CN109776668B - Concussion purifier for recombinant nerve growth factor - Google Patents
Concussion purifier for recombinant nerve growth factor Download PDFInfo
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- CN109776668B CN109776668B CN201910177774.4A CN201910177774A CN109776668B CN 109776668 B CN109776668 B CN 109776668B CN 201910177774 A CN201910177774 A CN 201910177774A CN 109776668 B CN109776668 B CN 109776668B
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- 108010025020 Nerve Growth Factor Proteins 0.000 title claims abstract description 16
- 102000015336 Nerve Growth Factor Human genes 0.000 title claims description 11
- 229940053128 nerve growth factor Drugs 0.000 title claims description 11
- 230000009514 concussion Effects 0.000 title claims description 4
- 230000007246 mechanism Effects 0.000 claims abstract description 66
- 238000000746 purification Methods 0.000 claims abstract description 54
- 230000010355 oscillation Effects 0.000 claims abstract description 43
- 239000000969 carrier Substances 0.000 claims description 6
- 230000008521 reorganization Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 15
- 230000033001 locomotion Effects 0.000 abstract description 9
- 102000007072 Nerve Growth Factors Human genes 0.000 abstract description 5
- 230000001276 controlling effect Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 230000012010 growth Effects 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- 238000007792 addition Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000005709 nerve cell growth Effects 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 210000002856 peripheral neuron Anatomy 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
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- Zoology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Transmission Devices (AREA)
Abstract
The invention relates to the technical field of medical appliances, in particular to an oscillation purifier for recombining nerve growth factors, which can realize the up-and-down oscillation of an extracting solution in a purifying tube by controlling an oscillation driving mechanism, and a rotation control mechanism can drive the oscillation driving mechanism and the purifying tube in a rotation driving piece to perform circular motion, so that the annular oscillation and the up-and-down oscillation of the purifying tube can be applied to the purifying tube to form the oscillation purifying effect; the device has replaced artifical hand and has rocked the purification pipe, avoids appearing shaking the not good phenomenon of effect and takes place, very big work degree of difficulty that has alleviateed medical staff. Lower extreme sliding connection of support on the base, the drive shaft rotates to be connected on the support, the lower extreme and the base of drive shaft are connected, vibrate actuating mechanism sliding connection on the base, rotary driving piece fixed connection is in the upper end of vibrating actuating mechanism, vibrate actuating mechanism and rotary driving piece and all connect in the drive shaft.
Description
Technical Field
The invention relates to the technical field of medical appliances, in particular to a shock purifier for a recombinant nerve growth factor.
Background
The nerve growth factor is a nerve cell growth regulating factor with double biological functions of nourishing, protecting nerves and promoting protrusion growth in nerve growth factors, and has important regulation and control functions on development, differentiation, growth, regeneration and expression of functional characteristics of central and peripheral neurons. In the experiment, the extracting solution in the purifying tube needs to be vibrated in the nucleic acid extracting process, and if the vibration is not timely or the vibration effect is not good, a series of negative influences can be generated, so that the design of the vibrating device is very necessary.
Disclosure of Invention
The invention aims to provide a vibration purifier for recombining nerve growth factors, which has the advantages that the device can realize up-and-down vibration of extracting solution in a purifying tube by controlling a vibration driving mechanism, and a rotation control mechanism can drive the vibration driving mechanism and the purifying tube in a rotation driving piece to perform circular motion, so that the circular vibration of the purifying tube and the bumping effect of the up-and-down vibration can be applied to the purifying tube to form the vibration purifying effect; the device has replaced artifical hand and has rocked the purification pipe, avoids appearing shaking the not good phenomenon of effect and takes place, very big work degree of difficulty that has alleviateed medical staff.
The invention relates to the technical field of medical appliances, in particular to an oscillation purifier for recombining nerve growth factors, which comprises a base, a bracket, a driving shaft, an oscillation driving mechanism, a rotary driving piece and a rotary control mechanism, wherein the device can realize up-and-down oscillation of an extracting solution in a purifying tube by controlling the oscillation driving mechanism, and the rotary control mechanism can drive the oscillation driving mechanism and the purifying tube in the rotary driving piece to perform circular motion, so that the circular oscillation of the purifying tube and the bumping effect of the up-and-down oscillation can be applied to the purifying tube to form an oscillation purifying effect; the device has replaced artifical hand and has rocked the purification pipe, avoids appearing shaking the not good phenomenon of effect and takes place, very big work degree of difficulty that has alleviateed medical staff.
Lower extreme sliding connection of support on the base, the drive shaft rotates to be connected on the support, the lower extreme and the base of drive shaft are connected, vibrate actuating mechanism sliding connection on the base, rotary driving piece fixed connection is in the upper end of vibrating actuating mechanism, vibrate actuating mechanism and rotary driving piece and all connect in the drive shaft, rotary driving piece's both ends joint is at the both ends of support, rotary control mechanism sets up the upper end at rotary driving piece.
The base on be provided with race and rack I, the upper end fixedly connected with rack I of base is provided with two races on the base.
The support comprises a bottom plate, door-shaped frames, vertical sliding grooves, inserting grooves, folding rods, shaft seat plates, a motor frame, a driving shaft, a gear I, a driving bevel gear, a short shaft, an incomplete gear, a driven bevel gear, pulley columns and pulleys, wherein the two door-shaped frames are fixedly connected to two ends of the bottom plate, the front and back ends of the lower ends of the two door-shaped frames are respectively provided with the vertical sliding grooves, the upper ends of the two door-shaped frames are respectively provided with the inserting grooves, the shaft seat plates are fixedly connected to the upper ends of the two door-shaped frames through the folding rods, the motor frame is fixedly connected to the folding rods, the driving shaft is rotatably connected to the right end of the bottom plate, the gear I is fixedly connected to the lower end of the driving shaft, the gear I is meshed with a rack I, the driving bevel gear is fixedly connected to the upper end of the driving shaft, the short shaft is rotatably connected to the door-shaped frames positioned at the right ends of the short shaft, the middle end of the short shaft is fixedly connected with the incomplete gear, and the rear end of the short shaft is fixedly connected with the driven bevel gear, driven bevel gear and the meshing of drive bevel gear, four angles departments of the lower extreme of bottom plate all are connected with the pulley through the pulley post rotation, and two pulleys at front and back both ends are sliding connection respectively in two race.
The drive shaft on be provided with motor, rectangular channel, spacing ring and gear II, drive shaft fixed connection is on the output shaft of motor, motor fixed connection is on the motor frame, the lower extreme of drive shaft rotates and connects on the bottom plate, the lower extreme fixedly connected with gear II of drive shaft, gear II and I meshing of rack, the upper end of drive shaft rotates and connects on the bedplate of axle, the upper end of drive shaft is provided with the rectangular channel, the rectangular channel is located the below of bedplate of axle, two spacing rings of middle-end fixedly connected with of drive shaft.
The vibration driving mechanism comprises T-shaped sliding blocks, circular grooves, reciprocating discs, circular rings, push rods, a purifying tube chassis, purifying tube bottom slots, push rod sliding seats and a rack II, wherein the two T-shaped sliding blocks are respectively connected on vertical sliding grooves at the left end and the right end in a sliding manner, the inner sides of the two T-shaped sliding blocks are respectively provided with the circular grooves, the outer ring of the reciprocating disc is fixedly connected with the circular rings, the reciprocating discs are connected in the two circular grooves in a sliding manner through the circular rings, a plurality of push rods are distributed at the upper end of the reciprocating disc along the circumference, a plurality of purifying tube bottom slots are distributed on the purifying tube chassis along the circumference, a plurality of push rod sliding seats are distributed at the lower end of the purifying tube chassis along the circumference, the plurality of push rod sliding seats are respectively communicated with the plurality of purifying tube bottom slots, the plurality of push rods are respectively connected at the lower ends of the push rod sliding seats in a sliding manner, semicircular grooves are formed at the upper ends of the push rods, springs are sleeved on the plurality of the push rod sliding seats, and are positioned between the purifying tube chassis and the reciprocating disc, and a rack II is fixedly connected to the T-shaped sliding block at the right end, the incomplete gear is meshed with the rack II, the reciprocating disc and the purification tube chassis are in clearance fit with the driving shaft, and the two limiting rings are respectively positioned at the upper end and the lower end of the purification tube chassis.
The rotary driving part comprises a driving turntable, a purification tube limiting groove, a sliding groove seat, sliding grooves, plug-in pieces, hinging rods, a round rod groove, a gear carrier, a gear III and a T-shaped sliding rail, the driving turntable is in clearance fit with a driving shaft, a plurality of purification tube limiting grooves are distributed on the driving turntable along the circumference, the purification tube limiting grooves are all coaxial with a plurality of purification tube bottom inserting grooves, the left end and the right end of the lower end of the driving turntable are symmetrically and fixedly connected with two sliding groove seats, the lower ends of the two sliding groove seats are fixedly connected with the two ends of a purification tube chassis, the outer ends of the two sliding groove seats are respectively provided with the sliding grooves, the two plug-in pieces are respectively connected in the two sliding grooves in a sliding manner, a spring is fixedly connected between the plug-in pieces and the sliding grooves, the outer ends of the two plug-in pieces are respectively inserted in the two inserting grooves in a clearance manner, the middle ends of the two hinging rods are symmetrically hinged on the driving turntable, the outer ends of the two hinging rods are respectively provided with the round rod grooves, the two plug-in a sliding manner, the inner of two articulated rods all takes on rotary control mechanism, and gear III rotates to be connected on two carriers, and two carrier fixed connection are on the drive carousel, and T type slide rail fixed connection is in drive carousel front end intermediate position.
The plug-in components on be provided with slide, picture peg and round bar, slide sliding connection is in the spout, the lower extreme fixedly connected with picture peg of slide, the picture peg clearance is pegged graft in the slot, round bar fixed connection is in the upper end of slide, round bar sliding connection is in the round bar inslot.
The rotary control mechanism include T type groove slide, T type groove, the push-and-pull rod, rack III, inserted bar slide and slip inserted bar, the lower extreme of T type groove slide is provided with T type groove, T type groove slide passes through T type groove sliding connection on T type slide rail, be provided with fastening screw on the T type groove slide, fastening screw pushes up on T type slide rail, the rear end fixedly connected with push-and-pull rod of T type groove slide, the both ends at the push-and-pull rod are taken to the front end of two articulated links, the front end fixedly connected with rack III of push-and-pull rod, rack III and gear III's lower extreme meshing, the upper end fixedly connected with inserted bar slide of T type groove slide, slip inserted bar sliding connection is on the inserted bar slide, slip inserted bar and gear III's upper end meshing.
The shock purifier for the recombinant nerve growth factor has the beneficial effects that:
according to the oscillation purifier for the recombinant nerve growth factor, disclosed by the invention, the device can realize up-and-down oscillation of the extracting solution in the purifying tube by controlling the oscillation driving mechanism, and the rotation control mechanism can drive the oscillation driving mechanism and the purifying tube in the rotation driving piece to perform circular motion, so that the bumping effect of the annular shaking and the up-and-down oscillation of the purifying tube can be applied to the purifying tube to form the oscillation purifying effect; the device has replaced artifical hand and has rocked the purification pipe, avoids appearing shaking the not good phenomenon of effect and takes place, very big work degree of difficulty that has alleviateed medical staff.
Drawings
The invention is described in further detail below with reference to the accompanying drawings and specific embodiments.
FIG. 1 is a schematic structural diagram of an oscillation purifier for recombinant nerve growth factor according to the present invention;
FIG. 2 is a schematic structural diagram of a base;
FIG. 3 is a schematic structural view of a stent;
FIG. 4 is a schematic view of the construction of the drive shaft;
FIG. 5 is a schematic structural diagram of the oscillating driving mechanism;
FIG. 6 is a schematic structural view of the rotary driving member;
FIG. 7 is a schematic view of the structure of the insert;
fig. 8 is a schematic structural view of the rotation control mechanism.
In the figure: a base 1; 1-1 of wheel groove; a rack I1-2; a bracket 2; a bottom plate 2-1; a door-shaped frame 2-2; 2-3 of vertical chutes; 2-4 of a slot; 2-5 of folding rod; 2-6 parts of a bearing plate; 2-7 of a motor frame; 2-8 of a driving shaft; 2-9 parts of a gear I; 2-10 parts of a driving bevel gear; short axis 2-11; 2-12 parts of incomplete gear; driven bevel gears 2-13; pulley columns 2-14; 2-15 parts of a pulley; a drive shaft 3; a motor 3-1; 3-2 of rectangular groove; 3-3 of a limiting ring; 3-4 parts of a gear II; an oscillation driving mechanism 4; a T-shaped sliding block 4-1; a circular groove 4-2; 4-3 of a reciprocating disc; 4-4 parts of a circular ring; 4-5 of a push rod; 4-6 parts of a purification tube chassis; 4-7 of purification tube bottom slot; 4-8 parts of a push rod sliding seat; 4-9 of a rack; a rotary drive member 5; driving the rotating disc 5-1; 5-2 parts of a purification tube limiting groove; 5-3 of a sliding groove seat; 5-4 of a chute; 5-5 of an insert; 5-5-1 of a sliding plate; 5-5-2 of an inserting plate; 5-5-3 parts of round rod; hinge rods 5-6; 5-7 parts of a round rod groove; 5-8 parts of a gear rack; 5-9 parts of gear III; 5-10 parts of T-shaped slide rail; a rotation control mechanism 6; a T-shaped groove sliding seat 6-1; 6-2 of a T-shaped groove; 6-3 of a push-pull rod; 6-4 of a rack; 6-5 of a plug-in rod sliding seat; and 6-6 of a sliding inserting strip.
Detailed Description
The first embodiment is as follows:
the embodiment is described below with reference to fig. 1 to 8, and the invention relates to the technical field of medical appliances, in particular to an oscillation purifier for recombinant nerve growth factors, which comprises a base 1, a bracket 2, a driving shaft 3, an oscillation driving mechanism 4, a rotary driving member 5 and a rotary control mechanism 6, wherein the device can realize up-and-down oscillation of an extracting solution in a purifying tube by controlling the oscillation driving mechanism 4, and the rotary control mechanism 6 can drive the oscillation driving mechanism 4 and the purifying tube in the rotary driving member 5 to perform circular motion, so that the circular oscillation and the up-and-down oscillation of the purifying tube can exert the bumping effect on the purifying tube to form the oscillation purifying effect; the device has replaced artifical hand and has rocked the purification pipe, avoids appearing shaking the not good phenomenon of effect and takes place, very big work degree of difficulty that has alleviateed medical staff.
The lower end of the support 2 is connected to the base 1 in a sliding mode, the driving shaft 3 is connected to the support 2 in a rotating mode, the lower end of the driving shaft 3 is connected with the base 1, the oscillation driving mechanism 4 is connected to the base 1 in a sliding mode, the rotary driving piece 5 is fixedly connected to the upper end of the oscillation driving mechanism 4, the oscillation driving mechanism 4 and the rotary driving piece 5 are both connected to the driving shaft 3, two ends of the rotary driving piece 5 are connected to two ends of the support 2 in a clamping mode, and the rotary control mechanism 6 is arranged at the upper end of the rotary driving piece 5; when using, insert the middle-end of a plurality of purification pipes in rotary driving piece 5, the lower extreme of a plurality of purification pipes inserts the upper end of vibrating actuating mechanism 4, pass through wire connection power and start with drive shaft 3, drive shaft 3 drives support 2 and slides from side to side on base 1, the lower extreme of vibrating actuating mechanism 4 can drive a plurality of purification pipes and vibrate from top to bottom, both ends and the separation of frame base 1 back through 6 control rotary driving piece 5 of rotary control mechanism, drive shaft 3 can drive rotary driving piece 5 and vibrate actuating mechanism 4 and rotate, thereby it is the circular motion to drive the purification pipe.
The base 1 is provided with a wheel groove 1-1 and a rack I1-2, the upper end of the base 1 is fixedly connected with the rack I1-2, and the base 1 is provided with two wheel grooves 1-1.
The support 2 comprises a bottom plate 2-1, door-shaped frames 2-2, vertical sliding grooves 2-3, slots 2-4, folding rods 2-5, a shaft seat plate 2-6, a motor frame 2-7, a driving shaft 2-8, gears I2-9, driving bevel gears 2-10, short shafts 2-11, incomplete gears 2-12, driven bevel gears 2-13, pulley columns 2-14 and pulleys 2-15, wherein the two door-shaped frames 2-2 are fixedly connected to two ends of the bottom plate 2-1, the front and rear ends of the lower ends of the two door-shaped frames 2-2 are respectively provided with the vertical sliding grooves 2-3, the upper ends of the two door-shaped frames 2-2 are respectively provided with the slots 2-4, the shaft seat plate 2-6 is fixedly connected to the upper ends of the two door-shaped frames 2-2 through the folding rods 2-5, a motor frame 2-7 is fixedly connected to a folding rod 2-5, a driving shaft 2-8 is rotatably connected to the right end of a bottom plate 2-1, a gear I2-9 is fixedly connected to the lower end of the driving shaft 2-8, the gear I2-9 is meshed with a rack I1-2, a driving bevel gear 2-10 is fixedly connected to the upper end of the driving shaft 2-8, a short shaft 2-11 is rotatably connected to a door-shaped frame 2-2 positioned at the right end, the middle end of the short shaft 2-11 is fixedly connected with an incomplete gear 2-12, the rear end of the short shaft 2-11 is fixedly connected with a driven bevel gear 2-13, the driven bevel gear 2-13 is meshed with the driving bevel gear 2-10, and pulleys 2-15 are rotatably connected at four corners of the lower end of the bottom plate 2-1 through pulley columns 2-14, two pulleys 2-15 at the front end and the rear end are respectively connected in the two pulley grooves 1-1 in a sliding manner; when the bevel gear transmission mechanism is used, the pulleys 2-15 can slide left and right in the pulley groove 1-1 and rotate simultaneously, the pulleys 2-15 play a role in reducing sliding friction force, the gears I2-9 are meshed with the racks I1-2 to drive the gears I2-9, the driving shaft 2-8 and the driving bevel gear 2-10 to rotate, and the driving bevel gear 2-10 drives the incomplete gear 2-12 and the driven bevel gear 2-13 to rotate.
The driving shaft 3 is provided with a motor 3-1, a rectangular groove 3-2, a limiting ring 3-3 and a gear II 3-4, the driving shaft 3 is fixedly connected to an output shaft of the motor 3-1, the motor 3-1 is fixedly connected to a motor frame 2-7, the lower end of the driving shaft 3 is rotatably connected to a bottom plate 2-1, the lower end of the driving shaft 3 is fixedly connected with the gear II 3-4, the gear II 3-4 is meshed with a rack I1-2, the upper end of the driving shaft 3 is rotatably connected to a shaft seat plate 2-6, the upper end of the driving shaft 3 is provided with the rectangular groove 3-2, the rectangular groove 3-2 is positioned below the shaft seat plate 2-6, and the middle end of the driving shaft 3 is fixedly connected with the two limiting rings 3-3; when the automatic sliding type base is used, the motor 3-1 is connected with a power supply through a lead and started, the motor 3-1 drives the driving shaft 3 to rotate, the driving shaft 3 drives the gear II 3-4 to rotate, and the gear II 3-4 drives the bottom plate 2-1, the pulley column 2-14 and the pulley 2-15 to slide left and right on the base 1 through meshing with the rack I1-2.
The vibration driving mechanism 4 comprises T-shaped sliding blocks 4-1, circular grooves 4-2, reciprocating discs 4-3, circular rings 4-4, push rods 4-5, a purification tube base disc 4-6, purification tube bottom slots 4-7, push rod sliding seats 4-8 and racks II 4-9, the two T-shaped sliding blocks 4-1 are respectively connected to the vertical sliding grooves 2-3 at the left end and the right end in a sliding manner, the inner sides of the two T-shaped sliding blocks 4-1 are respectively provided with the circular grooves 4-2, the outer ring of the reciprocating disc 4-3 is fixedly connected with the circular rings 4-4, the reciprocating disc 4-3 is connected in the two circular grooves 4-2 in a sliding manner through the circular rings 4-4, the upper end of the reciprocating disc 4-3 is circumferentially distributed with the push rods 4-5, the purification tube base disc 4-6 is circumferentially distributed with the purification tube bottom slots 4-7, a plurality of push rod sliding seats 4-8 are distributed at the lower end of a purification tube chassis 4-6 along the circumference, the push rod sliding seats 4-8 are all communicated with a plurality of purification tube bottom slots 4-7, a plurality of push rods 4-5 are respectively connected at the lower ends of the push rod sliding seats 4-8 in a sliding manner, semicircular grooves are formed in the upper ends of the push rods 4-5, springs are sleeved on the push rod sliding seats 4-8 and are positioned between the purification tube chassis 4-6 and a reciprocating disc 4-3, a rack II 4-9 is fixedly connected to a T-shaped sliding block 4-1 at the right end, an incomplete gear 2-12 is meshed with the rack II 4-9, the reciprocating disc 4-3 and the purification tube chassis 4-6 are in clearance fit with a driving shaft 3, and two limiting rings 3-3 are respectively positioned at the upper end and the lower end of the purification tube chassis 4-6; when the device is used, the bottom of the purification tube is pressed against a semicircular groove at the upper end of a push rod 4-5, an incomplete gear 2-12 rotates to drive a rack II 4-9 to move up and down, the incomplete gear 2-12 drives two T-shaped sliding blocks 4-1, a reciprocating disc 4-3 and a circular ring 4-4 to slide up and down, the reciprocating disc 4-3 drives a plurality of push rods 4-5 to slide up and down in a plurality of push rod sliding seats 4-8, and the push rods 4-5 drive the purification tube in a purification tube bottom slot 4-7 to vibrate up and down; when the incomplete gear 2-12 is disengaged from the incomplete gear 2-12, the spring enables the reciprocating disc 4-3 to reset; the reciprocating disk 4-3 can rotate on the two T-shaped sliders 4-1 through the circular ring 4-4.
The rotary driving piece 5 comprises a driving turntable 5-1, purification tube limiting grooves 5-2, sliding groove seats 5-3, sliding grooves 5-4, plug-in pieces 5-5, a hinge rod 5-6, a round rod groove 5-7, a gear carrier 5-8, a gear III 5-9 and T-shaped sliding rails 5-10, the driving turntable 5-1 is in clearance fit with the driving shaft 2, a plurality of purification tube limiting grooves 5-2 are distributed on the driving turntable 5-1 along the circumference, a plurality of purification tube limiting grooves 5-2 are all coaxial with a plurality of purification tube bottom slots 4-7, the left end and the right end of the lower end of the driving turntable 5-1 are symmetrically and fixedly connected with two sliding groove seats 5-3, the lower ends of the two sliding groove seats 5-3 are fixedly connected with the two ends of the purification tube bottom slots 4-6, the outer ends of the two sliding groove seats 5-3 are provided with the sliding grooves 5-4, the two plug-in components 5-5 are respectively connected in the two sliding chutes 5-4 in a sliding manner, springs are fixedly connected between the plug-in components 5-5 and the sliding chutes 5-4, the outer ends of the two plug-in components 5-5 are respectively inserted in the two inserting grooves 2-4 in a clearance manner, the middle ends of the two hinge rods 5-6 are symmetrically hinged on the driving turntable 5-1, the outer ends of the two hinge rods 5-6 are respectively provided with a round rod groove 5-7, the two round rod grooves 5-7 are respectively connected on the two plug-in components 5-5 in a sliding manner, the inner ends of the two hinge rods 5-6 are respectively lapped on the rotation control mechanism 6, the gears III 5-9 are rotationally connected on the two gear carriers 5-8, the two gear carriers 5-8 are fixedly connected on the driving turntable 5-1, and the T-shaped sliding rails 5-10 are fixedly connected at the middle position of the front end of the driving turntable 5-1; when the device is used, the rotating control mechanism 6 slides forwards to drive the two hinge rods 5-6 to rotate around the hinge joint, the two hinge rods 5-6 drive the two plug-in units 5-5 to move towards each other at the same time, the two plug-in units 5-5 are separated from the two slots 2-4, the rotating control mechanism 6 slides forwards to drive the gears III 5-9 to rotate, the upper end of the rotating control mechanism 6 is inserted into the rectangular slots 3-2 at the same time, and the driving shaft 3 can drive the driving turntable 5-1 and the oscillation driving mechanism 4 to rotate while rotating, so that the purifying tube is driven to do circular motion; the spring between the plug-in 5-5 and the sliding groove 5-4 gives the two plug-in 5-5 outward thrust, so that the two plug-in 5-5 is always positioned at the outer end of the driving turntable 5-1 when not being subjected to other forces.
The plug-in components 5-5 are provided with sliding plates 5-5-1, plug boards 5-5-2 and round rods 5-5-3, the sliding plates 5-5-1 are connected in the sliding grooves 5-4 in a sliding mode, the lower ends of the sliding plates 5-5-1 are fixedly connected with the plug boards 5-5-2, the plug boards 5-5-2 are inserted in the inserting grooves 2-4 in a clearance mode, the round rods 5-5-3 are fixedly connected at the upper ends of the sliding plates 5-5-1, and the round rods 5-5-3 are connected in the round rod grooves 5-7 in a sliding mode.
The rotation control mechanism 6 comprises a T-shaped groove sliding seat 6-1, a T-shaped groove 6-2, a push-pull rod 6-3, a rack III 6-4, an inserted rod sliding seat 6-5 and a sliding inserted bar 6-6, wherein the lower end of the T-shaped groove sliding seat 6-1 is provided with the T-shaped groove 6-2, the T-shaped groove sliding seat 6-1 is connected to a T-shaped sliding rail 5-10 in a sliding mode through the T-shaped groove 6-2, a fastening screw is arranged on the T-shaped groove sliding seat 6-1 and abuts against the T-shaped sliding rail 5-10, the rear end of the T-shaped groove sliding seat 6-1 is fixedly connected with the push-pull rod 6-3, the front ends of two hinged rods 5-6 are lapped at the two ends of the push-pull rod 6-3, the front end of the push-pull rod 6-3 is fixedly connected with the rack III 6-4, and the rack III 6-4 is meshed with the lower end of a gear III-9, the upper end of the T-shaped groove sliding seat 6-1 is fixedly connected with an inserted bar sliding seat 6-5, a sliding inserted bar 6-6 is connected to the inserted bar sliding seat 6-5 in a sliding mode, and the sliding inserted bar 6-6 is meshed with the upper end of a gear III 5-9; when the T-shaped groove sliding seat is used, the T-shaped groove sliding seat 6-1 slides back and forth on the T-shaped sliding rail 5-10, the fastening screws can fix the position of the T-shaped groove sliding seat 6-1, the push-pull rod 6-3 slides back and forth to drive the two hinge rods 5-6 to rotate simultaneously, the T-shaped groove sliding seat 6-1 drives the rack III 6-4 to slide back and forth, the rack III 6-4 drives the gear III 5-9 to rotate, the gear III 5-9 drives the sliding insert 6-6 to slide back and forth, the sliding insert 6-6 is inserted into the rectangular groove 3-2 when sliding forward, and the driving shaft 3 drives the rotary driving piece 5 to rotate through the sliding insert 6-6 when rotating.
The working principle of the oscillation purifier for the recombinant nerve growth factor comprises the following steps: when the device is used, the middle ends of a plurality of purifying tubes are inserted into the rotary driving piece 5, the lower ends of the purifying tubes are inserted into the upper end of the oscillation driving mechanism 4, the driving shaft 3 is connected with a power supply through a wire and is started, the driving shaft 3 drives the support 2 to slide left and right on the base 1, the lower end of the oscillation driving mechanism 4 can drive the purifying tubes to oscillate up and down, after the two ends of the rotary driving piece 5 are controlled by the rotary control mechanism 6 to be separated from the rack base 1, the driving shaft 3 can drive the rotary driving piece 5 and the oscillation driving mechanism 4 to rotate, and therefore the purifying tubes are driven to do circular motion; the pulleys 2-15 can slide left and right in the pulley groove 1-1 and rotate at the same time, the pulleys 2-15 play a role in reducing sliding friction force, the gears I2-9 are meshed with the racks I1-2 to drive the gears I2-9, the driving shafts 2-8 and the driving bevel gears 2-10 to rotate, and the driving bevel gears 2-10 drive the incomplete gears 2-12 and the driven bevel gears 2-13 to rotate; the motor 3-1 is connected with a power supply through a lead and started, the motor 3-1 drives the driving shaft 3 to rotate, the driving shaft 3 drives the gear II 3-4 to rotate, and the gear II 3-4 is meshed with the rack I1-2 to drive the bottom plate 2-1, the pulley columns 2-14 and the pulleys 2-15 to slide left and right on the base 1; the bottom of the purification tube is propped against a semicircular groove at the upper end of a push rod 4-5, an incomplete gear 2-12 rotates to drive a rack II 4-9 to move up and down, the incomplete gear 2-12 drives two T-shaped slide blocks 4-1, a reciprocating disc 4-3 and a circular ring 4-4 to slide up and down, the reciprocating disc 4-3 drives a plurality of push rods 4-5 to slide up and down in a plurality of push rod slide seats 4-8, and the push rods 4-5 drive the purification tube in a purification tube bottom slot 4-7 to vibrate up and down; when the incomplete gear 2-12 is disengaged from the incomplete gear 2-12, the spring enables the reciprocating disc 4-3 to reset; the reciprocating disk 4-3 can rotate on the two T-shaped sliding blocks 4-1 through the circular ring 4-4; the rotary control mechanism 6 slides forwards to drive the two hinge rods 5-6 to rotate around the hinge joints, the two hinge rods 5-6 drive the two plug-in units 5-5 to move towards each other at the same time, the two plug-in units 5-5 are separated from the two slots 2-4, the rotary control mechanism 6 slides forwards to drive the gears III 5-9 to rotate, the upper end of the rotary control mechanism 6 is inserted into the rectangular slot 3-2 at the same time, and the drive shaft 3 can drive the drive turntable 5-1 and the oscillation drive mechanism 4 to rotate while rotating, so that the purification tube is driven to do circular motion; the T-shaped groove sliding seat 6-1 slides back and forth on the T-shaped sliding rail 5-10, the position of the T-shaped groove sliding seat 6-1 can be fixed by a fastening screw, the push-pull rod 6-3 slides back and forth to drive the two hinge rods 5-6 to rotate simultaneously, the T-shaped groove sliding seat 6-1 drives the rack III 6-4 to slide back and forth, the rack III 6-4 drives the gear III 5-9 to rotate, the gear III 5-9 drives the sliding insert 6-6 to slide back and forth, the sliding insert 6-6 is inserted into the rectangular groove 3-2 when sliding forward, and the rotary driving piece 5 is driven to rotate by the sliding insert 6-6 when the driving shaft 3 rotates.
It is to be understood that the above description is not intended to limit the present invention, and the present invention is not limited to the above examples, and that various changes, modifications, additions and substitutions which are within the spirit and scope of the present invention and which may be made by those skilled in the art are also within the scope of the present invention.
Claims (3)
1. The utility model provides a vibration purifier of nerve growth factor of reorganization, includes base (1), support (2), drive shaft (3), vibrates actuating mechanism (4), rotary driving spare (5) and rotation control mechanism (6), its characterized in that: the lower end of the support (2) is connected to the base (1) in a sliding mode, the driving shaft (3) is connected to the support (2) in a rotating mode, the lower end of the driving shaft (3) is connected with the base (1), the oscillation driving mechanism (4) is connected to the base (1) in a sliding mode, the rotary driving piece (5) is fixedly connected to the upper end of the oscillation driving mechanism (4), the oscillation driving mechanism (4) and the rotary driving piece (5) are connected to the driving shaft (3), the two ends of the rotary driving piece (5) are connected to the two ends of the support (2) in a clamping mode, and the rotary control mechanism (6) is arranged at the upper end of the rotary driving piece (5);
the base (1) is provided with a wheel groove (1-1) and a rack I (1-2), the upper end of the base (1) is fixedly connected with the rack I (1-2), and the base (1) is provided with two wheel grooves (1-1);
the support (2) comprises a bottom plate (2-1), door-shaped frames (2-2), vertical sliding grooves (2-3), inserting grooves (2-4), folding rods (2-5), a shaft seat plate (2-6), motor frames (2-7), a driving shaft (2-8), a gear I (2-9), a driving bevel gear (2-10), a short shaft (2-11), an incomplete gear (2-12), driven bevel gears (2-13), pulley columns (2-14) and pulleys (2-15), the two door-shaped frames (2-2) are fixedly connected with two ends of the bottom plate (2-1), the vertical sliding grooves (2-3) are arranged at the front and rear ends of the lower ends of the two door-shaped frames (2-2), the inserting grooves (2-4) are arranged at the upper ends of the two door-shaped frames (2-2), the shaft seat plate (2-6) is fixedly connected to the upper ends of the two door-shaped frames (2-2) through a folding rod (2-5), a motor frame (2-7) is fixedly connected to the folding rod (2-5), a driving shaft (2-8) is rotatably connected to the right end of the bottom plate (2-1), a gear I (2-9) is fixedly connected to the lower end of the driving shaft (2-8), the gear I (2-9) is meshed with a rack I (1-2), a driving bevel gear (2-10) is fixedly connected to the upper end of the driving shaft (2-8), a short shaft (2-11) is rotatably connected to the door-shaped frame (2-2) at the right end, the middle end of the short shaft (2-11) is fixedly connected with an incomplete gear (2-12), and the rear end of the short shaft (2-11) is fixedly connected with a driven bevel gear (2-13), the driven bevel gears (2-13) are meshed with the driving bevel gears (2-10), four corners of the lower end of the bottom plate (2-1) are rotatably connected with pulleys (2-15) through pulley columns (2-14), and the two pulleys (2-15) at the front end and the rear end are respectively connected in the two pulley grooves (1-1) in a sliding manner;
the rotary driving piece (5) comprises a driving turntable (5-1), purification tube limiting grooves (5-2), sliding groove seats (5-3), sliding grooves (5-4), plug-in pieces (5-5), hinge rods (5-6), round rod grooves (5-7), gear carriers (5-8), gears (5-9) and T-shaped sliding rails (5-10), the driving turntable (5-1) is in clearance fit with the driving shaft (2), a plurality of purification tube limiting grooves (5-2) are distributed on the driving turntable (5-1) along the circumference, the purification tube limiting grooves (5-2) are coaxial with the purification tube bottom slots (4-7), and the left end and the right end of the lower end of the driving turntable (5-1) are symmetrically and fixedly connected with the two sliding groove seats (5-3), the lower ends of two sliding groove seats (5-3) are fixedly connected with two ends of a purification tube chassis (4-6), the outer ends of the two sliding groove seats (5-3) are respectively provided with a sliding groove (5-4), two plug-in components (5-5) are respectively connected in the two sliding grooves (5-4) in a sliding way, a spring is fixedly connected between the plug-in components (5-5) and the sliding grooves (5-4), the outer ends of the two plug-in components (5-5) are respectively inserted in the two inserting grooves (2-4) in a clearance way, the middle ends of the two hinge rods (5-6) are symmetrically hinged on a driving turntable (5-1), the outer ends of the two hinge rods (5-6) are respectively provided with a round rod groove (5-7), the two round rod grooves (5-7) are respectively connected on the two plug-in a sliding way, the inner ends of the two hinge rods (5-6) are respectively lapped on a rotation control mechanism (6), the gear III (5-9) is rotationally connected to two gear carriers (5-8), the two gear carriers (5-8) are fixedly connected to the driving turntable (5-1), and the T-shaped sliding rail (5-10) is fixedly connected to the middle position of the front end of the driving turntable (5-1);
the vibration driving mechanism (4) comprises T-shaped sliding blocks (4-1), circular grooves (4-2), reciprocating discs (4-3), circular rings (4-4), push rods (4-5), a purification tube base plate (4-6), purification tube bottom slots (4-7), a push rod sliding seat (4-8) and a rack II (4-9), the two T-shaped sliding blocks (4-1) are respectively connected to the vertical sliding grooves (2-3) at the left end and the right end in a sliding mode, the circular grooves (4-2) are arranged on the inner sides of the two T-shaped sliding blocks (4-1), the circular rings (4-4) are fixedly connected to the outer ring of the reciprocating disc (4-3), the reciprocating disc (4-3) is connected into the two circular grooves (4-2) in a sliding mode through the circular rings (4-4), the push rods (4-5) are distributed on the upper end of the reciprocating disc (4-3) along the circumference, a plurality of purification tube bottom slots (4-7) are circumferentially distributed on a purification tube chassis (4-6), a plurality of push rod sliding seats (4-8) are circumferentially distributed at the lower end of the purification tube chassis (4-6), the plurality of push rod sliding seats (4-8) are all communicated with the plurality of purification tube bottom slots (4-7), a plurality of push rods (4-5) are respectively and slidably connected with the lower ends of the plurality of push rod sliding seats (4-8), semicircular grooves are arranged at the upper ends of the push rods (4-5), springs are sleeved on the plurality of push rod sliding seats (4-8), the springs are positioned between the purification tube chassis (4-6) and the reciprocating disc (4-3), a rack II (4-9) is fixedly connected on a T-shaped sliding block (4-1) positioned at the right end, and incomplete gears (2-12) are meshed with the rack II (4-9), the reciprocating disc (4-3) and the purification tube chassis (4-6) are in clearance fit with the driving shaft (3), and the two limiting rings (3-3) are respectively positioned at the upper end and the lower end of the purification tube chassis (4-6);
the rotary control mechanism (6) comprises a T-shaped groove sliding seat (6-1), a T-shaped groove (6-2), a push-pull rod (6-3), a rack III (6-4), an inserted rod sliding seat (6-5) and a sliding inserted bar (6-6), a T-shaped groove (6-2) is arranged at the lower end of the T-shaped groove sliding seat (6-1), the T-shaped groove sliding seat (6-1) is connected to a T-shaped sliding rail (5-10) in a sliding mode through the T-shaped groove (6-2), a fastening screw is arranged on the T-shaped groove sliding seat (6-1) and abuts against the T-shaped sliding rail (5-10), the push-pull rod (6-3) is fixedly connected to the rear end of the T-shaped groove sliding seat (6-1), and the front ends of the two hinged rods (5-6) are lapped at two ends of the push-pull rod (6-3), the front end of the push-pull rod (6-3) is fixedly connected with a rack III (6-4), the rack III (6-4) is meshed with the lower end of a gear III (5-9), the upper end of the T-shaped groove sliding seat (6-1) is fixedly connected with an inserting rod sliding seat (6-5), a sliding inserting strip (6-6) is connected onto the inserting rod sliding seat (6-5) in a sliding mode, and the sliding inserting strip (6-6) is meshed with the upper end of the gear III (5-9).
2. The concussion purifier of recombinant nerve growth factor of claim 1, wherein: the driving shaft (3) is provided with a motor (3-1), a rectangular groove (3-2), a limiting ring (3-3) and a gear II (3-4), the driving shaft (3) is fixedly connected to an output shaft of the motor (3-1), the motor (3-1) is fixedly connected to a motor frame (2-7), the lower end of the driving shaft (3) is rotatably connected to a bottom plate (2-1), the lower end of the driving shaft (3) is fixedly connected with the gear II (3-4), the gear II (3-4) is meshed with a rack I (1-2), the upper end of the driving shaft (3) is rotatably connected to a shaft seat plate (2-6), the upper end of the driving shaft (3) is provided with the rectangular groove (3-2), and the rectangular groove (3-2) is positioned below the shaft seat plate (2-6), the middle end of the driving shaft (3) is fixedly connected with two limiting rings (3-3).
3. The concussion purifier of recombinant nerve growth factor of claim 2, wherein: the plug-in components (5-5) are provided with sliding plates (5-5-1), plug boards (5-5-2) and round rods (5-5-3), the sliding plates (5-5-1) are connected in sliding grooves (5-4) in a sliding mode, the lower ends of the sliding plates (5-5-1) are fixedly connected with the plug boards (5-5-2), the plug boards (5-5-2) are inserted in the inserting grooves (2-4) in a clearance mode, the round rods (5-5-3) are fixedly connected at the upper ends of the sliding plates (5-5-1), and the round rods (5-5-3) are connected in the round rod grooves (5-7) in a sliding mode.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910177774.4A CN109776668B (en) | 2018-04-02 | 2018-04-02 | Concussion purifier for recombinant nerve growth factor |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810284397.XA CN108640984B (en) | 2018-04-02 | 2018-04-02 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
| CN201910177774.4A CN109776668B (en) | 2018-04-02 | 2018-04-02 | Concussion purifier for recombinant nerve growth factor |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810284397.XA Division CN108640984B (en) | 2018-04-02 | 2018-04-02 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
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| Publication Number | Publication Date |
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| CN109776668A CN109776668A (en) | 2019-05-21 |
| CN109776668B true CN109776668B (en) | 2022-03-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810284397.XA Expired - Fee Related CN108640984B (en) | 2018-04-02 | 2018-04-02 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
| CN201910177775.9A Withdrawn CN109824770A (en) | 2018-04-02 | 2018-04-02 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
| CN201910177774.4A Expired - Fee Related CN109776668B (en) | 2018-04-02 | 2018-04-02 | Concussion purifier for recombinant nerve growth factor |
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| CN201810284397.XA Expired - Fee Related CN108640984B (en) | 2018-04-02 | 2018-04-02 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
| CN201910177775.9A Withdrawn CN109824770A (en) | 2018-04-02 | 2018-04-02 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
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| CN109225009B (en) * | 2018-11-16 | 2021-04-27 | 新昌县小布点农业发展有限公司 | Test tube vibrates mixing device for chemistry experiments |
| CN109200912B (en) * | 2018-11-16 | 2020-09-08 | 林向亮 | Test tube centrifugation vibrates device for chemistry experiments |
| CN109283038B (en) * | 2018-11-26 | 2021-04-09 | 上海舸海科技有限公司 | Chemical reagent's shock mixing device |
| CN111790595B (en) * | 2020-07-15 | 2022-05-06 | 临沂奥广源达生物科技有限公司 | Separation and purification device with biomaterial handles structure |
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| CN107337725A (en) * | 2017-06-16 | 2017-11-10 | 苏州梅赛生物技术有限公司 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
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2018
- 2018-04-02 CN CN201810284397.XA patent/CN108640984B/en not_active Expired - Fee Related
- 2018-04-02 CN CN201910177775.9A patent/CN109824770A/en not_active Withdrawn
- 2018-04-02 CN CN201910177774.4A patent/CN109776668B/en not_active Expired - Fee Related
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN204251608U (en) * | 2014-12-04 | 2015-04-08 | 威海世利电子科技有限公司 | The automatic rocking equipment of sample tube |
| CN206683924U (en) * | 2017-04-14 | 2017-11-28 | 陈秀丽 | Haemocyte shakes check meter |
| CN107337725A (en) * | 2017-06-16 | 2017-11-10 | 苏州梅赛生物技术有限公司 | A kind of concussion purifier of Recombinant Chinese cobra NGF |
| CN107586716A (en) * | 2017-10-16 | 2018-01-16 | 佛山市顺德区欧罗拉生物科技有限公司 | A kind of biology, the electromagnetic shaker of chemical substance separation and concentration |
| CN213012813U (en) * | 2020-08-28 | 2021-04-20 | 苏州国科医工科技发展(集团)有限公司 | Medical treatment is with blood cell oscillation device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109824770A (en) | 2019-05-31 |
| CN108640984B (en) | 2019-05-17 |
| CN109776668A (en) | 2019-05-21 |
| CN108640984A (en) | 2018-10-12 |
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