CN110038049A - A kind of plaster that treating rotavirus enteritis and preparation method - Google Patents

A kind of plaster that treating rotavirus enteritis and preparation method Download PDF

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Publication number
CN110038049A
CN110038049A CN201910420490.3A CN201910420490A CN110038049A CN 110038049 A CN110038049 A CN 110038049A CN 201910420490 A CN201910420490 A CN 201910420490A CN 110038049 A CN110038049 A CN 110038049A
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grams
oil
plaster
drug
medicine
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石如全
石红雨
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Mycology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of plaster for treating rotavirus enteritis, it contains following drug: smelly medicine, Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, Radix Glycyrrhizae, mantle, infantile malnutrition due to digestive disturbances or intestinalparasites grass, only angle gold, Canton love-pea vine, fructus polygoni orientalis, vegetable oil, yellow lead.The amount that the drug is specifically chosen: 95-110 grams of smelly medicine, 190-210 grams of Rhizoma Atractylodis Macrocephalae, 180-205 grams of Radix Codonopsis, 95-108 grams of Radix Glycyrrhizae, 95-104 grams of mantle, 46-52 grams of infantile malnutrition due to digestive disturbances or intestinalparasites grass, only 48-55 grams of gold, 46-54 grams of Canton love-pea vine, 240-255 grams of fructus polygoni orientalis of angle, 5300-5600 grams of vegetable oil, 2300-2480 grams of yellow lead.Using effect of the present invention is good, and the mode to be applied with, and is particularly suitable for child.

Description

A kind of plaster that treating rotavirus enteritis and preparation method
Technical field
The present invention relates to Chinese medicine, especially a kind of plaster for treating rotavirus enteritis and preparation method.
Background technique
Rotavirus enteritis is autumn relatively conventional disease, and morbidity range is wide, and Susceptible population is more, especially child, once Illness is such as not treated in time;It is easy to cause even more serious disease.Though in existing, Western medicine have the medicine used for children Object, but many childs directly take orally because the age is smaller or drink drug, it is more difficult, if be injected intravenously, children How dynamic and sensitive, there is also many inconvenience for specific treatment.
Summary of the invention
It is good that the object of the present invention is to provide a kind of therapeutic effects, and the plaster of the easy treatment rotavirus enteritis of application method and Preparation method.
The technical scheme is that a kind of plaster for treating rotavirus enteritis, it is characterised in that: it contains following drug: Smelly medicine, Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, Radix Glycyrrhizae, mantle, infantile malnutrition due to digestive disturbances or intestinalparasites grass, only angle gold, Canton love-pea vine, fructus polygoni orientalis, vegetable oil, yellow lead.
The amount that the drug is specifically chosen: 95-110 grams of smelly medicine, 190-210 grams of Rhizoma Atractylodis Macrocephalae, 180-205 grams of Radix Codonopsis, Radix Glycyrrhizae 95-108 grams, 95-104 grams of mantle, 46-52 grams of infantile malnutrition due to digestive disturbances or intestinalparasites grass, only 48-55 grams of angle gold, 46-54 grams of Canton love-pea vine, fructus polygoni orientalis 240-255 grams, 5300-5600 grams of vegetable oil, 2300-2480 grams of yellow lead.
Manufacture craft of the invention is a kind of preparation method for the plaster for treating rotavirus enteritis:
1, drug extract: will be ready to such as various drugs and plant oil it is other enter pot in impregnate two days two nights, then use small fire Heating, is stirred continuously with ash rod, until drug fries into withered yellow, removes the dregs of a decoction with the fishing of iron bamboo strainer;
2, refine oil: ripe refining is heated in medicine oil high fire, and ash rod is stirred continuously, and the hot Mao Qingyan of oil, then thicken cigarette, and oil is taken to instill in water Cheng Zhu does not dissipate, Guan Huo;
3, lower tool: leaving fire for oil cauldron, slowly lower pellet, and at the uniform velocity stirring but still is stirred to dropping into a bead until complete under red clockwise Afterwards, with tack-free, haircuts is pulled preferably;
4, releasing fire-toxin: and then the plaster being boiled into is poured into cooling in cold water, a cold water is changed daily, it can sharing ointment after 7 days.
Heating temperature in step 1 is 240-260 degree.
In the step 2: oil temperature reaches 310-330 degree.
Using effect of the present invention is good, and the mode to be applied with, and is particularly suitable for child.
Specific embodiment
Embodiment 1,
First choose: 95 grams of smelly medicine, 210 grams of Rhizoma Atractylodis Macrocephalae, 180 grams of Radix Codonopsis, 95 grams of Radix Glycyrrhizae, 104 grams of mantle, 46 grams of infantile malnutrition due to digestive disturbances or intestinalparasites grass, only angle 55 grams, 54 grams of Canton love-pea vine, 240 grams of fructus polygoni orientalis, 5300 grams of vegetable oil, 2300 grams of yellow lead of gold.
It is prepared again:
1, drug extract: will be ready to such as various drugs and plant oil it is other enter pot in impregnate two days two nights, then use small fire Heating, temperature is stirred continuously to 240 degree with ash rod, until drug fries into orange colour, is fished out with iron bamboo strainer and removes the dregs of a decoction;
2, refine oil: ripe refining is heated in medicine oil high fire, and ash rod is stirred continuously, and the hot Mao Qingyan of oil, oil temperature reaches 310 degree, then thickens Cigarette takes oil to instill Cheng Zhu in water and does not dissipate, Guan Huo;
3, lower tool: leaving fire for oil cauldron, slowly lower pellet, and at the uniform velocity stirring is complete under red clockwise.But still stirring is to dropping into a bead Afterwards, with tack-free, haircuts is pulled preferably.
4, releasing fire-toxin: and then the plaster being boiled into is poured into cooling in cold water, a cold water is changed daily, it can sharing medicine after 7 days Cream.
Embodiment 2
100 grams of smelly medicine, 200 grams of Rhizoma Atractylodis Macrocephalae, 200 grams of Radix Codonopsis, 100 grams of Radix Glycyrrhizae, 100 grams of mantle, 50 grams of infantile malnutrition due to digestive disturbances or intestinalparasites grass, only angle gold 50 Gram, 50 grams of Canton love-pea vine, 250 grams of fructus polygoni orientalis, 5500 grams of vegetable oil, 2400 grams of yellow lead.
It is prepared again:
1, drug extract: will be ready to such as various drugs and plant oil it is other enter pot in impregnate two days two nights, then use small fire Heating, temperature is stirred continuously to 260 degree with ash rod, until drug fries into orange colour, is fished out with iron bamboo strainer and removes the dregs of a decoction;
2, refine oil: ripe refining is heated in medicine oil high fire, and ash rod is stirred continuously, and the hot Mao Qingyan of oil, oil temperature reaches 320 degree, then thickens Cigarette takes oil to instill Cheng Zhu in water and does not dissipate, Guan Huo;
3, lower tool: leaving fire for oil cauldron, slowly lower pellet, and at the uniform velocity stirring is complete under red clockwise.But still stirring is to dropping into a bead Afterwards, with tack-free, haircuts is pulled preferably.
4, releasing fire-toxin: and then the plaster being boiled into is poured into cooling in cold water, a cold water is changed daily, it can sharing medicine after 7 days Cream.
Embodiment 3
First choose: 110 grams of smelly medicine, 210 grams of Rhizoma Atractylodis Macrocephalae, 205 grams of Radix Codonopsis, 108 grams of Radix Glycyrrhizae, 95 grams of mantle, 52 grams of infantile malnutrition due to digestive disturbances or intestinalparasites grass, only angle 48 grams, 46 grams of Canton love-pea vine, 255 grams of fructus polygoni orientalis, 5600 grams of vegetable oil, 2480 grams of yellow lead of gold.
It is prepared again:
1, drug extract: will be ready to such as various drugs and plant oil it is other enter pot in impregnate two days two nights, then use small fire Heating, temperature is stirred continuously to 250 degree with ash rod, until drug fries into orange colour, is fished out with iron bamboo strainer and removes the dregs of a decoction;
2, refine oil: ripe refining is heated in medicine oil high fire, and ash rod is stirred continuously, and the hot Mao Qingyan of oil, oil temperature reaches 330 degree, then thickens Cigarette takes oil to instill Cheng Zhu in water and does not dissipate, Guan Huo;
3, lower tool: leaving fire for oil cauldron, slowly lower pellet, and at the uniform velocity stirring is complete under red clockwise.But still stirring is to dropping into a bead Afterwards, with tack-free, haircuts is pulled preferably.
4, releasing fire-toxin: and then the plaster being boiled into is poured into cooling in cold water, a cold water is changed daily, it can sharing medicine after 7 days Cream.
Application method of the present invention:
1. booth cream: the plaster after releasing fire-toxin being put into iron pan and is dissolved, takes the plaster of 2.5g-4g to be spread out in medicated plaster cloth with a bamboo chopsticks On be affixed on navel, separately take 5g-7g plaster to be affixed on MINGMEN acupoint, often forcing on two days, it is primary to change.
2. taboo: fasting is raw and cold, greasy, pungent, seafood group food.
3. points for attention: plaster is itched and is taken off after patch, pastes again after not itching, and allergic skin or skin have the rotten place of something lost to forbid It sticks.
The above embodiments are merely examples for clarifying the description, and does not limit the embodiments.For institute For the those of ordinary skill in category field, other various forms of variations or change can also be made on the basis of the above description It is dynamic.There is no necessity and possibility to exhaust all the enbodiments, and obvious variation extended from this or change It moves within still in the protection scope of the invention.
Case:
1, Shi, male, one-year-old two months, people from village, Shilou County, August in 2018 8 was examined, main suit: baby's diarrhea two days, one day six Secondary, egg soup sample of defecating, test excrement, rotavirus, after developing weighing apparatus taste patch, times of defecation is reduced within second day, third day egg Flower soup sample stool is reduced, and No. 13 further consultation stool of August are normal, and multiple note consolidates curative effect.
2, a Ji so-and-so, male, three months, live Fengqiu County than street primary school, carry out further consultation on July 26th, 2018, main suit: baby's abdomen It rushes down three days, one day 8-10 times, lassitude is taken medicine ineffective with low fever, test excrement, rotavirus.Develop weighing apparatus taste patch Further consultation two days later, diarrhea number significantly reduce, and stool matter is thick.No. 1 further consultation of August, recovery from illness, multiple note consolidate curative effect.
3, Mr. Li, female, one-year-old half, people from the village An Xia, Yanjin County, September in 2018 5 days is examined, main suit: baby's diarrhea one week, The light not smelly of thin color that defecates of looking wane and sallow eats and rushes down, and receives difference, lassitude test excrement: rotavirus, oral medicine and in Drug paste is invalid.Weighing apparatus taste patch, No. 8 further consultations stool retrogradation are developed, number is reduced, and 2 days convulsions are cured after multiple patch.
4, Mr. Wang, female, 8 months 2 years old, Fengqiu County area just outside a city gate township people from the village Er Langmiao, in January, 2018 No. 2 medical, main suits: child Son causes egg flower sample diarrhea because eating cold drink, matter is dilute, often, abdominal pain, vomiting develops weighing apparatus taste patch, and parent sends a telegram here and says after three days It defecates molded, once a day, No. 6 multiple patches are fully recovered after 2 days.
5, Mr. Li, male 11 months, the Fengqiu County township Chen Gu people from the village Li Matai, on January 5th, 2018 medical, diarrhea fever 1 It, 38 degree of highest, come 37.5 degree when examining, fingerprint is red, red tongue and white coating on the tongue stool egg soup sample, and for several times, develops weighing apparatus taste and paste, second Its burning is moved back, and stool matter pin is thick, further consultation in the 4th day, and defecate retrogradation, turns yellow, and egg flower just disappears, and is fully recovered after multiple patch.

Claims (5)

1. a kind of plaster for treating rotavirus enteritis, it is characterised in that: it contains following drug: smelly medicine, Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, Radix Glycyrrhizae, one Mouth clock, infantile malnutrition due to digestive disturbances or intestinalparasites grass, only angle gold, Canton love-pea vine, fructus polygoni orientalis, vegetable oil, yellow lead.
2. a kind of plaster for treating rotavirus enteritis as described in claim 1, which is characterized in that the drug was specifically chosen Amount: 95-110 grams of smelly medicine, 190-210 grams of Rhizoma Atractylodis Macrocephalae, 180-205 grams of Radix Codonopsis, 95-108 grams of Radix Glycyrrhizae, 95-104 grams of mantle, infantile malnutrition due to digestive disturbances or intestinalparasites It is careless 46-52 grams, only 48-55 grams of angle gold, 46-54 grams of Canton love-pea vine, 240-255 grams of fructus polygoni orientalis, 5300-5600 grams of vegetable oil, yellow Red 2300-2480 grams.
3. a kind of preparation method for the plaster for treating rotavirus enteritis: it is characterized by:
(1), drug extract: will be ready to such as various drugs and plant oil it is other enter pot in impregnate two days two nights, then with small Fire heating, is stirred continuously with ash rod, until drug fries into withered yellow, removes the dregs of a decoction with the fishing of iron bamboo strainer;
(2), refine oil: ripe refining is heated in medicine oil high fire, and ash rod is stirred continuously, and the hot Mao Qingyan of oil, then thicken cigarette, and oil is taken to instill water Middle Cheng Zhu does not dissipate, Guan Huo;
(3), lower tool: leaving fire for oil cauldron, slowly lower pellet, and at the uniform velocity stirring but still is stirred to dripping into until complete under red clockwise After pearl, with tack-free, haircuts is pulled preferably;
(4), releasing fire-toxin: and then the plaster being boiled into is poured into cooling in cold water, a cold water is changed daily, it can sharing ointment after 7 days.
4. a kind of preparation method of plaster for treating rotavirus enteritis as claimed in claim 3, which is characterized in that the step Heating temperature in 1 is 240-260 degree.
5. a kind of preparation method of plaster for treating rotavirus enteritis as claimed in claim 3, which is characterized in that described the In 2 steps: oil temperature reaches 310-330 degree.
CN201910420490.3A 2019-05-20 2019-05-20 A kind of plaster that treating rotavirus enteritis and preparation method Pending CN110038049A (en)

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Application Number Priority Date Filing Date Title
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1824270A (en) * 2005-12-15 2006-08-30 北京阜康仁生物制药科技有限公司 Middle-jiao regulating medicinal preparation and its new preparation method
CN107595893A (en) * 2017-08-25 2018-01-19 广西中医药大学 A kind of enzyme treated prepared slices of Chinese crude drugs and preparation method thereof
CN108524594A (en) * 2018-04-03 2018-09-14 何洁 Invigorating the spleen herbal medicine tea composition, invigorating the spleen herbal medicine tea formulation and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1824270A (en) * 2005-12-15 2006-08-30 北京阜康仁生物制药科技有限公司 Middle-jiao regulating medicinal preparation and its new preparation method
CN107595893A (en) * 2017-08-25 2018-01-19 广西中医药大学 A kind of enzyme treated prepared slices of Chinese crude drugs and preparation method thereof
CN108524594A (en) * 2018-04-03 2018-09-14 何洁 Invigorating the spleen herbal medicine tea composition, invigorating the spleen herbal medicine tea formulation and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘俊仕: "《中医方剂快速记忆法》", 31 May 2000, 人民军医出版社 *
张奇文: "《中国膏敷疗法 第2版》", 31 January 2018, 中国医药科技出版社 *

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Application publication date: 20190723

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