CN110183501A - A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. - Google Patents
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. Download PDFInfo
- Publication number
- CN110183501A CN110183501A CN201910435328.9A CN201910435328A CN110183501A CN 110183501 A CN110183501 A CN 110183501A CN 201910435328 A CN201910435328 A CN 201910435328A CN 110183501 A CN110183501 A CN 110183501A
- Authority
- CN
- China
- Prior art keywords
- gastrodin
- gastrodia
- wild
- spray
- extracting method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
- C07H1/08—Separation; Purification from natural products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to technical field of plant extraction, more particularly, to a kind of extracting method of wild Gastrodin in Gastrodia eleta Bl..Advantage is: the present invention carries out the extraction of Gastrodin using the high wild Rhizoma Gastrodiae of gastrodin content, Wild gastrodia is because containing more medicinal ingredient, that is gastrodin, Rhizoma Gastrodiae ether glucoside vanillyl alcohol, its peat-reek be artificial cultivation cannot ratio, especially in the persistence of smell, after common Rhizoma Gastrodiae lays out a period of time on sales counter, substantially taste cannot be snuffed, but wild is just different, even if after being dried for a period of time for a long time, it is able to maintain for a long time without subsiding, it can guarantee the extracted amount of Gastrodin, while the ethanol solution by configuring reasonable concentration, Gastrodin is dissolved under appropriate circumstances, then it is spray-dried under high vacuum environment, so that the paste-forming rate of Gastrodin increases, and integrated operation difficulty is lower, extraction efficiency is higher.
Description
Technical field
The invention belongs to technical field of plant extraction, more particularly, to a kind of extracting method of wild Gastrodin in Gastrodia eleta Bl..
Background technique
Gastrodin this product is that the dry root block of orchid Rhizoma Gastrodiae extracts, and the places of origin of raw materials is Yunnan.Gastrodin has preferable
Calmness and soporific function, have relaxation effect to neurasthenia, insomnia, headache syndromes.Gastrodia elata can treat pain dizziness, limbs
Numb, frightened pain is twitched.Clinical application: treatment one basilar artery insufficiency of vertebra；Treat vestibular neuronitis；Treat vertigo.
Wild gastrodia is a kind of rare rare medicinal plant, for treating hypertension, headache and dizziness, facial paralysis, extremity numbness, small
Diseases, the stem tubers such as youngster's convulsions are the good medicine of suppressing hyperactive liver for calming endogenous wind.Wild gastrodia is because containing more medicinal ingredient, i.e. gastrodin, Rhizoma Gastrodiae ether
Glucoside vanillyl alcohol.Its peat-reek be artificial cultivation cannot ratio, especially in the persistence of smell, common Rhizoma Gastrodiae is in cabinet
After laying out a period of time on platform, taste, but wild just difference cannot be snuffed substantially, even if for a long time one section after being dried
Time is able to maintain for a long time without subsiding.
The traditional handicraft for extracting Gastrodin at present mainly has: alcohol extracting method, microwave loss mechanisms, ultrasonic extraction, enzyme extract
And means of supercritical extraction etc..Common problem is mainly that the paste-forming rate of Gastrodin extraction is lower, and product produces in the prior art
Content is lower out, while Processes and apparatus condition is complex, is unfavorable for the operation of amplification production and the control of cost.
For this purpose, it is proposed that a kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. solves the above problems.
Summary of the invention
Regarding the issue above, the present invention provides a kind of rapidly extracting and the high wild Gastrodin in Gastrodia eleta Bl. of paste-forming rate
Extracting method.
In order to achieve the above objectives, present invention employs following technical proposals: a kind of extracting method of open country Gastrodin in Gastrodia eleta Bl.,
Characterized by comprising the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 11-13 times of 40% ethanol solution by S3；
S4 is heated to 60-80 degrees Celsius of increase rate of dissolution；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5-6 obtains medical fluid；
S8 reduces temperature to 20-30 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion.
Steam after the spray drying is collected, and is spray-dried under a high vacuum again after condensation, is repeated 2-3 times
Operation.
Compared with prior art, the advantages of extracting method of this open country Gastrodin in Gastrodia eleta Bl., is:
1, the present invention extracts Gastrodin using Wild gastrodia, the gastrodin content in Wild gastrodia
It is larger, it is hereby achieved that more Gastrodin, has on paste-forming rate and is greatly improved,
And using the ethanol solution of 40% concentration as solvent, so that the dissolution filter of Gastrodin is big
It is big to increase, so that whole improve the extraction rate of Gastrodin.
2, the method that the present invention uses temperature auxiliary simultaneously, according to the property of Gastrodin,
Suitable temperature is dissolved, and further guarantees dissolution rate, further increases paste-forming rate.
3, the method that is spray-dried under the present invention is when extracting Gastrodin using high vacuum, can be with
Second alcohol and water is effectively removed, guarantees the purity of the Gastrodin lotion extracted, improves entirety
The quality of extraction, while entire extraction operation is relatively simple, facilitates and is operated, is needed
Cost is relatively low.
Specific embodiment
Following embodiment only exists in illustrative purpose, limits the scope of the invention without being intended to.
Embodiment 1
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 11 times of 40% ethanol solution by S3；
S4 is heated to 60 degrees Celsius of increase rate of dissolutions；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5 obtains medical fluid；
S8 reduces temperature to 20 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion, institute
Steam after stating spray drying is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Embodiment 2
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 11.4 times of 40% ethanol solution by S3；
S4 is heated to 64 degrees Celsius of increase rate of dissolutions；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5.2 obtains medical fluid；
S8 reduces temperature to 22 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion, institute
Steam after stating spray drying is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Embodiment 3
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 11.8 times of 40% ethanol solution by S3；
S4 is heated to 68 degrees Celsius of increase rate of dissolutions；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5.4 obtains medical fluid；
S8 reduces temperature to 24 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion, institute
Steam after stating spray drying is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Embodiment 4
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 12.2 times of 40% ethanol solution by S3；
S4 is heated to 72 degrees Celsius of increase rate of dissolutions；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5.6 obtains medical fluid；
S8 reduces temperature to 26 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion, institute
Steam after stating spray drying is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Embodiment 5
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 12.6 times of 40% ethanol solution by S3；
S4 is heated to 76 degrees Celsius of increase rate of dissolutions；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5.8 obtains medical fluid；
S8 reduces temperature to 28 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion, institute
Steam after stating spray drying is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Embodiment 6
A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 13 times of 40% ethanol solution by S3；
S4 is heated to 80 degrees Celsius of increase rate of dissolutions；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 6 obtains medical fluid；
S8 reduces temperature to 30 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion, spray
Steam after mist is dry is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Claims (2)
1. a kind of extracting method of open country Gastrodin in Gastrodia eleta Bl., which comprises the following steps:
Wild gastrodia is cleaned stripping and slicing by S1；
S2 weighs quantitative stripping and slicing and smashs to pieces, pulverizes spare；
The grounds travel of upper step is dissolved in 11-13 times of 40% ethanol solution by S3；
S4 is heated to 60-80 degrees Celsius of increase rate of dissolution；
S5, heat preservation while, carry out stewing process；
S6 is filtered operation, filters out residue and leaves filtrate；
While heat preservation, ammonium hydroxide alkalization is added into the filtrate obtained by S7, and adjustment pH value to 5-6 obtains medical fluid；
S8 reduces temperature to 20-30 degrees Celsius, medical fluid is spray-dried under a high vacuum, obtains Gastrodin lotion.
2. the extracting method of open country Gastrodin in Gastrodia eleta Bl. according to claim 1, which is characterized in that after the spray drying
Steam is collected, and is spray-dried under a high vacuum again after condensation, and 2-3 operation is repeated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910435328.9A CN110183501A (en) | 2019-05-23 | 2019-05-23 | A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910435328.9A CN110183501A (en) | 2019-05-23 | 2019-05-23 | A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110183501A true CN110183501A (en) | 2019-08-30 |
Family
ID=67717582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910435328.9A Pending CN110183501A (en) | 2019-05-23 | 2019-05-23 | A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110183501A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112812144A (en) * | 2021-03-26 | 2021-05-18 | 贵州高山生物科技有限公司 | Method for extracting gastrodin extract |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108409808A (en) * | 2018-05-31 | 2018-08-17 | 中山大学 | A kind of method of the broken extraction Gastrodin in Gastrodia eleta Bl. of continuous low-temperature high pressure |
-
2019
- 2019-05-23 CN CN201910435328.9A patent/CN110183501A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108409808A (en) * | 2018-05-31 | 2018-08-17 | 中山大学 | A kind of method of the broken extraction Gastrodin in Gastrodia eleta Bl. of continuous low-temperature high pressure |
Non-Patent Citations (3)
| Title |
|---|
| 刘明海: "野生天麻与种植天麻的主要性状鉴别与质量比较", 《中国药业》 * |
| 国家食品药品监督管理局执业药师资格认证中心: "《中药学专业知识.1》", 31 January 2014, 中国医药科技出版社 * |
| 田洋等: "天麻中天麻素RP-HPLC测定及提取工艺研究", 《食品科学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112812144A (en) * | 2021-03-26 | 2021-05-18 | 贵州高山生物科技有限公司 | Method for extracting gastrodin extract |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103451022A (en) | Method for integrally extracting volatile oil, polysaccharide and flavone from elsholtzia haichowensis sun | |
| KR101603294B1 (en) | Ginsenoside extract method from the damaged wild ginseng | |
| CN102453601B (en) | Extraction method of Cinnamomum camphora seed oil by ultrasound-assisted compound enzyme | |
| CN105622777A (en) | Technology for extracting pectin from premna microphylla turca | |
| CN103087548B (en) | Method for extracting trichosanthes kirilowii maxim uranidin | |
| KR101341755B1 (en) | The effective isolation method of panaxadiol saponin fraction from ginseng using pectinase | |
| CN104623095A (en) | Extraction method for FructusLycii active ingredient | |
| KR20100043725A (en) | Changes of protopanaxadiol ginsenosides in ginseng leaves by steaming heat treatment | |
| CN104450172A (en) | Fructussilybi oil extraction method | |
| CN104087420A (en) | Subcritical extraction method capable of improving antioxidant activity of volatile oil in agarwood leaves | |
| Tang et al. | Optimization of the technology of extracting water-soluble polysaccharides from Morus alba L. leaves | |
| CN110183501A (en) | A kind of extracting method of open country Gastrodin in Gastrodia eleta Bl. | |
| CN103830292A (en) | Apocynum flavonoid extract and preparation method thereof | |
| KR101785482B1 (en) | Preparation method for fermented ginseng berry extract, nutraceutical composition and cosmetic compostion using the same | |
| CN105238611A (en) | Persimmon-leaf health-care wine containing dried scallop and south chrysanthemum stems and leaves and preparation method of persimmon-leaf health-care wine | |
| CN104435194A (en) | Extraction method of berberine | |
| CN104945450B (en) | A kind of method that Stibene-glucoside is extracted from the vine of multiflower knotweed | |
| CN110699180A (en) | Preparation method of abelmoschus manihot tobacco flavor | |
| KR20100043723A (en) | Changes of protopanaxadiol ginsenosides in ginseng leaves by far infrared heat treatment | |
| CN104069135A (en) | Process for extracting cacumen biotae general flavone | |
| CN104086615A (en) | Method for preparing mogroside V from siraitia grosvenori | |
| CN106667857A (en) | Preparation method of white Chinese floweringquince extract for facial mask through microwave-assisted extraction | |
| CN105532350A (en) | Preparation method of ilex hainanensis and ginkgo extract composite tea | |
| CN105477459A (en) | Maian granules and preparation method thereof | |
| KR20190017532A (en) | The red ginseng's functionality using the fields and reef fermented liquor manufacturing methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190830 |