CN110023486A - 一种嗜酸乳杆菌及其培养方法和应用 - Google Patents

一种嗜酸乳杆菌及其培养方法和应用 Download PDF

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CN110023486A
CN110023486A CN201680091076.7A CN201680091076A CN110023486A CN 110023486 A CN110023486 A CN 110023486A CN 201680091076 A CN201680091076 A CN 201680091076A CN 110023486 A CN110023486 A CN 110023486A
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lactobacillus acidophilus
pharmaceutical composition
application
acid
cfu
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CN110023486B (zh
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邹远强
薛文斌
肖亮
李晓平
余靖宏
刘传
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BGI Shenzhen Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/127—Fermented milk preparations; Treatment using microorganisms or enzymes using microorganisms of the genus lactobacteriaceae and other microorganisms or enzymes, e.g. kefir, koumiss
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C12R2001/23—Lactobacillus acidophilus

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

提供一种嗜酸乳杆菌及其培养方法和应用，该嗜酸乳杆菌（Lactobacillus acidophilus）AM13‑1，保藏于广东省微生物菌种保藏中心，其保藏编号为GDMCC 60091。嗜酸乳杆菌AM13‑1可以有效的降胆固醇，对溃疡性肠炎有明显的缓解作用。

Description

PCT国内申请，说明书已公开。

Claims (15)

  1. PCT国内申请，权利要求书已公开。
CN201680091076.7A 2016-12-20 2016-12-20 一种嗜酸乳杆菌及其培养方法和应用 Active CN110023486B (zh)

Applications Claiming Priority (1)

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PCT/CN2016/111028 WO2018112741A1 (zh) 2016-12-20 2016-12-20 一种嗜酸乳杆菌及其培养方法和应用

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CN110023486B CN110023486B (zh) 2022-02-22

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114231470A (zh) * 2022-01-26 2022-03-25 江南大学 一株可缓解溃疡性结肠炎的嗜酸乳杆菌及其应用
CN114574543A (zh) * 2022-04-12 2022-06-03 广西南宁佰奥吉生物科技有限公司 一种耐高温的乳酸菌选育方法
CN114672436A (zh) * 2022-04-07 2022-06-28 重庆医科大学 一株嗜酸乳杆菌及其应用
CN117305188A (zh) * 2023-11-27 2023-12-29 山东中微众康生物科技有限公司 促进儿童骨生长的嗜酸乳杆菌RZKLa0701及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113755370B (zh) * 2021-08-23 2023-11-14 微康益生菌(苏州)股份有限公司 嗜酸乳杆菌la85在制备降血脂药物或保健食品上的应用

Citations (5)

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CN104928206A (zh) * 2015-04-29 2015-09-23 东北农业大学 一株具有高胆酸盐水解酶活性的嗜酸乳杆菌及其应用
CN105343132A (zh) * 2015-12-08 2016-02-24 东北农业大学 治疗结肠炎的组合物、药物及其制备方法
CN105420150A (zh) * 2015-12-08 2016-03-23 东北农业大学 一种嗜酸乳杆菌及其应用
CN105586299A (zh) * 2016-03-14 2016-05-18 青岛东海药业有限公司 嗜酸乳杆菌制剂及其应用
JP5941445B2 (ja) * 2013-08-30 2016-06-29 森永乳業株式会社 Ｄ−アミノ酸の製造方法

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CN105343133B (zh) * 2015-12-08 2019-11-19 东北农业大学 一种治疗溃疡性结肠炎的复合益生菌、药物及其制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
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JP5941445B2 (ja) * 2013-08-30 2016-06-29 森永乳業株式会社 Ｄ−アミノ酸の製造方法
CN104928206A (zh) * 2015-04-29 2015-09-23 东北农业大学 一株具有高胆酸盐水解酶活性的嗜酸乳杆菌及其应用
CN105343132A (zh) * 2015-12-08 2016-02-24 东北农业大学 治疗结肠炎的组合物、药物及其制备方法
CN105420150A (zh) * 2015-12-08 2016-03-23 东北农业大学 一种嗜酸乳杆菌及其应用
CN105586299A (zh) * 2016-03-14 2016-05-18 青岛东海药业有限公司 嗜酸乳杆菌制剂及其应用

Non-Patent Citations (2)

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CHOI, EA等: "Cholesterol-lowering effects of a putative probiotic strain Lactobacillus plantarum EM isolated from kimchi", 《LWT-FOOD SCIENCE AND TECHNOLOGY》 *
徐敏等: "具有高抗胃肠道胁迫嗜酸乳杆菌的筛选及对肠炎小鼠的治疗作用", 《食品工业科技》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114231470A (zh) * 2022-01-26 2022-03-25 江南大学 一株可缓解溃疡性结肠炎的嗜酸乳杆菌及其应用
CN114672436A (zh) * 2022-04-07 2022-06-28 重庆医科大学 一株嗜酸乳杆菌及其应用
CN114672436B (zh) * 2022-04-07 2024-04-16 重庆医科大学 一株嗜酸乳杆菌及其应用
CN114574543A (zh) * 2022-04-12 2022-06-03 广西南宁佰奥吉生物科技有限公司 一种耐高温的乳酸菌选育方法
CN117305188A (zh) * 2023-11-27 2023-12-29 山东中微众康生物科技有限公司 促进儿童骨生长的嗜酸乳杆菌RZKLa0701及其应用
CN117305188B (zh) * 2023-11-27 2024-02-13 山东中微众康生物科技有限公司 促进儿童骨生长的嗜酸乳杆菌RZKLa0701及其应用

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CN110023486B (zh) 2022-02-22

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Application publication date: 20190716

Assignee: BGI PRECISION NUTRITION (SHENZHEN) TECHNOLOGY CO.,LTD.

Assignor: BGI SHENZHEN

Contract record no.: X2022440020021

Denomination of invention: A Lactobacillus acidophilus and its culture method and application

Granted publication date: 20220222

License type: Common License

Record date: 20221107