CN109758644A - A kind of device of synchronous detection blood glucose and insulin injection - Google Patents

A kind of device of synchronous detection blood glucose and insulin injection Download PDF

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Publication number
CN109758644A
CN109758644A CN201910163697.7A CN201910163697A CN109758644A CN 109758644 A CN109758644 A CN 109758644A CN 201910163697 A CN201910163697 A CN 201910163697A CN 109758644 A CN109758644 A CN 109758644A
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injection
piston
injection tube
blood glucose
insulin
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CN109758644B (en
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李晓彤
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Abstract

The invention discloses the devices of a kind of synchronous detection blood glucose and insulin injection, including syringe, the syringe includes the injection tube that syringe needle and one end are connect with syringe needle, the inner cavity front end of the injection tube is provided with the secondary piston comprising mold insert in secondary piston, mold insert is check valve A from back to front in the secondary piston, and the piston after the inner cavity of the injection tube other end is provided with forms back cavity between rear piston and secondary piston, insulin is filled in the back cavity, rear piston is connected with piston driver;The inner cavity front bottom end of injection tube is provided with check valve B from inside to outside, the outer end of the check valve B is provided with plasma glucose detection device.The device can complete blood sugar test and injection of insulin by once having an acupuncture treatment.

Description

A kind of device of synchronous detection blood glucose and insulin injection
Technical field
The present invention relates to medical instruments fields, and in particular to a kind of device of synchronous detection blood glucose and insulin injection.
Background technique
Currently, in the diabetes medicament of whole world TOP10, totally 7 kinds of injectivity insulin product, the sugar of Zhan Quanqiu 50% or so Urinate medicine market (Diabetes Atlas 8th Edition. Abu Dhabi:International Diabetes Federation;2017.).There are about 39,000,000 diabetics for needing to maintain blood glucose level by insulin, these pancreases in China About 70% to 93% people is using novopen (Global Report On Diabetes.Geneva:World in the element user of island Health Organization;2016.).
For the patient using novopen control blood glucose, three times, i.e., one day needs of most of novopen are injected Protamine zine insulin is set to be also required to inject everyday.But current insulin injection pen is mostly Manual mechanical structure, this insulin The pen that the compression bar of injection pen easily damages, has, which only uses 1-2 times, can not just press compression bar, and such product is usually disposable produces Product, so as to cause a large amount of valuable drug wastes.Loss is brought to patient.Furthermore this novopen rotary metering inaccuracy, All whether injection can not be checked intuitively setting injection dosage, and also without completing prompt, injection operation, which relies on compression bar and pushes away, motionless is Standard, once compression bar is in injection, failure, Continued depression will lead to generation broken needle in subcutaneous risk on the way.Especially many glycosurias Patient because with obesity, retinopathy, nervous system lesion etc., correct insulin injection over the long term to they be it is a not Small challenge, once injection is wrong, bring damage is usually very big, the not good enough, hypopsia especially for some hand flexibility ratios Old-aged diabetic more very.
In addition, blood glucose need to be detected daily toward contact for the diabetic for needing to carry out injection of insulin treatment, come Adjust insulin dosage.But in most cases, injection of insulin and survey blood glucose are allocated as two things to complete, often First to survey blood glucose, then insulin injection.But in this process, patient's bleeding that not only needs to have an acupuncture treatment when detecting blood glucose has come It at detection, needs to have an acupuncture treatment again again when insulin injection, which increase the pains of patient, for being easy the patient having a fainting spell during acupuncture treatment More so.At present in addition to the detection mode to plasma glucose, there are also the mode of a kind of pair of tissue fluid blood sugar test, the technical solution Blood glucose detecting head sensor is by up of three-layer: semi-permeable membrane, glucose oxidase and microelectrode (Diabetes Care. 2019; 42 (Suppl. 1): S1-S193.).The glucose sensor of the program be commonly made to it is needle-shaped, be pierced into user it is subcutaneous it Afterwards, the glucose between user's subcutaneous cell in liquid chemically reacts, and utilizes glucose in carbohydrate oxidase and tissue fluid Reaction detects the consumption of reaction process oxygen, is eventually converted into dextrose equivalent (Aged in China diabetes B treatment measure expert Common recognition (version in 2018) [J] China internal medicine will, 2018,57 (9): 630-634).Above-mentioned tissue fluid blood-sugar detection sensor, It has been widely used in many insulin pumps for needing 24 hours monitoring blood glucose and insulin injection, but has still needed in use Blood plasma formula detection device periodic calibration (usually twice a day), patient, which also needs separately to purchase equipment, to calibrate, particularly with amnesia Old user is often easy to forget to calibrate, or simply forgets to carry calibrator (-ter) unit, is inconvenient.
Summary of the invention
Technical problem to be solved by the invention is to provide the devices of a kind of Portable blood sugar detection and injection of insulin.
In order to solve the above technical problems, the technical scheme is that a kind of synchronous detection blood glucose and insulin injection Device, including syringe, the syringe includes the injection tube that syringe needle and one end are connect with syringe needle, in the inner cavity of the injection tube Front end is provided with the secondary piston comprising mold insert in secondary piston, and mold insert is check valve A from back to front in the secondary piston, is injecting The inner cavity of the cylinder other end is provided with rear piston, forms back cavity between rear piston and secondary piston, fills insulin in the back cavity, after Piston is connected with piston driver;The inner cavity front bottom end of injection tube is provided with check valve B from inside to outside, in the list The outer end of valve B is provided with plasma glucose detection device.
Further: the check valve A is spring steel bead structure.
Further: the check valve B is feather valve slice structure.
It is further: supporting plate to be provided with below the check valve B, one end of the elastic valve plate of check valve B is fixedly mounted In injection drum outer wall, the two sides of the elastic valve plate are provided with backplate.
Further: the syringe needle has tissue fluid blood-sugar detection sensor, and the tissue fluid blood-sugar detection sensor connects It is connected to tissue fluid blood sugar detecting unit.
Further: it further includes irregularly-shaped hole, and the special-shaped hole site is in zero be fixedly connected on injection tube or with injection tube On part, the position of irregularly-shaped hole and injection tube are relatively fixed, and the piston driver includes the punching being fixedly connected with injection tube Screw motor, the core through screw rod motor include special spiral rod and the motor body that is threadedly coupled with special spiral rod, the abnormity Screw rod has section compatible with irregularly-shaped hole and passes through irregularly-shaped hole, and one end of special spiral rod is fixedly connected with rear piston.
Further: it further includes controller, and the controller is connected by connecting line with syringe, and controller includes electricity Machine control unit, processor, display screen and control button, the motor control unit is along connecting line and core through screw rod motor phase Even, core through screw rod motor is stepper motor, and the processor is connected with display screen, control button and motor control unit respectively It connects, processor is also connected with injection key.
Further: the processor is connected with networking module.
Further: the plasma glucose detection device includes test paper, the test paper interface being connected with test paper and connects with test paper The connected plasma glucose detection unit of mouth.
By using above-mentioned technical proposal, the solution have the advantages that providing a kind of Portable blood sugar detection and pancreas islet The device of element injection, the device have following technological progress:
1. the present invention combines injection with blood sugar test, realize that pricking a needle completes two functions, kills two birds with one stone, and The integrated structure is relatively simple, it is cheap, be conducive to promote.Which reduce the pains that patient need to originally prick needle twice, especially Suitable for the patient that has a fainting spell during acupuncture treatment.Furthermore insulin dosage can be set according to the blood sugar test value at scene, according to more scientific, and It can addition processing device the case where calculating automatically, saving the process that patient voluntarily calculates, and avoid easy miscalculation.It can also be timely And increase or decrease insulin accurately to match continually changing demand.
Tissue fluid blood sugar detecting method can be used more quickly to detect blood glucose in 2 present invention, and itself has blood plasma blood The function of sugar detection can easily carry out the calibration of tissue fluid blood sugar test, particular avoid user and forget to carry school Quasi- equipment and the relevant risk generated.
3. the present invention is since piston driver uses motor driven, stepper motor etc., which especially can be used, accurately to be driven Motor after, injection dosage and injection process can be precisely controlled.Not only injection process is easily controllable, but also greatly reduces injection The risk hidden danger of process.Injection process takes automatic control, avoids the original bad grasp of one-handed performance pressing dynamics, and compression bar holds The drawbacks of causing high amount of drug waste and injection process not to be easy to happen broken needle intuitively or be injected into muscle layer easy to damage.It is whole A process is simply light, very convenient diabetic, and especially long-term illness or old complication patient use.Greatly mitigate The pain and medical-risk of patient.
4. the present invention has processor, simple program in the prior art can be run to increase data record transfer function, Facilitate patient blood glucose's control and Scientific Usage of Drugs management.The blood glucose value of many patient's measurements does not record continuously, because wanting record Each insulin injection dosage, is a no small trouble for patients.Many patient's insulin injection dosage are by big General estimation, the effect for controlling blood glucose can only be by estimation.Data record transfer function solves sufferer per injection dosage and blood The matched scientific adjustment problem of sugar value, can track and calculate insulin dose, be conducive to grasp sufferer basic data, realize essence Quasi- treatment.
5. processor of the invention can also run the reminder for supervising injection on time, therapeutic effect is improved, and there is language Sound module come for vision disorder crowd provide conveniently.The diabetic middle-aged and the old accounts for significant proportion, self-care ability is poor, amnesia, Dim eyesight, there are great security risks.The elderly has a poor memory, and may can not remember that last time has beaten how much dosage, when beat , beaten does not have on earth.If given another injection, it is easy to appear hypoglycemia;If not beating, blood glucose is lost control of again.The above Situation is extremely disadvantageous to glucostasis.It supervises prompting function patient can be made to inject on time, prevents from repeating or forgetting that injection is brought Risk, improve therapeutic effect.
6. syringe of the invention only integrates the necessary modules such as some piston drivings and sensor, other operations, display It is all integrated in relatively independent controller with part control module or even battery etc., controller and syringe only pass through soft Connecting line connection.The weight with volume of syringe itself in this way greatly reduce, and are conducive to patient and hold injection, reduce because of inconvenience In the broken needle risk that operation generates.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention;
Fig. 2 is the cross-sectional view in Fig. 1 at A-A;
Fig. 3 is functional block diagram of the invention;
Wherein, 1- end cap, 2- inject key, 3- calibration switch, 4- core through screw rod motor, 5- irregularly-shaped hole, 6- dead ring, 7- connection Line, 8- controller, 9- display screen, 10- control button, 11- back cavity, 12- injection tube, 13- secondary piston, mold insert in 14- secondary piston, After 15- check valve elastic component, 16- ante-chamber, 17- syringe needle, 18- bottom outlet, 19- valve, 20- supporting plate, 21- backplate, 22- test paper, 23- Piston, 25- flange, 26- test paper interface, 27- fuselage, 28 sleeves, 29- special spiral rod, 30- are buckled after mold insert, 24- in piston.
Specific embodiment
Illustrate first, is with syringe by person of modern times for syringe and its " forward and backward " of subassembly the two term positions Before the direction of body skin is, otherwise after being.
Such as attached drawing 1 ~ 3, the present invention includes syringe, and the syringe includes that syringe needle 17 and one end are connect with syringe needle 17 Injection tube 12 is provided with the secondary piston 13 comprising mold insert 14 in secondary piston in the inner cavity front end of the injection tube 12, living before described Mold insert 14 is check valve A from back to front in filling in, the piston 24 after the inner cavity of 12 other end of injection tube is provided with, rear piston 24 with Back cavity 11 is formed between secondary piston 13, fills insulin in the back cavity 11, rear piston 24 is connected with piston driver;It is infusing The inner cavity front bottom end of shooting cylinder 12 is provided with check valve B from inside to outside, and the outer end of the check valve B is provided with plasma glucose Detection device.
The overall work process of above scheme is: first before use, piston driver be pushed forward after piston 24, be pushed forward Pressure is transferred to secondary piston 13 by the insulin in back cavity 11.Generally unidirectionally the cracking pressure of valve A can be greater than secondary piston 13 with Frictional force (being Specifically pressure caused by frictional force) between injection tube 12, is on the one hand that people can select between piston and injection tube Both rub relatively small material to produce, the check valve elasticity in check valve A is on the other hand then set up when manufacturing The elastic size of part 15 keeps cracking pressure opposing pistons frictional force larger.Thus the insulin in back cavity 11 reaches a certain pressure Under strong, secondary piston 13 is set to move forward in the case where being not turned on check valve A, until secondary piston 13 is pushed to the bottom of injection tube 12. Later, syringe needle 17 is penetrated into human body, the pulling force of piston 24 after piston driver post-tensioning, post-tensioning passes through the insulin in back cavity 11 It is transferred to secondary piston 13, secondary piston 13 is moved back and forms ante-chamber 16 between injection tube 12.Due to 12 inner cavity front end of injection tube The flow direction of the check valve B of bottom is that from inside to outside, therefore outside air cannot be introduced into ante-chamber 16, and only suck from syringe needle Blood.In addition ante-chamber 16, to avoid this from happening, should control piston driving there is also from the path of 11 inhaled Insulin of back cavity The pulling force of device makes it that secondary piston 13 can be made to generate movement and reach the cracking pressure of check valve A.Additionally due to pancreas Element injection in island need to usually penetrate human body blood and transport less position, to draw the blood that human body slowly oozes out, should not also apply excessive Suction force to cause human body to ooze out a large amount of tissue fluid.Although research shows that the blood sugar concentration difference in tissue fluid and blood is very It is small, for being normally applied no materially affect, but at present in Medical Instruments to the equipment of tissue fluid blood sugar test be required to periodically with Blood testing result is calibrated, therefore the present invention is to guarantee blood sugar test accuracy, is still detected using blood.It is to be pumped to arrive (amount of a drop is only needed for currently used detection technique) after specified blood volume, piston driver is pushed forward rear piston again later The cracking pressure of 24, check valve B should be selected as less than the pressure that blood re-injection is entered to human body, can be by the elasticity member in check valve B Part elasticity is made small, then the blood in ante-chamber 16 is then mainly flow to except injection tube 12 from check valve B, and by check valve B outside The plasma glucose detection device at end detects.
Above-mentioned is blood testing process, is insulin injection procedure later.Due to finally will be to be measured in the above process Blood extrudes except injection tube 12, therefore final secondary piston 13 reaches the bottom of injection tube 12, ante-chamber 16 disappears, and piston drives at this time Device continues to be pushed forward rear piston 24, and the end of secondary piston 13 has sealing syringe needle to this section of path check valve B under thrust Effect, after preventing insulin overflow.Check valve A is finally set to reach cracking pressure after piston driver continues to be pushed forward, So that the insulin in back cavity 11 is injected into syringe needle 17 and then inject human body, stops injection after rated capacity to be achieved.
It need to be intended that, specific value needed for the cracking pressure of above-mentioned check valve A and check valve B, be that view product is specific The selection of correlated parts material, and according to common knowledge through limited trials it can be learnt that.In addition it is also easy to it is found that unidirectional The cracking pressure of valve A is higher, then secondary piston 13 is better to the leakproofness of syringe needle to path between check valve B, and be pushed forward, post-tensioning Occur that a possibility that insulin surprisingly overflows is lower in the process, therefore the cracking pressure of check valve A in the conceived case will be as far as possible Greatly.Additionally, due to before operate during, may within the positions such as check valve B remained blood.It can be grasped after injection Make syringe to take out area and extrude medicinal alcohol quickly to carry out the disinfection of region of interest.
Above-mentioned check valve A and check valve B can use spring steel bead structure, feather valve slice structure can also be used, with And the structure of other any achievable fluid one-way movement functions, but the cracking pressure of check valve A needs are high as far as possible, therefore here Be preferably spring steel bead structure, in spring resilience in comparison valve block for, be easier to obtain biggish coefficient of elasticity, and Its overall structure is again very simple.And due to check valve B needs be arranged on the outer wall of injection tube 12, need it is thin as far as possible, and its Cracking pressure is small as far as possible, therefore is here preferably feather valve slice structure, and the structure of feather valve chip can be made thin relatively, And the cracking pressure of elastic valve plate can be made small.Such as Fig. 1, the specific structure of check valve B of the invention is in injection tube 12 Bottom is provided with the bottom outlet 18 of perforation, in the valve 19 that 18 outer end of bottom outlet has an one end to be adhered to 12 outer wall of injection tube, valve 19 Make it that can usually cover bottom outlet 18 with elasticity, the unlatching when there is fluid to flow outward from bottom outlet 18.To make to gush from valve 19 Drop of blood out will not flow away along the lower outer wall of injection tube 12, and the present invention is also provided with supporting plate 20 in the lower section of valve 19 and carrys out support blood Drop, so that drop of blood be made effectively to touch plasma glucose detection device.It is arranged additionally, due to valve 19 itself in 12 outer wall of injection tube, It is easy it by unexpected collsion damage, therefore the present invention is also provided with the backplate 21 positioned at 19 two sides of valve, to prevent accident It is damaged caused by impact.
Above scheme is that the detection of the plasma glucose of blood drawing formula is first completed by once having an acupuncture treatment, later insulin injection again 's.But since insulin need to be subcutaneously injected, injection site selects blood to transport less region progress substantially, therefore in blood drawing It very slowly, is to shorten the integrated operation time, the outer layer of syringe needle 17 of the invention can integrate semi-permeable membrane, glucose oxidase and micro- Electrode, that is to say, that syringe needle 17 serves not only as injection head, is also simultaneous for tissue fluid blood-sugar detection sensor, tissue fluid blood sugar test Sensor reconnects organized liquid blood sugar detecting unit, sensor signal is converted to blood glucose value.In this way, the present apparatus passes through Few position is transported in blood, and blood sugar test and injection of insulin, and opposite blood drawing detection fast speed are completed by once having an acupuncture treatment. When needing to calibrate tissue fluid blood sugar test after use for several times, then the present apparatus can be pierced into blood and transport preferable position, it is single The plasma glucose detection of blood drawing formula is solely carried out for calibrating.Compared to pervious calibration mode, this avoid users to take The case where 2 kinds of equipment of band could be calibrated smoothly, for person in middle and old age amnesia user, avoids and sets because forgetting to carry calibration Standby and bring injects risk.
Furthermore piston driver of the invention, both can be used can also be used manually it is electronic, but due to the unlatching of check valve A Pressure needs are high as far as possible, and for the patient of for example certain old ages, the strength and the coordination ability of hand can all decline, and be difficult good Good operating syringe, thus piston driver of the invention be it is electronic, to facilitate these special sufferers.Its specific structure is: Including the core through screw rod motor 4 being fixedly connected with injection tube 12, the core through screw rod motor 4, which runs through, a special spiral rod 29, The special spiral rod 29 passes through an irregularly-shaped hole 5 being matched therewith.Irregularly-shaped hole 5 can be located on injection tube 12, but this implementation Example is on the fuselage 27 being fixedly connected with injection tube 12.The position of irregularly-shaped hole 5 is fixed with 12 phase of injection tube, special spiral rod 29 One end be fixedly connected with rear piston 24.It need to be intended that, position and 12 phase of injection tube of irregularly-shaped hole 5 are fixed, and refer in particular to make Used time, irregularly-shaped hole 5 will not generate rotation between injection tube 12, so that rotation will not be generated between core through screw rod motor 4, The hole both can be used as an aperture on the component of fixed injection tube 12, also can be used as a special part and is fixedly mounted on phase Answer position.And core through screw rod motor 4 is the motor that a kind of rotor is hollow swivel nut, and such as Fig. 2 of special spiral rod 29 is one kind two Side has the screw rod of plane, when special spiral rod 29 penetrates core through screw rod motor 4, and passes through a phase not rotated together with motor After answering irregularly-shaped hole 5, make the rotary motion of core through screw rod motor 4, is converted into the linear motion of the forward or backward of special spiral rod 29, from And piston 24 is mobile after driving.The cooperation of screw rod and swivel nut, not only creates the movement for becoming straight line from rotation, also makes the straight line Movement can have biggish motive force, so that thrust be made to be greater than the strength of common manpower, make the cracking pressure of check valve A can be into one Step improves.
Further, core through screw rod motor 4 is stepper motor, then can be by motor control unit (such as model The control chip of TB67S279FTG) revolution of motor is more accurately controlled, so that the amount of movement of piston be made to obtain Control in the case where 12 diameter of injection tube determines, and then obtains the control to extraction amount and injection volume, specifically avoids original Hand equipment is not easy injection volume the disadvantage being precisely controlled and undue force is easy to damage.It is more accurate in order to be carried out to motor Detailed control, the invention also includes controller 8, controller 8 is connected by connecting line 7 with syringe.Due to by control section It is transferred in the controller 8 of separation, the volume weight of syringe can be made to minimize in this way, be conducive to acupuncture treatment operation.Controller 8 Including motor control unit, processor, display screen 9 and control button 10.Motor control unit is along connecting line 7 and core through screw rod electricity Machine 4 is connected, and processor is connected with display screen 9, control button 10 and motor control unit respectively.It is pressed by display screen 9 with control Key 10, user can sets itself injection volume, signal is issued into motor control unit after processor calculates.Above-mentioned processor can be adopted With single-chip microcontroller (for example, by using the single-chip microcontroller of model STM32F0), the embedded system based on ARM framework also can be used, so as to It is with the same function to run that there is the more multi-functional APP(based on Android to change the system of corresponding framework certainly for operation IOS application also can).Processor can be realized by corresponding program periodically reminds detection and injection and long-term record detection and injection Data.In addition processor can be connected with networking module, and wifi networking module can be used in networking module, but moves to more adapt to user It is dynamic, using 4G networking module more preferably (for example, by using the networking module of model U8300C).The present apparatus can be with server after networking It is connected with smart machines such as user mobile phones, so that can judge patient health situation using big data technology in server end, realizes Precisely medical treatment;And on the smart machine of user terminal, the previous data detected with injection of display can be summarized by corresponding APP, side Just user query, and detection can be carried out to client by smart machine and inject prompting, because the smart machines such as mobile phone are relatively more It is frequently accompanied by user, so that being not easy to be missed by the prompting that smart machine issues.
For the volume and weight for further mitigating syringe, the battery powered to each electrical component should also be placed in controller 8 In.
Additionally, due to the sequence of operations of the invention that inject again that needs first to be drawn blood when in use, to simplify patient's manipulation, It may be provided with injection key 2, injection key 2 is connect with processor, and patient carries out by pressing the key to be controlled by processor Subsequent sequence of operations, the key are to be preferably mounted on syringe convenient for operation.
In addition, controller 8 of the invention can also include voice module.The chip of voice module can use JQ8900- 16P reconnects outside speaker.After increasing voice module, it can be convenient the user having defective vision and use, such as dim eyesight Middle-older patient, it can broadcast the relevant information on display screen 9, and voice can also be carried out when proceeding to steps necessary It reminds, such as informs that user can pull out needle after injection.It need to be intended that, the voice module necessarily uses sentence complete At prompting function, such as using simply piping or musical sound is prompted also may be used.
Now widely used electric pole type test paper detection device can be used in plasma glucose detection device in above scheme. The detection of electric pole type test paper is the mainstream detection method of current blood glucose meter, this detection device technology maturation, cheap, in addition by Belong to electrochemical process in the detection, compared to the means using photochemical method, it is not necessary that optic probe is arranged in test paper incoming end, it is only necessary to It is provided with electrode, therefore the test paper interface 26 with electrode can be fixedly mounted on the injector, to be inserted into test paper 22, remaining What is be connected with test paper interface can be placed in controller 8 as blood sugar test and the plasma glucose detection unit of calculating, to reduce The volume and weight of syringe facilitate the injection of patient to grasp and do.The plasma glucose detection unit is connected with processor, can also benefit Blood glucose is shown with display screen 9 above-mentioned, and a recommendation injection volume can be intelligently determined according to current blood glucose amount, or current On the basis of blood glucose recommends injection volume, one preform injection amount (such as blood glucose after the meal is further added by by control button 10 by patient When not rising to peak completely also).In addition for increasing the scheme of organized liquid blood sugar test, tissue fluid blood sugar test list Member should also be placed in controller 8 and be connected with processor, tissue fluid blood sugar detecting unit and tissue fluid blood-sugar detection sensor it Between line by syringe fuselage and connecting line 7, to make syringe only integrate necessary operational module, to reduce whole Volume and weight is more advantageous to grip and operation.Additionally due to the number that the numerical value and plasma glucose of tissue fluid blood sugar test detect Value finally all converges in processor, corrects after calibrating operation is voluntarily compared by processor, simplifies user's operation.
Since the overall cost of syringe is relatively high, therefore after the insulin in injection tube 12 has all been injected, need more Injection tube 12 is changed to improve equipment recycling rate of waterused.Its specific structure is: such as Fig. 1, core through screw rod motor 4 passes through fuselage 27 and note Shooting cylinder 12 is fixedly connected, and injection tube 12 is provided with flange 25 in the one end connecting with fuselage 27, injection tube 12 be also cased with block it is convex The dead ring 6 of edge 25, dead ring 6 are connect by screw thread pair with fuselage 27.In addition, having in rear piston 24 tapped rear living Mold insert in filling in, the internal screw thread can be threadedly engaged with special spiral rod 29.In addition, test paper interface 26 should also be fixedly connected on fuselage 27 On.
When dismantling old injection tube 12, it is unclamped with fuselage 27 by rotational fastener ring 6, thereafter rotary injection cylinder 12, Screw out rear piston 24 from special spiral rod 29, to complete to be detached from.When installing new injection tube 12, special spiral rod 29 is made to contract It is back to regulation most weakness, then rear piston 24 screws in special spiral rod 29 by way of rotary injection cylinder 12, wait be threaded into injection After the bleeding position of contact fuselage 27 and 12 end of injection tube substantially of cylinder 12 is also aligned with plasma glucose detection device, pass through screw thread Adjutant's fuselage 27 and dead ring 6 fasten, so that injection tube 12 be fixed.It is above-mentioned make special spiral rod 29 be retracted to regulation it is most short During place, to make the shortest distance be easy to grasp, it can be reduced to maximum stroke in special spiral rod 29, calibration switch 3 is set. Special spiral rod 29 once triggers the switch, then motor stops contractive action.Certainly, except detachably being tied described in the present embodiment Structure, other quick detachable replaceable structures, the structures such as revotating card button, controllable pawl type are equally applicable to the present invention, only Reach the function that injection tube 12 is field-replaceable unit.
Additionally while the fixing means of core through screw rod motor 4 and fuselage 27 can be varied, this reality once is described in detail again here Apply the specific structure of example: such as Fig. 1, fuselage 27 is a tubular structure, and lower end plane is provided with irregularly-shaped hole 5, and motor is by upper port It is put into, since the casing of the core through screw rod motor 4 of this example has flat horizontal surface, the inner cavity of fuselage 27 also has same shape, makes electricity Machine is caught in it to prevent motor from generating circumferential sliding in rotation.Furthermore it is fixed motor, sleeve is packed into above motor 28, the top of sleeve 28 can resist end cap 1, thus the lengthwise position of fixed motor.End cap 1 and fuselage 27 are connected by buckle 30 It connects.

Claims (10)

1. a kind of device of synchronous detection blood glucose and insulin injection, it is characterised in that: including syringe, the syringe includes The injection tube (12) that syringe needle (17) and one end are connect with syringe needle (17), is provided in the inner cavity front end of the injection tube (12) and includes The secondary piston (13) of mold insert (14) in secondary piston, mold insert (14) is check valve A from back to front in the secondary piston, in injection tube (12) inner cavity of the other end is provided with rear piston (24), forms back cavity (11) between rear piston (24) and secondary piston (13), described Insulin is filled in back cavity (11), rear piston (24) is connected with piston driver;In the inner cavity front bottom end of injection tube (12) It is provided with check valve B from inside to outside, the outer end of the check valve B is provided with plasma glucose detection device.
2. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 1, it is characterised in that: the list It is spring steel bead structure to valve A.
3. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 1, it is characterised in that: the list It is feather valve slice structure to valve B.
4. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 3, it is characterised in that: the list It being provided with below to valve B supporting plate (20), one end of the elastic valve plate of check valve B is fixedly installed in injection tube (12) outer wall, The two sides of the elastic valve plate are provided with backplate (21).
5. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 1, it is characterised in that: the needle Head (17) has tissue fluid blood-sugar detection sensor, and the tissue fluid blood-sugar detection sensor is connected with tissue fluid blood sugar test list Member.
6. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 1, it is characterised in that: further include Irregularly-shaped hole (5), the irregularly-shaped hole (5) be located on injection tube (12) or the part that is fixedly connected with injection tube (12) on, irregularly-shaped hole (5) position and injection tube (12) are relatively fixed, and the piston driver includes the punching being fixedly connected with injection tube (12) Screw motor (4), the core through screw rod motor (4) include special spiral rod (29) and the motor that is threadedly coupled with special spiral rod (29) Main body, the special spiral rod (29) have the compatible section with irregularly-shaped hole (5) and pass through irregularly-shaped hole (5), special spiral rod (29) One end be fixedly connected with rear piston (24).
7. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 6, it is characterised in that: it is also wrapped Include controller (8), the controller (8) is connected by connecting line (7) with syringe, controller (8) include motor control unit, Processor, display screen (9) and control button (10), the motor control unit is along connecting line (7) and core through screw rod motor (4) phase Even, core through screw rod motor (4) be stepper motor, the processor respectively with display screen (9), control button (10) and motor control Unit is connected, and processor is also connected with injection key (2).
8. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 7, it is characterised in that: the control Device (8) processed further includes voice module, and the voice module is connected with processor.
9. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 7, it is characterised in that: the place Reason device is connected with networking module.
10. the device of a kind of synchronous detection blood glucose and insulin injection according to claim 1, it is characterised in that: described Plasma glucose detection device includes test paper (22), the test paper interface (26) being connected with test paper (22) and is connected with test paper interface (26) Plasma glucose detection unit.
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