CN103239675B - External preparation for treating breast diseases - Google Patents
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- CN103239675B CN103239675B CN201310140333.XA CN201310140333A CN103239675B CN 103239675 B CN103239675 B CN 103239675B CN 201310140333 A CN201310140333 A CN 201310140333A CN 103239675 B CN103239675 B CN 103239675B
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Abstract
The invention provides an external preparation for treating breast diseases. The external preparation comprises the following crude drugs in parts by weight: 19-20 parts of safflower, 5-9 parts of daemonorops draco, 10-20 parts of szechuan lovage rhizome, 8-12 parts of common burreed rhizome, 20-30 parts of glechoma longituba, 20-30 parts of myrrh, 8-12 parts of agrimonia pilosa, 15-25 parts of zedoary, 1-3 parts of propolis, 10-20 parts of peach flower, 8-12 parts of rhizoma acori graminei, 15-25 parts of dandelion and 1-5 parts of borneol. The traditional Chinese medicine preparation is strict in components and scientific in compatibility, has the functions of invigorating blood circulation and softening hard mass and dredging collaterals and removing toxicity, is capable of treating the breast diseases, such as hyperplasia of mammary glands, acute and chronic mastitis, galactocele and the like, and is short in treatment course, quick in effectiveness, easy for consolidation, safe for use and free of toxic or side effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of external preparation for the treatment of mastopathy.
Background technology
The prejudice of mastopathy history women is sick, frequently-occurring disease, and it is difficult to control for a long time, and sickness rate is up to 80%, and the sickness rate of cyclomastopathy has reached more than 60% of Women of childbearing age, and cyclomastopathy is considered to mammary gland canceration premenstrual disorders, and the rate of cancerating is more than 20%.It is the best effective method of Breast Cancer Prevention to cyclomastopathy early prevention, discovery morning and early treatment.
The method mainly expectant treatment of current treatment cystic hyperplasia of breast, based on oral drugs, but oral drugs are long for the course for the treatment of, and effect is slow, and Long-term taking medicine easily causes the injury of liver, gallbladder, stomach.The safety dispute of sex hormone drug treatment is always very large, and long-term taking has larger infringement to femaleness.Although can operative treatment for serious symptom, side effect be larger.
Summary of the invention
For the deficiency existing for prior art, the object of the present invention is to provide a kind of use safety, external preparation for mammary gland disease evident in efficacy.
Technical scheme of the present invention:
Treat an external preparation for mastopathy, the crude drug containing following mass parts: 19 ~ 20 parts, Flos Carthami, Sanguis Draxonis 5 ~ 9 parts, Rhizoma Chuanxiong 10 ~ 20 parts, Rhizoma Sparganii 8 ~ 12 parts, Herba Glechomae 20 ~ 30 parts, Myrrha 20 ~ 30 parts, Herba Agrimoniae 8 ~ 12 parts, Rhizoma Curcumae 15 ~ 25 parts, propolis 1 ~ 3 part, 10 ~ 20 parts, Flos persicae, Rhizoma Acori Graminei 8 ~ 12 parts, Herba Taraxaci 15 ~ 25 parts, Borneolum Syntheticum 1 ~ 5 part.
Wherein, Flos Carthami is the dried floral of feverfew Flos Carthami Carthamus tinctorius L..There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.
Sanguis Draxonis is that the resin that oozes out of babassu Sanguis Draxonis Daemonorops draco Bl. fruit is through being processed into.There is removing blood stasis and relieving pain, effect of hemostasia and promoting granulation.
Rhizoma Chuanxiong is the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanriong Hort..There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.
Rhizoma Sparganii is the dry tuber of Sparganiaceae plant rhizoma scirpi Sparganium stoloniferumBuch-Ham..There is removing blood stasis circulation of qi promoting, effect of removing food stagnancy pain relieving.
Herba Glechomae is the dry aerial parts of labiate HUOXUEDAN Kupr..There is dampness removing treating stranguria, heat-clearing and toxic substances removing, effect of dissipating blood stasis for subsidence of swelling.
Myrrha is the dry resin of olive subject plant Herba Violae tree or Ha Didingshu, has another name called myrrh.There is the detumescence of loose blood, effect of analgesic therapy granulation promoting.
Herba Agrimoniae is the dry aerial parts of rosaceous plant Agrimony Agrimonia pilosa Ledeb..There is astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, effect of removing toxic substances.
Rhizoma Curcumae is the dry rhizome of zingiberaceous plant Rhizoma Curcumae Curcuma phaeocaulis Val..There is circulation of qi promoting removing blood stasis, effect of removing food stagnancy pain relieving.
Propolis is the dry secretions of Apidae insecticide apis mellifera Linnaeus Apis mellifera L..There is effect of anti-inflammation, immunity moderation, antioxidation, acceleration organization healing.
Flos persicae is the dried floral of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch.There is effect of inducing diuresis to remove edema, QI invigorating lactogenesis.
Rhizoma Acori Graminei is the dry rhizome of acorus gramineus araceae plant Acorns tatarinowii Schott.Acrid in the mouth, hardship, temperature.
Herba Taraxaci is feverfew Herba Taraxaci Taraxacum mongolicum Hand-Mazz., alkali ground Herba Taraxaci Taraxacum sinicum Kitag. or belong to the dry herb of several plants together.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of inducing diuresis for treating stranguria syndrome.
Preferably,, external preparation of the present invention contains the crude drug of following mass parts: 15 parts, Flos Carthami, Sanguis Draxonis 7 parts, Rhizoma Chuanxiong 15 parts, Rhizoma Sparganii 10 parts, Herba Glechomae 25 parts, Myrrha 25 parts, Herba Agrimoniae 10 parts, Rhizoma Curcumae 20 parts, propolis 2 parts, 15 parts, Flos persicae, Rhizoma Acori Graminei 10 parts, Herba Taraxaci 20 parts, Borneolum Syntheticum 3 parts.
Also containing pharmaceutically acceptable adjuvant or carrier in described preparation.
Described preparation is frost, ointment, emulsion or emplastrum.
Treat a preparation method for the external preparation of mastopathy, comprise the steps:
(1) Flos Carthami, Sanguis Draxonis, Rhizoma Chuanxiong, Rhizoma Sparganii, Herba Glechomae, Myrrha, Herba Agrimoniae, Rhizoma Curcumae, Flos persicae, Rhizoma Acori Graminei, Herba Taraxaci is taken by formula, after Mechanical Crushing, add 2 ~ 5 times of volume 60% ~ 85% ethanol water reflux, extract, 1 ~ 3 time, each 1 ~ 2 hour;
(2) merge extractive liquid, decompression recycling ethanol, to without alcohol taste, filters, discards filtering residue, released liquor;
(3) add propolis, the Borneolum Syntheticum of formula ratio in medicinal liquid, mix homogeneously, then add pharmaceutically acceptable carrier or adjuvant, be prepared into exterior-applied formulation.
Described exterior-applied formulation comprises: frost, ointment, emulsion, emplastrum etc.
Beneficial effect of the present invention is: Chinese medicine preparation prescription of the present invention is rigorous, compatibility science, there is the effect of movable blood soft hard, Tongluo Jiedu, the mastopathy such as cyclomastopathy, acute and chronic mastitis, cyst of breast can be treated, and short treating period, instant effect, easily to consolidate, use safety, to have no side effect.
Detailed description of the invention
The present invention is explained further below in conjunction with embodiment.Should be understood that these embodiments are only not used in for illustration of the present invention to limit the scope of the invention.
Embodiment 1
Treat an external preparation for mastopathy, the crude drug containing following mass parts: 19 parts, Flos Carthami, Sanguis Draxonis 5 parts, Rhizoma Chuanxiong 10 parts, Rhizoma Sparganii 8 parts, Herba Glechomae 20 parts, Myrrha 20 parts, Herba Agrimoniae 8 parts, Rhizoma Curcumae 15 parts, propolis 1 part, 10 parts, Flos persicae, Rhizoma Acori Graminei 8 parts, Herba Taraxaci 15 parts, Borneolum Syntheticum 1 part.
Preparation method is as follows:
(1) take Flos Carthami, Sanguis Draxonis, Rhizoma Chuanxiong, Rhizoma Sparganii, Herba Glechomae, Myrrha, Herba Agrimoniae, Rhizoma Curcumae, Flos persicae, Rhizoma Acori Graminei, Herba Taraxaci by formula, after Mechanical Crushing, add 3 times of volume 65% ethanol water reflux, extract, 3 times, each 2 hours;
(2) merge extractive liquid, decompression recycling ethanol, to without alcohol taste, filters, discards filtering residue, released liquor, and medicinal liquid low-temperature reduced-pressure is dry, obtains ointment;
(3) propolis, the Borneolum Syntheticum of formula ratio is added in ointment, mix homogeneously;
(4) vaseline 40 mass parts, lanoline 25 mass parts is gone to mix post-heating to 60 DEG C, make to melt completely, add the ointment of step (3) mix homogeneously, stir, add the sodium benzoate of 0.5 mass parts again, stir, make ointment, after ultra-vioket radiation sterilizing, point packing.
Embodiment 2
Treat an external preparation for mastopathy, the crude drug containing following mass parts: 15 parts, Flos Carthami, Sanguis Draxonis 7 parts, Rhizoma Chuanxiong 15 parts, Rhizoma Sparganii 10 parts, Herba Glechomae 25 parts, Myrrha 25 parts, Herba Agrimoniae 10 parts, Rhizoma Curcumae 20 parts, propolis 2 parts, 15 parts, Flos persicae, Rhizoma Acori Graminei 10 parts, Herba Taraxaci 20 parts, Borneolum Syntheticum 3 parts.
Preparation method is as follows:
(1) take Flos Carthami, Sanguis Draxonis, Rhizoma Chuanxiong, Rhizoma Sparganii, Herba Glechomae, Myrrha, Herba Agrimoniae, Rhizoma Curcumae, Flos persicae, Rhizoma Acori Graminei, Herba Taraxaci by formula, after Mechanical Crushing, add 3 times of volume 65% ethanol water reflux, extract, 3 times, each 2 hours;
(2) merge extractive liquid, decompression recycling ethanol, to without alcohol taste, filters, discards filtering residue, released liquor, and medicinal liquid low-temperature reduced-pressure is dry, obtains ointment;
(3) propolis, the Borneolum Syntheticum of formula ratio is added in ointment, mix homogeneously;
(4) vaseline 30 mass parts, lanoline 25 mass parts is gone to mix post-heating to 60 DEG C, make to melt completely, add the ointment of step (3) mix homogeneously, stir, add the sodium benzoate of 0.5 mass parts again, stir, make frost, after ultra-vioket radiation sterilizing, point packing.
Embodiment 3
A kind of external preparation for the treatment of mastopathy, it is characterized in that, the crude drug containing following mass parts: 20 parts, Flos Carthami, Sanguis Draxonis 9 parts, Rhizoma Chuanxiong 20 parts, Rhizoma Sparganii 12 parts, Herba Glechomae 30 parts, Myrrha 30 parts, Herba Agrimoniae 12 parts, Rhizoma Curcumae 25 parts, propolis 3 parts, 20 parts, Flos persicae, Rhizoma Acori Graminei 12 parts, Herba Taraxaci 25 parts, Borneolum Syntheticum 5 parts.
Preparation is with embodiment 2.
The present invention treats the using method of external preparation for mammary gland disease: through skin test without after allergy, and embrocating ointment of the present invention or cream 2 ~ 3 times every day in affected part, 14 days is a course for the treatment of.General two the course for the treatment of symptom alleviate to some extent or fully recover.
Clinical treatment case
Case 1: Huan Zhenv, 30 years old, finds enclosed mass in breast, distending pain of the breast on inspection, is cyclomastopathy through molybdenum target photographic diagnostics.Use the cream of embodiment 2 to embrocate breast, every day 3 times, adhere to further consultation after 30 days, mammary swelling disappears, and nodule in the breast limbers up, and does not find toxic and side effects.
Case 2: Huan Zhenv, 36 years old, gave birth to a son, breast feeding 12 months, after ablactation, mammary gland started atrophy, sagging, can touch a small amount of mammary gland.Use the cream of embodiment 2 to embrocate breast, every day 2 times, adhere to that 30 days rear udder attachments start to swell, without pain.After adhering to 60 days, breast obviously becomes full, without pain, does not also find toxic and side effects.
Case 3: Huan Zhenv, 25 years old, 10 days little puerperal distending pain of the breast, hypogalactia, galactorrhea, is defined as acute mastitis after diagnosing.Use the ointment of embodiment 1 after 15 days distending pain have and slow down, continue use 20 days transference cures, follow up a case by regular visits to acute mastitis and heal.
Case 4: patient female 40 years old, both sides distending pain of the breast, finds lump on inspection, menstrual period lower abdominal distention pain.Be diagnosed as cyclomastopathy.Use the ointment of embodiment 1 not have clear improvement after 10 days, but adhere to that use is after 30 days, distending pain of the breast obviously alleviates.Continue use 2 months, all transference cures, further consultation is determined to fully recover.Follow up a case by regular visits to without recurrence.
Case 5: patient female 38 years old, the unexpected red and swollen heat pain of right breast, mammary swelling unbearably.Be acute mastitis after diagnosing, use the cream of embodiment 2 to embrocate breast, use after 15 days, red and swollen elimination, continue use after 15 days, transference cure, spiritual amelioration, further consultation confirms to fully recover, and does not have toxic and side effects.
Above clinical practice example shows, treatment external preparation for mammary gland disease of the present invention has obvious therapeutical effect for mastopathy such as cyclomastopathy, acute mastitis, mastatrophy, cyclomastopathy, mastitis.And short treating period, instant effect, easily to consolidate, use safety, to have no side effect.
Claims (6)
1. treat the external preparation of mastopathy for one kind, it is characterized in that, be made up of the crude drug of following mass parts: 19 ~ 20 parts, Flos Carthami, Sanguis Draxonis 5 ~ 9 parts, Rhizoma Chuanxiong 10 ~ 20 parts, Rhizoma Sparganii 8 ~ 12 parts, Herba Glechomae 20 ~ 30 parts, Myrrha 20 ~ 30 parts, Herba Agrimoniae 8 ~ 12 parts, Rhizoma Curcumae 15 ~ 25 parts, propolis 1 ~ 3 part, 10 ~ 20 parts, Flos persicae, Rhizoma Acori Graminei 8 ~ 12 parts, Herba Taraxaci 15 ~ 25 parts, Borneolum Syntheticum 1 ~ 5 part.
2. treat the external preparation of mastopathy for one kind, it is characterized in that, be made up of the crude drug of following mass parts: 15 parts, Flos Carthami, Sanguis Draxonis 7 parts, Rhizoma Chuanxiong 15 parts, Rhizoma Sparganii 10 parts, Herba Glechomae 25 parts, Myrrha 25 parts, Herba Agrimoniae 10 parts, Rhizoma Curcumae 20 parts, propolis 2 parts, 15 parts, Flos persicae, Rhizoma Acori Graminei 10 parts, Herba Taraxaci 20 parts, Borneolum Syntheticum 3 parts.
3. external preparation according to claim 1 and 2, is characterized in that, also containing pharmaceutically acceptable adjuvant or carrier in described preparation.
4. external preparation according to claim 1 and 2, is characterized in that, described preparation is frost, ointment, emulsion or emplastrum.
5. a preparation method for external preparation as claimed in claim 1 or 2, comprises the steps:
(1) Flos Carthami, Sanguis Draxonis, Rhizoma Chuanxiong, Rhizoma Sparganii, Herba Glechomae, Myrrha, Herba Agrimoniae, Rhizoma Curcumae, Flos persicae, Rhizoma Acori Graminei, Herba Taraxaci is taken by formula, after Mechanical Crushing, add 2 ~ 5 times of volume 60% ~ 85% ethanol water reflux, extract, 1 ~ 3 time, each 1 ~ 2 hour;
(2) merge extractive liquid, decompression recycling ethanol is extremely without alcohol taste, and filter, discard filtering residue, released liquor, medicinal liquid concentrate under reduced pressure at low temperature obtains ointment;
(3) add propolis, the Borneolum Syntheticum of formula ratio in ointment, mix homogeneously, then add pharmaceutically acceptable carrier or adjuvant, be prepared into exterior-applied formulation.
6. preparation method according to claim 5, is characterized in that, described exterior-applied formulation comprises: frost, ointment, emulsion, emplastrum.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310140333.XA CN103239675B (en) | 2013-04-22 | 2013-04-22 | External preparation for treating breast diseases |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310140333.XA CN103239675B (en) | 2013-04-22 | 2013-04-22 | External preparation for treating breast diseases |
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| CN103239675A CN103239675A (en) | 2013-08-14 |
| CN103239675B true CN103239675B (en) | 2015-03-25 |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877431B (en) * | 2014-04-22 | 2016-03-23 | 杨明 | A kind of pharmaceutical composition for the treatment of chronic mastitis |
| CN104173924A (en) * | 2014-08-08 | 2014-12-03 | 王忠亮 | Medicine composition for treating plasma cell mastitis |
| CN104436012B (en) * | 2014-10-28 | 2018-02-16 | 王铁创 | A kind of External-applicationtraditional traditional Chinese medicinal for being used to treat mastitis |
| CN104940799A (en) * | 2014-12-30 | 2015-09-30 | 杨丛刚 | Externally applied drug for treating breast diseases and preparation method thereof |
| CN105380982A (en) * | 2015-11-17 | 2016-03-09 | 刘国灿 | Traditional Chinese medicine composition for treating breast diseases and preparation method thereof |
| CN105853873A (en) * | 2016-06-13 | 2016-08-17 | 郭洪赈 | External preparation for treating breast disease and preparation method thereof |
| CN108686079A (en) * | 2018-08-16 | 2018-10-23 | 佛山市新拓康医药科技有限公司 | A kind of Chinese medicine composition for treating wound, diabetes and exanthemv |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101224291B (en) * | 2008-01-07 | 2010-10-13 | 李显成 | Plaster for treating breast nodules and preparing method thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101224291B (en) * | 2008-01-07 | 2010-10-13 | 李显成 | Plaster for treating breast nodules and preparing method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 中药经皮给药治疗乳腺增生病的研究述略;宋爱莉等;《中医药学刊》;20060428;第24卷(第04期);594-596 * |
| 乳腺纤维腺瘤并存乳腺增生病配合中药治疗的临床研究;朱振庆等;《中国实用医药》;20090120;第4卷(第02期);111-112 * |
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