CN109820070A - A kind of formula tea and preparation method thereof reducing blood uric acid - Google Patents
A kind of formula tea and preparation method thereof reducing blood uric acid Download PDFInfo
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Abstract
The invention discloses a kind of formula tea for reducing blood uric acid, the formula tea composition includes that drying lily, drying wax gourd, drying pawpaw, drying sponge gourd, green tea, drying chrysanthemum, Rosa roxburghii Tratt be dry, dried orange peel, particularly suitable for uric acid excretion, good figure and the Patients with Hyperuricemia of mixed type are not drunk, it can reduce the blood uric acid of patient, increase urine ph values, increase uric acid excretion amount in urine, alleviates or reduce arthralgia breaking-out.The formula tea ingredient is the food materials of integration of drinking and medicinal herbs, without any side effects, safely and effectively, for Patients with Hyperuricemia long-term use.Invention also provides the preparation method of the formula tea, various ingredients can be sufficiently mixed by this method, and simple to operation.
Description
Technical field
The invention belongs to functional food technical fields, and in particular to a kind of formula tea-drinking that can reduce human body blood uric acid
And preparation method thereof.
Background technique
In recent years, the illness rate of hyperuricemia increases year by year.It is estimated that the illness of China's general population's hyperuricemia
Rate is about 10%, suitable with the illness rate of diabetes；And China coast and developed area reach the illness of hyperuricemia
Rate is estimated to have reached or horizontal close to European and American developed countries 20% or more.Hyperuricemia totally presents high generation
Rate, rejuvenation, male be higher than women, the coastal fashion trend higher than interior ground, as a kind of common and with endangering extensively
Metabolic disease should attract great attention.
Hyperuricemia (HUA) refers under normal purine diet state, non-empty stomach serum uric acid level male twice on the same day
360 μm of ol/L of > 420 μm of ol/L, women >.
Uric acid in human body is derived partly from diet intake, partially by the purine compound of internal catabolism in liver
It generates, 2/3rds by kidney excretion, remaining is drained by alimentary canal, sweat gland of skin etc..Under normal circumstances, internal uric acid generates
Dynamic equilibrium is kept with excretion, it is all that the factor that uric acid generation is excessive and/or excretion is reduced is caused to can lead to hyperuricemia.
Hyperuricemia has the characteristics that the correlation of multi viscera harm.When blood uric acid is more than saturated concentration, urate crystals
Precipitation can directly stick, be deposited on the positions such as joint and surrounding soft tissue, renal tubule and blood vessel, chemotactic neutrophil leucocyte and macrophage
Cell；Discharge pro-inflammatory cytokine, metalloproteinase 9, hydrolase etc. after cell and crystal interaction, cause articular cartilage, sclerotin,
The damage of the active chronic inflammations such as kidney and endangium.Therefore generally believe that HUA is a variety of cardiovascular risk factors and correlation at present
The independent hazard factor of disease (metabolic syndrome, diabetes B, hypertension, cardiovascular event and death, chronic kidney disease etc.).
Clinically, the classification diagnosis method of hyperuricemia are as follows: after HUA patient's low purine diet 5d, leave and take urine inspection for 24 hours
Urine uric acid level is surveyed, while detecting serum uric acid level.Being divided HUA according to serum uric acid level and urine uric acid excretion situation is following three
Seed type: (1) uric acid excretion not good figure: uric acid excretion < 0.48mgkg-1·h-1, uric acid clearance < 6.2ml/min.(2)
Uric acid generated many types of: uric acid excretion > 0.51mgkg-1·h-1, uric acid clearance >=6.2ml/min.(3) mixed type: uric acid
Excretion > 0.51mgkg-1·h-1, uric acid clearance < 6.2ml/min.[note: uric acid clearance (Cua)=urine uric acid × every point
Clock urine volume/blood uric acid] consider influence of the renal function to uric acid excretion, it is corrected with creatinine clearance rate (Ccr), last basis
Cua/Ccr value carries out parting to HUA.When Cua/Ccr value > 10%, generated for uric acid many types of；When Cua/Ccr value < 5%,
For uric acid excretion not good figure；It is mixed type when Cua/Ccr value is 5%~10%.Clinical study results show, 90% original
Hair property HUA belongs to uric acid excretion not good figure.
Currently, include general treatment in the treatment method of hyperuricemia, life style guidance therein and appropriate alkali
Change urine, all has close relationship with dietetic nutrition.One Meta analysis shows that dietary therapy can about reduce by 10%~
18% blood uric acid value reduces blood uric acid value by 70~90 μm of ol/L.Daily urine volume control is in 1500ml or more and appropriate alkalization
Urine controls urine ph values 6.2~6.9, be conducive to urate crystal dissolution and be discharged from urine.
Summary of the invention
The object of the present invention is to provide a kind of formula tea that can reduce blood uric acid.The tea can be substantially reduced antihyperuricemic
The blood uric acid value of disease patient improves the pain symptom of Patients with Hyperuricemia.
To achieve the goals above, following technical scheme is inventor provided.
A kind of formula tea reducing blood uric acid, composition includes: drying lily, drying wax gourd, drying pawpaw, drying
Sponge gourd, green tea, drying chrysanthemum, Rosa roxburghii Tratt be dry, dried orange peel.
The formula tea of above-mentioned reduction blood uric acid, based on parts by weight, composition includes: drying lily 1-3 parts, drying
4-8 parts of wax gourd, pawpaw 1-3 parts drying, sponge gourd 3-6 parts drying, 1-2 parts of green tea, chrysanthemum 1-4 parts drying, Rosa roxburghii Tratt is 1-4 parts dry, old
1-2 parts of skin.
The formula tea of above-mentioned reduction blood uric acid, based on parts by weight, composition is preferred are as follows: 1 part of drying lily, drying
4 parts of wax gourd, 1 part of drying pawpaw, 3 parts of drying sponge gourd, 1 part of green tea, 1 part of drying chrysanthemum, Rosa roxburghii Tratt are 1 part, 1 part of dried orange peel dry.
The formula tea of above-mentioned reduction blood uric acid, based on parts by weight, composition is preferred are as follows: 3 parts of drying lily, drying
8 parts of wax gourd, 3 parts of drying pawpaw, 6 parts of drying sponge gourd, 2 parts of green tea, 4 parts of drying chrysanthemum, Rosa roxburghii Tratt are 3 parts, 2 parts of dried orange peel dry.
Drying lily of the present invention refers to the lanzhou lily in collecting period picking, dried lily made of drying.Its property is micro-
It is cold, sweet in flavor, slight bitter, distributed in heart and lung channels.There is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.Rich in bioactivity such as colchicins in lily
Substance mitigates the excessively high caused inflammatory reaction of blood uric acid.
Drying wax gourd of the present invention refers to wax gourd cleaning, peeling, deseeding, slitting, is ground into what drying after pureed obtained
Wax gourd dry powder.Because wax gourd water content is higher, use this technique not only can be with rapid dehydration, but also more water soluble vitamins lifes can be retained
Element and phytochemical.Wax gourd cold nature, sweet in flavor, light, return lung, large intestine, small intestine, bladder meridian.There is diuresis, heat-clearing, promotes the production of body fluid, detoxifies
The effect of.Wax gourd is the high food of basicity, and uric acid salt solubility can be improved, conducive to the discharge of uric acid；Wax gourd also has diuresis
Effect, can promote the excretion of uric acid；Wax gourd also has the function of clearing heat and detoxicating simultaneously, can make free movement of the bowels, to promote
The excretion of uric acid.
The raw material of drying pawpaw of the present invention be Xuancheng's pawpaw, clean, remove flesh, slice after dry.Its is warm-natured, taste
Acid returns liver, the spleen channel.There is the effect of relaxing tendons and activating collaterals, removing dampness to restore normal functioning of the stomach.Xuancheng's pawpaw is the high food of basicity, contains a large amount of dimension life
Plain C, superoxide dismutase and phytochemical etc., there is resisting oxidation and delaying senility, are conducive to the excretion of uric acid.
Drying sponge gourd of the present invention refers to sponge gourd cleaning, peeling, deseeding, slitting, is ground into what drying after pureed obtained
Sponge gourd dry powder.Because sponge gourd water content is higher, use this technique not only can be with rapid dehydration, but also more water soluble vitamins lifes can be retained
Element and phytochemical.Sponge gourd is cool in nature, sweet in flavor, return lung, liver, stomach, large intestine channel.There is the effect of clearing heat and eliminating phlegm, removing pattogenic heat from the blood and toxic material from the body.Sponge gourd
It is the high food of basicity, the solubility of lithate can be improved, is conducive to uric acid and is discharged；Simultaneously also have the function of it is clearing heat and detoxicating,
It can make free movement of the bowels, promote uric acid excretion.
Drying chrysanthemum of the present invention is the dry capitulum of composite family herbaceos perennial chrysanthemum, and what the present invention selected is
Florists Chrysould likehemum kind, raw material are the chrysanthemum for originating in Anhui Province, Shexian County, Huangshan, also referred to as emblem chrysanthemum.Its cold nature, sweet in flavor, bitter, return lung, liver
There is the effect of dispelling wind and heat, calming the liver and improving eyesight, removing toxicity for detumescence, anti-inflammatory analgetic.There is clearing heat and detoxicating effect simultaneously, can make
Free movement of the bowels promotes uric acid excretion.Florists Chrysould likehemum vitamin B rich in, Flavonoid substances, can be anti-oxidant, anti-inflammatory, promotes uric acid
Dissolution and excretion.
The dry raw material of Rosa roxburghii Tratt of the present invention is the Rosa roxburghii Tratt (Rosa roxburghii Tratt.) for originating from Guizhou Province western part,
Cleaned, de- thorn dries gained after cutting half, deseeding.Its is cool in nature, sweet in flavor, sour, returns spleen, stomach, large intestine channel, has clearing away summerheat, is good for
The effect of stomach helps digestion.The dry vitamin C being rich in of Rosa roxburghii Tratt and Flavonoid substances can promote the dissolution and excretion of lithate in tissue；Together
When have anti-oxidant, anti-inflammatory effect.It has been reported that raw element C can be by the activity of Reverse transcriptase binding site to increase
Add the kidney excretion of uric acid and reduces uric acid in the reabsorption of kidney.
Green tea of the present invention refer to the bud of tea tree Camellia sinensis (Linnaeus.) O.Kuntze, leaf,
Tender stem is raw material, green tea made of the processes such as finished, rubbed, dried.Green tea remains the natural materials of fresh leaf, the tea contained
Polyphenol, catechin, chlorophyll, caffeine, amino acid, vitamins and other nutritious components, there is diuresis to recover from fatigue, lower blood-fat and reduce weight the effects of,
Be conducive to the dissolution and excretion of lithate.
Dried orange peel in the formula tea of the present invention for reducing blood uric acid, warm-natured, acrid flavour, hardship, returns spleen, lung channel have qi-regulating
In tune, it is eliminating dampness and eliminating phlegm the effect of.The bioflavonoid being rich in dried orange peel can promote the dissolution and excretion of lithate in tissue.
Invention also provides the preparation method of the formula tea of above-mentioned reduction blood uric acid, operating procedure includes:
A. it is milled: the drying lily of formula ratio, drying pawpaw, green tea, drying chrysanthemum, Rosa roxburghii Tratt being done, dried orange peel pours into high speed
Interior crushing in pulverizer obtains primary mixed powder, spare；
B. it is sieved: drying wax gourd and drying sponge gourd being crossed into 80-120 mesh respectively, obtain white gourd powder, Luffa powder, it is spare；
C. it mixes: the primary of formula ratio being mixed into powder, white gourd powder, Luffa powder are placed in Multidimensionblender and mix to get to matching
Square tea.
In above-mentioned preparation method, the partial size of primary mixed powder is preferably 80-120 mesh in step A；In step C, the mixed time
It is preferred that 10-20min.
It is provided by the present invention formula tea preparation method, be milled step in, dried lily, green tea, chrysanthemum are sweet in flavor cold in nature, thorn
The dry sweet,sour and puckery taste of pears, Xuancheng's pawpaw acid, temperature, dried orange peel is bitter, warm-natured, and six kinds of raw material nature and flavor are similar, and no restriction or checking relation in five elements repels each other, and auxiliary mutually
It helps, it is common to process the effect for being easy to give full play to raw material.It in mixing step, is mixed using Multidimensionblender, Ke Yibao
Ingredient is uniform, uniformly in card formula tea, can give full play to curative effect.
Formula tea provided by the present invention can be distributed into as needed in PET nonwoven fabric tea bag, be convenient for carrying and drunk.
Formula tea provided by the present invention particularly suitable for uric acid excretion, do not drink by good figure and the Patients with Hyperuricemia of mixed type
With.Specific Patients with Hyperuricemia is diagnosed using this formula tea-drinking, reduction blood uric acid is presented with, increases urine ph values, increase
Add uric acid excretion amount in urine, alleviates or reduce arthralgia breaking-out, the effect of losing weight, to the patient for partially having constipation history
There are also the effects for improving constipation.During taking the tea-drinking, other significant complications such as no gastrointestinal discomfort.The tea-drinking ingredient is equal
Without any side effects for the food materials of integration of drinking and medicinal herbs, safely and effectively, Patients with Hyperuricemia can often be drunk, long-term drinking effect
More preferably.
Specific embodiment
Content of the present invention is further described in detail combined with specific embodiments below.
Embodiment 1
Inventor investigates the application effect of the formula tea provided by the present invention for reducing blood uric acid, concrete condition
It is as follows:
One, the screening of subject
(1) it has been diagnosed as hyperuricemia；
(2) absent cardiovascular risk factor or cardiovascular disease；
(3) anti-trioxypurine drug therapy is not carried out；
(4) without other Chronic Non-Communicable Diseases.
Taboo: the needs such as heart failure, renal failure, cirrhotic ascites strictly limit the people of liquid feeding amount；To this
The people of ingredient allergy in product.
Two, drinking method
Tea-drinking is packed, every time 1 bag (26g), 2 times a day, every bag is steeped 5 minutes with 100 DEG C of water are stewing, i.e., drinkable, every tea bag
Drink can be continuously with water to 2000ml.1 month is 1 course for the treatment of.
Ganderwa: early postprandial 1~4h；1~4h after lunch.
Three, Testing index
Respectively detection subject drink first 1 day, drink latter 15th day, drinking latter 30th day, drink rear 45th day weight,
Blood uric acid value, urine ph values, uric acid is quantitative for 24 hours.
Four, process and result are tested
Inventor has carried out two groups altogether and has drunk test.
First group:
The composition of first group of subject institute drink tea are as follows: 1 part of drying lily, 4 parts of drying wax gourd, 1 part of drying pawpaw,
3 parts of drying sponge gourd, 1 part of green tea, 1 part of drying chrysanthemum, Rosa roxburghii Tratt are 1 part, 1 part of dried orange peel dry.The mesh number of ingredient is 80 mesh, mixing
10min。
The patient for sharing 5 hyperuricemias, which is voluntarily selected in, becomes subject.5 subjects previously have the first plantar toe pass
Panic attacks history is saved, there are 1 subject in seizure frequency < 7 day in taking tea-drinking the 2nd day the first plantar toe of appearance within this experimental period
Arthralgia breaking-out, remaining time, remaining subject was within entire experimental period without breaking-out without breaking-out.
Within experimental period, the equal without infectious diseases of 5 subjects occur.
During test, the gastrointestinal symptom of subject is also observed, Nausea and vomiting does not occur, previously there are the 4 of constipation history
Apparent improvement has occurred in example subject, constipation.
The test result of first group of subject is as shown in Table 1 and Table 2.
Table 1
To specific Patients with Hyperuricemia is diagnosed it can be seen from data in table 1, in the unchanged feelings of original eating habit
Under condition, this formula tea-drinking is drunk, within the observation period, with the extension of Time of Administration, weight can be gradually decreased, reduce blood urine
Acid increases urine ph values, increases uric acid excretion amount in urine, alleviates or reduce the effect of arthralgia breaking-out.Taking the tea
When drinking by 15 days, although blood uric acid value not up to normal level, is substantially reduced before relatively taking；Urine ph values are obviously improved, base
Originally reach normal；Uric acid excretion amount obviously increases earlier above for 24 hours, but uric acid excretion amount is still below standard；Weight is also substantially reduced earlier above.
When continuously taking the tea-drinking by 30 days, blood uric acid, urine ph values and uric acid excretion amount reaches normal level, weight for 24 hours
It is substantially reduced earlier above.When being further continued for taking by 45 days, blood uric acid, urine ph values and uric acid excretion amount is still within normal shape for 24 hours
State changes less when compared with 30 days, but weight is still in a slight decrease earlier above.It can be seen that formula tea provided by the present invention urinates height
Acidaemia patient, index of correlation can be improved by drinking 15 days, can reach optimum efficiency with 30 days, long-term drinking can maintain best effective
Fruit.
Table 2
| Subject | Nauseous (secondary) | It vomits (secondary) | Abdominal distension (secondary) | Diarrhea (secondary) | Constipation (secondary) |
| Subject 1 | 0 | 0 | 0 | 0 | 0 |
| Subject 2 | 0 | 0 | 0 | 1 | 0 |
| Subject 3 | 0 | 0 | 0 | 0 | 0 |
| Subject 4 | 0 | 0 | 0 | 0 | 0 |
| Subject 5 | 0 | 0 | 1 | 0 | 0 |
Second group:
The composition of second group of subject's drink tea are as follows: 3 parts of drying lily, 3 parts of drying pawpaw, does at 8 parts of drying wax gourd
6 parts of throwing melon, 2 parts of green tea, 4 parts of drying chrysanthemum, Rosa roxburghii Tratt are 3 parts, 2 parts of dried orange peel dry.The mesh number of ingredient is 100 mesh, mixing
20min。
The patient for sharing 5 hyperuricemias, which is voluntarily selected in, becomes subject.5 subjects previously have the first plantar toe pass
Save panic attacks history, seizure frequency < 7 day, without joint panic attacks within this experimental period.
Within experimental period, the equal without infectious diseases of 5 subjects occur.
During test, the gastrointestinal symptom of subject is also observed, Nausea and vomiting does not occur, previously there are the 3 of constipation history
Apparent improvement has occurred in example subject, constipation.
The test result of second group of subject is as shown in Table 3 and Table 4.
Table 3
To specific Patients with Hyperuricemia is diagnosed it can be seen from data in table 3, in the unchanged feelings of original eating habit
Under condition, this formula tea-drinking is drunk, within the observation period, with the extension of Time of Administration, weight can be gradually decreased, reduce blood urine
Acid increases urine ph values, increases uric acid excretion amount in urine, alleviates or reduce the effect of arthralgia breaking-out.Taking the tea
When drinking by 15 days, there are 3 patient's blood uric acid value up to normal level, although 2 not up to normal levels, obvious drop before relatively taking
It is low；Urine ph values are obviously improved, and reach desired quantity, this group of patient is during taking tea-drinking, than first group patient of urine ph values
It is universal higher, show that the alkalization degree of this group of Urine in Patients is higher；Uric acid excretion amount obviously increases earlier above for 24 hours, the urine of 4 patients
Sour excretion is up to standard, and the uric acid excretion amount of 1 patient is also close to up to standard；Weight is also substantially reduced earlier above.Continuously taking the tea
When drinking by 30 days, blood uric acid, urine ph values and uric acid excretion amount reaches normal level for 24 hours, weight is also substantially reduced earlier above.Again
When continuing to take by 45 days, blood uric acid, urine ph values and uric acid excretion amount is still within normal condition for 24 hours, compared with 30 days Shi Bianhua
Less, but weight is still in a slight decrease earlier above, it is seen that the tea-drinking, which improves high lithemia to Patients with Hyperuricemia, at least to be needed to drink 30 days
To reach optimum efficiency.It can be seen that formula tea provided by the present invention is to Patients with Hyperuricemia, phase can be improved by drinking 15 days
Index is closed, can reach optimum efficiency with 30 days, long-term drinking can maintain optimum efficiency.
Compared with the test data of first group of patient, second group of patient more can rapidly reduce blood uric acid, alkalized urine,
Increase uric acid excretion amount.
Table 4
| Subject | Nauseous (secondary) | It vomits (secondary) | Abdominal distension (secondary) | Diarrhea (secondary) | Constipation (secondary) |
| Subject 6 | 0 | 0 | 0 | 0 | 0 |
| Subject 7 | 0 | 0 | 0 | 0 | 0 |
| Subject 8 | 0 | 0 | 0 | 0 | 0 |
| Subject 9 | 0 | 0 | 0 | 0 | 0 |
| Subject 10 | 0 | 0 | 0 | 0 | 0 |
Claims (9)
1. a kind of formula tea for reducing blood uric acid, which is characterized in that composition includes: drying lily, drying wax gourd, drying wood
Melon, drying sponge gourd, green tea, drying chrysanthemum, Rosa roxburghii Tratt be dry, dried orange peel.
2. a kind of formula tea for reducing blood uric acid according to claim 1, which is characterized in that based on parts by weight, ingredient
Composition includes: drying lily 1-3 parts, wax gourd 4-8 parts drying, pawpaw 1-3 parts drying, sponge gourd 3-6 parts drying, 1-2 parts of green tea, does
Chrysanthemum 1-4 parts processed, Rosa roxburghii Tratt does 1-4 parts, 1-2 parts of dried orange peel.
3. a kind of formula tea for reducing blood uric acid according to claim 1, which is characterized in that based on parts by weight, ingredient
Composition include: 1 part of drying lily, 4 parts of drying wax gourd, 1 part of drying pawpaw, 3 parts of drying sponge gourd, 1 part of green tea, 1 part of drying chrysanthemum,
Rosa roxburghii Tratt is 1 part, 1 part of dried orange peel dry.
4. a kind of formula tea for reducing blood uric acid according to claim 1, which is characterized in that based on parts by weight, ingredient
Composition include: 3 parts of drying lily, 8 parts of drying wax gourd, 3 parts of drying pawpaw, 6 parts of drying sponge gourd, 2 parts of green tea, 4 parts of drying chrysanthemum,
Rosa roxburghii Tratt is 3 parts, 2 parts of dried orange peel dry.
5. it is according to claim 1 it is a kind of reduce blood uric acid formula tea, which is characterized in that the drying wax gourd refer to by
Wax gourd peeling, is ground into the wax gourd dry powder dried after pureed at deseeding.
6. it is according to claim 1 it is a kind of reduce blood uric acid formula tea, which is characterized in that the drying sponge gourd refer to by
Loofah peeling, is ground into the sponge gourd dry powder dried after pureed at deseeding.
7. a kind of preparation method of formula tea for reducing blood uric acid as described in claim 1, which is characterized in that operating procedure packet
It includes:
A. it is milled: the drying lily of formula ratio, drying pawpaw, green tea, drying chrysanthemum, Rosa roxburghii Tratt being done, dried orange peel pours into high speed and crushes
Interior crushing in machine obtains primary mixed powder, spare；
B. it is sieved: drying wax gourd and drying sponge gourd being crossed into 80-120 mesh respectively, obtain white gourd powder, Luffa powder, it is spare；
C. it mixes: the mixed powder of the primary of formula ratio, white gourd powder, Luffa powder being placed in Multidimensionblender and mixed to get formula tea is arrived.
8. a kind of preparation method of formula tea for reducing blood uric acid according to claim 7, which is characterized in that in step A
The partial size of the primary mixed powder is 80-120 mesh.
9. a kind of preparation method of formula tea for reducing blood uric acid according to claim 7, which is characterized in that in step C
The mixed time is 10-20min.
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| CN113908173A (en) * | 2020-07-11 | 2022-01-11 | 南京雷德蒙德农业科技有限公司 | Composition for reducing uric acid and preparation method thereof |
| CN112121144A (en) * | 2020-09-20 | 2020-12-25 | 武汉宏博云智生物科技有限公司 | Roxburgh rose composition and preparation method and application thereof |
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