CN109821112B - Piezoelectric stack driving type liquid medicine injection device - Google Patents
Piezoelectric stack driving type liquid medicine injection device Download PDFInfo
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- CN109821112B CN109821112B CN201910166695.3A CN201910166695A CN109821112B CN 109821112 B CN109821112 B CN 109821112B CN 201910166695 A CN201910166695 A CN 201910166695A CN 109821112 B CN109821112 B CN 109821112B
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Abstract
The invention relates to a piezoelectric stack driving type liquid medicine injection device, and belongs to the field of medical instruments. The main body is provided with an injector, a cylinder cavity and a guide hole, the cylinder cavity is divided into a left cavity and a right cavity by a cylinder cavity piston, and a cylinder cavity piston push rod is abutted against an injector piston push rod; the base is provided with an inlet hole, at least two sinking cavity groups with the quantity of sinking cavities increasing from right to left, an outlet cavity and an air storage chamber; an inlet cavity and an air outlet hole are arranged on the leftmost sinking cavity in each sinking cavity group, air inlet and outlet holes are arranged on the other sinking cavities, and valve plates are arranged in the inlet and outlet cavities; the main body is arranged on the base, a diaphragm is pressed between the main body and the base, the top block is pressed on the diaphragm by the piezoelectric stack in the guide hole, and the sealing ring is pressed in the sunken cavity by the diaphragm to form a compression cavity; compression cavities in the same sinking cavity group are connected in parallel to form a compression cavity group, and the compression cavity groups are connected in series; the left cavity and the right cavity are connected with an air storage chamber through an air delivery pipe and a reversing valve; in operation, the deformation directions of the diaphragms in the same compression cavity group are the same, and the deformation directions of the diaphragms in two adjacent compression cavity groups are opposite.
Description
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to a piezoelectric stack driving type liquid medicine injection device.
Background
The injection administration mainly comprises intravenous injection, intramuscular injection, subcutaneous injection and the like. Intravenous injection is also called infusion administration, and most of the existing infusion devices are composed of an infusion bottle, an infusion tube and an infusion support, wherein the infusion bottle is hung on the infusion support, flows by the self weight of liquid medicine and is injected into a blood vessel of a person through the infusion tube. This infusion mode brings about many problems in practical use: the flow is adjusted by a manual method, and the flow control precision is insufficient; the patient needs to lift the infusion bottle by others when walking or going to the toilet, and the like, so that the movement is inconvenient and the blood can flow back when the height of the infusion bottle is not enough; the patient or the nursing staff is required to watch for a long time, and if the completion of the infusion is not found in time, accidents can be caused; the liquid medicine contacts with air, and the pollution possibility exists when the ambient air is unclean. In addition to the above direct problems, the infusion time is sometimes shortened by reducing the amount of solution, increasing the infusion speed, and the like, which not only burdens the heart, but also affects the therapeutic effect: the most important disadvantage of intramuscular injection and subcutaneous injection, which inject drugs into muscle or subcutaneous tissue in a relatively short time, is that the difference of blood drug concentration is large in one injection period, which is not favorable for effective absorption and utilization of drugs because: most drugs have a better concentration range in human body, and have toxic and side effects when the concentration of the drugs is too high, and have no treatment effect when the concentration of the drugs is too low. Therefore, a miniature portable controlled drug delivery device or system that can prolong the drug injection time and maintain reasonable drug concentration is urgently needed in the medical field.
Disclosure of Invention
In order to improve the gas output pressure, the invention provides a piezoelectric stack driving type liquid medicine injection device, and the embodiment of the invention is as follows: the base is provided with an inlet hole, at least two sinking cavity groups consisting of sinking cavities, an outlet cavity and an air storage chamber, and the number of the sinking cavities contained in each sinking cavity group from right to left is increased in sequence; the bottom wall of the leftmost sinking cavity in each sinking cavity group is provided with an inlet cavity and an outlet hole, and the bottom walls of other sinking cavities are provided with inlet and outlet holes; an inlet cavity in the leftmost sinking cavity group is communicated with the inlet hole, a rightmost air outlet hole in the rightmost sinking cavity group is communicated with the air storage chamber through an outlet cavity, two adjacent air inlet and outlet holes in the rest of the same sinking cavity group are communicated, and adjacent air outlet holes in the left and right adjacent sinking cavity groups are communicated with the inlet cavity; the inlet and outlet cavities and the valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve; the top of the main body is provided with an injector, a baffle plate provided with a cylinder cavity and a sliding chute, the bottom of the main body is provided with a guide hole, the diameters of the guide hole and the sinking cavity are equal, and the central line of the cylinder cavity is positioned in the horizontal plane; a main piston is sleeved in the cylinder cavity, and a cylinder cover is arranged at the end part of the side wall of the cylinder cavity; the main piston divides the cylinder cavity into a left cavity and a right cavity; the injector consists of a medicine cylinder and an auxiliary piston, the auxiliary piston is arranged in the medicine cylinder and forms a medicine cavity with the medicine cylinder, an ear plate at one end of the medicine cylinder is arranged in a chute of the baffle, and a transfusion tube with a needle head is arranged at the other end of the medicine cylinder; the push rod of the main piston extends out of the through hole on the left wall of the cylinder cavity and abuts against the push rod of the auxiliary piston; the main body is arranged on the base through a screw, a diaphragm is pressed between the main body and the base, the guide hole and the sinking cavity are symmetrically arranged on the upper side and the lower side of the diaphragm, the piezoelectric stack in the guide hole presses the top block on the diaphragm, the top block is T-shaped, the small end of the top block is contacted with the diaphragm, and the side wall of the large end of the top block is contacted with the inner wall of the guide hole; the diaphragm presses the sealing ring in the counter bore to form a compression chamber; compression cavities in the same sinking cavity group are connected in parallel to form a compression cavity group, and the compression cavity groups are connected in series; the left cavity and the right cavity are connected with a reversing valve through gas pipes, the reversing valve is connected with a gas storage chamber through the gas pipes, and the reversing valve is a three-position four-way valve; in operation, the deformation directions of the diaphragms in the same compression cavity group are the same, namely the piezoelectric stacks in the guide holes corresponding to the sinking cavities in the same sinking cavity group are extended or shortened, and the deformation directions of the diaphragms in two adjacent compression cavity groups are opposite.
Take the liquid medicine injection device who has three compression chamber group as the example, from right side to left side, the heavy chamber group is defined as heavy chamber group one, two and three in proper order, and the import valve is defined as import valve one, two and three in proper order, and the compression chamber group is defined as compression chamber group one, two and three in proper order, then specific working process is: in the upper half cycle, the volumes of the compression cavity group I and the compression cavity group III are increased, the volume of the compression cavity group II is reduced, the inlet valve I and the inlet valve III are opened, the inlet valve II and the outlet valve are closed, the compression cavity group I and the compression cavity group III suck gas, and the compression cavity group II discharges gas, which is a suction process; in the lower half cycle, the volumes of the first compression cavity group and the third compression cavity group are reduced, the volume of the second compression cavity group is increased, the first inlet valve and the third inlet valve are closed, the second inlet valve and the second outlet valve are opened, the first compression cavity group and the third compression cavity group discharge gas, and the second compression cavity group sucks gas, which is a discharge process; in the suction and discharge processes, the gas undergoes the progressive accumulated compression of the compression cavity groups III, II and I, and the output pressure is high; each compression cavity group performs gradual accumulation compression on the gas and then discharges the gas into the gas storage chamber, and when the valve core of the reversing valve is positioned at the middle position, the gas in the gas storage chamber and the liquid medicine in the medicine cavity are not output; when the valve core of the reversing valve is in the left position, the gas in the gas storage chamber enters the right cavity through the gas transmission pipe and pushes the main piston and the auxiliary piston to move leftwards, and the liquid medicine in the medicine cavity is output through the needle head of the liquid transmission pipe; when the valve core of the reversing valve is arranged at the right position, the gas in the gas storage chamber enters the left cavity through the gas pipe and pushes the main piston to move rightwards, the gas in the right cavity is discharged through the gas pipe and the reversing valve, the main piston is reset, and the injector is replaced.
In the invention, the maximum gas storage pressure of the gas storage chamber is Pmax＝P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, namely the ratio of the volume variation of the compression cavity to the volume of the compression cavity caused by the expansion and contraction deformation of the piezoelectric stack, beta is more than 1 and is the minimum value of the number ratio of the compression cavities contained in each adjacent compression cavity group, and n is more than or equal to 2 and is the number of the compression cavity groups; in order to obtain the maximum compression ratio, the optimal radius ratio of the small end to the large end of the top block is respectively 0.79, 0.65 and 0.55 when the diaphragm is beryllium bronze with the thickness of 0.1, 0.2 and 0.3mm, and the height of the compression cavity is the elongation of the piezoelectric stack under the action of voltage; when two adjacent compression cavity groups are communicated with each other, namely when a valve plate between the two adjacent compression cavity groups is opened, the volume change quantity of the compression cavity group with the larger volume is not less than the volume change quantity of the compression cavity group with the smaller volume.
Advantages and features: the output of the liquid medicine is controlled by the coupling action of the piezoelectric driver and the gas, so that the transfusion speed is easily and accurately controlled by the driving voltage; a hanging device is not needed during intravenous injection, and the intravenous injection device is convenient to move and carry; the liquid medicine is not contacted with the air, the phenomena of liquid medicine pollution, gas entering blood vessels, blood backflow and the like can not occur, real-time watching is not needed, and the device is safe and reliable; when the injection is injected into muscles and subcutaneous tissues, the injection time can be prolonged as required, the problem of uneven blood concentration in a human body caused by manual rapid injection is avoided, and the curative effect of the medicine is improved.
Drawings
FIG. 1 is a sectional view showing the structure and structure of a liquid medicine injector according to a preferred embodiment of the present invention;
FIG. 2 is a cross-sectional view A-A of FIG. 1;
FIG. 3 is a schematic structural view of an upper housing according to a preferred embodiment of the present invention;
FIG. 4 is a left side view of FIG. 3;
FIG. 5 is a schematic view of the structure of the syringe in accordance with a preferred embodiment of the present invention
FIG. 6 is a schematic structural diagram of a base in accordance with a preferred embodiment of the present invention;
FIG. 7 is a top view of FIG. 7;
fig. 8 is a schematic diagram illustrating the relationship between the valve switch and the piezoelectric stack deformation in a preferred embodiment of the invention.
Detailed Description
The base c is provided with an inlet hole c1, at least two sinking cavity groups Ci consisting of sinking cavities c2, an outlet cavity c3 and an air storage chamber c7, and the number of the sinking cavities c2 contained in each sinking cavity group Ci from right to left is increased in sequence; the bottom wall of the leftmost sinking chamber c2 in each sinking chamber group Ci is provided with an inlet chamber c4 and an outlet hole c5, and the bottom walls of the other sinking chambers c2 are provided with an inlet hole c6 and an outlet hole c 5; an inlet cavity c4 in the leftmost sinking cavity group Ci is communicated with an inlet hole c1, a rightmost air outlet hole c5 in the rightmost sinking cavity group Ci is communicated with an air storage chamber c7 through an outlet cavity c3, two adjacent air inlet holes c6 and air outlet holes c5 in the rest same sinking cavity group Ci are communicated, and two adjacent air outlet holes c5 and inlet cavities c4 in the left and right adjacent sinking cavity groups Ci are communicated; the inlet chamber c4 and the outlet chamber c3 and the valve plate f arranged in the inlet chamber c4 and the outlet chamber c3 respectively form an inlet valve vi and an outlet valve v; the top of the main body a is provided with an injector z, a cylinder cavity a3 and a baffle a1 with a chute a2, the bottom of the main body a is provided with a guide hole a7, and the diameters of the guide hole a7 and the sinking cavity c2 are equal; the centerline of cylinder chamber a3 is in the horizontal plane; a main piston h is sleeved in the cylinder cavity a3, and a cylinder cover g is arranged at the end part of the side wall of the cylinder cavity a 3; the main piston h divides the cylinder chamber a3 into a left chamber a5 and a right chamber a 6; the injector z is composed of a medicine cylinder z1 and an auxiliary piston z2, the auxiliary piston z2 is arranged in the medicine cylinder z1 and forms a medicine cavity z3 together with the medicine cylinder z1, an ear plate z4 at one end of the medicine cylinder z1 is arranged in a sliding groove a2 of a baffle a1, and an infusion tube with a needle is arranged at the other end of the medicine cylinder z 4; the push rod of the main piston h extends out of a through hole on the left wall a4 of the cylinder cavity and is abutted against the push rod of the auxiliary piston z 2; the main body a is installed on a base c through a screw, a diaphragm k is pressed between the main body a and the base c, a guide hole a7 and a sinking cavity c2 are symmetrically arranged on the upper side and the lower side of the diaphragm k, a top block b is pressed on the diaphragm k by a piezoelectric stack d in the guide hole a7, the top block b is T-shaped, the small end of the top block b is in contact with the diaphragm k, and the side wall of the large end of the top block is in contact with the inner wall of the guide hole a 7; the diaphragm k presses the sealing ring in the sinking chamber C2 to form a compression chamber C; compression chambers C in the same sinking chamber group Ci are connected in parallel to form a compression chamber group Yi, and the compression chamber groups Yi are connected in series; the left cavity a5 and the right cavity a6 are connected with a reversing valve e through air pipes, the reversing valve e is connected with an air storage chamber c7 through air pipes, and the reversing valve e is a three-position four-way valve; in operation, the deformation directions of the diaphragms k in the same compression chamber group Yi are the same, that is, the piezoelectric stacks d in the guide holes a7 corresponding to the respective sinking chambers C in the same sinking chamber group Ci are all extended or shortened, and the deformation directions of the diaphragms k in two adjacent compression chamber groups Yi are opposite.
In the invention, i in a sinking chamber group Ci, an inlet valve vi and a compression chamber group Yi represents a serial number from right to left, and i is 1, 2 and 3; taking a liquid medicine injection device with three compression cavity groups Yi as an example, from right to left, the sinking cavity group Ci is sequentially defined as sinking cavity groups one C1, two C2 and three C3, the inlet valve vi is sequentially defined as inlet valves one v1, two v2 and three v3, and the compression cavity group Yi is sequentially defined as compression cavity groups one Y1, two Y2 and three Y3, then the specific working process is as follows: in the first half cycle, the volumes of the compression chamber group I Y1 and the compression chamber group II Y3 are increased, the volume of the compression chamber group II Y2 is decreased, the inlet valves I1 and III V3 are opened, the inlet valves II v2 and the outlet valves II v are closed, the compression chamber group I Y1 and III Y3 suck gas, and the compression chamber group II Y2 discharges gas, which is a suction process; in the second half cycle, the volumes of the compression chamber group I Y1 and the compression chamber group II Y3 are reduced, the volume of the compression chamber group II Y2 is increased, the inlet valves I1 and III v3 are closed, the inlet valves II v2 and the outlet valves II v are opened, the compression chamber group I Y1 and III Y3 discharge gas, and the compression chamber group II Y2 sucks gas, which is a discharge process; during the suction and the discharge, the gas undergoes the progressive accumulated compression of the three Y3, two Y2 and one Y1 compression cavity groups, and the output pressure is high; each compression cavity group Yi carries out gradual accumulation and compression on the gas and then discharges the gas into a gas storage chamber c7, and when the valve core of the reversing valve e is positioned at the middle position, the gas in the gas storage chamber c7 and the liquid medicine in the medicine cavity z3 are not output; when the valve core of the reversing valve e is in the left position, the gas in the gas storage chamber c7 enters the right cavity a6 through the gas transmission pipe and pushes the main piston h and the auxiliary piston z2 to move leftwards, and the liquid medicine in the medicine cavity z3 is output through the liquid transmission pipe and the needle head; when the valve core of the reversing valve e is arranged at the right position, the gas in the gas storage chamber c7 enters the left cavity a5 through the gas pipe and pushes the main piston h to move rightwards, the gas in the right cavity a6 is discharged through the gas pipe and the reversing valve e, and the main piston h is reset; the syringe z is replaced.
In the present invention, the maximum gas storage pressure of the gas storage chamber c7 is Pmax＝P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, namely the ratio of the volume change quantity of the compression cavity C caused by the expansion and contraction deformation of the piezoelectric stack d to the volume of the compression cavity C, beta is more than 1 and is the minimum value of the number ratio of the compression cavities C contained in each adjacent compression cavity group Yi, and n is more than or equal to 2 and is the number of the compression cavity groups Yi; in order to obtain the maximum compression ratio, the optimal radius ratio of the small end to the large end of the top block b is respectively 0.79, 0.65 and 0.55 when the diaphragm k is beryllium bronze with the thickness of 0.1, 0.2 and 0.3mm, and the height of a compression cavity is the elongation of the piezoelectric stack d under the action of voltage; when two adjacent compression cavity groups Yi are mutually communicated, namely when a valve plate f between the two adjacent compression cavity groups is opened, the volume change quantity of the compression cavity group Yi with the larger volume is not less than that of the compression cavity group Yi with the smaller volume.
Claims (1)
1. A piezoelectric stack driving type liquid medicine injection device is characterized in that: the base is provided with an inlet hole, at least two sinking cavity groups consisting of sinking cavities, an outlet cavity and an air storage chamber, and the number of the sinking cavities contained in each sinking cavity group from right to left is increased in sequence; the bottom wall of the leftmost sinking cavity in each sinking cavity group is provided with an inlet cavity and an outlet hole, and the bottom walls of other sinking cavities are provided with inlet and outlet holes; the inlet and outlet cavities and the valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve; the top of the main body is provided with an injector, a baffle plate provided with a cylinder cavity and a sliding chute, and the bottom of the main body is provided with a guide hole; a main piston is sleeved in the cylinder cavity, and a cylinder cover is arranged at the end part of the side wall of the cylinder cavity; the main piston divides the cylinder cavity into a left cavity and a right cavity; the injector consists of a medicine cylinder and an auxiliary piston, the auxiliary piston is arranged in the medicine cylinder and forms a medicine cavity with the medicine cylinder, an ear plate at one end of the medicine cylinder is arranged in a chute of the baffle, and a transfusion tube with a needle head is arranged at the other end of the medicine cylinder; the push rod of the main piston extends out of the through hole on the left wall of the cylinder cavity and abuts against the push rod of the auxiliary piston; the main body is arranged on the base, a diaphragm is pressed between the main body and the base, the guide hole and the sinking cavity are symmetrically arranged on the upper side and the lower side of the diaphragm, the top block is pressed on the diaphragm by a piezoelectric stack in the guide hole, the piston is T-shaped, the small end of the piston is contacted with the diaphragm, and the side wall of the large end of the piston is contacted with the inner wall of the guide hole; when the diaphragm is a beryllium bronze film with the thickness of 0.1mm, 0.2mm and 0.3mm, the optimum straightness of the small end and the large end of the pistonThe diameter ratio is respectively 0.79, 0.65 and 0.55; the diaphragm presses the sealing ring in the counter bore to form a compression chamber; compression cavities in the same sinking cavity group are connected in parallel to form a compression cavity group, and the compression cavity groups are connected in series; the left cavity and the right cavity are connected with a reversing valve through gas pipes, and the reversing valve is connected with a gas storage chamber through the gas pipes; the maximum gas storage pressure of the gas storage chamber is Pmax＝P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, beta is more than 1 and is the minimum value of the number ratio of the compression cavities contained in each adjacent compression cavity group, and n is more than or equal to 2 and is the number of the compression cavity groups; in operation, the deformation directions of the diaphragms in the same compression cavity group are the same, and the deformation directions of the diaphragms in two adjacent compression cavity groups are opposite.
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| CN201910166695.3A CN109821112B (en) | 2019-03-01 | 2019-03-01 | Piezoelectric stack driving type liquid medicine injection device |
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| CN201910166695.3A CN109821112B (en) | 2019-03-01 | 2019-03-01 | Piezoelectric stack driving type liquid medicine injection device |
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| CN109821112A CN109821112A (en) | 2019-05-31 |
| CN109821112B true CN109821112B (en) | 2021-03-02 |
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| CN102553754A (en) * | 2012-01-13 | 2012-07-11 | 吉林大学 | Piezoelectric-gas mixture control type fluid jet device |
| US9212861B2 (en) * | 2014-04-25 | 2015-12-15 | David Panak | Feedback-controlled re-targeting apparatus for automatic firearm |
| CN104179782B (en) * | 2014-08-18 | 2015-12-30 | 上海交通大学 | Based on the valve free pump sucker that stacked radial pattern series-parallel connection compliant structure drives |
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2019
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Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998017332A2 (en) * | 1996-10-25 | 1998-04-30 | D'antonio Consultants International, Inc. | Hypodermic fluid dispenser |
| CN102836478A (en) * | 2006-10-26 | 2012-12-26 | 马林克罗特有限公司 | Medical fluid injector having a thermo-mechanical driver |
| CN201377412Y (en) * | 2009-04-24 | 2010-01-06 | 北京石油化工学院 | Single-film continuous transmission fluid piezoelectric pump |
| CN202108708U (en) * | 2011-06-24 | 2012-01-11 | 浙江师范大学 | Piezoelectric stack pump with sensor |
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