CN109846790A - A kind of moisturizing anti-acne comprising cannabidiol, bright color it is spraying and preparation method thereof - Google Patents

Abstract

The present invention provide a kind of moisturizing anti-acne comprising cannabidiol, bright color it is spraying and preparation method thereof, belong to daily chemicals field, it is described to comprise the following components in parts by weight by spraying: 1-10 parts of cannabidiol, 15-20 parts of A Ganshu benevolence extract of thorn, 10-15 parts of Gotu Kola P.E, 5-10 parts of tea extract, hydrolysis 5-10 parts of myrtle extract, 0-0.05 parts of essence, 0-0.2 parts of vitamin E, 0.03-0.05 parts of preservative, 10-20 parts of glycerine, 30-60 parts of deionized water.Compared with prior art, the invention has the benefit that the dedicated fiery sesame slices extract for the cannabidiol being added is cooperateed with thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract and hydrolysis myrtle extract, there is better moisturizing whitening effect for dry skin, obscure, acne and dark sore etc..

Description

A kind of spraying and its preparation of the moisturizing anti-acne comprising cannabidiol, bright color Method

Technical field

The invention belongs to daily chemicals fields, and in particular to a kind of moisturizing anti-acne comprising cannabidiol, bright color are sprayed And preparation method thereof.

Background technique

Hemp (Cannabis sativa Linn.) is a kind of this raw early plant of the year with important medical value, is belonged to Magnoliatae (Magnoliopsida) Urticales (Urticales) Cannabaceae (Cannabinaceae) Cannabis (Cannabis), Also known as name fiber crops, Chinese fiber crops, fire fiber crops, mountain silk fiber crops, jute and industrial hemp.Physiological activity rich in hemp floral leaf to be bloomed Ingredient includes cannabinoid and non-cannabinoid, and wherein cannabinoid quantity and physiologically active ingredient are more. The cannboid (cannabinoids, CBs) isolated from hemp at present is more than 80 kinds existing, mainly includes cannabidiol (cannabidiol, CBD), tetrahydro hemp (tetrahydrocannabinol, THC), cannabinol (cannabinol, CBN) and Cannabigerol (cannabichromene, CBC) etc., wherein cannabidiol (CBD) and tetrahydrocannabinol (THC) content highest are The Typical Representative of Cannabinoids compound.Studies have shown that there is tetrahydrocannabinol (THC) habituation to cause unreal property, therefore it is medicinal The application in field is greatly limited with development.Cannabidiol (CBD) is different from tetrahydrocannabinol (THC), is not only strong It resists oxidant strenuously, and is the non-habituation active constituent without neurotoxicity, it can antagonism THC excitement cannboid I receptor (CB1R) psychotropic activity caused.In addition to this, Recent study is found, cannabidiol (CBD) has tranquilizing soporific, treatment A series of physiological functions such as epilepsy, neuroprotection, oncotherapy are a kind of natural work in the great application prospect of medicine and other fields Property ingredient.

In recent years, industrial hemp floral leaf extract is used to the preparation of skin care item as effective component or additive In, since it has analgesic, anti-inflammatory, Eradicates spot, Huang of dispelling, anti-acne, anti-ageing and crease-resistant etc. multiple efficacies, skin care item are covered rapidly and are disappeared Take market, especially European skin care item market.The existing skin care item to whitenings moisturizings such as anti-acne, Huangs of dispelling rest essentially within Temporary or surface layer is repaired, and fails fundamentally to solve skin problem.However the Cannadors such as cannabidiol (CBD) are from big A kind of substance of the nontoxic high added value that can be used for the multiple fields such as drug, cosmetics, health food extracted in fried dough twist leaf. The Cannadors such as cannabidiol are the non-additive ingredients in hemp, and THC can be hindered to influence nerve system of human body, not only had There are the pharmacological activity such as anti-spasm, resisting rheumatoid arthritis, antianxiety, also there is the report in terms of skin care.At present in public information There are some reports applied in skin care item industry about industrial hemp extract.For example, CN107982080A discloses hemp Diphenol or Cannador are preparing the purposes in whitening product, demonstrate cannabidiol or Cannador can be effectively Inhibit the activity of tyrosinase, there are good skin whitening effects.But specific preparation method is not provided.CN107811904A A kind of anti-inflammatory nti-freckle toilet cream and preparation method thereof is disclosed, anti-inflammatory nti-freckle toilet cream joined enrichment bisabolol and hemp The dedicated fiery sesame slices extract of diphenol, has apparent anti-inflammatory and Eradicates spot and other effects, wherein retaining the bisabolol collaboration of enrichment The anti-inflammatory and Eradicates spot effectiveness for strengthening cannabidiol can maintain fiery sesame slices extract to play in longer time stronger anti-inflammatory Eradicates spot and other effects.CN107308440A discloses one kind and dispels striae of pregnancy, scar reparation, anti-wrinkle Skin whitening care cosmetics, including monarch drug in a prescription, Ministerial drug, adjutant and make medicine, the monarch drug in a prescription includes oligopeptides and cannabidiol, and the ministerial drug includes carboxylic aminoglucan sodium and hyalomitome Sour sodium, the adjutant include that olive essential oil, vitamin E, almond extracting solution, dandelion extracting solution, Purslane extract, Rhizoma Atractylodis Macrocephalae mention Liquid, Radix Notoginseng freeze-dried powder, Poria cocos extracting solution, bletilla striata extract and adlay extracting solution are taken, it is described that medicine is made to include licorice extract and go Ionized water.By the existing all kinds of skin care item about cannabidiol of comparative study, find existing containing industrial hemp extraction The skin-protection product of object is concentrated mainly in the preparation of white-skinned face function product, and the anti-inflammatory anti-acne and moisturizing for having ignored cannabidiol are dispelled Huang Effect.

Summary of the invention

Technical assignment of the invention is to solve the deficiencies in the prior art, provide a kind of moisturizing anti-acne comprising cannabidiol, Bright color it is spraying and preparation method thereof.The technical scheme is that realize in the following manner, it is specific as follows:

A kind of moisturizing anti-acne comprising cannabidiol, bright color are sprayed, and are comprised the following components in parts by weight: hemp two 1-10 parts of phenol, 15-20 parts of A Ganshu (ARGANIA SPINOSA) benevolence extract of thorn, centella (CENTELLA ASIATICA) mention 10-15 parts of object, 5-10 parts of tea (CAMELLIA SINENSIS) leaf extract, hydrolysis myrtle (MYRTUS COMMUNIS) is taken to mention Take 5-10 parts of object, 0-0.05 parts of essence, 0-0.2 parts of vitamin E, 0.03-0.05 parts of preservative, 10-20 parts of glycerine and go from Sub- water 30-60 parts.

A kind of moisturizing anti-acne comprising cannabidiol, the spraying preparation method of bright color, specifically include following Step:

Step 1: prepare cannabidiol powder, thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract and Hydrolyze myrtle extract:

(1) preparation of cannabidiol: grinding after the floral leaf of hemp plant is dried, the coarse powder of crushing and The alcohol solvent (the W/V solid-liquid ratio of coarse powder and solvent is 1:4, and temperature is controlled at 40~50 DEG C) of 95%w/w is in counter-current extraction tank It is both middle to carry out counter-current extraction in opposite directions, make solvent that the effective component in coarse powder is leached extracting solution out；By extracting solution ((65-75 DEG C) vapors away ethyl alcohol extra in extracting solution to heating under reduced pressure, obtains the concentrate of cannabidiol；In cannabidiol After pure water dilution (solid content of dilution is about 1%-2%) is added in concentrate, gradient elution is carried out using chromatographic column, is received Collect target eluent；Merge target eluent, is concentrated under reduced pressure in 50-70 DEG C, obtains the secondary concentration liquid of cannabidiol；In hemp The alcohol saturated solution of 90%w/w is added in the secondary concentration liquid of diphenol, forms supersaturated solution and is recrystallized, crystallized Cannabidiol is obtained after being dried after object with pure water.Cannabinol purity is not less than 95%.

(2) pierce the preparation of A Ganshu benevolence extract: thorn A Ganshu benevolence is after drying, crushing with means of supercritical extraction or with having Solvent is extracted, and thorn A Ganshu (ARGANIA SPINOSA) benevolence extract is obtained.The purity of the dry tree benevolence extract of Ci A is not less than 90%.

(3) preparation of Gotu Kola P.E: centella (CENTELLA ASIATICA) is faced after drying, crushing with super It extracts or is extracted to obtain centella (CENTELLA ASIATICA) extract with organic solvent in boundary.Gotu Kola P.E uses (20-100): 1 ratio extract.

(4) preparation of tea extract: tea (CAMELLIASINENSIS) leaf uses means of supercritical extraction after drying, crushing Or it is extracted to obtain tea (CAMELLIA SINENSIS) leaf extract with organic solvent.Tea extract purity is not less than 95%.

(5) hydrolyze the preparation of myrtle extract: hydrolysis myrtle (MYRTUS COMMUNIS) is after drying, crushing It is extracted with means of supercritical extraction or with organic solvent to obtain hydrolysis myrtle (MYRTUS COMMUNIS) extract.Hydrolyze myrtle Extract purity is not less than 90%.

Cannabidiol powder, thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract and hydrolysis made above The step of myrtle extract, in no particular order, prepares.

Step 2: according to following parts by weight: 1-10 parts of cannabidiol, thorn 15-20 parts of A Ganshu benevolence extract, centella 10-15 parts of extract, 5-10 parts of tea extract, hydrolysis 5-10 parts of myrtle extract, 0-0.05 parts of essence, vitamin E 0- 0.2 part, 0.03-0.05 parts of preservative, 10-20 parts of glycerine, 30-60 parts of deionized water；Cannabidiol, thorn A Ganshu benevolence are mentioned It is heated after taking object, Gotu Kola P.E, tea extract, hydrolysis myrtle extract, essence, vitamin and preservative to mix molten Glycerine described in Xie Yu, heating temperature are 41-50 DEG C, dissolve into mixed solution and stir evenly, are cooled to after mixing evenly Room temperature (20-25 DEG C) stands 12-24 hours at room temperature；

Step 3: the processing and assembly of container, valve system: the vial of clean drying is preheating to 120-130 DEG C, is taken advantage of Hot dipping enters to make in slush moulding liquid bottleneck or less to adhere to one layer of slush moulding liquid, is upside down in 150-170 DEG C of drying 15min, spare；By valve Various parts are handled respectively, as plastics, nylon and rubber product can in ethyl alcohol (analysis pure) immersion, be dried for standby, stainless steel Spring boils half an hour in 1%-3% lye (lye weight concentration does not require), and distilled water flushing is to without greasy, in ethyl alcohol It impregnates, be dried for standby in (analysis is pure)；By above-mentioned processed part, by the Standard of valve.

Step 4: it the preparing and packaging of mixed liquor: is added in an aseptic environment into mixed solution according to 30-60 parts of parts by weight Continue to stir after deionized water, stir evenly and be cooled to room temperature, filter, abandon filter residue, completes packing.

Step 5: finished product is made in filling propellant: the filling of propellant uses pressure filling.By the mixed liquor prepared in room temperature Under pour into container, installation valve simultaneously tighten.The air in container is first pumped, it then will quantitative propellant by pressure filling machine It is pressed into container, completes finished product preparation.

The invention has the following advantages that

Compared with prior art, the dedicated fiery sesame slices extract and thorn A Ganshu for the cannabidiol that the present invention is added (ARGANIA SPINOSA) benevolence extract, centella (CENTELLA ASIATICA) extract, tea (CAMELLIA SINENSIS) leaf extract and hydrolysis myrtle (MYRTUS COMMUNIS) extract collaboration, for dry skin, obscure, powder Thorn and dark sore etc. have better moisturizing whitening effect.

Specific embodiment

In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention, Technical solution of the present invention is clearly and completely described, it is clear that described embodiment is that a part of the invention is implemented Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creativeness Every other embodiment obtained, shall fall within the protection scope of the present invention under the premise of labour.

Embodiment 1:

The moisturizing anti-acne comprising cannabidiol that the present embodiment provides a kind of, the spraying preparation method of bright color, specifically Including the following steps:

Step 1: in the present embodiment as a raw material for production using the floral leaf of industrial hemp kind " cloud fiber crops No. 1 ", will in It after the floral leaf part of the cannabis plants of flowering period is screened, is laid in baking oven and is dried, temperature is 120 DEG C, the time It is 2 hours, until the water content of hemp floral leaf is less than 6%, is then added into grind in pulverizer to granular size and is 20 mesh；The coarse powder of crushing and the alcohol solvent of 95%w/w (the W/V solid-liquid ratio of coarse powder and solvent is 1:4, and temperature is controlled at 50 DEG C) Counter-current extraction is carried out in opposite directions both in counter-current extraction tank, is leached solvent by the effective component in coarse powder and is extracted out Liquid；By extracting solution heating under reduced pressure (65 DEG C), ethyl alcohol extra in extracting solution is vapored away, the concentrate of cannabidiol is obtained；Big After pure water dilution (solid content of dilution is about 1%-2%) is added in the concentrate of numb diphenol, ladder is carried out using chromatographic column Degree elution, collects target eluent；Merge target eluent, is concentrated under reduced pressure in 70 DEG C, obtains the secondary concentration liquid of cannabidiol； The ethyl alcohol of 90%w/w is added in the secondary concentration liquid of cannabidiol, forms supersaturated solution and is recrystallized, obtain crystal Cannabidiol is obtained after being dried afterwards with pure water.The thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract with And hydrolysis myrtle extract uses existing extraction raw material.

Step 2: according to following parts by weight: 5 parts of cannabidiol, thorn 20 parts of A Ganshu benevolence extract, Gotu Kola P.E 10 parts, 10 parts of tea extract, hydrolysis 5 parts of myrtle extract, 0.05 part of essence, 0.2 part of vitamin E, 0.03 part of preservative, 15 parts of glycerine, 50 parts of deionized water；By cannabidiol, thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract, It dissolves by heating after hydrolyzing myrtle extract, essence, vitamin and preservative mixing in the glycerine, heating temperature 50 DEG C, it dissolves into mixed solution and stirs evenly, be cooled to room temperature (25 DEG C) after mixing evenly, stand 24 hours at room temperature.

Step 3: being preheating to 120 DEG C for the vial of clean drying, and immerse in slush moulding liquid makes bottleneck or less adhere to one while hot Layer slush moulding liquid is upside down in 150 DEG C of drying 15min, spare；The various parts of valve are handled respectively, such as plastics, nylon and rubber Product can be impregnated in ethanol, is dried for standby, and stainless steel spring boils half an hour in 1%-3% lye, and distilled water flushing is extremely Without greasy, impregnate, is dried for standby in ethanol；By above-mentioned processed part, by the Standard of valve.

Step 4: in an aseptic environment into mixed solution according to continuing to stir after 50 parts of addition deionized waters of parts by weight, It stirs evenly and is cooled to room temperature, filter, abandon filter residue, complete packing.

Step 5: being poured into the mixed liquor prepared in container using pressure filling at room temperature, is installed valve and is tightened.First take out The air in container is removed, quantitative propellant is then pressed by container by pressure filling machine, completes the preparation of finished product.

Embodiment 2:

The moisturizing anti-acne comprising cannabidiol that the present embodiment provides a kind of, the spraying preparation method of bright color, specifically Including the following steps:

Step 1: in the present embodiment as a raw material for production using the floral leaf of industrial hemp kind " cloud fiber crops No. 1 ", will in It after the floral leaf part of the cannabis plants of flowering period is screened, is laid in baking oven and is dried, temperature is 130 DEG C, the time It is 3 hours, until the water content of hemp floral leaf is less than 6%, is then added into grind in pulverizer to granular size and is 20 mesh；The coarse powder of crushing and the alcohol solvent of 95%w/w (the W/V solid-liquid ratio of coarse powder and solvent is 1:4, and temperature is controlled at 50 DEG C) Counter-current extraction is carried out in opposite directions both in counter-current extraction tank, is leached solvent by the effective component in coarse powder and is extracted out Liquid；By extracting solution heating under reduced pressure (75 DEG C), ethyl alcohol extra in extracting solution is vapored away, the concentrate of cannabidiol is obtained；Big After pure water dilution (solid content of dilution is about 1%-2%) is added in the concentrate of numb diphenol, ladder is carried out using chromatographic column Degree elution, collects target eluent；Merge target eluent, is concentrated under reduced pressure in 70 DEG C, obtains the secondary concentration liquid of cannabidiol； The ethyl alcohol of 90%w/w is added in the secondary concentration liquid of cannabidiol, forms supersaturated solution and is recrystallized, obtain crystal Cannabidiol is obtained after being dried afterwards with pure water.The thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract with And hydrolysis myrtle extract uses existing extraction raw material.

Step 2: according to following parts by weight: 5 parts of cannabidiol, thorn 20 parts of A Ganshu benevolence extract, Gotu Kola P.E 15 parts, 5 parts of tea extract, hydrolysis 10 parts of myrtle extract, 0.05 part of essence, 0.2 part of vitamin E, 0.05 part of preservative, 20 parts of glycerine, 60 parts of deionized water；By cannabidiol, thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract, It dissolves by heating after hydrolyzing myrtle extract, essence, vitamin and preservative mixing in the glycerine, heating temperature 50 DEG C, it dissolves into mixed solution and stirs evenly, be cooled to room temperature (20 DEG C) after mixing evenly, stand 24 hours at room temperature.

Step 3: being preheating to 130 DEG C for the vial of clean drying, and immerse in slush moulding liquid makes bottleneck or less adhere to one while hot Layer slush moulding liquid is upside down in 170 DEG C of drying 15min, spare；The various parts of valve are handled respectively, such as plastics, nylon and rubber Product can be impregnated in ethanol, is dried for standby, and stainless steel spring boils half an hour in 1%-3% lye, and distilled water flushing is extremely Without greasy, impregnate, is dried for standby in ethanol；By above-mentioned processed part, by the Standard of valve.

Step 4: in an aseptic environment into mixed solution according to continuing to stir after 60 parts of addition deionized waters of parts by weight, It stirs evenly and is cooled to room temperature, filter, abandon filter residue, complete packing.

Step 5: being poured into the mixed liquor prepared in container using pressure filling at room temperature, is installed valve and is tightened.First take out The air in container is removed, quantitative propellant is then pressed by container by pressure filling machine, completes the preparation of finished product.

Embodiment 3:

The moisturizing anti-acne comprising cannabidiol that the present embodiment provides a kind of, the spraying preparation method of bright color, specifically Including the following steps:

Step 1: in the present embodiment as a raw material for production using the floral leaf of industrial hemp kind " cloud fiber crops No. 1 ", will in It after the floral leaf part of the cannabis plants of flowering period is screened, is laid in baking oven and is dried, temperature is 130 DEG C, the time It is 2 hours, until the water content of hemp floral leaf is less than 6%, is then added into grind in pulverizer to granular size and is 20 mesh；The coarse powder of crushing and the alcohol solvent of 95%w/w (the W/V solid-liquid ratio of coarse powder and solvent is 1:4, and temperature is controlled at 50 DEG C) Counter-current extraction is carried out in opposite directions both in counter-current extraction tank, is leached solvent by the effective component in coarse powder and is extracted out Liquid；By extracting solution heating under reduced pressure (75 DEG C), ethyl alcohol extra in extracting solution is vapored away, the concentrate of cannabidiol is obtained；Big After pure water dilution (solid content of dilution is about 1%-2%) is added in the concentrate of numb diphenol, ladder is carried out using chromatographic column Degree elution, collects target eluent；Merge target eluent, is concentrated under reduced pressure in 70 DEG C, obtains the secondary concentration liquid of cannabidiol； The ethyl alcohol of 90%w/w is added in the secondary concentration liquid of cannabidiol, forms supersaturated solution and is recrystallized, obtain crystal Cannabidiol is obtained after being dried afterwards with pure water.The thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract with And hydrolysis myrtle extract uses existing extraction raw material.

Step 2: according to following parts by weight: 10 parts of cannabidiol, 15 parts of A Ganshu benevolence extract of thorn, centella are extracted 15 parts of object, 10 parts of tea extract, hydrolysis 5 parts of myrtle extract, 0.05 part of essence, 0.2 part of vitamin E, preservative 0.03 Part, 15 parts of glycerine, 55 parts of deionized water；Cannabidiol, thorn A Ganshu benevolence extract, Gotu Kola P.E, tealeaves are extracted It dissolves by heating after object, hydrolysis myrtle extract, essence, vitamin and preservative mixing in the glycerine, heating temperature is It 45 DEG C, dissolves into mixed solution and stirs evenly, be cooled to room temperature (25 DEG C) after mixing evenly, it is small to stand 24 at room temperature When.

Step 3: being preheating to 130 DEG C for the vial of clean drying, and immerse in slush moulding liquid makes bottleneck or less adhere to one while hot Layer slush moulding liquid is upside down in 170 DEG C of drying 15min, spare；The various parts of valve are handled respectively, such as plastics, nylon and rubber Product can be impregnated in ethanol, is dried for standby, and stainless steel spring boils half an hour in 1%-3% lye, and distilled water flushing is extremely Without greasy, impregnate, is dried for standby in ethanol；By above-mentioned processed part, by the Standard of valve.

Step 4: in an aseptic environment into mixed solution according to continuing to stir after 55 parts of addition deionized waters of parts by weight, It stirs evenly and is cooled to room temperature, filter, abandon filter residue, complete packing.

Step 5: being poured into the mixed liquor prepared in container using pressure filling at room temperature, is installed valve and is tightened.First take out The air in container is removed, quantitative propellant is then pressed by container by pressure filling machine, completes the preparation of finished product.

Embodiment 4

The difference of the present embodiment and embodiment 3 is only that in step 2 that the content of essence and vitamin is 0 parts by weight, is not added Flavoring essence and vitamin, other are all same as Example 3.

Embodiment 5

The difference of the present embodiment and embodiment 3 is only that in step 4 into mixed solution goes according to 30 parts of additions of parts by weight Ionized water, other are all same as Example 3.

Embodiment 6

The difference of the present embodiment and embodiment 3 is only that the content of glycerine in step 2 is 10 parts by weight, other wholes It is same as Example 3.

Embodiment 7

The difference of the present embodiment and embodiment 3 is only that the content of cannabidiol in step 2 is 1 parts by weight, other wholes It is same as Example 3.

These are only the preferred embodiment of the present invention, is not intended to restrict the invention, for those skilled in the art For member, the invention may be variously modified and varied.All within the spirits and principles of the present invention, it is made it is any modification, Equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (8)

1. a kind of moisturizing anti-acne comprising cannabidiol, bright color are sprayed, it is characterised in that: including each of following parts by weight Component: 1-10 parts of cannabidiol, thorn 15-20 parts of A Ganshu benevolence extract, 10-15 parts of Gotu Kola P.E, tea extract 5- 10 parts, hydrolysis 5-10 parts of myrtle extract, 0-0.05 parts of essence, 0-0.2 parts of vitamin E, 0.03-0.05 parts of preservative, third 10-20 parts of triol, 30-60 parts of deionized water.

2. a kind of moisturizing anti-acne comprising cannabidiol, the spraying preparation method of bright color, which is characterized in that including following Several steps:

Step 1: extraction prepares cannabidiol, prepare thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract and Hydrolyze myrtle extract:

Step 2: it the preparation of mixed liquor: requires to mention cannabidiol, thorn A Ganshu benevolence extract, centella according to parts by weight It dissolves by heating after taking object, tea extract, hydrolysis myrtle extract, essence, vitamin and preservative mixing in described the third three Alcohol dissolves into mixed solution and stirs evenly, is cooled to and is stored at room temperature；

Step 3: finished product is made: according to continuing after 30-60 parts of addition ionized waters of parts by weight in the mixed solution formed to step 2 Stirring, stirs evenly and is cooled to room temperature, filters, and abandons filter residue, filtrate is made spraying.

3. the moisturizing anti-acne according to claim 2 comprising cannabidiol, the spraying preparation method of bright color, special Sign is, further comprising the steps of between the step 2 and three:

The processing and assembly of container, valve system: the vial of clean drying is preheating to 120-130 DEG C, immerses slush moulding while hot So that bottleneck or less is adhered to one layer of slush moulding liquid in liquid, is upside down in 150-170 DEG C of drying 15min, it is spare；By the various parts of valve point Other places reason, wherein plastics, nylon and rubber product are impregnated in ethanol, are dried for standby, and stainless steel spring is in 1%-3% lye It boils half an hour, distilled water flushing is impregnated in ethanol, is dried for standby to without greasy；By above-mentioned processed part, by valve Standard.

4. the moisturizing anti-acne according to claim 2 comprising cannabidiol, the spraying preparation method of bright color, special Sign is that the filtrate is made spraying especially by following steps:

Finished product is made in filling propellant:

The filling of propellant uses pressure filling, and the mixed liquor prepared is poured into container at room temperature, installs valve and tightens, first The air in container is pumped, quantitative propellant is then pressed by container by pressure filling machine, completes spraying finished product preparation.

5. the moisturizing anti-acne according to claim 2 comprising cannabidiol, the spraying preparation method of bright color, special Sign is, the preparation of the cannabidiol specifically: grinds, crushes after the floral leaf of hemp plant is dried Coarse powder and the alcohol solvent of 95%w/w carry out counter-current extraction in opposite directions both in counter-current extraction tank, wherein coarse powder W/V solid-liquid ratio with solvent is 1:4, and temperature controls at 40-50 DEG C, leaches solvent by the effective component in coarse powder and extract out Liquid；By extracting solution heating under reduced pressure, heating temperature is 65-75 DEG C, vapors away ethyl alcohol extra in extracting solution, obtains cannabidiol Concentrate；Pure water dilution is added in the concentrate of cannabidiol, the solid content of dilution is about 1%-2%, using chromatography Column carries out gradient elution, collects target eluent；Merge target eluent, is concentrated under reduced pressure in 50-70 DEG C, obtains cannabidiol Secondary concentration liquid；The ethyl alcohol of 90%w/w is added in the secondary concentration liquid of cannabidiol, forms supersaturated solution and is recrystallized Afterwards, cannabidiol is obtained after being dried with pure water.

6. the moisturizing anti-acne according to claim 2 comprising cannabidiol, the spraying preparation method of bright color, special Sign is that the cannabinol purity is not less than 95%；The purity of the thorn A Ganshu benevolence extract is not less than 90%；The accumulated snow Careless extract uses (20-100): 1 ratio extract；The tea extract purity is not less than 95%；The fragrant peach of the hydrolysis The wooden extract purity is not less than 90%.

7. the moisturizing anti-acne according to claim 2 comprising cannabidiol, bright color is spraying and preparation method thereof, It is characterized in that, by cannabidiol, thorn A Ganshu benevolence extract, Gotu Kola P.E, tea extract, hydrolysis in the step 2 It being dissolved by heating after myrtle extract, essence, vitamin and preservative mixing in the glycerine, heating temperature is 41-50 DEG C, It dissolves into mixed solution and stirs evenly, be cooled to room temperature after mixing evenly, stand 12-24 hours at room temperature.

8. being sprayed according to claim 2 comprising the moisturizing anti-acne of cannabidiol, bright color, it is characterised in that: described The kind of hemp plant be selected as " cloud fiber crops No. 1 ".