CN109907763A - Blood sugar detection apparatus - Google Patents
Blood sugar detection apparatus Download PDFInfo
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- CN109907763A CN109907763A CN201711316396.0A CN201711316396A CN109907763A CN 109907763 A CN109907763 A CN 109907763A CN 201711316396 A CN201711316396 A CN 201711316396A CN 109907763 A CN109907763 A CN 109907763A
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- detection apparatus
- blood sugar
- air inlet
- sugar detection
- liquid space
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Abstract
A kind of blood sugar detection apparatus includes: the carrier with accommodation groove and venthole in communication；Gas pump is set in accommodation groove and is driven with conduction gas, and an at least air inlet is arranged, and after supplied gas is imported by air inlet, then is discharged by venthole；Waterproof membrane is covered on air inlet；Microneedle patch is removably attached on carrier and covers air inlet, and with multiple empty micropins and the appearance liquid space communicated with empty micropin, holds liquid space and be connected with air inlet；Sensor module is placed in appearance liquid space；Control chip is set on carrier, and is electrically connected sensor module；Wherein, after empty micropin is inserted into human skin, gas is extracted through gas pump, so that holding the vacuum state for forming negative pressure in liquid space, tissue fluid is drawn and enters in the appearance liquid space, detected for sensor module.
Description
Technical field
This case be about a kind of blood sugar detection apparatus, it is espespecially a kind of easy to carry and can painless detection blood glucose blood glucose inspection
Survey device.
Background technique
The diabetic that self is detected as of blood glucose plays a very important role in management blood glucose, but is used at present
The blood glucose machine for measuring blood glucose is all not readily portable, therefore patient is difficult to detect blood-sugar content in outgoing time-varying, and in measurement blood
In the process of sugar, acupuncture treatment is had sometimes but non-bleeding or the very little situation of blood volume, it is therefore desirable to have an acupuncture treatment or firmly squeeze again
Blood out, but acupuncture treatment may cause burden of patients again, and measurement result inaccuracy may be will lead to again by firmly squeezing out blood.
For above-mentioned missing, a kind of safe, easy to carry, painless intelligent blood sugar detection apparatus is developed in this case, is provided
Patient in daily life can at any time, easily measure blood-sugar content, and solve the problems, such as above-mentioned traditional measurement blood glucose.
Summary of the invention
In order to which the blood sugar detection apparatus of solution has the problem of not readily portable, detection misalignment, this case provides a kind of blood glucose inspection
Survey device, include: a carrier has an accommodation groove and a venthole, which is connected with the accommodation groove: a gas pump,
It is set in the accommodation groove and is driven with conduction gas, and an at least air inlet is set, supplied gas by this at least lead by an air inlet
After entering, then by the venthole discharge of the carrier；One waterproof membrane covers an at least air inlet；One microneedle patch, removably
It is attached on the carrier and is covered an at least air inlet, and is communicated with multiple empty micropins and one with multiple empty micropin
Appearance liquid space, at least an air inlet is connected the appearance liquid space with this；One sensor module is placed in the appearance liquid space；With
And one control chip, be set on the carrier, and be electrically connected the sensor module；Wherein, the microneedle patch is multiple hollow
After micropin is inserted into human skin, through control chip controls gas pump driving, by the air inlet gas inlet hole, and make the microneedle patch
The appearance liquid space in form negative pressure state, promote multiple empty micropin to draw the tissue fluid under human skin into the appearance liquid
In space, for blood-sugar content in sensor module detection tissue fluid, to generate a monitoring numerical value.
Detailed description of the invention
Fig. 1 show the schematic diagram of the section structure of the blood sugar detection apparatus of this case.
Fig. 2A show the diagrammatic cross-section of the gas pump of the blood sugar detection apparatus of this case.
Fig. 2 B to Fig. 2 D show the gas pump illustrative view of Fig. 2A.
Fig. 3 show the schematic diagram of the associated components electrical connection relationship of the blood sugar detection apparatus of this case.
Description of symbols
100: blood sugar detection apparatus
1: carrier
11: accommodation groove
111: carrier
112: outlet chamber
12: venthole
2: gas pump
20: air inlet
21: actuated piece
211: outline border
212: vibrating reed
212a: first surface
212b: second surface
212c: protrusion
213: interconnecting piece
214: piezoelectric patches
215: gap
22: resonance plate
221: resonance part
222: fixed part
223: through-hole
23: cover board
231: runner
232: collecting tray
24: glue-line
25: pressure chamber
3: waterproof membrane
4: microneedle patch
41: empty micropin
42: holding liquid space
5: sensor module
51: sensor
52: circuit soft board
6: control chip
7: transmission module
200: external device (ED)
H: spacing
Specific embodiment
The some exemplary embodiments for embodying this case features and advantages will describe in detail in the explanation of back segment.It should be understood that
This case can have various variations in different aspects, all not depart from the range of this case, and explanation therein and diagram
It is inherently illustrated as being used, and nand architecture is in limitation this case.
This case is a kind of blood sugar detection apparatus 100, referring to Fig. 1, blood sugar detection apparatus 100 includes a carrier 1, a gas
Pump 2, one waterproof membrane 3, microneedle patch 4, a sensor module 5 and a control chip 6；One accommodation groove of recessed formation of carrier 1
11, and in a venthole 12 is arranged on carrier 1, for being connected with accommodation groove 11, and gas pump 2 is set in accommodation groove 11, and
Gas pump 2 is provided with an at least air inlet 20, and gas pump 2 is received driving transmission gas and sucked by an at least air inlet 20, then by going out
Stomata 12 is discharged, and waterproof membrane 3 is then to be covered on an at least air inlet 20, and waterproof membrane 3 is a kind of ventilative, waterproof film,
It can so be entered in gas pump 2 with liquid barrier, while gas can not be influenced again and enter gas pump 2；Microneedle patch 4 is detachable
Ground is attached at carrier 11 and covers an at least air inlet 20, and has multiple empty micropins 41 and one and multiple empty micropin 41
The appearance liquid space 42 communicated holds liquid space 42 and is connected with an at least air inlet 20, and sensor module 5 is placed in liquid space 42
It is interior, and control chip 6 is set on carrier 1, and is electrically connected with sensor module 5, it is multiple hollow micro- when microneedle patch 4
Needle 41 is pierced into human skin in noninvasive or minimally invasive mode, at this point, control chip 6 starts the driving of gas pump 2, gas pump 2
Start to execute pumping action, makes to generate negative pressure in the appearance liquid space 42 of microneedle patch 4, it will draw through multiple empty micropin 41
It takes the subcutaneous tissue fluid of human body to enter to hold in liquid space 42, and is located at the sensor module 5 held in liquid space 42 and starts to appearance liquid
Tissue fluid in space 42 is detected, and be will test result and be sent to control chip 6；Sensor module 5 and control chip 6 again
Micro electronmechanical processing procedure (MEMS) can be adopted to be integrated on carrier 1, the two can according to identical system encapsulate be set on carrier 1, but not with
This is limited.Sensor module 5 has further included a sensor 51 and a circuit soft board 52, sensor 51 are set to circuit soft board 52
On, and be connected electrically, then control chip 6 is electrically connected via circuit soft board 52, chip 6 is so controlled to control gas
Detection data measured by pump 2 and reception, analyte sensors module 5.
In addition, above-mentioned microneedle patch 4 is covered on an at least air inlet 20 with being removably attached on carrier 1,
It so can pass through disposable glue-line to be attached on anti-carrier 1, after detection, used microneedle patch 4 can be torn
From on carrier 1, when detecting again, completely new microneedle patch 4 is being pasted, in order to avoid reusing microneedle patch 4, is causing wound
The hygienic issues such as infection, bacterium infection.
Please continue to refer to Fig. 1, the gas pump 2 of the blood sugar detection apparatus 100 of this case is with the actuated piece sequentially stacked
21, the structure that resonance plate 22, cover board 23 are constituted, which is characterized in that actuated piece 21 includes an outline border 211, a vibrating reed
212, multiple interconnecting pieces 213 and a piezoelectric patches 214, outline border 211 is surrounded on the periphery of vibrating reed 212, and penetrates multiple connection
Portion 213 is connected between the two, in addition, be more not connected with through multiple interconnecting piece 213 between vibrating reed 212 and outline border 211
Region is for gas to pass through to constitute multiple gaps 215；Again in this present embodiment, carrier 1 is equipped with carrier 111, for actuated piece
21 outline border 211 is fixed, and the vibrating reed 212 of actuated piece 21 is made to keep gap setting between venthole 12 in accommodation groove 11,
And in forming an outlet chamber 112 between the two, and vibrating reed 212 has the first surface 212a and direction towards venthole 12
The second surface 212b of resonance plate 22, piezoelectric patches 214 are attached at the first surface 212a of vibrating reed 212, and the of vibrating reed 212
Two surface 212b have a protrusion 212c, and protrusion 212c can be integrally formed with vibrating reed 212, and but not limited to this.Resonance
There is piece 22 resonance part 221 and a fixed part 222, resonance part 221 may be disposed at the central area of resonance plate 22, fixed part
222 are formed there through a through-hole 223 in the central area of resonance part 221 for the peripheral edge margin and resonance plate 22 of resonance plate 22,
For gas to pass through, in this present embodiment, through-hole 223 and the protrusion 212c of vibrating reed 212 are vertically opposite；In addition, resonance plate 22
It is stacked and placed on the outline border 211 of actuated piece 21 via fixed part 222, and maintains a spacing h between vibrating reed 212, in the present embodiment
In, it is greater than the thickness of vibrating reed 212 using 211 thickness of outline border of actuated piece 21 to maintain spacing h, can also arranges in pairs or groups simultaneously using glue
Layer 24 uses, or is directly not limited thereto, using the adjustment of glue-line 24, maintenance spacing h so that vibrating reed 212 and resonance plate
A pressure chamber 25 is defined through spacing h between 22.
From the above, an at least air inlet 20 for gas pump 2 is formed on cover board 23, and runs through cover board 23,23 court of cover board
It is formed with an at least runner 231 corresponding with an at least air inlet 20 and a collecting tray 232 to the surface of resonance plate 22, is converged
Chute 232 can be located on same axis with through-hole 223, protrusion 212c；In this present embodiment, air inlet 20 and runner 231 be all
It is 4, but not limited to this, and one end of this 4 runners 231 is respectively communicated in 4 air inlets 20, and the other end is then connection
It, can be each by corresponding runner 231 in collecting tray after promoting gas to enter cover boards 23 by 4 air inlets 20 in collecting tray 232
232 convergences.
After above-mentioned control chip 6 transmits driving voltage to gas pump 2, gas pump 2 starts actuation, please refers to Fig. 2A to figure
2D, Fig. 2A are the diagrammatic cross-section of this case gas pump 2, and Fig. 2 B to Fig. 2 D is the illustrative view of the gas pump 2 of this case, are please first joined
It reads shown in Fig. 2 B, after driving voltage is transmitted to piezoelectric patches 214, piezoelectric patches 214 drives because piezoelectric effect starts to generate deformation
Vibrating reed 212 moves up and down, and first when vibrating reed 212 moves up, and the resonance part 221 of resonance plate 22 can be by Helmholtz
Resonance (Helmholtz resonance) principle moves up, 25 volume of pressure chamber between vibrating reed 212 and resonance plate 22
Become larger, thus generate negative pressure, make the gas outside gas pump 2 start because of the influence of 25 negative pressure of pressure chamber by air inlet 20 into
Enter, is converged by runner 231 corresponding with air inlet 20 then at collecting tray 232, entered finally by the through-hole 223 of resonance plate 22
In pressure chamber 25；Referring again to shown in Fig. 2 C, control 6 continuous transmission driving voltage of chip to gas pump 2, the vibration of actuated piece 21
Movable plate 212 moves down, and the resonance part 221 of resonance plate 22 can be by helmholtz resonance (Helmholtz resonance) at this time
Principle moves down, and reduces the volume of collecting tray 232, so that gas will be pushed into pressure chamber 25 by collecting tray 232, by gas
Body is squeezed into multiple gap 215；Please continue to refer to Fig. 2 D, the vibrating reed 212 of actuated piece 21 is moved upward to initial position, this
When resonance plate 22 resonance part 221 can by helmholtz resonance (Helmholtz resonance) principle move up contact in
Protrusion 212c on vibrating reed 212, and its through-hole 223 is closed simultaneously, at this point, the volume of the collecting tray 232 of cover board 23 increases,
Generate negative pressure, the air for drawing gas pump 2 outside entered into collecting tray 232, and pressure chamber 25 be vibrated the reset of piece 212 and
The influence that resonance part 221 moves up, volume significantly reduce, and generate positive pressure and have the function that squeeze gas, in addition, in
In this step, the through-hole 223 of the protrusion 212c of vibrating reed 212 closing resonance plate 22, while compression pressure chamber 25 can
It avoids back flow of gas from returning collecting tray 232, achievees the effect that non-return, can effectively promote delivery efficiency.
It finally please refers to shown in Fig. 2A again, resonance plate 22 is moved up and down according to helmholtz resonance principle, compression pressure
It is pushed while chamber 25 and enters multiple gaps 215 of actuated piece 21 in the gas in compression chamber 25, passed the gas through multiple
Gap 215 flows into outlet chamber 112 (please referring to Fig. 1), is finally discharged again by venthole 12, constantly defeated through control chip 6
Driving voltage enables 2 continuous transmission gas of gas pump, the appearance liquid space 42 of microneedle patch 4 is caused to be formed roughly to actuated piece 21 out
Vacuum state generates negative pressure, and multiple empty micropins 41 is enabled to enter appearance through negative pressure to draw the tissue fluid under human skin
In liquid space 42, blood-sugar content in the tissue fluid of subcutis is monitored by sensor module 5, and generate a monitoring numerical value.
Multiple empty micropins 41 of above-mentioned microneedle patch 4 are the micron order size pinholes that can pierce through skin, material
It can be high molecular polymer, metal or silicon, preferably to have the silica of high-biocompatibility, the aperture of empty micropin 41 is big
Small is to pass through for insulin molecule, preferably, the internal diameter of empty micropin 41 is empty between 10 microns (μm) to 550 microns (μm)
The length of heart micropin 41 is that can be inserted into the subcutaneous tissue of human body between 400 microns (μm) to 900 microns (μm) and be pierced into depth not
Human nerve is touched, therefore not will cause pain completely.Multiple empty micropins 41 are set in microneedle patch 4 and adopt with array manner
Arrangement, from need to be greater than 200 microns between each empty micropin 41 is adjacent, the unlikely interference for having the water conservancy diversion that influences each other, such battle array
Multiple empty micropins 41 that column mode is arranged, not having a wherein needle empty micropin 41 blocking influences the function of injection fluid, and
It can continue to maintain the function for injecting fluid with other empty micropins 41.
It please refers to shown in Fig. 3, is the block schematic diagram of the element connection relationship of the blood sugar detection apparatus of this case, in this implementation
In example, blood sugar detection apparatus 100 can further include a transmission module 7, control 6 framework of chip on carrier, and with gas pump 2, pass
Sensor module 5, transmission module 7 are electrically connected, and sensor module 5 monitors blood-sugar content in the tissue fluid of subcutis, and
A corresponding monitoring numerical value is generated, it is sent to and controls chip 6, after the monitoring numerical value for controlling 6 receiving sensor 5 of chip, then
It is transferred to transmission module 7, blood-sugar content information is transmitted to an external device (ED) 200 using transmission module 7, and external device (ED) 200
Can for a cloud system, a portable apparatus, a computer system, a display device, an insulin injection device etc. at least its
One of.Wherein, control chip 6 more may include a graphene battery (not shown), and to provide power supply, but not limited to this.
In addition, above-mentioned transmission module 7 can for using wire transmission, such as: USB, mini-USB, micro-USB at least its
One of wire transmission module, or can for using wireless transmission, such as: a Wi-Fi module, a bluetooth module, one wirelessly penetrate
At least one of wireless transport modules such as frequency identification module, a near field communication module.
In conclusion blood sugar detection apparatus provided by this case penetrates after microneedle patch is pierced into the subcutaneous tissue of human body
The internal gas of the appearance liquid space of microneedle patch is drawn in the actuation of gas pump, draws power in holding formation negative pressure in liquid space, so that
Microneedle patch draws the tissue fluid of subcutaneous tissue through multiple empty micropins, then by being located at the sensor module held in liquid space
The blood-sugar content in tissue fluid is detected, to parse blood glucose information, and blood glucose information is transferred to transmission module via control chip,
Know to be supplied to user, and through graphene battery setting, enable the invention to without plug-in can easily, letter
List measures blood glucose anywhere or anytime, reduces the puzzlement that user measures blood glucose, in addition, the present invention uses nothing using microneedle patch
Wound or the minimally invasive generation and drop for detecting blood glucose to obtain the tissue fluid of subcutaneous tissue, user's burden being reduced, avoid wound
Low infection risk.
This case appointed as person familiar with the technology apply craftsman think and be it is all as modify, it is so neither de- such as attached claim
Be intended to Protector.
Claims (15)
1. a kind of blood sugar detection apparatus, includes:
One carrier, has an accommodation groove and a venthole, which is connected with the accommodation groove；
One gas pump is set in the accommodation groove and is driven with conduction gas, and an at least air inlet is arranged, supplied gas by this extremely
After a few air inlet imports, then by the venthole discharge of the carrier；
One waterproof membrane covers an at least air inlet；
One microneedle patch is removably attached on the carrier and covers an at least air inlet, and has multiple empty micropins
And the appearance liquid space that is communicated with multiple empty micropin, at least an air inlet is connected the appearance liquid space with this；
One sensor module is placed in the appearance liquid space；And
One control chip, is set on the carrier, and be electrically connected the sensor module；
Wherein, it after multiple empty micropin insertion human skin of the microneedle patch, is driven through control chip controls gas pump
It is dynamic, by the air inlet gas inlet hole, and make the appearance liquid space of the microneedle patch is interior to form negative pressure state, promotes multiple empty micropin
The tissue fluid drawn under human skin enters in the appearance liquid space, detects blood-sugar content in tissue fluid for the sensor module, with
Generate a monitoring numerical value.
2. blood sugar detection apparatus as described in claim 1, which is characterized in that the sensor module further included a sensor and
One circuit soft board, the sensor are set to the circuit soft board, which is electrically connected the control chip.
3. blood sugar detection apparatus as described in claim 1, which is characterized in that the gas pump has by an actuated piece, a resonance
Piece, a cover board are sequentially stacked and are constituted, and at least an air inlet is formed in the cover board for this.
4. blood sugar detection apparatus as claimed in claim 3, which is characterized in that define a pressure between the actuated piece and the resonance plate
An outlet chamber is defined between the venthole of power chamber and the actuated piece and the carrier.
5. blood sugar detection apparatus as claimed in claim 3, which is characterized in that the cover board is with more an at least runner and a confluence
Slot, at least one end of runner connection corresponding with an at least air inlet, the other end are connected to the collecting tray.
6. blood sugar detection apparatus as claimed in claim 3, which is characterized in that the actuated piece includes a piezoelectric patches and a vibration
Piece, the piezoelectric patches are attached at a first surface of the vibrating reed towards the venthole direction.
7. blood sugar detection apparatus as claimed in claim 6, which is characterized in that the vibrating reed towards the resonance plate direction one
There is a protrusion on two surfaces.
8. blood sugar detection apparatus as described in claim 1, which is characterized in that the blood sugar detection apparatus includes a transmission mould
Block, which is electrically connected the control chip, to link an external device (ED).
9. blood sugar detection apparatus as claimed in claim 8, which is characterized in that the transmission module be a USB, a mini-USB,
At least one of wire transmission module of one micro-USB.
10. blood sugar detection apparatus as claimed in claim 8, which is characterized in that the transmission module is for a Wi-Fi module, one
At least one of wireless transport module of bluetooth module, a radio frequency identification module and a near field communication module.
11. blood sugar detection apparatus as claimed in claim 8, which is characterized in that the external device (ED) is a cloud system, one can take
Formula device, a computer system, a display device, an insulin injection device etc. at least one.
12. blood sugar detection apparatus as described in claim 1, which is characterized in that every in multiple empty micropins of the microneedle patch
One has internal diameter between 10 microns to 550 microns, and length is between 400 microns to 900 microns.
13. blood sugar detection apparatus as described in claim 1, which is characterized in that multiple empty micropin is arranged with array manner,
And adjacent spacing is greater than 200 microns in multiple empty micropin each.
14. blood sugar detection apparatus as described in claim 1, which is characterized in that several empty micropins are with earth silicon material
It is made.
15. blood sugar test value device as described in claim 1, which is characterized in that the control chip further includes graphene electricity
Pond.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711316396.0A CN109907763B (en) | 2017-12-12 | 2017-12-12 | Blood sugar detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711316396.0A CN109907763B (en) | 2017-12-12 | 2017-12-12 | Blood sugar detection device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109907763A true CN109907763A (en) | 2019-06-21 |
| CN109907763B CN109907763B (en) | 2021-11-23 |
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ID=66956639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711316396.0A Active CN109907763B (en) | 2017-12-12 | 2017-12-12 | Blood sugar detection device |
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| CN205626630U (en) * | 2016-03-11 | 2016-10-12 | 成都市亿泰科技有限公司 | Portable injection device of intelligence insulin based on cloud calculates |
| CN106236108A (en) * | 2016-08-30 | 2016-12-21 | 张胜国 | Intelligence Wicresoft blood glucose continuous monitor system |
| CN106974632A (en) * | 2016-01-15 | 2017-07-25 | 研能科技股份有限公司 | Wearable device |
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2017
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|---|---|---|---|---|
| CN1887374A (en) * | 2006-07-27 | 2007-01-03 | 纳生微电子(苏州)有限公司 | Sound wave needle inserting system for micro needle array plaster |
| US20120282138A1 (en) * | 2007-12-10 | 2012-11-08 | Bayer Healthcare Llc | Integrated fluid analyte meter system |
| CN101332327A (en) * | 2008-08-06 | 2008-12-31 | 清华大学 | Micro hollow silicon needle and preparation method thereof |
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| CN109907763B (en) | 2021-11-23 |
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