CN109827904A - A kind of reaction pool device based on micro-cantilever beam sensor - Google Patents

A kind of reaction pool device based on micro-cantilever beam sensor Download PDF

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Publication number
CN109827904A
CN109827904A CN201910206668.4A CN201910206668A CN109827904A CN 109827904 A CN109827904 A CN 109827904A CN 201910206668 A CN201910206668 A CN 201910206668A CN 109827904 A CN109827904 A CN 109827904A
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China
Prior art keywords
micro
cantilever
reaction tank
matrix
clamping device
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Pending
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CN201910206668.4A
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Chinese (zh)
Inventor
梅永松
薛长国
滕艳华
张飞
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Anhui University of Science and Technology
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Anhui University of Science and Technology
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Priority to CN201910206668.4A priority Critical patent/CN109827904A/en
Publication of CN109827904A publication Critical patent/CN109827904A/en
Pending legal-status Critical Current

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Abstract

The present invention relates to a kind of reaction pool device based on micro-cantilever beam sensor, including micro-cantilever clamping device, reaction tank matrix, rubber ring, transparent glass sheet, metal cover board and solution inlet and outlet;The micro-cantilever clamping device is made of the preferable spring of tensile property, inserted metal bar and clamping matrix;Reaction tank matrix left and right ends be solution or inlet and outlet, median slot place micro-cantilever clamping device;Reaction tank upper grooves periphery is entangled rubber ring along with transparent glass sheet and then is fixed with a metal cover board and screw, and closed environment is created;Structure of the invention principle is simple, it is easy to operate and clamp micro-cantilever stablize.

Description

A kind of reaction pool device based on micro-cantilever beam sensor
Technical field
The present invention relates to a kind of design of reaction pool device, specially a kind of reaction pool devices based on micro-cantilever.
Background technique
Micro-cantilever is one of simplest MEMS device, and constructs the basic unit of other complicated MEMS device.Its Size is very small, has many advantages, such as that high sensitivity, effect are strong.Micro-cantilever beam sensor can be used for detecting macromolecular, such as Detect the concentration of antigen-antibody in the speed and body fluid of Polymer adsorption.It is closed so to design one kind, it is simply, anti-for liquid The container answered then becomes a committed step.Existing reaction tank container joint is excessively complicated in the world at present and is mostly quartz It is made Deng material costly.Therefore, it is necessary to design a kind of simple, reliable and cheap reaction pool device, this hair Bright place in order to avoid the shortcomings of the prior art, provides a kind of reaction pool device based on micro-cantilever beam sensor, In the device, micro-cantilever clamping device and reaction tank matrix are separate type, avoid and are placing micro- hang because reaction pool size is small Existing trouble when arm beam.By rubber ring, transparent glass sheet and metal cover board create the environment being completely closed.
In document " micro-cantilever biochemical sensor development and detection application ", the micro-cantilever reaction tank that author proposes is pressed from both sides It holds and is structure as a whole with reaction tank matrix, place micro-cantilever operating difficulties, be easy to damage and airtightness is poor.
In document " Influence of Fluid Cell Design on the Frequency Response of AFM Microcantilevers in Liquid Media " in, the reaction tank of author designed is made of quartz, and price is extremely Valuableness, and it is exposed in external environment to be retained as a thin wire, easily snaps off.
Summary of the invention
The present invention in order to avoid the shortcomings of the prior art place, provide it is a kind of based on micro-cantilever reaction tank dress It sets, in the apparatus, micro-cantilever clamping device and reaction tank matrix are separate type, are avoided because pool size is small is placing for reaction Existing trouble when micro-cantilever.By rubber ring, transparent glass sheet and metal cover board create the environment being completely closed.
This solution technical problem adopts the following technical scheme that
One detachable micro-cantilever clamping device is made of spring, inserted metal loop bar and clamping matrix;
One reaction tank matrix, the matrix are made of the stainless steel of a rectangular block shape, and reaction tank internal structure is by solution groove It is formed with micro-cantilever clamp groove, there is the groove of a placement rubber ring and metal cover board, table on reaction tank above solution groove There are four screw holes in face, are finally fixed up with a metal cover board and screw, constitute closed environment.
The micro-cantilever clamping device usage mode is to be pulled outward to stretch end with a hand, so that press beam end is the same as micro- outstanding Then the separation of arm beam notch places micro-cantilever with another hand and finally unclamps hand, micro-cantilever is just clamped by stable.
It is recessed that the solution groove horizontal plane outline of the reaction tank intrinsic silicon is higher than the micro-cantilever clamping come round therewith Slot avoids shaking reaction tank that clamping device is fallen off, and micro-cantilever clamp groove height is higher than micro-cantilever clamping dress Set, make micro-cantilever clamping device completely into reaction tank inside, reaction tank matrix or so respectively the entrance comprising a solution and One outlet.
Compared with the prior art, the invention has the advantages that:
1. micro-cantilever clamping device of the present invention is detachable disconnected from each other with reaction tank matrix, so that micro- outstanding placing The fault that arm beam avoids manual operation causes the damage of micro-cantilever;
2. the present invention is integrated with stainless steel metal and is made, at low cost, can come into operation extensively;
3. the present invention is created for the detection of liquids and gases by rubber ring, transparent glass sheet and metal plate and is completely closed Environment so that the disengaging of liquid it is unobstructed smoothly.
Detailed description of the invention
Fig. 1 is micro-cantilever clamping device schematic diagram
Fig. 2 is micro-cantilever clamping device matrix schematic diagram
Fig. 3 is that the insertion of micro-cantilever clamping device is metallic rod schematic diagram
Fig. 4 is micro-cantilever clamping principle enlarged drawing
Fig. 5 is a kind of reaction tank schematic device based on micro-cantilever beam sensor of the present invention
Fig. 6 is reaction tank matrix schematic diagram
Fig. 7 is metal cover board schematic diagram
Figure label: 1 micro-cantilever notch, 2 springs, 3 stretch end, 4 clamping matrixes, 5 metal club heads, 6 springs and metal Bar groove, 7 micro-cantilevers, 8 spring loop bars, 9 press beam ends, 10 screws, 11 metal cover boards, 12 micro-cantilever clamping devices, 13 are instead Answer Chi Jiti, 14 imports, 15 transparent glass sheets, 16 outlets, 17 screw holes, 18 rubber rings and transparent glass film trap.
Specific embodiment
The invention patent is described in detail referring to Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6 and Fig. 7, so as to technical staff Understand.
Embodiment 1
As shown in Figure 1, Figure 2, Figure 3 and Figure 4, a kind of reaction pool device based on micro-cantilever beam sensor includes:
Micro-cantilever clamping device (12) and reaction tank matrix (13) are disconnected from each other, and hand-pulling stretching end (3) makes metal Head (5) is separated with micro-cantilever notch (1), and placing after micro-cantilever (7) unclamp hand makes metal under the action of spring force (2) Head (5) pushes down micro-cantilever (7) with micro-cantilever notch (1).Shown in as shown in Fig. 5, Fig. 6 and Fig. 7,
One reaction tank matrix (13), the reaction tank matrix (13) are rectangle stainless steel material, and micro-cantilever is clamped and is filled Set in (12) intercalation reaction pond matrix (13), first put on rubber ring and transparent glass film trap (18) rubber ring cover again it is transparent Sheet glass (15) is finally fixed with four screws (10) and metal cover board (11), and creation is entirely capable of closed environment.
Embodiment 2
A kind of reaction pool device based on micro-cantilever beam sensor is using steps are as follows:
Micro-cantilever used in the device chooses German Micro-motive company Octo500c type more popular on the market Number, the micro-cantilever length and width of Octo500c model is 2.5mm;Closed ring is stablized and is created in micro-cantilever clamping Behind border, by liquid or gas from import (14) into out from outlet (16).Upper transparent sheet glass passes through optical test path.
The present invention is illustrated by specific implementation process, without departing from the present invention, can be with Various exchanges and same replacement are carried out to the present invention.Therefore, the present invention is not limited to disclosed specific embodiment, and should The whole embodiments fallen within the scope of the appended claims.

Claims (3)

1. a kind of reaction pool device based on micro-cantilever beam sensor, characterized by comprising:
One detachable micro-cantilever clamping device is made of spring, inserted metal loop bar and clamping matrix;
One reaction tank matrix, the matrix are made of the stainless steel of a rectangular block shape, and reaction tank internal structure is by solution groove and micro- There are the groove of a placement rubber ring and metal cover board in cantilever beam clamp groove composition, solution groove top, and reaction tank upper surface has Four screw holes are finally fixed up with a metal cover board and screw, constitute closed environment.
2. a kind of reaction pool device based on micro-cantilever beam sensor according to claim 1, it is characterised in that: described is micro- Cantilever beam clamping device usage mode is to be pulled outward to stretch end with a hand, so that then press beam end is separated with micro-cantilever notch Micro-cantilever is placed with another hand and finally unclamps hand, and micro-cantilever is just clamped by stable.
3. a kind of reaction pool device based on micro-cantilever beam sensor according to claim 1, it is characterised in that: described is anti- It answers the solution groove horizontal plane outline of pond intrinsic silicon to be higher than the micro-cantilever clamp groove come round therewith, avoids shaking reaction tank So that clamping device falls off, and micro-cantilever clamp groove height is higher than micro-cantilever clamping device, clamps micro-cantilever For device completely into reaction tank inside, reaction tank matrix or so respectively includes the entrance and one outlet of a solution.
CN201910206668.4A 2019-03-19 2019-03-19 A kind of reaction pool device based on micro-cantilever beam sensor Pending CN109827904A (en)

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Publication number Priority date Publication date Assignee Title
CN110231390A (en) * 2019-07-02 2019-09-13 安徽理工大学 In-situ test electrolytic cell and its detection method based on micro-cantilever sensing technology

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Application publication date: 20190531