CN110023512A - 用于预测乳腺癌患者的化疗有效性的方法 - Google Patents

用于预测乳腺癌患者的化疗有效性的方法 Download PDF

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Publication number
CN110023512A
CN110023512A CN201780072701.8A CN201780072701A CN110023512A CN 110023512 A CN110023512 A CN 110023512A CN 201780072701 A CN201780072701 A CN 201780072701A CN 110023512 A CN110023512 A CN 110023512A
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China
Prior art keywords
breast cancer
chemotherapy
gene
expression
predicting
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Pending
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CN201780072701.8A
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English (en)
Chinese (zh)
Inventor
赵相来
文永镐
韩振日
慎英基
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Gencurix Inc
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Gencurix Inc
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Priority to CN202310347279.XA priority Critical patent/CN116377075A/zh
Publication of CN110023512A publication Critical patent/CN110023512A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201780072701.8A 2016-11-23 2017-11-23 用于预测乳腺癌患者的化疗有效性的方法 Pending CN110023512A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310347279.XA CN116377075A (zh) 2016-11-23 2017-11-23 用于预测乳腺癌患者的化疗有效性的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020160156824A KR101950717B1 (ko) 2016-11-23 2016-11-23 유방암 환자의 화학치료 유용성 예측 방법
KR10-2016-0156824 2016-11-23
PCT/KR2017/013404 WO2018097614A2 (ko) 2016-11-23 2017-11-23 유방암 환자의 화학치료 유용성 예측 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202310347279.XA Division CN116377075A (zh) 2016-11-23 2017-11-23 用于预测乳腺癌患者的化疗有效性的方法

Publications (1)

Publication Number Publication Date
CN110023512A true CN110023512A (zh) 2019-07-16

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CN201780072701.8A Pending CN110023512A (zh) 2016-11-23 2017-11-23 用于预测乳腺癌患者的化疗有效性的方法
CN202310347279.XA Pending CN116377075A (zh) 2016-11-23 2017-11-23 用于预测乳腺癌患者的化疗有效性的方法

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Country Link
US (1) US10718030B2 (cg-RX-API-DMAC7.html)
EP (1) EP3524690B1 (cg-RX-API-DMAC7.html)
JP (2) JP2019535286A (cg-RX-API-DMAC7.html)
KR (1) KR101950717B1 (cg-RX-API-DMAC7.html)
CN (2) CN110023512A (cg-RX-API-DMAC7.html)
ES (1) ES2963390T3 (cg-RX-API-DMAC7.html)
WO (1) WO2018097614A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111118146A (zh) * 2020-02-10 2020-05-08 山东大学齐鲁医院(青岛) LncRNA在乳腺癌化疗相关心肌损伤患者诊断中的应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101950717B1 (ko) * 2016-11-23 2019-02-21 주식회사 젠큐릭스 유방암 환자의 화학치료 유용성 예측 방법
KR102221206B1 (ko) * 2019-03-08 2021-03-02 서울대학교산학협력단 유방암 샘플에서 질량분석법 의한 her2 정량 방법 및 이를 이용한 her2 상태 스코어링
US20220221460A1 (en) * 2019-03-08 2022-07-14 Seoul National University R&Db Foundation Method of quantifying her2 in breast cancer sample by mass spectrometry and scoring her2 status using the same
KR102490338B1 (ko) * 2020-03-24 2023-01-19 (의료)길의료재단 질병의 치료 및 예방을 위한 신약 타겟 유전자 예측 방법
KR102422610B1 (ko) * 2020-05-12 2022-07-18 서울대학교 산학협력단 초기 유방암 환자의 예후 예측 방법
WO2023164653A1 (en) * 2022-02-25 2023-08-31 The Regents Of The University Of California Breast cancer-response prediction subtypes
JP7446376B1 (ja) 2022-09-06 2024-03-08 株式会社キャタラー パティキュレートフィルタ

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160102359A1 (en) * 2013-04-18 2016-04-14 Gencurix Inc. Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7081340B2 (en) * 2002-03-13 2006-07-25 Genomic Health, Inc. Gene expression profiling in biopsied tumor tissues
US20070172844A1 (en) * 2005-09-28 2007-07-26 University Of South Florida Individualized cancer treatments
WO2007070621A2 (en) * 2005-12-13 2007-06-21 Children's Medical Center Corporation Prognosis indicators for solid human tumors
EP3135773A1 (en) * 2006-09-27 2017-03-01 Sividon Diagnostics GmbH Methods for breast cancer prognosis
ES2338843B1 (es) * 2008-07-02 2011-01-24 Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas Huella genomica de cancer de mama.
KR101421326B1 (ko) * 2010-03-30 2014-07-21 서울대학교산학협력단 유방암 예후 예측을 위한 조성물 및 이를 포함하는 키트
EP2553118B1 (en) * 2010-03-31 2014-10-15 Sividon Diagnostics GmbH Method for breast cancer recurrence prediction under endocrine treatment
KR101287600B1 (ko) * 2011-01-04 2013-07-18 주식회사 젠큐릭스 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법
WO2013071247A1 (en) * 2011-11-10 2013-05-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Gene expression signatures of neoplasm responsiveness to theraphy
CA2874492C (en) * 2012-05-22 2021-10-19 British Columbia Cancer Agency Branch Nano46 genes and methods to predict breast cancer outcome
KR101725985B1 (ko) * 2013-01-28 2017-04-13 주식회사 젠큐릭스 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법
KR101748867B1 (ko) 2013-04-19 2017-06-20 주식회사 젠큐릭스 조기 유방암 예후 예측 진단용 자동화 시스템
KR101632628B1 (ko) * 2014-03-31 2016-06-23 제이더블유중외제약 주식회사 유방암 재발 또는 전이 억제용 제제의 스크리닝 방법
US10174382B2 (en) * 2015-05-13 2019-01-08 University Of Notre Dame Breast cancer prognostication and screening kits and methods of using same
KR101950717B1 (ko) * 2016-11-23 2019-02-21 주식회사 젠큐릭스 유방암 환자의 화학치료 유용성 예측 방법
KR101896545B1 (ko) * 2016-11-25 2018-09-07 주식회사 젠큐릭스 유방암 환자의 예후 예측 방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160102359A1 (en) * 2013-04-18 2016-04-14 Gencurix Inc. Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MARIE KLINTMAN: "Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease", 《CLIN CANCER RES》 *
MI JEONG KWON: "Identification of Novel Reference Genes UsingMultiplatform Expression Data and Their Validation for Quantitative Gene Expression Analysis", 《PLOS ONE》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111118146A (zh) * 2020-02-10 2020-05-08 山东大学齐鲁医院(青岛) LncRNA在乳腺癌化疗相关心肌损伤患者诊断中的应用

Also Published As

Publication number Publication date
JP2022141708A (ja) 2022-09-29
WO2018097614A3 (ko) 2018-08-09
KR101950717B1 (ko) 2019-02-21
JP7430415B2 (ja) 2024-02-13
JP2019535286A (ja) 2019-12-12
WO2018097614A2 (ko) 2018-05-31
EP3524690B1 (en) 2023-08-30
ES2963390T3 (es) 2024-03-26
KR20180058118A (ko) 2018-05-31
US10718030B2 (en) 2020-07-21
EP3524690C0 (en) 2023-08-30
CN116377075A (zh) 2023-07-04
EP3524690A2 (en) 2019-08-14
US20180216198A1 (en) 2018-08-02
EP3524690A4 (en) 2020-06-17

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Application publication date: 20190716

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