CN110179962A - A kind of Chinese materia medica preparation and preparation method thereof for treating gynecology colpitis - Google Patents

A kind of Chinese materia medica preparation and preparation method thereof for treating gynecology colpitis Download PDF

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CN110179962A
CN110179962A CN201910631913.6A CN201910631913A CN110179962A CN 110179962 A CN110179962 A CN 110179962A CN 201910631913 A CN201910631913 A CN 201910631913A CN 110179962 A CN110179962 A CN 110179962A
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preparation
parts
materia medica
chinese materia
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伍思荣
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Beijing Danxi Institute Of Traditional Chinese Medicine
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Beijing Danxi Institute Of Traditional Chinese Medicine
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention belongs to Chinese medicine and its preparation technical fields, disclose a kind of Chinese materia medica preparation and preparation method thereof for treating gynecology colpitis.The Chinese materia medica preparation is by the way that the fresh medicinal material taken and conventional drying medicinal material is mixture prepared with the proportion for being suitable for.The effect of each medicinal material complements each other in the Chinese materia medica preparation, strengthens the mutual fusion between each medicinal material, reaches clearing damp middle benefit gas, anti inflammation and heat resolution, recover Yang and smooth venation, eliminating dampness dissolving phlegm and eliminating cold to stop pain.Under the mating reaction of all kinds of medicinal materials, the temperature in uterus to vagina is effectively promoted, improves gynaecologic vaginal growth of probiotics environment, promotes the breeding of vagina probiotics, achievees the purpose that treat vaginitis from the root.The preparation method of the Chinese materia medica preparation is while the nutritional ingredient and medicinal ingredient for saving medicinal material itself to the maximum extent, it is simple to operation, it is few to operate equipment, it is low in cost, securely and reliably, it is without any side effects, it is adhered to always in medicinal material collection process and maintains ecological balance principle, the individual suitable for each age group.

Description

A kind of Chinese materia medica preparation and preparation method thereof for treating gynecology colpitis
Technical field
The invention belongs to traditional Chinese medicine and its preparation technical fields, and in particular to a kind of for treating the Chinese medicine of gynecology colpitis Preparation and preparation method thereof.
Background technique
Vaginitis is women's common frdquently encountered disease, is to lead to vulvovaginal symptom such as itch, cusalgia, stimulation and abnormal flow liquid One group of illness.Vaginitis includes nonspecific vaginitis, vulvitis, colpomycosis, trichomonas vaginitis etc..It is normal strong The characteristics of health woman vagina is due to anatomical structure has natural defense function to the intrusion of pathogen.Such as the closure of introitus, vagina Front and rear wall is close to, hyperplasia and cells of superficial layer angling of the vaginal epithelial cell under the influence of estrogen, and vagina acid-base degree keeps flat Weighing apparatus is suppressed the breeding of pathogen for adapting to alkalinity, and neck tube mucus is in alkalinity, when vagina natural defense function by When destruction, pathogen is easy to invade, and leads to colpitis.
According to statistics, carcinoma of vulva accounts for 40% by what vulvitis developed, mostly occurs in middle aged and aged women, gives women after the onset Bring painful topic, and easily superinfection, most touching refractory, the serious quality of life for affecting women of the course of disease.Normally In the case of there is aerobic bacteria and anaerobic bacteria to reside in intravaginal, form normal vaginal flora.Any reason by vagina and flora it Between the ecological balance break, can also formation condition pathogenic bacteria.It is clinically common to have: bacterial vaginosis BV, monilial vaginitis, Trichomonas vaginitis, senile vahinitis and infantile vaginitis etc..
The treatment method of traditional doctor trained in Western medicine is exactly including oral antibiotic, intravenous antibiotics anti-inflammatory, to be washed based on antibacterial Liquid flushing and internal plug antibiotic suppository etc..Often user's body can be made to develop drug resistance after above-mentioned western medical treatment, be easy inflammation repeatedly, and And serious destruction growth of probiotics environment, so that water mo(u)ld, candida albicans, mycoplasma and Chlamydia etc. is lost primary natural enemy, to make The immunity of organisms of user is remarkably decreased.
Summary of the invention
In order to solve the above problems existing in the present technology, it is an object of that present invention to provide one kind for treating gynaecologic vaginal Scorching Chinese materia medica preparation and preparation method thereof.
The technical scheme adopted by the invention is as follows: a kind of for treating the Chinese materia medica preparation of gynecology colpitis, the Chinese materia medica preparation Mainly it is prepared by the raw material of following mass fraction:
30-200 parts of smilax, 20-120 parts of honeysuckle, 30-100 parts of Radix Angelicae Sinensis, 20-90 parts of Radix Paeoniae Alba, 30-100 parts of Radix Astragali, 30-100 parts of Rhizoma Chuanxiong, 0.5-10 parts of rhizoma zingiberis and 0.1-3 parts of monkshood.
Preferably, which is mainly prepared by the raw material of following mass fraction:
80-150 parts of smilax, 40-80 parts of honeysuckle, 40-80 parts of Radix Angelicae Sinensis, 30-80 parts of Radix Paeoniae Alba, 50-80 parts of Radix Astragali, Rhizoma Chuanxiong 45-80 parts, 2-5 parts of rhizoma zingiberis and 0.8-2 parts of monkshood.
Preferably, which is mainly prepared by the raw material of following mass fraction:
120 parts of smilax, 60 parts of honeysuckle, 50 parts of Radix Angelicae Sinensis, 45 parts of Radix Paeoniae Alba, 60 parts of Radix Astragali, 55 parts of Rhizoma Chuanxiong, 3 parts of rhizoma zingiberis and 1 part of monkshood.
The Chinese materia medica preparation for being used to treat gynecology colpitis provided by the invention is by by the fresh medicinal material taken and often Rule drying medicinal material is mixture prepared with suitable proportion.Each medicinal material monarch compatibility in the Chinese materia medica preparation is proper, phase It is auxiliary to coordinate, substantially enhance the effect that Xiang Zuoxiang is helped, mutually merged between each medicinal material, thus reach clearing damp middle benefit gas, yin and blood nourishing, The effect of anti inflammation and heat resolution, recover Yang and smooth venation, eliminating dampness dissolving phlegm and eliminating cold to stop pain.Meanwhile under the mating reaction of all kinds of medicinal materials, effectively mention The temperature for having risen uterus to vagina improves gynaecologic vaginal growth of probiotics environment, promotes the breeding of vagina probiotics, to treatment Vaginitis has high curative effect, significantly improves cure rate, achievees the purpose that treat vaginitis from the root.
It is a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, which includes the following steps:
(1) slurrying: smilax is weighed according to corresponding proportion and honeysuckle adds water filter after being crushed slurrying, is obtained primary Reserve liquid
(2) infusion and filter: being weighed after Radix Angelicae Sinensis, Radix Paeoniae Alba, Radix Astragali, Rhizoma Chuanxiong, rhizoma zingiberis and monkshood mixing according to corresponding proportion plus Solvent impregnated, infusion and is filtered, and obtains secondary reserve liquid after cooling;
(3) stand: the reserve liquid that step (1) is obtained is mixed simultaneously with the secondary reserve liquid that step (2) obtains It stands after mixing evenly, obtains reserve liquid three times;
(4) finished product is made: finished product will be obtained after the filtering of reserve liquid three times in step (3).
The operating process of the preparation method of the Chinese materia medica preparation provided by the invention is simple and direct, and operation equipment is few, to operator It is of less demanding and low in cost.The Chinese materia medica preparation is safe and reliable, without any side effects, adheres to dimension in medicinal material collection process always The principle holding the ecological balance, conserving natural habitats, the individual suitable for each age group.
Preferably, amount of water and weighed medicinal material total quality ratio are 35-180:5-18 when step (1) slurrying;
Preferably, amount of water and weighed medicinal material total quality ratio are 56-140:8-14 when slurrying;
It is further preferred that amount of water and weighed medicinal material total quality ratio are 70-120:10-12 when slurrying.
Preferably, step (1) mixing time is 5-35 minutes;
Preferably, mixing time is 10-30 minutes;
It is further preferred that mixing time is 15-25 minutes.
Preferably, the screen of 100-280 mesh is selected after step (1) slurrying;
Preferably, the screen of 140-220 mesh is selected after slurrying;
It is further preferred that selecting the screen of 180-200 mesh after slurrying.
Provided by the invention this be used to treat the Chinese materia medica preparation of gynecology colpitis by early period to smilax and honeysuckle It selects the mode of slurrying to obtain reserve liquid, is to make medicinal material itself on to greatest extent for when taking fresh feed Nutritional ingredient is saved with medicinal ingredient, also effectively reduce medicinal material dry preparation, store for future use and use process in have Imitate the loss of ingredient.Reserve liquid is filtered after time and slurrying for slurrying, be for promote in medicinal material it is medicinal at Get sufficiently precipitation, residue is removed, mouthfeel is taken in increase, is promoted and merges into each other degree between drug.
Preferably, step (2) institute solubilizer includes water, and amount of water and weighed medicinal material total quality ratio are 180-500:18- 50;
Preferably, amount of water and weighed medicinal material total quality ratio are 220-450:22-46;
It is further preferred that amount of water and weighed medicinal material total quality ratio are 280-350:28-35.
Preferably, the infusion time is 30-75 minutes in step (2);
Preferably, the infusion time is 45-60 minutes;
It is further preferred that the infusion time is 50 minutes.
The Chinese materia medica preparation for being used to treat gynecology colpitis provided by the invention impregnates conventional drying medicinal material, is endured Boil, the setting to amount of water needed for infusion time and infusion, be for raw material obtain sufficiently impregnate after, in the infusion of setting At a temperature of carry out infusion, can to greatest extent reduce energy consumption in the case where, improve raw material in medicinal ingredient amount of precipitation, mention Rise therapeutic effect.
Preferably, the temperature of secondary reserve liquid after cooling is 15-30 degrees Celsius in step (2);
Preferably, the temperature of secondary reserve liquid after cooling is 20-28 degrees Celsius;
It is further preferred that the temperature of secondary reserve liquid after cooling is 23-25 degrees Celsius.
The Chinese materia medica preparation for being used to treat gynecology colpitis provided by the invention is cooled down after the completion of infusion, is to be used for It reduces and stands and the volatilization of filter process Chinese medicine liquid, while ensure that and can be efficiently separated between medical fluid and waste.
The invention has the benefit that
The invention discloses a kind of Chinese materia medica preparations and preparation method thereof for treating gynecology colpitis.This is used to treat woman The Chinese materia medica preparation of section's vaginitis is by the way that the fresh medicinal material taken and conventional drying medicinal material to be mixed with the proportion for being suitable for It arrives.Each medicinal material monarch compatibility in the Chinese materia medica preparation is proper, complements each other, and substantially enhances Xiang Zuoxiang between each medicinal material The effect help, mutually merged, to reach clearing damp middle benefit gas, yin and blood nourishing, anti inflammation and heat resolution, recover Yang and smooth venation, eliminating dampness dissolving phlegm and cold dispelling The effect of analgesic.Meanwhile under the mating reaction of all kinds of medicinal materials, the temperature in uterus to vagina is effectively improved, gynaecology is improved Vagina growth of probiotics environment promotes the breeding of vagina probiotics, has high curative effect to treatment vaginitis, significantly improves Cure rate achievees the purpose that treat vaginitis from the root.The preparation method of the Chinese materia medica preparation is saving medicine to the maximum extent While the nutritional ingredient and medicinal ingredient of material itself, operating process is simple and direct, operation equipment it is few, it is of less demanding to operator and It is low in cost.The Chinese materia medica preparation is safe and reliable, without any side effects, adheres to the maintenance ecological balance in medicinal material collection process always Principle, the individual suitable for each age group.
Specific embodiment
Further explaination is done to the present invention combined with specific embodiments below.It will be understood to those of skill in the art that following institute The embodiment of description is that a part of the embodiment of the present invention is merely to illustrate the present invention instead of all the embodiments, without that should regard To limit the scope of the invention.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creative labor Every other embodiment obtained under the premise of dynamic, shall fall within the protection scope of the present invention.Actual conditions are not specified in embodiment Person carries out according to normal conditions.Agents useful for same is the conventional products that can be obtained by commercially available purchase.
The present invention is added during actual fabrication in the specific implementation process in order to promote mouthfeel when patient takes Natural sweetener, including honey, sucrose, granulated sugar etc..The type and addition Chinese medicine provided by the invention of above-mentioned natural sweetener Dosage in preparation, patient can select according to the actual conditions of itself, while the natural sweetener has no effect on the present invention The healing curative effect of the Chinese materia medica preparation of offer.
Embodiment 1:
30 grams and 20 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 350 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 5 minutes 100 mesh screens are crossed afterwards, obtain a reserve liquid.It chooses and weighs 30 grams of Radix Angelicae Sinensis, 20 grams of Radix Paeoniae Alba, 30 grams of Radix Astragali, 30 grams of Rhizoma Chuanxiong, do It is put into container after 0.5 gram and 0.5 gram of monkshood mixing of ginger, 1106 grams of water is added into container and impregnate, are carried out after impregnating 30 minutes Infusion crosses 150 mesh screens, filtrate is cooled to 15 degrees Celsius later, obtains secondary reserve liquid to boiling after infusion 30 minutes.It will Reserve liquid and secondary reserve liquid stand 5 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To be spare three times Liquid crosses 200 mesh screens, obtains finished product.
Embodiment 2:
30 grams and 20 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 3200 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 35 divides 280 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 30 grams of Radix Angelicae Sinensis, 20 grams of Radix Paeoniae Alba, 30 grams of Radix Astragali, 30 grams of Rhizoma Chuanxiong, It is put into container after 0.5 gram and 0.5 gram of monkshood mixing of rhizoma zingiberis, 4050 grams of water is added into container and impregnate, immersion 70 minutes laggard Row infusion crosses 600 mesh screens, filtrate is cooled to 30 degrees Celsius later, obtains secondary reserve liquid to boiling after infusion 75 minutes. 15 minutes are stood after reserve liquid and secondary reserve liquid be mixed and stirred for uniformly, obtains reserve liquid three times.It will three times Reserve liquid crosses 800 mesh screens, obtains finished product.
Embodiment 3:
200 grams and 120 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 350 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 5 minutes 100 mesh screens are crossed afterwards, obtain a reserve liquid.Choose and weigh 100 grams of Radix Angelicae Sinensis, 90 grams of Radix Paeoniae Alba, 100 grams of Radix Astragali, Rhizoma Chuanxiong 100 Gram, be put into container after 10 grams of rhizoma zingiberis and 3 grams of monkshood mixing, 1106 grams of water are added into container and impregnate, impregnate 30 minutes it is laggard Row infusion crosses 150 mesh screens, filtrate is cooled to 15 degrees Celsius later, obtains secondary reserve liquid to boiling after infusion 30 minutes. 5 minutes are stood after reserve liquid and secondary reserve liquid be mixed and stirred for uniformly, obtains reserve liquid three times.To be standby three times 200 mesh screens are crossed with liquid, obtain finished product.
Embodiment 4:
200 grams and 120 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 3200 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 35 divides 280 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 100 grams of Radix Angelicae Sinensis, 90 grams of Radix Paeoniae Alba, 100 grams of Radix Astragali, Rhizoma Chuanxiong 100 Gram, be put into container after 10 grams of rhizoma zingiberis and 3 grams of monkshood mixing, 4050 grams of water are added into container and impregnate, impregnate 70 minutes it is laggard Row infusion crosses 600 mesh screens, filtrate is cooled to 30 degrees Celsius later, obtains secondary reserve liquid to boiling after infusion 75 minutes. 15 minutes are stood after reserve liquid and secondary reserve liquid be mixed and stirred for uniformly, obtains reserve liquid three times.It will three times Reserve liquid crosses 800 mesh screens, obtains finished product.
Embodiment 5:
80 grams and 40 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 840 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 10 divides 140 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 40 grams of Radix Angelicae Sinensis, 30 grams of Radix Paeoniae Alba, 50 grams of Radix Astragali, 45 grams of Rhizoma Chuanxiong, It is put into container after 2 grams and 0.8 gram of monkshood mixing of rhizoma zingiberis, 1678 grams of water is added into container and impregnate, are carried out after impregnating 50 minutes Infusion crosses 200 mesh screens, filtrate is cooled to 20 degrees Celsius later, obtains secondary reserve liquid to boiling after infusion 45 minutes.It will Reserve liquid and secondary reserve liquid stand 8 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To be spare three times Liquid crosses 450 mesh screens, obtains finished product.
Embodiment 6:
80 grams and 40 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 2300 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 30 divides 220 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 40 grams of Radix Angelicae Sinensis, 30 grams of Radix Paeoniae Alba, 50 grams of Radix Astragali, 45 grams of Rhizoma Chuanxiong, It is put into container after 2 grams and 0.8 gram of monkshood mixing of rhizoma zingiberis, 3270 grams of water is added into container and impregnate, are carried out after impregnating 65 minutes To boiling, 500 mesh screens are crossed in infusion after sixty minutes for infusion, and filtrate is cooled to 28 degrees Celsius later, obtains secondary reserve liquid.It will Reserve liquid and secondary reserve liquid stand 12 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To be standby three times 600 mesh screens are crossed with liquid, obtain finished product.
Embodiment 7:
150 grams and 80 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 840 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 10 divides 140 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 80 grams of Radix Angelicae Sinensis, 80 grams of Radix Paeoniae Alba, 80 grams of Radix Astragali, 80 grams of Rhizoma Chuanxiong, It is put into container after 5 grams and 2 grams of monkshood mixing of rhizoma zingiberis, 1678 grams of water is added into container and impregnate, are endured after impregnating 50 minutes It boils to boiling, 200 mesh screens is crossed after infusion 45 minutes, filtrate is cooled to 20 degrees Celsius later, obtains secondary reserve liquid.By one Secondary reserve liquid and secondary reserve liquid stand 8 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To reserve liquid three times 450 mesh screens are crossed, finished product is obtained.
Embodiment 8:
150 grams and 80 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 2300 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 30 divides 220 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 80 grams of Radix Angelicae Sinensis, 80 grams of Radix Paeoniae Alba, 80 grams of Radix Astragali, 80 grams of Rhizoma Chuanxiong, It is put into container after 5 grams and 2 grams of monkshood mixing of rhizoma zingiberis, 3270 grams of water is added into container and impregnate, are endured after impregnating 65 minutes It boils to boiling, infusion crosses 500 mesh screens after sixty minutes, filtrate is cooled to 28 degrees Celsius later, obtains secondary reserve liquid.By one Secondary reserve liquid and secondary reserve liquid stand 12 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To be spare three times Liquid crosses 600 mesh screens, obtains finished product.
Embodiment 9:
120 grams and 60 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 900 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 15 divides 180 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 50 grams of Radix Angelicae Sinensis, 45 grams of Radix Paeoniae Alba, 60 grams of Radix Astragali, 55 grams of Rhizoma Chuanxiong, It is put into container after 3 grams and 1 gram of monkshood mixing of rhizoma zingiberis, 2140 grams of water is added into container and impregnate, immersion is endured after sixty minutes It boils to boiling, 480 mesh screens is crossed after infusion 50 minutes, filtrate is cooled to 23 degrees Celsius later, obtains secondary reserve liquid.By one Secondary reserve liquid and secondary reserve liquid stand 10 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To be spare three times Liquid crosses 550 mesh screens, obtains finished product.
Embodiment 10:
120 grams and 60 grams of honeysuckle of fresh smilax are taken, small fourth is cut into after smilax cleaning and is put into breaking-wall cell machine In, then honeysuckle is put into breaking-wall cell machine, 1800 grams of water are then added into breaking-wall cell machine and carry out slurrying.Slurrying 25 divides 200 mesh screens are crossed after clock, obtain a reserve liquid.Choose and weigh 50 grams of Radix Angelicae Sinensis, 45 grams of Radix Paeoniae Alba, 60 grams of Radix Astragali, 55 grams of Rhizoma Chuanxiong, It is put into container after 3 grams and 1 gram of monkshood mixing of rhizoma zingiberis, 2140 grams of water is added into container and impregnate, immersion is endured after sixty minutes It boils to boiling, 480 mesh screens is crossed after infusion 50 minutes, filtrate is cooled to 25 degrees Celsius later, obtains secondary reserve liquid.By one Secondary reserve liquid and secondary reserve liquid stand 10 minutes after be mixed and stirred for uniformly, obtain reserve liquid three times.To be spare three times Liquid crosses 550 mesh screens, obtains finished product.
The present invention uses breaking-wall cell machine in pulping process of the specific implementation process to motherwort, the slurrying instrument Selection may also include beater, common soy bean milk making machine etc., and all machinery that can be used for for motherwort being made slurry belong to the present invention The range of protection.
Experimental example
The age is randomly selected between 25-60 years old, hospital is diagnosed as colpomycosis, clinical symptoms are as follows: leucorrhea increasing, There is the patient of the symptoms such as peculiar smell, pruritus vulvue, urine urgency-frequency urodynia as experimental subjects.120 trouble are chosen according to above-mentioned standard Control group is divided into 2 groups wherein 20 experimental subjects are compared group by person, every group of 10 people, and is numbered: first group and Two groups;100 experimental subjects are divided into 10 groups, every group of 10 people make experimental group;Each experimental group and control group correspond.
Take mode: experimental group: above-mentioned 10 groups are numbered: 1-10, each number experimental group, which respectively corresponds, to be taken The Chinese materia medica preparation that above-mentioned 10 kinds of embodiments provided by the invention are prepared.It is taken orally under fasting state, each 350mL is small every 4 When take it is primary.
Control group: first group uses Gyno-Daktarin.Once a night, ten times it is as a treatment course.
Second group uses JIEERYIN XIYE.Vulva is cleaned with the washing lotion of 10% concentration, is sent 10% washing lotion with flusher To vagina deep washing vagina, once a day, seven times as a treatment course.
Testing index: experimental group and control group take one course for the treatment of of corresponding drug respectively, 30 days as a treatment course, Determined after taking by the state that the body to experimental group experimental subjects and control group experimental subjects is presented.
Testing result:
The observation result of the ordinary circumstance of experimental subjects:
The 1st group of experimental subjects is taken embodiment 1, and gained takes effect are as follows: leukorrhea amount is reduced, and peculiar smell mitigates, vulva Pruritis mitigates, and urine urgency-frequency urodynia symptom mitigates, and experimental subjects has no adverse reaction.
The 2nd group of experimental subjects is taken embodiment 2, and gained takes effect are as follows: leukorrhea amount is reduced, and peculiar smell mitigates, vulva Pruritis mitigates, and urine urgency-frequency urodynia symptom mitigates, and experimental subjects has no adverse reaction.
The 3rd group of experimental subjects is taken embodiment 3, and gained takes effect are as follows: leukorrhea reduction amount gradually increases, and peculiar smell persistently subtracts Gently, pruritus vulvue symptom persistently mitigates, and urine urgency-frequency urodynia symptoms last mitigates, and experimental subjects has no adverse reaction.
The 4th group of experimental subjects is taken embodiment 4, and gained takes effect are as follows: leukorrhea reduction amount gradually increases, and peculiar smell persistently subtracts Gently, pruritus vulvue symptom persistently mitigates, and urine urgency-frequency urodynia symptoms last mitigates, and experimental subjects has no adverse reaction.
The 5th group of experimental subjects is taken embodiment 5, and gained takes effect are as follows: and leukorrhea amount significantly reduces, and peculiar smell fades away, Pruritus vulvue symptom is substantially reduced, and urine urgency-frequency urodynia symptom is substantially reduced, and experimental subjects has no adverse reaction.
The 6th group of experimental subjects is taken embodiment 6, and gained takes effect are as follows: and leukorrhea amount significantly reduces, and peculiar smell fades away, Pruritus vulvue symptom is substantially reduced, and urine urgency-frequency urodynia symptom is substantially reduced, and experimental subjects has no adverse reaction.
The 7th group of experimental subjects is taken embodiment 7, and gained takes effect are as follows: leukorrhea amount is less, and peculiar smell disappears, pruritus vulvue Symptom fades away, and urine urgency-frequency urodynia symptom fades away, and experimental subjects has no adverse reaction.
The 8th group of experimental subjects is taken embodiment 8, and gained takes effect are as follows: leukorrhea amount is less, and peculiar smell disappears, pruritus vulvue Symptom fades away, and urine urgency-frequency urodynia symptom fades away, and experimental subjects has no adverse reaction.
The 9th group of experimental subjects is taken embodiment 9, and gained takes effect are as follows: leukorrhea disappears, and peculiar smell disappears, pudendal pruritus Shape disappears, and urine urgency-frequency urodynia symptom disappears, and experimental subjects has no adverse reaction.
The 10th group of experimental subjects is taken embodiment 10, and gained takes effect are as follows: leukorrhea disappears, and peculiar smell disappears, pruritus vulvue Symptom disappears, and urine urgency-frequency urodynia symptom disappears, and experimental subjects has no adverse reaction.
One group is compareed using Gyno-Daktarin, gained takes effect are as follows: leukorrhea disappears, and peculiar smell disappears, and pruritus vulvue symptom disappears It loses, urine urgency-frequency urodynia symptom disappears, but part control group experimental subjects will appear pruritus vulvue again after medication terminates Symptom.
Two groups are compareed using JIEERYIN XIYE, gained takes effect are as follows: leukorrhea disappears, and peculiar smell disappears, pruritus vulvue symptom It disappears, urine urgency-frequency urodynia symptom disappears, but above-mentioned symptom occurs again after medication terminates, and immunity of organisms has It is reduced.
In conclusion the Chinese materia medica preparation of the treatment gynecology colpitis provided by the invention can be obviously improved vagina portion The state of position, the reductions degree of control group and of the invention suitable, body in experimental group experimental subjects healing process and after healing Body in order, has no adverse reaction.Although and control group can be obviously improved the state at vagina position, control group experiment With the presence of adverse reaction after object medication.
Clinical case:
Patient: female suffers from gynaecological imflammation 20 years, is rinsed during one's sickness by oral antibiotic, intravenous injection, washing lotion, is interior The drugs such as turunda bolt cause immunity of organisms to decline, vaginitis exacerbation of symptoms.Using embodiment 10 provided by the invention, patient is allowed It takes, is taken orally under fasting state, each 350mL, taken every 4 hours primary.Treat a course for the treatment of, i.e., patient after one month Immunity of organisms is remarkably reinforced, and the state of mind significantly improves, and vagina position is without other symptoms.Patient continues one treatment of medication later Journey, vaginitis are thoroughly fully recovered.
The invention discloses a kind of Chinese materia medica preparations and preparation method thereof for treating gynecology colpitis.This is used to treat woman The Chinese materia medica preparation of section's vaginitis is by the way that the fresh medicinal material taken and conventional drying medicinal material to be mixed with the proportion for being suitable for It arrives.Each medicinal material monarch compatibility in the Chinese materia medica preparation is proper, complements each other, and substantially enhances Xiang Zuoxiang between each medicinal material The effect help, mutually merged, to reach clearing damp middle benefit gas, yin and blood nourishing, anti inflammation and heat resolution, recover Yang and smooth venation, eliminating dampness dissolving phlegm and cold dispelling The effect of analgesic.Meanwhile under the mating reaction of all kinds of medicinal materials, the temperature in uterus to vagina is effectively improved, gynaecology is improved Vagina growth of probiotics environment promotes the breeding of vagina probiotics, has high curative effect to treatment vaginitis, significantly improves Cure rate achievees the purpose that treat vaginitis from the root.The preparation method of the Chinese materia medica preparation is saving medicine to the maximum extent While the nutritional ingredient and medicinal ingredient of material itself, operating process is simple and direct, operation equipment it is few, it is of less demanding to operator and It is low in cost.The Chinese materia medica preparation is safe and reliable, without any side effects, adheres to the maintenance ecological balance in medicinal material collection process always Principle, the individual suitable for each age group.
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that the present invention is not limited to Optional embodiment is stated, anyone can obtain other various forms of products under the inspiration of the present invention.Above-mentioned specific reality The mode of applying should not be understood the limitation of pairs of protection scope of the present invention, those skilled in the art should understand that, it is not carrying on the back In the case where from the spirit and scope of the present invention, it is possible to modify the technical solutions described in the foregoing embodiments, or Equivalent substitution of some or all of the technical features, these are modified or replaceed at the same time, can't make corresponding The essence of technical solution depart from the scope of the technical solutions of the embodiments of the present invention;Protection scope of the present invention should be wanted with right It asks subject to being defined in book, and specification can be used for interpreting the claims.

Claims (10)

1. a kind of for treating the Chinese materia medica preparation of gynecology colpitis, which is characterized in that the Chinese materia medica preparation is mainly by following quality The raw material of number is prepared:
30-200 parts of smilax, 20-120 parts of honeysuckle, 30-100 parts of Radix Angelicae Sinensis, 20-90 parts of Radix Paeoniae Alba, 30-100 parts of Radix Astragali, Rhizoma Chuanxiong 30-100 parts, 0.5-10 parts of rhizoma zingiberis and 0.1-3 parts of monkshood.
2. according to claim 1 a kind of for treating the Chinese materia medica preparation of gynecology colpitis, which is characterized in that the Chinese medicine Preparation is mainly prepared by the raw material of following mass fraction:
80-150 parts of smilax, 40-80 parts of honeysuckle, 40-80 parts of Radix Angelicae Sinensis, 30-80 parts of Radix Paeoniae Alba, 50-80 parts of Radix Astragali, Rhizoma Chuanxiong 45- 80 parts, 2-5 parts of rhizoma zingiberis and 0.8-2 parts of monkshood.
3. according to claim 2 a kind of for treating the Chinese materia medica preparation of gynecology colpitis, which is characterized in that the Chinese medicine Preparation is mainly prepared by the raw material of following mass fraction:
120 parts of smilax, 60 parts of honeysuckle, 50 parts of Radix Angelicae Sinensis, 45 parts of Radix Paeoniae Alba, 60 parts of Radix Astragali, 55 parts of Rhizoma Chuanxiong, 3 parts of rhizoma zingiberis and monkshood 1 Part.
4. it is according to claim 1 to 3 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, It is characterized in that, the preparation method includes the following steps:
(1) slurrying: smilax is weighed according to corresponding proportion and honeysuckle adds water filter after being crushed slurrying, is obtained primary spare Liquid
(2) it infusion and filters: weighing solubilizer after Radix Angelicae Sinensis, Radix Paeoniae Alba, Radix Astragali, Rhizoma Chuanxiong, rhizoma zingiberis and monkshood mixing according to corresponding proportion It impregnated, infusion and filtered, obtain secondary reserve liquid after cooling;
(3) stand: the secondary reserve liquid that the reserve liquid that step (1) is obtained is obtained with step (2) is mixed and stirred for It is stood after uniformly, obtains reserve liquid three times;
(4) finished product is made: finished product will be obtained after the filtering of reserve liquid three times in step (3).
5. according to claim 4 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, feature exists Amount of water and weighed medicinal material total quality ratio are 35-180:5-18 when, step (1) slurrying;
Preferably, amount of water and weighed medicinal material total quality ratio are 56-140:8-14 when the slurrying;
It is further preferred that amount of water and weighed medicinal material total quality ratio are 70-120:10-12 when the slurrying.
6. according to claim 4 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, feature exists In step (1) mixing time is 5-35 minutes;
Preferably, the mixing time is 10-30 minutes;
It is further preferred that the mixing time is 15-25 minutes.
7. according to claim 4 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, feature exists In the screen of selection 100-280 mesh after step (1) slurrying;
Preferably, the screen of 140-220 mesh is selected after the slurrying;
It is further preferred that selecting the screen of 180-200 mesh after the slurrying.
8. according to claim 4 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, feature exists In step (2) institute solubilizer includes water, and amount of water and weighed medicinal material total quality ratio are 180-500:18-50;
Preferably, the amount of water and weighed medicinal material total quality ratio are 220-450:22-46;
It is further preferred that the amount of water and weighed medicinal material total quality ratio are 280-350:28-35.
9. according to claim 4 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, feature exists In the infusion time is 30-75 minutes in the step (2);
Preferably, the infusion time is 45-60 minutes;
It is further preferred that the infusion time is 50 minutes.
10. according to claim 4 a kind of for treating the preparation method of the Chinese materia medica preparation of gynecology colpitis, feature exists In the temperature of secondary reserve liquid after cooling is 15-30 degrees Celsius in the step (2);
Preferably, the temperature of the secondary reserve liquid after cooling is 20-28 degrees Celsius;
It is further preferred that the temperature of the secondary reserve liquid after cooling is 23-25 degrees Celsius.
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