CN101324029A - A kind of antibacterial and hydrophilic nonwoven fabric and its preparation method and application - Google Patents

Abstract

The invention discloses an antibacterial and hydrophilic non-woven fabric, which is coated with silk protein and chitin; also discloses a method for preparing the non-woven fabric, comprising the following steps: 20 At a temperature of ℃ to 40 ℃, the nonwoven fabric is dipped twice and rolled twice in the finishing solution containing silk protein and chitin, and then baked and fixed under the condition of <160 ℃. In the nonwoven fabric of the present invention, the surface of the nonwoven fabric is coated with fibroin and chitin, so that the nonwoven fabric has hydrophilic, antibacterial and bactericidal effects, and has no obvious influence on the appearance of the nonwoven fabric. The prepared non-woven fabric can be used as disposable medical and sanitary materials.

Description

A kind of antibacterial and hydrophilic nonwoven fabric and its preparation method and application

technical field

The invention belongs to the field of functional materials, and in particular relates to an antibacterial and hydrophilic nonwoven fabric, a preparation method and application thereof.

Background technique

Due to the processing characteristics and product cost of some medical and sanitary nonwovens, synthetic fibers such as polyester and polypropylene have been mostly used for a long time, resulting in poor hydrophilicity of the product; It has very high antibacterial requirements. Therefore, it is imperative to develop nonwovens for medical and sanitary use with hydrophilic and antibacterial properties.

Improving the hydrophilic and antibacterial properties of nonwovens and fibers can be carried out through physical and chemical methods, such as raw silk modification, surface graft modification, functional finishing (such as padding or dipping), etc. Among them, the functional finishing method is simple and low-cost, and can increase its hygroscopicity, water absorption and antibacterial properties on the basis of basically maintaining the original characteristics of nonwovens, so it has become a more common method. However, there is a problem of poor durability in functional finishing.

Medical and sanitary nonwovens include disinfectant wipes, wound dressings, hemostatic patches, bandages, gauze balls, ointment cloths, absorbent pads, etc., as well as disposable materials such as baby diapers, women's sanitary napkins, and adult incontinence pads. Among them, disposable nonwovens do not require high durability.

Silk is solidified by the silk fluid secreted by cooked silkworms when they make cocoons. It is composed of two proteins: silk fibroin in the center and sericin surrounding it. In the past, when it was applied to clothing materials, in order to produce the unique luster and feel of silk, most of the sericin was removed during the scouring process, and silk fibroin was mainly used; sericin was stably separated from the scouring waste liquid and refined , At present, this technology has matured and reached industrialization. Silk fiber has good air permeability and excellent hygroscopicity. It contains 18 kinds of amino acids that are of great nutritional value to the human body. It can be used in clinical medicine and can be made into artificial blood vessels; in the field of non-woven fabrics, it can be used as medical dressings for burns Wound coverings that aid in wound healing, also known as "artificial skin". The main component of sericin is serine, in addition to aspartic acid, glutamic acid, alanine, glycine. Serine is a component of the natural moisturizing factor in the skin. It has a good affinity for the skin and has the effect of inhibiting the formation of skin wrinkles. Japanese dermatologists treated bras with high-purity sericin. Tests have proved that sericin It has a good effect on characteristic dermatitis.

Chitosan, also known as deacetylated chitin, polyglucosamine, and soluble chitin, is a biomacromolecule transformed from chitin through deacetylation reaction. Chitin, also known as chitin, chitin, crab shellin, polyacetylglucosamine, etc., is a linear amino polysaccharide that maintains and protects the bodies of crustaceans and microorganisms, and is widely found in arthropods (spiders, crustaceans, etc.) class) in the wings or shells. Chitosan and its derivatives have excellent broad-spectrum antibacterial properties. At the same time, chitosan has good hygroscopicity, biocompatibility and biodegradability. The degradation products generally have no toxic side effects on the human body, do not accumulate in the body, and have no immunity. Therefore, it has a very broad prospect in the field of biomedicine. Examples of developed and potential applications include artificial skin (wound dressings), surgical sutures and bone repair materials, anticoagulants and artificial dialysis membranes, pharmaceutical formulations and drug release agents, etc.

Contents of the invention

The purpose of the present invention is to overcome the deficiencies in the prior art and provide an antibacterial and hydrophilic non-woven fabric, which is coated with silk protein and chitin.

The silk protein is silk fibroin or sericin.

The chitin is a chitin with a degree of deacetylation>90%.

The nonwoven fabric is polypropylene spunbonded nonwoven fabric, polyester spunlace nonwoven fabric, polyester spunbonded nonwoven fabric or viscose/polyester spunlace nonwoven fabric.

The present invention also provides a method for preparing the above-mentioned nonwoven fabric, which includes the following steps: at a temperature of 20°C to 40°C, double-dipping and second-rolling the nonwoven fabric in a finishing solution containing silk protein and chitin Finally, it is baked and fixed under the condition of <160°C.

Described finishing solution also contains formaldehyde-free binder, and its each component and percentage by weight are:

Silk protein 0.5～5%

Chitin 0.5～5%

Formaldehyde-free binder 5～20%

The balance is water.

The chitin is the chitin dissolved in <1% acetic acid aqueous solution.

The nonwoven fabric of the present invention is used for disposable medical and sanitary materials.

The present invention has the following beneficial effects: the nonwoven fabric of the present invention, by coating the surface of the nonwoven fabric with silk protein and chitin, makes the nonwoven fabric have hydrophilic, antibacterial and bactericidal effects, and has no effect on the appearance of the nonwoven fabric. obvious impact. The prepared non-woven fabric can be used as disposable medical and sanitary materials.

Detailed ways

The technical scheme of the present invention is described below in conjunction with embodiment:

The invention relates to an antibacterial and hydrophilic nonwoven fabric, which is coated with silk protein and chitin. Silk protein is silk fibroin or sericin. Chitin is chitin with deacetylation degree>90%.

Embodiment 1,

The polypropylene spunbonded nonwoven fabric is subjected to two dipping and two rolling through the padding tank of the finishing solution. The contents of chitin and silk fibroin in the finishing solution are both 1%, the WH binder is 5%, and the bath ratio is 1:50 , the temperature is 25°C, the rolling ratio is 100%, then pre-baked (70°C), and baked (130°C). The nonwoven fabric can effectively kill 83.4% of Escherichia coli E.coli and 80.6% of Staphylococcus aureus S.aureus, and the hydrophilicity has increased by 4.6 times.

Antibacterial test method:

Take functionally finished non-woven fabrics and unfinished non-woven fabrics with a diameter of 1 cm, sterilize with ultraviolet radiation (irradiation time is 30 minutes), soak in sterile water; put the samples into sterile cell culture dishes respectively Then add 50 microliters of bacterial culture solution (10 ⁶ CFU/ml) and incubate in a 37°C incubator for 2 hours; add 1ml of phosphate buffer solution to the petri dish and clean it with ultrasonic waves (64kHz, 2 minutes ), and then take 50 microliters of gradient dilutions, add 50 microliters of bacterial buffers of different dilutions to the petri dish, spread the bacterial solution evenly on the solid agar medium with a coating stick, and place it at 37 °C Cultivate in an incubator for 24 hours; calculate the antibacterial ability of the sample according to the number of colonies on the solid agar medium.

Hydrophilic test method:

According to the "People's Republic of China Professional Standard Textile Capillary Effect Test Method (FZ/T01071-1999)", cut the nonwoven fabric after functional finishing and the nonwoven fabric sample without finishing, 30cm long and 3cm wide. Place the sample in the standard atmospheric condition with a temperature of 20±2°C and a relative humidity of 65%±3% for 24 hours, then place it vertically in the fabric capillary effect instrument, the water temperature is 27°C±2°C, the length of the sample into the water is 30mm, 30min Immediately after that, measure the seepage height of each sample strip, and calculate the degree of increase in hydrophilicity. The test is carried out under standard atmospheric conditions with a temperature of 20±2°C and a relative humidity of 65%±3%.

Example 2:

The polyester spunlaced nonwoven fabric is subjected to two dipping and two rolling through the padding tank of the finishing solution. The content of chitin in the finishing solution is 2%, the content of sericin is 5%, the WH binder is 10%, and the liquor ratio is 1 : 50, the temperature is 20°C, the scrap rate is 100%, then prebaked (70°C), and baked (125°C). The nonwoven fabric can effectively kill 85.7% of Escherichia coli E.coli and 82.3% of Staphylococcus aureus S.aureus, and the hydrophilicity has increased by 6.9 times.

Example 3:

The 70/30 viscose/polyester spunlaced nonwoven fabric is subjected to two dipping and two rolling through the padding tank of the finishing solution. The content of chitin in the finishing solution is 5%, the content of silk fibroin is 3%, and the WH binder is 10 %, the bath ratio is 1:50, the temperature is 40°C, the rolling ratio is 100%, then pre-baked (70°C), and baked (155°C). The nonwoven fabric can effectively kill 88.1% of Escherichia coli E.coli and 86.3% of Staphylococcus aureus S.aureus, and the hydrophilicity has increased by 4.2 times.

Example 4:

The polyester spunbonded nonwoven fabric is subjected to two dipping and two rolling through the padding tank of the finishing solution. The content of chitin in the finishing solution is 5%, the content of sericin is 5%, the WH adhesive is 20%, and the liquor ratio is 1 : 50, the temperature is 30°C, the scrap rate is 100%, then pre-baked (70°C), and baked (140°C). The nonwoven fabric can effectively kill 87.2% of Escherichia coli E.coli and 86.5% of Staphylococcus aureus S.aureus, and the hydrophilicity has increased by 7.6 times.

Finally, it should also be noted that the above examples are only specific implementation examples of the present invention. Apparently, the present invention is not limited to the above examples, and many variations are possible. All deformations that can be directly derived or associated by those skilled in the art from the content disclosed in the present invention should be considered as the protection scope of the present invention.

Claims (8)

1, a kind of have an antibiotic and hydrophilic non-weaving cloth, it is characterized in that: be coated with fibroin and chitin on the described non-weaving cloth.

2, non-weaving cloth according to claim 1 is characterized in that: described fibroin is fibroin albumen or sericin.

3, non-weaving cloth according to claim 1 is characterized in that: described chitin is the chitin of deacetylation＞90%.

4, non-weaving cloth according to claim 1 is characterized in that: described non-weaving cloth is polypropylene spunbond non-weaving cloth, terylene hydro-entangled non-woven fabric, terylene spun-bonded non-weaving cloth or viscose glue/terylene hydro-entangled non-woven fabric.

5, a kind of method for preparing the described non-weaving cloth of claim 1, it is characterized in that may further comprise the steps: under 20 ℃～40 ℃ temperature, with non-weaving cloth in the dressing liquid that contains fibroin and chitin two soak two roll after, under＜160 ℃ condition, bake set.

6, the preparation method of non-weaving cloth according to claim 5 is characterized in that: described dressing liquid also contains formaldehyde binder, and its each component reaches and is by weight percentage:

Fibroin 0.5～5%

Chitin 0.5～5%

Formaldehyde binder 5～20%

Its surplus is a water.

7, according to the preparation method of claim 5 or 6 described non-weaving cloths, it is characterized in that: described chitin is to be dissolved in＜chitin in 1% the aqueous acetic acid.

8, the described non-weaving cloth of claim 1 is used for promptly abandoning medical and health.