add significantly, is suitable for popularization and application.
Specific embodiment
Illustrate the present invention with specific embodiment below, is not limitation of the present invention.
Embodiment one
A kind of external application medicine composition that treating synovitis and its preparation process, the external application medicine composition of the treatment synovitis are It is made of raw material from the following weight: 30 parts of medicine olibanum, 30 parts of myrrh, 40 parts of rheum officinale and 40 parts of Cortex Phellodendri;
Its preparation process the following steps are included:
1) medicine olibanum, myrrh, rheum officinale and Cortex Phellodendri are weighed according to parts by weight, weighs method using double and weighs method, i.e., After one operator weighs, another carries out multiple title;
2) raw material for taking step 1) to obtain are placed in pulverizer, and mixing, which is placed in micronizer, to be crushed, Grain takes out to obtain herb powder less than 200 mesh after crushing, spare;
3) raw material powder for obtaining step 2) is reconciled using honey, then carries out preparation, honey is slowly added, and is carried out Stirring, is stirred into paste for raw material.
Preparation after the completion of preparation will smear surrounding first and clean up, 4-8g preparation is then taken to exist when in use Affected part is gently smeared, until absorbing.
Embodiment two
A kind of external application medicine composition that treating synovitis and its preparation process, the external application medicine composition of the treatment synovitis are It is made of raw material from the following weight: 28 parts of medicine olibanum, 33 parts of myrrh, 42 parts of rheum officinale and 40 parts of Cortex Phellodendri;
Its preparation process the following steps are included:
1) medicine olibanum, myrrh, rheum officinale and Cortex Phellodendri are weighed according to parts by weight, weighs method using double and weighs method, i.e., After one operator weighs, another carries out multiple title;
2) raw material for taking step 1) to obtain are placed in pulverizer, and mixing, which is placed in micronizer, to be crushed, Grain takes out to obtain herb powder less than 200 mesh after crushing, spare;
3) raw material powder for obtaining step 2) is reconciled using honey, then carries out preparation, honey is slowly added, and is carried out Stirring, is stirred into paste for raw material.
Preparation after the completion of preparation will smear surrounding first and clean up, 4-8g preparation is then taken to exist when in use Affected part is gently smeared, until absorbing.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (3)

1. a kind of external application medicine composition for treating synovitis and its preparation process, which is characterized in that outside the treatment synovitis Topical application of drug formula is to be made of raw material from the following weight: 28-35 parts of medicine olibanum, 25-35 parts of myrrh, 35-40 parts of rheum officinale and Cortex Phellodendri 35-40 parts;
Its preparation process the following steps are included:
1) medicine olibanum, myrrh, rheum officinale and Cortex Phellodendri are weighed according to parts by weight;
2) raw material for taking step 1) to obtain are placed in pulverizer, and mixing, which is placed in micronizer, to be crushed, and crush knot Herb powder is taken out to obtain after beam, it is spare;
3) raw material powder for obtaining step 2) is reconciled using honey, then carries out preparation.
2. a kind of external application medicine composition for treating synovitis according to claim 1 and its preparation process, which is characterized in that institute The medicine for external application formula material quality for the treatment synovitis stated is preferably 30 parts of medicine olibanum, 30 parts of myrrh, 40 parts of rheum officinale and Cortex Phellodendri 40 Part.
3. a kind of external application medicine composition for treating synovitis according to claim 1 and its preparation process, which is characterized in that In step 3), the honey is to be slowly added, and raw material powder is modulated into paste.
CN201910520560.2A 2019-06-17 2019-06-17 A kind of external application medicine composition that treating synovitis and its preparation process Withdrawn CN110193042A (en)

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CN201910520560.2A CN110193042A (en) 2019-06-17 2019-06-17 A kind of external application medicine composition that treating synovitis and its preparation process

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Application Number Priority Date Filing Date Title
CN201910520560.2A CN110193042A (en) 2019-06-17 2019-06-17 A kind of external application medicine composition that treating synovitis and its preparation process

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406548A (en) * 2008-11-26 2009-04-15 宋文彬 Chinese medicine preparation for treating arthromeningitis and preparation technique
CN102670895A (en) * 2011-03-11 2012-09-19 邴守兰 Chinese medicinal composition for treating joint traumatic synovitis and preparation method thereof
CN103169822A (en) * 2013-04-17 2013-06-26 宁夏张氏回医正骨医院 Synovitis hui-nationality ointment and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406548A (en) * 2008-11-26 2009-04-15 宋文彬 Chinese medicine preparation for treating arthromeningitis and preparation technique
CN102670895A (en) * 2011-03-11 2012-09-19 邴守兰 Chinese medicinal composition for treating joint traumatic synovitis and preparation method thereof
CN103169822A (en) * 2013-04-17 2013-06-26 宁夏张氏回医正骨医院 Synovitis hui-nationality ointment and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李进京: ""综合疗法治疗膝关节滑膜炎53例", 《河南中医学院学报》 *
罗世东 等: "中药外治膝关节创伤性滑膜炎93例", 《新中医》 *

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Application publication date: 20190903