CN109966363A - A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is scattered - Google Patents

A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is scattered Download PDF

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CN109966363A
CN109966363A CN201711464361.1A CN201711464361A CN109966363A CN 109966363 A CN109966363 A CN 109966363A CN 201711464361 A CN201711464361 A CN 201711464361A CN 109966363 A CN109966363 A CN 109966363A
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sachalinense
phellodendron
sichuan
china
rhizoma coptidis
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李晓静
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
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Abstract

The invention discloses a kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sores to dissipate, it is with RHIZOMA COPTIDIS from Sichuan of China 14%~16%, Phellodendron sachalinense 14%~16%, radix scutellariae 13%~15%, catechu 12%~14%, garden burnet 11%~13%, indigo naturalis 11%~13%, Chinese gall 6%~8%, borneol 6%~8%, alumen 4%~6% is raw material, by drying, it crushes, extraction, RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is mixed with out to dissipate, with eliminating dampness heat-clearing, purging fire for removing toxin, hygroscopic myogenic sore, cooling blood and hemostasis, it is clearing heat and detoxicating, the effect of healing up sore and subduing swelling, cure mainly thrush, and it is significant in efficacy, it has no adverse reaction, it is without side-effects.

Description

A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is scattered
Technical field
The present invention relates to the technical field of Chinese medicine, espespecially a kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore dissipates.
Background technique
Thrush also known as moniliasis white mouth, it is white read bacterium disease, be a kind of common disease of Pediatric Oral Emergency by fungal infection.In oral cavity Mucous membrane surface forms leukasmus film, is more common in infant.This disease is caused by candida albicans infection.This fungi sometimes may be used It finds, can fall ill when infant nutrition is bad or physical decline in the oral cavity；Thrush is more common in weak or underfed Infant, especially dyspeptic infant are Anywhere likely to that thrush can occur in oral cavity, and newborn is mostly by producing Road infection, it is also possible to be because the nipple or rubber nipple of the finger infection mother of the unclean perhaps nursing person of teat are all The source of infection.Being mainly shown as has the color Bai Ruxue being dispersed in upperlip, cheek mucous membrane, back or soft palate etc. mucous hyperemia Soft fleck, can merge into each other into soon white velvet shape patch.Patch attachment is not very close, slightly firmly erasable Fall.Typically no simultaneous phenomenon, but there is part infant to will appear dysphoria, crying, dysilthia, sometimes also with slight hair Heat.
Summary of the invention
A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore of the present invention dissipates, using Chinese medicine RHIZOMA COPTIDIS from Sichuan of China, Phellodendron sachalinense, radix scutellariae, catechu, Elm, indigo naturalis, Chinese gall, borneol, alumen are raw material, by drying, crushing, extract, are mixed with out RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic Sore dissipates, it can be achieved that quickly treating the purpose of thrush.
To achieve the goals above, the technical solution of the invention is as follows: what a kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore dissipated Main ingredient composition: RHIZOMA COPTIDIS from Sichuan of China 14%~16%, Phellodendron sachalinense 14%~16%, radix scutellariae 13%~15%, catechu 12%~14%, garden burnet 11%~ 13%, indigo naturalis 11%~13%, Chinese gall 6%~8%, borneol 6%~8%, alumen 4%~6%.
Technique preparation step is as follows:
(1) dry: main ingredient composition being cleaned respectively, cleans, dry；
(2) crush: being crushed respectively using pulverizer main ingredient composition；With 60 mesh sieves；
(3) extract: using supercritical extracting equipment device, main ingredient composition is respectively put into supercritical CO2The extraction of extraction equipment In kettle, supercritical CO is added2For extractant, 30 DEG C~50 DEG C of extraction temperature, extracting pressure 15Mpa~30Mpa, extract Time is 4h~6h, is then separated using heating, decompression, and the extraction that product in separating still obtains main ingredient composition respectively is collected Powder；
(4) mix: raw material components being packed into proportion in the efficiently asymmetric mixing machine of V-type, 12 turns/min of speed of agitator,
The incorporation time min of 8 min~10 dissipates to get RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore.
Main ingredient composition effect of the present invention and effect:
RHIZOMA COPTIDIS from Sichuan of China: have effects that the symptoms such as eliminating dampness heat-clearing, purging fire for removing toxin；
Phellodendron sachalinense: with wind-dispelling promoting the circulation of qi, cold dispelling for oral administration, disappear stagnant, benefiting stomach and stopping pain；External application Xiaofeng San gas；Heart and stomach pain, cold sense Emit, influenza, flu-prevention, food stagnation stomach trouble, hernia etc. symptom the effect of；
Radix scutellariae: there is heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention, blood pressure lowering；For damp-warm syndrome, heat temperature chest tightness and emesis, damp and hot ruffian Completely, the effect of dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, the symptoms such as threatened abortion；
Catechu: there is hygroscopic myogenic sore；For unhealing ulcer, eczema, aphtha, the pain of injury caused by falling and tumbling, the function of the symptoms such as traumatic hemorrhage Effect；
Garden burnet: there is cooling blood and hemostasis, clearing heat and detoxicating, healing up sore and subduing swelling；Haematemesis, hemoptysis, bleeding from five sense organs or subcutaneous tissue, hematuria, hematochezia, hemorrhoid blood, bloody flux collapse The effect of leakage, leukorrhea with reddish discharge, sore, carbuncle and painful swelling, eczema, pruritus vulvae, scald, the symptoms such as snakebite and bugbite；
Indigo naturalis: having energy clearing heat-fire, and removing pattogenic heat from the blood and toxic material from the body cures mainly the diseases such as hot spot, haematemesis；Sore, the symptoms such as mumps are controlled in external application The effect of；
Chinese gall: there is astringing lung-QI, hidroschesis, puckery intestines, controlling nocturnal emission with astringent drugs, hemostasis, removing toxic substances；Cure mainly chronic cough of deficiency lung, spontaneous sweating, protracted dysentery chronic diarrhea, The effect of symptoms such as rectal prolapse, spermatorrhea, gonorrhoea, various bleedings, carbuncle swells boil；
Borneol: having and lead to all keys, dissipates stagnated fire, removes screen improving eyesight, swelling and pain relieving；Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, gas Deafness is closed, the effect of sore throat, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, the symptoms such as enterobiasis；
Alumen: there is dissolving phlegm, eliminating dampness, antidiarrheal, hemostasis, removing toxic substances, desinsection；Control epilepsy, sore throat, remorse saliva stop up very, hepatitis, jaundice, Huang Swollen, duodenal ulcer, uterine prolapse, leukorrhea, dysentery, bleeding from five sense organs or subcutaneous tissue, aphthae, sore hemorrhoid scabies, the symptoms such as water, fire, insect bite Effect.
RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore of the present invention dissipates, and through clinical research, takes medicine to be contained in mouth a little every time, often Day, there is this product significant eliminating dampness heat-clearing, purging fire for removing toxin, hygroscopic myogenic sore, cooling blood and hemostasis, clearing heat and detoxicating, detumescence to hold back three times The effect of sore, cures mainly thrush, and significant in efficacy, has no adverse reaction, without side-effects.
Specific embodiment
Embodiment 1
Main ingredient composition: RHIZOMA COPTIDIS from Sichuan of China 14%, Phellodendron sachalinense 14%, radix scutellariae 13%, catechu 12%, garden burnet 13%, indigo naturalis 12%, Chinese gall 8%, ice Piece 8%, alumen 6%.
Technique preparation step is as follows:
(1) dry: main ingredient composition being cleaned respectively, cleans, dry；
(2) crush: being crushed respectively using pulverizer main ingredient composition；With 60 mesh sieves；
(3) extract: using supercritical extracting equipment device, main ingredient composition is respectively put into supercritical CO2The extraction of extraction equipment In kettle, supercritical CO is added2For extractant, 30 DEG C of extraction temperature, extracting pressure 30Mpa, extraction time 4h, then It is separated using heating, decompression, collects the extraction powder that product in separating still obtains main ingredient composition respectively.
(4) mix: raw material components being packed into proportion in the efficiently asymmetric mixing machine of V-type, 12 turns/min of speed of agitator,
8 min of incorporation time dissipates to get RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore；
Embodiment 2
Main ingredient composition: RHIZOMA COPTIDIS from Sichuan of China 15%, Phellodendron sachalinense 15%, radix scutellariae 15%, catechu 13%, garden burnet 11%, indigo naturalis 13%, Chinese gall 7%, ice Piece 6%, alumen 5%.
Technique preparation step is as follows:
(1) dry: main ingredient composition being cleaned respectively, cleans, dry；
(2) crush: being crushed respectively using pulverizer main ingredient composition；With 60 mesh sieves；
(3) extract: using supercritical extracting equipment device, main ingredient composition is respectively put into supercritical CO2The extraction of extraction equipment In kettle, supercritical CO is added2For extractant, 40 DEG C of extraction temperature, extracting pressure 20Mpa, extraction time 5h, then It is separated using heating, decompression, collects the extraction powder that product in separating still obtains main ingredient composition respectively；
(4) mix: raw material components being packed into proportion in the efficiently asymmetric mixing machine of V-type, 12 turns/min of speed of agitator,
Incorporation time 9min dissipates to get RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore.
Embodiment 3
Main ingredient composition: RHIZOMA COPTIDIS from Sichuan of China 16%, Phellodendron sachalinense 16%, radix scutellariae 14%, catechu 14%, garden burnet 12%, indigo naturalis 11%, Chinese gall 6%, ice Piece 7%, alumen 4%.
Technique preparation step is as follows:
(1) dry: main ingredient composition being cleaned respectively, cleans, dry；
(2) crush: being crushed respectively using pulverizer main ingredient composition；With 60 mesh sieves；
(3) extract: using supercritical extracting equipment device, main ingredient composition is respectively put into supercritical CO2The extraction of extraction equipment In kettle, supercritical CO is added2For extractant, 50 DEG C of extraction temperature, then extracting pressure 15Mpa, extraction time 6h are adopted It is separated with heating, decompression, collects the extraction powder that product in separating still obtains main ingredient composition respectively；
(4) mix: raw material components being packed into proportion in the efficiently asymmetric mixing machine of V-type, 12 turns/min of speed of agitator,
10 min of incorporation time dissipates to get RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore.
The above, embodiment is only that preferred embodiments of the present invention will be described, not to of the invention Range is defined, and under the premise of not departing from the spirit of the technology of the present invention, this field engineers and technicians are to skill of the invention The various changes and improvements that art scheme is made, should fall within the scope of protection determined by the claims of the present invention.

Claims (1)

1. a kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore dissipates, it is characterized in that: main ingredient composition: RHIZOMA COPTIDIS from Sichuan of China 14%~16%, Phellodendron sachalinense 14%~ 16%, radix scutellariae 13%~15%, catechu 12%~14%, garden burnet 11%~13%, indigo naturalis 11%~13%, Chinese gall 6%~8%, borneol 6%~ 8%, alumen 4%~6%.
CN201711464361.1A 2017-12-28 2017-12-28 A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is scattered Pending CN109966363A (en)

Priority Applications (1)

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CN201711464361.1A CN109966363A (en) 2017-12-28 2017-12-28 A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is scattered

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711464361.1A CN109966363A (en) 2017-12-28 2017-12-28 A kind of RHIZOMA COPTIDIS from Sichuan of China Phellodendron sachalinense hygroscopic sore is scattered

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CN109966363A true CN109966363A (en) 2019-07-05

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