CN1099625A

CN1099625A - Medicine for enterelceosis

Info

Publication number: CN1099625A
Application number: CN 93111677
Authority: CN
Inventors: 王桂枝
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-08-30
Filing date: 1993-08-30
Publication date: 1995-03-08

Abstract

The content range of the medicinal ingredients (by weight percentage) is as follows: pilose asiabell 10-50%, root of membranous milk vetch 10-50%, tuber of hyacinth bletilla 10-50%, pseudo ginseng 0.5-15%, poria 5-40%, licorice root 3-40%, bark of Chinese cassia tree, 0.1-15% and myrobalan 3-30%. Said medicine can be made into capsule, powder, oral liquid and medicine to ber taken by mixing boiling water. The advantages are safety operation, without toxic side effects, extensively medicinal resources, stable quality of preparation and capable of making the patient be on the mend or even restorative for such diseases as ulcerative colitis, mucosal hemorrhage erosion and alcus of intestine, the total effective rate is 98%.

Description

Medicine for enterelceosis

The invention belongs to the medicinal preparation technical field, is a kind of medicine medicine for enterelceosis for the treatment of ulcerative colitis.

Ulcerative colitis at present, doctor trained in Western medicine all thinks the persistent ailment of refractory, now Western medicine adopts adrenal cortex hormones drug more both at home and abroad, as sulfasalazine, azathioprine, disodium cromoglycate, these medicines belong to immunosuppressant and prostaglandin synthesis inhibitors more, especially use more general with sulfasalazine, but these poisonous side effect of medicine are many, cause allergic reaction and serious toxic and side effects such as hepatic and renal function injure, occur erythra and heavier gastrointestinal stimulation symptom after taking medicine.The report that many employing medicine enema treatment primary disease were arranged in recent years, but since use inconvenient, in addition medicine difficulty reach disease institute, curative effect is satisfied not to the utmost, also has Chinese medicine preparation colon peaceful at present, but invalid to ulcerative colitis.

The objective of the invention is to provide a kind of having no side effect, and taking convenience is to eutherapeutic Chinese medicine medicine for enterelceosis of ulcerative colitis and manufacture method.

The objective of the invention is to realize with the following methods.The medicine components of medicine for enterelceosis of the present invention comprises Radix Codonopsis, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Notoginseng, Poria, Radix Glycyrrhizae, Cortex Cinnamomi, Fructus Chebulae, and the content range of used medicine components is: Radix Codonopsis 10-50%, Radix Astragali 10-50%, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-50%, Radix Notoginseng 0.5-15%, Poria 5-40%, Radix Glycyrrhizae 3-40%, Cortex Cinnamomi 0.1-15%, Fructus Chebulae 3-30%(are by weight percentage).To be the inventor develop through a large amount of clinical observations and the screening operation that reached more than 10 year this medicine, through pharmacodynamics, toxicology and systematic studys such as medicine stability test and quality standard, prove that this medical instrument has the enterokinesia that suppresses hyperfunction, the phagocytic function that strengthens monokaryon-macrophage, improve the tolerance to cold of " insufficiency of the spleen " mice, and body cell and humoral immune function had optimum dual regulation, this medicine is safe in utilization, have no side effect, and crude drug source is extensive.By row colonoscope check and inspection before and after patient's medication,, due to intestine erosion and ulcer hemorrhage to patients of ulcerative colitis, intestinal mucosa makes it to be clearly better until disappearance, and total effective rate is 98%.The Radix Codonopsis nature and flavor are sweet flat in ingredient of the present invention, power can the spleen reinforcing nourishing the stomach, spleen invigorating and not dry, grow stomach-Yin and wet, inspire gas in clear sun, the vibration, and do not have dry fraud just.The Radix Astragali is sweet in flavor and warm in property, can tonification in soil, replenishing vital QI with drugs of warm nature taste, can disappear five skin ulcer cellulitis of Radix Glycyrrhizae.Cortex Cinnamomi sweet in the mouth, extremely hot in nature, can promoting blood circulation, unclog and readjust deficiency, a surname leads hundred medicines.Poria is flat, sweet in the mouth, light, light energy eliminating dampness and diuresis, and the invigorating the spleen to arrest diarrhea of sweet energy is ginseng, stilbene, careless invigorating the spleen and benefiting QI, the open circuit of cleaning the street.Radix Notoginseng sweet and slightly bitter taste, warm in nature, can stop blooding, loose blood, analgesic therapy.Pseudobulbus Bletillae (Rhizoma Bletillae) property is puckery and receive, the gas of autumn, can go into the lung hemostasis, granulation promoting is held back and controlled skin ulcer.Fructus Chebulae, bitter in the mouth acid, property are put down, and can astringe the lung by astringing intestine to stop diarrhea, simmer with the solid intestinal of the kidney warming.This medicine is got Radix Codonopsis, the Radix Astragali, Radix Notoginseng three is distinguished the flavor of is monarch, invigorating the spleen and replenishing QI, promoting tissue regeneration by removing blood stasis, the source of the day after tomorrow of shaking, get Cortex Cinnamomi, Radix Glycyrrhizae, Poria three flavors and be minister, get the Pseudobulbus Bletillae (Rhizoma Bletillae) and be assistant, healing up sore and relieving pain simply, the Fructus Chebulae use for making, can help Radix Notoginseng, Radix Codonopsis, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae) directly to go into disease institute solid and gas astringing intestine to stop diarrhea, the convergence open sore part.Therefore the merit of the useful temperature sun of this medical instrument, promoting tissue regeneration by removing blood stasis, invigorating spleen to remove dampness, astringing QI astringing intestine to stop diarrhea has specially good effect to treating the difficult only difficult chronic ulcerative colitis that heals.

Medicine for enterelceosis of the present invention may be made in capsule, powder, electuary, oral liquid etc. according to the needs on the different patient treatments.

The manufacture method of medicine for enterelceosis of the present invention is that 10-50% Radix Codonopsis, the 10-50% Radix Astragali, the 10-50% Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5-15% Radix Notoginseng, 5-40% Poria, 3-40% Radix Glycyrrhizae, 0.1-15% Cortex Cinnamomi, 3-30% Fructus Chebulae's (by weight percentage) are taken by weighing respectively, Radix Codonopsis, the Radix Astragali, Fructus Chebulae, Poria, Radix Glycyrrhizae are added decocting juice make extractum, again the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Notoginseng, Cortex Cinnamomi are pulverized in the powdery adding extractum, graininess is dried in processing then, and adding is made the required additives of various dosage forms, additive, substrate, made various dosage forms again.Top processing is dried into during granular medicine incapsulates, make capsule.Particle grinding after perhaps will drying sieves, and makes it become fine powdered, makes powder, perhaps Radix Notoginseng, Cortex Cinnamomi is pulverized to adding an amount of soluble starch or sugar again after in the powdery adding extractum, stirring and dry into fine grained, make electuary.This medicine also can be made into oral liquid, be about to 10-50% Radix Codonopsis, the 10-50% Radix Astragali, the 10-50% Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5-15% Radix Notoginseng, 5-40% Poria, 3-40% Radix Glycyrrhizae, 0.1-15% Cortex Cinnamomi, 3-30% Fructus Chebulae's (by weight percentage) and take by weighing respectively, add decocting juice, filter, add an amount of antiseptic, stirring, cooling, filtration, fill, sterilization and promptly make oral liquid.

Be embodiments of the invention below:

Take by weighing 16.6% Radix Codonopsis, 22.1% Radix Astragali, 22% Pseudobulbus Bletillae (Rhizoma Bletillae), 3.3% Radix Notoginseng, 11% Poria, 6.6% Radix Glycyrrhizae, 1.7% Cortex Cinnamomi, 16.7% Fructus Chebulae (by weight percentage), earlier Radix Codonopsis, the Radix Astragali, Poria, Radix Glycyrrhizae, Fructus Chebulae are added decocting juice and make extractum, then the Pseudobulbus Bletillae (Rhizoma Bletillae), Cortex Cinnamomi, Radix Notoginseng powder being broken into powder adds in the extractum, after drying, processing makes granule, encapsulated, make the enterelceosis curing capsule.Using method, 3-5 grain, 2-3 time on the one.By 43 examples are diagnosed as after patients of ulcerative colitis carries out treatment in 3 months through romanoscope or second shape fibercolonscopy, per rectum spectroscopy, 40 routine inflammatory lesions or curing ulcer erosion disease disappear, 2 routine produce effects, it is invalid that 1 example was checked after March, but check is normal substantially after half a year.Visited 2 years, recidivist's 41 examples not, 2 examples are accidental, but the state of an illness is lighter, and total effective rate is 98.6%.

Claims

1, a kind of medicine medicine for enterelceosis for the treatment of ulcerative colitis is characterized in that medicine components comprises Radix Codonopsis, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Notoginseng, Poria, Radix Glycyrrhizae, Cortex Cinnamomi, Fructus Chebulae.

2, medicine for enterelceosis according to claim 1 is characterized in that the content range of used medicine components is: Radix Codonopsis 10-50%, Radix Astragali 10-50%, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-50%, Radix Notoginseng 0.5-15%, Poria 5-40%, Radix Glycyrrhizae 3-40%, Cortex Cinnamomi 0.1-15%, Fructus Chebulae 3-30%(are by weight percentage).

3, medicine for enterelceosis according to claim 1 and 2 is characterized in that may be made in capsule, powder, electuary, oral liquid.

4, a kind of manufacture method for the treatment of the medicine for enterelceosis of ulcerative colitis, 10-50% Radix Codonopsis, the 10-50% Radix Astragali, the 10-50% Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5-15% Radix Notoginseng, 5-40% Poria, 3-40% Radix Glycyrrhizae, 0.1-15% Cortex Cinnamomi, 3-30% Fructus Chebulae's (by weight percentage) are taken by weighing respectively, Radix Codonopsis, the Radix Astragali, Fructus Chebulae, Poria, Radix Glycyrrhizae are added decocting juice make extractum, again the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Notoginseng, Cortex Cinnamomi are pulverized in the powdery adding extractum, graininess is dried in processing then, and adding is made the required additives of various dosage forms, additive, substrate, made various dosage forms again.

5, medicine for enterelceosis according to claim 4, the graininess medicine after it is characterized in that processing dried incapsulates, and makes capsule.

6, medicine for enterelceosis according to claim 4 is characterized in that the particle grinding after drying is sieved, and makes it become fine powdered, makes powder.

7, medicine for enterelceosis according to claim 4 is characterized in that Radix Notoginseng, Cortex Cinnamomi pulverizing are added an amount of soluble starch or sugar again after in the powdery adding extractum, stirs and dries into fine grained, makes electuary.

8, a kind of manufacture method for the treatment of the medicine for enterelceosis of ulcerative colitis, 10-50% Radix Codonopsis, the 10-50% Radix Astragali, the 10-50% Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5-15% Radix Notoginseng, 5-40% Poria, 3-40% Radix Glycyrrhizae, 0.1-15% Cortex Cinnamomi, 3-30% Fructus Chebulae's (by weight percentage) are taken by weighing respectively, add decocting juice, filter, add an amount of antiseptic, stir evenly, cool off, filtration, fill, sterilization promptly make oral liquid.