CN110179956A - 治疗多汗糜烂型脚气的中药外用洗剂 - Google Patents

治疗多汗糜烂型脚气的中药外用洗剂 Download PDF

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CN110179956A
CN110179956A CN201910385202.5A CN201910385202A CN110179956A CN 110179956 A CN110179956 A CN 110179956A CN 201910385202 A CN201910385202 A CN 201910385202A CN 110179956 A CN110179956 A CN 110179956A
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李艳
邵倩
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Hefei Hongkou Health Management Co ltd
Suzhou Yinghuang Pharmaceutical Co ltd
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Chongqing Medical and Pharmaceutical College
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Abstract

本发明公开了一种治疗多汗糜烂型脚气的中药外用洗剂，其特征在于：由重量份数的以下组分组成：中药药液100‑250份、桉叶油10‑20份、10％‑15％冰醋酸80‑100份、明矾1‑5份；其中所述中药药液由重量份数的以下中草药加水熬制而得：当归3‑5份、生地黄4‑6份、牛蒡子5‑8份、红花3‑5份、木通3‑5份、赤芍3‑5份、牡丹皮4‑6份、连翘4‑6份、艾叶3‑5份、老姜5‑8份、苦参3‑5份、黄连4‑6份。通过临床运用表明在中医辩证为多汗糜烂型脚气的基础上用本方，可以得到有效治疗，治愈率达到95％以上。本发明的中草药易得，疗效好，价格便宜、针对性强。

Description

治疗多汗糜烂型脚气的中药外用洗剂
技术领域
本发明涉及一种治疗多汗糜烂型脚气的中药外用洗剂，属于中药领域。
背景技术
足癣(俗名“香港脚”、脚气)，系真菌感染引起，其皮肤损害往往是先单侧(即单脚)发生，数周或数月后才感染到对侧。足癣的皮肤损害有一特点，即边界清楚，可逐渐向外扩展。因病情发展或搔抓，可出现糜烂、渗液，甚或细菌感染，出现脓疱等。
足癣是由致病性真菌引起的足部皮肤病，具有传染性。足癣在全世界广为流行，在热带和亚热带地区更为普遍。在我国，足癣的发病率也相当高。人的足底和趾间没有皮脂腺，从而缺乏抑制皮肤丝状真菌的脂肪酸，生理防御机能较差，而这些部位的皮肤汗腺却很丰富，出汗比较多，加之空气流通性差、局部潮湿温暖，有利于丝状真菌的生长。此外，足底部位皮肤角质层较厚，角质层中的角蛋白是真菌的丰富营养物质，有利于真菌的生长。
妇女在妊娠期间，由于内分泌的变化，引起皮肤抵抗真菌感染的能力下降，易患足癣。肥胖者因趾间潮湿，汗液浸渍易患足癣。足部皮肤受外伤，破坏了皮肤的防御功能，也是诱发足癣的因素之一。糖尿病患者由于缺乏胰岛素导致物质代谢紊乱，皮肤含糖量增加导致抵抗力下降，也易患足癣。滥用抗生素，长期使用皮质类固醇激素和免疫抑制剂等，使皮肤正常菌群失调，也会增加足癣的易感性。
足癣临床表现有以下几种类型：
1.水疱型
多发生在夏季，表现为趾间、足缘、足底出现米粒大小，深在性水疱，疏散或成群分布，疱壁较厚，内容清澈，不易破裂，相互融合形成多房性水疱，撕去疱壁，可见蜂窝状基底及鲜红色糜烂面，剧烈瘙痒。
2.糜烂型
表现为局部表皮角质层浸软发白。由于走动时不断摩擦表皮脱落，露出鲜红色糜烂面；严重者趾缝间、趾腹与足底交界处皮肤均可累及，瘙痒剧烈，多发于第3、4、5趾缝间。常见于多汗者。
3.鳞屑角化型
症状是足跖、足缘、足跟部皮肤脚趾增厚、粗糙、脱屑，鳞屑成片状或小点状，反复脱落。
足癣用药最关键的是应按照分型进行连贯正规的治疗。切勿自行盲目治疗，常常使病情延误和加重。针对不同类型的脚气使用何种合适的药物进行治疗成为我们需要解决的技术问题。
发明内容
针对上述技术问题，本发明的目的在于提供一种治疗多汗糜烂型脚气的中药外用洗剂。
为了实现上述目的，本发明的技术方案为：一种治疗多汗糜烂型脚气的中药外用洗剂，其特征在于：由重量份数的以下组分组成：中药药液100-250份、桉叶油10-20份、10％-15％冰醋酸80-100份、明矾1-5份；
其中所述中药药液由重量份数的以下中草药加水熬制而得：当归3-5份、生地黄4-6份、牛蒡子5-8份、红花3-5份、木通3-5份、赤芍3-5份、牡丹皮4-6份、连翘4-6份、艾叶3-5份、老姜5-8份、苦参3-5份、黄连4-6份。
优选：由重量份数的以下组分组成：中药药液150-200份、桉叶油15-20份、10％-15％冰醋酸100份、明矾2-4份。
优选：所述老姜为带皮老姜。带皮老姜性凉。
上述方案中：中药药液的熬制过程为：将当归、生地黄、牛蒡子、红花、木通、赤芍、牡丹皮、连翘、艾叶、老姜、苦参、黄连加入熬制容器中，加水淹没，大火烧开，小火熬制1-2h，倒出药液，继续加水淹没熬制1-2h，倒出药液，如此反复熬制2-3次，合并药液得到中药药液。
经过中医辨证分析，出汗糜烂型脚气是由于身体的小汗腺分泌旺盛，汗腺分泌物在细菌、霉菌分解下产生脚气。出汗促使细菌容易繁殖，因此脚爱出汗的人多数患有脚气。治疗出汗型脚气，需采用凉血与杀菌同时进行，方可取得最终的治疗效果。
本发明遵循中医原理，各组方中：
桉叶油：主要富含1,8-桉叶素等，具有消炎杀菌作用，对化脓性细菌、金黄色葡萄糖球菌具有较强的抑制作用，对绿脓杆菌、大肠杆菌等也有较好的抑制效果。
明矾：解毒杀虫,燥湿止痒，收敛干燥，减少出汗，保持足部干燥。
冰醋酸：抗真菌、去角质、去死皮。
苦参：抗菌消炎，对金黄色葡萄球菌有很强的抑菌作用，而苦参水浸剂则对堇色毛癣菌、同心性毛癣菌、许兰毛癣菌、奥杜盎小芽孢癣菌等有抑制作用。清热燥湿，还可以平衡人体皮肤油脂的分泌，有疏通收敛毛孔的功效。
生姜：抗炎杀菌，辅以祛湿。
艾叶：杀菌止痒，辅以祛湿。
当归：补血、活血。
牛蒡子：疏散风热；清热解毒透疹。
红花：活血、消炎。
木通：活血通脉、清热。
生地黄：为清热凉血药。
赤芍：凉血，活血祛瘀。
牡丹皮：清热凉血、活血化淤、退虚热。
连翘：煎剂在体外有抗菌作用，可抑制伤寒杆菌、副伤寒杆菌、大肠杆菌、痢疾杆菌、白喉杆菌及霍乱弧菌、葡萄球菌、链球菌等。连翘对沙门氏菌属，对痢疾杆菌、金黄色葡萄球菌之抑制较好。与黄连组方，体外抑菌作用比单用连翘更强。
通过临床运用表明：在中医辩证为多汗糜烂型脚气的基础上用本方，脚气可以得到有效治疗，本发明已经针对57例多汗糜烂型脚气进行治疗，治愈率达到95％以上。本发明的中草药易得，疗效好，价格便宜、针对性强。
具体实施方式
下面通过实施例，对本发明作进一步说明：
实施例1
刘某某，男，32岁，患脚气多年，脚易出汗，趾缝间、趾腹与足底表皮角质层浸软发白，表皮脱落，出现鲜红色糜烂面，瘙痒剧烈。
准备当归3g、生地黄4g、牛蒡子5g、红花3g、木通4g份、赤芍5g份、牡丹皮4g、连翘5g、艾叶4g、带皮老姜5g、苦参3g、黄连4g。将当归、生地黄、牛蒡子、红花、木通、赤芍、牡丹皮、连翘、艾叶、带皮老姜、苦参、黄连加入熬制容器中，加水淹没，大火烧开，小火熬制1h，倒出药液，继续加水淹没熬制1h，倒出药液，如此反复熬制3次，合并药液得到中药药液。
取中药药液100份、桉叶油10份、质量浓度为10％的冰醋酸100份、明矾1份混合均匀，溶液的量以能将双脚淹没为宜，浸泡脚。每晚一次，一次半小时以上，连续泡15天，脚气治愈。
实施例2
李某某，男，58岁，患脚气多年，脚易出汗，趾缝间、趾腹与足底表皮角质层浸软发白，表皮脱落，鲜红色糜烂面，瘙痒剧烈。
准备当归5g、生地黄6g、牛蒡子8g、红花5g、木通5g、赤芍3g、牡丹皮6g、连翘6g、艾叶5g、带皮老姜8g、苦参5g、黄连6g。将当归、生地黄、牛蒡子、红花、木通、赤芍、牡丹皮、连翘、艾叶、带皮老姜、苦参、黄连加入熬制容器中，加水淹没，大火烧开，小火熬制2h，倒出药液，继续加水淹没熬制2h，倒出药液，如此反复熬制2次，合并药液得到中药药液。
取中药药液200份、桉叶油15份、质量浓度15％冰醋酸80份、明矾5份混合，溶液的量以能将双脚淹没为宜，浸泡脚。每晚一次，一次半小时以上，连续泡15天，脚气治愈。
实施例3
钱某，男，29岁，患脚气多年，脚易出汗，趾缝间、趾腹与足底表皮角质层浸软发白，表皮脱落，鲜红色糜烂面，瘙痒剧烈。
准备当归4g、生地黄5g、牛蒡子7g、红花5g、木通4g、赤芍4g、牡丹皮4g、连翘4g、艾叶3g、带皮老姜6g、苦参4g、黄连4g。将当归、生地黄、牛蒡子、红花、木通、赤芍、牡丹皮、连翘、艾叶、带皮老姜、苦参、黄连加入熬制容器中，加水淹没，大火烧开，小火熬制1-2h，倒出药液，继续加水淹没熬制1-2h，倒出药液，如此反复熬制2-3次，合并药液得到中药药液。
取中药药液150份、桉叶油18份、12％冰醋酸100份、明矾2份混合，溶液的量以能将双脚淹没为宜，浸泡脚。每晚一次，一次半小时以上，连续泡18天，脚气治愈。
实施例4
李某，女，30岁，外出住旅社感染脚气，脚易出汗，趾缝间、趾腹与足底表皮角质层浸软发白，表皮脱落，鲜红色糜烂面，瘙痒剧烈。
准备当归3g、生地黄5g、牛蒡子7g、红花4g、木通3g、赤芍3g、牡丹皮6g、连翘4g、艾叶5g、带皮老姜7g、苦参3g、黄连6g。将当归、生地黄、牛蒡子、红花、木通、赤芍、牡丹皮、连翘、艾叶、带皮老姜、苦参、黄连加入熬制容器中，加水淹没，大火烧开，小火熬制2h，倒出药液，继续加水淹没熬制2h，倒出药液，如此反复熬制3次，合并药液得到中药药液。
取中药药液250份、桉叶油20份、15％冰醋酸100份、明矾4份混合，溶液的量以能将双脚淹没为宜，浸泡脚。每晚一次，一次半小时以上，连续泡12天，脚气治愈。
本发明不局限于上述实施例，本领域的普通技术人员可以理解：在不脱离本发明的原理和宗旨的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由权利要求及其等同物限定。

Claims (4)

1.一种治疗多汗糜烂型脚气的中药外用洗剂，其特征在于：由重量份数的以下组分组成：中药药液100-250份、桉叶油10-20份、10％-15％冰醋酸80-100份、明矾1-5份；
其中所述中药药液由重量份数的以下中草药加水熬制而得：当归3-5份、生地黄4-6份、牛蒡子5-8份、红花3-5份、木通3-5份、赤芍3-5份、牡丹皮4-6份、连翘4-6份、艾叶3-5份、老姜5-8份、苦参3-5份、黄连4-6份。
2.一种治疗多汗糜烂型脚气的中药外用洗剂，其特征在于：由重量份数的以下组分组成：中药药液150-200份、桉叶油15-20份、10％-15％冰醋酸100份、明矾2-4份。
3.根据权利要求1所述治疗多汗糜烂型脚气的中药外用洗剂，其特征在于：所述老姜为带皮老姜。
4.根据权利要求1或2或3所述治疗多汗糜烂型脚气的中药外用洗剂，其特征在于，中药药液的熬制过程为：将当归、生地黄、牛蒡子、红花、木通、赤芍、牡丹皮、连翘、艾叶、老姜、苦参、黄连加入熬制容器中，加水淹没，大火烧开，小火熬制1-2h，倒出药液，继续加水淹没熬制1-2h，倒出药液，如此反复熬制2-3次，合并药液得到中药药液。
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