CN1097990A - 一种治疗股癣的药物 - Google Patents
一种治疗股癣的药物 Download PDFInfo
- Publication number
- CN1097990A CN1097990A CN 94100712 CN94100712A CN1097990A CN 1097990 A CN1097990 A CN 1097990A CN 94100712 CN94100712 CN 94100712 CN 94100712 A CN94100712 A CN 94100712A CN 1097990 A CN1097990 A CN 1097990A
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- CN
- China
- Prior art keywords
- medicine
- tinea cruris
- effect
- caused
- percent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000010618 Tinea cruris Diseases 0.000 title claims abstract description 12
- 239000003814 drug Substances 0.000 title claims abstract description 12
- 229940079593 drug Drugs 0.000 title description 4
- ABBQHOQBGMUPJH-UHFFFAOYSA-M Sodium salicylate Chemical compound [Na+].OC1=CC=CC=C1C([O-])=O ABBQHOQBGMUPJH-UHFFFAOYSA-M 0.000 claims abstract description 4
- 239000007864 aqueous solution Substances 0.000 claims abstract description 4
- CEYWPVCZMDVGLZ-BEPFRFAYSA-N (2r,3r,5z)-5-ethylidene-2-hydroxy-2,3-dimethylhexanedioic acid Chemical compound C\C=C(C(O)=O)\C[C@@H](C)[C@@](C)(O)C(O)=O CEYWPVCZMDVGLZ-BEPFRFAYSA-N 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 229930189603 alysine Natural products 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 12
- 239000007788 liquid Substances 0.000 abstract description 3
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract description 2
- 230000036783 anaphylactic response Effects 0.000 abstract description 2
- 208000003455 anaphylaxis Diseases 0.000 abstract description 2
- 229960004025 sodium salicylate Drugs 0.000 abstract description 2
- PUKLDDOGISCFCP-JSQCKWNTSA-N 21-Deoxycortisone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2=O PUKLDDOGISCFCP-JSQCKWNTSA-N 0.000 abstract 1
- FCYKAQOGGFGCMD-UHFFFAOYSA-N Fulvic acid Natural products O1C2=CC(O)=C(O)C(C(O)=O)=C2C(=O)C2=C1CC(C)(O)OC2 FCYKAQOGGFGCMD-UHFFFAOYSA-N 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 241000223229 Trichophyton rubrum Species 0.000 abstract 1
- 229940095100 fulvic acid Drugs 0.000 abstract 1
- 239000002509 fulvic acid Substances 0.000 abstract 1
- 244000053095 fungal pathogen Species 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 231100000241 scar Toxicity 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000002674 ointment Substances 0.000 description 3
- 108010077913 Triamcinolone Acetonide Drug Combination Nystatin Neomycin Sulfate Gramicidin Proteins 0.000 description 2
- 241000223238 Trichophyton Species 0.000 description 2
- 210000000589 cicatrix Anatomy 0.000 description 2
- 229960004022 clotrimazole Drugs 0.000 description 2
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003429 antifungal agent Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
本发明涉及一种治疗股癣的药物，它是一种含灰
黄霉酸50—60％的水溶液，外加水扬酸钠0.5—过
2g/100ml。该药液安全、无毒副作用，无过敏反应，
无腐蚀性，止痒效果显著。对于致病真菌、红色毛癣
菌等引起的股癣有特效。用药后，不留瘢痕，不再复
发。经临床对照观察，显效率为14％，有效率为
86％。
Description
本发明属于含有机物配料之医药制剂。
股癣是一种顽固性疾病，是由致病真菌、红色毛癣菌等引起，其特点是，发病部位明确，反复发病，病程时间长，最长有20年之久，症状、体征表现以夏季为重，目前，治疗这种疾病并无特效药。在多种抗真菌药物中，克霉唑软膏及复方康纳乐霜软膏剂型效果最好，但有效率也仅达50%，且易复发。
本发明的目的是提供一种治疗股癣的特效药物，其有效率较高，价格便宜，用药后，无瘢痕，不再复发，该药无毒付作用及过敏反应。
本发明是这样实现的：它是一种含灰黄霉酸50-60%的水溶液，外加水扬酸钠0.5-2g/100ml。含有氨基酸等有益成分，不影响其疗效。
经有关资料记载，水杨酸具有杀灭寄生于皮肤深部真菌及溶解皮肤角质的作用，但单独使用它时效果很差;灰黄霉酸是一种生物制剂，据报道，它并没有治疗股癣的作用。经临床试验，将水杨酸钠和灰黄霉酸水溶液按一定比例配在一起，发现治疗股癣的效果相当明显，远远优于到目前为止所知的各种治疗股癣的药物。
临床及实验证明，该药液无毒付作用，无过敏反应，无腐蚀性，止痒效果显著，使用安全，对于致病真菌、红色毛癣菌等引起的股癣有特效，用药后，不留瘢痕，不复发。
以下是本发明的实施例：
上述几种浓度均可在临术中应用。一般使用方法是外涂于患处，一日2-3次。
以下是某医院临床治疗57例股癣患者对照观察表：
说明：治疗组用本药液，对照组使用克霉唑软膏及复方康纳乐霜。
Claims (1)
1、一种治疗股癣的药物，其特征是一种含灰黄霉酸50-60%的水溶液，外加水扬酸钠0.5-2g/100ml。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94100712 CN1097990A (zh) | 1994-01-29 | 1994-01-29 | 一种治疗股癣的药物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94100712 CN1097990A (zh) | 1994-01-29 | 1994-01-29 | 一种治疗股癣的药物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1097990A true CN1097990A (zh) | 1995-02-01 |
Family
ID=5029792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 94100712 Pending CN1097990A (zh) | 1994-01-29 | 1994-01-29 | 一种治疗股癣的药物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1097990A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000019999A1 (en) * | 1998-10-08 | 2000-04-13 | Enerkom (Proprietary) Limited | Fulvic acid and its use in the treatment of various conditions |
-
1994
- 1994-01-29 CN CN 94100712 patent/CN1097990A/zh active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000019999A1 (en) * | 1998-10-08 | 2000-04-13 | Enerkom (Proprietary) Limited | Fulvic acid and its use in the treatment of various conditions |
| JP2002526407A (ja) * | 1998-10-08 | 2002-08-20 | エナーコム（プロプライエタリー）・リミテッド | フルボ酸、および種々の状態の処置におけるその使用 |
| EP1698333A1 (en) * | 1998-10-08 | 2006-09-06 | Pfeinsmith Limited | Fulvic acid and its use in the treatment of viral infections |
| EP1700599A1 (en) * | 1998-10-08 | 2006-09-13 | Pfeinsmith Limited | Fulvic acid and its use in the treatment of candida infections |
| EP1700600A1 (en) * | 1998-10-08 | 2006-09-13 | Pfeinsmith Limited | Fulvic acid and its use in the treatment of inflammation |
| JP4700808B2 (ja) * | 1998-10-08 | 2011-06-15 | プフェインスミス・リミテッド | フルボ酸、および種々の状態の処置におけるその使用 |
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