CN109938700A - A kind of wear-type IR fluorescence detection device - Google Patents
A kind of wear-type IR fluorescence detection device Download PDFInfo
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- CN109938700A CN109938700A CN201910269450.3A CN201910269450A CN109938700A CN 109938700 A CN109938700 A CN 109938700A CN 201910269450 A CN201910269450 A CN 201910269450A CN 109938700 A CN109938700 A CN 109938700A
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- 238000001917 fluorescence detection Methods 0.000 title claims abstract description 20
- 238000001514 detection method Methods 0.000 claims abstract description 23
- 230000005284 excitation Effects 0.000 claims abstract description 17
- 239000000523 sample Substances 0.000 claims abstract description 12
- 230000003287 optical effect Effects 0.000 claims description 24
- 238000004891 communication Methods 0.000 claims description 16
- 230000001105 regulatory effect Effects 0.000 claims description 9
- 239000011521 glass Substances 0.000 claims description 6
- 230000002269 spontaneous effect Effects 0.000 claims description 3
- 238000009738 saturating Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 230000000007 visual effect Effects 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 239000004411 aluminium Substances 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 210000002990 parathyroid gland Anatomy 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000001506 fluorescence spectroscopy Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 description 1
- 229960004657 indocyanine green Drugs 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The present invention relates to a kind of wear-type IR fluorescence detection devices, including wearing detection device and display device, it is described to wear detection unit, control unit, power supply unit and the helmet, the probe unit is set to the helmet front, probe unit front end is equipped with the IR fluorescence excitation mechanism for exciting human autofluorescence, probe unit rear end is equipped with first shell, the interior source-collector mechanism being equipped with for collecting human body autofluorescence and generating image of first shell, the source-collector mechanism includes the fluorescence video camera being set to inside first shell and the camera lens that is set on IR fluorescence excitation mechanism and is connected with fluorescence video camera, first shell is fixedly connected with the helmet.The present invention can make doctor individually carry out fluorescence detection operation while operation, without assisting doctor as wear-type detection device.
Description
Technical field
The present invention relates to medical wearable device technical fields, and in particular to a kind of wear-type IR fluorescence detection device.
Background technique
Optical diagnostics is the important content of Biomedical Photonics, it is to check and analyze disease using optical method
Disease.The technology of optical diagnostics can be divided into two classes: spectral diagnosis of tissue and organism optical imaging diagnosis.Induced with laser is glimmering self
Light spectral technique is a kind of effective optical diagnostic method.It can be early diagnosed and be provided for many illnesss using fluorescence spectroscopy technique
Experimental basis, this technology is developed at present, is gradually applied to the optical diagnostics of human lesion tissue.
The autofluorescence that human body different tissues are issued under the excitation of exciting light is different, and same group is woven in by different waves
When section excitation, generated spontaneous fluorescence intensity and wave band also have difference.Existing autofluorescence detection dress at present
It in setting, is scanned mostly using point type, feedback, actual use is generated after the auto flourescence signals for receiving destination organization generation
In, it is not easy to there are observation and detection definitely to the case where destination organization.And existing autofluorescence detection device is big
Mostly Handheld detection device needs additional auxiliary doctor's handheld detection device to carry out aided detection, wave when being diagnosed
Take manpower.
Summary of the invention
In order to overcome the above problem, the present invention provides a kind of wear-type IR fluorescence detection devices, by the helmet 7
Infra-red detection mechanism and source-collector mechanism are set, fluorescence detection device is worn on, liberated auxiliary doctor, simultaneously
By using Fluorescence Fluorescence video camera 5 as source-collector and wearable display, the autofluorescence detected is converted to
The problem of fluorescent image is simultaneously transmitted on wearable display, can solve the switching of the doctor visual field.
The present invention is achieved by the following technical solutions:
A kind of wear-type IR fluorescence detection device, which is characterized in that described including wearing detection device and display device
Detection unit, control unit, power supply unit and the helmet are worn, the probe unit is set to the helmet front, visits
It surveys unit front end and is equipped with the IR fluorescence excitation mechanism for being used for exciting human autofluorescence, probe unit rear end is equipped with first shell
Body, the interior source-collector mechanism being equipped with for collecting human body autofluorescence and generating image of first shell, the source-collector machine
Structure include the fluorescence video camera being set to inside first shell and be set on IR fluorescence excitation mechanism and with fluorescence video camera
Connected camera lens, first shell are fixedly connected with the helmet；
Described control unit includes second shell, and the second shell is fixedly arranged on helmet side, is equipped with electricity in second shell
Road plate, the circuit board pass through between each module including including the first control module, the first communication module, the first power module
Route is connected, and the first circuit board is connected with IR fluorescence excitation mechanism and source-collector mechanism by route；
The power supply unit includes battery compartment, and the battery compartment is fixedly arranged on helmet rear portion, and battery compartment and first circuit board are logical
It crosses route to be connected, battery is equipped in the battery compartment；
Preferably, the IR fluorescence excitation mechanism includes the lamp panel for being set to housing forward end, is equipped in the middle part of the lamp panel
Lens through hole, lamp panel front end are equipped with condenser lens in parallel, and lens through hole is surrounded on the lamp panel surface between condenser lens and lamp panel
Several infrared emission tubes are provided with, lamp panel is fixedly connected with first shell；
The camera lens is set in lens through hole；
Preferably, the infrared emission tube is annular array arrangement, and quantity is 20-100 root；
Preferably, the wavelength of transmitted light of the infrared emission tube is one of 660nm, 700nm, 750nm, 785nm；
Preferably, the fluorescence video camera includes photosensitive element, and optical filter is equipped with before the photosensitive element；
Preferably, the cutoff wavelength of the optical filter is one of 660nm, 700nm, 750nm, 785nm；
Preferably, the cut-off depth of the optical filter is OD4-OD6；
Preferably, the display device includes frame, device noumenon, display screen, and the frame includes temple and eyeglass, dress
It sets ontology to be installed in temple, device noumenon one end connects display screen, and the display screen is arranged in parallel in front of eyeglass；
Described device ontology includes third shell and second circuit board, and the second circuit board is set to interior of shell, described
Circuit board includes the second communication module, the second control module, second power supply module, by connection between each module, second
Control module is connect with display screen；
Preferably, the display device is Google glass；
Preferably, the first shell is equipped with regulating switch, and the regulating switch is connect by route with circuit board.
The invention has the benefit that (1) wear-type detection device, can be such that doctor individually carries out while operation glimmering
Optical detection operation, without assisting doctor；(2) use fluorescence video camera as source collectors, it can directly will be collected
Auto flourescence signals are converted to picture signal and are output to computer screen, and doctor is allow intuitively to watch and diagnose；(3) make
With wearable display screen, doctor can be made to watch display screen without rotary head, facilitate surgical procedure；(4) exciting light is whole using annular
It is uniform to be formed by spot intensity for column distribution；(5) optical filter is set before fluorescence video camera photosensitive element, can be effectively reduced spy
Survey noise.
Detailed description of the invention
Fig. 1 is the application structure chart.
Fig. 2 is IR fluorescence excitation mechanism sectional view.
Fig. 3 is display device structure figure.
In figure, 1, infrared emission tube, 2, camera lens, 3, condenser lens, 4, lamp panel, 5, fluorescence video camera, 6, first shell,
7, the helmet, 8, battery compartment, 9, regulating switch, 10, first circuit board, 11, second shell, 12, photosensitive element, 13, optical filter,
14, lens through hole, 15, temple, 16, second circuit board, 17, third shell, 18, display screen, 19, eyeglass.
Specific embodiment
Here is that the present invention is further described in conjunction with the accompanying drawings and embodiments.
Embodiment 1
As shown in Figure 1, Figure 2, Figure 3 shows, a kind of wear-type IR fluorescence detection device, including wear detection device and display dress
It sets, wears detection device and be made of probe unit, control unit, power supply unit and the helmet 7, the helmet 7 is arranged in probe unit
Front is fixedly connected with the helmet 7.Probe unit is divided into two parts, and front end is that probe unit front end is equipped with for exciting human certainly
The IR fluorescence excitation mechanism to fluoresce, IR fluorescence excitation mechanism are made of collector lens, lamp panel 4, infrared emission tube 1,
The center of lamp panel 4 offers a lens through hole 14, and collector lens shape size is identical as lamp panel 4, is fixedly installed on lamp
The front of disk 4, collector lens be parallel to lamp panel 4 and with 4 concentric of lamp panel, there are gap, infrared rays between collector lens and lamp panel 4
On surface of the transmitting tube 1 by the evenly distributed side close to condenser lens 3 that is mounted on lamp panel 4 of annular, annular arrangement can guarantee
It is formed by that spot intensity is uniform, the quantity of infrared emission tube 1 can carry out between 20-50 root according to required intensity
Selection；The launch wavelength of infrared emission tube 1 can according to need with the case where selected, as parathyroid gland operation in,
Since the autofluorescence central wavelength of parathyroid gland is in 820nm or so, 785nm infrared emission tube 1 can choose, and often at present
It with the fluorescence of coloring agent indocyanine green in 810nm, therefore can choose 750nm or 785nm is excited, also can be used
660nm or 700nm exciting light cooperates methylenum careuleum to carry out lymph dyeing imaging；Lamp panel 4 selects the good aluminium of heating conduction as material
Material generates amount of heat when infrared emission tube 1 works, and aluminium can help infrared emission tube 1 to radiate.
The rear end of probe unit is equipped with first shell 6, and 6 front end of first shell is fixedly connected with lamp panel 4, and rear end is fixed on head
On helmet 7, enclosure interior is source-collector mechanism, and source-collector mechanism is made of camera lens 2, fluorescence video camera 5, and the setting of camera lens 2 exists
In the lens through hole 14 at 4 center of lamp panel, for collecting the autofluorescence light that search coverage tissue is issued after infrared ray excited
Signal, camera lens 2 pass through lens through hole 14 and connect with fluorescence video camera 5, and camera lens 2 uses automatic zoom camera lens 2, can automatically adjust
Focal length, autofluorescence optical signal received by camera lens 2 is transmitted to fluorescence video camera 5, photosensitive by being equipped in fluorescence video camera 5
Element 12 receives and generates image；Optical filter is provided with before photosensitive element 12, optical filter can be emitted infrared emission tube 1
Exciting light via organizing irreflexive reflected light to filter out, the noise of detection is reduced, according to used infrared emission tube 1
Difference selects the optical filter of identical cutoff wavelength to be cooperated, and optical filter, can be with using the optical filter of cut-off depth OD4-OD6
Preferably cutoff wavelength is filtered.
Control unit is set to 7 side of the helmet, including second shell 11, second shell 11 are fixedly connected with the helmet 7, second shell
Body 11 is internally provided with circuit board, and circuit board includes for the control module of control, for leading to what display device was communicated
News module, the power module composition for manage power supply, are connected with each other between each module, circuit board pass through route respectively with it is infrared
Fluorescence excitation mechanism is connected with source-collector mechanism.11 outer surface of second shell is additionally provided with regulating switch 9, regulating switch 9 with
Internal circuit board connection, for the switch of control device.When the switch is opened, control module receives 9 signal control of regulating switch
Electric power source pair of module infrared emission tube 1 processed is powered with fluorescence video camera 5, after the autofluorescence excited is collected via camera lens 2, is passed
It is delivered to fluorescence video camera 5, after converting optical signals to electric signal by fluorescence video camera 5, is transmitted to the communication module of circuit board, is schemed
It is shown as being transmitted to display device via communication module.
Power supply unit is set to 7 rear portion of the helmet, including battery compartment 8, is equipped with battery in battery compartment 8, battery compartment 8 by route with
Circuit board connection, is powered by power module management.
Display device includes frame and device noumenon, and frame is made of temple 15 and eyeglass 19, and device noumenon is by third shell
Body 17 is formed with the second circuit board 16 being arranged in inside third shell 17, and third shell 17 can be screwed and be mounted on
In temple 15, one end of third shell 17 stretches out frame and connects one piece of small-sized display screen 18, display screen 18 and eyeglass 19
It is arranged in parallel, is connect by route with the second wiring board, user can directly see aobvious very much when being observed by eyeglass 19
Display screen 18.
Second circuit board 16 include the second communication module, the second control module, second power supply module, the second communication module with
First communication module is wirelessly connected, and for receiving the image information that detection device passes over, is handled via the second control module
Afterwards, it passes to display screen 18 to be shown, second power supply module is used to the second communication module, the second control module and display screen
18 power supplies.After tissue autofluorescence signal collected by camera lens 2 is converted to image by fluorescence video camera 5, obtained figure
As being transmitted to the second communication module by the first communication module, after being handled via the second control module, image information is transmitted to
It is shown on display screen 18, doctor directly can observe display screen by eyeglass 19 while observing by eyeglass 19
Fluorescent image on 18, without switching the visual field.
When being detected using the present apparatus, the helmet 7 to be dressed to head, the frame of display device is clothed to eye position,
The regulating switch 9 in second shell 11 is clicked, the control module on circuit board receives instruction, controls electric power source pair of module IR fluorescence
Excitation mechanism is powered with source-collector mechanism, and infrared emission tube 1 is lighted, and irradiates detected part, detected part is through exciting
Generate autofluorescence, generated fluorescence is collected via camera lens 2, is transmitted in video camera, after optical filter filters by
Photosensitive element 12 converts optical signals to electric signal, is transmitted to the first communication module of circuit board, is passed through by the first communication module
After second communication module of wireless transmission to display device is handled via the second control module, image information is transmitted to display screen
It is shown on 18, doctor can directly be observed on display screen 18 by eyeglass 19 while being observed by eyeglass 19
Fluorescent image, without switching the visual field.
Embodiment 2
A kind of wear-type IR fluorescence detection device, including wear detection device and display device, wear detection device with
Embodiment 1 is identical, display device use google glass Google glass, by Google glass by wirelessly with the first communication module
Connection, the fluorescent image generated of fluorescence video camera 5 can be transmitted in Google glass and be directly observed.
Claims (10)
1. a kind of wear-type IR fluorescence detection device, which is characterized in that including wearing detection device and display device, the head
Detection unit, control unit, power supply unit and the helmet are worn, the probe unit is set to the helmet front, detection
Unit front end is equipped with the IR fluorescence excitation mechanism for exciting human autofluorescence, and probe unit rear end is equipped with first shell,
The interior source-collector mechanism being equipped with for collecting human body autofluorescence and generating image of first shell, source-collector mechanism packet
The camera lens for including the video camera being set to inside first shell and being set on IR fluorescence excitation mechanism and being connected with video camera, the
One shell is fixedly connected with the helmet；
Described control unit includes second shell, and the second shell is fixedly arranged on helmet side, is equipped with circuit board in second shell,
The circuit board passes through route phase between each module including including the first control module, the first communication module, the first power module
Even, the first circuit board is connected with IR fluorescence excitation mechanism and source-collector mechanism by route；
The power supply unit includes battery compartment, and the battery compartment is fixedly arranged on helmet rear portion, and battery compartment and first circuit board pass through line
Road is connected, and battery is equipped in the battery compartment.
2. a kind of wear-type IR fluorescence detection device according to claim 1, which is characterized in that the IR fluorescence excitation
Mechanism includes the lamp panel for being set to housing forward end, lens through hole is equipped in the middle part of the lamp panel, it is saturating that lamp panel front end is equipped with focusing in parallel
Mirror is provided with several infrared emission tubes around lens through hole on the lamp panel surface between condenser lens and lamp panel；
The camera lens is set in lens through hole.
3. a kind of human body spontaneous fluorescence detection device according to claim 2, which is characterized in that the infrared emission tube is
Annular array arrangement, quantity are 20-100 root.
4. a kind of human body spontaneous fluorescence detection device according to claim 3, which is characterized in that the infrared emission tube
Wavelength of transmitted light is one of 660nm, 700nm, 750nm, 785nm.
5. a kind of wear-type IR fluorescence detection device according to claim 1, which is characterized in that the video camera includes sense
Optical element is equipped with optical filter before the photosensitive element.
6. a kind of wear-type IR fluorescence detection device according to claim 5, which is characterized in that the cut-off of the optical filter
Wavelength is one of 660nm, 700nm, 750nm, 785nm.
7. a kind of wear-type IR fluorescence detection device according to claim 5, which is characterized in that the cut-off of the optical filter
Depth is OD4-OD6.
8. a kind of wear-type IR fluorescence detection device according to claim 1, which is characterized in that the display device includes
Frame, device noumenon, display screen, the frame include temple and eyeglass, and device noumenon is installed in temple, device noumenon one end
Display screen is connected, the display screen is arranged in parallel in front of eyeglass；
Described device ontology includes third shell and second circuit board, and the second circuit board is set to interior of shell, the circuit
Plate includes the second communication module, the second control module, second power supply module, passes through connection, the second control between each module
Module is connect with display screen.
9. a kind of wear-type IR fluorescence detection device according to claim 1, which is characterized in that the display device is paddy
Sing glasses.
10. a kind of wear-type IR fluorescence detection device according to claim 1, which is characterized in that in the first shell
Equipped with regulating switch, the regulating switch is connect by route with circuit board.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910269450.3A CN109938700A (en) | 2019-04-04 | 2019-04-04 | A kind of wear-type IR fluorescence detection device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910269450.3A CN109938700A (en) | 2019-04-04 | 2019-04-04 | A kind of wear-type IR fluorescence detection device |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110215193A (en) * | 2019-07-08 | 2019-09-10 | 济南显微智能科技有限公司 | A kind of quickly identification parathyroid gland autofluorescence face imaging spectrometer |
| CN114157851A (en) * | 2021-11-26 | 2022-03-08 | 长沙海润生物技术有限公司 | Wearable wound infection imaging device and imaging method |
| CN114189668A (en) * | 2021-11-26 | 2022-03-15 | 长沙海润生物技术有限公司 | Wearable wound surface imaging device and imaging method |
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