CN110037854B - Glaucoma aqueous humor drainage device - Google Patents
Glaucoma aqueous humor drainage device Download PDFInfo
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- CN110037854B CN110037854B CN201910247100.7A CN201910247100A CN110037854B CN 110037854 B CN110037854 B CN 110037854B CN 201910247100 A CN201910247100 A CN 201910247100A CN 110037854 B CN110037854 B CN 110037854B
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- aqueous humor
- glaucoma
- drainage
- drainage catheter
- drainage device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
Abstract
The utility model provides a glaucoma aqueous humor drainage device and glaucoma aqueous humor drainage method, the switch of the intracavity pressure control valve through the cavity in the pressure valve, when intraocular pressure's pressure exceeded 12mmHg, the valve was opened, and it drains to the ocular surface to connect the drainage tube behind the valve with the aqueous humor to and alleviate patient's uncomfortable sense and dry eye, can effectively drain the aqueous humor, thereby avoid arousing the cicatrization and filter the production of bubble through conjunctiva valve embedding device and lead to the fact the operation failure that the intraocular pressure risees.
Description
Technical Field
The invention particularly relates to the technical field of ophthalmology, and particularly relates to a glaucoma aqueous humor drainage device and a glaucoma aqueous humor drainage method.
Background
Glaucoma is the second leading cause of blindness in the world and is a group of optic neuropathy diseases characterized by alterations in optic nerve head structure and resulting in visual field defects and ultimately blindness. By 2020, approximately 7960 million people worldwide have glaucoma, and over 1100 million people will have glaucoma on both eyes. Lowering intraocular pressure is the only method proven scientifically effective to delay the progression of glaucoma. Lowering intraocular pressure in glaucoma patients can be achieved by drug, laser, and surgical treatment. The anti-glaucoma surgery which is generally applied clinically at present: trabeculectomy, simple cataract surgery, combined glaucoma operation and ciliary photocoagulation. Trabeculectomy is the conventional classic surgical procedure for glaucoma, with its complications still unavoidable, low intraocular pressure, 20-40% of the superficial anterior chamber, choroidal detachment 2%, and cystoid macular edema 1% in the early stages. Surgery failure may occur at the late stage, and the scarring problem of the bleb increases with time, reaching 50% in about 5 years. Complications with blebs include bleb leakage, infection, drooping, and the effect of blebs on ocular surface structure and function. The glaucoma difficult to treat in glaucoma includes glaucoma secondary to iridocorneal endothelial syndrome, glaucoma secondary to trauma, glaucoma secondary to inflammation, glaucoma which has failed in previous filtering surgery, and the like. This type of glaucoma is characterized by difficulty in controlling intraocular pressure using conventional means, and by failure of the procedure after conventional trabeculectomy due to the tendency of the filtering bleb to scar. In recent years, glaucoma aqueous humor drainage valve surgery is gradually popularized, and compared with the traditional trabeculectomy, the surgery mode has obvious high success rate of treating refractory glaucoma. It is through making the conjunctiva valve with drainage dish embedding under the conjunctiva, also consequently cause the fibrous tissue hyperplasia around the drainage dish to then scar and parcel bubble form around the drainage dish and lead to the unable diffusion of aqueous humor to lead to the intraocular pressure to rise once more, cause the operation failure.
Disclosure of Invention
In order to solve the technical defects in the prior art, the invention provides a glaucoma aqueous humor drainage device and a glaucoma aqueous humor drainage method, which can effectively drain aqueous humor and avoid scar formation caused by a conjunctival flap embedding device and operation failure caused by increased intraocular pressure due to generation of a filtering bulb.
The technical solution adopted by the invention is as follows: a glaucoma aqueous humor drainage device comprises a device body, wherein the device body comprises a pressure valve, and an inner drainage catheter for draining aqueous humor of an anterior chamber into a cavity in the pressure valve and an outer drainage catheter for draining aqueous humor of the anterior chamber into an ocular surface after the pressure valve reaches a threshold value are connected onto the pressure valve.
The pressure threshold of the pressure valve is 12 mmHg.
Two ends of the outer drainage catheter are respectively connected to a cavity in the pressure valve to form an annular closed structure.
The wall of the outer drainage catheter is provided with a plurality of through holes, and aqueous humor of the anterior chamber is drained to the ocular surface through the through holes on the wall of the outer drainage catheter.
The inner pipe wall of the outer drainage catheter is also covered with a semipermeable membrane material.
The through holes are sequentially distributed at the 3 o 'clock positions, the 6 o' clock positions, the 9 o 'clock positions and the 12 o' clock positions of the annular closed structure formed by the outer drainage catheter in a clock pointer mode.
The through hole is a circular pore canal with the aperture of 500 mu m.
The inner diameter of the inner drainage catheter is 1mm, and the length of the inner drainage catheter is 8 mm.
The diameter of the annular closed structure formed by the outer drainage catheter is less than 30 mm.
The inner drainage catheter and the outer drainage catheter are both made of biocompatible materials.
The wall of the external drainage catheter is made of a semipermeable membrane material.
The ultrafiltration molecular weight of the semipermeable membrane material is 500-500000D, and the pore size is 1nm-1 μm.
The external drainage catheter (3) is also provided with a lead wire for fixing the external drainage catheter (3) by tension.
A method of glaucoma aqueous humor drainage comprising the steps of: the inner drainage catheter of the drainage device is submerged under a superficial scleral flap 3-4mm away from the limbus of the cornea, the inner drainage catheter is rotated to form an included angle of 5-10 degrees with the iris to puncture into the anterior chamber after reaching the limbus, the inner drainage catheter is fixed on the superficial scleral surface by an absorbable thread after being inserted into the anterior chamber, the pressure valve is placed along the radian of the sclera, the eyelid is propped open, and the outer drainage catheter is placed along the radian of the sclera and fixed under the conjunctiva of the fornix.
The external drainage catheter is positioned between the fornix conjunctiva and the corneal limbus and is 8-10mm away from the fornix conjunctiva and the upper part and the lower part of the corneal limbus.
The invention has the beneficial effects that: the invention provides a glaucoma aqueous humor drainage device and a glaucoma aqueous humor drainage method, wherein the opening and closing of a valve are controlled through the change of the intracavity pressure of a cavity in a pressure valve, when the pressure of intraocular pressure exceeds 10mmHg, the valve is opened, a drainage tube is connected behind the valve to drain aqueous humor to the ocular surface, the discomfort and the eye dryness of a patient are relieved, the aqueous humor can be effectively drained, and the operation failure caused by the cicatrization caused by a conjunctival flap embedding device and the increase of intraocular pressure caused by the generation of filtering bubbles is avoided.
Drawings
FIG. 1 is a schematic view of the structure of the apparatus of the present invention.
FIG. 2 is another schematic diagram of the present invention.
Wherein, 1-pressure valve, 2-internal drainage catheter, 3-external drainage catheter and 4-through hole.
Detailed Description
The invention is further explained by combining fig. 1 and fig. 2, and the glaucoma aqueous humor drainage device comprises a device body, wherein the device body comprises a pressure valve 1, an inner drainage catheter 2 for draining aqueous humor of the anterior chamber into a cavity in the pressure valve 1 and an outer drainage catheter 3 for draining aqueous humor of the anterior chamber in the cavity of the pressure valve 1 to the surface of the eye after the pressure valve 1 reaches a threshold value are connected to the pressure valve 1. The inner diameter of the inner drainage catheter 2 is 1mm, and the length is 8 mm.
The pressure valve is of a flat structure, is attached to the temporal sclera through a surface radian, avoids discomfort, and controls the opening and closing of the valve through the change of the pressure in the cavity.
The pressure threshold of the pressure valve 1 is 12 mmHg. When the pressure of the intraocular pressure exceeds 12mmHg, the valve is opened, a drainage tube is connected behind the valve to drain the aqueous humor to the ocular surface, the discomfort and the eye dryness of a patient are relieved, and the aqueous humor can be effectively drained
Two ends of the outer drainage catheter 3 are respectively connected to the left end and the right end of the cavity in the pressure valve 1 to form an annular closed structure. The diameter of the annular closed structure formed by the outer drainage catheter 3 is less than 30 mm.
The wall of the outer drainage catheter 3 is provided with a plurality of through holes 4, and aqueous humor in the anterior chamber is drained to the ocular surface through the through holes 4 on the wall of the outer drainage catheter 3. The through holes 4 are sequentially distributed at the 3 o 'clock positions, 6 o' clock positions, 9 o 'clock positions and 12 o' clock positions of the annular closed structure formed by the outer drainage catheter 3 according to the clock pointer mode. The through hole 4 is a circular pore canal with the aperture of 500 mu m.
The inner pipe wall of the external drainage catheter 3 is also covered with a semipermeable membrane material or the pipe wall of the external drainage catheter 3 is made of a semipermeable membrane material. The ultrafiltration molecular weight of the semipermeable membrane material is 500-500000D, and the pore size is 1nm-1 μm.
The inner drainage catheter 2 and the outer drainage catheter 3 are both made of biocompatible materials.
The outer drainage catheter 3 is also provided with a lead wire for fixing the outer drainage catheter (3) by tension.
The other structure of the glaucoma aqueous humor drainage device is shown in fig. 2, wherein the tube wall of the outer drainage catheter 3 is made of a semipermeable membrane material, and the drainage quantity of the annular inner drainage catheter 2 made of the semipermeable membrane material of the aqueous humor eye surface drainage device is 3.6ml/d and the required filtration area is 80um2 because the production rate of aqueous humor of a normal person is 2.88-4.32 ml/day. No additional tubular structure is required. The ultrafiltration molecular weight of the semipermeable membrane material is 500-500000D, and the pore size is 1nm-1 μm.
A method of glaucoma aqueous humor drainage comprising the steps of: the patient takes a supine position, after surface anesthesia, a conventional disinfection drape is adopted, after an eye is operated, iodophor solution is diluted to wash a conjunctival sac, an inner drainage catheter of a drainage device is submerged under a shallow scleral flap 3-4mm away from the limbus, the inner drainage catheter is turned into an included angle of 5-10 degrees with an iris after reaching the limbus and then is punctured into an anterior chamber, after the inner drainage catheter is inserted into the anterior chamber, the inner drainage catheter is fixed on the shallow scleral surface by using 8-0 absorbable thread, a pressure valve is arranged along the radian of sclera, the eyelid is opened, an outer drainage catheter is arranged along the radian of the sclera and is fixed under the fornix conjunctiva, and the eye is coated with tobrambutan dexamethasone eye ointment after the operation is finished. The position of the external drainage catheter is positioned between the fornix conjunctiva and the corneal limbus and is 8-10mm away from the fornix conjunctiva and the upper and lower parts of the corneal limbus.
In the description of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art. In addition, in the description of the present invention, "a plurality" means two or more unless otherwise specified.
The skilled person should understand that: although the invention has been described in terms of the above specific embodiments, the inventive concept is not limited thereto and any modification applying the inventive concept is intended to be included within the scope of the patent claims.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.
Claims (12)
1. The glaucoma aqueous humor drainage device comprises a device body and is characterized in that the device body comprises a pressure valve (1), an inner drainage conduit (2) for draining aqueous humor of the anterior chamber into a cavity in the pressure valve (1) and an outer drainage conduit (3) for draining aqueous humor of the anterior chamber in the cavity of the pressure valve (1) to an eye surface after the pressure valve (1) reaches a threshold value are connected to the pressure valve (1), and two ends of the outer drainage conduit (3) are respectively connected to the cavity in the pressure valve (1) to form an annular closed structure.
2. The glaucomatous aqueous humor drainage device of claim 1, wherein the pressure threshold of the pressure valve (1) is 12 mmHg.
3. The glaucoma aqueous humor drainage device according to claim 1, wherein a plurality of through holes (4) are formed on the wall of the outer drainage catheter (3), and the aqueous humor in the anterior chamber is drained to the ocular surface through the through holes (4) on the wall of the outer drainage catheter (3).
4. The glaucoma aqueous humor drainage device of claim 1, wherein the wall of the outer drainage catheter (3) is made of a semi-permeable membrane material.
5. The glaucoma aqueous humor drainage device of claim 3, wherein the inner tube wall of the outer drainage catheter (3) is further covered with a semipermeable membrane material.
6. The glaucoma drainage device according to claim 3 wherein the through holes (4) are arranged in a clock hand manner in the 3, 6, 9, 12 o' clock positions of the annular closed structure formed by the outer drainage catheter (3).
7. The glaucoma drainage device according to claim 3 wherein the through-hole (4) is a circular hole with a diameter of 500 μm.
8. The glaucoma aqueous humor drainage device of claim 1, wherein the inner drainage catheter (2) has an inner diameter of 1mm and a length of 8 mm.
9. A glaucoma drainage device according to claim 1 where the outer drainage catheter (3) forms an annular enclosure of less than 30mm diameter.
10. The glaucoma aqueous humor drainage device of claim 1, wherein the inner drainage catheter (2) and the outer drainage catheter (3) are made of biocompatible materials.
11. The glaucoma aqueous humor drainage device of claim 4 or 5, wherein the semipermeable membrane material has an ultrafiltration molecular weight of 500-500000D and a pore size of 1nm-1 μm.
12. The glaucomatous aqueous humor drainage device according to claim 1, wherein the outer drainage catheter (3) is further provided with a lead wire for fixing the outer drainage catheter (3) by tension.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910247100.7A CN110037854B (en) | 2019-03-29 | 2019-03-29 | Glaucoma aqueous humor drainage device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910247100.7A CN110037854B (en) | 2019-03-29 | 2019-03-29 | Glaucoma aqueous humor drainage device |
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| CN110037854A CN110037854A (en) | 2019-07-23 |
| CN110037854B true CN110037854B (en) | 2021-04-20 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113081474B (en) * | 2021-03-31 | 2023-03-10 | 武汉爱尔眼科医院有限公司 | Adjustable aqueous humor drainage device for glaucoma eyes and use method |
| CN114369532B (en) * | 2021-12-31 | 2023-10-03 | 中国科学院苏州纳米技术与纳米仿生研究所 | Microfluidic cell culture device simulating filtration bleb and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1748661A (en) * | 2005-10-17 | 2006-03-22 | 西安交通大学 | Novel aqueous humor drainage device for glaucoma |
| CN103190983A (en) * | 2012-01-05 | 2013-07-10 | 首都医科大学 | Aqueous humor drainage implant |
| CN204319045U (en) * | 2014-12-01 | 2015-05-13 | 复旦大学附属眼耳鼻喉科医院 | A kind of aqueous humor drainage device for glaucoma |
| US20160067092A1 (en) * | 2014-09-10 | 2016-03-10 | Novartis Ag | Intraocular pressure sensing system for posterior segment drainage |
| CN109223302A (en) * | 2018-11-21 | 2019-01-18 | 中国人民解放军总医院 | A kind of aqueous humor drainage device and manufacturing method |
-
2019
- 2019-03-29 CN CN201910247100.7A patent/CN110037854B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1748661A (en) * | 2005-10-17 | 2006-03-22 | 西安交通大学 | Novel aqueous humor drainage device for glaucoma |
| CN103190983A (en) * | 2012-01-05 | 2013-07-10 | 首都医科大学 | Aqueous humor drainage implant |
| US20160067092A1 (en) * | 2014-09-10 | 2016-03-10 | Novartis Ag | Intraocular pressure sensing system for posterior segment drainage |
| CN204319045U (en) * | 2014-12-01 | 2015-05-13 | 复旦大学附属眼耳鼻喉科医院 | A kind of aqueous humor drainage device for glaucoma |
| CN109223302A (en) * | 2018-11-21 | 2019-01-18 | 中国人民解放军总医院 | A kind of aqueous humor drainage device and manufacturing method |
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| CN110037854A (en) | 2019-07-23 |
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Effective date of registration: 20211130 Address after: 325013 room 220, building a, No. 100, Luodong North Street, Yongzhong street, Longwan District, Wenzhou City, Zhejiang Province Patentee after: Wenzhou Xiaoliang Medical Technology Co.,Ltd. Address before: 325000 No. 270 College West Road, Zhejiang, Wenzhou Patentee before: THE EYE HOSPITAL OF WENZHOU MEDICAL University |