CN109953938A - Skin regulates and controls water and preparation method thereof - Google Patents

Skin regulates and controls water and preparation method thereof Download PDF

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Publication number
CN109953938A
CN109953938A CN201910282711.5A CN201910282711A CN109953938A CN 109953938 A CN109953938 A CN 109953938A CN 201910282711 A CN201910282711 A CN 201910282711A CN 109953938 A CN109953938 A CN 109953938A
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Prior art keywords
water
skin
essence
regulates
phase
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Chinese (zh)
Inventor
华子昂
朱美瑛
竹添
孙宁
王姣
张建
万君兴
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists

Abstract

The present invention relates to a kind of skins to regulate and control water, each component including following mass percent: moisturizer 0.01%-20%, emollient 0.01%-15%, surfactant 0.01%-15%, preservative 0.001%-5%, essence 0.01%-5%, acidic electrolytic water 60%-98%.The present invention also provides a kind of preparation methods of above-mentioned skin regulation water, and part moisturizer, emollient, surfactant, preservative, essence stirring and dissolving are formed phase 1 by (1);(2) part essence is added in acidic electrolytic water, forms phase 2;(3) moisturizer, emollient, surfactant, preservative, essence are added in acidic electrolytic water, form phase 3;(4) phase 1, phase 2 are added to phase 3, stirred evenly, adjust pH to 4.5-6.5 to get.Skin regulation water energy provided by the invention enough changes skin microcirculation, establishes the effective moisture retention structure of skin, promotes the metabolism of skin texture optimization and operation function, not only moisturizing, but also water conservation, and preparation process is simple, easy to use.

Description

Skin regulates and controls water and preparation method thereof
Technical field
The invention belongs to daily technical field of skin care, and in particular to a kind of skin regulation water and preparation method thereof.
Background technique
People have one-hundred-year history to the research of skin surface pH value.But it just causes people to the importance of skin in recent years Great attention.Research has shown that the pH value of skin surface is expression of the body biological action in epidermis, can also influence cutin shape At the cell even biological function of corium.In different growth and development stages, the pH value of skin surface has certain variation, but Acidity is still the pH value on normal adult's optimum skin surface.
The most important function of skin care item is to adjust skin physiology function, achievees the purpose that replenishing water and preserving moisture, anti-senility.Skin care The first step be face cleaning, since, in acidity, to reach net skin effect, mildy wash is generally in alkalinity under skin normal physiological condition Or it is neutral.And when skin ph increases, it is reduced with the activity of skin barrier function maturing relevant enzyme, the barrier function of skin Also it can reduce.Therefore, so that sensibiligen, chemical substance and microorganism is entered body and cause allergy, poisoning and infection.In addition, Under higher pH value condition, microorganism is also easy to produce and discharges anaphylactogen, and then generates inflammatory reaction.Also, skin neutral and Under alkaline condition, the activity of skin protein kinases increases, and the latter's degradation desmosome reduces the number of cuticula desmosome, angle The compactness and adhesion of matter layer are significantly reduced.Therefore skin pH adjusting should be carried out after face cleaning, rapidly goes to alkaline skin Acidity, to keep skin normal physiological function.
Chinese invention patent application (application number: the CN201710320407.6 applying date: 2017-04-27) discloses one kind Hydrogen-rich anion moisturizing facial mask, the facial mask can generate hydrogen-rich water, and sustained release anion prolongs for neutralizing acid-base scale of skin Slow cell ageing has positive effect.Skin microcirculation can be improved simultaneously, accelerate epithelium regeneration, promote cell metabolism.Have Bacteriostasis can be the excellent skin care product for preventing allergic dermatitis with wound healing.
Summary of the invention
It is in bad biological impact that is alkaline and its generating to solve skin after face cleaning, it is an object of the present invention to provide A kind of skin regulation water, skin regulation water energy enough change skin microcirculation, establish the effective moisture retention structure of skin, promote skin knot The metabolism of structure optimization and operation function, not only moisturizing, but also water conservation;It is a further object to provide a kind of above-mentioned skins Regulate and control the preparation method of water.
Skin provided by the invention regulates and controls water, each component including following mass percent: moisturizer 0.01%-20%, Emollient 0.01%-15%, surfactant 0.01%-15%, preservative 0.001%-5%, essence 0.01%-5% are acid Electrolysis water 60%-98%.
Preferably, each component including following mass percent: moisturizer 0.1%-15%, emollient 0.1%- 10%, surfactant 0.1%-15%, preservative 0.05%-4%, essence 0.05%-4%, acidic electrolytic water 65%- 95%.
In any of the above-described scheme preferably, each component including following mass percent: moisturizer 0.5%- 10%, emollient 0.5%-5%, surfactant 1%-10%, preservative 0.1%-3%, essence 0.05%-2%, it is acid Electrolysis water 75%-95%.
In any of the above-described scheme preferably, the moisturizer is glycerol, propylene glycol, trimethylglycine, neural acyl One of amine, super-fine pearl powder powder, hyaluronic acid, allantoin, Trenaxmine are a variety of.
In any of the above-described scheme preferably, the emollient be water-soluble lanolin, cocounut oil acid glyceride, sorbierite, One of pyrrolidones hydroxy acid sodium, hydrolecithin, shea butter, jojoba oil, dimethicone are a variety of.
In any of the above-described scheme preferably, the surfactant is water-soluble olive oil, anhydrous sorbitol tristearin One of acid esters, octadecyl glucose ester, polysorbate are a variety of.
In any of the above-described scheme preferably, the preservative is iodopropynyl butyl formate, benzoic acid, Buddhist nun Moor one of tortoise beetle ester, potassium sorbate, sodium benzoate or a variety of.
In any of the above-described scheme preferably, the essence is heliotropin, vanillic aldehyde, undecyl ketone, butyl butyrate, perfume (or spice) One of leaf-alcohol, irisone are a variety of.
In any of the above-described scheme preferably, the acidic electrolytic water is the pH4.5-6.5 of electrolyte machine preparation Water.
In any of the above-described scheme preferably, the skin regulates and controls water by mass percentage as shown in Table 1:
1 skin of table regulates and controls water composition preferred component and content
The present invention also provides a kind of preparation methods of above-mentioned skin regulation water, according to sequencing the following steps are included:
(1): moisturizer, emollient, surfactant, preservative and essence stirring and dissolving are formed into phase 1;
(2): essence being added in a small amount of acidic electrolytic water that temperature is 20 DEG C -50 DEG C, stir evenly, be cooled to room temperature Form phase 2;
(3): by moisturizer;, emollient, surfactant, preservative and essence, be added in acidic electrolytic water, stir It is formed uniformly phase 3;
(4): phase 1, phase 2 being added to phase 3, stirred evenly, pH to 4.5-6.5 is adjusted to get skin and regulates and controls water.
Regulation water of the present invention uses accurate replenishing water and preserving moisture formula, and acidity regulation water Cucumber Extract enzyme restores angle Matter layer compactness and adhesiveness can change skin microcirculation, establish the effective moisture retention structure of skin, promote skin texture optimization with The metabolism of operation function, not only moisturizing, but also water conservation, and preparation process is simple, it is easy to use.
Specific embodiment
In order to be further understood that summary of the invention of the invention, the present invention is elaborated below in conjunction with specific embodiment.
Embodiment one
It is 0.01%-20%, preferably 0.1%-15%, the moisturizing of more preferable 0.5%-10% by part mass percentage Agent;0.01%-15%, preferably 0.1%-10%, the emollient of more preferable 0.5%-5%;0.01%-10%, preferably 0.1- 15%, the surfactant of more preferable 1-10%;0.001%-5%, preferably 0.05-4%, the preservative of more preferable 0.1-3%; The essence stirring and dissolving of 0.01%-5%, preferably 0.05%-4%, more preferable 0.05-2% form phase 1;
It is 0.01%-5% by part mass percentage, the essence of preferably 0.05%-4%, more preferable 0.05%-2% add Entering to mass fraction is 60%-98%, preferably 65%-95%, more preferable 75%-95%, and temperature is 20 DEG C -50 DEG C a small amount of It in acidic electrolytic water, stirs evenly, is cooled to room temperature to form phase 2;
It is 0.01%-20%, preferably 0.1%-15%, the moisturizing of more preferable 0.5%-10% by residual mass percentage Agent;0.01%-15%, preferably 0.1%-10%, the emollient of more preferable 0.5%-5%;0.01%-10%, preferably 0.1- 15%, the surfactant of more preferable 1-10%;0.001%-5%, preferably 0.05-4%, the preservative of more preferable 0.1-3%; 0.01%-5%, preferably 0.05%-4%, the essence of more preferable 0.05-2%, being added to mass fraction is 60%-98%, preferably In the remaining acidic electrolytic water of 65%-95%, more preferable 75%-95%, stir evenly to form phase 3;
Phase 1, phase 2 are added to phase 3, stirred evenly, pH to 4.5-6.5 is adjusted, obtains skin regulation of the present invention Water.
Specific embodiment:
2 embodiment list of table
Regulate and control water to the improvement of skin, with skin tune as described in example 2 further to verify skin of the invention Control water is experimental group, certain brand smoothing toner is that control group carries out sense organ assessment and moisture content of skin measurement experiment:
Sensory test
Experimental subjects: 20-50 years old is randomly selected without skin injury, without allergy, without 60 people of skin patient as study subject;
Experimental method: cleaning skin takes the regulation water of appropriate experimental group to be uniformly applied to face, once in the morning and once at night, continuously Using 60 days, observes and experience using effect and record;Equal conditions reuse the progress of control group smoothing toner after deactivating 20 days Test.
Data statistics: questionnaire, statistical result are collected.
Moisture content of skin measurement
Experimental subjects: randomly select 20-50 years old without skin injury, without allergy, without 20 people of skin patient women, male 10 People, totally 30 people;And above-mentioned crowd is randomly divided into 2 groups, every group includes 10 people of women, 5 people of male.
Experimental facilities: DermaLab skin detection instrument;
Experimental method: two groups of people test in synchronization on the same day, respectively in " before use ", " use 1h ", " make With the water content of 3h ", " use 5h ", " using 7h " and " using 10h " detection face cheek region afterwards, each moment same position 3 records are detected, average value is chosen;
Data statistics: for statistical analysis using SPSS20.0 editions statistical softwares.
Statistical analysis
3 skin of table regulates and controls water using effect statistics
As shown in Table 3, the absorption, moisturizing of test group regulation water, skin lightening whitening effect are superior to control group smoothing toner, and gas Taste, texture are good, and evaluation is high, and nobody has allergic phenomena in investigation, and applicability is good.
4 moisture of skin of table measures (x ± s, n=3)
Note: same column difference lowercase indicates 0.05 level of signifiance.
As shown in Table 4,1 hour skin moisture content is most after use for of the invention skin regulation water and control group smoothing toner Height, and experimental group is apparently higher than control group, illustrates the initial moisturizing effect of regulation water of the present invention better than control group;Use rear 1- In 10 hours, experimental group and control group moisture of skin reduce increase with time, but each period water content of experimental group is above Control group illustrates skin regulation water moistening effect of the present invention better than control group.
In conclusion skin of the present invention regulates and controls water no matter from sensory effects or practical replenishing water and preserving moisture effect, more It is excellent.
It will be apparent to those skilled in the art that skin regulation water and preparation method thereof of the invention includes that aforementioned present invention is said The summary of the invention and specific embodiment part of bright book, as space is limited and to keep specification concise without constituting these combinations Each scheme describe one by one.All within the spirits and principles of the present invention, any modification, equivalent substitution, improvement and etc. done, It should be included within protection scope of the present invention.

Claims (10)

1. a kind of skin regulates and controls water, each component including following mass percent: moisturizer 0.01%-20%, emollient 0.01%-15%, surfactant 0.01%-15%, preservative 0.001%-5%, essence 0.01%-5%, acidic electrolytic water 60%-98%.
2. skin according to claim 1 regulates and controls water, which is characterized in that each component including following mass percent: protecting Humectant 0.1%-15%, emollient 0.1%-10%, surfactant 0.1%-15%, preservative 0.05%-4%, essence 0.05%-4%, acidic electrolytic water 65%-95%.
3. skin according to claim 2 regulates and controls water, which is characterized in that each component including following mass percent: protecting Humectant 0.5%-10%, emollient 0.5%-5%, surfactant 1%-10%, preservative 0.1%-3%, essence 0.05%- 2%, acidic electrolytic water 75%-95%.
4. skin according to claim 3 regulates and controls water, which is characterized in that the moisturizer is glycerol, propylene glycol, trimethyl One of glycine, ceramide, super-fine pearl powder powder, hyaluronic acid, allantoin, Trenaxmine are a variety of.
5. skin according to claim 3 regulates and controls water, which is characterized in that the emollient is water-soluble lanolin, coconut oil One of glyceride, sorbierite, pyrrolidones hydroxy acid sodium, hydrolecithin, shea butter, jojoba oil, dimethicone Or it is a variety of, the surfactant is water-soluble olive oil, Span60, octadecyl glucose ester, poly- sorb One of acid esters is a variety of.
6. skin according to claim 3 regulates and controls water, which is characterized in that the preservative is iodopropynyl formic acid One of butyl ester, benzoic acid, methylparaben, potassium sorbate, sodium benzoate are a variety of.
7. skin according to claim 3 regulates and controls water, which is characterized in that the essence is heliotropin, vanillic aldehyde, 11 One of ketone, butyl butyrate, geraniol, irisone are a variety of.
8. skin according to claim 3 regulates and controls water, which is characterized in that the acidic electrolytic water is the preparation of electrolyte machine The water of pH4.5-6.5.
9. skin according to claim 1 to 8 regulates and controls water, which is characterized in that including following mass percent Each component:
Moisturizer: glycerol 2%-15%, propylene glycol 0%-10%, trimethylglycine 0%-5%, ceramide 0%-2% surpass Fine pearl powder 0%--3%, hyaluronic acid 0%-2%, allantoin 0%-2%, Trenaxmine 0%-2%;
Emollient: water-soluble lanolin 0%-5%, cocounut oil acid glyceride 0%-5%, sorbierite 0%-2%, pyrrolidones hydroxy acid sodium 1%--5%, hydrolecithin 0%-5%, shea butter 0%-10%, jojoba oil 0%-10%, dimethicone 0%- 2%;
Surfactant: water-soluble olive oil 0%-5%, Span60 0%-5%, octadecyl glucose ester 0%-5%, polysorbate 0%-2%;
Preservative: iodopropynyl butyl formate 0.001%-2%, benzoic acid 0%-2%, methylparaben 0%-2%, Potassium sorbate 0%-2%, sodium benzoate 0%-2%;
Essence: heliotropin 0%-5%, vanillic aldehyde 0%-5%, undecyl ketone 0%-2%, butyl butyrate 0%-2%, geraniol 0%-2%, irisone 0%-2%;
The electrolyte water of pH4.5-6.5: 60%-98%.
10. a kind of preparation method of skin regulation water, according to sequencing the following steps are included:
(1): moisturizer, emollient, surfactant, preservative and essence stirring and dissolving are formed into phase 1;
(2): essence being added in a small amount of acidic electrolytic water that temperature is 20 DEG C -50 DEG C, stir evenly, be cooled to room temperature to be formed Phase 2;
(3): by moisturizer;, emollient, surfactant, preservative and essence, be added in acidic electrolytic water, stir evenly Form phase 3;
(4): phase 1, phase 2 being added to phase 3, stirred evenly, pH to 4.5-6.5 is adjusted to get skin and regulates and controls water.
CN201910282711.5A 2019-04-10 2019-04-10 Skin regulates and controls water and preparation method thereof Pending CN109953938A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1525844A (en) * 2001-06-01 2004-09-01 田中雅也 Acidic composition for external use and agent for accelerating infiltration of cosmetic preparation, hair-growing agent, and preparation for external use each containing the composition into skin or t
CN101966135A (en) * 2010-09-30 2011-02-09 江苏隆力奇生物科技股份有限公司 Toning lotion and preparation method thereof
CN102406578A (en) * 2011-09-27 2012-04-11 沈志荣 Silky bright-color smoothing toner composition and preparation method
CN107412257A (en) * 2017-08-17 2017-12-01 呼和浩特民族学院 A kind of milk cow nipple medicated bath agent and its preparation method and application
CN109077940A (en) * 2018-08-23 2018-12-25 山西纳安生物科技有限公司 A kind of beauty mask and preparation method thereof of electrolysis water preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1525844A (en) * 2001-06-01 2004-09-01 田中雅也 Acidic composition for external use and agent for accelerating infiltration of cosmetic preparation, hair-growing agent, and preparation for external use each containing the composition into skin or t
CN101966135A (en) * 2010-09-30 2011-02-09 江苏隆力奇生物科技股份有限公司 Toning lotion and preparation method thereof
CN102406578A (en) * 2011-09-27 2012-04-11 沈志荣 Silky bright-color smoothing toner composition and preparation method
CN107412257A (en) * 2017-08-17 2017-12-01 呼和浩特民族学院 A kind of milk cow nipple medicated bath agent and its preparation method and application
CN109077940A (en) * 2018-08-23 2018-12-25 山西纳安生物科技有限公司 A kind of beauty mask and preparation method thereof of electrolysis water preparation

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Application publication date: 20190702