CN110075070A - Seven taste face networks of one kind lead to particle and preparation method thereof - Google Patents
Seven taste face networks of one kind lead to particle and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to the prescriptions of traditional Chinese medicine fields of facial paralysis, it discloses seven taste face networks of one kind and leads to particle and preparation method thereof, by 9~15 parts of Rhizoma Atractylodis Macrocephalae by weight of Chinese medicine former material, 6~14 parts of rhizoma typhonii, 8~14 parts of bombyx batryticatus, 3 parts of scorpio, 9~15 parts of Radix Angelicae Sinensis, 9~15 parts of radix paeoniae rubra and 9~15 parts of pheretima pulverize into powder after weighing, add and filtrate one is obtained by filtration after carrying out boiling water bath after water, the dregs of a decoction are being extracted to obtain filtrate two by ethyl alcohol, filtrate one and filtrate two obtain the extracting solution of effective component after mixing, heating extraction liquid is condensed into paste and use spray drying process be granulated by paste and drying forms particle.The present invention presses theory of traditional Chinese medical science prescription, breaks traditional medication taboo, and making it in a medicament has the benefits of strong flesh of resolving sputum invigorating the spleen, expelling wind and activating blood flow dredging collateral, dredges facial channels and collaterals therapeutic facial paralysis.
Description
Technical field
The present invention relates to the prescriptions of traditional Chinese medicine field of facial paralysis, specifically a kind of seven taste face network leads to particle and preparation method thereof.
Background technique
Peripheral facial paralysis, doctor trained in Western medicine is referred to as " Facial Paralysis ", with facial expression muscle movement dysfunction for it
Main clinical manifestation, be embodied in frown, close one's eyes, grinningly, drum cheek and the movements such as be in a pout cannot；There is distortion of commissure, volume line
Disappearance, widening of palpebral fissure, close that mesh is not tight, nasolabial groove shoals, rouses the cheek and leak, gargle leak phenomena such as, Chinese medicine is referred to as " mouth addiction " " mouth
Mesh is out-of-the-way " etc..The disease seriously affects the quality of life of patient, also brings immense pressure to the psychology of patient, and effective due to lacking
Therapeutic scheme easily makes patient lose treatment confidence, falls into the vicious circle for the treatment of.
Modern medicine thinks that peripheral facial paralysis is facial nerve acute edema in stylomastoid foramen, and facial nerve inflammation or facial nerve are pressurized
Caused lesion.The pathological change of facial paralysis is mainly facial nerve oedema, myelin swelling, depigmentation, or even can have different degrees of axis
Mutability.Its cause of disease and pathogenesis be not yet it is very clear, may with virus infection, autoimmunity, poor arterial inflow, environment damage
Harmful and heredity is related.
Peripheral facial paralysis belongs to Chinese medicine " facial paralysis " scope, and ancient times are also referred to as " facial paralysis ", what Miraculous Pivot was recorded: " mouth
", " mouth is out-of-the-way ", the names of disease such as " sudden facial distortion ", the earliest ancient Chinese physician that has recorded recognizes the difference of facial paralysis name of disease.In access
State's successive dynasties history medicine classical works, facial paralysis have different understanding in the period of different, and facial paralysis name of disease is also changeable." Synopsis Golden Chamber "
Cloud: " floating pulse indicating blood deficiency, collaterals being void and defenceless ... perverse trend is counter to be delayed, and healthy tendency is anxious ...It is out-of-the-way unsuccessful.", Zhang Zhongjing face paralysis is known as "It is out-of-the-way ", Sui's Chao Yuanfang (550-630 A.D.) thinks that face paralysis is " mouth eyeTiltedly ", " General Treatise on the Cause and Symptoms of Diseases air portWait " it carries: " ailment said due to cold or exposure enters sufficient sun
It is bright ... therefore make mouth eyeTiltedly." " Ling Shu Miraculous Pivot or Divine Axis muscles along the regular meridians " say that " then mouth mesh is out-of-the-way to bright, hand the sun ... the muscular contracture of sun of foot.The corner of the eyes is anxious then
It cannot finally regard." stomach channel of foot-Yang-ming and small intestine meridian are put forward for the first time as the disease position of facial paralysis." General Records of Holy Universal Relief wind is said " cloud: " foot
The bright arteries and veins of sun follows cheek vehicle, and the arteries and veins of the hand sun follows neck tempora.Two through all wind-engaging cold air.Muscular contracture draws cheek.Make us mouthIt is out-of-the-way ", follow
This two through muscles along the regular meridians by heresy, chill makes muscular contracture, draws one side cheek, and cause the viewpoint of sudden facial distortion.For the cause of disease disease of face paralysis
Machine, ancient literature has detailed elaboration, interior to be thought that ailment said due to cold or exposure wins and falls ill, and " sudden facial distortion, anxious person, mesh is not based on heresy Sheng more
It closes, hot then flaccidity of tendon and muscle, cheek muscle unable to open the eyes ..., which has, trembles with fear then suddenly, draws cheek and moves mouth.Having heat, then flaccidity of tendon and muscle is vertical, delays and is unequal to receiving, therefore out-of-the-way." main
It is to experience ailment said due to cold or exposure, ailment said due to cold or exposure invades head, and folder is cold then anxious, and tendon and vessel contracture, eye closing cannot.Then the slow inability of tendon and vessel, mesh close not folder heat
Energy." Lei Zheng Zhi Cai " is write by Qing Dynasty Lin Peiqin, thinks that the morbidity of facial paralysis is not caused by exopathogen, not mainly due to blood
Facial passages through which vital energy circulates can be supported and caused.It is evil not competent in healthy tendency is deposited.Famous doctor's Chao Yuanfang (550-630 A.D.) cloud " the hemiplegia mouth of Tang, SuiBe it is physically weak by
Wind, ailment said due to cold or exposure enter the muscle of cheek mouth ", it is indicated that physically weak and ailment said due to cold or exposure is all pathogenic factor.
The doctor trained in Western medicine of this disease is frequently with antiviral drugs and enough glucocorticoid treatments, and in addition neurotrophic agents, eye are used
The treatment means such as medicine, decompression, but produce effects and do not show, and with the toxic side effect of drug.Chinese medicine often takes acupuncture, physical therapy to control
It treats, but can only be respite pain by acupuncture, physical therapy treatment, curative effect can not be lasting, or even slightly starts to live after the treatment
Dynamic, local pain recurs at once.Therefore, the drug of a kind of expelling wind and activating blood flow, channels sootheing and network vessel quickening, the strong flesh of invigorating the spleen is needed, to realize facial paralysis
It is treated in time.
Summary of the invention
Based on problem above, the present invention provides seven taste face networks of one kind and leads to particle and preparation method thereof, and the present invention presses middle medical knowledge
By prescription, break traditional medication taboo, making it in a medicament has the benefits of strong flesh of resolving sputum invigorating the spleen, expelling wind and activating blood flow dredging collateral, dredges face
Portion's channels and collaterals therapeutic facial paralysis.
In order to solve the above technical problems, the present invention provides a kind of seven taste face networks to lead to particle, mainly by following dry weight part
Chinese medicine former material be made: 9~15 parts of Rhizoma Atractylodis Macrocephalae, 6~14 parts of rhizoma typhonii, 8~14 parts of bombyx batryticatus, 3 parts of scorpio, 9~15 parts of Radix Angelicae Sinensis, radix paeoniae rubra
9~15 parts and 9~15 parts of pheretima.
Have the beneficial effect that this product chooses seven taste natural traditional Chinese medicines, each bulk pharmaceutical chemicals synergistic effect plays strengthening the spleen and replenishing qi, heat-clearing
The effects of calming the liver, expelling wind and clearing away cold, acupuncture-stimulating blood stasis dispersing, relieving convulsion and spasm, replenishing and activating blood, simultaneous treatment of principal and subordinate symptoms is good to facial paralysis effect, nontoxic
Side effect.
In order to solve the above technical problems, the present invention also provides the preparation method that a kind of seven taste face networks lead to particle, this method
Include the following steps:
S1: by Chinese medicine former material by weight 9~15 parts of Rhizoma Atractylodis Macrocephalae, 6~14 parts of rhizoma typhonii, 8~14 parts of bombyx batryticatus, 3 parts of scorpio, when
Return 9~15 parts, 9~15 parts of radix paeoniae rubra and 9~15 parts of pheretima pulverize into powder after weighing, and be mixed into powder；
S2: powder in step S1 is put into container, 8~10 times of medicinal material total weight of water is added into container, by container
It is placed in boiling water bath and the dregs of a decoction and filtrate one is obtained by filtration after 2~3 hours；
S3: the obtained dregs of a decoction of step S2 are put into container, and the ethanol solution that 95% is added into container impregnates the dregs of a decoction
The dregs of a decoction are filtered off after 12 hours and obtain filtrate two, and wherein the additional amount of ethanol solution is 5 times of step S1 Chinese medicine total amount；
S4: it is added to the container and is mixed evenly after filtrate one and filtrate two are weighed, and is molten by the way that water or ethyl alcohol is added
The mass fraction that liquid adjusts ethyl alcohol in mixed solution is 60~65%, and extraction is obtained by filtration after mixed solution is stood 12 hours
Liquid；
S5: heating extraction liquid is condensed into paste；
S6: the paste in step S5 be granulated using spray drying process and drying forms particle；
S7: particle dry obtained in step S6 is subjected to package encapsulation with packaging bag.
Further, relative density is 1.25~1.30 when the paste in step S4 meets 60 DEG C.
Further, step S2, the filter progress in S3 and S4 is filtered using negative pressure film filter.
Further, it when extracting solution is concentrated in step S5, is recycled using ethyl alcohol of the condenser pipe to evaporation.
The logical beneficial effect of seven taste face networks made from this method is: in the method for the present invention, Chinese medicine former material being pulverized into powder, is had
Conducive to the dissolution of effective component in former material, extraction rate is fast；The dregs of a decoction after recycling alcohol solution dipping to decoct, make effective component
It is few to extract abundant, extraction recovery rate height, solvent consumption；Concentrated rear granulating and drying is at particle again, while remaining drug effect, also
Convenient for packing and transporting.
Detailed description of the invention
Seven taste face networks in Fig. 1 present invention lead to the preparation method flow chart of particle；
Fig. 2 is the structural schematic diagram of negative pressure film filter in embodiment 2；
Wherein: 1, orifice filter；2, pan is crossed；3, filter membrane；4, communicating pipe；5, filtrate collecting box；6, gas-guide tube；7, it is evacuated
Pump；8, valve；9, drain pipe.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention clearer, below with reference to embodiment and attached drawing, to this
Invention is described in further detail, and exemplary embodiment of the invention and its explanation for explaining only the invention, are not made
For limitation of the invention.
Embodiment 1:
A kind of seven taste face networks lead to particle, are mainly made by the Chinese medicine former material of following dry weight part: 9~15 parts of Rhizoma Atractylodis Macrocephalae, white attached
6~14 parts of son, 8~14 parts of bombyx batryticatus, 3 parts of scorpio, 9~15 parts of Radix Angelicae Sinensis, 9~15 parts of radix paeoniae rubra and 9~15 parts of pheretima.
Rhizoma Atractylodis Macrocephalae: bitter, it is sweet, it is warm-natured.Returns spleen, stomach meridian.With strengthening the spleen and replenishing qi, the effect of eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.Often
For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, threatened abortion.Its drug ingedient is containing in volatile oil, sequiterpene
Ester compounds, polyacetylene compound, Scopoletin, fructose, synanthrin and a variety of amino acid etc., have diuresis, it is hypoglycemic, strong,
Anticoagulation, the function of promoting hematopoiesis and protein synthesis；
Rhizoma typhonii: acrid flavour, it is warm-natured.Return stomach, Liver Channel.With wind-dispelling phlegm, the effect of arresting convulsion is jerked, detoxicating and resolving a mass, analgesic.For
Heap soil or fertilizer over and around the roots of apoplexy phlegm, mouth eyeTiltedly, dysphasia, infantile convulsion epilepsy, tetanus, phlegm and headache, migraine and general headache, scrofula subcutaneous nodule, poisonous snake sting
Wound.Its drug ingedient is containing cupreol, cupreol-D-Glucose glucoside, meso inositol, choline, uracil, succinic acid, cruel
Propylhomoserin, valine, palmitinic acid, linoleic acid, oleic acid, Trilinoleyl glyceride, glycerol-1,3-dipalmitate, Lectin From Typhonium Gigantumiengl etc.,
Have the function of anti-inflammatory, eliminating the phlegm, anti-tetanus etc..
Bombyx batryticatus: taste is salty, pungent, mild-natured.Return liver, lung, stomach meridian.With Inflammation Zhijing, the effect of wind-expelling pain-stopping, reducing phlegm and resolving masses.
Phlegm, twitch, acute infantile convulsion, tetanus, middle air port are pressed from both sides for liver windHeadache due to pathogenic wind-heat, hot eyes pharyngalgia, rubella itch, hair
Nourish mumps.Its drug ingedient melts hormone, ecdysone, ring acetal acid peptides, fat containing protein, amino acid, abnormal activity
Sour amide, lipoid etc. have anticonvulsion, syngignoscism.
Scorpio: acrid flavour, it is mild-natured.Return liver warp.It with relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, the effect of dispersing pathogen accumulation.For in liver wind
It is dynamic, spasm twitch, child convulsion, middle air portHemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.Its
Drug ingedient contains scorpion venom, propylhomoserin base acid, 29 kinds of inorganic elements, trimethylamine, glycine betaine, ammonium salt, picric acid azanol, cholesterol, ovum
Phosphatide, scorpion acid, taurine, palmitic acid, linolenic acid, behenic acid, positive 17 carbonic acid, vaccenic acid, 20 carbonic acid etc., it is insane with resisting
Epilepsy, anticonvulsion, antitumor and analgesic activity.
Radix Angelicae Sinensis: it is sweet in flavor, pungent, it is warm-natured.Return liver, the heart, the spleen channel.With replenishing and activating blood, the effect of regulating menstruation and relieving pain, moistening intestines and relaxing bowels.
For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, dry constipation of intestines, rheumatic arthralgia, injury from falling down,
Ulcer sores.Modern study proves that its have anti anoxia, adjust body's immunity, anticancer, cosmetology, replenishing and activating blood, it is antibacterial,
Anti arteriosclerosis effect.
Radix paeoniae rubra: bitter, cold nature.Return liver warp.With clearing heat and cooling blood, the effect of removing blood stasis and acesodyne.For thermal man's ying blood, epidemic heat syndrome
Macular eruption, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, amenorrhea and algomenorrhea, addiction lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore.This product can expand
It opens coronary artery, increase coronary blood flow；Radix paeoniae rubra Aqueous extracts, radix paeoniae rubra glycosides, radix paeoniae rubra ingredient and its derivative have inhibition platelet aggregation
Collection effect；The outer thrombosis time of its water decoction energy extension body, mitigates thrombus dry weight.Contained Paeoniflorin has calm, anti-inflammatory analgesic
Effect.Chinese herbaceous peony liquid extract, Paeoniflorin have anticonvulsant action.Radix paeoniae rubra, Paeoniflorin have spasmolysis；Conjunction of the radix paeoniae rubra to liver cell DNA
At there is apparent humidification, there is stronger inhibiting effect to multiple pathogenic microorganisms.
Pheretima: taste is salty, cold in nature.Return liver, stomach, lung, bladder meridian.With The flat liver of heat-clearing, relieving convulsion and spasm, relieving asthma, diuresis, dredging collateral
The effect of eliminating impediment.Cure mainly high fever agitation, twitch, dyspnea and cough due to lung-heat, heat knot renal shutdown, numbness pain limb fiber crops, hemiplegia and sore
The card such as pyogenic infections.Its drug ingedient is fast containing lumbricin, lumbrifebrine, terrestro-lumbrolysin, hypoxanthine, xanthine, adenine, bird
Purine, guanidine, choline, amino acid etc. have thrombolysis, anticoagulant, anti-arrhythmia and antitumor action.
The present invention selects Rhizoma Atractylodis Macrocephalae, rhizoma typhonii, bombyx batryticatus, scorpio, Radix Angelicae Sinensis, radix paeoniae rubra and pheretima, is to close yang-tonifying also five in Qianzheng San
It is added and subtracted on the square foundation of soup.Qianzheng San is the exogenous wind dispersing prescription in wind-curing prescription, white attached pungent, can control the wind of head；Silkworm, scorpion
It is salty, the broken knot of soft phlegm can be made, can wind in decomplexing；There is heat in pungent, three all controls the special medicine of wind, is taken after mixing with liquid with wine, with its warp of row, tool
There is the effect of dispelling pathogenic wind and eliminating phlegm, remove obstruction in channels to relieve pain, cures mainly the facial paralysis of obstruction of collateral caused by windphlegm.Buyang Huanwu Tang is blood-regulating prescription, has tonifying Qi,
The effect of promoting blood circulation, dredging collateral.Cure mainly the syndrome of blood stasis due to qi deficiency of apoplexy.Square radix angelicae sinensis is promoting blood circulation and removing obstruction in channels without blood trouble, and radix paeoniae rubra cooperates with radix angelicae sinensis
With promoting blood circulation, pheretima clearing and activating the channels and collaterals, power is specially apt to walk, all row whole bodies, with the row efficacy of a drug.Add with Rhizoma Atractylodis Macrocephalae simply, resolving sputum invigorating the spleen, spleen master
Transporting, The spleen and stomach provide the material basis of the acquired, and spleen and stomach function is normal, helps to run whole body qi and blood, qi and blood is logical, then channels and collaterals tune.Full Fang Yijing
Based on allusion quotation ancient prescription, make the prosperous blood of gas to effect a permanent cure, eliminating blood stasis and smoothing collaterals are to treat the symptoms, giving consideration to both the incidental and fundamental；And tonifying Qi is stagnant without stopping up, and invigorates blood circulation again not
Wound is just.It closes and uses it, then gas is prosperous, stagnation resolvation, network are logical, and all diseases are to being cured.
Embodiment 2:
A kind of seven taste face network leads to the preparation method of particle, and this method comprises the following steps:
S1: 12 grams of Rhizoma Atractylodis Macrocephalae, 6 grams of rhizoma typhonii, 9 grams of bombyx batryticatus, 3 grams of scorpio, 10 grams of Radix Angelicae Sinensis, 10 grams of radix paeoniae rubra and pheretima are weighed respectively
10 grams are pulverized into powder, and are mixed into powder；
S2: powder in step S1 is put into container, and the water of medicinal material total weight 600ml is added into container, container is set
The dregs of a decoction and filtrate one are obtained by filtration after 3 hours in boiling water bath；
S3: the obtained dregs of a decoction of step S2 are put into container, and the ethanol solution of 300ml95% is added into container to the dregs of a decoction
The dregs of a decoction are filtered off after impregnating 12 hours obtains filtrate two；
S4: it is added to the container and is mixed evenly after filtrate one and filtrate two are weighed, and is molten by the way that water or ethyl alcohol is added
The mass fraction that liquid adjusts ethyl alcohol in mixed solution is 65%, and extracting solution is obtained by filtration after mixed solution is stood 12 hours；
S5: heating extraction liquid is condensed into paste, and relative density is 1.25~1.30 when paste meets 60 DEG C；
S6: the paste in step S5 be granulated using spray drying process and drying forms particle；
S7: particle dry obtained in step S6 is subjected to package encapsulation with packaging bag.
In the present embodiment, Chinese medicine former material pulverizes into powder, is conducive to the dissolution of effective component in former material, and extraction rate is fast；Again
The dregs of a decoction after being decocted using alcohol solution dipping, extracting effective component, abundant, extraction recovery rate is high, solvent consumption is few；It passes through again
Granulating and drying is at particle after concentration, while remaining drug effect, is also convenient for packing and transport.
Step S2, the filter progress in S3 and S4 is filtered using negative pressure film filter.Negative pressure film filter packet
Include bottom belt orifice filter 1 crosses pan 2, crosses in pan 2 and is provided with filter membrane 3, and it is closed by being connected with communicating pipe 4 to cross pan 2
Filtrate collecting box 5, the top of filtrate collecting box 5 is connected with aspiration pump 7 by gas-guide tube 6, and 5 bottom of filtrate collecting box is provided with
Drain pipe 9 with valve 8.Because containing little particle Chinese medicine former material, when being filtered to mixed solution, filter membrane in mixed solution
3 were located at bottom in pan 2, and the filter hole on orifice filter 1 is blocked completely；Mixed solution is first incited somebody to action with distilled water before pouring into
Filter membrane 3 soaks, and can prevent the dregs of a decoction or sediment from flowing into filtrate collecting box 5 by filter membrane 3 and the gap crossed between pan 2；
After pouring into mixed solution, starting aspiration pump 7 is evacuated filtrate collecting box 5 by gas-guide tube 6, is less than the air pressure in collecting box outer
Boundary's atmospheric pressure, solvent and solute in mixed liquor are entered filtrate collecting box 5, the dregs of a decoction or heavy communicating pipe 4 after then passing through filter membrane 3
Starch matter is then delayed on filter membrane 3, is realized and is separated by solid-liquid separation.When needing to take out filtrate, the valve on drain pipe 9 need to be only opened
8 can be such that filtrate flows out.During the filtration process, because using negative pressure filtration, the rate of filtering is accelerated.
When extracting solution is concentrated in step S5, recycled using ethyl alcohol of the condenser pipe to evaporation, it can be by condensing recovery
Ethyl alcohol carries out dregs of a decoction soak extraction next time, and recycling economizes on resources.
Test example:
Analysis of cases: Zhao, male, people from Hefei City 20 years old, show themselves in that distortion of commissure, left eye dysraphism, Zuo Ewen disappear
It loses, nasolabial groove is shallow.After taking logical two courses for the treatment of of particle of seven taste face networks in the embodiment of the present invention 2, symptom mitigates, and continues to take this
After seven taste face networks of formula ratio lead to three courses for the treatment of of particle, symptom disappears substantially.
Analysis of cases: Mr. Wang, female, people from Hefei City 41 years old, show themselves in that the right eye dysraphism as caused by facial paralysis, right eyebrow lift
Difficulty is lifted, nasolabial groove shoals, drum mouth gas leakage, and after taking logical three courses for the treatment of of particle of seven taste face networks of the embodiment of the present invention 2, symptom subtracts
Gently, then take the formula ratio seven taste face networks lead to six courses for the treatment of of particle after, symptom disappears substantially.
Analysis of cases: Liu, male, people from Hefei City 62 years old, show themselves in that right side hypophasis, mouth as caused by facial paralysis
An angle left side is askew, and nasolabial groove shoals, and after taking logical three courses for the treatment of of particle of seven taste face networks of the embodiment of the present invention 2, symptom mitigates, then takes
After seven taste face networks of the formula ratio lead to seven courses for the treatment of of particle, symptom disappears substantially.
In addition, the clinical efficacy in order to further prove drug granule of the present invention, obtains 14 Peripheral Facial Paralysis Patients
Agree to, clinical observation is carried out to the curative effect of drug of the present invention.
Based on the judgement of curative effect is disappeared with symptom, and change situation with reference to effect etc., is divided into: effective, effective and invalid；
Effective: symptom is substantially reduced and effect is obviously improved.
Effective: symptom and effect have certain improvement.
Invalid: symptom and sign are unobvious without improvement or effect.
Using in drug therapy facial paralysis 14 of the present invention, male 9 female 5.Cardinal symptom are as follows: facial muscles inconvenient activity,
Saliva outflow, bicker are crooked outward, eyelid can not be closed, muffle deforms etc..There is symptom after oral drug therapy of the present invention
It is certain to improve, it can individually open, close one's eyes freely, both sides when laughing at of grinning are symmetrical；Wherein 9 effective (male 5, female 4), effective 14
Example, invalid 0, effective percentage 100%.
It as above is the embodiment of the present invention.Design parameter in above-described embodiment and embodiment is merely to understand table
Invention verification process is stated, the scope of patent protection being not intended to limit the invention, scope of patent protection of the invention is still with it
It is all to change with equivalent structure made by specification and accompanying drawing content of the invention subject to claims, it should all similarly wrap
Containing within the scope of the present invention.
Claims (5)
1. a kind of seven taste face networks lead to particle, which is characterized in that be mainly made by the Chinese medicine former material of following dry weight part: Rhizoma Atractylodis Macrocephalae 9~
15 parts, 6~14 parts of rhizoma typhonii, 8~14 parts of bombyx batryticatus, 3 parts of scorpio, 9~15 parts of Radix Angelicae Sinensis, 9~15 parts of radix paeoniae rubra and 9~15 parts of pheretima.
2. the preparation method that a kind of seven taste as described in claim 1 face network leads to particle, which comprises the steps of:
S1: by Chinese medicine former material 9~15 parts of Rhizoma Atractylodis Macrocephalae, 6~14 parts of rhizoma typhonii, 8~14 parts of bombyx batryticatus, 3 parts of scorpio, Radix Angelicae Sinensis 9 by weight
~15 parts, 9~15 parts of radix paeoniae rubra and 9~15 parts of pheretima pulverize into powder after weighing, and are mixed into powder；
S2: powder in step S1 is put into container, and 8~10 times of medicinal material total weight of water is added into container, container is placed in
The dregs of a decoction and filtrate one are obtained by filtration in boiling water bath after 2~3 hours；
S3: the obtained dregs of a decoction of step S2 are put into container, and into container, it is small to impregnate 12 to the dregs of a decoction for the ethanol solution of addition 95%
When after filter off the dregs of a decoction and obtain filtrate two, wherein the additional amount of ethanol solution is 5 times of step S1 Chinese medicine total amount；
S4: it is added to the container and is mixed evenly after filtrate one and filtrate two are weighed, and by the way that water or ethanol solution tune is added
The mass fraction of ethyl alcohol is 60~65% in whole mixed solution, and extracting solution is obtained by filtration after mixed solution is stood 12 hours；
S5: heating extraction liquid is condensed into paste；
S6: the paste in step S5 be granulated using spray drying process and drying forms particle；
S7: particle dry obtained in step S6 is subjected to package encapsulation with packaging bag.
3. the preparation method that seven taste according to claim 2 face network leads to particle, it is characterised in that: the cream in step S5
Relative density is 1.25~1.30 when shape object meets 60 DEG C.
4. the preparation method that seven taste according to claim 3 face network leads to particle, it is characterised in that: step S2, in S3 and S4
Filter progress be filtered using negative pressure film filter.
5. the preparation method that seven taste according to claim 3 face network leads to particle, it is characterised in that: extracting solution is dense in step S5
When contracting, recycled using ethyl alcohol of the condenser pipe to evaporation.
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