CN109865046B - External plaster for treating postpartum body pain and preparation method thereof - Google Patents
External plaster for treating postpartum body pain and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an externally applied ointment for treating postpartum pain of body and a preparation method thereof, the prescription comprises twelve traditional Chinese medicines, motherwort is taken as monarch drug, Chinese angelica, safflower, twotooth achyranthes root, Szechuan lovage rhizome and pseudo-ginseng are taken as ministerial drugs, baical skullcap root, wrinkled gianthyssop herb, eucommia bark and common curculigo rhizome are taken as adjuvant drugs, green tangerine peel and nutgrass galingale rhizome are taken as conductant drugs, the twelve traditional Chinese medicines are decocted into ointment by linseed oil and vaseline ointment in a decocting pot, and the ointment is spread on non-woven fabrics to prepare the externally applied ointment. Through the mutual matching of monarch, minister, assistant and guide in the twelve medicines, the respective effects of the single medicines are exerted, more importantly, the synergistic effect of the medicines in the formula is improved, the efficacy of the medicines is promoted integrally, and the effect of the formula in treating postpartum body pain is enhanced.
Description
Technical Field
The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to an externally applied ointment for treating postpartum body pain and a preparation method thereof.
Background
The unique prescription for treating postpartum body pain and the external ointment with obvious curative effect are not available in the existing medical drugs for treating postpartum body pain.
Disclosure of Invention
The invention aims to provide an external plaster which takes achyranthes root, baical skullcap root, Chinese angelica, wrinkled gianthyssop herb, safflower, sanchi, nutgrass galingale rhizome, Szechuan lovage rhizome, motherwort herb, green tangerine peel, eucommia bark and common curculigo rhizome as main formulas, and the plaster has the effect of treating the postpartum pain of women.
In order to achieve the purpose, the invention provides a formula of an externally applied ointment for treating postpartum body pain, which comprises the following components in parts by weight:
90-120 parts of achyranthes bidentata; 62-80 parts of rhizoma cyperi;
88-118 parts of scutellaria; 75-95 parts of ligusticum wallichii;
88-110 parts of angelica; 120 portions and 160 portions of motherwort;
85-130 parts of agastache rugosus; 47-70 parts of green tangerine orange peel;
90-165 parts of safflower; 80-132 parts of eucommia;
100 portions of notoginseng and 135 portions; 65-85 parts of rhizoma curculiginis;
the twelve traditional Chinese medicine components are calculated according to dry weight;
the ointment formula also comprises 2970 and 4200 parts of siritch; 495 portions of vaseline paste and 700 portions of vaseline paste.
In the formula of the external plaster for treating postpartum body pain, the formula with better treatment effect is as follows: the ointment formula comprises the following components in parts by weight:
100 portions of achyranthes bidentata; 75-80 parts of rhizoma cyperi;
99-109 parts of scutellaria; 75-90 parts of ligusticum wallichii;
88-110 parts of angelica; 130 portions and 155 portions of motherwort;
85-110 parts of agastache rugosus; 48-70 parts of green tangerine orange peel;
95-160 parts of safflower; 80-130 parts of eucommia;
115 parts of pseudo-ginseng and 125 parts of sand; 70-85 parts of rhizoma curculiginis;
the twelve traditional Chinese medicine components are calculated according to dry weight;
the formula of the ointment also comprises linseed oil, and the dosage of the linseed oil is three times of the sum of the weights of all the components by weight;
the ointment formula also comprises vaseline paste, and the dosage of the vaseline paste is half of the sum of the weights of all the components except the linseed oil.
The external plaster for treating postpartum body pain with better effect in the formula also comprises the following components in parts by weight:
100 portions and 105 portions of achyranthes bidentata; 75-78 parts of rhizoma cyperi;
99-105 parts of scutellaria baicalensis; 80-85 parts of ligusticum wallichii;
95-100 parts of angelica; 140 portions of motherwort and 150 portions;
100 portions of agastache rugosus and 105 portions of agastache rugosa; 55-60 parts of green tangerine peel;
125 portions of safflower and 135 portions; 100 portions of eucommia bark and 115 portions;
115 parts of pseudo-ginseng and 120 parts of sand; 70-80 parts of rhizoma curculiginis;
the twelve traditional Chinese medicine components are calculated according to dry weight;
the formula of the ointment also comprises linseed oil, and the dosage of the linseed oil is three times of the sum of the weights of all the components by weight;
the ointment formula also comprises vaseline paste, and the dosage of the vaseline paste is half of the sum of the weights of all the components except the linseed oil.
The preparation method of the external plaster for treating postpartum body pain comprises the following steps:
(1) cleaning and drying Achyranthis radix, rhizoma Cyperi, Scutellariae radix, rhizoma Ligustici Chuanxiong, radix Angelicae sinensis, herba Leonuri, herba Agastaches, pericarpium Citri Reticulatae viride, Carthami flos, Eucommiae cortex, Notoginseng radix and rhizoma Curculiginis respectively, pulverizing into 200 mesh fine powder of 180 meshes respectively, weighing various medicinal powders, and mixing the twelve medicinal powders according to formula ratio to obtain mixed medicinal powder;
(2) adding oleum Sesami weighed in proportion into a decocting pan in advance, adding the mixed medicinal powder into the decocting pan, heating, controlling the temperature of the materials at 70-80 deg.C, stirring, heating and stirring for 30min, adding vaseline, heating and stirring for 20min to obtain paste;
(3) spreading the ointment on non-woven fabric, and cutting into ointment tablet.
The preparation method can adopt the following specific operations in the step (3): filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
The technical solution of the present invention is further explained below.
In the twelve traditional Chinese medicines of the formula, motherwort is taken as a main medicine (monarch medicine), in the clinical medical practice of the traditional Chinese medicine, motherwort is one of the most commonly used traditional Chinese medicines for gynecology, and the motherwort is considered by the traditional Chinese medicine to have the special effect of promoting blood circulation to regulate menstruation and has the efficacy of treating postpartum lochiorrhea, dysmenorrhea, arthralgia and bodily pain.
The invention also takes angelica, safflower, achyranthes, rhizoma ligustici wallichii and pseudo-ginseng as ministerial drugs. According to traditional Chinese medicine, the angelica has the effects of promoting blood circulation to remove blood stasis, tonifying blood and regulating menstruation to relieve pain and enhancing immunity; carthami flos has effects of promoting blood circulation, dredging channels, removing blood stasis, relieving pain, and treating puerperal lochiorrhea, blood stasis pain, blood stasis, and puerperal diseases; achyranthis radix has effects of dispelling blood stasis, dredging channels, and treating puerperal blood stasis, lumbago, knee pain, and osteodynia; rhizoma Ligustici Chuanxiong has effects of promoting blood circulation, dispelling blood stasis, promoting qi circulation, resolving stagnation, dispelling pathogenic wind and relieving pain; notoginseng radix has effects of stopping bleeding, removing blood stasis, relieving swelling and pain, and can be used for treating joint and general pain caused by puerperal dizziness and lochiorrhea.
The invention takes scutellaria, agastache, eucommia and curculigo rhizome as adjuvant drugs. The Scutellariae radix has effects of invigorating qi, replenishing blood, clearing heat, lowering fire, and removing dampness and heat; herba Agastaches has effects of dredging channels, promoting blood circulation, and stopping diarrhea; cortex Eucommiae has effects of nourishing liver and kidney, strengthening tendons and bones, and treating soreness of waist and knees; curculigo orchioides has the effects of warming kidney yang, strengthening bones and muscles and treating cold arthralgia of waist and feet and arthralgia and myalgia.
The invention takes green tangerine orange peel and nutgrass galingale rhizome as guiding drugs. The traditional Chinese medicine considers that the green tangerine peel has the effects of dredging channels, activating blood, promoting qi circulation and relieving pain; xiang is accompanied with the actions of unblocking meridians, regulating qi and alleviating pain.
According to the traditional Chinese medicine formula theory and clinical application, the mutual cooperation of various medicines of monarch, minister, assistant and guide in each group of formula is very important. The invention not only exerts the respective effects of single medicines, but also more importantly improves the synergistic effect of the medicines in the formula, integrally mobilizes the efficacy of the medicines and enhances the effect of the formula on treating postpartum body pain by the mutual matching of monarch, minister, assistant and guide in the twelve medicines.
The invention adopts the form of a Chinese medicinal plaster and adopts a method of externally sticking the plaster to treat the postpartum body pain. The reason is that the twelve traditional Chinese medicine raw materials of the invention, such as achyranthes root, safflower, curculigo orchioides, nutgrass galingale rhizome, Szechuan lovage rhizome and the like, have good effects of stimulating the menstrual flow, invigorating the blood circulation and relieving pain, but the traditional Chinese medicines have strong medicinal properties and are not suitable for being orally taken by puerperae with weak bodies. For lying-in women, the patch is externally pasted, namely the mode of picking the patch to deliver medicine is safer.
Compared with the prior art, the invention has at least the following beneficial effects: the formula of the external plaster for treating postpartum body pain is formed by twelve traditional Chinese medicine raw materials, the activity of various raw materials can be enhanced, fewer raw materials can achieve a remarkable treatment effect through the synergistic effect of medicines, and the external plaster is particularly suitable for external preparations, and is good in compliance of puerpera to medicines, safe, reliable and free of side effect.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Cleaning Achyranthis radix, rhizoma Cyperi, Scutellariae radix, rhizoma Ligustici Chuanxiong, radix Angelicae sinensis, herba Leonuri, herba Agastaches, pericarpium Citri Reticulatae viride, Carthami flos, Eucommiae cortex, Notoginseng radix, and rhizoma Curculiginis with clear water, air drying, and pulverizing into 200 mesh fine powder respectively; preparing enough oleum Sesami and vaseline.
Example 1
Weighing 90g of achyranthes bidentata, 70g of rhizoma cyperi, 88g of scutellaria baicalensis, 80g of ligusticum wallichii, 95g of angelica sinensis, 140g of leonurus, 100g of agastache rugosus, 60g of pericarpium citri reticulatae viride, 135g of safflower, 110g of eucommia ulmoides, 100g of pseudo-ginseng and 70g of rhizoma curculiginis, and uniformly mixing to obtain mixed powder, wherein the total weight is 1138 g.
Adding the mixed powder into a pan, adding 3414g oleum Sesami, stirring, heating for 30min, stirring, adding 569g vaseline paste, heating, and stirring for 20min to obtain ointment.
Filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
Example 2
Weighing 110g of achyranthes bidentata, 76g of rhizoma cyperi, 108g of scutellaria baicalensis, 80g of ligusticum wallichii, 95g of angelica sinensis, 140g of leonurus, 100g of agastache rugosus, 60g of pericarpium citri reticulatae viride, 135g of safflower, 110g of eucommia ulmoides, 118g of pseudo-ginseng and 75g of rhizoma curculiginis, and uniformly mixing to obtain mixed medicinal powder, wherein the total weight is 1207 g.
Adding the mixed powder into a boiling pot containing 3621g of oleum Sesami, stirring, heating for 30min, stirring, adding 603.5g of vaseline, heating, and stirring for 20min to obtain paste.
Filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
Example 3
Weighing 105g of achyranthes bidentata, 77g of rhizoma cyperi, 105g of scutellaria baicalensis, 80g of ligusticum wallichii, 95g of angelica sinensis, 140g of leonurus, 100g of agastache rugosus, 60g of pericarpium citri reticulatae viride, 135g of safflower, 110g of eucommia ulmoides, 120g of pseudo-ginseng and 70g of rhizoma curculiginis, and uniformly mixing to obtain mixed powder, wherein the total weight is 1197 g.
Adding the mixed powder into a boiling pot containing 3591g of oleum Sesami, stirring, heating for 30min, stirring, adding 598.5g of vaseline, heating, and stirring for 20min to obtain ointment.
Filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
Example 4
Weighing 105g of achyranthes bidentata, 75g of rhizoma cyperi, 105g of scutellaria baicalensis, 85g of ligusticum wallichii, 100g of angelica sinensis, 150g of leonurus, 102g of agastache rugosus, 55g of pericarpium citri reticulatae viride, 125g of safflower, 115g of eucommia ulmoides, 115g of pseudo-ginseng and 80g of rhizoma curculiginis, and uniformly mixing to obtain mixed powder, wherein the total weight is 1212 g.
Adding the mixed powder into a boiling pot containing 3636g of oleum Sesami, stirring, heating for 30min while stirring, adding 606g of vaseline, heating, and stirring for 20min to obtain ointment.
Filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
Example 5
Weighing 105g of achyranthes bidentata, 75g of rhizoma cyperi, 100g of scutellaria baicalensis, 80g of ligusticum wallichii, 98g of angelica sinensis, 145g of leonurus, 105g of agastache rugosus, 60g of pericarpium citri reticulatae viride, 130g of safflower, 105g of eucommia ulmoides, 116g of pseudo-ginseng and 79g of rhizoma curculiginis, and uniformly mixing to obtain mixed medicinal powder with the total weight of 1198 g.
Adding the mixed powder into a boiling pot containing 3594g of oleum Sesami, stirring, heating for 30min, stirring, adding 599g of vaseline, heating, and stirring for 20min to obtain ointment.
Filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
The therapeutic effects of the ointments of examples 1-5 were studied and the results were as follows:
human body tests are carried out on the population suffering from postpartum body pain of various patients, and a pre-test scheme is formulated: the application method comprises applying the plaster to pain parts of parturient 1 time per day, and applying one plaster to the central point of each pain part according to the pain at multiple parts. After 24 hours, the original plaster was removed and 1 additional plaster was replaced for 7 days.
The results were shown by human observation of the results of human trial treatments of the plasters of examples 1-5, respectively, as follows:
example 1: 200 test persons have good test effect. 166 patients with joint pain or general aching pain had no symptoms or had significantly reduced symptoms after use. 7 patients with reduced symptoms of arthralgia or general aching pain; the total significant efficiency is 83 percent, and the total effective rate is 86.5 percent.
Example 2: 200 test persons have good test effect. Among them, 174 patients with joint pain or general aching pain or with symptom disappeared or significantly reduced. 11 patients with joint pain or general aching pain with reduced symptoms; the total significant efficiency is 87 percent, and the total effective rate is 92.5 percent.
Example 3: 200 test persons have good test effect. Of these, 179 patients with joint pain or general aching pain or with no or markedly reduced symptoms after use. 9 patients with reduced symptoms of arthralgia or general aching pain; the total significant efficiency is 89.5 percent, and the total effective rate is 94 percent.
Example 4: 200 test persons have good test effect. 181 patients with joint pain or general aching pain or with symptom disappearance or significant symptom relief after use. 12 patients with joint pain or general aching pain with reduced symptoms; the total significant efficiency is 90.5 percent, and the total effective rate is 96.5 percent.
Example 5: 200 test persons have good test effect. 184 patients with joint pain or general aching pain or with symptom disappearance or obvious symptom relief after use. 13 patients with reduced symptoms of arthralgia or general aching pain; the total significant efficiency is 92 percent, and the total effective rate is 98.5 percent.
The external plaster has consistent curative effect, good and specific effect and definite curative effect on patients with different ages and different disease courses, and no adverse reaction is found in the test.
In conclusion, the externally applied ointment can promote the whole body blood circulation of the lying-in woman, promote the circulation of blood and relieve pain, and has obvious effect on people with postpartum body pain
Although the invention has been described herein with reference to illustrative embodiments thereof, it should be understood that numerous other modifications and embodiments can be devised by those skilled in the art that will fall within the spirit and scope of the principles of this disclosure. More specifically, various variations and modifications may be made to the component parts and/or arrangements of the subject combination arrangement within the scope of the disclosure herein. In addition to variations and modifications in the component parts and/or arrangements, other uses will also be apparent to those skilled in the art.
Claims (5)
1. An externally applied ointment for treating postpartum body pain is characterized by being prepared from the following traditional Chinese medicine components and auxiliary materials in parts by weight:
90-120 parts of achyranthes bidentata; 62-80 parts of rhizoma cyperi;
88-118 parts of scutellaria; 75-95 parts of ligusticum wallichii;
88-110 parts of angelica; 120 portions and 160 portions of motherwort;
85-130 parts of agastache rugosus; 47-70 parts of green tangerine orange peel;
90-165 parts of safflower; 80-132 parts of eucommia;
100 portions of notoginseng and 135 portions; 65-85 parts of rhizoma curculiginis;
the twelve traditional Chinese medicine components are calculated according to dry weight;
the auxiliary materials comprise linseed oil and vaseline paste, wherein 2970 parts of linseed oil and 4200 parts of vaseline paste are used as the auxiliary materials, and 495 parts of vaseline paste are used as the auxiliary materials.
2. The externally applied ointment for treating postpartum body pain according to claim 1, which is characterized by being prepared from the following traditional Chinese medicine components and auxiliary materials in parts by weight:
100 portions of achyranthes bidentata; 75-80 parts of rhizoma cyperi;
99-109 parts of scutellaria; 75-90 parts of ligusticum wallichii;
88-110 parts of angelica; 130 portions and 155 portions of motherwort;
85-110 parts of agastache rugosus; 48-70 parts of green tangerine orange peel;
95-160 parts of safflower; 80-130 parts of eucommia;
115 parts of pseudo-ginseng and 125 parts of sand; 70-85 parts of rhizoma curculiginis;
the twelve traditional Chinese medicine components are calculated according to dry weight;
the auxiliary materials are linseed oil and vaseline paste, and the dosage of the linseed oil is three times of the sum of the weights of all the traditional Chinese medicine components by weight; the vaseline paste is used in an amount of half the weight of the total of all the above components except for the sesame oil.
3. The externally applied ointment for treating postpartum body pain according to claim 2, which is characterized by being prepared from the following traditional Chinese medicine components and auxiliary materials in parts by weight:
100 portions and 105 portions of achyranthes bidentata; 75-78 parts of rhizoma cyperi;
99-105 parts of scutellaria baicalensis; 80-85 parts of ligusticum wallichii;
95-100 parts of angelica; 140 portions of motherwort and 150 portions;
100 portions of agastache rugosus and 105 portions of agastache rugosa; 55-60 parts of green tangerine peel;
125 portions of safflower and 135 portions; 100 portions of eucommia bark and 115 portions;
115 parts of pseudo-ginseng and 120 parts of sand; 70-80 parts of rhizoma curculiginis;
the twelve traditional Chinese medicine components are calculated according to dry weight;
the auxiliary materials are linseed oil and vaseline paste, and the dosage of the linseed oil is three times of the sum of the weights of all the traditional Chinese medicine components by weight; the vaseline paste is used in an amount of half the weight of the total of all the above components except for the sesame oil.
4. The method for preparing an external ointment for treating postpartum pain of body according to any one of claims 1 to 3, characterized by comprising the following steps:
(1) cleaning Achyranthis radix, rhizoma Cyperi, Scutellariae radix, rhizoma Ligustici Chuanxiong, radix Angelicae sinensis, herba Leonuri, herba Agastaches, pericarpium Citri Reticulatae viride, Carthami flos, Eucommiae cortex, Notoginseng radix and rhizoma Curculiginis respectively, drying, pulverizing into 200 mesh fine powder of 180 meshes respectively, weighing various medicinal powders, and mixing twelve medicinal powders at a certain proportion to obtain mixed medicinal powder;
(2) adding oleum Sesami into a decocting pan in advance, adding the mixed medicinal powder into the decocting pan, heating, controlling the temperature of the materials at 70-80 deg.C, stirring, heating and stirring for 30min, adding vaseline, heating and stirring for 20min to obtain paste;
(3) spreading the ointment on non-woven fabric, and cutting into ointment tablet.
5. The preparation method of the external plaster for treating postpartum body pain according to claim 4, characterized in that the specific operation of the step (3) is as follows: filling the paste into a device tank of a plaster spreading machine; setting the thickness of the spread paste to be 1.2mm, the length and the width to be 8cm multiplied by 6cm, starting a paste spreading machine, uniformly spreading the paste on non-woven fabrics according to the specification, and cutting the paste into the required plaster pieces according to the specification and the size.
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| CN1303689A (en) * | 2000-01-07 | 2001-07-18 | 徐柏功 | Medicine for curing gynecopathy |
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| CN101417087B (en) * | 2008-11-13 | 2011-08-10 | 王督 | Medicine for treating gynecology postpartum disease and preparation method thereof |
| CN203342192U (en) * | 2013-01-08 | 2013-12-18 | 天津科雷德医疗科技发展有限公司 | Hot moxibustion plaster |
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| CN1303689A (en) * | 2000-01-07 | 2001-07-18 | 徐柏功 | Medicine for curing gynecopathy |
Non-Patent Citations (2)
| Title |
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| 中药熏蒸治疗产后疼痛 230 例;杨秀芬等;《江西中医药》;20070315;第3卷(第291期);文章第37页左栏第1、3段，右栏最后一段 * |
| 活血化瘀法治疗产后病举隅;孙健;《山东中医杂志》;20100405;第29卷(第4期);文章第283页左栏第1-2段，右栏2.5产后身痛 * |
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