CN111019824B - Automatic level machine suitable for cell culture - Google Patents

Automatic level machine suitable for cell culture Download PDF

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Publication number
CN111019824B
CN111019824B CN201911290879.7A CN201911290879A CN111019824B CN 111019824 B CN111019824 B CN 111019824B CN 201911290879 A CN201911290879 A CN 201911290879A CN 111019824 B CN111019824 B CN 111019824B
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China
Prior art keywords
cambered surface
cell culture
leveling
placing platform
groove
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CN201911290879.7A
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CN111019824A (en
Inventor
陈锦阳
刘军权
吴小佳
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Weiwei Hangzhou Regenerative Medicine Technology Co ltd
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Zhejiang Healthfuture Biomedical Technology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01CMEASURING DISTANCES, LEVELS OR BEARINGS; SURVEYING; NAVIGATION; GYROSCOPIC INSTRUMENTS; PHOTOGRAMMETRY OR VIDEOGRAMMETRY
    • G01C9/00Measuring inclination, e.g. by clinometers, by levels
    • G01C9/12Measuring inclination, e.g. by clinometers, by levels by using a single pendulum plumb lines G01C15/10
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00Tissue, human, animal or plant cell, or virus culture apparatus

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Virology (AREA)
  • Remote Sensing (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention relates to the technical field of leveling machines, in particular to an automatic leveling machine suitable for cell culture, which comprises a placing platform, wherein a leveling component is arranged at the center of the bottom of the placing platform, a leveling part is arranged in the middle of the leveling component, the leveling part comprises a weight body, adaptive supporting components are vertically arranged at the bottom of the placing platform and close to four corners, and each adaptive supporting component comprises a rectangular fixing block. This automatic level machine suitable for cell culture, the plumb bob in the horizontal component can remain plumb all the time because of self weight to can be with placing platform automatic positioning to the horizontal plane, rethread adaptability supporting component will placing platform's fixed in position makes placing platform can regard as interim operation panel, ensures that the cell culture bottle places on the horizontal plane, avoids appearing that the uneven cell inoculation leads to the regional cell of partial too early to reach the problem of maximum density, has also reduced technician's work load and culture cost simultaneously.

Description

Automatic level machine suitable for cell culture
Technical Field
The invention relates to the technical field of leveling machines, in particular to an automatic leveling machine suitable for cell culture.
Background
At present, the application of cells is more and more extensive, but the uneven bracket of a cell culture box body exists in the process of culturing the cells, so that the cells are automatically collected from high positions to low positions due to being placed on the uneven bracket after resuscitating and inoculating, and finally, the uneven cell inoculation is caused. Along with the proliferation of cells, partial cells in a partial area of a culture flask can reach extremely high density too early due to uneven cell inoculation, so that technicians have to choose to conduct cell passage treatment in advance, and the workload and the culture cost of the technicians are increased. In view of this, we propose an automatic level machine suitable for cell culture.
Disclosure of Invention
The present invention is directed to an automatic leveling machine suitable for cell culture, which solves the above-mentioned problems of the prior art.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the utility model provides an automatic level machine suitable for cell culture, includes place platform, place platform's four sides all are vertical to be equipped with the baffle, place platform's bottom center department is equipped with the level subassembly that adjusts, the level subassembly that adjusts includes the base, place platform's surface and be close to the equal vertical first support column that is equipped with in position of four corners, the top of first support column is equipped with the roof, first cambered surface logical groove has been seted up in the center department of roof, swing joint has the horizontal component in the first cambered surface logical groove, the horizontal component includes the weight body, the vertical welding in top of weight body has the head rod, the top welding of head rod has first pivot body, the top welding of first pivot body has the second connecting rod, the top of second connecting rod with place platform's bottom bonds, place platform's bottom and be close to the equal vertical adaptation supporting component that is equipped with in position of four corners, the side of rectangle fixed block and the position that is located the bottom edge are equipped with the lug, the middle part swing joint in the lug outside has the horizontal component, the cylindrical connecting rod has the rectangular fastening piece in the top of cylindrical slot, cylindrical slot has the cylindrical top of cylindrical connecting rod has the cylindrical slot, the cylindrical top of cylindrical connecting rod has the cylindrical slot in the cylindrical top of the cylindrical slot.
Preferably, a spherical rubber block is arranged at the bottom of the supporting rod, and the top end of the supporting rod is in sliding connection with the rectangular fixing block.
Preferably, the end part of the fastening bolt is provided with an annular fixing block, the annular fixing block is located in the cylindrical groove and is in sliding connection with the cylindrical groove, and the end part of the fastening bolt is attached to the circumferential outer wall of the supporting rod.
Preferably, the mounting includes the fixed plate, the fixed plate with place platform threaded connection, arc recess has been seted up to the bottom center department of fixed plate, the shape of arc recess with the shape looks adaptation on second pivot body top, the bottom of fixed plate and the position that is close to four corners are all vertical to be equipped with the second support column, the bottom of second support column is equipped with the backup pad, the surface center department of backup pad has seted up the second cambered surface and has led to the groove, the cambered surface of second cambered surface lead to the groove with the cambered surface looks adaptation of the lower part in the second pivot body, the second pivot body with the backup pad rotates to be connected.
Preferably, the cambered surface of the first cambered surface through groove is matched with the cambered surface of the middle lower part of the first rotating shaft body, and the first rotating shaft body is rotationally connected with the top plate.
Preferably, the weight body is located in the middle of the leveling component.
Compared with the prior art, the invention has the beneficial effects that:
this automatic level machine suitable for cell culture, the plumb bob in the horizontal component can remain plumb all the time because of self weight to can be with placing platform automatic positioning to the horizontal plane, rethread adaptability supporting component will placing platform's fixed in position makes placing platform can regard as interim operation panel, ensures that the cell culture bottle places on the horizontal plane, avoids appearing that the uneven cell inoculation leads to the regional cell of partial too early to reach the problem of maximum density, has also reduced technician's work load and culture cost simultaneously.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present invention;
FIG. 2 is a schematic view of a leveling component according to the present invention;
FIG. 3 is a schematic view of a partial cross-sectional structure of a leveling component according to the present invention;
FIG. 4 is a schematic view of the structure of the adaptive support assembly according to the present invention;
FIG. 5 is a schematic view of a partial cross-sectional structure of the adaptive support assembly of the present invention;
FIG. 6 is an enlarged view at A in the present invention;
fig. 7 is a schematic structural view of a fixing member in the present invention.
In the figure: the device comprises a placing platform 1, a baffle 10, a leveling component 2, a base 20, a first supporting column 21, a top plate 22, a first cambered surface through groove 220, a horizontal piece 23, a heavy hammer body 230, a first connecting rod 231, a first rotating shaft body 232, a second connecting rod 233, an adaptive supporting component 3, a rectangular fixing block 30, a convex block 300, a third connecting rod 301, a second rotating shaft body 302, a cylindrical slot 303, a cylindrical groove 3030, a supporting rod 31, a spherical rubber block 310, a fixing piece 32, a fixing plate 320, a cambered surface groove 3200, a supporting plate 321, a second cambered surface through groove 3210, a second supporting column 322, a fastening bolt 33 and an annular fixing block 330.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", or a third "may explicitly or implicitly include one or more such feature. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
Referring to fig. 1 to 7, the present invention provides a technical solution:
an automatic leveling machine suitable for cell culture comprises a placement platform 1, wherein baffle plates 10 are vertically arranged on four sides of the placement platform 1, the baffle plates 10 can prevent cell culture bottles temporarily placed on the placement platform 1 from sliding down, the safety of the cell culture bottles is ensured, a leveling component 2 is arranged at the center of the bottom of the placement platform 1, the leveling component 2 comprises a base 20, the automatic leveling machine is supported by the base 20, a first supporting column 21 is vertically arranged on the surface of the base 20 and near four corners, a top plate 22 is arranged at the top of the first supporting column 21, a first cambered surface through groove 220 is formed in the center of the top plate 22, a horizontal piece 23 is movably connected in the first cambered surface through groove 220, the top plate 22 supports the horizontal piece 23, the horizontal piece 23 comprises a weight body 230, the weight body 230 always maintains a plumb because of self weight, thereby the placing platform 1 is automatically and horizontally positioned, the top of the weight body 230 is vertically welded with a first connecting rod 231, the top of the first connecting rod 231 is welded with a first rotating shaft body 232, the top of the first rotating shaft body 232 is welded with a second connecting rod 233, the top of the second connecting rod 233 is adhered to the bottom of the placing platform 1, the placing platform 1 moves along with the weight body 230 through the second connecting rod 233, the bottom of the placing platform 1 and the positions close to four corners are vertically provided with adaptive support assemblies 3, when the placing platform 1 is horizontally positioned through the adaptive support assemblies 3, the height of the four support rods 31 can be automatically adjusted, the four support rods 31 are always kept in contact with the ground, after the horizontal positioning is convenient, the support rods 31 are fixed, thereby the position of the placing platform 1 is fixed, the adaptive support assemblies 3 comprise rectangular fixing blocks 30, the side of rectangle fixed block 30 and the position that is located the bottom edge are equipped with lug 300, the middle part swing joint in the lug 300 outside has fastening bolt 33, cylindrical slot 303 has been seted up vertically to the bottom of rectangle fixed block 30, cylindrical recess 3030 has been seted up to the inner wall of cylindrical slot 303 and the position that is close to the opening part, fastening bolt 33's tip passes lug 300 to cylindrical recess 3030 in, swing joint has bracing piece 31 in the cylindrical slot 303, bracing piece 31 plays the supporting role, the top of rectangle fixed block 30 is equipped with third connecting rod 301, the top welding of third connecting rod 301 has second pivot body 302, the top of rectangle fixed block 30 is equipped with mounting 32, second pivot body 302 is located mounting 32, can make bracing piece 31 keep plumb state through second pivot body 302.
In this embodiment, the bottom of the supporting rod 31 is provided with a spherical rubber block 310, the spherical rubber block 310 can prevent the supporting rod 31 from sliding on the ground, and the top end of the supporting rod 31 is slidably connected with the rectangular fixing block 30, so that the supporting rod 31 can automatically adjust the height while adjusting the horizontal position along with the placement platform 1.
Specifically, the end of the fastening bolt 33 is provided with an annular fixing block 330, the annular fixing block 330 is located in the cylindrical groove 3030 and is slidably connected with the cylindrical groove 3030, the annular fixing block 330 can prevent the fastening bolt 33 from falling off from the protruding block 300, the end of the fastening bolt 33 is attached to the circumferential outer wall of the supporting rod 31, and the supporting rod 31 can be fixed in the cylindrical groove 3030 through the fastening bolt 33, so that the supporting rod 31 and the rectangular fixing block 30 are fixed in position.
Further, the fixing piece 32 comprises a fixing plate 320, the fixing plate 320 is in threaded connection with the placing platform 1, the adaptive support assembly 3 is fixed at the bottom of the placing platform 1 through the fixing plate 320, the arc-shaped groove 3200 is formed in the center of the bottom of the fixing plate 320, the shape of the arc-shaped groove 3200 is matched with that of the top end of the second rotating shaft body 302, the fixing plate 320 can prevent the second rotating shaft body 302 from moving up and down in the fixing piece 32, the situation that the second rotating shaft body 302 cannot be fixed due to the fact that the second rotating shaft body 302 can move up and down in the fixing piece 32 after the placing platform 1 is horizontally positioned is ensured, the second support columns 322 are vertically arranged at the bottom of the fixing plate 320 and close to four corners, the bottom of each second support column 322 is provided with a support plate 321, a second arc-shaped through groove 3210 is formed in the center of the surface of each support plate 321, the arc-shaped surface of each second arc-shaped through groove 3210 is matched with that of the arc-shaped surface of the lower portion of the second rotating shaft body 302, the second rotating shaft body 302 is rotationally connected with the support plate 321, and the second rotating shaft body 302 can adaptively adjust the position in the second arc-shaped through groove 3210, and the lead state of each support bar 31 is kept.
Further, the cambered surface of the first cambered surface through groove 220 is matched with the cambered surface of the middle lower part of the first rotating shaft body 232, and the first rotating shaft body 232 is rotationally connected with the top plate 22, so that the first rotating shaft body 232 can be adaptively adjusted in position in the first cambered surface through groove 220, and the weight body 230 drives the placing platform 1 to be automatically and horizontally positioned.
In addition, the weight body 230 is located in the middle of the leveling component 2, so that the first connecting rod 231 does not block the weight body 230 while keeping the plumb state.
When the automatic leveling machine suitable for cell culture of this embodiment is used, the user rotates the fastening bolts 33 in the four adaptive support assemblies 3 anticlockwise to separate the ends of the four adaptive support assemblies 3 from the supporting rods 31, at this time, the weight body 230 can always keep horizontal due to its own weight, the weight body 230 drives the first rotating shaft body 232 to rotate in the first cambered surface through groove 220 to adjust the position until reaching the horizontal position, the height of the four adaptive support assemblies 3 is also adjusted along with the rotation of the second rotating shaft body 302 in the second cambered surface through groove 3210 of the fixing piece 32 during the horizontal adjustment of the placement platform 1, so that the supporting rods 31 keep the plumb state, the placement platform 1 finally reaches the horizontal state under the action of the weight body 230, at this time, the positions of the four adaptive support assemblies 3 are also stabilized, the user rotates the four fastening bolts 33 clockwise to squeeze the supporting rods 31, and fix the positions of the supporting rods 31 and the rectangular fixing blocks 30, so that the height of the adaptive support assemblies 3 is fixed, the position of the placement platform 1 can not change any more, and then the user can place cells on the temporary placement platform 1 as a protective bottle 1, and can be placed on the temporary bottle 1.
The foregoing has shown and described the basic principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the above-described embodiments, and that the above-described embodiments and descriptions are only preferred embodiments of the present invention, and are not intended to limit the invention, and that various changes and modifications may be made therein without departing from the spirit and scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (4)

1. Automatic leveling machine suitable for cell culture, including place platform (1), its characterized in that: four sides of place platform (1) are all vertical baffle (10) that are equipped with, the bottom center department of place platform (1) is equipped with level adjustment subassembly (2), level adjustment subassembly (2) are including base (20), the surface of base (20) and the position that is close to four corners are all vertical be equipped with first support column (21), the top of first support column (21) is equipped with roof (22), first cambered surface logical groove (220) have been seted up to the center department of roof (22), swing joint has horizontal spare (23) in first cambered surface logical groove (220), horizontal spare (23) include weight body (230), the top vertical welding of weight body (230) has head rod (231), the top welding of head rod (231) has first pivot body (232), the top welding of head rod (232) has second connecting rod (233), the top of second connecting rod (233) with the bottom of place platform (1) bonds the bottom of place platform (1) and has seted up first cambered surface logical groove (220), the bottom of placing platform (1) and being close to four positions that are equipped with vertical supporting block (3) and be equipped with rectangle supporting component (30) and adaptability (30) are located fixed position (30), the middle part outside the lug (300) is movably connected with a fastening bolt (33), a cylindrical slot (303) is vertically formed in the bottom of the rectangular fixing block (30), a cylindrical groove (3030) is formed in the inner wall of the cylindrical slot (303) and close to the position of the opening, the end part of the fastening bolt (33) penetrates through the lug (300) to the inside of the cylindrical groove (3030), a supporting rod (31) is movably connected in the cylindrical slot (303), a third connecting rod (301) is arranged at the top of the rectangular fixing block (30), a second rotating shaft body (302) is welded at the top of the third connecting rod (301), a fixing piece (32) is arranged above the rectangular fixing block (30), and the second rotating shaft body (302) is positioned in the fixing piece (32); the bottom of the supporting rod (31) is provided with a spherical rubber block (310), and the top end of the supporting rod (31) is in sliding connection with the rectangular fixed block (30); the end part of the fastening bolt (33) is provided with an annular fixing block (330), the annular fixing block (330) is positioned in the cylindrical groove (3030) and is in sliding connection with the cylindrical groove (3030), and the end part of the fastening bolt (33) is attached to the circumferential outer wall of the supporting rod (31).
2. The automatic level machine for cell culture according to claim 1, wherein: mounting (32) are including fixed plate (320), fixed plate (320) with place platform (1) threaded connection, arc recess (3200) have been seted up to the bottom center department of fixed plate (320), the shape of arc recess (3200) with the shape looks adaptation on second pivot body (302) top, the bottom of fixed plate (320) and the position that is close to four corners are all vertical to be equipped with second support column (322), the bottom of second support column (322) is equipped with backup pad (321), second cambered surface logical groove (3210) have been seted up in the surface center department of backup pad (321), cambered surface logical groove (3210) of second cambered surface with cambered surface looks adaptation of lower part in second pivot body (302), second pivot body (302) with backup pad (321) rotate and are connected.
3. The automatic level machine for cell culture according to claim 1, wherein: the cambered surface of the first cambered surface through groove (220) is matched with the cambered surface at the middle lower part of the first rotating shaft body (232), and the first rotating shaft body (232) is rotationally connected with the top plate (22).
4. The automatic level machine for cell culture according to claim 1, wherein: the heavy hammer body (230) is positioned in the middle of the leveling component (2).
CN201911290879.7A 2019-12-16 2019-12-16 Automatic level machine suitable for cell culture Active CN111019824B (en)

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Application Number Priority Date Filing Date Title
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CN111019824B true CN111019824B (en) 2024-02-02

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113176621B (en) * 2021-04-14 2022-10-18 山东省科学院海洋仪器仪表研究所 Ocean upper water vapor concentration detection device

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KR20090056667A (en) * 2007-11-30 2009-06-03 코아스템(주) The cell culture apparatus and mass automatic cell culture device having it
CN104729479A (en) * 2015-03-31 2015-06-24 绍兴文理学院 Multifunctional mechanical gradienter
CN106370163A (en) * 2016-08-26 2017-02-01 成都晨越造价咨询有限公司 Measuring device for construction project cost budget
CN106969757A (en) * 2017-04-09 2017-07-21 柯富荣 A kind of automatic leveling tripod
CN110004027A (en) * 2019-04-16 2019-07-12 北京龙基高科生物科技有限公司 A kind of gene sequencer automatic leveling objective table
CN209589054U (en) * 2019-02-02 2019-11-05 刘东旭 A kind of geotechnical engineering geology instrument of surveying and mapping

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Publication number Priority date Publication date Assignee Title
US6584913B2 (en) * 2001-01-19 2003-07-01 William Cloud Portable adjustable work station

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090056667A (en) * 2007-11-30 2009-06-03 코아스템(주) The cell culture apparatus and mass automatic cell culture device having it
CN104729479A (en) * 2015-03-31 2015-06-24 绍兴文理学院 Multifunctional mechanical gradienter
CN106370163A (en) * 2016-08-26 2017-02-01 成都晨越造价咨询有限公司 Measuring device for construction project cost budget
CN106969757A (en) * 2017-04-09 2017-07-21 柯富荣 A kind of automatic leveling tripod
CN209589054U (en) * 2019-02-02 2019-11-05 刘东旭 A kind of geotechnical engineering geology instrument of surveying and mapping
CN110004027A (en) * 2019-04-16 2019-07-12 北京龙基高科生物科技有限公司 A kind of gene sequencer automatic leveling objective table

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Address after: Room 101, Building 10, No. 365 Changjiang Road, Changhe Street, Binjiang District, Hangzhou City, Zhejiang Province 310000

Patentee after: Weiwei (Hangzhou) Regenerative Medicine Technology Co.,Ltd.

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Address before: Room 201, 2nd Floor, Building 2, No. 288 Qiuyi Road, Changhe Street, Hangzhou City, Zhejiang Province, 310000

Patentee before: ZHEJIANG HEALTHFUTURE BIOMEDICAL TECHNOLOGY CO.,LTD.

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