CN109758165A - A kind of novel self-help peripheral blood sampling device - Google Patents
A kind of novel self-help peripheral blood sampling device Download PDFInfo
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- CN109758165A CN109758165A CN201910115990.6A CN201910115990A CN109758165A CN 109758165 A CN109758165 A CN 109758165A CN 201910115990 A CN201910115990 A CN 201910115990A CN 109758165 A CN109758165 A CN 109758165A
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- blood sampling
- insulating layer
- heparin tube
- vacuum insulating
- blood
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- 238000010241 blood sampling Methods 0.000 title claims abstract description 61
- 210000005259 peripheral blood Anatomy 0.000 title claims abstract description 22
- 239000011886 peripheral blood Substances 0.000 title claims abstract description 22
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract description 77
- 229960002897 heparin Drugs 0.000 claims abstract description 77
- 229920000669 heparin Polymers 0.000 claims abstract description 77
- 210000004369 blood Anatomy 0.000 claims abstract description 64
- 239000008280 blood Substances 0.000 claims abstract description 64
- 230000001681 protective effect Effects 0.000 claims abstract description 20
- 238000002955 isolation Methods 0.000 claims abstract description 13
- 238000007789 sealing Methods 0.000 claims description 13
- 238000005119 centrifugation Methods 0.000 claims description 12
- 239000003381 stabilizer Substances 0.000 claims description 9
- 239000003146 anticoagulant agent Substances 0.000 claims description 8
- 229940127219 anticoagulant drug Drugs 0.000 claims description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 4
- YRTMFXIMEWYCDX-UHFFFAOYSA-N CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CCNCC Chemical compound CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CCNCC YRTMFXIMEWYCDX-UHFFFAOYSA-N 0.000 claims description 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 239000012954 diazonium Substances 0.000 claims description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-O diazynium Chemical compound [NH+]#N IJGRMHOSHXDMSA-UHFFFAOYSA-O 0.000 claims description 3
- IRXRGVFLQOSHOH-UHFFFAOYSA-L dipotassium;oxalate Chemical compound [K+].[K+].[O-]C(=O)C([O-])=O IRXRGVFLQOSHOH-UHFFFAOYSA-L 0.000 claims description 3
- 239000013013 elastic material Substances 0.000 claims description 3
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 claims description 3
- 239000001103 potassium chloride Substances 0.000 claims description 3
- 235000011164 potassium chloride Nutrition 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims description 3
- BVTHRGZMQHOCOL-UHFFFAOYSA-N OCC(O)(C1(NC(=O)NCNC(=O)NC2(CO)NC(=O)NC2=O)NC(=O)NC1=O)CO Chemical compound OCC(O)(C1(NC(=O)NCNC(=O)NC2(CO)NC(=O)NC2=O)NC(=O)NC1=O)CO BVTHRGZMQHOCOL-UHFFFAOYSA-N 0.000 claims description 2
- 239000001509 sodium citrate Substances 0.000 claims description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- 239000010409 thin film Substances 0.000 claims 2
- UNXHWFMMPAWVPI-QWWZWVQMSA-N D-threitol Chemical compound OC[C@@H](O)[C@H](O)CO UNXHWFMMPAWVPI-QWWZWVQMSA-N 0.000 claims 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 239000005864 Sulphur Substances 0.000 claims 1
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- 210000003813 thumb Anatomy 0.000 description 10
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- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000005457 optimization Methods 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
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- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
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- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- WRYCSMQKUKOKBP-UHFFFAOYSA-N Imidazolidine Chemical compound C1CNCN1 WRYCSMQKUKOKBP-UHFFFAOYSA-N 0.000 description 1
- BWGDAJZRDHAVTI-UHFFFAOYSA-N [3-(hydroxymethyl)imidazolidin-1-yl]methanol Chemical class OCN1CCN(CO)C1 BWGDAJZRDHAVTI-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 229940127090 anticoagulant agent Drugs 0.000 description 1
- 238000012742 biochemical analysis Methods 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
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- 239000003795 chemical substances by application Substances 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
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- 230000009466 transformation Effects 0.000 description 1
Abstract
The present invention provides a kind of self-service peripheral blood sampling devices, including protective cover, heparin tube, vacuum insulating layer, the fixed plug of isolation and blood taking needle.Vacuum insulating layer is arranged in the middle part of heparin tube, and the space between vacuum insulating layer and blood sampling bottom of the tube constitutes vacuum-sealed cavity, and the space between vacuum insulating layer and heparin tube nozzle constitutes accommodating cavity;Wherein, vacuum insulating layer can be turned on so as to generate negative-pressure sucking in negative pressure state in heparin tube.When blood sampling, protective cover is opened, makes blood sampling site pressing blood taking needle to puncture blood sampling site, while opening vacuum insulating layer so that in negative pressure state in heparin tube, so that blood be sucked in heparin tube.Operation of the present invention is simply, conveniently, it is only necessary to which blood sampling person itself operation can be completed;The inlet capacity to blood is enhanced, the collection capacity of blood is increased by introducing negative pressure device relative to traditional peripheral blood sampling device.
Description
Technical field
The invention belongs to fields of biomedicine, are related to a kind of novel self-help peripheral blood sampling device.
Background technique
Blood testing is the most common test object of field of biomedicine, the blood-sampling method generallyd use have venous blood collection and
Finger tip blood sampling.The usual blood sampling volume of venous blood collection is larger, can be from 1 milliliter to milliliters up to a hundred etc..There are many purposes of venous blood collection,
It can be used for biochemistry detection, free nucleic acid detection etc..Meanwhile the device of venous blood collection also there are many kinds of, can be divided into blood plasma,
The heparin tubes such as serum.Therefore, venous blood collection is most widely used Blood collection in current blood testing.But venous blood collection is logical
Specified blood sampling mechanism often is needed, is handled by the doctor and nurse of profession, self-service blood sampling can not be completed at home.
The blood sampling of the tips positions such as finger tip, ear edge is the common blood sampling position taken a blood sample for children and house type, especially family
It is most widely used when the blood sugar test of front yard.Tip blood sampling has the advantages such as easy to operate, amount of bleeding is few.But tip blood sampling due to
Blood only is oozed out by body blood pressure, therefore is difficult to free nucleic acid extraction or subsequent biochemical analysis, and can not isolate
Plasma/serum, it is also difficult to for transporting for long-distance.And many detection projects, especially biochemistry detection and genetic test need at present
Blood plasma and serum are isolated, and current self-service blood-taking device suitable not yet can meet the demand.
Summary of the invention
It can single independent operation the purpose of the present invention is for the different application demand currently taken a blood sample, designing a kind of house type
Peripheral blood sampling device, which has the advantages such as easy to operate, blood sampling volume is more, can transport for long-distance, stability height.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of novel self-help peripheral blood sampling device, including protective cover, heparin tube, vacuum insulating layer, the fixed plug of isolation and blood sampling
Needle,
Protective cover is closed on heparin tube nozzle;
Middle part is arranged in heparin tube in vacuum insulating layer, and the space between vacuum insulating layer and blood sampling bottom of the tube constitutes vacuum sealing
Chamber, the space between vacuum insulating layer and heparin tube nozzle constitute accommodating cavity;Wherein, vacuum insulating layer central area can be opened
It opens so as to generate negative-pressure sucking in negative pressure state in heparin tube;
The fixed plug of isolation is arranged in heparin tube at nozzle;
Heparin tube nozzle is stretched out in blood taking needle one end, and the other end passes through the fixed plug of isolation and protrudes into accommodating cavity, and by the fixed plug of isolation
It is fixed in accommodating cavity;
In use, opening protective cover, make blood sampling site pressing blood taking needle to puncture blood sampling site, while opening vacuum insulating layer
So as to negative-pressure sucking be generated in heparin tube, so that blood be sucked in heparin tube.
Further, the vacuum insulating layer is film, and the film side sealing is fixed on heparin tube inner tubal wall, adopts
Blood position pressing blood taking needle drives blood taking needle to move down and punctures film to form negative-pressure sucking.
Further, the vacuum insulating layer is elastic slice pressing plate, and the elastic slice pressing plate includes annular slab and elastic slice, the ring
The sealing of shape plate outer edge is fixed on heparin tube inner tubal wall, the elastic slice and annular slab locally connect and the elastic slice outer edge and
The annular slab inward flange is fitted close, and blood sampling site pressing blood taking needle drives blood taking needle to move down and pushes elastic slice formation negative pressure suction open
Power.
Further, aperture is provided on the blood sampling tube wall, the vacuum insulating layer is trigger-type vacuum insulating layer,
The trigger-type vacuum insulating layer is made of multiple blades, airtight connection between two neighboring blade, and each blade and blood sampling
It is fitted close between pipe inner tubal wall, slide block is connected on one of blade outer edge, the slide block passes through the aperture
And stretch out outside the aperture, the slide block is made of elastic material and is fitted close with the aperture;Blood sampling site pressing is adopted
Blood needle punctures blood sampling site, while it is mobile to push slide block to make the blade connecting with slide block, and other blade rotations is driven to move
It is dynamic, so that so that trigger-type vacuum insulating layer central area is formed opening generates negative-pressure sucking.
Further, each blade is set as approaching while thickness, with the side on the ironed side of webbing between adjacent blade
Formula fits closely together;Alternatively, each blade be provided on one side protrusion, another side setting it is fluted, adjacent blade it
Between by protrusion matched with groove in a manner of fit closely together.
Further, the heparin tube includes upper tube body and lower tube body, and the upper tube body is threadedly coupled with lower tube body, described
Vacuum insulating layer is arranged in lower tube body.
Further, further include centrifugation auxiliary support, centrifugation auxiliary support around setting outside heparin tube nozzle and with adopt
Blood vessel outer tube wall is connected.
Further, the protective cover is connected via connector with centrifugation auxiliary support.
Further, bottom is placed with anti-coagulants and stabilizer blend in the heparin tube pipe.
Further, the anti-coagulants is selected from potassium oxalate, heparin, sodium chloride, diethylamine tetraacetic acid sylvite and citric acid
Any one in sodium, the stabilizer include dithiothreitol (DTT), mercaptoethanol, imidazolidinyl urea, bis- (methylol) imidazolidines
At least one of base urea and diazonium imidazolidinyl urea.
Compared with the prior art, the invention has the following advantages that
Operation of the present invention is simple and convenient, it is only necessary to which blood sampling person's independent operation can be completed;Relative to traditional peripheral blood sampling device, lead to
Introducing negative pressure device is crossed, the inlet capacity to blood is enhanced, increases the collection capacity of blood.Simultaneously as containing anticoagulant
Agent and stabilizer, blood stability are remarkably reinforced relative to conventional method, can be used for transporting for long-distance and strange land is detected.
Detailed description of the invention
Fig. 1 is that novel self-help peripheral blood sampling device of the invention is closed and opening ways schematic diagram;
Fig. 2 is the side view after the diaphragm type vacuum insulating layer of the embodiment of the present invention is opened;
Fig. 3 is the top view after the diaphragm type vacuum insulating layer of the embodiment of the present invention is opened;
Fig. 4 is the side view after the elastic slice presser type vacuum insulating layer of another embodiment of the present invention is opened;
Fig. 5 is the top view when elastic slice presser type vacuum insulating layer of another embodiment of the present invention is closed;
Fig. 6 is the top view after the elastic slice presser type vacuum insulating layer of another embodiment of the present invention is opened;
Fig. 7 is the side view when trigger-type vacuum insulating layer of further embodiment of this invention is closed;
Fig. 8 is the top view when trigger-type vacuum insulating layer of further embodiment of this invention is closed;
Fig. 9 is the side view when trigger-type vacuum insulating layer of further embodiment of this invention is opened;
Figure 10 is the top view when trigger-type vacuum insulating layer of further embodiment of this invention is opened.
Wherein, 1 protective cover;2 blood taking needles;3 centrifugation auxiliary supports;The fixed plug of 4 isolation;5 heparin tubes;6 vacuum insulating layers;7 is anti-
Solidifying agent and stabilizer blend;8 slide blocks.
Specific embodiment
The invention will be further described combined with specific embodiments below.Following embodiment is only used for clearly illustrating
Technical solution of the present invention, and not intended to limit the protection scope of the present invention.
As shown in Figure 1, a kind of novel self-help peripheral blood sampling device, including protective cover 1, heparin tube 5, vacuum insulating layer 6,
The fixed plug 4 of isolation and blood taking needle 2.
The lid of protective cover 1 closes on 5 nozzle of heparin tube.Preferably, protective cover 1 is connected to the upper of heparin tube 5 via connector
End, to avoid as protective cover 1 is fallen and is lost and caused by pollution.
Middle part is arranged in heparin tube 5 in vacuum insulating layer 6, and the space between 5 bottom of vacuum insulating layer 6 and heparin tube is constituted
Vacuum-sealed cavity, the space between 5 nozzle of vacuum insulating layer 6 and heparin tube constitute accommodating cavity.Wherein, vacuum insulating layer 6 can
It is turned on so as to generate negative-pressure sucking in negative pressure state in heparin tube 5.
The fixed plug 4 of isolation is arranged in heparin tube 5 at nozzle, for sealing the heparin tube 5.In addition, can also rise
To the effect of fixed blood taking needle 2.
5 nozzle of heparin tube is stretched out in 2 one end of blood taking needle, and the other end passes through the fixed plug 4 of isolation and protrudes into accommodating cavity, and by being isolated
Fixed plug 4 is fixed in accommodating cavity.
In use, opening protective cover 1, thumb or other distal locations press 5 nozzle of heparin tube, press so that blood taking needle 2
Thumb or other distal locations are punctured, while opening vacuum insulating layer 6 and being inhaled so as to generate negative pressure in negative pressure state in heparin tube 5
Power, so that blood be sucked in heparin tube 5.
In an embodiment of the present invention, as shown in Fig. 2 to 3, vacuum insulating layer 6 is film, and the film side sealing is solid
It is scheduled on 5 inner tubal wall of heparin tube.Fixed form can be using bonding or other existing fixing means.Film thickness and material requirement
It can guarantee that film is easier to be punctured by blood taking needle 2.When blood sampling, thumb or other distal locations press 5 nozzle of heparin tube, pressing
Film is punctured to form negative-pressure sucking so that blood taking needle 2 is pushed to move down while blood taking needle 2 punctures thumb or other distal locations
Blood to be sucked in heparin tube 5.
In another embodiment of the invention, as shown in Figs. 4-6, vacuum insulating layer 6 is elastic slice pressing plate, the elastic slice pressure
Plate includes annular slab and elastic slice, and the annular slab outer edge sealing is fixed on 5 inner tubal wall of heparin tube, the elastic slice and annular slab
Using part connection and the elastic slice outer edge and the annular slab inward flange are fitted close to form sealing structure, described closely to match
The degree of conjunction requires blood taking needle 2 when pressing blood taking needle 2 that can push elastic slice open.The part connection of elastic slice and annular slab can use
Such as the mode of bonding is realized, it is only necessary to is bonded together elastic slice side and annular slab inward flange, other parts and annular slab
Inward flange matches to form sealing structure, and adhesive strength requires blood taking needle 2 when pressing blood taking needle 2 that can push elastic slice open, still
Elastic slice does not fall out blood sampling bottom of the tube.It is of course also possible to use other connection types are such as hinged etc., as long as meeting above-mentioned want
Asking can.Elastic slice selects the light material with certain elasticity to be made.Annular slab can be made of metal or plastics etc., by using
Sealant is fixed on 5 inner tubal wall of heparin tube.
When blood sampling, thumb or other distal locations press 5 nozzle of heparin tube, pressing so that blood taking needle 2 puncture thumb or its
It pushes blood taking needle 2 to move down while his distal locations and pushes elastic slice formation negative-pressure sucking open to suck blood in heparin tube 5.
In another embodiment of the present invention, as shown in Fig. 7 to 10, it is provided with aperture on 5 tube wall of heparin tube, it is described
Vacuum insulating layer 6 is trigger-type vacuum insulating layer, and the trigger-type vacuum insulating layer is made of multiple blades, the multiple blade
Be made of silica gel, rubber elastomeric material, airtight connection between two neighboring blade, and each blade and heparin tube inner tubal wall it
Between be fitted close.Slide block 8 is connected on one of blade outer edge, the slide block 8 passes through the aperture and stretches out institute
It states outside aperture, the slide block 8 is also made of silica gel, rubber elastomeric material and is fitted close with the aperture.Slide block 8 with
The tight fit of aperture can support the blade connecting with slide block 8, due to being connected with each other between blade, with slide block 8
The blade of connection can support adjacent blade again, and adjacent blade supports next blade again, so that all blades be made to be supported on blood sampling
On 5 inner tubal wall of pipe.
Preferably, the slide block 8 and blade connected to it are integrally formed.
Preferably, each blade is set as approaching while thickness, between adjacent blade in a manner of the ironed side of webbing
It fits closely together, to realize the airtight connection between blade.Alternatively, each blade be provided on one side protrusion, it is another
Side setting is fluted, fits closely together in such a way that protrusion is matched with groove between adjacent blade.
When blood sampling, thumb or other distal locations press 5 nozzle of heparin tube, pressing so that blood taking needle 2 puncture thumb or its
His distal locations, while slide block 8 being pushed to move the blade connecting with slide block 8.Due to slide block 8 and the aperture
It is fitted close by elastic force, so needing to apply certain thrust makes the blade connecting with slide block 8 when pushing slide block 8
It slightly moves, since the blade and other blades use the structure of airtight connection, its movement is again extrudable and drives other rotations
Piece is mobile, so that trigger-type vacuum insulating layer center opening occurs and form negative-pressure sucking.Slide block 8 and the aperture are fitted close
Intensity meet the following conditions: while applying thrust moves the blade connecting with slide block 8 slightly, slide block 8 with it is described
Sealing cooperation can still be maintained in aperture.
It is furthermore preferred that the cross section that the slide block 8 stretches out the part of the aperture is greater than the size of the aperture, this
Sample, the part that slide block 8 stretches out the aperture will be fastened on the outer tube wall of the heparin tube 5.Using this structure, Neng Gou
Slide block 8 is pushed to make further to keep the sealing of slide block 8 and the aperture to cooperate when the blade connecting with slide block 8 is mobile,
And since the part that slide block 8 stretches out the aperture increases, causes user that can be more convenient, easily pushes slide block 8.
In addition, this engaging can be supported on 5 inner tubal wall of heparin tube for all blades plays further supporting role.
As present invention further optimization, the novel self-help peripheral blood sampling device further includes centrifugation auxiliary support 3, institute
Centrifugation auxiliary support 3 is stated to be connected around setting outside 5 nozzle of heparin tube and with 5 outer tube wall of heparin tube.The setting of centrifugation auxiliary support 3
Self-service peripheral blood sampling device of the invention can be made to be placed in play the role of supporting heparin tube 5 when being centrifuged in centrifuge, kept away
Exempt from blood-taking device to entirely fall in eccentric groove.
When setting is centrifuged auxiliary support 3, the protective cover 1 can be connected in the centrifugation auxiliary support 3, protective cover 1
It is connected with centrifugation auxiliary support 3 via connector.Connector can be connecting line, connecting band, connection sheet etc..
As present invention further optimization, the heparin tube 5 is adopted a split structure, including upper tube body and lower tube body,
The upper tube body and lower tube body, which are connected through a screw thread, is assembled into closed structure, and vacuum insulating layer 6 is arranged in lower tube body.Make
When with blood or blood plasma, it is only necessary to after the separation of the upper and lower tube body of heparin tube 5, take out vacuum insulating layer 6.
As present invention further optimization, the heparin tube 5 manages interior bottom and is placed with anti-coagulants and stabilizer blend
7.The anti-coagulants is any one in potassium oxalate, heparin, sodium chloride, diethylamine tetraacetic acid sylvite and sodium citrate,
The stabilizer includes dithiothreitol (DTT), mercaptoethanol, imidazolidinyl urea, Bis(hydroxymethyl)imidazolidinyl urea and diazonium imidazolidine
At least one of base urea.The stability of blood can be improved in the addition of anti-coagulants and stabilizer, convenient for blood long-distance transport and
Strange land detection.
The application method of blood-taking device of the present invention are as follows: protective cover 1 is opened, thumb or other distal locations press heparin tube 5,
So that blood taking needle 2 punctures thumb or other distal locations, while vacuum insulating layer 6 is opened so that in negative pressure state in heparin tube
Blood is sucked in heparin tube 5, heparin tube 5 turns upside down 5-10 times after blood sampling and mixes, closes protective cover 1.Separate blood
When slurry or serum, blood-taking device need to be only placed in centrifuge and be centrifuged.When using blood or blood plasma, by heparin tube 5,
After lower tube body separation, vacuum insulating layer 6 is taken out.
The present invention is disclosed with preferred embodiment above, so it is not intended to limiting the invention, all to take equivalent replacement
Or the scheme technical solution obtained of equivalent transformation, it falls within the scope of protection of the present invention.
Claims (10)
1. a kind of novel self-help peripheral blood sampling device, which is characterized in that including protective cover, heparin tube, vacuum insulating layer, isolation
Fixed plug and blood taking needle,
Protective cover is closed in heparin tube nozzle;
Middle part is arranged in heparin tube in vacuum insulating layer, and the space between vacuum insulating layer and blood sampling bottom of the tube constitutes vacuum sealing
Chamber, the space between vacuum insulating layer and heparin tube nozzle constitute accommodating cavity;Wherein, vacuum insulating layer central area can be opened
It opens so as to generate negative-pressure sucking in negative pressure state in heparin tube;
The fixed plug of isolation is arranged in heparin tube at nozzle;
Heparin tube nozzle is stretched out in blood taking needle one end, and the other end passes through the fixed plug of isolation and protrudes into accommodating cavity, and by the fixed plug of isolation
It is fixed in accommodating cavity;
In use, opening protective cover, make blood sampling site pressing blood taking needle to puncture blood sampling site, while opening vacuum insulating layer
So as to negative-pressure sucking be generated in heparin tube, so that blood be sucked in heparin tube.
2. novel self-help peripheral blood sampling device according to claim 1, which is characterized in that the vacuum insulating layer is thin
Film, the film side sealing are fixed on heparin tube inner tubal wall, and blood sampling site pressing blood taking needle drives blood taking needle to move down will be thin
Film punctures to form negative-pressure sucking.
3. novel self-help peripheral blood sampling device according to claim 1, which is characterized in that the vacuum insulating layer is bullet
Piece pressing plate, the elastic slice pressing plate include annular slab and elastic slice, and the annular slab outer edge sealing is fixed on heparin tube inner tubal wall,
The elastic slice is locally connect with annular slab and the elastic slice outer edge and the annular slab inward flange are fitted close, and blood sampling site is pressed
Pressure blood taking needle drives blood taking needle to move down and pushes elastic slice formation negative-pressure sucking open.
4. novel self-help peripheral blood sampling device according to claim 1, which is characterized in that set on the blood sampling tube wall
It is equipped with aperture, the vacuum insulating layer is trigger-type vacuum insulating layer, and the trigger-type vacuum insulating layer is made of multiple blades,
The multiple blade is made of elastic material, airtight connection between two neighboring blade, and each blade and heparin tube inner tubal wall
Between be fitted close, be connected with slide block on one of blade outer edge, the slide block passes through the aperture and stretches out institute
It states outside aperture, the slide block is made of elastic material and is fitted close with the aperture;Blood sampling site pressing blood taking needle punctures
Blood sampling site, while it is mobile to push slide block to make the blade connecting with slide block, and drives other blade moving in rotations, to make
Trigger-type vacuum insulating layer central area forms opening and generates negative-pressure sucking.
5. novel self-help peripheral blood sampling device according to claim 4, which is characterized in that each blade is set as
It approaches while thickness, is fitted closely together in a manner of the ironed side of webbing between adjacent blade;Alternatively, each blade one
While being provided with, raised, another side setting is fluted, is fitted tightly in such a way that protrusion is matched with groove between adjacent blade
Together.
6. novel self-help peripheral blood sampling device according to claim 1-5, which is characterized in that the heparin tube
Including upper tube body and lower tube body, the upper tube body is threadedly coupled with lower tube body, and the vacuum insulating layer is arranged in lower tube body.
7. novel self-help peripheral blood sampling device according to claim 1-5, which is characterized in that further include centrifugation
Auxiliary support, the centrifugation auxiliary support, which surrounds, to be arranged outside heparin tube nozzle and is connected with heparin tube outer tube wall.
8. novel self-help peripheral blood sampling device according to claim 7, which is characterized in that the protective cover is via connection
Part is connected with centrifugation auxiliary support.
9. novel self-help peripheral blood sampling device according to claim 1-5, which is characterized in that the heparin tube
Bottom is placed with anti-coagulants and stabilizer blend in managing.
10. novel self-help peripheral blood sampling device according to claim 9, which is characterized in that the anti-coagulants be selected from
Any one in potassium oxalate, heparin, sodium chloride, diethylamine tetraacetic acid sylvite and sodium citrate, the stabilizer include two sulphur
At least one of threitol, mercaptoethanol, imidazolidinyl urea, Bis(hydroxymethyl)imidazolidinyl urea and diazonium imidazolidinyl urea.
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Cited By (2)
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CN112006694A (en) * | 2020-09-28 | 2020-12-01 | 嘉检(广州)生物工程技术有限公司 | Vacuum blood sampling device |
CN113189354A (en) * | 2021-04-30 | 2021-07-30 | 重庆国际旅行卫生保健中心(重庆海关口岸门诊部) | Portable quick blood type is just stereotyped and is detected subassembly |
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CN202096211U (en) * | 2011-05-05 | 2012-01-04 | 范英华 | Convenient and quick blood taking device |
CN210095742U (en) * | 2019-02-15 | 2020-02-21 | 浙江大学昆山创新中心 | Novel self-service peripheral blood sampling device |
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DE102005004262A1 (en) * | 2005-01-28 | 2006-08-10 | Wolfgang Folger | Diaphragm for dispensing liquids, gases or pourable goods has equilateral trapezoids which rest with its base against inner leg of neighboring trapezoid and are relocatable against each other |
CN202096211U (en) * | 2011-05-05 | 2012-01-04 | 范英华 | Convenient and quick blood taking device |
CN210095742U (en) * | 2019-02-15 | 2020-02-21 | 浙江大学昆山创新中心 | Novel self-service peripheral blood sampling device |
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CN112006694A (en) * | 2020-09-28 | 2020-12-01 | 嘉检(广州)生物工程技术有限公司 | Vacuum blood sampling device |
CN113189354A (en) * | 2021-04-30 | 2021-07-30 | 重庆国际旅行卫生保健中心(重庆海关口岸门诊部) | Portable quick blood type is just stereotyped and is detected subassembly |
CN113189354B (en) * | 2021-04-30 | 2023-09-19 | 重庆国际旅行卫生保健中心(重庆海关口岸门诊部) | Portable quick blood typing detection assembly |
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