CN109892655A - A kind of asparagus oral liquor and preparation method thereof - Google Patents
A kind of asparagus oral liquor and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to Chinese herbal medicine beverage technical field, a kind of asparagus oral liquor and preparation method thereof is proposed.A kind of asparagus oral liquor, including 450~570 parts of asparagus, 18~35 parts of ginseng, 5~30 parts of ganoderma lucidum, 1~5 part of structure Qi, 19~40 parts of honeysuckle, 10~20 parts of chrysanthemum, 3~8 parts of Radix Notoginseng, 6~18 parts of pseudo-ginseng, 8~26 parts of radix scutellariae, 15~35 parts of coptis root, 7~23 parts of Radix Rehmanniae, 3~12 parts of Radix Angelicae Sinensis, 40~60 parts of Fructus Forsythiae, 18~53 parts of Radix Isatidis, 0.5~1 part of ginkgo, 0.2~0.7 part of hydrolyzed wheat protein, 0.1~0.8 part of glycine betaine, 0.01~0.1 part of disodium 5 '-ribonucleotide, 0.02~0.05 part of sodium glutamate, 0.3~1 part of natrium malicum, 0.5~2 part of honey, preparation method, including first Chinese herbal medicine is crushed, it impregnates, boiling, hydrolyzed wheat protein is added after filtering, glycine betaine, The raw materials such as disodium 5 '-ribonucleotide, sodium glutamate, natrium malicum, honey, it is filling by homogeneous, ultraviolet sterilization and etc. after mixing.Through the above technical solutions, solving the problems, such as that asparagus oral liquor stability is poor in the prior art, standing time is short.
Description
Technical field
The invention belongs to Chinese herbal medicine beverage technical field, it is related to a kind of asparagus oral liquor and preparation method thereof.
Background technique
Asparagus also known as reed point, selaginella doederlleini, mountain asparagus fern, Lilium tenuifolium etc. are the tender shoots of grass family perennial herb reed.It is former
- one band of Mediterranean is produced, there is cultivation on the ground such as existing China Shandong, Zhejiang, Henan, Beijing.Asparagus vitamin B rich in, dimension
The raw element microelements such as A and folic acid, selenium, iron, manganese, zinc, have various amino acid necessary to human body, have diuresis, prevent
Vascular sclerosis inhibits the multiple efficacies such as hypertension, pre- anti-cancer, is increasingly absorbed in by people and payes attention to.
Asparagus product currently on the market is mostly the primary processed items such as canned asparagus spear, cold storing and fresh-keeping asparagus, quick-frozen asparagus,
Added value of product is not high.In recent years, the understanding with people to asparagus health value, Asparagus Industry will obtain big development,
Development potentiality is huge in terms of asparagus intensive processing.
Chinese patent " CN1059263A " discloses a kind of method of preparing asparagus oral liquor, and asparagus raw material is selected and cleans
After squeeze out juice, add flavoring agent and be filtered after adjusting pH value, refiltered after adding auxiliary material to deploy and stir.Carry out Ultramicro-powder
Tank bag after broken, high-temperature short-time sterilization, cooling and be made, the preparation method is simple, can retain the original local flavor of asparagus, but the mouth
Take that liquid stability is bad, and standing time is short.
Summary of the invention
The present invention proposes a kind of asparagus oral liquor and preparation method thereof, solves asparagus oral liquor stability in the prior art
Problem poor, standing time is short.
The technical scheme of the present invention is realized as follows:
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
It is 450~570 parts of asparagus, 18~35 parts of ginseng, 5~30 parts of ganoderma lucidum, 1~5 part of structure Qi, 19~40 parts of honeysuckle, yellow
Spend 10~20 parts, 3~8 parts of Radix Notoginseng, 6~18 parts of pseudo-ginseng, 8~26 parts of radix scutellariae, 15~35 parts of coptis root, 7~23 parts of Radix Rehmanniae, Radix Angelicae Sinensis 3
~12 parts, 40~60 parts of Fructus Forsythiae, 18~53 parts of Radix Isatidis, 0.5~1 part of ginkgo, 0.2~0.7 part of hydrolyzed wheat protein, glycine betaine
0.1~0.8 part, 0.01~0.1 part of disodium 5 '-ribonucleotide, 0.02~0.05 part of sodium glutamate, 0.3~1 part of natrium malicum, honey
0.5~2 part.
As further technical solution, it is grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, pseudo-ginseng
10 parts, 15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, wheat water
0.5 part of albumen of solution, 0.5 part of glycine betaine, 0.05 part of disodium 5 '-ribonucleotide, 0.03 part of sodium glutamate, 0.6 part of natrium malicum, honey 1.3
Part.
The invention also provides a kind of preparation methods of asparagus oral liquor, comprising the following steps:
S1. according to a kind of formula of above-mentioned asparagus oral liquor, each component is weighed, it is spare；
S2. by asparagus, ginseng, ganoderma lucidum, structure Qi, honeysuckle, chrysanthemum, Radix Notoginseng, pseudo-ginseng, radix scutellariae, coptis root, Radix Rehmanniae, Radix Angelicae Sinensis, company
Stick up, Radix Isatidis, ginkgo mix, and smash it through 200 meshes, obtain just mixed object；
S3. the secondary distilled water of its 5 times of quality is added into the first mixed object that step S1 is obtained, is risen while stirring after immersion
The first filter residue and the first filtrate is obtained by filtration after stopping stirring in temperature, spare；
S4. the secondary distilled water of its 3 times of quality is added to the filter residue that step S3 is obtained, warming while stirring stops stirring
After the second filter residue and the second filtrate is obtained by filtration, it is spare；
S5. it is concentrated after the second filtrate that the first obtained filtrate of step S3 and step S4 obtain being mixed, obtains concentrate；
S6. hydrolyzed wheat protein, glycine betaine, disodium 5 '-ribonucleotide, paddy ammonia are sequentially added in the concentrate obtained to step S5
Sour sodium, natrium malicum, honey, obtain mixed material after mixing；
S7. mixed material step S6 obtained successively carries out first time homogeneous and second of homogeneous at 60 DEG C, obtains
Material after homogeneous；
S8. the material after homogeneous step S7 obtained carries out sterilization filling, obtains a kind of asparagus oral liquor.
As further technical solution, soaking time is 10~20min in step S3.
As further technical solution, warming while stirring continues after stirring 20min, stops to 100 DEG C in step S4
Stirring.
As further technical solution, warming while stirring continues to stop after stirring 20min to 100 DEG C in step S4
Stirring.
As further technical solution, concentration is specially to be concentrated under reduced pressure in step S5, be concentrated into density be 1.05~
1.10g/mL。
As further technical solution, incorporation time is 20~30min in step S6.
As further technical solution, first time homogenization pressure is 25MPa in step S7, and second of homogenization pressure is
30MPa。
As further technical solution, sterilizing is ultraviolet sterilization, sterilization time 15min in step S8.
It the working principle of the invention and has the beneficial effect that
1, it in the present invention, using asparagus as primary raw material, is cooperateed with traditional Chinese medicinal components other in formula and wheat hydrolyzes egg
The component compatibilities such as white, glycine betaine, disodium 5 '-ribonucleotide, sodium glutamate, natrium malicum, honey, the raw material of specific proportion and preparation side
Method is all that inventor pays a large amount of painstaking effort researchs and obtains, each component in entire formula cooperates, and plays mutual increasing
The effect of effect and collaboration, so that the asparagus oral liquor of preparation not only has good fungistatic effect and immunoregulation capability, significantly
The immunity of body is improved, and stability is good, standing time is longer, highly-safe, it is taste, good in taste, play expectation
Less than effect.
2, in the present invention, using asparagus as traditional Chinese medicinal components compatibilities other in primary raw material, with formula, so that the asparagus mouthful of preparation
Liquid is taken with good inhibitory anti-virus effect, significantly improves the immunity of body.It is antibacterial disease-resistant using asparagus as monarch drug in a prescription in formula
Poison, Radix Isatidis, Radix Rehmanniae, honeysuckle, coptis root, ginkgo be ministerial drug, anti-inflammatory toxin expelling, improve immunity of organisms, ginseng, ganoderma lucidum, chrysanthemum,
It baikal skullcap root be used as the adjuvant medicine, strengthening the spleen and stomach, tonifying Qi promotes body operating, improves the premunition of body, structure Qi, Radix Angelicae Sinensis, Radix Notoginseng, pseudo-ginseng are
Make medicine, benefiting blood and regulating blood circulation, clearing heat and promoting fluid further increases the anti-virus ability of body, and various ingredients compatibility plays antibacterial anti-jointly
Virus, the effect of Immune-enhancing effect.
3, in the present invention, hydrolyzed wheat protein and glycine betaine cooperate, and improve the stability of asparagus oral liquor, so that
The asparagus oral liquor stability of preparation is more preferable, and standing time is longer.Disodium 5 '-ribonucleotide is matched with sodium glutamate, natrium malicum, honey
5, the mouthfeel and taste of asparagus oral liquor are improved, so that the asparagus oral liquor of preparation more meets the mouthfeel demand of consumer, tool
There is good practical value.
4, the present invention in, preparation method will first be added after Chinese herbal medicine crushing, immersion, boiling, filtering hydrolyzed wheat protein,
The raw materials such as glycine betaine, disodium 5 '-ribonucleotide, sodium glutamate, natrium malicum, honey, after mixing by homogeneous, ultraviolet sterilization etc.
Step makes each component mixing in formula more evenly, preferably play the synergistic effect of each component in formula, so that preparation
Asparagus oral liquor stability while inhibitory anti-virus effect is good is more preferable, safety is higher, and mouthfeel is more preferable, and suitable popularization makes
With.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
Embodiment 1
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
450 parts of asparagus, 18 parts of ginseng, 5 parts of ganoderma lucidum, 1 part of structure Qi, 19 parts of honeysuckle, 10 parts of chrysanthemum, 3 parts of Radix Notoginseng, pseudo-ginseng 6
Part, 8 parts of radix scutellariae, 15 parts of coptis root, 7 parts of Radix Rehmanniae, 3 parts of Radix Angelicae Sinensis, 40 parts of Fructus Forsythiae, 18 parts of Radix Isatidis, 0.5 part of ginkgo, wheat hydrolyzes egg
White 0.2 part, 0.1 part of glycine betaine, 0.01 part of disodium 5 '-ribonucleotide, 0.02 part of sodium glutamate, 0.3 part of natrium malicum, 0.5 part of honey,
Preparation method includes the following steps:
S1. according to above-mentioned formula, each component is weighed, it is spare；
S2. by asparagus, ginseng, ganoderma lucidum, structure Qi, honeysuckle, chrysanthemum, Radix Notoginseng, pseudo-ginseng, radix scutellariae, coptis root, Radix Rehmanniae, Radix Angelicae Sinensis, company
Stick up, Radix Isatidis, ginkgo mix, and smash it through 200 meshes, obtain just mixed object；
S3. the secondary distilled water of its 5 times of quality is added into the first mixed object that step S1 is obtained, impregnates the back 10~20min
Stirring side is warming up to 100 DEG C, continues to stop stirring after stirring 20min, the first filter residue and the first filtrate is obtained by filtration, spare；
S4. the secondary distilled water of its 3 times of quality is added to the filter residue that step S3 is obtained, warming while stirring to 100 DEG C, after
Stop stirring after continuous stirring 25min, the second filter residue and the second filtrate is obtained by filtration, it is spare；
S5. being concentrated under reduced pressure into density after the second filtrate that the first obtained filtrate of step S3 and step S4 obtain being mixed is
1.05~1.10g/mL obtains concentrate,
S6. hydrolyzed wheat protein, glycine betaine, disodium 5 '-ribonucleotide, paddy ammonia are sequentially added in the concentrate obtained to step S5
Sour sodium, natrium malicum, honey, 20~30min of mixing obtain mixed material to being uniformly mixed；
S7. mixed material step S6 obtained successively carries out first time homogeneous and second of homogeneous at 60 DEG C, and first
Secondary homogenization pressure is 25MPa, and second of homogenization pressure is 30MPa, the material after obtaining homogeneous；
S8. filling after the material progress ultraviolet sterilization 15min after homogeneous step S7 obtained, it is oral to obtain a kind of asparagus
Liquid.
Embodiment 2
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
570 parts of asparagus, 35 parts of ginseng, 30 parts of ganoderma lucidum, 5 parts of structure Qi, 40 parts of honeysuckle, 20 parts of chrysanthemum, 8 parts of Radix Notoginseng, pseudo-ginseng
18 parts, 26 parts of radix scutellariae, 35 parts of coptis root, 23 parts of Radix Rehmanniae, 12 parts of Radix Angelicae Sinensis, 60 parts of Fructus Forsythiae, 53 parts of Radix Isatidis, 1 part of ginkgo, wheat hydrolysis
0.7 part of albumen, 0.8 part of glycine betaine, 0.1 part of disodium 5 '-ribonucleotide, 0.05 part of sodium glutamate, 1 part of natrium malicum, 2 parts of honey,
Preparation method is the same as embodiment 1.
Embodiment 3
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
480 parts of asparagus, 20 parts of ginseng, 10 parts of ganoderma lucidum, 2 parts of structure Qi, 25 parts of honeysuckle, 12 parts of chrysanthemum, 4 parts of Radix Notoginseng, pseudo-ginseng 8
Part, 11 parts of radix scutellariae, 19 parts of coptis root, 10 parts of Radix Rehmanniae, 5 parts of Radix Angelicae Sinensis, 43 parts of Fructus Forsythiae, 26 parts of Radix Isatidis, 0.6 part of ginkgo, wheat hydrolysis
0.3 part of albumen, 0.3 part of glycine betaine, 0.03 part of disodium 5 '-ribonucleotide, 0.03 part of sodium glutamate, 0.5 part of natrium malicum, honey 0.9
Part,
Preparation method is the same as embodiment 1.
Embodiment 4
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
550 parts of asparagus, 30 parts of ginseng, 25 parts of ganoderma lucidum, 4 parts of structure Qi, 35 parts of honeysuckle, 18 parts of chrysanthemum, 7 parts of Radix Notoginseng, pseudo-ginseng
15 parts, 20 parts of radix scutellariae, 31 parts of coptis root, 19 parts of Radix Rehmanniae, 10 parts of Radix Angelicae Sinensis, 56 parts of Fructus Forsythiae, 47 parts of Radix Isatidis, 0.9 part of ginkgo, wheat water
0.6 part of albumen of solution, 0.7 part of glycine betaine, 0.08 part of disodium 5 '-ribonucleotide, 0.04 part of sodium glutamate, 0.9 part of natrium malicum, honey 1.7
Part,
Preparation method is the same as embodiment 1.
Embodiment 5
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
530 parts of asparagus, 28 parts of ginseng, 17 parts of ganoderma lucidum, 3 parts of structure Qi, 32 parts of honeysuckle, 16 parts of chrysanthemum, 6 parts of Radix Notoginseng, pseudo-ginseng
13 parts, 17 parts of radix scutellariae, 28 parts of coptis root, 16 parts of Radix Rehmanniae, 8 parts of Radix Angelicae Sinensis, 52 parts of Fructus Forsythiae, 39 parts of Radix Isatidis, 0.8 part of ginkgo, wheat water
0.4 part of albumen of solution, 0.6 part of glycine betaine, 0.07 part of disodium 5 '-ribonucleotide, 0.03 part of sodium glutamate, 0.8 part of natrium malicum, honey 1.6
Part,
Preparation method is the same as embodiment 1.
Embodiment 6
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, pseudo-ginseng
10 parts, 15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, wheat water
0.5 part of albumen of solution, 0.5 part of glycine betaine, 0.05 part of disodium 5 '-ribonucleotide, 0.03 part of sodium glutamate, 0.6 part of natrium malicum, honey 1.3
Part,
Preparation method is the same as embodiment 1.
Comparative example 1
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, pseudo-ginseng
10 parts, 15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, nucleotide
0.05 part of disodium, 0.03 part of sodium glutamate, 0.6 part of natrium malicum, 1.3 parts of honey,
Preparation method is corresponding to delete hydrolyzed wheat protein, glycine betaine in step S6, remaining step is the same as embodiment 1.
Comparative example 2
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, pseudo-ginseng
10 parts, 15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, wheat water
0.5 part of albumen of solution, 0.5 part of glycine betaine, 0.03 part of sodium glutamate, 1.3 parts of honey,
Preparation method is corresponding to delete step S6 nucleotide disodium, natrium malicum, remaining step is the same as embodiment 1.
Comparative example 3
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, pseudo-ginseng
10 parts, 15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, wheat water
0.5 part of albumen of solution, 0.5 part of glycine betaine, 0.05 part of disodium 5 '-ribonucleotide, 0.6 part of natrium malicum,
Preparation method is corresponding to delete step S6 Glutamic Acid sodium, honey, remaining step is the same as embodiment 1.
Comparative example 4
A kind of asparagus oral liquor is grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, pseudo-ginseng
10 parts, 15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, wheat water
0.5 part of albumen of solution, 0.5 part of glycine betaine, 0.05 part of disodium 5 '-ribonucleotide, 0.03 part of sodium glutamate, 0.6 part of natrium malicum, honey 1.3
Part,
Preparation method is corresponding to delete step S7, remaining step is the same as embodiment 1.
Each component parts by weight are shown in Table 1 in the formula of the asparagus oral liquor of Examples 1 to 6 and comparative example 1~4:
Each component parts by weight in the formula of the asparagus oral liquor of 1 Examples 1 to 6 of table and comparative example 1~4
Note :-indicate no this item
The asparagus oral liquor prepared to Examples 1 to 6 and comparative example 1~4 is tested for the property, and test experiments are as follows:
1, accelerated stability test:
Referring to the regulation of " Chinese Pharmacopoeia " (2015 editions), asparagus oral liquor prepared by Examples 1 to 6 and comparative example 1~4
It being respectively placed in Brown Glass Brown glass bottles and jars only, sealing is placed 6 months under the conditions of (30 ± 2) DEG C, relative humidity (60 ± 5) %, respectively at
0,1,2,3 and 6 the end of month sampling, Indexs measure the results are shown in Table 2:
Asparagus oral liquor accelerated stability test result prepared by 2 Examples 1 to 6 of table and comparative example 1~4
From Table 2, it can be seen that the asparagus oral liquor of Examples 1 to 6 preparation is after placing 6 months, appearance keeps saturating
Bright, there is no layering, muddiness, flocculation and drug precipitation phenomenon, stability is good.And asparagus prepared by comparative example 1 and comparative example 4
Oral solution start to occur after placing 3 months it is muddy, have drug precipitation phenomenon, it is muddy after placing 6 months, be layered, have part wadding
Solidifying, stability is poor, and asparagus oral liquor prepared by comparative example 2 and comparative example 3 also starts muddy, comparison occur after placing 6 months
Lack hydrolyzed wheat protein and glycine betaine in example 1, disodium 5 '-ribonucleotide, natrium malicum have been lacked in comparative example 2, has been lacked in comparative example 3
Lack sodium glutamate and honey, lacks homogenizing step in the preparation step of comparative example 4, illustrate that formula and preparation method of the invention make
What must be prepared is more preferable with asparagus oral liquor stability, and standing time is longer, lacks wherein any one component, all can be to asparagus mouthful
The stability for taking liquid has an impact.
2, safety testing
Method: white mouse 55,20 ± 5g of weight are taken, stochastic averagina is divided into 11 groups, and every group 5, sub-cage rearing is that is, normal right
According to group, embodiment group and comparative example group.It is daily after on-test, Normal group intragastric administration on mice physiological saline, embodiment group
Only, comparative example group distinguishes prepared by stomach-filling comparative example 1~4 to each 0.5mL of asparagus oral liquor of stomach-filling Examples 1 to 6 preparation respectively
Only, 3 months by a definite date, every group was randomly selected 2 mouse to each 0.5mL of asparagus oral liquor, and weighing, cervical dislocation is put to death, and was dissected immediately, greatly
Body observes the organs such as brain, the heart, kidney, lung, liver, stomach and intestines, and is saved into the further light microscopic of row and perspective electron microscope inspection.
As a result: daily with physiological saline stomach-filling mouse and the asparagus oral liquor and comparative example 1~4 with Examples 1 to 6 preparation
The asparagus oral liquor stomach-filling mouse of preparation is compared, and after 3 months, 11 groups of the weight of animals do not have significant difference, and gross anatomy is shown, right
According to group, embodiment group and comparative example group, hair, eyes, tooth, brain tissue, esophagus, stomach and intestine, liver and gallbladder, heart, kidney etc. are had no
It is abnormal, illustrate that the use of the asparagus oral liquor of preparation of the embodiment of the present invention is safe.
3, subjective appreciation is tested:
Method: selecting 10 smell and the more sensitive subjective appreciation person of the sense of taste, by the way of first hearing and tasting afterwards, respectively to reality
It applies the asparagus oral liquor that example 1~6 and comparative example 1~4 obtain and carries out taste, mouthfeel marking, scoring criterion is 1~10, and taste is got over
It is fresh, mouthfeel is better, then score is higher, conversely, then score is lower, marking situation is shown in Table 3:
The asparagus oral liquor results of sensory evaluation that 3 Examples 1 to 6 of table and comparative example 1~4 obtain
| Group | Taste | Mouthfeel | It is comprehensive |
| Embodiment 1 | 9.26 | 9.22 | 9.25 |
| Embodiment 2 | 9.32 | 9.31 | 9.29 |
| Embodiment 3 | 9.27 | 9.34 | 9.32 |
| Embodiment 4 | 9.34 | 9.46 | 9.39 |
| Embodiment 5 | 9.29 | 9.38 | 9.34 |
| Embodiment 6 | 9.43 | 9.51 | 8.47 |
| Comparative example 1 | 8.19 | 8.27 | 8.23 |
| Comparative example 2 | 6.83 | 8.31 | 7.55 |
| Comparative example 3 | 8.41 | 7.16 | 7.48 |
| Comparative example 4 | 8.33 | 8.04 | 8.21 |
As can be seen from Table 3, the asparagus oral liquor of Examples 1 to 6 preparation is for subjective appreciation committee member, taste
Road, mouthfeel and synthesis are superior to comparative example 1~4 at 9 points or more, illustrate the asparagus oral liquor of preparation of the embodiment of the present invention
Taste, good in taste, in comparison, it is optimum embodiment of the present invention that asparagus oral liquor score prepared by embodiment 6 is higher.
Wherein, the taste of the asparagus oral liquor of comparative example 2 is poor, and the asparagus oral liquor mouthfeel of comparative example 3 is poor, illustrates nucleotide two
The addition of sodium, natrium malicum, significantly improves the taste of asparagus oral liquor, and the addition of sodium glutamate, honey significantly improves reed
The mouthfeel of bamboo shoot oral solution, hydrolyzed wheat protein, glycine betaine, disodium 5 '-ribonucleotide, natrium malicum, sodium glutamate and honey phase interworking
It closes, more meets the mouth of consumer so that the asparagus oral liquor mouthfeel of preparation, taste are more preferable with the traditional Chinese medicinal components compatibility in formula
Sense demand.
4, biocidal property is tested
Asparagus oral liquor prepared by Examples 1 to 6 and comparative example 1~4 is placed on to the culture medium of coating Escherichia coli respectively
On, 37 DEG C are cultivated 24 hours, and it sees whether occur inhibiting bacterium circle, the results are shown in Table 4:
As can be seen from Table 4, Examples 1 to 6 preparation asparagus oral liquor antibacterial circle diameter much larger than comparison 1~
4, illustrate the antibacterial of the asparagus oral liquor that the biocidal property of asparagus oral liquor prepared by the embodiment of the present invention is more preferable, prepared by embodiment 6
Loop diameter is maximum, is optimum embodiment of the present invention.Wherein, the antibacterial circle diameter of comparative example 2 is minimum, illustrates disodium 5 '-ribonucleotide, apple
The addition of tartaric acid sodium also significantly improves asparagus oral liquor while improving the stability and mouthfeel of asparagus oral liquor
Biocidal property plays unexpected effect.
5, the influence test to immunity function
Taking white mouse 60,20 ± 5g of weight, conventinal breeding 3 days, stochastic averagina is divided into 2 groups, and every group 30, sub-cage rearing,
I.e. Normal group, experimental group group and.After on-test, Normal group intragastric administration on mice physiological saline, experimental group stomach-filling are implemented
The asparagus oral liquor of the preparation of example 6 each 0.5mL, for three days on end.Test 3 weeks by a definite date, during which mouse is freely eaten and drinks water, respectively
The 0th after on-test, 7,14,21 days, every group is randomly selected 5 mouse, weighing, and blood sampling of docking, after blood sampling at cervical dislocation
Extremely, thymus gland, spleen are won rapidly and is weighed, and calculating Thymus and Spleen index, (result is with organ weight/weight (mg/g) table
Show), test result see the table below.
5 mouse thymus index (mg/g) of table
| Group | 0th day | 7th day | 14th day | 21st day |
| Normal group | 4.36 | 4.58 | 4.79 | 4.93 |
| Embodiment group | 4.39 | 4.71 | 4.96 | 5.27 |
From table 3 it is observed that embodiment group and comparative example group mouse thymus index are above Normal group, illustrate reed
After bamboo shoot oral solution stomach-filling mouse, the thymus index of mouse is significantly improved, therefore, immunoenhancement result is more preferable.
6 mouse spleen index (mg/g) of table
| Group | 0th day | 7th day | 14th day | 21st day |
| Normal group | 3.47 | 3.56 | 3.64 | 3.66 |
| Embodiment group | 3.50 | 3.72 | 3.96 | 4.29 |
As can be seen from Table 4, embodiment group and comparative example group mouse spleen index are above Normal group, illustrate to use
After asparagus oral liquor stomach-filling mouse, the index and spleen index of mouse is significantly improved, therefore, immunoenhancement result is more preferable.
Thymus gland is the important central immune organ of body, is the major organs of body lymphocyte differentiation and maturation, and spleen
Dirty is the most important peripheral lymphoid organs of body.After lymphocyte is reached maturity in thymus gland, spleen is transferred to through the circulatory system
It is stored in lymphoid tissues dirty and at different levels and lymphoid organ, and finally plays immunization.Thymus and spleen index is body spleen
Dirty and thymus development degree an important reflection, to after intragastric administration on mice asparagus oral liquor, the thymus gland that can significantly improve mouse refers to
Several and index and spleen index shows that asparagus oral liquor promotes the growth and development of mouse spleen and thymus gland, and then enhances immunity of organism.Together
When, the Thymus and Spleen index of embodiment group mouse is all remarkably higher than Normal group, illustrates prepared by the embodiment of the present invention
Asparagus oral liquor have good immunoregulation effect, improve immunity of organisms.
The above is merely preferred embodiments of the present invention, be not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of asparagus oral liquor, which is characterized in that be grouped as by the group of following parts by weight:
450~570 parts of asparagus, 18~35 parts of ginseng, 5~30 parts of ganoderma lucidum, 1~5 part of structure Qi, 19~40 parts of honeysuckle, chrysanthemum 10
~20 parts, 3~8 parts of Radix Notoginseng, 6~18 parts of pseudo-ginseng, 8~26 parts of radix scutellariae, 15~35 parts of coptis root, 7~23 parts of Radix Rehmanniae, Radix Angelicae Sinensis 3~12
Part, 40~60 parts of Fructus Forsythiae, 18~53 parts of Radix Isatidis, 0.5~1 part of ginkgo, 0.2~0.7 part of hydrolyzed wheat protein, glycine betaine 0.1
~0.8 part, 0.01~0.1 part of disodium 5 '-ribonucleotide, 0.02~0.05 part of sodium glutamate, 0.3~1 part of natrium malicum, honey 0.5~
2 parts.
2. a kind of asparagus oral liquor according to claim 1, which is characterized in that be grouped as by the group of following parts by weight:
500 parts of asparagus, 25 parts of ginseng, 15 parts of ganoderma lucidum, 3 parts of structure Qi, 30 parts of honeysuckle, 15 parts of chrysanthemum, 5 parts of Radix Notoginseng, 10 parts of pseudo-ginseng,
15 parts of radix scutellariae, 25 parts of coptis root, 15 parts of Radix Rehmanniae, 7 parts of Radix Angelicae Sinensis, 50 parts of Fructus Forsythiae, 35 parts of Radix Isatidis, 0.7 part of ginkgo, hydrolyzed wheat protein
0.5 part, 0.5 part of glycine betaine, 0.05 part of disodium 5 '-ribonucleotide, 0.03 part of sodium glutamate, 0.6 part of natrium malicum, 1.3 parts of honey.
3. a kind of preparation method of asparagus oral liquor, which comprises the following steps:
S1. the formula of a kind of asparagus oral liquor according to claim 1 or 2 weighs each component, spare；
S2. by asparagus, ginseng, ganoderma lucidum, structure Qi, honeysuckle, chrysanthemum, Radix Notoginseng, pseudo-ginseng, radix scutellariae, coptis root, Radix Rehmanniae, Radix Angelicae Sinensis, Fructus Forsythiae,
Radix Isatidis, ginkgo mix, and smash it through 200 meshes, obtain just mixed object；
S3. the secondary distilled water of its 5 times of quality is added into the first mixed object that step S1 is obtained, warming while stirring after immersion stops
The first filter residue and the first filtrate is obtained by filtration after only stirring, it is spare；
S4. the secondary distilled water of its 3 times of quality is added to the filter residue that step S3 is obtained, warming while stirring stops mistake after stirring
Filter obtains the second filter residue and the second filtrate, spare；
S5. it is concentrated after the second filtrate that the first obtained filtrate of step S3 and step S4 obtain being mixed, obtains concentrate；
S6. sequentially added in the concentrate obtained to step S5 hydrolyzed wheat protein, glycine betaine, disodium 5 '-ribonucleotide, sodium glutamate,
Natrium malicum, honey, obtain mixed material after mixing；
S7. mixed material step S6 obtained successively carries out first time homogeneous and second of homogeneous at 60 DEG C, obtains homogeneous
Material afterwards；
S8. the material after homogeneous step S7 obtained carries out sterilization filling, obtains a kind of asparagus oral liquor.
4. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that soaking time in step S3
For 10~20min.
5. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that in step S4 while stirring
100 DEG C are warming up to, continues after stirring 20min, stops stirring.
6. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that in step S4 while stirring
100 DEG C are warming up to, continues after stirring 25min, stops stirring.
7. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that be concentrated in step S5 specific
To be concentrated under reduced pressure, being concentrated into density is 1.05~1.10g/mL.
8. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that incorporation time in step S6
For 20~30min.
9. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that in step S7 for the first time
Matter pressure is 25MPa, and second of homogenization pressure is 30MPa.
10. a kind of preparation method of asparagus oral liquor according to claim 3, which is characterized in that sterilizing in step S8 is
Ultraviolet sterilization, sterilization time 15min.
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| KR20170137564A (en) * | 2016-06-03 | 2017-12-13 | 주식회사 엘지생활건강 | Composition for improving skin condition comprising herb extracts mixture |
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