CN110123943A - A kind of Chinese medicinal pill and preparation method thereof for treating type II diabetes - Google Patents

A kind of Chinese medicinal pill and preparation method thereof for treating type II diabetes Download PDF

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Publication number
CN110123943A
CN110123943A CN201910598850.9A CN201910598850A CN110123943A CN 110123943 A CN110123943 A CN 110123943A CN 201910598850 A CN201910598850 A CN 201910598850A CN 110123943 A CN110123943 A CN 110123943A
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parts
glue
tag
bryozoatum
radix rehmanniae
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王显容
彭一心
陈志休
绍素清
聂微芹
聂铃耘
王煜锦
刘思成
沈洁
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/586Turtles; Tortoises, e.g. terrapins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

The invention discloses a kind of Chinese medicinal pills for treating type II diabetes, including following components by weight: 20-28 parts of Radix Rehmanniae, 22-28 parts of Chinese yam, 16-23 parts of Schisandra chinensis, 22-28 parts of the tuber of dwarf lilyturf, 7-13 parts of pueraria lobata, 15-22 parts of clam meal, 7-12 parts of bryozoatum, 8-15 parts of sanchi flower, 10-18 parts of endothelium corneum gigeriae galli, 5-15 parts of donkey-hide gelatin, 8-13 parts of tortoise glue, 9-13 parts of deer horn glue, 12-17 parts of Resina Draconis and 8-14 parts of tag.The present invention uses the mutual compatibility of plurality of Chinese, thus the effect of playing good enriching yin, kidney tonifying, has effectively treated that kidney-yin deficiency sun is high, ensure that the good metabolism of kidney, to preferably be metabolized by kidney by blood glucose, play the role of blood glucose and let out blood glucose.

Description

A kind of Chinese medicinal pill and preparation method thereof for treating type II diabetes
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, and in particular to a kind of Chinese medicinal pill for treating type II diabetes and its system Preparation Method.
Background technique
The ability that insulin is generated in patients with NIDDM body not completely loses, and some patient's body insulin is even It generates excessively, but the function and effect of insulin are poor, therefore the insulin of patient's body is a kind of opposite shortage, can pass through certain A little oral drugs stimulate the secretion of internal insulin, mostly fall ill after 35-40 years old.
The Chinese and Western medicine for the treatment of type II diabetes is more at present, contributes to control blood glucose mostly and increases, can only treat the symptoms and Cannot and its it is basic, need it is long-term take, once deactivating, the state of an illness will rebound recurrence.
Summary of the invention
The technical problems to be solved by the invention are in view of the above shortcomings of the prior art, to provide a kind for the treatment of II type sugar The effect of Chinese medicinal pill of urine disease, which primarily serves enriching yin, kidney tonifying, by improving renal metabolism, make blood glucose more preferable Ground metabolism, to guarantee the normal of blood glucose.
The technical scheme adopted by the invention is that: a kind of Chinese medicinal pill for treating type II diabetes, including by weight Following components: 20-28 parts of Radix Rehmanniae, 22-28 parts of Chinese yam, 16-23 parts of Schisandra chinensis, 22-28 parts of the tuber of dwarf lilyturf, 7-13 parts of pueraria lobata, clam 15-22 parts of powder, 7-12 parts of bryozoatum, 8-15 parts of sanchi flower, 10-18 parts of endothelium corneum gigeriae galli, 5-15 parts of donkey-hide gelatin, 8-13 parts of tortoise glue, deer horn glue 9-13 parts, 12-17 parts of Resina Draconis and 8-14 parts of tag.
Preferably, the Chinese medicinal pill of the treatment type II diabetes includes 25 parts of Radix Rehmanniae by weight, Chinese yam 25 Part, 20 parts of Schisandra chinensis, 25 parts of the tuber of dwarf lilyturf, 10 parts of pueraria lobata, 20 parts of clam meal, 10 parts of bryozoatum, 10 parts of sanchi flower, 15 parts of endothelium corneum gigeriae galli, 10 parts of donkey-hide gelatin, 10 parts of tortoise glue, 10 parts of deer horn glue, 15 parts of Resina Draconis and 10 parts of tag.
Preferably, the Chinese medicinal pill of the treatment type II diabetes includes 20 parts of Radix Rehmanniae by weight, Chinese yam 26 Part, 18 parts of Schisandra chinensis, 22 parts of the tuber of dwarf lilyturf, 9 parts of pueraria lobata, 18 parts of clam meal, 12 parts of bryozoatum, 12 parts of sanchi flower, 18 parts of endothelium corneum gigeriae galli, Ah 8 parts of glue, 10 parts of tortoise glue, 11 parts of deer horn glue, 15 parts of Resina Draconis and 12 parts of tag.
Preferably, the Chinese medicinal pill of the treatment type II diabetes includes 26 parts of Radix Rehmanniae by weight, Chinese yam 22 Part, 17 parts of Schisandra chinensis, 26 parts of the tuber of dwarf lilyturf, 13 parts of pueraria lobata, 20 parts of clam meal, 9 parts of bryozoatum, 8 parts of sanchi flower, 15 parts of endothelium corneum gigeriae galli, Ah 15 parts of glue, 13 parts of tortoise glue, 13 parts of deer horn glue, 17 parts of Resina Draconis and 14 parts of tag.
Preferably, the Chinese medicinal pill of the treatment type II diabetes includes 28 parts of Radix Rehmanniae by weight, Chinese yam 24 Part, 23 parts of Schisandra chinensis, 27 parts of the tuber of dwarf lilyturf, 8 parts of pueraria lobata, 22 parts of clam meal, 8 parts of bryozoatum, 14 parts of sanchi flower, 12 parts of endothelium corneum gigeriae galli, Ah 11 parts of glue, 11 parts of tortoise glue, 11 parts of deer horn glue, 14 parts of Resina Draconis and 9 parts of tag.
A kind of preparation method of Chinese medicinal pill that treating type II diabetes, comprising the following steps:
(1) according to the ratio choose Radix Rehmanniae, Chinese yam, Schisandra chinensis, the tuber of dwarf lilyturf, pueraria lobata, clam meal, bryozoatum, sanchi flower, endothelium corneum gigeriae galli, Donkey-hide gelatin, tortoise glue, deer horn glue, Resina Draconis and tag;
(2) spare after brewed using 90-110 DEG C of boiling water brewed Radix Rehmanniae 15-25min;
(3) high fire boiling tag 25-35min is used, it is spare after boiling;
(4) by the Chinese yam of selection, Schisandra chinensis, the tuber of dwarf lilyturf, pueraria lobata, clam meal, bryozoatum, sanchi flower, endothelium corneum gigeriae galli, donkey-hide gelatin, tortoise Glue, deer horn glue, Resina Draconis and it is brewed after Radix Rehmanniae and tag after boiling ancient cooking vessel furnaces are all added, while be added do not cross the water of medicinal material into Row tanning, the control of tanning temperature are 80h in 500-600 DEG C, tanning time, and tanning is later by the tool molding of ball pattern to get controlling Treat the Chinese medicinal pill of type II diabetes.
Radix rehmanniae recen: clearing heat and cooling blood, yin-nourishing are promoted the production of body fluid.For the deep red polydipsia of pyreticosis tongue, yin asthenia generating intrinsic heat, hectic fever due to yin labor is hot, and interior heat disappears Yearningly;
Chinese yam: invigorating the spleen, tonifying lung are reinforced the kidney, strengthening the essence.For tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission, abnormal heat are quenched one's thirst;
Schisandra chinensis: astringency inducing, supplementing qi and promoting the production of body fluid, tonifying kidney and calming nerves.For long-last cough and virtual asthma, emission, enuresis frequent micturition, saliva wound It is thirsty, Heat Diabetes;
Radix Ophiopogonis door: Yin nourishing and lung moistening, relieving restlessness and restlessness, reinforcing stomach reg fluid.For the deficiency of the heart-yin or lung-stomach yin deficiency;
Pueraria lobata: expelling pathogenic factors from muscles and skin is brought down a fever, and promoting eruption promotes the production of body fluid to quench thirst, Shengyang Zhixie.For promoting the production of body fluid to quench thirst, pyreticosis it is thirsty, the deficiency of Yin is quenched one's thirst, Heat is purged heat dysentery, splenasthenic diarrhea;
Bryozoatum: clearing lung-heat fire changes old phlegm, softening hard masses are treating stranguria.It controls phlegm heat panting to cough, old phlegm block, goiter, scrofula, stranguria syndrome, hernia Gas, sore swells, mesh screen.For quenching the thirst, controls leaching, helps digestion, disappear hot phlegm;
Sanchi flower: there is the effect of heat-clearing, calming the liver, decompression.For clearing heat and detoxicating, calming the liver cool blood, hypertension and hyperlipemia, promote the production of body fluid only Yearningly, refresh oneself tonifying Qi, and myocardial oxygen delivery ability can be improved, enhance body's immunity;
Endothelium corneum gigeriae galli: stomach strengthening and digestion promoting, arresting seminal emission, treating stranguria fossil.For dyspepsia, vomiting dysentery, infantile malnutrition is lost Urine, spermatorrhea, the puckery pain of urolithiasis, distension of gallbladder, hypochondriac pain;
Donkey-hide gelatin: nourishing yin and supplementing blood controls the deficiency of blood, cough due to consumptive disease.For the extremely voluminous symptoms like malaria of labor, waist abdominal pain, foot acid cannot be stood long, Nourishing the liver gas, strongly stretches muscle, adds essence and reinforces the kidney;
Tortoise glue: enriching yin is enriched blood, hemostasis.For deficiency of Yin anemia, the hot hectic fever due to yin of labor, haematemesis, bleeding from five sense organs or subcutaneous tissue, dysphoria with smothery sensation palpitation with fear, kidney deficiency waist Bitterly, flaccidity of feet and knees;
Deer horn glue: yang-tonifying, nourishing yin and supplementing blood.For tonifying Qi, puckery empty essence, strengthening the muscles and bones, weak chronic cough, void breathe it is short, simultaneously also With tonify the blood and arrest bleeding, a variety of nutrition health-care functions such as tonifying kidney and strengthening yang;
Resina Draconis: there is the effect of promoting blood circulation to remove blood stasis, the blood of analgesic therapy, expelling pus and promoting granulation.For traumatic injury, hemostasis is had a pain, woman Effeminate blood stagnation, traumatic hemorrhage, running sore do not close up long and chronic colitis caused by the diseases such as abdominal pain, diarrhea;
Tag: tonifying spleen and kidney, eliminating cold to stop pain, the big heat of great Xin, Wen Yang is by cold effect.For the insufficiency of the kidney yang, aversion to cold and cold limbs, Hypoactivity of spleen-YANG;
Clam meal: energy heat-clearing, dampness removing, resolving sputum, softening hard masses.It makes the fishy smell that can remove drug altogether with drug, heightens the effect of a treatment.It is main to use In ironed donkey-hide gelatin.
Resina Draconis-promoting blood circulation to remove blood stasis;Tag processed-eliminating cold to stop pain Wen Yang is by cold clearing and activating the channels and collaterals;Donkey-hide gelatin, tortoise glue and deer horn glue are given and are mended Qi and blood nourishing and strengthening Yin and Yang;Three's compatibility reaches warm spleen kidney cold dispelling and phlegm is gone to dehumidify, expelling pus and promoting granulation, while Yin-nourishing and Qi-supplementing blood, strengthening the bones and muscles, mends Kidney and enhancing body is to achieve the purpose that repairing kidney functions, so that the normal secretions for restoring insulin make function of human body that can voluntarily adjust sugar Metabolic function;
Endothelium corneum gigeriae galli, Chinese yam two build up one's health by taking tonic taste so that drug more preferably absorbs;Schisandra chinensis nourishing generate fluid, invigorate the kidney and stop nocturnal emission calming heart;Wheat Winter nourishing heart, lung, stomach-Yin deficiency;Pueraria lobata promotes the production of body fluid to quench thirst, Shengyang Zhixie;Bryozoatum clearing lung-heat fire, softening hard masses are treating stranguria;The decompression of sanchi flower calming the liver, Refresh oneself and tonifying Qi while improving myocardial oxygen delivery strengthen immunity.Adjuvant is balanced each other with main ingredient compatibility with reaching the vital organs of the human body, repairs pancreas Island element regeneration function plays the role of rushing down sugared blood sugar reducing function, fundamentally plays and effects a permanent cure.
The present invention uses the mutual compatibility of plurality of Chinese, so that the effect of playing good enriching yin, kidney tonifying, effectively treats Kidney-yin deficiency sun is high, ensure that the good metabolism of kidney, to be preferably metabolized by kidney by blood glucose, play blood glucose and Let out the effect of blood glucose.
Specific embodiment
Below in conjunction with specific embodiment, invention is further described in detail.
Embodiment 1
The preparation method of the Chinese medicinal pill for the treatment of type II diabetes provided in this embodiment, comprising the following steps:
(1) choose Radix Rehmanniae 25g, Chinese yam 25g, Schisandra chinensis 20g, tuber of dwarf lilyturf 25g, pueraria lobata 10g, clam meal 20g, bryozoatum 10g, Sanchi flower 10g, endothelium corneum gigeriae galli 15g, donkey-hide gelatin 10g, tortoise glue 10g, deer horn glue 10g, Resina Draconis 15g and tag 10g;
(2) part material pre-treatment;
Radix Rehmanniae: spare after brewed using the brewed Radix Rehmanniae 15-25min of 90-110 DEG C of boiling water;
Pueraria lobata: pueraria lobata polishing powdering is spare;
Bryozoatum: using spare after small fire cooking 20-30min;
Schisandra chinensis: using small fire frying 5-8min, spare after frying;
Resina Draconis: being dried using vigorous fire, spare after drying;
Donkey-hide gelatin: using spare after shao-hsing rice wine immersion 20-30min;
Deer horn glue: using spare after shao-hsing rice wine immersion 20-30min;
Tortoise glue: using spare after shao-hsing rice wine immersion 20-30min;
Tag: using high fire boiling 25-35min, spare after boiling
(3) by the Chinese yam of selection, the tuber of dwarf lilyturf, clam meal, sanchi flower, endothelium corneum gigeriae galli and the five tastes obtained after step (2) processing Ancient cooking vessel furnace is all added in son, bryozoatum, pueraria lobata, donkey-hide gelatin, tortoise glue, deer horn glue, Resina Draconis, Radix Rehmanniae and tag, while being added and not crossing medicinal material Water high fire using ancient method tanning, the control of tanning temperature is 80h in 500-600 DEG C, tanning time, and tanning is later by ball pattern Tool molding is to get the Chinese medicinal pill for treating type II diabetes.
Embodiment 2
The preparation method of the Chinese medicinal pill for the treatment of type II diabetes provided in this embodiment, comprising the following steps:
(1) choose Radix Rehmanniae 26g, Chinese yam 22g, Schisandra chinensis 17g, tuber of dwarf lilyturf 26g, pueraria lobata 13g, clam meal 20g, bryozoatum 9g, Sanchi flower 8g, endothelium corneum gigeriae galli 15g, donkey-hide gelatin 15g, tortoise glue 13g, deer horn glue 13g, Resina Draconis 17g and tag 14g;
(2) part material pre-treatment;
Radix Rehmanniae: spare after brewed using the brewed Radix Rehmanniae 15-25min of 90-110 DEG C of boiling water;
Pueraria lobata: pueraria lobata polishing powdering is spare;
Bryozoatum: using spare after small fire cooking 20-30min;
Schisandra chinensis: using small fire frying 5-8min, spare after frying;
Resina Draconis: being dried using vigorous fire, spare after drying;
Donkey-hide gelatin: using spare after shao-hsing rice wine immersion 20-30min;
Deer horn glue: using spare after shao-hsing rice wine immersion 20-30min;
Tortoise glue: using spare after shao-hsing rice wine immersion 20-30min;
Tag: using high fire boiling 25-35min, spare after boiling
(3) by the Chinese yam of selection, the tuber of dwarf lilyturf, clam meal, sanchi flower, endothelium corneum gigeriae galli and the five tastes obtained after step (2) processing Ancient cooking vessel furnace is all added in son, bryozoatum, pueraria lobata, donkey-hide gelatin, tortoise glue, deer horn glue, Resina Draconis, Radix Rehmanniae and tag, while being added and not crossing medicinal material Water high fire using ancient method tanning, the control of tanning temperature is 80h in 500-600 DEG C, tanning time, and tanning is later by ball pattern Tool molding is to get the Chinese medicinal pill for treating type II diabetes.
Embodiment 3
The preparation method of the Chinese medicinal pill for the treatment of type II diabetes provided in this embodiment, comprising the following steps:
(1) choose Radix Rehmanniae 20g, Chinese yam 26g, Schisandra chinensis 18g, tuber of dwarf lilyturf 22g, pueraria lobata 9g, clam meal 18g, bryozoatum 12g, Sanchi flower 12g, endothelium corneum gigeriae galli 18g, donkey-hide gelatin 8g, tortoise glue 10g, deer horn glue 11g, Resina Draconis 15g and tag 12g;
(2) part material pre-treatment;
Radix Rehmanniae: spare after brewed using the brewed Radix Rehmanniae 15-25min of 90-110 DEG C of boiling water;
Pueraria lobata: pueraria lobata polishing powdering is spare;
Bryozoatum: using spare after small fire cooking 20-30min;
Schisandra chinensis: using small fire frying 5-8min, spare after frying;
Resina Draconis: being dried using vigorous fire, spare after drying;
Donkey-hide gelatin: using spare after shao-hsing rice wine immersion 20-30min;
Deer horn glue: using spare after shao-hsing rice wine immersion 20-30min;
Tortoise glue: using spare after shao-hsing rice wine immersion 20-30min;
Tag: using high fire boiling 25-35min, spare after boiling
(3) by the Chinese yam of selection, the tuber of dwarf lilyturf, clam meal, sanchi flower, endothelium corneum gigeriae galli and the five tastes obtained after step (2) processing Ancient cooking vessel furnace is all added in son, bryozoatum, pueraria lobata, donkey-hide gelatin, tortoise glue, deer horn glue, Resina Draconis, Radix Rehmanniae and tag, while being added and not crossing medicinal material Water high fire using ancient method tanning, the control of tanning temperature is 80h in 500-600 DEG C, tanning time, and tanning is later by ball pattern Tool molding is to get the Chinese medicinal pill for treating type II diabetes.
Embodiment 4
The preparation method of the Chinese medicinal pill for the treatment of type II diabetes provided in this embodiment, comprising the following steps:
(1) Radix Rehmanniae 28g, Chinese yam 24g, Schisandra chinensis 23g, tuber of dwarf lilyturf 27g, pueraria lobata 8g, clam meal 22g, bryozoatum 8g, three are chosen Seven flower 14g, endothelium corneum gigeriae galli 12g, donkey-hide gelatin 11g, tortoise glue 11g, deer horn glue 11g, Resina Draconis 14g and tag 9g;
(2) part material pre-treatment;
Radix Rehmanniae: spare after brewed using the brewed Radix Rehmanniae 15-25min of 90-110 DEG C of boiling water;
Pueraria lobata: pueraria lobata polishing powdering is spare;
Bryozoatum: using spare after small fire cooking 20-30min;
Schisandra chinensis: using small fire frying 5-8min, spare after frying;
Resina Draconis: being dried using vigorous fire, spare after drying;
Donkey-hide gelatin: using spare after shao-hsing rice wine immersion 20-30min;
Deer horn glue: using spare after shao-hsing rice wine immersion 20-30min;
Tortoise glue: using spare after shao-hsing rice wine immersion 20-30min;
Tag: using high fire boiling 25-35min, spare after boiling
(3) by the Chinese yam of selection, the tuber of dwarf lilyturf, clam meal, sanchi flower, endothelium corneum gigeriae galli and the five tastes obtained after step (2) processing Ancient cooking vessel furnace is all added in son, bryozoatum, pueraria lobata, donkey-hide gelatin, tortoise glue, deer horn glue, Resina Draconis, Radix Rehmanniae and tag, while being added and not crossing medicinal material Water high fire using ancient method tanning, the control of tanning temperature is 80h in 500-600 DEG C, tanning time, and tanning is later by ball pattern Tool molding is to get the Chinese medicinal pill for treating type II diabetes.
Clinical test:
(1) clinical data:
The Patients with NIDDM for randomly selecting more than 200 examples carries out clinical observation, and male 98, female 112, the age is in 40- Between 60 years old.
(2) diagnostic criteria:
Mainly judged according to the morning fasting blood-glucose of measurement patient and 2h-plasma glucose.
(3) treatment method:
It is treated using comparison, patient is divided into two groups, two groups of male to female ratios, age and the course of disease are average;Every group 105, one Group is experimental group, and one group is control group;
Control group: daily normal doctor trained in Western medicine dietary therapy;
Experimental group: taking Chinese medicinal pill of the present invention daily before the meal, 3-5 each;
(4) observation of curative effect:
Two groups for the treatment of times are identical, are six months, and observation of curative effect detects morning fasting blood-glucose and 2h-plasma glucose;
The morning fasting blood-glucose of first month, control group and experimental group is not much different, in 12.3 ± 1.78mmol/L;It is right It is 16.4 ± 2.28mmol/L according to group 2h-plasma glucose, experimental group 2h-plasma glucose is 15.89 ± 2.12mmol/L, experimental group meal 2h blood glucose is slightly below control group afterwards;
Second month, the morning fasting blood-glucose of control group are 12.11 ± 1.52mmol/L, the morning fasting blood-glucose of experimental group Morning fasting blood-glucose for 11.92 ± 1.47mmol/L, experimental group is slightly below control group;Control group 2h-plasma glucose is 15.64 ± 1.98mmol/L, experimental group 2h-plasma glucose are 14.75 ± 1.84mmol/L, and experimental group 2h-plasma glucose is lower than control group;
Third month, the morning fasting blood-glucose of control group are 11.78 ± 1.66mmol/L, the morning fasting blood-glucose of experimental group Morning fasting blood-glucose for 11.27 ± 1.32mmol/L, experimental group is lower than control group;Control group 2h-plasma glucose be 14.58 ± 1.76mmol/L, experimental group 2h-plasma glucose are 13.46 ± 1.68mmol/L, and experimental group 2h-plasma glucose is lower than control group;
Four month, the morning fasting blood-glucose of control group was 11.32 ± 1.48mmol/L, the morning fasting blood-glucose of experimental group Morning fasting blood-glucose for 10.18 ± 1.76mmol/L, experimental group is lower than control group;Control group 2h-plasma glucose be 13.22 ± 1.43mmol/L, experimental group 2h-plasma glucose are 11.88 ± 1.52mmol/L, and experimental group 2h-plasma glucose is significantly lower than control Group;
Five month, the morning fasting blood-glucose of control group was 10.91 ± 1.52mmol/L, the morning fasting blood-glucose of experimental group Morning fasting blood-glucose for 8.89 ± 1.44mmol/L, experimental group is significantly lower than control group;Control group 2h-plasma glucose is 12.06 ± 1.26mmol/L, experimental group 2h-plasma glucose are 10.34 ± 1.43mmol/L, and experimental group 2h-plasma glucose is significantly lower than control Group;
Six month, the morning fasting blood-glucose of control group was 10.36 ± 1.13mmol/L, the morning fasting blood-glucose of experimental group Morning fasting blood-glucose for 7.48 ± 0.98mmol/L, experimental group is significantly lower than control group;Control group 2h-plasma glucose is 10.97 ± 1.16mmol/L, experimental group 2h-plasma glucose are 8.23 ± 1.21mmol/L, and experimental group 2h-plasma glucose is significantly lower than control Group.
Complex clinical observation is as a result, it can be concluded that Chinese medicinal pill according to the present invention has good drop Sugar effect, either fasting blood-glucose or postprandial blood sugar, improve significantly.
The above is only the preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, any The transformation and replacement carried out based on technical solution provided by the present invention and inventive concept should all be covered in protection model of the invention In enclosing.

Claims (6)

1. a kind of Chinese medicinal pill for treating type II diabetes, it is characterised in that: including following components by weight: Radix Rehmanniae 20-28 parts, 22-28 parts of Chinese yam, 16-23 parts of Schisandra chinensis, 22-28 parts of the tuber of dwarf lilyturf, 7-13 parts of pueraria lobata, 15-22 parts of clam meal, bryozoatum 7-12 parts, 8-15 parts of sanchi flower, 10-18 parts of endothelium corneum gigeriae galli, 5-15 parts of donkey-hide gelatin, 8-13 parts of tortoise glue, 9-13 parts of deer horn glue, Resina Draconis 12- 17 parts and tag 8-14 parts.
2. a kind of Chinese medicinal pill for treating type II diabetes according to claim 1, it is characterised in that: including by weight 25 parts of the Radix Rehmanniae of meter, 25 parts of Chinese yam, 20 parts of Schisandra chinensis, 25 parts of the tuber of dwarf lilyturf, 10 parts of pueraria lobata, 20 parts of clam meal, 10 parts of bryozoatum, Radix Notoginseng Spend 10 parts, 15 parts of endothelium corneum gigeriae galli, 10 parts of donkey-hide gelatin, 10 parts of tortoise glue, 10 parts of deer horn glue, 15 parts of Resina Draconis and 10 parts of tag.
3. a kind of Chinese medicinal pill for treating type II diabetes according to claim 1, it is characterised in that: including by weight 20 parts of the Radix Rehmanniae of meter, 26 parts of Chinese yam, 18 parts of Schisandra chinensis, 22 parts of the tuber of dwarf lilyturf, 9 parts of pueraria lobata, 18 parts of clam meal, 12 parts of bryozoatum, Radix Notoginseng Spend 12 parts, 18 parts of endothelium corneum gigeriae galli, 8 parts of donkey-hide gelatin, 10 parts of tortoise glue, 11 parts of deer horn glue, 15 parts of Resina Draconis and 12 parts of tag.
4. a kind of Chinese medicinal pill for treating type II diabetes according to claim 1, it is characterised in that: including by weight 26 parts of the Radix Rehmanniae of meter, 22 parts of Chinese yam, 17 parts of Schisandra chinensis, 26 parts of the tuber of dwarf lilyturf, 13 parts of pueraria lobata, 20 parts of clam meal, 9 parts of bryozoatum, Radix Notoginseng Spend 8 parts, 15 parts of endothelium corneum gigeriae galli, 15 parts of donkey-hide gelatin, 13 parts of tortoise glue, 13 parts of deer horn glue, 17 parts of Resina Draconis and 14 parts of tag.
5. a kind of Chinese medicinal pill for treating type II diabetes according to claim 1, it is characterised in that: including by weight 28 parts of the Radix Rehmanniae of meter, 24 parts of Chinese yam, 23 parts of Schisandra chinensis, 27 parts of the tuber of dwarf lilyturf, 8 parts of pueraria lobata, 22 parts of clam meal, 8 parts of bryozoatum, sanchi flower 14 parts, 12 parts of endothelium corneum gigeriae galli, 11 parts of donkey-hide gelatin, 11 parts of tortoise glue, 11 parts of deer horn glue, 14 parts of Resina Draconis and 9 parts of tag.
6. the preparation method of -5 any a kind of Chinese medicinal pills for treating type II diabetes according to claim 1, feature It is: the following steps are included:
(1) according to the ratio choose Radix Rehmanniae, Chinese yam, Schisandra chinensis, the tuber of dwarf lilyturf, pueraria lobata, clam meal, bryozoatum, sanchi flower, endothelium corneum gigeriae galli, donkey-hide gelatin, Tortoise glue, deer horn glue, Resina Draconis and tag;
(2) spare after brewed using 90-110 DEG C of boiling water brewed Radix Rehmanniae 15-25min;
(3) high fire boiling tag 25-35min is used, it is spare after boiling;
(4) by the Chinese yam of selection, Schisandra chinensis, the tuber of dwarf lilyturf, pueraria lobata, clam meal, bryozoatum, sanchi flower, endothelium corneum gigeriae galli, donkey-hide gelatin, tortoise glue, deer Glue, Resina Draconis and it is brewed after Radix Rehmanniae and tag after boiling ancient cooking vessel furnaces are all added, while being added and not crossing the water of medicinal material and endured System, the control of tanning temperature are 80h in 500-600 DEG C, tanning time, and tanning is later by the tool molding of ball pattern to get treatment II The Chinese medicinal pill of patients with type Ⅰ DM.
CN201910598850.9A 2019-07-03 2019-07-03 A kind of Chinese medicinal pill and preparation method thereof for treating type II diabetes Pending CN110123943A (en)

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Publication number Priority date Publication date Assignee Title
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CN107334930A (en) * 2017-07-03 2017-11-10 德兴市宋氏葛业有限公司 A kind of kudzuvine root starch Chinese medicine preparation and its processing technology for preventing and treating diabetes

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397459A (en) * 2011-10-19 2012-04-04 李顺光 Traditional Chinese medicine for treating diabetes and preparation method thereof
CN103816428A (en) * 2014-03-26 2014-05-28 李常明 Preparation for effectively treating diabetes mellitus
CN106728835A (en) * 2016-12-27 2017-05-31 河南亚都实业有限公司 A kind of Chinese medicine for treating diabetes
CN107334930A (en) * 2017-07-03 2017-11-10 德兴市宋氏葛业有限公司 A kind of kudzuvine root starch Chinese medicine preparation and its processing technology for preventing and treating diabetes

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