CN110004027A - A kind of gene sequencer automatic leveling objective table - Google Patents
A kind of gene sequencer automatic leveling objective table Download PDFInfo
- Publication number
- CN110004027A CN110004027A CN201910304915.4A CN201910304915A CN110004027A CN 110004027 A CN110004027 A CN 110004027A CN 201910304915 A CN201910304915 A CN 201910304915A CN 110004027 A CN110004027 A CN 110004027A
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- CN
- China
- Prior art keywords
- objective table
- fixed
- automatic leveling
- horizontal ruler
- gene sequencer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Abstract
The invention discloses a kind of gene sequencer automatic leveling objective tables, including pedestal, screw pitch trimmer, power device, image acquisition device, cross horizontal ruler, controller and objective table；The objective table is fixed on the base by three screw pitch trimmers not on the same line；Described screw pitch trimmer one end is rotatably connected on objective table bottom surface, and the other end is fixed on the base by power device, and the power device includes the retarder of micro-machine and connecting screw range regulator and micro-machine；The cross horizontal ruler is fixed on objective table bottom center position；Described image collector is fixed on base top surface and cross horizontal ruler position is corresponding；The controller is fixed on the base, and is connected with three power devices and image acquisition device；The characteristics of present invention has structure simple, reliable performance, automatic leveling.
Description
Technical field
The present invention relates to gene sequencer automatic leveling objective tables.
Background
Gene sequencing technology is to detect nucleic acid by gene sequencer, obtains nucleic acid sequence by data processing.At present
Gene sequencer, sequencing procedure by a series of machinery, electronic communication, biology, chemistry, optics etc. operation formed, it is to be checked
It surveys DNA fragmentation sample to be arranged in the reaction small chamber of gene sequencer and carries out sequencing reaction, reaction reagent passes through reaction when sequencing
Channel flows through sequencing reaction small chamber and sequencing reaction occurs for sample to be tested.It is surveyed after sequencing reaction by image acquisition device
Sequence Image Acquisition obtains gene order by post-processing.
Requirement due to gene sequencing to precision is very high, belongs to micron order, and deviation occurs in the operation of any one component
Result will be caused undesirable, therefore, gene sequencer will level example platform before carrying out Image Acquisition, make figure
As region to be collected is on the same horizontal plane, to guarantee the clarity of the sequencing image of acquisition.Currently, in the prior art
In, the example platform of gene sequencer needs to adjust the levelness of example platform repeatedly, using manually adjusting to protect in test
Card sample to be tested is in same level, this debugging process needs repeatedly manually adjust, and adjustment analytic process also needs at present
It largely manually to participate in, require a great deal of time, debugging process is complicated, time-consuming, is unfavorable for realizing quick
Gene sequencing.Thus need a kind of self-level(l)ing device and method, solve the above problem, guarantee it is efficient realize it is automatic
Leveling sequencing reflection cell, guarantees that sequencing procedure smoothly, efficiently carries out.
Summary of the invention
The purpose of the present invention is to solve the above the deficiencies in the prior art, provide a kind of gene sequencer automatic leveling load
Object platform.
The technical scheme adopted by the invention is that a kind of such, gene sequencer automatic leveling objective table, including pedestal,
Screw pitch trimmer, power device, image acquisition device, cross horizontal ruler, controller and objective table；The objective table passes through three not
Screw pitch trimmer on the same line is fixed on the base；Described screw pitch trimmer one end is rotatably connected on objective table bottom surface,
The other end is fixed on the base by power device, the power device include micro-machine and connecting screw range regulator with it is small-sized
The retarder of motor；The cross horizontal ruler is fixed on objective table bottom center position；Described image collector is fixed on pedestal
Top surface and cross horizontal ruler position are corresponding；The controller is fixed on the base, and is adopted with three power devices and image
Storage is connected.
Preferably, the screw pitch trimmer is connected by universal shaft with objective table bottom surface.
Preferably, described image collector is high-definition camera.
Preferably, cross glass tube is provided on the cross horizontal ruler, glass tube is equipped with ethylene glycol, alcohol, water
With the mixing liquid of glycerol and there are bubbles.
Preferably, the micro-machine is RisymR300C miniature DC motor.
The utility model has the advantages that
Genetic chip is fixed on objective table by the present invention, then by image acquisition device in real time to the ten of objective table bottom
Word horizontal ruler carries out Image Acquisition, and image information is then passed to controller, and controller is according to the position control of vacuole in image
Three power device adjustment screw range regulators adjust stage position, until bubble rests on central portion in cross horizontal ruler
Position then represents objective table level；The characteristics of present invention has structure simple, reliable performance, automatic leveling.
Detailed description of the invention
Fig. 1 is structure of the invention figure；
Fig. 2 is objective table bottom view of the present invention；
1. pedestal, 2. screw pitch trimmers, 3. power devices, 4. image acquisition devices,
5. cross horizontal ruler, 6. controllers, 7. objective tables, 8. universal shafts
Specific embodiment
In order to deepen the understanding of the present invention, below in conjunction with embodiment and attached drawing, the invention will be further described, should
The examples are only for explaining the invention, is not intended to limit the scope of the present invention..
As shown in Figs. 1-2, a kind of gene sequencer automatic leveling objective table, including pedestal 1, screw pitch trimmer 2, power dress
Set 3, image acquisition device 4, cross horizontal ruler 5, controller 6 and objective table 7；The objective table 7 is by three not in same straight line
On screw pitch trimmer 2 be fixed on pedestal 1；Described 2 one end of screw pitch trimmer is rotatably connected on 7 bottom surface of objective table, the other end
Be fixed on pedestal 1 by power device 3, the power device 3 include micro-machine and connecting screw range regulator 2 with it is small-sized
The retarder of motor；The cross horizontal ruler 5 is fixed on 7 bottom center position of objective table；Described image collector 4 is fixed on bottom
1 top surface of seat and 5 position of cross horizontal ruler are corresponding；The controller 6 is fixed on pedestal 1, and with three power devices 3 with
And image acquisition device 4 is connected.
In the present embodiment, the screw pitch trimmer 2 is connected by universal shaft 8 with 1 bottom surface of objective table, and described image is adopted
Storage 4 is high-definition camera, and cross glass tube is provided on the cross horizontal ruler 5, and glass tube is equipped with ethylene glycol, wine
Essence, the mixing liquid of water and glycerol and there are bubble, the micro-machine is RisymR300C miniature DC motor.
When in use, the genetic chip made is mounted on objective table first, then controller 6 is adopted according to image
The image of the collected 7 bottom cross horizontal ruler 5 of objective table of storage 4, controls three power devices, 3 adjustment screw range regulator 2, from
And the position of objective table 7 is adjusted, and until bubble rests on central part in cross horizontal ruler 5, then 7 level of objective table is represented, it is complete
At automatic leveling.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (5)
1. a kind of gene sequencer automatic leveling objective table, which is characterized in that including pedestal, screw pitch trimmer, power device, figure
As collector, cross horizontal ruler, controller and objective table；The objective table passes through three screw rod roll adjustments not on the same line
Device is fixed on the base；Described screw pitch trimmer one end is rotatably connected on objective table bottom surface, and the other end is fixed by power device
On pedestal, the power device includes the retarder of micro-machine and connecting screw range regulator and micro-machine；The cross
Horizontal ruler is fixed on objective table bottom center position；Described image collector is fixed on base top surface and cross horizontal ruler position
It is corresponding；The controller is fixed on the base, and is connected with three power devices and image acquisition device.
2. gene sequencer automatic leveling objective table as described in claim 1, which is characterized in that the screw pitch trimmer passes through
Universal shaft is connected with objective table bottom surface.
3. gene sequencer automatic leveling objective table as described in claim 1, which is characterized in that described image collector is height
Clear camera.
4. gene sequencer automatic leveling objective table as described in claim 1, which is characterized in that set on the cross horizontal ruler
It is equipped with cross glass tube, the mixing liquid of ethylene glycol, alcohol, water and glycerol is housed glass tube and there are bubbles.
5. gene sequencer automatic leveling objective table as described in claim 1, which is characterized in that the micro-machine is
RisymR300C miniature DC motor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910304915.4A CN110004027A (en) | 2019-04-16 | 2019-04-16 | A kind of gene sequencer automatic leveling objective table |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910304915.4A CN110004027A (en) | 2019-04-16 | 2019-04-16 | A kind of gene sequencer automatic leveling objective table |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110004027A true CN110004027A (en) | 2019-07-12 |
Family
ID=67172377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910304915.4A Pending CN110004027A (en) | 2019-04-16 | 2019-04-16 | A kind of gene sequencer automatic leveling objective table |
Country Status (1)
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| CN (1) | CN110004027A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111019824A (en) * | 2019-12-16 | 2020-04-17 | 浙江卫未生物医药科技有限公司 | Automatic level machine suitable for cell culture |
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| CN107881095A (en) * | 2016-09-30 | 2018-04-06 | 广州康昕瑞基因健康科技有限公司 | The leveling structure of sequencing reaction device |
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| JP2002533771A (en) * | 1998-12-21 | 2002-10-08 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Language model based on speech recognition history |
| CN102112594A (en) * | 2008-08-01 | 2011-06-29 | 智能生物系统公司 | A sample port of a cell culture system |
| WO2017024893A1 (en) * | 2015-08-07 | 2017-02-16 | 广州康昕瑞基因健康科技有限公司 | Genetic sequencer, and automatic levelling apparatus and method |
| CN106434272A (en) * | 2015-08-07 | 2017-02-22 | 广州康昕瑞基因健康科技有限公司 | Gene sequencer, automatic leveling apparatus and automatic leveling method |
| CN105702143A (en) * | 2016-04-01 | 2016-06-22 | 杨溢 | Tracking leveling type spectrometer |
| CN107881095A (en) * | 2016-09-30 | 2018-04-06 | 广州康昕瑞基因健康科技有限公司 | The leveling structure of sequencing reaction device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111019824A (en) * | 2019-12-16 | 2020-04-17 | 浙江卫未生物医药科技有限公司 | Automatic level machine suitable for cell culture |
| CN111019824B (en) * | 2019-12-16 | 2024-02-02 | 浙江卫未生物医药科技有限公司 | Automatic level machine suitable for cell culture |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190712 |
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| RJ01 | Rejection of invention patent application after publication |