CN109901648A - A kind of control method of gel pre-encapsulated injector final sterilization system - Google Patents
A kind of control method of gel pre-encapsulated injector final sterilization system Download PDFInfo
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- CN109901648A CN109901648A CN201711310614.XA CN201711310614A CN109901648A CN 109901648 A CN109901648 A CN 109901648A CN 201711310614 A CN201711310614 A CN 201711310614A CN 109901648 A CN109901648 A CN 109901648A
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Abstract
The invention discloses a kind of control methods of gel pre-encapsulated injector final sterilization system, belong to biological instrument field, the control method of gel pre-encapsulated injector final sterilization system of the invention, it is slowly entered by saturation pure steam, cold air is discharged by gland steam exhauster in cabinet simultaneously, the steam displacement being repeated several times in this way, is to the last all replaced by saturation pure steam, the requirement of sterilizing is reached using the thermal energy of pure steam.
Description
[technical field]
The present invention relates to a kind of control methods of gel pre-encapsulated injector final sterilization system.
[background technique]
The prior art is: its sterilizing of pulse vacuum pressure-steam sterile cabinets is to be gone out by vacuum pump by the flowing extraction of water
Bacterium cabinet cold air inside, is at negative pressure state, and then input saturation heat steam, quickly penetrates into it inside article, such as
This is 3 times or 4 times repeatedly.Make microprotein denaturation solidification under the action of high temperature and high pressure power and inactivates and reach sterilizing and want
It asks, pulse vacuum pressure-steam sterile cabinets have the stroke vacuumized, the rubber plug and gel of pre-encapsulated injector can be extracted out, destroy
Product.It cannot function as the final sterilization of gel pre-encapsulated injector.
[summary of the invention]
The technical problem to be solved by the present invention is to provide a kind of control method of gel pre-encapsulated injector final sterilization system,
Reach excellent sterilization effect.
In order to solve the above technical problems, the present invention adopts the following technical scheme:
A kind of control method of gel pre-encapsulated injector final sterilization system, the gel pre-encapsulated injector finally go out
Fungus strain system includes pulse vacuum pressure-steam sterile cabinets, control system and pipe-line system, the pulse vacuum pressuresteam sterilization
Cabinet includes cabinet and the collet that is arranged in cabinet, and the pipe-line system includes that connection pulse vacuum pressure-steam sterile cabinets are used for
Into the pure steam pipeline of saturation pure steam, for the blow-off line of exhaust and for the air compression pipeline into pneumatics, the pure steam
Pipeline includes the first branch for connecting cabinet and the second branch of connection collet, and the first branch is equipped with the first solenoid valve,
The second branch is equipped with second solenoid valve, and the blow-off line is equipped with third solenoid valve, and the air compression pipeline is equipped with the 4th electricity
Magnet valve, is equipped with temperature detector and pressure detector in the pulse vacuum pressure-steam sterile cabinets, first solenoid valve, the
Two solenoid valves, third solenoid valve, the 4th solenoid valve, temperature detector connect control system, the controlling party with pressure detector
Method the following steps are included:
(1) temperature rise period, the 4th solenoid valve first on air compression pipeline are in close state, the third electricity on blow-off line
Magnet valve is closed, and the first solenoid valve and second solenoid valve are opened from pure steam pipeline into saturation pure steam, the first solenoid valve after 1-25S
It is closed with second solenoid valve, third solenoid valve is opened from exhaust pipe and the intracorporal cold air of case is discharged, and 5-10 is repeated the above process
After secondary, the third solenoid valve on blow-off line is closed, and the first solenoid valve and second solenoid valve interval are opened and closed, until temperature detector
Temperature in detection box reaches the setting sterilising temp in control system；
(2) sterilization phase, the first solenoid valve are in close state, when pressure is less than control in pressure detector detection collet
When the minimum pressure set in system, the second solenoid valve in second branch is opened into pure steam in often collet, when pressure is examined
When pressure is greater than the maximum pressure set in control system in survey device detection collet, second solenoid valve is closed, until control system
The sterilizing stroke of setting terminates；
(3) exhaust phase, second solenoid valve are in close state, and the 4th solenoid valve interval on air compression pipeline is opened and closed toward arteries and veins
Compressed air is returned in dynamic vacuum pressure steam sterilization cabinet, meanwhile, the 4th solenoid valve interval opening and closing discharge pneumatics on blow-off line
With the mixed gas of steam, until pressure detector detects pressure < | 0.02 | MPa, the temperature in temperature detector detection box
96 DEG C of <.
Further, during first solenoid valve of temperature rise period and second solenoid valve interval are opened and closed, the first solenoid valve
2-25S is closed after opening 0.1-10S with second solenoid valve.
Further, minimum pressure is 0.105-0.110Mpa, maximum pressure 0.109- in the sterilization phase
0.115Mp。
Further, in the exhaust phase, the 4th solenoid valve on air compression pipeline opens 0.3-3S, meanwhile, gland steam exhauster
The 4th solenoid valve on road opens 1-10S.
Beneficial effects of the present invention:
The control method of inventive gel pre-encapsulated injector final sterilization system, is slowly entered, together by saturation pure steam
When cabinet in cold air be discharged by gland steam exhauster, the displacement of the steam that is repeated several times in this way is to the last all taken by saturation pure steam
In generation, reaches the requirement of sterilizing using the thermal energy of pure steam.1) in entirely sterilizing stroke, the vacuum pump of disinfection system is always not
Work, will not generate negative pressure, ensure that the pressure in pulse vacuum pressure-steam sterile cabinets is relative constant.2) in the temperature rise period,
The discharge of pure steam slowly entered with cold air to reach heating purpose, while ensure that sterilizing using gravity principle,displacement
Pressure in cabinet cabinet 11 is constant.3) sterilization phase, pure steam enter pulse vacuum steam sterilization cabinet collet 12, to guarantee to sterilize
Temperature and pressure in cabinet cabinet 11.4) temperature-fall period is that pneumatics slowly enters the heat of sterilizing cabinet dilution pure steam to reach
Cooling guarantees the constant of sterilizing cabinet pressure.
These features and advantages of the invention will the detailed exposure in following specific embodiment, attached drawing.
[Detailed description of the invention]
Following further describes the present invention with reference to the drawings:
Fig. 1 is the structural diagram of the present invention；
Fig. 2 is the principle of the present invention figure.
[specific embodiment]
The technical solution of the embodiment of the present invention is explained and illustrated below with reference to the attached drawing of the embodiment of the present invention, but under
Stating embodiment is only the preferred embodiment of the present invention, and not all.Based on the implementation example in the implementation mode, those skilled in the art
Member's obtained other embodiments without making creative work, belong to protection scope of the present invention.
Referring to fig. 1 and fig. 2, a kind of gel pre-encapsulated injector final sterilization system, gel pre-encapsulated injector is most
Whole disinfection system includes pulse vacuum pressure-steam sterile cabinets, control system 3 and pipe-line system, pulse vacuum pressuresteam sterilization
Cabinet includes cabinet 11 and the collet 12 that is arranged in cabinet 11, and pipe-line system includes that connection pulse vacuum pressure-steam sterile cabinets are used
In into saturation pure steam pure steam pipeline 21, for the blow-off line 22 of exhaust and for the air compression pipeline 23 into pneumatics, it is pure
Jet chimney 21 is including connecting the first branch 211 of cabinet 11 and connecting the second branch 212 of collet 12, in the first branch 211
Equipped with the first solenoid valve 41, the second branch 212 is equipped with second solenoid valve 42, and blow-off line 22 is equipped with third solenoid valve 43,
Air compression pipeline 23 is equipped with the 4th solenoid valve 44, is equipped with temperature detector 51 and pressure detecting in pulse vacuum pressure-steam sterile cabinets
Device 52, the first solenoid valve 41, second solenoid valve 42, third solenoid valve 43, the 4th solenoid valve 44, temperature detector 51 and pressure inspection
It surveys device 52 and connects control system 3, control system 3 is according to the detection signal of temperature detector 51 and pressure detector 52 control first
Solenoid valve 41, second solenoid valve 42, third solenoid valve 43, the 4th solenoid valve 44.
A kind of control method of gel pre-encapsulated injector final sterilization system the following steps are included:
(1) temperature rise period, first the 4th solenoid valve 44 on air compression pipeline 23 are in close state, on blow-off line 22
Third solenoid valve 43 is closed, and the first solenoid valve 41 and second solenoid valve 42 are opened from pure steam pipeline 21 into saturation pure steam, is made
Temperature is to raise simultaneously in collet 12 and cabinet 11, and the first solenoid valve 41 and second solenoid valve 42 are closed after 1-25S, third electromagnetism
Valve 43 is opened from the cold air in exhaust pipe discharge cabinet 11, after repeating the above process 5-10 times, temperature in cabinet 11 by
Edge up height；Then the third solenoid valve 43 on blow-off line 22 is closed, and the first solenoid valve 41 and second solenoid valve 42 are intermittently opened and closed,
Preferred first solenoid valve 41 and second solenoid valve 42 close 2-25S after opening 0.1-10S, air inlet increasing temperature and pressure slow in this way,
Until the temperature in 51 detection box 11 of temperature detector reaches the setting sterilising temp in control system 3；
(2) sterilization phase, the first solenoid valve 41 are in close state, when pressure is small in the detection collet 12 of pressure detector 52
When the minimum pressure set in control system 3, the second solenoid valve 42 in second branch 212 is opened in often collet 12 into pure
Steam, when pressure is greater than the maximum pressure set in control system 3 in the detection collet 12 of pressure detector 52, second solenoid valve
42 close, until the sterilizing stroke that control system 3 is set terminates, to guarantee that pressure is relative constant in cabinet 11, that is, guarantee
Gel pre-encapsulated injector external and internal pressure it is relative constant, be ensuring that peace of the gel pre-encapsulated injector under sterilizing state
Entirely；The minimum pressure preferably set is 0.105-0.110Mpa, maximum pressure 0.109-0.115Mp.
(3) exhaust phase, second solenoid valve 42 are in close state, and 44 interval of the 4th solenoid valve on air compression pipeline 23 is opened
It closes and returns compressed air in pulse vacuum pressure-steam sterile cabinets, to dilute the steam heat in collet 12 and cabinet 11, meanwhile,
The 4th solenoid valve 44 on blow-off line 22 is intermittently opened and closed the mixed gas of discharge pneumatics and steam, so slowly cooling, drop
Pressure, gel pre-encapsulated injector external and internal pressure are in relative constant state, until pressure detector 52 detects pressure < | and 0.02 |
MPa, 96 DEG C of temperature < in 51 detection box 11 of temperature detector, Exhaust stroke terminates, and sterilizing is completed.Wherein air compression pipeline 23
On the 4th solenoid valve 44 open 0.3-3S, meanwhile, the 4th solenoid valve 44 on blow-off line 22 opens 1-10S.
Through the foregoing embodiment, the purpose of the present invention is completely and effectively reached.One of ordinary skilled in the art
It should be understood that the present invention including but not limited to attached drawing and above content described in specific embodiment.It is any without departing from the present invention
The modification of function and structure principle be intended to be included in the range of claims.
Claims (4)
1. a kind of control method of gel pre-encapsulated injector final sterilization system, it is characterised in that: the pre- encapsulating note of gel
Emitter final sterilization system includes pulse vacuum pressure-steam sterile cabinets, control system and pipe-line system, the pulse vacuum pressure
Power steam sterilization cabinet includes cabinet and the collet that is arranged in cabinet, and the pipe-line system includes connection pulse vacuum steam
Sterilizing cabinet is used for the pure steam pipeline into saturation pure steam, the blow-off line for exhaust and for the air compression pipeline into pneumatics,
The pure steam pipeline includes the first branch for connecting cabinet and the second branch of connection collet, and the first branch is equipped with the
One solenoid valve, the second branch are equipped with second solenoid valve, and the blow-off line is equipped with third solenoid valve, and the air compression pipeline is set
There is the 4th solenoid valve, is equipped with temperature detector and pressure detector in the pulse vacuum pressure-steam sterile cabinets, described first
Solenoid valve, second solenoid valve, third solenoid valve, the 4th solenoid valve, temperature detector connect control system with pressure detector, institute
State control method the following steps are included:
(1) temperature rise period, the 4th solenoid valve first on air compression pipeline are in close state, the third solenoid valve on blow-off line
It closes, the first solenoid valve and second solenoid valve are opened from pure steam pipeline into saturation pure steam, the first solenoid valve and the after 1-25S
Two solenoid valves are closed, and third solenoid valve is opened from exhaust pipe and the intracorporal cold air of case is discharged, after repeating the above process 5-10 times,
Third solenoid valve on blow-off line is closed, and the first solenoid valve and second solenoid valve interval are opened and closed, until temperature detector detects
Temperature in cabinet reaches the setting sterilising temp in control system；
(2) sterilization phase, the first solenoid valve are in close state, when pressure is less than control system in pressure detector detection collet
When the minimum pressure of middle setting, the second solenoid valve in second branch is opened in often collet into pure steam, works as pressure detector
When pressure is greater than the maximum pressure set in control system in detection collet, second solenoid valve is closed, until control system is set
Sterilizing stroke terminate；
(3) exhaust phase, second solenoid valve are in close state, and the 4th solenoid valve interval on air compression pipeline is opened and closed true toward pulsation
Compressed air is returned in empty pressure-steam sterile cabinets, meanwhile, the 4th solenoid valve interval opening and closing discharge pneumatics and steaming on blow-off line
The mixed gas of vapour, until pressure detector detects pressure < | 0.02 | MPa, the temperature < 96 in temperature detector detection box
℃。
2. the control method of gel pre-encapsulated injector final sterilization system as claimed in claim 1, it is characterised in that: the heating
During the first solenoid valve of stage and second solenoid valve interval are opened and closed, after the first solenoid valve and second solenoid valve open 0.1-10S
Close 2-25S.
3. the control method of gel pre-encapsulated injector final sterilization system as claimed in claim 1, it is characterised in that: the sterilizing
Minimum pressure is 0.105-0.110Mpa, maximum pressure 0.109-0.115Mp in stage.
4. the control method of gel pre-encapsulated injector final sterilization system as claimed in claim 1, it is characterised in that: the exhaust
In stage, the 4th solenoid valve on air compression pipeline opens 0.3-3S, meanwhile, the 4th solenoid valve on blow-off line opens 1-10S.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711310614.XA CN109901648B (en) | 2017-12-11 | 2017-12-11 | Control method of final sterilization system of gel pre-filled and sealed syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711310614.XA CN109901648B (en) | 2017-12-11 | 2017-12-11 | Control method of final sterilization system of gel pre-filled and sealed syringe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109901648A true CN109901648A (en) | 2019-06-18 |
| CN109901648B CN109901648B (en) | 2021-02-09 |
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ID=66942685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711310614.XA Active CN109901648B (en) | 2017-12-11 | 2017-12-11 | Control method of final sterilization system of gel pre-filled and sealed syringe |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112168985A (en) * | 2020-10-10 | 2021-01-05 | 山东新华医疗器械股份有限公司 | Pre-filling needle sterilization production line and production method |
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| CN106039334A (en) * | 2016-06-30 | 2016-10-26 | 张家港华菱医疗设备股份公司 | Pre-filling needle sterilizer and sterilizing method thereof |
| CN106729793A (en) * | 2017-01-19 | 2017-05-31 | 张家港欧思瑞医疗科技有限公司 | A kind of prefilled syringe sterilizing cabinet |
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Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05131019A (en) * | 1991-08-02 | 1993-05-28 | Osaka Gas Co Ltd | Method and device for sterilization and desinfection |
| US5869000A (en) * | 1997-06-20 | 1999-02-09 | Johnson & Johnson Medical, Inc. | Partial vapor removal through exhaust port |
| CN200954517Y (en) * | 2006-09-12 | 2007-10-03 | 李瑞菊 | Disinfecting destroying device for disposable medical nursing articles |
| CN101690824A (en) * | 2009-10-12 | 2010-04-07 | 张家港市华菱医疗设备制造有限公司 | On-line sterilizer of damp and hot vapour sterilization cabinet |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112168985A (en) * | 2020-10-10 | 2021-01-05 | 山东新华医疗器械股份有限公司 | Pre-filling needle sterilization production line and production method |
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| CN109901648B (en) | 2021-02-09 |
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