CN109908217A - It is a kind of for treating the Chinese medicine composition and application thereof of arterial thrombus obliterans - Google Patents
It is a kind of for treating the Chinese medicine composition and application thereof of arterial thrombus obliterans Download PDFInfo
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Abstract
The invention discloses a kind of for treating the Chinese medicine composition of arterial thrombus obliterans, and the bulk pharmaceutical chemicals such as radix aconiti lateralis preparata, Radix Astragali, ramulus cinnamomi, Radix Paeoniae Alba, peach kernel, safflower, leech, the dried immature fruit of citron orange, rheum officinale, asarum that the composition is matched by constant weight are made.The traditional chinese medicine composition of the invention has significant therapeutic effect to arterial thrombus disease, especially limb artery hardening obliterans.
Description
Technical field
The present invention relates to a kind of for treating the Chinese medicine composition and application thereof of arterial thrombus obliterans, belongs to traditional Chinese medicine neck
Domain.
Background technique
Arterial obliterans of lower extremity (arteriosclerosis obliterans, ASO) is due to Atherosclerosis
Change cause arterial intima to thicken, lead to thrombosis, make luminal stenosis or occlusion, cause limbs blood supply insufficiency it is chronic into
Malleability disease, clinical manifestation are low skin temperature drop, pain, lower limb intermittent claudication, ulcer or necrosis etc. even occur.According to epidemic disease
Investigation is learned, this disease is up to 15%~20% in 75 years old or more crowd's disease incidence, and the year case fatality rate of the patient is 4%~6%.
ASO patient's disability rate, case fatality rate are high, cause greatly personal and burden on society.In terms for the treatment of, operation method
The first choice for treating the disease is especially had become by Percutaneous intravascular balloon dilatation/stent endoprosthesis of iliac region approach.
Doctor trained in Western medicine internal medicine then mainly removes the inducements such as hypertension, hyperlipidemia, smoking, uses antiplatelet, anticoagulant, poly-, expansion blood vessel etc. of dispelling
Method.Arterial occlusion is attributed to the scopes such as " stasis blocking ", " vessle-Bi symptom-complex ", " acrotism card ", " syndrome of blood stasis " by traditional Chinese medicine.Healthy tendency virtual loss,
Push powerless, warm insufficient and cause internal organs underactivity, the operation of saliva blood and metabolism obstacle, produce internal organs function it is weak and
The pathological products such as " phlegm wet ", " hemostasis ", final retardance is in lower limb train of thought.Therefore in the middle treatment of lower extremity atherosclerotic disease
It is turbid with qi-restorativesization in treatment, lead to based on stasis of blood eliminating the phlegm, treating both manifestation and root cause of disease.
Summary of the invention
It is an object of that present invention to provide a kind of new Chinese medicine compositions, can be used for treating arterial obliterans of lower extremity etc.
Arterial occlusive disease.
To realize the goal of the invention, a kind of Chinese medicine composition is inventor provided, the effective component of the composition is by such as
Made of the bulk pharmaceutical chemicals of lower proportion: 10-30 parts of radix aconiti lateralis preparata, 15-40 parts of Radix Astragali, 9-30 parts of ramulus cinnamomi, 5-10 parts of Radix Paeoniae Alba, peach kernel 6-12
Part, 6-12 parts of safflower, 1-3 parts of leech, 6-12 parts of the dried immature fruit of citron orange, 6-12 parts of rheum officinale, 1-3 parts of asarum.
Preferably, the bulk pharmaceutical chemicals proportion of the Chinese medicine composition are as follows: 20-30 parts of radix aconiti lateralis preparata, 20-35 parts of Radix Astragali, ramulus cinnamomi 9-20
Part, 8-10 parts of Radix Paeoniae Alba, 8-10 parts of peach kernel, 8-10 parts of safflower, 2-3 parts of leech, 8-10 parts of the dried immature fruit of citron orange, 8-10 parts of rheum officinale, asarum 2-3
Part.
It is further preferred that the proportion of each bulk pharmaceutical chemicals are as follows: 30 parts of radix aconiti lateralis preparata, 30 parts of Radix Astragali, 9 parts of ramulus cinnamomi, 10 parts of Radix Paeoniae Alba, peach
9 parts of benevolence, 9 parts of safflower, 3 parts of leech, 9 parts of the dried immature fruit of citron orange, 9 parts of rheum officinale, 3 parts of asarum.
It has been recognised by the inventors that blood obtains Wen Zehang, meet to tremble with fear and then coagulate, trembling with fear solidifying is to lead to the thrombosed major reason of blood stasis.It is cold
Heresy can cause slow blood flow, blood stagnation and form extravasated blood；Meanwhile cold-evil causes passages through which vital energy circulates to shrink spasm, the inadequate urgency of blood vessels is then sent out as pain
Bitterly；Cold being a kind of YIN pathogen, easy impairment of yang gas, the deficiency of yang push blood powerless, aggravate thrombosis, the resistance of cold-evil's numbness with the passing of time can impairment of yang cause the deficiency of vital energy,
Develop into the card of simulataneous insufficiency and excessive, clinical manifestation with pain, it is out of strength based on.It controls with warming YANG and invigorating QI cold dispelling, activating microcirculation and removing stasis medicinal is method.Cause
And inventor foundes we, in which: with monkshood, Radix Astragali for monarch, the pungent Gan Xingre of monkshood, to warming kidney and enhancing yang with cold dispelling, Radix Astragali is sweet
The power of temperature, tonifying Qi is special, and two medicines share, and plays the function of warming YANG and invigorating QI altogether, with temperatureization, pushes blood operation；Minister is with ramulus cinnamomi, Radix Paeoniae Alba, peach
The benefits of benevolence, safflower, the pungent scattered temperature of ramulus cinnamomi is logical, and principal drug assistance monkshood temperature is positive, peach kernel, safflower enter conscience blood system, grasp the property of pungent-warm, and promoting blood circulation is dispelled
The stasis of blood, Radix Paeoniae Alba are sour to hold back yin, blood-nourishing analgesic；Assistant is with the dried immature fruit of citron orange, pungent row hardship drop, and relieving stagnant Qi dissipates ruffian, rheum officinale weeding through the old to new, dispelling stasis of blood and stimulating the menstrual flow, both
Can descend hemostasis again can clear stagnant heat, asarum pungent-warm walks to alter, and tonneau nine orifices, leech insect medicine physical property is apt to walk to alter, extending from the interior to the exterior, blood-breaking by
The stasis of blood.Such prescription makes warming kidney and enhancing yang with cold dispelling, inrigorating qi and promoting blood circulation with stagnation resolvation, it is kind control arterial thrombus obliterans, limb artery hardening is closed
The arterial thrombus diseases such as disease are filled in, syndrome of yang deficiency and blood stasis patient is belonged to.
Above-mentioned Chinese medicine composition, which is used alone, can be realized the purpose of the present invention.In order to further enhance applicability or raising
Other ancillary drugs can also be added according to the needs of clinical disease in effect, and the most commonly used is 8-10 parts of scorpios, trigone 8-10
Part and curcuma zedoary 8-10 part, preferably after three taste medicines proportion be 9:9:9.
When in use, the traditional chinese medicine composition of the invention after decocting with water, can take soup to take by prescription conventional use.It can also
With with water or other appropriate solvents, after refining to the effective component of prescription, routinely preparation process, is made various solid systems
Agent, such as tablet, capsule, granule.
Beneficial effect
Pharmaceutical composition of the present invention is as preparation in institute, by the compliance test result of nearly thousand clinical cases, trembles with fear blood coagulation for the deficiency of yang
Arterial occlusive disease caused by the stasis of blood has significant curative effect, it may not be necessary to cooperate Western medicine to use and be able to achieve therapeutic purposes.Especially
For the gerontal patient of YANG QI deficiency, can be realized by the function of improvement body by this and target therapeutic effect.Be below from
The typical case selected in clinic.
1, the male lower extremities first visit 2017/6/27 in 64 years old of one woods X of case
Main suit: double lower limb pain out of strength more than 3 years.
Inscribe disease: double lower limb is out of strength obvious, and double-legged pain, feeling of numbness, level land walking 10m need to stop resting, double lower limb
Consciously send out cool, chilly, receive food can, sleep it is poor, defecate 2-3 days a line, matter do, urine tune.The dark yellow and greasy fur stringy and tense pulse of tongue.
Auxiliary examination: double lower limb artery color ultrasound: right external iliac artery severe stenosis；Left external iliac artery moderate stenosis, double lower limb
II phase of ischemic；
Past medical history: diabetes more than 15 years, May after more than 40 years coronary heart disease Coronary Artery Bypass of hypertension
Doctor trained in Western medicine diagnosis: lower extremities, Carotid Sclerosis, coronary heart disease, CABG are postoperative
Differential diagnosis in tcm: cold blood stasis
Therapy: warming yang for dispelling cold, activating microcirculation and removing stasis medicinal
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: according to card tongue vein, limbs of patient pain numbness very, dark tongue quality, this silt up for blood stasis stagnation of the circulation of vital energy vascular it is obstructed, therefore in original side
On the basis of plus with the trigone of breaking blood and promoting the circulation of qi strength severe one, curcuma zedoary, scorpio assistant to lead to the stasis of blood.
Further consultation 1
Inscribe disease: slowly walking freely with can now being descended after medication, pain, it is out of strength improve earlier above, toe has been felt, dry be intended to
Drink, easy sweating, receive can, sleep still, a line on the 2nd of defecating, forming, matter is slightly dry, and defecation is slightly laborious, small.The dark tongue fur of tongue is thin, arteries and veins
It is heavy.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: rhizoma zingiberis 9g, radix glycyrrhizae preparata 10g, radix achyranthis bidentatae 15g
Fang Xie: head examines and takes prescription 14 and pay, and patient can walk with descending.According to card tongue vein, though limbs pain numbness subtracts, symptom is still
In, solidifying then stagnation of QI and blood of trembling with fear, hematogenous blockage, in rhizoma zingiberis, radix glycyrrhizae preparata temperature and in；Have defecation laborious again, thus compatibility radix achyranthis bidentatae to
By silt promoting menstruation, inducing diuresis for treating strangurtia.
Further consultation 2 2017/8/22
Inscribe disease: double lower limb pain improves obvious behind clothes top, walks unrestricted, still feels out of strength, without shortness of breath uncomfortable in chest, without dizzy head
Bitterly, receive dormancy can, a line on the 2nd of defecating, partially dry, urine is fine.The dark yellow,greasy and thin fur deeptensepulse of tongue.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: rhizoma zingiberis 9g, radix glycyrrhizae preparata 10g, radix achyranthis bidentatae 15g
Fang Xie: according to card tongue vein, limbs of patient pain improves, remaining not tell special discomfort, therefore keeps with 2017/7/25 Japanese side.
Further consultation 3 2017/9/19
Inscribe disease: freely, pain almost disappears for walking, and send out cool numb, out of strength to improve earlier above, skin cool feeling mitigation, without chest uncomfortable in chest
Bitterly, swelling and aching of gum, receive can, peace of sleeping, a line on the 3rd of defecating, matter is dry, small.The dark yellow and greasy fur stringy and tense pulse of tongue
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: rhizoma zingiberis 9g, radix glycyrrhizae preparata 10g, radix achyranthis bidentatae 15g
Fang Xie: according to card tongue vein, limbs of patient pain improves, remaining not tell special discomfort, therefore continues to keep with 2017/7/25 Japanese side.
Further consultation 4 2017/10/17
Inscribe disease: walking behind clothes top as usual, pain disappears, and except the slightly right crus of diaphragm palm is numb, has dry skin itch, it is remaining do not tell it is special
Discomfort, receive can, dormancy is felt unwell, defecate 2-3 day a line, matter partially dry, urine tune.The dark yellow and greasy fur of tongue, veins string.
Auxiliary examination: double lower limb artery ultrasound (2017-9-21): double lower limb artery sclerosis is formed with patch, and double lower limb is deep
Vein no abnormality seen；
It is biochemical: LDL 1.35, HDL 1.06, TG 0.73;Glycosylated hemoglobin 6.1
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: rhizoma zingiberis 9g, radix glycyrrhizae preparata 10g, radix achyranthis bidentatae 15g
Fang Xie: confessing one's crime between having examined April, and patient takes Fang Wuci altogether, does not during which take other drugs, and lower limb pain gradually mitigates directly
To disappearance, and it is lower walk as usual, remaining all disease compatibility plus-minuss are become better, former Fang Youxiao, therefore continue to keep with power.If there is discomfort
Follow-up.
2, the abundant XX female of case two left lower extremity arterial occlusion first visit 2017/7/25 in 70 years old
Main suit: double lower limb pain out of strength more than 2 years.
Inscribe disease: double lower limb is out of strength, walking 10 meters after i.e. there is pain, trick is sent out cool, and dry is not bitter, receive dormancy can, two just adjust.Tongue
The thin deeptensepulse of dark tongue fur.
Auxiliary examination: double lower limb artery color ultrasound: right lower extremity arterial occlusion, the right total severe stenosis of stock, left femoral artery,superficial moderate
Narrow, before bilateral shin and left side artery occludes
Doctor trained in Western medicine diagnosis: arterial occlusions in lower limbs, hyperlipidemia
Differential diagnosis in tcm: cold blood stasis
Therapy: warming yang for dispelling cold, activating microcirculation and removing stasis medicinal
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: auxiliary examination prompt, limbs of patient arterial occlusion is with severe stenosis is shown in, the stagnant obstructed event pain of blood stasis, honor is supported unfavorable
Then lower limb are out of strength, this for blood stasis stagnation of the circulation of vital energy vascular silt up it is obstructed caused by, therefore the stasis of blood led to breaking blood and promoting the circulation of qi with trigone, curcuma zedoary, scorpio assistant.
Further consultation 1
It inscribes disease: behind clothes top, can adhere to that travel distance increases earlier above, but still have double lower limb still out of strength, right side is obvious, trick hair
It is cool, receive dormancy can, two just adjust.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: rhizoma zingiberis 9g, radix glycyrrhizae preparata 10g, radix achyranthis bidentatae 15g
Fang Xie: according to card tongue vein, solidifying then blood stasis of trembling with fear, hematogenous blockage, it is unfavorable that tendon and vessel supports, therefore shows as trick and send out cool, with rhizoma zingiberis, sweet
In grass temperature and middle promoting menstruation, compatibility monkshood warm kidney help sun.Add with radix achyranthis bidentatae nourishing liver and kidney, ensuring proper downward flow of the blood.
Two 2017-11-07 of further consultation
Inscribe disease: double lower limb is out of strength to improve obviously, and walking, though there is pain, can be resistant to simultaneously than before to 100 meters or so
Walk on, the soreness of waist, even dry mouth with bitter taste, chilly, easy sweating, the palm of the hand is clammy, receive can, even difficulty falling asleep, defecate 1-2 days a line,
Morphoplasm is glutinous, oliguria.The dark red tongue fur of tongue is few, deeptensepulse.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: rhizoma zingiberis 9g, radix glycyrrhizae preparata 10g, dendrobium nobile 12g
Fang Xie: patient takes two powers, does not during which take other drugs, and lower limb are out of strength to be clearly better, travel distance obviously increase and
Pain degree mitigates earlier above, can adhere to walking on, but still has chilly the cold and cool disease such as to send out cool；According to card tongue vein, the dark deeptensepulse of tongue, then
Continue plus use rhizoma zingiberis, radix glycyrrhizae preparata；There is dry mouth with bitter taste again, therefore with dendrobium nobile nourishing Yin and promoting production of body fluid.Uncomfortable follow-up.
3, three king XX female of case right lower extremity arterial occlusion first visit 2017/6/20 in 61 years old
Main suit: right lower extremity pain more than 4 years.
: there is right lower extremity pain when walking before 4 years in present illness history, cures three institute's row lower extremities ct angiographies in north, finds right lower extremity
Femoral artery,common occludes and is implanted into 2 pieces of brackets, and postsurgery symptoms are alleviated.Because occluding row dilatation, it is implanted into 2 pieces again within 2015 within 2014
Bracket, row dilatation in 2016, check right lower extremity arterial occlusion in 2017, left side occlusion 80%.
Inscribe disease: right lower extremity pain, chilly, four limbs are ice-cold, receive it is few, when have nausea, sleep general, oliguria is defecated 2 days one
It is secondary, the dark yellow and greasy fur of tongue, deeptensepulse.
Doctor trained in Western medicine diagnosis: arterial occlusions in lower limbs, hyperlipidemia
Differential diagnosis in tcm: cold blood stasis
Therapy: warming yang for dispelling cold, activating microcirculation and removing stasis medicinal
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: it is serious that patient head examines arterial occlusions in lower limbs situation, and involves Multivessel, and critical constraints are supported in limbs honor, therefore are showed
For the diseases such as pain, chilly, four limbs are ice-cold.According to card tongue vein, patient's lower limb pain chilly, four limbs are ice-cold, dark tongue quality, deeptensepulse, this is
The performance of blood stasis due to accumulation of cold, vascular obstruction, therefore with medicines such as the breaking blood and promoting the circulation of qi such as trigone, curcuma zedoary, scorpio, enhance the function by silt promoting menstruation
Effect.
Further consultation 1
Inscribe disease: right lower extremity pain behind clothes top swells, send out heavy substantially reduced earlier above, and right lower extremity color obviously shoals earlier above, fears
Cold degree mitigates, dizziness out of strength, and nausea is without vomiting, abdominal distension, hiccup bitter taste, receive can, sleep shallow, day a line of defecating, forming, matter is glutinous,
Oliguria.The dark greasy and thin fur of tongue, deep tense pulse.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: Longstamen Onion Bulb 10g, rhizoma pinellinae praeparata 9g, Rhizoma Atractylodis Macrocephalae 15g
Fang Xie: clothes top is more than the moon, and limbs of patient pain is heavy i.e. substantially reduced, and skin color improves obviously earlier above, former Fang Youxiao；
According to card tongue vein, patient has dizziness and nausea, stool to stick greasy, greasy and thin fur, is phlegm wet performance, then assistant helps resolving sputum with Longstamen Onion Bulb, the tuber of pinellia, Rhizoma Atractylodis Macrocephalae
Clearing damp.
Further consultation 2 2017/9/12
Inscribe disease: right lower extremity pain there are few, lower limb are out of strength heavy substantially reduced, and still nausea is without vomiting, no dizziness headache, receive can,
Sleep can, 1 row of day of defecating, shapeless, matter is glutinous, and urine amount is few.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: Longstamen Onion Bulb 10g, rhizoma pinellinae praeparata 9g, Rhizoma Atractylodis Macrocephalae 15g
Fang Xie: according to card tongue vein, limbs of patient pain disappears substantially, remaining not tell special discomfort, former Fang Youxiao, therefore continues to keep use
2017/8/22 Japanese side.Uncomfortable follow-up.
4, four XX female Min of case right lower extremity arterial occlusion first visit 2017/8/8 in 65 years old
Main suit: it double lower limb 2 years out of strength, aggravates with pain 1 year.
Inscribe disease: double lower limb pain out of strength is sent out cool numb, and very, skin color is normal on right side, no chest pain uncomfortable in chest, and shortness of breath is weary
Power, no aversion to cold, easy sweating, dry mouth with bitter taste, receive dormancy can, greatly, urine color is yellow.Pale tongue with thin fur, stringy and tense pulse.
Auxiliary examination: double lower limb rheography (2016-10-26 Pok Oi Hospital): the slight arterial occlusive blood supply of right side limbs
It is insufficient；Double lower limb Deep venou and iliac vein are unobstructed.
Past medical history: coronary heart disease 10 years, 3 pieces of brackets are placed in Xuan Wu hospital because of heart infarction within 2007；More than first subtracts 5 year；2007
Side nephrarctia is found when row PIC；Carotid artery stenosis；Deny DM；Hyperuricemia, dysfunction of liver.
Doctor trained in Western medicine diagnosis: hyperuricemia differential diagnosis in tcm after Leg trauma coronary artery stent implantation: cold blood stasis
Therapy: warming yang for dispelling cold, activating microcirculation and removing stasis medicinal
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: auxiliary examination prompt, limbs of patient arterial occlusive blood supply insufficiency, honor support that unfavorable then lower limb are out of strength, and blood stasis is stagnant not
Logical therefore pain, this for blood stasis stagnation of the circulation of vital energy vascular silt up it is obstructed caused by, therefore the stasis of blood is led to breaking blood and promoting the circulation of qi with trigone, curcuma zedoary, scorpio assistant.
Further consultation 1
Inscribe disease: night double lower limb pain is hardly seen, but still daytime walking is unfavorable, and pain numbness mitigates, out of strength slightly to subtract, sweating
Excessively, above the waist more so, even dry mouth, occasionally has uncomfortable in chest, and happiness length is had a respite, receive dormancy can, stool day 1-2 times, matter is partially dilute, urine night
Frequently, 3-4 times/night, pale tongue, greasy and thin fur, stringy and tense pulse.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: patient subtracts daytime symptoms still exist at lower limb pain night behind clothes top, still slightly discomforts such as numb, out of strength.Because of blood stasis
Disease weight, original side basis, with the scorpio of breaking blood and promoting the circulation of qi strength severe one, trigone, curcuma zedoary, keep hemostasis general rule blood smooth, Rong Yangsi after assistant
Limb.
5, the male bilateral arterial plaque first visit 2017/8/8 in 69 years old of five Xu XX of case
Main suit: double lower limb pain 3 years.
: there is double lower limb pain without obvious inducement before 3 years in present illness history, influences to walk, and 100 meters of walking need to rest, and double lower limb is without swollen
Swollen sense, color of the leather show without change, in June, 2017 in Beijing Hospital's row double lower limb artery enhanced CT: bilateral arterial patch is narrow, right side
Seriously, refuse Stent Implantation.
Inscribe disease: double lower limb pain aggravates, right hand feeling of numbness after activity, and such as ant row, rest is alleviated, left gonalgia, the soreness of waist
Bitterly, no feeling of oppression and pain in the chest, receive can, difficulty falling asleep, two just adjust.The dark greasy and thin fur of tongue, stringy and tense pulse.
Past medical history: hypertension 7 years, deny the medical histories such as coronary heart disease, diabetes, hyperlipidemia.
Doctor trained in Western medicine diagnoses: Leg trauma, antihyperuricemic after coronary artery stent implantation
Differential diagnosis in tcm: cold blood stasis
Therapy: warming yang for dispelling cold, activating microcirculation and removing stasis medicinal
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: for many years, the vascular stasis of blood is low and deep, with the passing of time muscles flesh bone dystrophy, then pain numbness, ant row occurs for patient's arterial occlusions in lower limbs
Equal abnormal sensories.Primarily the logical stasis of blood, Gu Zuo help breaking blood and promoting the circulation of qi with trigone, curcuma zedoary, scorpio.
Further consultation 1
Inscribe disease: double lower limb pain mitigates obviously earlier above, and walking distance increases by 300 meters or so earlier above, and right hand feeling of numbness mitigates, left
Knee joint still has pain, soreness of waist pain, no feeling of oppression and pain in the chest, receive can, difficulty falling asleep, two just adjust.The dark greasy and thin fur of tongue, stringy and tense pulse.
Prescription:
Square foundation: radix aconiti lateralis preparata (elder generation) 30g, Radix Astragali 30g, ramulus cinnamomi 9g, peach kernel 9g, safflower 9g, Radix Paeoniae Alba 10g, leech 3g, dried immature fruit of citron orange 9g,
Rheum officinale 9g, asarum 3g
Dosing: scorpio 9g, trigone 9g, curcuma zedoary 9g
Fang Xie: patient's travel distance obviously increases earlier above, and the diseases such as pain numbness are also taken a favorable turn, remaining not tell discomfort, former Fang Youxiao.
Therefore it keeps with 2017/8/8 Japanese side.Uncomfortable follow-up.
Specific embodiment
It should be appreciated that the embodiment of the present invention is merely to illustrate the contents of the present invention, the protection being not intended to restrict the invention
Range.Using design of the invention to the simple modifications that carry out of the present invention all within the scope of the claimed invention.In practice,
Following embodiment can obtain effect desired by the present invention.
Implement 1: taking radix aconiti lateralis preparata 30g, Radix Astragali 40g, ramulus cinnamomi 30g, Radix Paeoniae Alba 10g, peach kernel 12g, safflower 12g, leech 3g, the dried immature fruit of citron orange
12g, rheum officinale 12g, asarum 3g, by traditional handicraft, to be decocted in water for oral dose, one dose per day, 15 as a treatment course.
Embodiment 2: radix aconiti lateralis preparata 10g, Radix Astragali 15g, ramulus cinnamomi 9g, Radix Paeoniae Alba 5g, peach kernel 6g, safflower 6g, leech 1g, the dried immature fruit of citron orange are taken
6g, rheum officinale 6g, asarum 1g, by traditional handicraft, to be decocted in water for oral dose, one dose per day, 15 as a treatment course.
Embodiment 3: radix aconiti lateralis preparata 30g, Radix Astragali 30g, ramulus cinnamomi 30g, Radix Paeoniae Alba 10g, peach kernel 10g, safflower 10g, leech 2g, trifoliate orange are taken
Real 10g, rheum officinale 10g, asarum 2g, by traditional handicraft, to be decocted in water for oral dose, one dose per day, 15 are as a treatment course.
Embodiment 4: radix aconiti lateralis preparata 20kg, Radix Astragali 20kg, ramulus cinnamomi 9kg, Radix Paeoniae Alba 8kg, peach kernel 8-10kg, safflower 8kg, leech are taken
2kg, dried immature fruit of citron orange 8kg, rheum officinale 8kg, asarum 2kg are added water to cook 3 times, and for the first time plus 10 times of amounts of water decoct 1.5 hours, after add twice
6 times of amounts of water decoct 1 hour, and merging filtrate is concentrated under reduced pressure into paste, adds customary adjuvant that granule is made.
Embodiment 5: radix aconiti lateralis preparata 30kg, Radix Astragali 35kg, ramulus cinnamomi 20kg, Radix Paeoniae Alba 10kg, peach kernel 10kg, safflower 10kg, water are taken
Leech 3kg, dried immature fruit of citron orange 10kg, rheum officinale 10kg, asarum 3kg are added water to cook 2 times, and every time plus 8 times of amounts of water decoct 1 hour, merging filtrate,
Paste is concentrated under reduced pressure into, customary adjuvant is added, tablet is made.
Embodiment 6: radix aconiti lateralis preparata 30kg, Radix Astragali 20kg, ramulus cinnamomi 20kg, Radix Paeoniae Alba 10kg, peach kernel 10kg, safflower 10kg, water are taken
Leech 2kg, dried immature fruit of citron orange 10kg, rheum officinale 8kg, asarum 3kg are added water to cook 2 times, and for the first time plus 10 times of amounts of water decoct 1.5 hours, and second
8 times of amounts of water are added to decoct 1 hour, merging filtrate is concentrated under reduced pressure into paste, customary adjuvant is added, capsule is made.
Claims (7)
1. a kind of for treating the Chinese medicine composition of arterial thrombus obliterans, it is characterised in that the effective component of the Chinese medicine composition
It is made of the bulk pharmaceutical chemicals of following weight proportion: 10-30 parts of radix aconiti lateralis preparata, 15-40 parts of Radix Astragali, 9-30 parts of ramulus cinnamomi, Radix Paeoniae Alba 5-10
Part, 6-12 parts of peach kernel, 6-12 parts of safflower, 1-3 parts of leech, 6-12 parts of the dried immature fruit of citron orange, 6-12 parts of rheum officinale, 1-3 parts of asarum.
2. Chinese medicine composition according to claim 1, it is characterised in that the proportion of each bulk pharmaceutical chemicals are as follows: 20-30 parts of radix aconiti lateralis preparata,
20-35 parts of Radix Astragali, 9-20 parts of ramulus cinnamomi, 8-10 parts of Radix Paeoniae Alba, 8-10 parts of peach kernel, 8-10 parts of safflower, 2-3 parts of leech, 8-10 parts of the dried immature fruit of citron orange,
8-10 parts of rheum officinale, 2-3 parts of asarum.
3. Chinese medicine composition according to claim 2, it is characterised in that the proportion of each bulk pharmaceutical chemicals are as follows: 30 parts of radix aconiti lateralis preparata, Huang
30 parts of stilbene, 9 parts of ramulus cinnamomi, 10 parts of Radix Paeoniae Alba, 9 parts of peach kernel, 9 parts of safflower, 3 parts of leech, 9 parts of the dried immature fruit of citron orange, 9 parts of rheum officinale, 3 parts of asarum.
4. Chinese medicine composition according to any one of claim 1 to 3, it is characterised in that further include such as prescribe medicine in bulk pharmaceutical chemicals
Object: 8-10 parts of scorpio, 8-10 parts of trigone, 8-10 parts of curcuma zedoary.
5. Chinese medicine composition according to claim 4, it is characterised in that the weight proportion of scorpio, trigone and curcuma zedoary is 9:9:
9。
6. Chinese medicine composition described in any one of claims 1 to 5 is in preparing the drug for treating arterial thrombus disease
Using.
7. purposes according to claim 6, it is characterised in that the arterial thrombus disease refers to limb artery hardening occlusion
Disease.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110694014A (en) * | 2019-09-27 | 2020-01-17 | 陶开鑫 | A composition for preventing and treating thrombosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1122243A (en) * | 1995-08-16 | 1996-05-15 | 岳泰出 | Medicinal powder for eliminating embolism and invigorating blood circulation |
-
2019
- 2019-04-17 CN CN201910308304.7A patent/CN109908217B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1122243A (en) * | 1995-08-16 | 1996-05-15 | 岳泰出 | Medicinal powder for eliminating embolism and invigorating blood circulation |
Non-Patent Citations (1)
| Title |
|---|
| 王玉萍等: "温阳通脉汤治疗血栓闭塞性脉管炎120例", 《陕西中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110694014A (en) * | 2019-09-27 | 2020-01-17 | 陶开鑫 | A composition for preventing and treating thrombosis |
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