CN102488751B - Chinese medicinal preparation for treating infantile diarrhea - Google Patents
Chinese medicinal preparation for treating infantile diarrhea Download PDFInfo
- Publication number
- CN102488751B CN102488751B CN 201110431466 CN201110431466A CN102488751B CN 102488751 B CN102488751 B CN 102488751B CN 201110431466 CN201110431466 CN 201110431466 CN 201110431466 A CN201110431466 A CN 201110431466A CN 102488751 B CN102488751 B CN 102488751B
- Authority
- CN
- China
- Prior art keywords
- parts
- preparation
- infantile diarrhea
- chinese medicinal
- medicinal preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 50
- 208000019637 Infantile Diarrhea Diseases 0.000 title claims abstract description 31
- 239000003814 drug Substances 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000002552 dosage form Substances 0.000 claims abstract description 6
- 229940079593 drug Drugs 0.000 claims description 14
- 210000000582 semen Anatomy 0.000 claims description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 11
- 239000008187 granular material Substances 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 229920001353 Dextrin Polymers 0.000 claims description 8
- 239000004375 Dextrin Substances 0.000 claims description 8
- 235000019425 dextrin Nutrition 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 10
- 230000003203 everyday effect Effects 0.000 abstract description 5
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 241000196324 Embryophyta Species 0.000 abstract description 2
- 238000002791 soaking Methods 0.000 abstract 3
- 240000004510 Agastache rugosa Species 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 229930184510 Mallotus Natural products 0.000 abstract 1
- 241001060384 Mallotus <angiosperm> Species 0.000 abstract 1
- 235000003805 Musa ABB Group Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 235000015266 Plantago major Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 206010012735 Diarrhoea Diseases 0.000 description 12
- 230000013872 defecation Effects 0.000 description 9
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 102000002322 Egg Proteins Human genes 0.000 description 2
- 108010000912 Egg Proteins Proteins 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 229940126701 oral medication Drugs 0.000 description 2
- 210000004681 ovum Anatomy 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 235000014347 soups Nutrition 0.000 description 2
- 206010012742 Diarrhoea infectious Diseases 0.000 description 1
- 241000219000 Populus Species 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010040830 Skin discomfort Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 208000035850 clinical syndrome Diseases 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese medicinal preparation for treating infantile diarrhea. The Chinese medicinal preparation is prepared from the following bulk pharmaceuticals in parts by weight: 5-50 parts of Japanese mallotus bark, 5-10 parts of plantain seed, 5-20 parts of wrinkled gianthyssop herb, 5-20 parts of large-head atractylodes rhizome and 5-20 parts of indian buead, and can comprise the following bulk pharmaceuticals in parts by weight: 5-20 parts of dried orange peel and 5-20 parts of liquoric root. The preparation method comprises the following steps of: mixing the bulk pharmaceuticals; adding water for soaking; decocting with soft fire for 20-40 minutes; and adding pharmaceutically-acceptable auxiliary materials to prepare a conventional dosage form. During treatment, one dose of the Chinese medicinal preparation for treating infantile diarrhea is treated with 1,000-1,500 ml of boiled water, and is used for soaking feet till the temperature is proper for 3-15 minutes. For an infant suffering from severe infantile diarrhea, the Chinese medicinal preparation can be used for washing lower legs, so that an effect is enhanced. The Chinese medicinal preparation is appliedtwice every day, one dose every time; and infantile diarrhea can be cured generally within 2-3 times. A formula provided by the invention is a pure plant formula, has no side effect, is convenient and painless when used for soaking feet, and can be used for quickly treating infantile diarrhea.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of infantile diarrhea.
Background technology
Infantile diarrhea is divided into infectious and non-infectious two classes according to the cause of disease, is by many cause of diseases, the multifactor one group of clinical syndrome based on diarrhoea that causes.Age of onset is many below 2 years old, accounts for 50% with interior person in 1 years old.Every year is died from the child of diarrhoea up to 5,000,000～1,800 ten thousand in the whole world.In China, infantile diarrhea is the 2nd commonly encountered diseases, the frequently-occurring disease that is only second to respiratory tract infection.
At present, the method for the treatment of infantile diarrhea has transfusion, oral drugs, diarrhoea subsides, coloclysis etc., but all has following defective: can't satisfy simultaneously fast effectively, make things convenient for no pain, curative effect such as have no side effect, such as: upward outpatient service is infused: the expense height, and of long duration; Oral drugs: the child is difficult to swallow; Coloclysis: cause suffering to health, diarrhoea is pasted: take effect slowly, easily cause the skin discomfort.
In the prior art, adopt or be combined with the external-use lotion mode and treat the medicine of infantile diarrhea and have following several:
(1) Herba humuli scandentis egg: Herba humuli scandentis 30g, 1 piece in egg.Usage: ripe with boiling to egg with Herba humuli scandentis and egg, the food egg is with the medicine juice foot bath.
(2) Herba Plantaginis egg: Herba Plantaginis 30g, 1 piece in egg.Usage: boil together with Herba Plantaginis and egg, ripe to egg.The food egg is with the medicine juice foot bath.
(3) Semen phaseoli radiati powder Ovum Gallus domesticus album: Semen phaseoli radiati powder 9g, 1 piece of Ovum Gallus domesticus album.Usage: being in harmonious proportion altogether is cake, and the habitual vomiter is affixed on fontanel, and diarrhoea person is affixed on the sufficient heart, effectively.
But these several modes are folk prescription, and curative effect is unfixing, and is effective to the infantile diarrhea patient who has, invalid to most infantile diarrhea patient.Therefore, be badly in need of a kind of curative effect fixing to the effective Chinese medicine preparation of most of infantile diarrhea patients.
Summary of the invention
At above-mentioned prior art, the invention provides a kind of Chinese medicine preparation for the treatment of infantile diarrhea.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine preparation for the treatment of infantile diarrhea is by comprising that following bulk drugs makes: 5～50 parts of Cortex malloti japonici, 5～10 parts of Semen Plantaginiss, 5～20 parts of Herba Pogostemoniss, 5～20 parts of the Rhizoma Atractylodis Macrocephalaes, 5～20 parts in Poria.
The Chinese medicine preparation of described treatment infantile diarrhea also comprises following bulk drugs: 5～20 parts of Pericarpium Citri Reticulataes, 5～20 parts in Radix Glycyrrhizae.
Preferably, made by following crude drug: Cortex malloti japonici 30g, Semen Plantaginis 8g, Herba Pogostemonis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 10g.
During preparation, get each crude drug, mix, add water to submerge, slow fire boils 20～40min namely.Perhaps, further, add acceptable accessories and make regular dosage form.
Described acceptable accessories is dextrin, and the dosage form of making is granule.
In addition, also can use steam distillation to get extract, make regular dosage form then.
During treatment, get the Chinese medicine preparation (amount of above-mentioned preferred prescription is the amount of potion) of the treatment infantile diarrhea of potion, wash open with 1000～1500ml boiling water, after treating that temperature is suitable, foot bath 3～15 minutes, with 5 minutes be the best, severe patient can suitably be coated with washes the shank position with reinforced effects.Every day twice, each potion, general treatment can be cured for 2～3 times.
Prescription of the present invention is pure plant formula, has no side effect, and foot bath uses, and convenient, no pain can be treated infantile diarrhea fast.Prescription of the present invention is treated example surplus the infant 500 altogether, cure 480 surplus example, generally all is that treatment is cured for 2～3 times, as seen, it has advantages such as cure rate height, curative effect be fast.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment.
The Chinese medicine preparation of embodiment 1 preparation treatment infantile diarrhea
Prescription is: Cortex malloti japonici 30g, Semen Plantaginis 8g, Herba Pogostemonis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 10g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 30min, adds an amount of dextrin then, makes granule, namely.
During treatment, get the above-mentioned granule of potion, wash open with 1000～1500ml boiling water, treat that temperature is suitable after, foot bath 3～15 minutes, with 5 minutes be the best, severe patient can suitably be coated with washes the shank position with reinforced effects.Every day twice, each potion, general treatment can be cured for 2～3 times.
The Chinese medicine preparation of embodiment 2 preparation treatment infantile diarrheas
Prescription is: Cortex malloti japonici 50g, Semen Plantaginis 5g, Herba Pogostemonis 20g, Rhizoma Atractylodis Macrocephalae 5g, Poria 20g, Pericarpium Citri Reticulatae 5g, Radix Glycyrrhizae 20g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 20min, adds an amount of dextrin then, makes granule, namely.
The Chinese medicine preparation of embodiment 3 preparation treatment infantile diarrheas
Prescription is: Cortex malloti japonici 5g, Semen Plantaginis 10g, Herba Pogostemonis 5g, Rhizoma Atractylodis Macrocephalae 20g, Poria 5g, Pericarpium Citri Reticulatae 20g, Radix Glycyrrhizae 5g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 40min, adds an amount of dextrin then, makes granule, namely.
The Chinese medicine preparation of embodiment 4 preparation treatment infantile diarrheas
Prescription is: Cortex malloti japonici 20g, Semen Plantaginis 6g, Herba Pogostemonis 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 10g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 30min, adds an amount of dextrin then, makes granule, namely.
The Chinese medicine preparation of embodiment 5 preparation treatment infantile diarrheas
Prescription is: Cortex malloti japonici 40g, Semen Plantaginis 9g, Herba Pogostemonis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Pericarpium Citri Reticulatae 15g, Radix Glycyrrhizae 15g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 40min, adds an amount of dextrin then, makes granule, namely.
The Chinese medicine preparation of embodiment 6 preparation treatment infantile diarrheas
Prescription is: Cortex malloti japonici 30g, Semen Plantaginis 7g, Herba Pogostemonis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 10g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 30min, namely.
During treatment, to be cooled to suitable temperature, directly foot bath.
The Chinese medicine preparation of embodiment 7 preparation treatment infantile diarrheas
Prescription is: Cortex malloti japonici 30g, Semen Plantaginis 8g, Herba Pogostemonis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g.
Preparation method is: get each crude drug, mix, add water to submerge, slow fire boils 30min, adds an amount of dextrin then, makes granule, namely.
Case
Case 1 patient: Mrs's Yang son, at six months ages, infuse because of fever winter, and transfusion back fever goes down, and begins diarrhoea, and defecation is thin, about every day 10 times.9 use prescriptions of the present invention in evening (embodiment 1 preparation) foot bath 5 minutes; About 10 of the next mornings, begin one time defecation, the stool retrogradation is cured.
Case 2 patients: Mr.'s Han son, at eight months ages, diarrhoea a couple of days, feces is completely mashed, every day 6～7 times, use prescription of the present invention (embodiment 1 preparation) treatment once after, recover normal.
Case 3 patients: Mr.'s Feng son, at four months ages, defecation is the egg style, and stink is not obvious, and defecation was 8～10 times in one day, used prescription of the present invention (embodiment 1 preparation) treatment once evening, namely recovered normal in second day.
Case 4 patients: poplar, at 13 months ages, weakness of the spleen and stomach is often suffered from diarrhoea, defecation was about 10 times in one day, defecation is egg soup sample, use prescription of the present invention (embodiment 2 preparation) treatment three times after, begin to recover normal.
Case 5 patients: Korea Spro so-and-so, at 6 months ages, diarrhoea was 10～12 times in one day, it is rancid defecate, with having no appetite, use prescription of the present invention (embodiment 2 preparation) treatment secondary after, recover normally.
Case 6 patients: Zhu, 4 months ages, catch cold and catch a cold, diarrhoea was 8～9 times in one day, the stool egg soup sample, use prescription of the present invention (embodiment 3 preparation) treatment once after, recover normal.
Case 7 patients: little beautiful, at 7 months ages, chronic diarrhea is not healed, the time light when heavy, it is thin heavy to defecate, and is the indigestion shape, use prescription of the present invention (embodiment 3 preparations) treatment three times after, begin to recover normal.
Case 8 patients: Mrs's Dong daughter, at 6 months ages, defecation was 14 times in one day, it is rancid to defecate, the water gruel shape, use prescription of the present invention (embodiment 6 preparation) treatment once after, defecation obviously reduces, defecation was 6 times in one day, continue treatment three times after, recover normal.
By above-mentioned case and practice as can be known, this prescription has extraordinary therapeutic effect to infantile diarrhea, noninfectious diarrhea especially, and effect is very obvious, to infectious diarrhea, certain effect is arranged, and is invalid to dysentery.
Claims (5)
1. the Chinese medicine preparation of a foot bath treatment infantile diarrhea is characterized in that: made by following bulk drugs: 5～50 parts of Cortex malloti japonici, 5～10 parts of Semen Plantaginiss, 5～20 parts of Herba Pogostemoniss, 5～20 parts of the Rhizoma Atractylodis Macrocephalaes, 5～20 parts in Poria, 5～20 parts of Pericarpium Citri Reticulataes, 5～20 parts in Radix Glycyrrhizae.
2. the Chinese medicine preparation of a kind of foot bath treatment infantile diarrhea according to claim 1 is characterized in that: made by following crude drug: Cortex malloti japonici 30g, Semen Plantaginis 8g, Herba Pogostemonis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 10g.
3. the preparation method of the Chinese medicine preparation of each described a kind of foot bath treatment infantile diarrhea in the claim 1～2, it is characterized in that: get each crude drug, mix, add water to submerge, slow fire boils 20～40min namely.
4. preparation method according to claim 3 is characterized in that: after boiling, add acceptable accessories and make regular dosage form.
5. preparation method according to claim 4, it is characterized in that: described acceptable accessories is dextrin, the dosage form of making is granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110431466 CN102488751B (en) | 2011-12-21 | 2011-12-21 | Chinese medicinal preparation for treating infantile diarrhea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110431466 CN102488751B (en) | 2011-12-21 | 2011-12-21 | Chinese medicinal preparation for treating infantile diarrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102488751A CN102488751A (en) | 2012-06-13 |
| CN102488751B true CN102488751B (en) | 2013-10-09 |
Family
ID=46180652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110431466 Expired - Fee Related CN102488751B (en) | 2011-12-21 | 2011-12-21 | Chinese medicinal preparation for treating infantile diarrhea |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102488751B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697934A (en) * | 2012-06-25 | 2012-10-03 | 陈慧婷 | Golden cypress traditional Chinese medicine preparation for treating diarrhea and preparation method for preparation |
| CN104436142B (en) * | 2014-12-19 | 2017-09-29 | 何子双 | A kind of Chinese medicine composition for treating pig epidemic diarrhea |
| CN104997993A (en) * | 2015-07-09 | 2015-10-28 | 张鑫 | Traditional Chinese medicinal preparation for treating colon infection diarrhoea |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133724A (en) * | 1995-12-06 | 1996-10-23 | 李修身 | Antidiarrheal oral liquid and its preparing process |
| CN1435202A (en) * | 2002-01-27 | 2003-08-13 | 武水庆 | Medicine for treating child diarrhea |
| JP3547782B2 (en) * | 1993-12-28 | 2004-07-28 | ロート製薬株式会社 | Anti-Helicobacter pylori activator |
| KR20110059408A (en) * | 2009-11-27 | 2011-06-02 | 경상북도 (관련부서:경상북도축산기술연구소장) | A process for producing feedstuff additives comprising natural herbs and having a preventing activity of calf's diarrhea |
-
2011
- 2011-12-21 CN CN 201110431466 patent/CN102488751B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3547782B2 (en) * | 1993-12-28 | 2004-07-28 | ロート製薬株式会社 | Anti-Helicobacter pylori activator |
| CN1133724A (en) * | 1995-12-06 | 1996-10-23 | 李修身 | Antidiarrheal oral liquid and its preparing process |
| CN1435202A (en) * | 2002-01-27 | 2003-08-13 | 武水庆 | Medicine for treating child diarrhea |
| KR20110059408A (en) * | 2009-11-27 | 2011-06-02 | 경상북도 (관련부서:경상북도축산기술연구소장) | A process for producing feedstuff additives comprising natural herbs and having a preventing activity of calf's diarrhea |
Non-Patent Citations (4)
| Title |
|---|
| 健脾利湿止泻汤治疗婴幼儿秋季腹泻123例;周康宁;《中国基层医药》;20000229;第7卷(第1期);第36页左栏第1.2节第1-5行， * |
| 周康宁.健脾利湿止泻汤治疗婴幼儿秋季腹泻123例.《中国基层医药》.2000,第7卷(第1期),第36页左栏第1.2节第1-5行，. |
| 泄泻的几种简易外治法;王桂芬;《双足与保健》;20061231(第3期);第16页右栏最后2行至第17页左栏第1-3行 * |
| 王桂芬.泄泻的几种简易外治法.《双足与保健》.2006,(第3期),第16页右栏最后2行至第17页左栏第1-3行. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102488751A (en) | 2012-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102028900A (en) | Traditional Chinese medicine for treating metabolic syndrome and preparation method thereof | |
| CN102166278B (en) | Chinese medicinal composition for treating pediatric rheumatoid arthritis and preparation method thereof | |
| CN104623018A (en) | Novel traditional Chinese medicine lotion for removing jaundice of newborn and preparation method of novel traditional Chinese medicine lotion | |
| CN104013756B (en) | A kind of Chinese medicine composition for preventing and treating diarrhoea and application thereof | |
| CN103301267B (en) | Traditional Chinese medicine composition for treating hypertension and/or atherosclerosis and application thereof | |
| CN102940785B (en) | Traditional Chinese medicine composition for treating vertigo | |
| CN102488751B (en) | Chinese medicinal preparation for treating infantile diarrhea | |
| CN103933346A (en) | Blood-glucose-reducing composition and preparation method thereof | |
| CN102727779A (en) | Pharmaceutical composition for treating ovarian cysts and preparation method thereof | |
| CN101095768A (en) | Chinese traditional medicine capsule for treating primary hypertension for persons in middle and old age | |
| CN102133288B (en) | Chinese herbal preparation for curing angina | |
| CN103446575B (en) | Medicine for treating gout | |
| CN101912596A (en) | Medicament for treating allergic rhinitis and preparation method thereof | |
| CN100515462C (en) | Chinese medicine for treating cardiovascular and cerebrovascular trrombus and preparing method | |
| CN104524479B (en) | A kind of Chinese medicine composition for treating premenstrual syndrome and preparation method thereof | |
| CN103585495B (en) | Capsule for treating diabetic kidney damage | |
| CN103041233A (en) | Pharmaceutical composition for treating infantile diarrhea and preparation method thereof | |
| CN103301368B (en) | Medicament for treating hyperactivity | |
| CN105833055A (en) | Traditional Chinese medicine composition for treating hypertension, hyperlipidemia and hyperglycemia and preparing method and application thereof | |
| CN104758578A (en) | Traditional Chinese medicine composition for treating palpitation | |
| CN103239626A (en) | Medicament formula for healthcare and treatment of middle-aged and elderly people | |
| CN108743885A (en) | A kind of Chinese medicine and preparation method thereof for treating Diabetic Macrovascular Complications | |
| CN103495108A (en) | Medicine for treating chronic hypotension and preparation method for medicine | |
| CN103520538B (en) | A kind ofly treat the pharmaceutical composition that diabetes cause kidney damage | |
| CN102688373A (en) | Medicine for treating astriction and preparation method for medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131009 |