CN110123650B - Dressing with antibacterial and moisturizing functions and preparation method thereof - Google Patents
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- CN110123650B CN110123650B CN201910347702.XA CN201910347702A CN110123650B CN 110123650 B CN110123650 B CN 110123650B CN 201910347702 A CN201910347702 A CN 201910347702A CN 110123650 B CN110123650 B CN 110123650B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention relates to a dressing with an antibacterial moisturizing function and a preparation method thereof, wherein the dressing with the antibacterial moisturizing function is prepared from the following raw materials: the dressing comprises a mixture B and a dressing body, wherein the mixture B comprises purified water, ozone, tea polyphenol, hyaluronic acid, oligopeptide-1 and antibacterial peptide, the dressing body is a fabric made of chemical short fibers, and the dressing with the antibacterial and moisturizing functions can be obtained by uniformly coating the mixture B on the dressing body. The dressing with the antibacterial and moisturizing functions can be applied to the skin surface of a human body to perform bacteriostasis, water supplementing and cleaning on the skin surface, can generate good bacteriostasis effects on staphylococcus, streptococcus, propionic acid bacteria and corynebacteria, has the functions of bacteriostasis and sterilization besides the water supplementing and moisturizing functions of the traditional skin care product, and has good antibacterial and moisturizing effects.
Description
Technical Field
The invention relates to the technical field of medical cosmetology, in particular to a dressing with antibacterial and moisturizing functions and a preparation method thereof.
Background
With the gradual development of the beauty industry, modern females pay more and more attention to skin care, and more people choose to use skin care products to achieve the purposes of skin care and beauty.
On one hand, the existing skin care products such as facial masks, water emulsion and the like have poor moisturizing and moisturizing functions and lack powerful and effective sterilization functions, or only pay attention to one aspect of functions. When the skin on the face or other parts is infected, bacteria on the skin need to be removed to reduce the risk of skin infection, and the traditional skin care products are slightly debilitated in this respect. On the other hand, in order to protect the product from microbial contamination and deterioration and prolong the shelf life of the product, a preservative is commonly added in the prior art to prevent the propagation of microorganisms, but the addition of the preservative can increase the irritation to the skin, so that the skin is sensitized by flushing and rash. The antibacterial peptide in animals can not only make the facial mask product have better skin antibacterial effect, but also prolong the preservation time and the efficacy of the product.
The plant extract has the effects of moisturizing and repairing congenital and is not easy to be allergic, and in order to improve the effect of the mask, a formula of combining the plant extract with a compound is adopted. However, the components are prone to interference with each other, which not only reduces efficacy but also causes other unexpected problems.
Therefore, a mask with antibacterial and moisturizing functions and a preparation method thereof are needed, which not only can effectively have the functions of moisturizing and antibacterial restoration, but also are easy to prepare, process and store.
Disclosure of Invention
The invention aims to provide a dressing with antibacterial and moisturizing functions and a preparation method thereof.
The invention is realized by the following technical scheme:
the dressing with the antibacterial and moisturizing functions is characterized by being prepared from the following raw materials: the dressing with the antibacterial and moisturizing functions is prepared by uniformly coating the mixture B on the dressing body.
The dressing with the antibacterial and moisturizing functions is characterized in that the dressing body is a fabric made of chemical short fibers.
The dressing with the antibacterial and moisturizing functions is characterized in that the dressing body is a woven product made of cotton fibers, fibrilia or alginic acid fibers after spinning, and is sheet-shaped.
The dressing with the antibacterial and moisturizing functions, wherein the molecular weight of the hyaluronic acid is 1000000 ～ 1800000.
The dressing with the antibacterial moisturizing function is characterized in that the antibacterial peptide is selected from antibacterial peptide DC.
A preparation method of a dressing with antibacterial and moisturizing functions, which comprises the following steps:
s110, adding 98.5-99.5% of purified water, 0.0008-0.0025% of tea polyphenol, 0.06-0.2% of hyaluronic acid, 0.001-0.05% of oligopeptide-1 and 0.001-0.05% of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
s120, continuously inputting medical ozone into the mixture A so as to dissolve the medical ozone into the mixture A;
s130, detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when the content of ozone in the mixture A reaches 0.6g/L-1g/L to obtain a mixture B;
and S140, uniformly coating the mixture B on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
The preparation method of the dressing with the antibacterial and moisturizing functions comprises the step of mixing the mixture B at a concentration of 0.03-0.25ml/cm 2 The amount of the coating agent is uniformly coated on the dressing body.
The preparation method of the dressing with the antibacterial and moisturizing functions, wherein the continuous input of the medical ozone into the mixture A so as to dissolve the medical ozone into the mixture A, comprises the following steps:
medical ozone is continuously fed into the mixture A at a temperature of 20-28 ℃ and a pressure of 1-1.6 atm to dissolve the medical ozone in the mixture A.
The preparation method of the dressing with the antibacterial and moisturizing functions comprises the step of preparing purified water, wherein the purified water is deionized water.
Compared with the prior art, the invention has the following outstanding advantages and effects:
on one hand, the dressing with the antibacterial and moisturizing functions can be applied to the skin surface of a human body to perform bacteriostasis, moisturizing and cleaning on the skin surface, and can generate good bacteriostasis effects on staphylococcus, streptococcus, propionic acid bacteria and corynebacteria after about 20 minutes of action. The using method comprises the following steps: the dressing is applied on the skin surface of the human body, and the use is very convenient.
On the other hand, the dressing with the antibacterial and moisturizing functions provided by the invention can be stored for a long time without affecting the efficacy.
Drawings
Fig. 1 is a schematic view of the effect of a dressing with antibacterial and moisturizing functions and a preparation method thereof.
Fig. 2 is a schematic diagram showing the effect of a dressing with antibacterial and moisturizing functions and a preparation method thereof.
Fig. 3 is a schematic view showing the effect of a dressing with antibacterial and moisturizing functions and a preparation method thereof.
Detailed Description
The invention is further described below in connection with the specific embodiments, but is not to be construed as being limited in any way, and any modifications which are within the scope of the appended claims are intended to remain within the scope of the invention.
Example 1
As shown in fig. 1, a preparation method of a dressing with antibacterial and moisturizing functions is as follows:
adding 1.995kg of purified water, 0.04g of tea polyphenol, 3g of hyaluronic acid, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Example 2
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.997kg of purified water, 0.02g of tea polyphenol, 2g g of hyaluronic acid, 0.49g of oligopeptide-1 and 0.49g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Example 3
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.9968kg of purified water, 0.04g of tea polyphenol, 1.2 g of hyaluronic acid, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Example 4
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.994kg of purified water, 0.04g of tea polyphenol, 4g of hyaluronic acid, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Example 5
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.995kg of purified water, 0.04g of tea polyphenol, 3g of hyaluronic acid, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.0 atmosphere pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when the content of ozone in the mixture A reaches 0.8g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Example 6
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.995kg of purified water, 0.04g of tea polyphenol, 3g of hyaluronic acid, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.25ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Comparative example 1
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.995kg of purified water, 0.04g of tea polyphenol, 3g of hyaluronic acid, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
the mixture A without ozone is added at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Comparative example 2
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.997kg of purified water, 0.04g of tea polyphenol, 0.98g of oligopeptide-1 and 0.98g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Comparative example 3
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.996kg of purified water, 0.04g of tea polyphenol, 3g of hyaluronic acid and 0.96 g of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Comparative example 4
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.996kg of purified water, 0.04g of tea polyphenol, 3g of hyaluronic acid and 0.96 g of oligopeptide-1 into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Comparative example 5
A preparation method of dressing with antibacterial and moisturizing functions comprises the following steps:
adding 1.997kg of purified water, 0.04g of tea polyphenol and 2.96g of hyaluronic acid into a stirring tank according to the following mass percent, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A, and dissolving the medical ozone into the mixture A under the environment of 25 ℃ and 1.5 atmospheric pressure;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when detecting that the content of ozone in the mixture A reaches 1g/L to obtain a mixture B;
the mixture B was stirred at 0.15ml/cm 2 The amount of the composition is uniformly coated on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
Antibacterial performance test:
experimental materials
And (3) strain: coli, staphylococcus aureus, streptococcus albus, agrobacterium green.
Comparative test materials: the dressings of examples 1 to 6 and comparative examples 1, 3, 4 and 5 (dressing in a round shape with a diameter of 10 mm) were prepared by dispensing the nutrient medium added with the nutrient components into sterilized dishes, 95% alcohol, inoculating loop, forceps, alcohol lamp.
The experimental contents are as follows:
the operation method comprises the following steps: taking a bacterial liquid containing any strain, immersing the bacterial liquid with a sterilized inoculating loop, and densely streaking (repeatedly streaking or cross streaking) the inoculating loop on the surface of a culture medium in a culture dish. Each dressing was separately applied to the surface of the culture medium using sterile forceps, with only one dressing placed in each dish. Each dressing can be correspondingly provided with a plurality of culture dishes, and the average value of the culture dishes is the average value result corresponding to the dressing. Each of the dishes was incubated at room temperature (25 ℃) for 48 hours, and the test results obtained are shown in FIG. 2.
Moisture retention performance test:
experimental materials
Comparative test materials: the dressings of examples 1-6 and comparative example 2 (dressing round, diameter slightly smaller than the dish inside diameter) were pre-placed in a 60 ℃ oven for 30 minutes to dry the water, 95% alcohol, tweezers in the dish.
The experimental contents are as follows:
the operation method comprises the following steps: the dressings were placed separately in petri dishes using sterile forceps, with only one dressing placed in each dish. Each dressing can be correspondingly provided with a plurality of culture dishes, and the average value of the culture dishes is the average value result corresponding to the dressing. Each of the dishes was left to stand at normal temperature (25 ℃) for 24 hours, and since the dressing in each dish volatilized moisture when left standing, the weight lost by the dressing in each dish was measured as the moisture volatilized by the corresponding dressing, and the test results are shown in fig. 3.
Because the dressing body is flaky, the manufactured dressing with the antibacterial and moisturizing functions is flaky, and the dressing is packaged and stored by adopting a sealing bag after being manufactured, and the dressing is used by disassembling the sealing bag. The dressing body can be set into a facial mask shape, so that the dressing can be adhered to the face of a human body to moisturize and degerming the face; the dressing body is arranged in a strip shape or a belt shape, so that the dressing can be attached to the palm, the arm, the back, the thigh, the shank and the abdomen of a human body to keep moisture and sterilize the corresponding parts.
The ozone and the antibacterial peptide contained in the dressing are matched with each other, so that good sterilization and bacteriostasis effects can be achieved, the hyaluronic acid is also called hyaluronic acid, has strong water-retaining capacity, and the hyaluronic acid with the molecular weight of 1000000 ～ 1800000 is added into the mixture B to prepare the dressing, so that the dressing has good effects of moisturizing skin and can prevent skin from being cracked and aged; the antibacterial peptide precursor refers to an alkaline polypeptide substance with antibacterial activity, which is generated by induction in an insect body, can be prepared by a biological fermentation mode, has the molecular weight of about 2000-7000, is composed of 20-60 amino acid residues, and has the characteristics of strong alkalinity, thermal stability, broad-spectrum antibacterial property and the like; oligopeptide-1 is a polymer composed of glycine, histidine and lysine, and has the function of conditioning human skin.
In a specific embodiment, the dressing body can also be made of a fabric made of the alginic acid fiber after spinning, the fabric made of the alginic acid fiber has an excellent water absorption effect, and compared with the dressing body made of common materials, the fabric made of the alginic acid fiber with unit mass can absorb more mixture B.
The dressing with the antibacterial and moisturizing functions can be applied to the skin surface of a human body to perform bacteriostasis, moisturizing and cleaning on the skin surface, has good bacteriostasis effects on staphylococcus, streptococcus, propionic acid bacteria and corynebacteria after about 20 minutes of action, has the moisturizing and moisturizing functions of the traditional skin care product, also has the bacteriostasis and moisturizing functions, and has good antibacterial and moisturizing effects. The using method comprises the following steps: the dressing is applied on the skin surface of the human body, and the use is very convenient.
Claims (9)
1. The dressing with the antibacterial and moisturizing functions is characterized by being prepared from the following raw materials: the dressing with the antibacterial and moisturizing functions is prepared by uniformly coating the mixture B on the dressing body, wherein the content of ozone in the mixture B is 0.6g/L-1g/L.
2. The dressing with antibacterial and moisturizing functions according to claim 1, wherein the dressing body is a woven fabric made of chemical short fibers.
3. The dressing with antibacterial and moisturizing functions according to claim 2, wherein the dressing body is a woven fabric made of cotton fibers, fibrilia or alginic acid fibers after spinning, and the dressing body is sheet-shaped.
4. The dressing having an antibacterial moisturizing function according to claim 1, wherein the molecular weight of the hyaluronic acid is 1000000 ～ 1800000.
5. The dressing having an antibacterial moisturizing function according to claim 1, wherein the antibacterial peptide is selected from housefly antibacterial peptides.
6. The preparation method of the dressing with the antibacterial and moisturizing functions is characterized by comprising the following steps of:
adding 98.5-99.5% of purified water, 0.0008-0.0025% of tea polyphenol, 0.06-0.2% of hyaluronic acid, 0.001-0.05% of oligopeptide-1 and 0.001-0.05% of antibacterial peptide into a stirring tank according to the following mass percentage, and obtaining a mixture A with uniform texture through the stirring action of the stirring tank;
continuously inputting medical ozone into the mixture A so that the medical ozone is dissolved in the mixture A;
detecting the content of ozone in the mixture A in real time, and stopping inputting medical ozone when the content of ozone in the mixture A reaches 0.6g/L-1g/L to obtain a mixture B;
and uniformly coating the mixture B on the dressing body to obtain the dressing with the antibacterial and moisturizing functions.
7. The method for preparing a dressing having an antibacterial and moisturizing function according to claim 6, wherein the mixture B is uniformly coated on the dressing body in an amount of 0.03-0.25ml/cm 2.
8. The method for preparing a dressing having an antibacterial moisturizing function according to claim 6, wherein the continuous input of the medical ozone into the mixture a to dissolve the medical ozone in the mixture a comprises:
medical ozone is continuously fed into the mixture A at a temperature of 20-28 ℃ and a pressure of 1-1.6 atm to dissolve the medical ozone in the mixture A.
9. The method for preparing a dressing with antibacterial and moisturizing functions according to claim 6, wherein the purified water is deionized water.
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| CN110935056A (en) * | 2019-12-30 | 2020-03-31 | 山东星之诚生物科技有限公司 | Preparation method of alginate dressing with high hygroscopicity |
| CN115606596B (en) * | 2022-11-02 | 2024-02-23 | 中国石油大学(华东) | Reticular antibacterial material, preparation method and application thereof |
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| CN103536960A (en) * | 2013-10-30 | 2014-01-29 | 无锡灵锡医疗器械科技有限公司 | Hydrogel capable of slowly releasing antibacterial peptide as well as preparation method thereof |
| CN107007876A (en) * | 2017-06-02 | 2017-08-04 | 江苏昌吉永生物科技股份有限公司 | Hyaluronic acid medical aseptic dressing and preparation method thereof |
| CN107648205A (en) * | 2017-10-19 | 2018-02-02 | 北京九鼎君健医药科技项城有限公司 | A kind of collagen peptide dressing for promoting wound healing and preparation method thereof |
| CN108653713A (en) * | 2018-06-12 | 2018-10-16 | 广西庆翠堂生物科技有限责任公司 | A kind of natural composite antibacterial composition and preparation method thereof containing Tea Saponin |
| CN109106979A (en) * | 2018-09-11 | 2019-01-01 | 吉林省蓝鼎陆和科技有限公司 | A kind of tridecanoic peptide antiseptic dressing and preparation method thereof |
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