CN109821098B - Piezoelectric stack driving type infusion device - Google Patents
Piezoelectric stack driving type infusion device Download PDFInfo
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- CN109821098B CN109821098B CN201910187870.7A CN201910187870A CN109821098B CN 109821098 B CN109821098 B CN 109821098B CN 201910187870 A CN201910187870 A CN 201910187870A CN 109821098 B CN109821098 B CN 109821098B
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- 238000001802 infusion Methods 0.000 title claims abstract description 25
- 230000006835 compression Effects 0.000 claims abstract description 94
- 238000007906 compression Methods 0.000 claims abstract description 94
- 239000003814 drug Substances 0.000 claims abstract description 34
- 239000007788 liquid Substances 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 3
- 239000003570 air Substances 0.000 description 20
- 229940079593 drug Drugs 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 229910000906 Bronze Inorganic materials 0.000 description 2
- 229910052790 beryllium Inorganic materials 0.000 description 2
- ATBAMAFKBVZNFJ-UHFFFAOYSA-N beryllium atom Chemical group [Be] ATBAMAFKBVZNFJ-UHFFFAOYSA-N 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 239000010974 bronze Substances 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000010255 intramuscular injection Methods 0.000 description 2
- 239000007927 intramuscular injection Substances 0.000 description 2
- 238000010253 intravenous injection Methods 0.000 description 2
- 230000000750 progressive effect Effects 0.000 description 2
- 238000010254 subcutaneous injection Methods 0.000 description 2
- 239000007929 subcutaneous injection Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000599 controlled substance Substances 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
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Abstract
The invention relates to a piezoelectric stack driving type infusion device, and belongs to the field of medical instruments. The top of the base is provided with an inlet hole, a hole cavity communicated with the outlet hole through an outlet cavity and at least two body cavity groups consisting of body cavities; only one body cavity in each body cavity group is provided with an inlet cavity and an outlet hole, and other body cavities are only provided with vent holes; the diaphragm is pressed on the base by the main body, the bottom of the main body is provided with a guide hole group and a guide hole, the number of which is respectively equal to that of the body cavity group and the body cavities contained in the body cavity group, the guide holes and the body cavities have the same diameter and are symmetrically arranged at two sides of the diaphragm, and the diaphragm, the body cavities and the inlet valve form a compression cavity; compression cavities in the same cavity group are connected in parallel to form a compression cavity group, and the compression cavity groups are connected in series; the piezoelectric stack in the guide hole presses the piston on the diaphragm; a medicine bag consisting of a medicine cavity and an air cavity is arranged in the bag cavity at the top of the main body; the air cavity is communicated with the outlet hole through an air delivery pipe, and a flow valve and a needle head are arranged on a liquid delivery pipe of the medicine cavity; the deformation directions of the diaphragms in the same compression cavity group are the same, and the deformation directions of the diaphragms in two adjacent compression cavity groups are opposite.
Description
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to a piezoelectric stack driving type infusion device.
Background
The existing injection administration mainly comprises intravenous injection, intramuscular injection, subcutaneous injection and the like. Intravenous injection is also called infusion administration, and most of the existing infusion devices are composed of an infusion bottle, an infusion tube and an infusion support, wherein the infusion bottle is hung on the infusion support, flows by the self weight of liquid medicine and is injected into a blood vessel of a person through the infusion tube. This infusion mode brings about many problems in practical use: the flow is adjusted by a manual method, and the flow control precision is insufficient; the patient needs to lift the infusion bottle by others when walking or going to the toilet, and the like, so that the movement is inconvenient and the blood can flow back when the height of the infusion bottle is not enough; the patient or the nursing staff is required to watch for a long time, and if the completion of the infusion is not found in time, accidents can be caused; the liquid medicine contacts with air, and the pollution possibility exists when the ambient air is unclean. In addition to the above direct problems, the infusion time is sometimes shortened by reducing the amount of solution, increasing the infusion speed, and the like, which not only burdens the heart, but also affects the therapeutic effect: the most important disadvantage of intramuscular injection and subcutaneous injection, which inject drugs into muscle or subcutaneous tissue in a relatively short time, is that the difference of blood drug concentration is large in one injection period, which is not favorable for effective absorption and utilization of drugs because: most drugs have a better concentration range in human body, and have toxic and side effects when the concentration of the drugs is too high, and have no treatment effect when the concentration of the drugs is too low. Therefore, a miniature portable controlled drug delivery device or system that can prolong the drug injection time and maintain reasonable drug concentration is urgently needed in the medical field.
Disclosure of Invention
The invention provides a piezoelectric stack driving type infusion device, which comprises the following implementation schemes: the top of the base is provided with an inlet hole, a hole cavity communicated with the outlet hole through an outlet cavity and at least two body cavity groups formed by body cavities, and the number of the body cavities in each body cavity group is reduced in sequence from left to right; one body cavity in each body cavity group is provided with an inlet cavity and an outlet hole, and other body cavities are only provided with vent holes; the inlet cavity in the leftmost body cavity group is communicated with the inlet hole, and the outlet hole in the rightmost body cavity group is communicated with the outlet cavity; the air outlet holes in the same body cavity group are communicated with the air vent holes through the communicating holes, and the inlet cavities and the air outlet holes in the two left and right adjacent body cavity groups are communicated; the inlet and outlet cavities and valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve, and the valve plates are cantilever beam valves or butterfly valves; the main body is arranged on the base through screws and presses the diaphragm on the base, the bottom of the main body is provided with a guide hole group and a guide hole, the number of which is equal to that of the body cavity group and the body cavities contained in the body cavity group, the guide holes and the body cavities are equal to each other, the guide holes and the body cavities are symmetrically arranged on the upper side and the lower side of the diaphragm, a sealing ring is arranged between the diaphragm and the base, and the diaphragm, the body cavities and an inlet valve; compression cavities in the same cavity group are connected in parallel to form a compression cavity group, and the compression cavity groups are connected in series; the piezoelectric stack in the guide hole presses and connects the piston on the diaphragm, the piston is in a T-shaped structure, the small end of the piston is contacted with the diaphragm, and the side wall of the large end of the piston is contacted with the inner wall of the guide hole; the top of the main body is provided with a bag cavity, and a medicine bag consisting of a medicine cavity and an air cavity is arranged in the bag cavity; the air cavity is communicated with the outlet hole through an air delivery pipe, and a flow valve and a needle head are arranged on a liquid delivery pipe of the medicine cavity; in work, the deformation directions of the diaphragms in the same compression cavity group are the same, namely the piezoelectric stacks in the same guide hole group are extended or shortened, and the deformation directions of the diaphragms in two adjacent compression cavity groups are opposite; each compression cavity group is to gas entering air cavity through the gas-supply pipe after the gas is accumulated compression step by step, and the medicine chamber is extruded and increased to the air cavity volume, and the liquid medicine pressure in the medicine chamber increases and is discharged from transfer line and syringe needle, and the liquid medicine discharge amount can be adjusted through piezo-electric stack's drive voltage or flow valve.
Taking the infusion device with three compression cavity groups as an example, from right to left, the guide hole groups are sequentially defined as a first guide hole group, a second guide hole group and a third guide hole group, the body cavity groups are sequentially defined as a first body cavity group, a second body cavity group and a third body cavity group, the inlet valves are sequentially defined as a first inlet valve, a second inlet valve and a third inlet valve, the compression cavity groups are sequentially defined as a first compression cavity group, a second compression cavity group and a third compression cavity group, and then the specific working process is as follows: in the first half cycle, the piezoelectric stacks in the first guide hole group and the third guide hole group are shortened, the piezoelectric stacks in the second guide hole group are lengthened, the volumes of the first compression cavity group and the third compression cavity group are increased, the volumes of the second compression cavity group are reduced, the first inlet valve and the third inlet valve are opened, the second inlet valve and the outlet valve are closed, the first compression cavity group and the third compression cavity group suck gas, and the second compression cavity group discharges gas, which is a suction process; in the second half cycle, the piezoelectric stacks in the first guide hole group and the third guide hole group are extended, the piezoelectric stacks in the second guide hole group are shortened, the volumes of the first compression cavity group and the third compression cavity group are reduced, the volumes of the second compression cavity group are increased, the first inlet valve and the third inlet valve are closed, the second inlet valve and the second outlet valve are opened, the first compression cavity group and the third compression cavity group discharge gas, and the second compression cavity group sucks gas, which is a discharge process; in the suction and discharge processes, the gas undergoes the progressive accumulated compression of the compression cavity groups III, II and I, and the output pressure is gradually increased.
The inventionThe maximum gas storage pressure in the middle and air cavity is Pmax=P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, namely the ratio of the volume variation of the compression cavity to the volume of the compression cavity caused by the expansion and contraction deformation of the piezoelectric stack, beta is more than 1 and is the minimum value of the number ratio of the compression cavities contained in each adjacent compression cavity group, and n is more than or equal to 2 and is the number of the compression cavity groups; in order to obtain the maximum compression ratio, the optimal radius ratio of the small end to the large end of the piston is respectively 0.79, 0.65 and 0.55 when the diaphragm is beryllium bronze with the thickness of 0.1, 0.2 and 0.3mm, and the height of the compression cavity is the elongation of the piezoelectric stack under the action of voltage; when two adjacent compression cavity groups are communicated with each other, namely when a valve plate between the two adjacent compression cavity groups is opened, the volume variation of the compression cavity group containing a large number of compression cavities is not less than the volume variation of the compression cavity group containing a small number of compression cavities.
Advantages and features: the gas pressure can be greatly improved by utilizing an accumulative compression method; the gas is used for driving the liquid medicine, so that the transfusion speed is easy to be accurately controlled through the driving voltage, a hanging device is not needed, and the liquid medicine is convenient to move and carry; the liquid medicine does not contact with the air, the phenomena of liquid medicine pollution, gas entering blood vessels, blood backflow and the like can not occur, real-time watching is not needed, and the device is safe and reliable.
Drawings
FIG. 1 is a schematic view of the construction of an infusion set in accordance with a preferred embodiment of the present invention;
FIG. 2 is a cross-sectional view A-A of FIG. 1;
FIG. 3 is a schematic view of the infusion set in operation in accordance with a preferred embodiment of the present invention;
FIG. 4 is a schematic structural diagram of a main body according to a preferred embodiment of the present invention;
FIG. 5 is a bottom view of FIG. 4;
FIG. 6 is a schematic structural diagram of a base in accordance with a preferred embodiment of the present invention;
fig. 7 is a top view of fig. 6.
Detailed Description
The top of the base c is provided with an inlet hole c1, a hole cavity c3 communicated with an outlet hole c7 through an outlet cavity c6 and at least two body cavity groups Ci formed by body cavities c2, and the number of body cavities c2 in each body cavity group Ci is reduced in sequence from left to right; one body cavity c2 in each body cavity group Ci is provided with an inlet cavity c4 and an outlet hole c5, and the other body cavities c2 are only provided with vent holes c 8; the inlet chamber c4 in the leftmost body cavity group Ci communicates with the inlet port c1, and the outlet port c5 in the rightmost body cavity group Ci communicates with the outlet chamber c 6; the air outlet hole c5 in the same body cavity group Ci is communicated with the air vent hole c8 through a communication hole c9, and the inlet cavity c4 and the air outlet hole c5 in two left and right adjacent body cavity groups Ci are communicated; the inlet chamber c4 and the outlet chamber c6 and a valve plate t arranged in the inlet chamber c4 and the outlet chamber c6 form an inlet valve vi and an outlet valve v respectively, and the valve plate t is a cantilever beam valve or a disc valve; the bottom of the main body a is provided with a guide hole group Ai and a guide hole a2 which are respectively equal to the body cavity group Ci and the body cavities c2 contained in the body cavity group Ci in number, the diameter of the guide hole a2 is equal to the diameter of the body cavity c2, the main body a is arranged on a base c through screws and presses a diaphragm g on the base c, the guide hole a2 and the body cavities c2 are symmetrically arranged on the upper side and the lower side of the diaphragm g, a sealing ring is arranged between the diaphragm g and the base c, and the diaphragm g, the body cavities c2 and an inlet valve vi form; the compression chambers Y in the same body cavity group Ci are connected in parallel to form a compression chamber group Yi, and the compression chamber groups Yi are connected in series; the piezoelectric stack d in the guide hole a2 presses a piston e against a diaphragm g, the piston e is of a T-shaped structure, the small end of the piston e is in contact with the diaphragm g, and the side wall of the large end of the piston e is in contact with the inner wall of the guide hole a 2; the top of the main body a is provided with a capsule cavity a1, and a medicine bag b composed of a medicine cavity b1 and an air cavity b2 is arranged in the capsule cavity a 1; the air cavity b2 is communicated with the outlet hole c7 through an air conveying pipe, and a flow valve m and a needle head are arranged on a liquid conveying pipe q of the medicine cavity b 1; in work, the deformation directions of the diaphragms g in the same compression cavity group Yi are the same, namely the piezoelectric stacks d in the same guide hole group Ai are extended or shortened, and the deformation directions of the diaphragms g in two adjacent compression cavity groups Yi are opposite; each compression cavity group Yi accumulates and compresses the gas step by step and then enters an air cavity b2 through an air conveying pipe, the volume of the air cavity b2 is increased and extrudes a medicine cavity b1, the medicine liquid pressure in the medicine cavity is increased and is discharged from an infusion pipe q and a needle head, and the discharge amount of the medicine liquid can be regulated by the driving voltage or the flow valve m of the piezoelectric stack d.
In the invention, i in a guide hole group Ai, a body cavity group Ci, an inlet valve vi and a compression cavity group Yi represents a serial number from right to left, and i is 1, 2 and 3; taking an infusion device with three compression cavity groups Yi as an example, from right to left, the guide hole groups Ai are sequentially defined as guide hole groups a1, two a2 and three A3, the body cavity groups Ci are sequentially defined as body cavity groups C1, two C2 and three C3, the inlet valves vi are sequentially defined as inlet valves one v1, two v2 and three v3, and the compression cavity groups Yi are sequentially defined as compression cavity groups one Y1, two Y2 and three Y3, so that the specific working process is as follows: in the upper half cycle, the piezoelectric stacks d in the guide hole group I A1 and the guide hole group III A3 are shortened, the piezoelectric stacks in the guide hole group II A2 are lengthened, the volumes of the compression cavity group I Y1 and the compression cavity group III Y3 are increased, the volumes of the compression cavity group II Y2 are reduced, the inlet valves I1 and III V3 are opened, the inlet valves II V2 and the outlet valves II V are closed, the compression cavity group I Y1 and III Y3 suck gas, and the compression cavity group II Y2 discharges gas, so that the suction process is realized; in the second half cycle, the piezoelectric stacks d in the first guide hole group A1 and the third guide hole group A3 are extended, the piezoelectric stacks in the second guide hole group A2 are shortened, the volumes of the first compression cavity group Y1 and the third compression cavity group Y3 are reduced, the volumes of the second compression cavity group Y2 are increased, the first inlet valve v1 and the third compression cavity 3 are closed, the second inlet valve v2 and the outlet valve v are opened, the first compression cavity group Y1 and the third compression cavity group Y3 discharge gas, and the second compression cavity group Y2 sucks gas, so that the discharge process is carried out; during the suction and the discharge, the gas undergoes the progressive accumulated compression of the three Y3, two Y2 and one Y1 compression cavity groups, and the output pressure is gradually increased.
In the present invention, the maximum gas storage pressure in the gas chamber b2 is Pmax=P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, namely the ratio of the volume variation of the compression cavity Y caused by the expansion and contraction deformation of the piezoelectric stack d to the volume of the compression cavity Y, beta is more than 1 and is the minimum value of the number ratio of the compression cavities Y contained in each adjacent compression cavity group Yi, and n is more than or equal to 2 and is the number of the compression cavity groups Yi; in order to obtain the maximum compression ratio, the optimal radius ratio of the small end to the large end of the piston e is respectively 0.79, 0.65 and 0.55 when the diaphragm g is beryllium bronze with the thickness of 0.1, 0.2 and 0.3mm, and the height of a compression cavity is the elongation of the piezoelectric stack d under the action of voltage; when two adjacent compression cavity groups Yi are mutually communicated, namely when a valve plate t between the two adjacent compression cavity groups is opened, the volume variation of the compression cavity group Yi containing a large number of compression cavities Y is not less than the volume variation of the compression cavity group Yi containing a small number of compression cavities Y.
Claims (1)
1. A piezoelectric stack driving type infusion device is characterized in that: the top of the base is provided with an inlet hole, a hole cavity communicated with the outlet hole through an outlet cavity and at least two body cavity groups formed by body cavities, and the number of the body cavities in each body cavity group is reduced in sequence from left to right; one body cavity in each body cavity group is provided with an inlet cavity and an outlet hole, and other body cavities are only provided with vent holes; the inlet cavity in the leftmost body cavity group is communicated with the inlet hole, and the outlet hole in the rightmost body cavity group is communicated with the outlet cavity; the air outlet holes in the same body cavity group are communicated with the air vent holes through the communicating holes, and the inlet cavities and the air outlet holes in the two left and right adjacent body cavity groups are communicated; the inlet and outlet cavities and the valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve; the main body is arranged on the base and presses the diaphragm on the base, the bottom of the main body is provided with a guide hole group and a guide hole, the number of which is equal to that of the body cavity group and the body cavities contained in the body cavity group, the guide holes and the body cavities are respectively equal to that of the body cavity group, the diameters of the guide holes and the body cavities are equal, the guide holes and the body cavities are symmetrically arranged on the upper side and the lower side of the diaphragm, a sealing ring is arranged; compression cavities in the same cavity group are connected in parallel to form a compression cavity group, and the compression cavity groups are connected in series; the piezoelectric stack in the guide hole presses and connects the piston on the diaphragm, the piston is in a T-shaped structure, the small end of the piston is contacted with the diaphragm, and the side wall of the large end of the piston is contacted with the inner wall of the guide hole; the top of the main body is provided with a bag cavity, and a medicine bag consisting of a medicine cavity and an air cavity is arranged in the bag cavity; the air cavity is communicated with the outlet hole through an air delivery pipe, and a flow valve and a needle head are arranged on a liquid delivery pipe of the medicine cavity; in the working process, the deformation directions of the diaphragms in the same compression cavity group are the same, and the deformation directions of the diaphragms in two adjacent compression cavity groups are opposite; the maximum gas storage pressure in the gas cavity is Pmax=P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapIn order to obtain the efficiency coefficient, alpha is the compression ratio, beta is the minimum value of the number ratio of the compression cavities contained in each adjacent compression cavity group, and n is the number of the compression cavity groups.
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