CN109806334A - Join stilbene kidney tonifying diabetes pill - Google Patents
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- CN109806334A CN109806334A CN201910295635.1A CN201910295635A CN109806334A CN 109806334 A CN109806334 A CN 109806334A CN 201910295635 A CN201910295635 A CN 201910295635A CN 109806334 A CN109806334 A CN 109806334A
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Abstract
The invention discloses ginseng stilbene kidney tonifying diabetes pills, are related to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine for treating diabetes and preparation method.Composition: American Ginseng 28~32, pilose antler 4~6, Radix Astragali 46~54, Radix Rehmanniae 28~32, mantis egg-case 18~22, Radix Ophiopogonis 18~22, pulp of dogwood fruit 18~22, Chinese yam 18~22, the fruit of glossy privet 18~22, radix scrophulariae 18~22, radices trichosanthis 18~22, Semen Cuscutae 18~22, Radix Paeoniae Alba 28~32, river connect 9~11, tortoiseshell 18~22, fructus lycii 18~22；Preparation process: (one) impregnates twice；(2) it is evaporated, is ground into medicinal powder；(3) it is mixed according to medicinal powder with lactose, adds ethanol wet agent, it is dry, it is sieved, drug is made in sealing, packaging.The present invention solves Chinese medicine there are curative effects not lasting, the big problem of toxicity for the treatment of diabetes.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine for treating diabetes and preparation method.
Background technique
It steps into 21 century, diabetes, which have become, the third-largest after tumour, cardiovascular disease seriously threatens human health
Chronic Non-Communicable Diseases.Even to this day, the pathogenic factor and pathogenesis of DM is still not clear, and clinical manifestation is chronic sustained
Property blood sugar concentration increase, mostly with endocrine dysbolism be its characteristic feature.Advanced diabetes are easy to cause nervous system, view
The multiple complications such as nethike embrane, heart and brain kidney and blood vessel.
With the rapid development of China's economic society, the daily life style of people and dietary structure are changing,
The disease incidence of diabetes is obviously improved, and especially in the coastal cities of the prosperity such as Shanghai, Beijing and Guangdong, disease incidence has been up to
10%.Whole world diabetic about 1.5 hundred million people, wherein China patient amount be greater than 40,000,000, have become after India it
Second place of the world afterwards.World Health Organization predicts to will be up to 3.5 hundred million people to whole world diabetic in 2025.The structure of diet,
The reduction of daily life style variation and physical training has become the major reason that diabetes morbidity increases.
Diabetic condition is touching refractory, causes potential threat to people's health, equally increases to society huge
Financial burden.It can be seen that the prevention and treatment dynamics for increasing diabetes has become current urgent need.Doctor trained in Western medicine is directed to diabetes
Pathogenesis, though the antidiabetic drugs such as the insulin sensitizer developed and developed, alpha-glucosidase inhibitor, biguanides and sulfonylureas
Right curative effect affirmative, but the side effects such as generally existing drug resistance, gastrointestinal reaction and liver, Nephrotoxicity.
TCM Treatment of Diabetes is with a long history, has oneself original opinion to onset diabetes reason and pathogenesis
And theoretical thought.But at present for this purpose, Chinese medicine there are curative effects not lasting, the big disadvantage of toxicity for the treatment of diabetes now.
Summary of the invention
The present invention provides ginseng stilbene kidney tonifying diabetes pill, and the present invention solves the Chinese medicine for the treatment of diabetes, and that there are curative effects is not lasting,
The big problem of toxicity.
To solve the above problems, the present invention adopts the following technical scheme: joining stilbene kidney tonifying diabetes pill, by following mass parts ratio
Raw material composition: American Ginseng 28~32, pilose antler 4~6, Radix Astragali 46~54, Radix Rehmanniae 28~32, mantis egg-case 18~22, Radix Ophiopogonis 18~
22, pulp of dogwood fruit 18~22, Chinese yam 18~22, the fruit of glossy privet 18~22, radix scrophulariae 18~22, radices trichosanthis 18~22, Semen Cuscutae 18~22,
Radix Paeoniae Alba 28~32, river connect 9~11, tortoiseshell 18~22, fructus lycii 18~22；
Preparation process:
(1) above-mentioned medicinal material is impregnated twice；It is impregnated for the first time with 18~22 times of water measured 0.~1.2h of reflux, collects medical fluid；The
Secondary immersion is the dregs of a decoction with 18~22 times of 0.8~1.2h of the water measured reflux；
(2) medicinal material of immersion is evaporated, is ground into medicinal powder；
(3) it being mixed with lactose according to the mass ratio of 1:1.3~1.7 according to medicinal powder, adds ethanol wet agent, ethanol consumption is 0.35~
0.45ml ethyl alcohol/g mixed powder, it is dry, it is sieved, drug is made in sealing, packaging.The concentration of ethanol wet agent used be 70~
90%。
The function and effect of drug of the present invention:
1, monarch drug in a prescription: Radix Astragali returns spleen, lung two pass through, and sweet in flavor, slightly warm in nature has effects that QI invigorating Wen Yang promotes the production of body fluid, and just have in " Bie Lu " pair
The Radix Astragali record for controlling diabete: " it is deficient to mend husband, exhaustion or lesion of the five internal organs Lei Shou.Quench the thirst ... ...." American Ginseng returns spleen, the heart, the warp of kidney three, taste
It is sweet slight bitter, cold in nature, have effects that clearing heat and promoting fluid, enriching yin boost qi, to the correlation of American Ginseng drug effect in " Records of Tradition Chinese and Western Medicine in Combination "
Record is mentioned, and the American Ginseng function cool in nature for but having help, all desire QI invigorating, all can be with American Ginseng instead of without the warm-natured person of pleasant ginseng.
2, ministerial drug: Radix Rehmanniae: it is sweet, it trembles with fear.Shennong's Herbal: " main folding falls ..., fills out marrow, by blood-arthralgia, long muscle ... eliminating impediment ".Clothes
Can removing heat from blood, benefiting yin promote the production of body fluid, and control scorching quench one's thirst.The benefits of clinical application is extremely wide, and Chinese medicine often takes its nourishing Yin and clearing heat is used for diabetes
Treatment.Radix Ophiopogonis grows lung stomach again and American Ginseng shares and walk kidney water, and Jinsui River lung kidney mutually helps to slake thirst and help produce saliva and moisturize.Pulp of dogwood fruit gas
Flat, sour, slightly warm in nature returns kidney, liver two to pass through, and has the effect of mending smart, supporing yang, kidney-nourishing, for the product of flat tonifying yin sun, and is nourishing liver and kidney
Key medicine.Chinese yam is sweet in flavor, mild-natured, can supplementing the kidney to control the nocturnal, moistening lung nourishing the stomach tonifying spleen, the phase for early thering is Chinese yam to control diabete in classic medicine writings
Close and discuss, record in " book on Chinese herbal medicine is stated " its it is available control consumptive disease fever and disappear illness, the interior perverse trend of its main the five internal organs is referred in Shennong's Herbal, is hankered
Diabete.The yin essence of Chinese yam tonifying spleen again, the yang-energy of Radix Astragali tonifying spleen again, the leakage of two medicine sharings is turbid, beneficial spleen essence, helps transporting and transforming function of the spleen and stomach, removes
But the sign of glucose in urine.The fruit of glossy privet returns kidney, liver two to pass through, bitter, sweet, cool in nature, can clearing deficient heat, tonifying kidney and nourishing liver improving eyesight, " legendary god of farming's book on Chinese herbal medicine
Through " it is medical circles' stem drug monograph in China, wherein fruit of glossy privet five viscera settling, bowl spares, the effect for supporting spirit are referred to, it can be except hundred
Disease, long-term use can make personal Qiang Tijian, promote longevity.Radix scrophulariae is medicinal first recorded in Shennong's Herbal, cold nature, sweet in flavor,
Bitter, salty, return lung, spleen, kidney channel have clearing heat and cooling blood, and nourishing yin and lessening fire, detoxicating and resolving a mass function, clinic is mainly used for heat evil and enters blood system
Battalion point, impairment of yin polydipsia, the treatment of the deep red equal cards of body fluid deficiency tongue, modern clinical research show its with antimicrobial antiphlogistic, antitumor, liver protection,
Antipyretic-antalgic improves the effects of microcirculation and capillary permeability.
3, adjuvant: Radix Paeoniae Alba return liver warp, sour hardship, cold nature have and hold back negative essence, enrich blood, Pinggan Yang, the function for delaying liver analgesic
Effect.Pilose antler returns liver, kidney two warp, and taste is salty, sweet, warm-natured, being capable of warm kidney sun, torr sore poison, coordinating Chong and Conception Vessels, replenishing essence of enriching blood, strong muscles and bones.
Compendium of Material Medica refers to that pilose antler is available to be controlled in all deficient property diseases.Tortoiseshell taste is salty, sweet, cold in nature, has replenishing blood for nourishing heart, strong muscle
The effect of bone, kidney tonifying, benefiting yin Pingyang, " a supplement to augmented materia medica " deficiency for saying tonifying yin blood on the books to tortoiseshell can be with controlling overstrain, four
Myasthenia of limbs.Mantis egg-case is a conventional Chinese medicine, sweet in flavor, salty, mild-natured.Enter liver and kidney channel.Has the effect of kidney tonifying, controlling nocturnal emission with astringent drugs.The coptis has clear
Hot purging intense heat, promote the production of body fluid to quench thirst, detumescence and apocenosis the effect of, for the basic pathogenesis that the deficiency of Yin of quenching one's thirst is scorching, SUN Si miao 5 Radix Rehmanniae of the coptis,
Treatment is quenched one's thirst.The first Diabetes decoction of Holy Benevolent Prescriptions 211, common front three Chinese medicine have the coptis.Radices trichosanthis: it is sweet, bitter, enter lung stomach meridian, has
Have clearing heat-fire, promote the production of body fluid to quench thirst, detumescence and apocenosis the effect of.Shennong's Herbal speech: " master quenches one's thirst ".
Semen Cuscutae property acrid-sweet flavor is flat, can nourishing liver and kidney, benefiting quintessence, hard muscles and bones, benefiting energy, the strong people of fertilizer.To commonly use traditional tonic medicine,
With nourishing liver and kidney, astringent sperm contracting urine, miscarriage prevention, improving eyesight and other effects.Fructus lycii, name comes from Shennong's Herbal, sweet in flavor, mild-natured,
Mainly return liver, kidney, lung channel, have effects that nourishing liver and kidney, benefiting shrewd head and moistening lung, can be used for treating because of kidney deficiency and liver, lung
All diseases caused by deficiency of the kidney is empty, the medicinal time is more early, has more than 3000 years history so far from " combining in luxuriant Qi ", is to obtain the Ministry of Public Health batch at present
Quasi- dual-purpose of drug and food food, have hypoglycemic, anti-fatty liver, antitumor, antiatherosclerosis, anti-aging, resisting stress with
And enhance the effects of immune.
With Radix Astragali, American Ginseng in formula, replenish qi to invigorate the spleen, nourishing Yin and promoting production of body fluid is monarch altogether；Chinese yam, pulp of dogwood fruit, mantis egg-case take a tonic or nourishing food to build up one's health liver
The yin of spleen kidney, and can controlling nocturnal emission with astringent drugs arresting seminal emission, Radix Rehmanniae, Radix Ophiopogonis clear and rich lung stomach, body fluid of living again.Six medicines be harmonious kidney tonifying, essence replenishing, hold back yin rise saliva be
For minister, 5 Yishen Jianpi of the monarch and his subjects' phase, solid protection congenital essence-QI, and the source of the cultivation trough day after tomorrow.Assistant is with the fruit of glossy privet, radix scrophulariae, Huang
Even clearind deficient heat, tonifying kidney and nourishing liver；Radices trichosanthis, Radix Paeoniae Alba promote the production of body fluid to quench thirst, yin is held back in blood-nourishing, pilose antler nourishing and suppressing Yang, enriching kidney essence, make a general survey of complete
The effect of side, compatibility is precise and appropriate, plays strengthening spleen, tonifying kidney supplementing qi and nourishing yin altogether.
Chinese medicine of the invention is processed by a variety of genuine rare traditional Chinese medicine science, has a nourishment for vitality, invigorating Qi and tonifying kidney it
Function, for treating diabetes, by curative for effect in clinical application.Joining stilbene kidney tonifying diabetes pill is in long-term clinical practice, largely
On the basis of zoopery, for the prescription that the pathogenic characteristic of type-2 diabetes mellitus is intended certainly, the function with strengthening spleen, tonifying kidney supplementing qi and nourishing yin
Effect.It is absolutely proved by largely studying, ginseng stilbene kidney tonifying diabetes pill curative effect is lasting, and cheap, toxicity is small, can more targets
Point plays its therapeutic effect by all kinds of means, has become the effective way of prevention and treatment diabetes and its complication.
Specific embodiment
The present invention is described in detail with optimal embodiment below.
Embodiment one
Join stilbene kidney tonifying diabetes pill, is made of the raw material of following mass parts ratio: American Ginseng 28~32, pilose antler 4~6, Radix Astragali 46~
54, Radix Rehmanniae 28~32, mantis egg-case 18~22, Radix Ophiopogonis 18~22, pulp of dogwood fruit 18~22, Chinese yam 18~22, the fruit of glossy privet 18~22, it is profound
Ginseng 18~22, radices trichosanthis 18~22, Semen Cuscutae 18~22, Radix Paeoniae Alba 28~32, river connect 9~11, tortoiseshell 18~22, fructus lycii 18~
22；
Preparation process:
(1) above-mentioned medicinal material is impregnated twice；It is impregnated for the first time with 18~22 times of water measured 0.~1.2h of reflux, collects medical fluid；The
Secondary immersion is the dregs of a decoction with 18~22 times of water measured 0.8~1.2h of reflux, collects medical fluid, merges medical fluid twice；
(2) medicinal material of immersion is evaporated, is ground into medicinal powder；
(3) it being mixed with lactose according to the mass ratio of 1:1.3~1.7 according to medicinal powder, adds ethanol wet agent, ethanol consumption is 0.35~
0.45ml ethyl alcohol/g mixed powder, it is dry, it is sieved, drug is made in sealing, packaging.The concentration of ethanol wet agent used be 70~
90%。
Embodiment two
Join stilbene kidney tonifying diabetes pill, is made of the raw material of following mass parts ratio: American Ginseng 30~32, pilose antler 5~6, Radix Astragali 50~
54, Radix Rehmanniae 30~32, mantis egg-case 20~22, Radix Ophiopogonis 20~22, pulp of dogwood fruit 20~22, Chinese yam 20~22, the fruit of glossy privet 18~20, it is profound
Ginseng 18~20, radices trichosanthis 18~20, Semen Cuscutae 18~20, Radix Paeoniae Alba 28~30, river connect 9~10, tortoiseshell 18~20, fructus lycii 18~
20。
Preparation method is the same as embodiment one.
Embodiment three
Join stilbene kidney tonifying diabetes pill, is made of the raw material of following mass parts ratio: American Ginseng 28~30, pilose antler 4~5, Radix Astragali 46~
50, Radix Rehmanniae 28~30, mantis egg-case 18~20, Radix Ophiopogonis 18~20, pulp of dogwood fruit 18~20, Chinese yam 18~20, the fruit of glossy privet 20~22, it is profound
Ginseng 20~22, radices trichosanthis 20~22, Semen Cuscutae 20~22, Radix Paeoniae Alba 30~32, river connect 10~11, tortoiseshell 20~22, fructus lycii 20
~22.
Preparation method is the same as embodiment one.
Example IV
Join stilbene kidney tonifying diabetes pill, is made of the raw material of following mass parts ratio: American Ginseng 30g, pilose antler 5g, Radix Astragali 50g, Radix Rehmanniae
30g, mantis egg-case 20g, Radix Ophiopogonis 20g, pulp of dogwood fruit 20g, Chinese yam 20g, fruit of glossy privet 20g, radix scrophulariae 20g, radices trichosanthis 20g, Semen Cuscutae
20g, Radix Paeoniae Alba 30g, river connect 10g, tortoiseshell 20g, fructus lycii 20g；
Preparation process:
(1) by the secondary immersion 1h of above-mentioned medicinal material；It is impregnated for the first time with the 20 times of water measured reflux 1h, collects medical fluid；Second of immersion
It is the dregs of a decoction with the 20 times of water measured reflux 1h, collects medical fluid, merge medical fluid twice；
(2) medicinal material of immersion is evaporated, is ground into medicinal powder；
(3) it is mixed with lactose according to 1:1.5 mass ratio according to medicinal powder, adds ethanol wet agent, ethanol consumption is 0.4ml ethyl alcohol/g
Mixed powder, it is dry, it is sieved, seals, packaging.The concentration of ethanol wet agent used is 80%.Quality after above-mentioned medicinal powder is dry contains
Water rate is 3~5%, i.e., contains 3~5 grams of moisture, i.e. the earth moisture content of drug, the side of the measurement of moisture content in 100 grams dry drugs
Method can also use weight method, tensometer method, electric-resistivity method etc..
Embodiment five
Join stilbene kidney tonifying diabetes pill, after full presciption medicine material adds the water of 20 times of amounts to impregnate 1h, refluxing extraction 1h collects medical fluid, and second will
The dregs of a decoction add 20 times of amount water, and refluxing extraction 1h collects medical fluid, merge medical fluid twice, and concentration is dried, crushed into fine powder, according to medicine
Powder: lactose (1:1.5) is added auxiliary material lactose, then plus 80% ethyl alcohol, ethanol consumption is 0.4ml ethyl alcohol/g mixed powder, is made
Grain；Particle 1000g, every 0.25g is made in 60 DEG C of oven dryings.This product is brown particles, and gas is fragrant, mildly bitter flavor.Particle is dry
Dry, uniform in size, color is consistent.
Embodiment six
Example four or five drug studies: drug of the present invention is converted the water of 5 times of weight, to mouse by ten mouse, half male and half female
Stomach-filling, daily it is early, middle and late three times, each dosage be mice weights 2~10%, continuous experiment 30 days.Close observation after administration
The reaction of mouse, observation 4 hours, once a day later.Mouse is deprived of food but not water 12 hours before being administered.Continue to observe after drug withdrawal
Mouse 30 days, mouse was normal, no abnormal reaction.The experiment further proves that drug of the present invention does not have toxicity.
Clinical trial:
Usage and dosage: one time 15 grams (60), three times a day taking orally, a month course for the treatment of, take quench one's thirst symptom after two weeks can
See and is clearly better.
30 patients, 15 35~60 one full year of life of age of male, 15 35~60 one full year of life of age of women.There is high blood before medical
Pressure 1~2 year, diabetes 5~20 years.BP:140/92mmHg or more, specific gravity of urine 1.040~1.045, glycosylated hemoglobin
10.50, glucose 17.96, tongue is dark red, and tongue fur is few, wiry and rolling pulse.
It is one month oral that above-mentioned sufferer takes present invention ginseng stilbene kidney tonifying diabetes pill.
Further consultation after one month: 14 male patients and the thirsty dry of 13 female patients improve, and continue to take ginseng stilbene kidney tonifying
Diabetes pill one month.
Three examine after spending one month: having saliva raw on 14 male patients and 13 female patient tongues, spirit is good, sleeps, and drinks
Still, characteristic of disease turns for the better by and large food.Continue to take ginseng two courses for the treatment of of stilbene kidney tonifying diabetes pill, recover.2 women clothes of other 1 male
After ginseng three courses for the treatment of of stilbene kidney tonifying diabetes pill, thirsty dry improves, and treats effective.
To sum up, present invention effective percentage 100%, cure rate 90%.
Typical case: patient: Liu Qinglin, male, 55 years old, consultation time on July 20th, 2017.
Main suit: thirsty 1 month, existing burnout out of strength was defecated day row 1 time, and night sleeps bad, do not feel like eating.
Past medical history: hypertension 1 year, diabetes 20 years.BP:144/94mmHg, specific gravity of urine 1.041, glycosylated hemoglobin
10.50, glucose 17.96, tongue is dark red, and tongue fur is few, wiry and rolling pulse.
It is one month oral to give ginseng stilbene kidney tonifying diabetes pill.
The further consultation on the 24th of August in 2017.Two examine: thirsty dry improves, and continues to take ginseng stilbene kidney tonifying diabetes pill.
The further consultation on the 21st of September in 2017.Three examine: having saliva raw on tongue, spirit is good, sleeps, diet is fine.Continue to take ginseng stilbene
Kidney tonifying diabetes pill.
Particle of the present invention extracts, forms optimised process:
1, ratio of briquetting: the weight of particle made of weighed, and ratio of briquetting is calculated as follows:
Ratio of briquetting (%)=practical shaped granule weight/theory answers molding particle weight X100%
2, granularity: pressing and provide under " Chinese Pharmacopoeia " granulometry (one the second method of annex XIE of version in 2010, double sieve methods),
No.1 (10 mesh) sieve is placed on No. five (80 mesh) sieves, and is equipped under No. five sieves and closely sealed to receive instrument.Take above-mentioned preparation
Granule, it is accurately weighed, be placed in No.1 sieve in, cover upper cover；Horizontality sieving is kept, left and right is round-trip, claps when sieving
It makes a call to 3 minutes；Taking cannot be sieved by No.1 and granularity can be calculated as follows by the particle of No. five sieves, accurately weighed weight:
Granularity (%)=(weight is not sieved by No.1+pass through No. five sieve particle weights)/sieve preceding weight X100%.
3, it hydroscopicity: is measured according to " Chinese Pharmacopoeia " aquametry (the one annex IXH of version in 2010), unless otherwise specified
Outside, 6.0% must not be crossed.The glass desicator that bottom fills sodium chloride supersaturated solution is placed into 48h at room temperature, drier reaches
To balance, the relative humidity in drier is 75%.Weighing bottle and particle are respectively dried to constant weight, in the weighing bottle of constant weight
Bottom is put into the particle of thickness about 2mm, and precisely weighed.Above-mentioned weighing bottle is put into drier (weigh the cap opening), it is closed
It places, it is accurately weighed.Moisture percentage is calculated as follows:
Particle weight before hydroscopicity (%)=(particle weight before particle weight-moisture absorption after moisture absorption) X100%/moisture absorption
4, mobility: using fixed funnel method, and simultaneously staggered positions that 3 funnels are connected up and down are fixed on horizontal positioned coordinate
On paper at the height of 1cm, careful can will sieve not falling slowly by No. five uniformly mixed particles of sieve along hopper walls by No.1
Enter in the funnel on most, until the nib contacts to bell mouth of the drug cone formed by nethermost funnel, surveys
Conical base diameter (R) out.Angle of repose is calculated as follows, is measured in parallel 5 times, calculates average value.Angle of repose (a)=arctan(H/
R)
5, melting: shining under " Chinese Pharmacopoeia " (the one annex IC of version in 2010) and provide, 1 bag of (multi-dose of accurately weighed test sample
Packaging takes 10g), water (70 degrees Celsius) 200ml is heated, stirs 5 minutes, observes immediately.Soluble particles should all melt, and allow to have
Slight turbid.
6, the selection of auxiliary material and wetting agent: Chinese medicinal granule often has sucrose, dextrin, starch, lactose etc. with auxiliary material, in conjunction with reference
Document considers that prescription has original powder addition from the simplicity of experiment, so not needing to add excipient, need to add for improvement bitter taste of drug strong
Taste agent lactose cannot select water for wetting agent, medicinal second may be selected as auxiliary material, this compound medicinal ingredient most of soluble in water
Alcohol is wetting agent.It selects ethyl alcohol that can also reduce the granule dry time for wetting agent, and reduces drying temperature.
7, the screening of mixed accessories ratio: the indexs such as integrated survey ratio of briquetting, granularity, hydroscopicity, mobility, melting,
Determine preferred plan, granules of sugar does not add 80% alcohol 0.4ml/g ratio of briquetting best.
8, since extraction gained medicinal powder is placed in air, bonding easy to moisture absorption is agglomerating, and adding appropriate excipient granulation has
Conducive to the dispersion and reduction viscosity, hygroscopicity of Chinese medical extract, this compound bitter taste is heavier, and addition corrigent helps to cover Chinese medicine
Bitter taste, enhancing patient is to the compliance of drug.This experiment is with the ratio of briquetting of particle, granularity, hydroscopicity, mobility, melting
Auxiliary material proportion, concentration of wetting agent and its dosage are more comprehensively investigated, determines particle by single factor exploration for main indicator
Agent preparation process.
Claims (3)
1. joining stilbene kidney tonifying diabetes pill, it is characterised in that: be made of the raw material of following mass parts ratio: American Ginseng 28~32, pilose antler 4
~6, Radix Astragali 46~54, Radix Rehmanniae 28~32, mantis egg-case 18~22, Radix Ophiopogonis 18~22, pulp of dogwood fruit 18~22, Chinese yam 18~22, female
Loyal son 18~22, radix scrophulariae 18~22, radices trichosanthis 18~22, Semen Cuscutae 18~22, Radix Paeoniae Alba 28~32, river connect 9~11, tortoiseshell 18~
22, fructus lycii 18~22；
Preparation process:
(1) above-mentioned medicinal material is impregnated twice；It is impregnated for the first time with 18~22 times of water measured 0.~1.2h of reflux, collects medical fluid；The
Secondary immersion is the dregs of a decoction with 18~22 times of 0.8~1.2h of the water measured reflux；
(2) medicinal material of immersion is evaporated, is ground into medicinal powder；
(3) it being mixed with lactose according to the mass ratio of 1:1.3~1.7 according to medicinal powder, adds ethanol wet agent, ethanol consumption is 0.35~
0.45ml ethyl alcohol/g mixed powder, it is dry, it is sieved, drug is made in sealing, packaging.
2. ginseng stilbene kidney tonifying diabetes pill as described in claim 1, it is characterised in that: be made of the raw material of following mass parts ratio: west
American ginseng 30~32, pilose antler 5~6, Radix Astragali 50~54, Radix Rehmanniae 30~32, mantis egg-case 20~22, Radix Ophiopogonis 20~22, pulp of dogwood fruit 20~
22, Chinese yam 20~22, the fruit of glossy privet 18~20, radix scrophulariae 18~20, radices trichosanthis 18~20, Semen Cuscutae 18~20, Radix Paeoniae Alba 28~30, river
Even 9~10, tortoiseshell 18~20, fructus lycii 18~20.
3. ginseng stilbene kidney tonifying diabetes pill as described in claim 1, it is characterised in that: be made of the raw material of following mass parts ratio: west
American ginseng 28~30, pilose antler 4~5, Radix Astragali 46~50, Radix Rehmanniae 28~30, mantis egg-case 18~20, Radix Ophiopogonis 18~20, pulp of dogwood fruit 18~
20, Chinese yam 18~20, the fruit of glossy privet 20~22, radix scrophulariae 20~22, radices trichosanthis 20~22, Semen Cuscutae 20~22, Radix Paeoniae Alba 30~32, river
Even 10~11, tortoiseshell 20~22, fructus lycii 20~22.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101700354A (en) * | 2009-11-20 | 2010-05-05 | 宁夏千宗宝糖尿病肾病研究所 | Traditional Chinese medicine for treating diabetes |
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2019
- 2019-04-12 CN CN201910295635.1A patent/CN109806334A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700354A (en) * | 2009-11-20 | 2010-05-05 | 宁夏千宗宝糖尿病肾病研究所 | Traditional Chinese medicine for treating diabetes |
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Application publication date: 20190528 |