CN1101556A

CN1101556A - Embolism clearing powder and its preparation method

Info

Publication number: CN1101556A
Application number: CN 93115841
Authority: CN
Inventors: 周耀群
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-10-09
Filing date: 1993-10-09
Publication date: 1995-04-19

Abstract

The present invention features that it is composed of root of membranous milk vetch, Liqusticum wallichii, Chinese angelica, peach kernel, root of herbaceous peony, safflower, earthworm, root of red-rooted salvia, pseudo-ginseng, fruit of citron, glutinous rehmannia, root of bidentate achyranthes, licorice root and borneol. The preparative method is dosing in accordance with the proportion, adding water to decoct the lotion, concentrating and adding alcohol to extrate the effective component, using sugar and starch as adjuncts to make into the medicine to be taken after being mixed with boiling water and taking with borneol capsule together. The efficacies are promoting blood circulation and removing blood stasis, regulating the flow of vital energy and removing obstruction to it, strengthening Yin, nourishing body fluid, ensuring proper downward flow of the blood and mild nature of drug. The curative effect for cerebral thrombosis comes up to 91%.

Description

Embolism clearing powder and its preparation method

The present invention relates to medicine, particularly a kind of Chinese medicine electuary for the treatment of the human body cerebral thrombosis disease and preparation method thereof.

Cerebral thrombosis, the traditional Chinese medical science is referred to as apoplexy, and its pathogenic factor traditional Chinese medical science is thought and is belonged to due to the blood stasis, so blood circulation promoting and blood stasis dispelling becomes the main rule of treatment of this disease of Chinese traditional treatment.

The Chinese patent medicine that is used for the treatment of at present cerebral thrombosis clinically is more, commercially available " embolism extinguishing oral liquid " (production of Jilin Province's Siping City pharmaceutical factory), make according to famous doctor family of China Qing Dynasty Wang Qingren " BUYANG HUANWU TANG ", this medicine contains the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Persicae, Radix Paeoniae Rubra, Flos Carthami, Pheretima.Though this medicine is better to the therapeutic effect of cerebral thrombosis, still have its weak point in the clinical use, the one, blood circulation invigorating efficacies is still strong inadequately; The 2nd, lack YIN nourishing and support the liquid composition, clothes of a specified duration easily cause gets angry; No QI regulating medicine, it is capable to be an impediment to gas; No conducting blood to flow downwards medicine is difficult for making the blood stasis that amasss in head descending; Lack hot waking up the patient from unconsciousness by clearing away heat key tunefulness medicine, make the drug action performance slow.

The objective of the invention is above-mentioned embolism extinguishing oral liquid is improved, overcome its shortcoming, provide a kind of blood circulation promoting and blood stasis dispelling function further to improve for clinical, and have regulating qi and dredging collateral, YIN nourishing concurrently and support that liquid, conducting blood to flow downwards, the property of medicine are gentle, drug effect is brought into play Chinese patent medicine granule faster, with the therapeutic effect of further raising to cerebral thrombosis.

Embolism clearing powder provided by the invention is to increase Chinese medicine ingredients such as Radix Salviae Miltiorrhizae, Radix Notoginseng, Fructus Aurantii, Radix Rehmanniae, Radix Achyranthis Bidentatae, Radix Glycyrrhizae and Borneolum Syntheticum on the prescription basis of BUYANG HUANWU TANG, and is that adjuvant is made with starch and multitudinous sugar.Wherein Radix Salviae Miltiorrhizae and Radix Notoginseng are further strengthened the blood circulation promoting and blood stasis dispelling function; Radix Rehmanniae plays YIN nourishing and supports the liquid effect; The Fructus Aurantii the chest stuffiness relieving is regulated the flow of vital energy, regulating functional activities of vital QI; Radix Achyranthis Bidentatae falls, but priming is descending, makes the head blood stasis descending; The Radix Glycyrrhizae mediation property of medicine; The hot waking up the patient from unconsciousness by clearing away heat key of Borneolum Syntheticum.After improving, make drug effect of the present invention comprehensive, curative effect further improves.Not only be used for treatment clinically, and can treat other thrombotic disease and treatment of conditions such as coronary heart disease, deficiency myocardial blood supply, angina pectoriss to cerebral thrombosis; Has tangible prevention of stroke effect simultaneously.

The preparation method of this embolism clearing powder is by Radix Astragali 3500-4000 gram, Radix Angelicae Sinensis 800-1200 gram, Radix Rehmanniae 800-1200 gram, Semen Persicae 450-550 gram, Radix Paeoniae Rubra 450-500 gram, Rhizoma Chuanxiong 480-550 gram, Pheretima 450-550 gram, Fructus Aurantii 480-530 gram, Radix Notoginseng 480-530 gram, Radix Salviae Miltiorrhizae 500-1000 gram, Radix Glycyrrhizae 220-280 gram, Radix Achyranthis Bidentatae 600-900 restrains batching, the clear water that adds 10 times of weight is heated to 100 ℃, 2 hours, leaches medicinal liquid, add Flos Carthami 600-900 gram again, add the clear water of 8 times of weight of former medicine again, post bake to 100 ℃, 1 hour, leach medicinal liquid, twice medicinal liquid merges, and is concentrated to proportion when being 1.2(40 ℃), add two times of weight concentrations and be 90% ethanol, mixing left standstill 12 hours, drew supernatant, when being concentrated into proportion and being 1.3(40 ℃), vacuum drying is pulverized, and adds multitudinous sugar and starch and ethanol pelletize, dry, sieving makes electuary, 14-18 is restrained Borneolum Syntheticum make capsule, with the electuary adapted.

Embodiment:

Press the Radix Astragali 3750 grams, Radix Angelicae Sinensis 1000 grams, Radix Rehmanniae 1000 grams, Semen Persicae 500 grams, Radix Paeoniae Rubra 500 grams, Rhizoma Chuanxiong 500 grams, Pheretima 500 grams, Fructus Aurantii 500 grams, Radix Notoginseng 500 grams, Radix Salviae Miltiorrhizae 750 grams, Radix Glycyrrhizae 250 grams, Radix Achyranthis Bidentatae 750 grams, batching, the water that adds 10 times of weight is heated to 100 ℃, 2 hours in extraction pot, leach medicinal liquid with flame filter press, add Flos Carthami 750 gram again, add the water post bake to 100 ℃ of 8 times of weight of former medicine, 1 hour, leach medicinal liquid with method, twice medicinal liquid merges, and records when being concentrated into proportion 1.2(40 ℃ by the concentrating under reduced pressure jar), add two times of weight concentrations and be 90% ethanol, stirring and evenly mixing left standstill 12 hours, drew supernatant, being concentrated into proportion 1.3(40 ℃ by the concentrating under reduced pressure pot records), by the vacuum drier drying, pulverizing adds multitudinous sugar and starch mixing, with 90% alcohol granulation, dry 12 mesh sieves of crossing, promptly get electuary, 600 bags of packing, every bag 10 gram.16 gram Borneolum Syntheticums are made 300 capsules, join two bagged soluble granules for every and take.

The above-mentioned electuary of clinical usefulness treatment cerebral thrombosis 76 examples, cerebral thrombosis acute phase 24 examples wherein, convalescent periods 31 example, sequela stage 21 examples, three times on the one, each two bags, serveing on half is a course of treatment, observation of curative effect after logotype three courses of treatment, total effective rate reaches 91%.Can find to take this medicine energy microcirculation improvement through every inspection, make Marjoram Extract, blood viscosity reduces, and flow velocity speeds, erythrocyte and platelet depolymerization, and microthrombus reduces and eliminates.This is the basic reason of this medicine to the higher curative effect of cerebral thrombosis.

Claims

1, a kind of embolism clearing powder contains Chinese medicine astragalus, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Persicae, Radix Paeoniae Rubra, Flos Carthami, Pheretima, it is characterized in that, also contains salviamiltiorrhizabung, Radix Notoginseng, Fructus Aurantii, Radix Rehmanniae, Radix Achyranthis Bidentatae, Radix Glycyrrhizae and Borneolum Syntheticum.

2, preparation method as the said embolism clearing powder of claim 1 is characterized in that, presses Radix Astragali 3500-4000 gram, Radix Angelicae Sinensis 800-1200 gram, Radix Rehmanniae 800-1200 gram, Semen Persicae 450-550 gram, Radix Paeoniae Rubra 450-500 gram, Rhizoma Chuanxiong 480-550 gram, Pheretima 450-550 gram, Fructus Aurantii 480-530 gram, Radix Notoginseng 480-530 gram, Radix Salviae Miltiorrhizae 500-1000 gram, Radix Glycyrrhizae 220-280 gram, Radix Achyranthis Bidentatae 600-900 restrains batching, and the clear water that adds 10 times of weight is heated to 100 ℃, 2 hours, leach medicinal liquid, add Flos Carthami 600-900 gram again, the clear water that adds 8 times of weight of former medicine again, post bake to 100 ℃ 1 hour, leaches medicinal liquid, twice medicinal liquid merges, being concentrated to proportion is 1.2(40 ℃), add the ethanol of two times of weight concentrations 90%, mixing, left standstill 12 hours, draw supernatant, being concentrated into proportion is 1.3(40 ℃), vacuum drying, pulverize, add multitudinous sugar and starch and ethanol pelletize, drying and screening makes electuary, with the capsule adapted that is made by 14-18 gram Borneolum Syntheticum.