CN110123650A - A kind of dressing and preparation method thereof with anti-bacteria wet keeping function - Google Patents
A kind of dressing and preparation method thereof with anti-bacteria wet keeping function Download PDFInfo
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- CN110123650A CN110123650A CN201910347702.XA CN201910347702A CN110123650A CN 110123650 A CN110123650 A CN 110123650A CN 201910347702 A CN201910347702 A CN 201910347702A CN 110123650 A CN110123650 A CN 110123650A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The dressing and preparation method thereof with anti-bacteria wet keeping function that the present invention relates to a kind of, the dressing with anti-bacteria wet keeping function is prepared from the following materials: mixture B and dressing ontology, the mixture B includes pure water, ozone, tea polyphenols, hyaluronic acid, oligopeptides -1 and antibacterial peptide, the dressing ontology is to be made into object by what staple fibre was made, the mixture B is evenly applied to the dressing with anti-bacteria wet keeping function can be obtained on the dressing ontology.Dressing with anti-bacteria wet keeping function of the invention, human skin surface can be spread on for carrying out antibacterial, moisturizing, cleaning to skin surface, good fungistatic effect can be generated to staphylococcus, streptococcus, bacterium acidi propionici and corynebacteria, in addition to having the function of replenishing water and preserving moisture possessed by traditional skin care product, also have the function of antibacterial, sterilization, there is good anti-bacteria wet keeping effect.
Description
Technical field
The present invention relates to medical and beauty treatment technical field more particularly to a kind of dressing and its preparation with anti-bacteria wet keeping function
Method.
Background technique
With the gradually development of beauty industry, modern female is increasingly focused on maintaining skin, more and more people
Selection is using skin care item to achieve the purpose that skin care, beauty.
On the one hand, the skin care item such as existing facial mask, water and milk replenishing water and preserving moisture function is not good enough and lacks the effective degerming function of strength
Can, or only focus on wherein one side function.When face or the infection of other area skins, need to carry out the bacterium on skin
It removes to reduce the risk of skin infection, traditional skin care item show slightly out of strength in this respect.On the other hand, to protect a product from
Microbial contamination is rotten, extends the shelf life of product, and commonly using addition preservative in the prior art prevents the breeding of microorganism, but
The addition of preservative will increase the irritation to skin, and skin is caused the sensitization phenomenon of flush, erythema occur.And derive from animal
In antibacterial peptide then can not only make mask product that there is preferable antibacterial skin effect but also holding time and the effect of product can be extended.
Plant extracts has effects that allergy is repaired and is not easy in inborn moisturizing, mostly uses plant to improve facial mask effect
The prescription that extract and compound combine.But component is various to be easy to interfere with each other, and can not only reduce effect can also cause other
It is difficult to expect problem.
Therefore, need a facial mask and preparation method thereof for having both antibacterial and moisture-keeping functions, both can effectively have both moisturizing and
The function of antibacterial reparation, and easily prepared, processing and preservation.
Summary of the invention
The dressing and preparation method thereof with anti-bacteria wet keeping function that the technical problem to be solved in the present invention is to provide a kind of.
The present invention is achieved through the following technical solutions:
A kind of dressing with anti-bacteria wet keeping function, which is characterized in that be prepared from the following materials: mixture B and dressing sheet
Body, the mixture B include pure water, ozone, tea polyphenols, hyaluronic acid, oligopeptides -1 and antibacterial peptide, and the mixture B is equal
The dressing with anti-bacteria wet keeping function can be obtained in even be coated on the dressing ontology.
The dressing with anti-bacteria wet keeping function, wherein the dressing ontology is to be made by staple fibre
Made of be made into object.
The dressing with anti-bacteria wet keeping function, wherein the dressing ontology is by cotton fiber, flaxen fiber or seaweed
What sour fiber was made after spinning is made into object, and the dressing ontology is sheet.
The dressing with anti-bacteria wet keeping function, wherein the molecular weight of the hyaluronic acid be 1000000~
1800000。
The dressing with anti-bacteria wet keeping function, which is characterized in that the antibacterial peptide is selected from antibacterial peptide DC.
A kind of preparation method of the dressing with anti-bacteria wet keeping function, comprising the following steps:
S110, according to following mass percent by pure water 98.5-99.5%, tea polyphenols 0.0008%-0.0025%, 0.06%-
0.2% hyaluronic acid, 0.001%-0.05% oligopeptides -1 and 0.001%-0.05% antibacterial peptide are added in agitator tank, pass through agitator tank
Stirring action obtains homogeneous mixture A；
S120, medical ozone is continued to input the mixture A so that the medical ozone is dissolved in the mixture A；
S130, the content of ozone in the mixture A is measured in real time, when detecting ozone content in the mixture A
Stop input medical ozone when reaching 0.6g/L-1g/L, obtains mixture B；
S140, the mixture B is evenly applied on the dressing ontology, obtains the dressing with anti-bacteria wet keeping function.
The preparation method of the dressing with anti-bacteria wet keeping function, wherein the mixture B is with 0.03-0.25ml/
cm2Dosage be evenly applied on the dressing ontology.
The preparation method of the dressing with anti-bacteria wet keeping function, wherein described to continue medical ozone to input institute
Mixture A is stated so that the medical ozone is dissolved in the mixture A, comprising:
In the environment that temperature is 20-28 DEG C, pressure is 1-1.6 atmospheric pressure, by medical ozone continue to input the mixture A with
It is dissolved in the medical ozone in the mixture A.
The preparation method of the dressing with anti-bacteria wet keeping function, wherein the pure water is deionized water.
Compared with prior art, the present invention has the advantages that following prominent and effect:
On the one hand, the dressing with anti-bacteria wet keeping function of the invention, can spread on human skin surface for skin surface into
Row antibacterial, moisturizing, cleaning, effect 20 minutes or so can generate staphylococcus, streptococcus, bacterium acidi propionici and corynebacteria good
Good fungistatic effect also has the function of antibacterial, sterilization in addition to having the function of replenishing water and preserving moisture possessed by traditional skin care product,
With good anti-bacteria wet keeping effect.Application method: taking dressing to spread on human skin surface, and use is very convenient.
On the other hand, the dressing provided by the invention with anti-bacteria wet keeping function can save for a long time, and will not influence
Its effect.
Detailed description of the invention
Fig. 1 is a kind of effect diagram of dressing with anti-bacteria wet keeping function of the invention and preparation method thereof.
Fig. 2 is a kind of effect diagram of dressing with anti-bacteria wet keeping function of the invention and preparation method thereof.
Fig. 3 is a kind of effect diagram of dressing with anti-bacteria wet keeping function of the invention and preparation method thereof.
Specific embodiment
With reference to embodiment, the invention will be further described, but does not constitute to any limit of the invention
System, the modification of any limited times made in scope of the invention as claimed, still in scope of the presently claimed invention.
Embodiment 1
As shown in Figure 1, a kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.995kg, tea polyphenols 0.04g, 3g hyaluronic acid, 0.98g oligopeptides -1 and 0.
98g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Embodiment 2
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.997kg, tea polyphenols 0.02g, 2 g hyaluronic acids, 0.49g oligopeptides -1 and
0.49g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Embodiment 3
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.9968kg, tea polyphenols 0.04g, 1.2 g hyaluronic acids, 0.98g oligopeptides -1
And 0.98g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Embodiment 4
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.994kg, tea polyphenols 0.04g, 4g hyaluronic acid, 0.98g oligopeptides -1 and
0.98g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Embodiment 5
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.995kg, tea polyphenols 0.04g, 3g hyaluronic acid, 0.98g oligopeptides -1 and 0.
98g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.0 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 0.8g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Embodiment 6
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.995kg, tea polyphenols 0.04g, 3g hyaluronic acid, 0.98g oligopeptides -1 and 0.
98g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.25ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Comparative example 1
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
According to following mass percent by pure water 1.995kg, tea polyphenols 0.04g, 3g hyaluronic acid, 0.98g oligopeptides -1 and 0.
98g antibacterial peptide is added in agitator tank, obtains homogeneous mixture A by the stirring action of agitator tank；
By the mixture A for being not added with ozone with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain
Dressing with anti-bacteria wet keeping function.
Comparative example 2
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
Pure water 1.997kg, tea polyphenols 0.04g, 0.98g oligopeptides -1 and 0. 98g antibacterial peptide are added according to following mass percent
Enter in agitator tank, homogeneous mixture A is obtained by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Comparative example 3
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
Pure water 1.996kg, tea polyphenols 0.04g, 3g hyaluronic acid and 0. 96g antibacterial peptide are added according to following mass percent
Enter in agitator tank, homogeneous mixture A is obtained by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Comparative example 4
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
Pure water 1.996kg, tea polyphenols 0.04g, 3g hyaluronic acid and 0. 96g oligopeptides -1 are added according to following mass percent
Enter in agitator tank, homogeneous mixture A is obtained by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Comparative example 5
A kind of dressing with anti-bacteria wet keeping function the preparation method is as follows:
Pure water 1.997kg, tea polyphenols 0.04g and 2.96g hyaluronic acid are added in agitator tank according to following mass percent,
Homogeneous mixture A is obtained by the stirring action of agitator tank；
Medical ozone is continued to input the mixture A, makes institute in the environment of temperature is 25 DEG C, pressure is 1.5 atmospheric pressure
Medical ozone is stated to be dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 1g/L, obtains mixture B；
By the mixture B with 0.15ml/cm2Dosage be evenly applied on the dressing ontology, obtain with anti-bacteria wet keeping
The dressing of function.
Anti-microbial property test:
Experimental material
Strain: Escherichia coli, staphylococcus aureus, streptococcus albus, green Agrobacterium.
Comparative test material: the dressing (dressing of embodiment 1-6 and comparative example 1, comparative example 3, comparative example 4 and comparative example 5
For circle, diameter 10mm), the culture medium for adding nutritional ingredient is sub-packed in sterilizes culture dish, 95% alcohol, oese, tweezer
Son, alcolhol burner.
Experiment content:
Operating method: taking the bacterium solution comprising any of the above-described strain, is dipped in bacterium solution with the oese after sterilizing, and by oese in
The surface compact scribing line (can cross or carry out the scribing line of " ten " font back and forth) of culture medium in culture dish.It will using aseptic nipper
Various dressing are covered on media surface respectively, only place a piece of dressing in each culture dish.Every kind of dressing can be correspondingly arranged
Multiple culture dishes, the mean value of multiple culture dishes are the corresponding mean value result of the dressing.Each culture dish is placed in room temperature (25 DEG C)
Lower culture 48h, test results are shown in figure 2 for gained.
Performance of keeping humidity test:
Experimental material
Comparative test material: the dressing (dressing is circle, and diameter is slightly less than culture dish internal diameter) of embodiment 1-6 and comparative example 2,
Culture dish is pre-placed in 60 DEG C of baking ovens 30 minutes to dry the moisture in culture dish, 95% alcohol, tweezers.
Experiment content:
Operating method: it takes and various dressing is respectively placed in culture dish using aseptic nipper, only placed in each culture dish
A piece of dressing.Every kind of dressing can be correspondingly arranged multiple culture dishes, and the mean value of multiple culture dishes is the corresponding mean value knot of the dressing
Fruit.Each culture dish is placed under room temperature (25 DEG C) and is stood for 24 hours, since dressing can volatilize moisture when standing in each culture dish,
Measuring the weight that dressing is lost in each culture dish is the moisture that corresponding dressing is volatilized, and test results are shown in figure 3 for gained.
Since dressing ontology is sheet, then the manufactured obtained dressing with anti-bacteria wet keeping function is also sheet, dressing
Pack preservation is carried out using hermetic bag after completing, when use dismantles hermetic bag.Dressing ontology can be set to facial mask
Shape, then dressing can be covered on human body face to carry out moisturizing degerming to face；Dressing ontology is set as strip or band, then dressing
The palm of human body, arm, back, thigh, shank, abdomen can be covered on to carry out moisturizing degerming to corresponding site.
Wherein, ozone included in dressing and antibacterial peptide cooperate, and can reach good degerming, fungistatic effect, thoroughly
Bright matter acid is also known as hyaluronic acid, with the stronger ability for keeping moisture content, uses molecular weight for 1000000~1800000
Hyaluronic acid be added in mixture B can have so that dressing is prepared to skin carry out moisturizing good result, can prevent
Only chapped skin, aging；Antibacterial peptide former refers to that the one kind generated in insect bodies through induction has the basic polypeptide object of antibacterial activity
Matter can be now prepared by way of biofermentation, and molecular weight is 2000~7000 or so, by 20~60 amino acid
Residue composition, has the characteristics that strong basicity, thermal stability and broad-spectrum antiseptic；Oligopeptides -1 is glycine and histidine and lysine
The polymer of composition has the function of being improved human skin.
In the particular embodiment, also can be used that alginic acid fibre is made after spinning is made into object as dressing sheet
Body, what alginic acid fibre was made is made into object with excellent soaking effect, compared to common material as dressing ontology, list
What the alginic acid fibre of position quality was made, which is made into object, can absorb more mixture B.
Dressing with anti-bacteria wet keeping function of the invention can spread on human skin surface for pressing down to skin surface
Bacterium, moisturizing, cleaning, effect 20 minutes or so can generate staphylococcus, streptococcus, bacterium acidi propionici and corynebacteria good
Fungistatic effect also has the function of antibacterial, sterilization, has in addition to having the function of replenishing water and preserving moisture possessed by traditional skin care product
Good anti-bacteria wet keeping effect.Application method: taking dressing to spread on human skin surface, and use is very convenient.
Claims (9)
1. a kind of dressing with anti-bacteria wet keeping function, which is characterized in that be prepared from the following materials: mixture B and dressing
Ontology, the mixture B includes pure water, ozone, tea polyphenols, hyaluronic acid, oligopeptides -1 and antibacterial peptide, by the mixture B
It is evenly applied to that the dressing with anti-bacteria wet keeping function can be obtained on the dressing ontology.
2. as described in claim 1 with the dressing of anti-bacteria wet keeping function, which is characterized in that the dressing ontology is by chemistry
What staple fiber was made is made into object.
3. as claimed in claim 2 with the dressing of anti-bacteria wet keeping function, which is characterized in that the dressing ontology is by cotton fibre
What dimension, flaxen fiber or alginic acid fibre were made after spinning is made into object, and the dressing ontology is sheet.
4. as described in claim 1 with the dressing of anti-bacteria wet keeping function, which is characterized in that the molecular weight of the hyaluronic acid
It is 1000000~1800000.
5. as described in claim 1 with the dressing of anti-bacteria wet keeping function, which is characterized in that the antibacterial peptide is anti-selected from housefly
Bacterium peptide.
6. a kind of preparation method of the dressing with anti-bacteria wet keeping function, which comprises the following steps:
It is according to following mass percent that pure water 98.5-99.5%, tea polyphenols 0.0008%-0.0025%, 0.06%-0.2% is transparent
Matter acid, 0.001%-0.05% oligopeptides -1 and 0.001%-0.05% antibacterial peptide are added in agitator tank, pass through the stirring action of agitator tank
Obtain homogeneous mixture A；
Medical ozone is continued to input the mixture A so that the medical ozone is dissolved in the mixture A；
The content of ozone in the mixture A is measured in real time, when detecting that ozone content reaches in the mixture A
Stop input medical ozone when 0.6g/L-1g/L, obtains mixture B；
The mixture B is evenly applied on the dressing ontology, the dressing with anti-bacteria wet keeping function is obtained.
7. the preparation method of the dressing according to claim 6 with anti-bacteria wet keeping function, which is characterized in that the mixing
Object B is with 0.03-0.25ml/cm2Dosage be evenly applied on the dressing ontology.
8. the preparation method of the dressing according to claim 6 with anti-bacteria wet keeping function, which is characterized in that described to cure
The mixture A is persistently inputted with ozone so that the medical ozone is dissolved in the mixture A, comprising:
In the environment that temperature is 20-28 DEG C, pressure is 1-1.6 atmospheric pressure, by medical ozone continue to input the mixture A with
It is dissolved in the medical ozone in the mixture A.
9. the preparation method of the dressing according to claim 6 with anti-bacteria wet keeping function, which is characterized in that described pure
Water is deionized water.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110935056A (en) * | 2019-12-30 | 2020-03-31 | 山东星之诚生物科技有限公司 | Preparation method of alginate dressing with high hygroscopicity |
| CN115606596A (en) * | 2022-11-02 | 2023-01-17 | 中国石油大学(华东) | Reticular antibacterial material, preparation method and application thereof |
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| CN109106979A (en) * | 2018-09-11 | 2019-01-01 | 吉林省蓝鼎陆和科技有限公司 | A kind of tridecanoic peptide antiseptic dressing and preparation method thereof |
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| CN103536960A (en) * | 2013-10-30 | 2014-01-29 | 无锡灵锡医疗器械科技有限公司 | Hydrogel capable of slowly releasing antibacterial peptide as well as preparation method thereof |
| CN107007876A (en) * | 2017-06-02 | 2017-08-04 | 江苏昌吉永生物科技股份有限公司 | Hyaluronic acid medical aseptic dressing and preparation method thereof |
| CN107648205A (en) * | 2017-10-19 | 2018-02-02 | 北京九鼎君健医药科技项城有限公司 | A kind of collagen peptide dressing for promoting wound healing and preparation method thereof |
| CN108653713A (en) * | 2018-06-12 | 2018-10-16 | 广西庆翠堂生物科技有限责任公司 | A kind of natural composite antibacterial composition and preparation method thereof containing Tea Saponin |
| CN109106979A (en) * | 2018-09-11 | 2019-01-01 | 吉林省蓝鼎陆和科技有限公司 | A kind of tridecanoic peptide antiseptic dressing and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110935056A (en) * | 2019-12-30 | 2020-03-31 | 山东星之诚生物科技有限公司 | Preparation method of alginate dressing with high hygroscopicity |
| CN115606596A (en) * | 2022-11-02 | 2023-01-17 | 中国石油大学(华东) | Reticular antibacterial material, preparation method and application thereof |
| CN115606596B (en) * | 2022-11-02 | 2024-02-23 | 中国石油大学(华东) | Reticular antibacterial material, preparation method and application thereof |
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