CN109669261A - A kind of cell detection microscope - Google Patents
A kind of cell detection microscope Download PDFInfo
- Publication number
- CN109669261A CN109669261A CN201910076152.2A CN201910076152A CN109669261A CN 109669261 A CN109669261 A CN 109669261A CN 201910076152 A CN201910076152 A CN 201910076152A CN 109669261 A CN109669261 A CN 109669261A
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- Prior art keywords
- axis
- bracket
- camera lens
- bottom plate
- translating device
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
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- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Microscoopes, Condenser (AREA)
Abstract
The invention discloses a kind of cell detection microscopes, including benchmark bottom plate, benchmark bottom plate top side is equipped with Z axis support, the top of Z axis support is equipped with first servo motor, rotation is equipped with the screw rod being axially connected with first servo motor in Z axis support, sliding sleeve is connected to shooting bracket on screw rod, and the top for shooting bracket is equipped with mechanism of taking pictures；The Z axis support of mechanism of taking pictures side is equipped with driving piezoelectric part, and the bottom of Z axis support is equipped with lens assembly；It shoots the benchmark bottom plate below bracket and is equipped with oil holding slot, the top of oil holding slot is equipped with light source corresponding with lens assembly；The Y-axis translating device of benchmark bottom plate, the top of Y-axis translating device is equipped with X-axis translating device, the top of X-axis translating device is equipped with object slide stand and object slide stand vertical adjustment mechanism, vertical direction reinforcing is improved from invention, camera lens shakes scanning focal length up and down and increases, imaging definition is improved, the position precision of imaging is improved.
Description
Technical field
The present invention relates to Electron Microscopy field, in particular to a kind of cell detection microscopes.
Background technique
For cell detection microscope, it is that one kind can carry out centainly the cell sample sample of required detection
The instrument of microexamination detection is carried out after the amplification of degree.Currently, people are using cell detection microscope to human cell tissue
And blood sample carries out microcosmic research, needs to take pictures to microstructure using cell detection microscope, it is clear to obtain
Photo, but current microscope has three in high power sem observation: first is that camera lens shakes scanning focal length very up and down
It is small, if when the image planes of camera lens and not be overlapped sample face, imaging just will appear the situation that half is clear, and half obscures；Second is that existing
The vibration of modern cell detection microscope Y direction when moving horizontally can be transmitted on X-axis slide device, since X-axis is sliding
Moving device is directly contacted with glass slide, and height error is larger between the vibration meeting camera lens and slide of Y direction, influences the position of imaging
Set precision；Third is that cell detection microscope now is small in vertical direction reinforcing, problem above is urgently improved.
Summary of the invention
The technical problem to be solved by the present invention is to overcome prior art disadvantage, provide a kind of cell detection microscope, structure
Rationally, vertical direction reinforcing is improved, imaging definition is improved, improves the position precision of imaging.
In order to solve the above technical problems, technical solution provided by the invention are as follows: a kind of cell detection microscope, including benchmark
Bottom plate, the benchmark bottom plate top side are equipped with Z axis support, and the top of the Z axis support is equipped with first servo motor, institute
It states rotation in Z axis support and is equipped with the screw rod being axially connected with first servo motor, sliding sleeve is connected to shooting branch on the screw rod
Frame, the top of the shooting bracket are equipped with laser barrel, and the top of the laser barrel is equipped with the lens barrel being connected with laser barrel, described
The top of lens barrel is equipped with coupled logical camera；
The Z axis support of the laser barrel side is equipped with driving piezoelectric part, the bottom of the Z axis support be equipped with
The camera lens gusset that is in contact of driving piezoelectric part, rotation is equipped with automatic object lens wheel on the camera lens gusset, described from animal
Mirror wheel is equipped at least one camera lens for communicating with laser barrel, the side of the camera lens gusset be equipped with automatic object lens wheel shaft to
Second servo motor of connection；
Benchmark bottom plate below the shooting bracket is equipped with oil holding slot, and the top of the oil holding slot is equipped with corresponding to camera lens
Light source；
Benchmark bottom plate top is equipped with Y-axis translating device, and the top of the Y-axis translating device is equipped with X-axis translating device,
The top of the X-axis translating device is equipped with object slide stand and object slide stand vertical adjustment mechanism.
As an improvement, the quantity of the camera lens is one.
As an improvement, the X-axis translating device includes X-axis bracket, sliding is equipped with and object slide stand phase on the X-axis bracket
The fixed plate of connection, the X-axis stent side portion are equipped with the third servo motor being axially connected by soft connecting rope with fixed plate,
The X-axis cradle top is additionally provided with the adjuster for adjusting soft connecting rope elasticity, and the softness connecting rope is wirerope.
As an improvement, the Y-axis translating device includes the movable plate being slidably arranged on benchmark bottom plate and passive matrix branch
Frame, the both ends of the passive matrix bracket are respectively equipped with the gag lever post against movable plate side, the benchmark bottom plate be equipped with
The corresponding limited block of movable plate, top and the X-axis bracket of the passive matrix bracket are mutually fixed, and two gag lever posts are close to shifting
The universal wheel being in contact with movable plate on the side of movable plate.
As an improvement, the vertical direction reinforcing workpiece of the driving piezoelectric part is the high thrust pressure that material is piezoelectric ceramics
The detection workpiece of pile, the driving piezoelectric part is 0.1um precision grating scale, and the control power supply of the driving piezoelectric part is adopted
A closed-loop system is formd with high thrust piezoelectric pile, 0.1um precision grating scale and the camera lens gusset that material is piezoelectric ceramics,
The material is that the high thrust piezoelectric pile of piezoelectric ceramics is moved reciprocatingly with precision within 0.2um per second with 600HZ frequency.
As an improvement, the sum of weight of the automatic object lens wheel and at least one camera lens is 5KG.
As an improvement, the translational velocity of the X-axis fixed plate is that 300mm is per second, the object slide stand is translated in fixed plate
In the process because vibration caused by height error within 0.2um.
The advantages of the present invention over the prior art are that: the present invention is through the above technical solutions, to driving piezoelectric part
It is powered, high thrust piezoelectric pile can be reinforced along Z axis (i.e. vertical direction), and high thrust piezoelectric pile and 0.1um precision grating
Ruler forms a closed-loop system, automatic object lens wheel and the camera lens that control weight is 5KG with precision within 0.2um per second with
600HZ frequency moves reciprocatingly, and realizes scanning function, improves vertical direction reinforcing, and camera lens shakes scanning focal length up and down and increases,
Improve imaging definition；Adjuster can improve the mobile precision of X-direction, and universal wheel can eliminate Z-direction power, it is therefore prevented that
In moving process, the vibration occurred under traditional kind of drive is transmitted on Y-axis translating device and X-axis translating device, ensure that
Machine in X-axis in 30mm/ seconds scanning processes, it is between camera lens and slide because height error caused by vibration is in 0.2um
Within, and then improve the position precision of imaging.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention.
Fig. 2 is the enlarged structure schematic diagram in the present invention at A.
As shown in the figure: 1. benchmark bottom plate 2.Z axis support, 21. first servo motor 22. shoots 23. laser barrel of bracket
24. 25. camera 3. of lens barrel driving automatic 33. camera lens 34. second of object lens wheel of 31. camera lens gusset of piezoelectric part 32. is watched
It is solid to take 4. oil holding slot of motor, 41. 51. movable plate of light source 5.Y axis translating device, 52. gag lever post 6.X axis translating device 62.
7. object slide stand of soft 65. adjuster of connecting rope of fixed board 63.X bracing strut 64., 71. object slide stand vertical adjustment mechanism.
Specific embodiment
Present invention will be described in further detail below with reference to the accompanying drawings.
The present invention in the specific implementation, a kind of cell detection microscope, including benchmark bottom plate 1,1 top of benchmark bottom plate
Side is equipped with Z axis support 2, and the top of the Z axis support 2 is equipped with first servo motor 21,2 inward turning of Z axis support
Turn to be equipped with the screw rod being axially connected with first servo motor 21, sliding sleeve is connected to shooting bracket 22, the shooting on the screw rod
The top of bracket 22 is equipped with laser barrel 23, and the top of the laser barrel 23 is equipped with the lens barrel 24 being connected with laser barrel 23, described
The top of lens barrel 24 is equipped with coupled logical camera 25；
The Z axis support 2 of 23 side of laser barrel is equipped with driving piezoelectric part 3, the bottom of the Z axis support 2
Equipped with the camera lens gusset 31 being in contact with driving piezoelectric part 3, rotation is equipped with automatic object lens wheel on the camera lens gusset 31
32, the automatic object lens wheel 32 is equipped at least one camera lens 33 communicated with laser barrel 23, the side of the camera lens gusset 31
Portion is equipped with the second servo motor 34 axially connecting with automatic object lens wheel 32；
The benchmark bottom plate 1 of 22 lower section of shooting bracket is equipped with oil holding slot 4, and the top of the oil holding slot 4 is equipped with and mirror
First 33 corresponding light source 41；
1 top of benchmark bottom plate is equipped with Y-axis translating device 5, and the top of the Y-axis translating device 5 is equipped with X-axis translation dress
6 are set, the top of the X-axis translating device 6 is equipped with object slide stand 7 and object slide stand vertical adjustment mechanism 71.
The quantity of the camera lens 33 is one, and the X-axis translating device 6 includes X-axis bracket 63, on the X-axis bracket 63
It slides equipped with the fixed plate 62 being connected with object slide stand 7,63 side of X-axis bracket is equipped with by soft connecting rope 64 and admittedly
The third servo motor that fixed board 62 is axially connected is additionally provided at the top of the X-axis bracket 63 and adjusts 64 elasticity of soft connecting rope
Adjuster 65, the softness connecting rope 64 is wirerope.
The Y-axis translating device 5 includes the movable plate 51 and passive matrix bracket being slidably arranged on benchmark bottom plate 1, institute
The both ends for stating passive matrix bracket are respectively equipped with the gag lever post 52 against 51 side of movable plate, the benchmark bottom plate 1 be equipped with
The corresponding limited block of movable plate 51, top and 63 phase of X-axis bracket of the passive matrix bracket are fixed, two gag lever posts 52
The universal wheel being in contact with movable plate 51 on the side of movable plate 51.
The vertical direction reinforcing workpiece of the driving piezoelectric part 3 is the high thrust piezoelectric pile that material is piezoelectric ceramics, institute
The detection workpiece for stating driving piezoelectric part 3 is 0.1um precision grating scale, and the control power supply of the driving piezoelectric part 3 uses material
Matter is that high thrust piezoelectric pile, 0.1um precision grating scale and the camera lens gusset 31 of piezoelectric ceramics form a closed-loop system, institute
The high thrust piezoelectric pile that material is piezoelectric ceramics is stated to move reciprocatingly with precision within 0.2um per second with 600HZ frequency.
The sum of weight of the automatic object lens wheel 32 and at least one camera lens 33 is 5KG.
The translational velocity of the X-axis fixed plate 62 is that 30mm is per second, and the object slide stand 7 is in 62 translation motion of fixed plate
Height error is within 0.2um because of caused by vibration.
Wherein, it being powered to driving piezoelectric part 3, high thrust piezoelectric pile can be reinforced along Z axis (i.e. vertical direction), and
High thrust piezoelectric pile and 0.1um precision grating scale form a closed-loop system, the automatic object lens wheel 32 that control weight is 5KG with
Camera lens 33 is moved reciprocatingly with precision within 0.2um per second with 600HZ frequency, is realized scanning function, is improved vertical direction and add
Power, camera lens shake scanning focal length up and down and increase, and improve imaging definition；Adjuster 65 can improve the mobile precision of X-direction,
Universal wheel can eliminate Z-direction power, it is therefore prevented that in moving process, the vibration occurred under traditional kind of drive is transmitted to Y-axis
On translating device and X-axis translating device, ensure that machine in X-axis in 30mm/ seconds scanning processes, between camera lens and slide because
It is height error caused by vibration within 0.2um, and then improves the position precision of imaging.
Above it is exactly a kind of microscopical design feature of cell detection and function and effect, advantage: improves vertical direction
Reinforcing, improves imaging definition, improves the position precision of imaging.
The present invention and its embodiments have been described above, this description is no restricted, shown in the drawings
Only one of embodiments of the present invention, actual structure is not limited to this.All in all if the ordinary skill of this field
Personnel are enlightened by it, without departing from the spirit of the invention, are not inventively designed and the technical solution phase
As frame mode and embodiment, be within the scope of protection of the invention.
Claims (7)
1. a kind of cell detection microscope, including benchmark bottom plate (1), it is characterised in that: benchmark bottom plate (1) top side is set
Have Z axis support (2), the top of the Z axis support (2) is equipped with first servo motor (21), in the Z axis support (2)
Rotation is equipped with the screw rod being axially connected with first servo motor (21), and sliding sleeve is connected to shooting bracket (22), institute on the screw rod
The top for stating shooting bracket (22) is equipped with laser barrel (23), and the top of the laser barrel (23) is equipped with to be connected with laser barrel (23)
Lens barrel (24), the top of the lens barrel (24) is equipped with coupled logical camera (25)；
The Z axis support (2) of laser barrel (23) side is equipped with driving piezoelectric part (3), the Z axis support (2)
Bottom is equipped with the camera lens gusset (31) being in contact with driving piezoelectric part (3), rotates and is equipped on the camera lens gusset (31)
Automatic object lens wheel (32), the automatic object lens wheel (32) are equipped at least one camera lens (33) communicated with laser barrel (23), institute
The side for stating camera lens gusset (31) is equipped with the second servo motor (34) axially connecting with automatic object lens wheel (32)；
Benchmark bottom plate (1) below shooting bracket (22) is equipped with oil holding slot (4), and the top of the oil holding slot (4) is equipped with
Light source (41) corresponding with camera lens (33)；
Benchmark bottom plate (1) top is equipped with Y-axis translating device (5), and the top of the Y-axis translating device (5) is translated equipped with X-axis
The top of device (6), the X-axis translating device (6) is equipped with object slide stand (7) and object slide stand vertical adjustment mechanism (71).
2. a kind of cell detection microscope according to claim 1, it is characterised in that: the quantity of the camera lens (33) is one
It is a.
3. a kind of cell detection microscope according to claim 1, it is characterised in that: the X-axis translating device (6) includes
X-axis bracket (63), sliding is equipped with the fixed plate (62) being connected with object slide stand (7), the X-axis on the X-axis bracket (63)
Bracket (63) side is equipped with the third servo motor being axially connected by soft connecting rope (64) with fixed plate (62), the X-axis
The adjuster (65) for adjusting soft connecting rope (64) elasticity is additionally provided at the top of bracket (63), the softness connecting rope (64) is steel
Cord.
4. a kind of cell detection microscope according to claim 1, it is characterised in that: the Y-axis translating device (5) includes
Movable plate (51) and the passive matrix bracket being slidably arranged on benchmark bottom plate (1), the both ends difference of the passive matrix bracket
Equipped with the gag lever post (52) for abutting movable plate (51) side, the benchmark bottom plate (1) is equipped with limit corresponding with movable plate (51)
Position block, top and the X-axis bracket (63) of the passive matrix bracket are mutually fixed, and two gag lever posts (52) are close to movable plate
(51) universal wheel being in contact with movable plate (51) on side.
5. a kind of cell detection microscope according to claim 1, it is characterised in that: driving piezoelectric part (3)
Vertical direction reinforcing workpiece is the high thrust piezoelectric pile that material is piezoelectric ceramics, the detection workpiece of driving piezoelectric part (3)
Control power supply for 0.1um precision grating scale, driving piezoelectric part (3) uses material for the high thrust piezoelectricity of piezoelectric ceramics
Heap, 0.1um precision grating scale and camera lens gusset (31) form a closed-loop system, and the material is pushing away greatly for piezoelectric ceramics
Pile is forced to move reciprocatingly with precision within 0.2um per second with 600HZ frequency.
6. a kind of cell detection microscope according to claim 1, it is characterised in that: the automatic object lens wheel (32) and extremely
The sum of the weight of a few camera lens (33) is 5KG.
7. a kind of cell detection microscope according to claim 1, it is characterised in that: the X-axis fixed plate (62) is put down
Moving speed is that 30mm is per second, the object slide stand (7) height error because of caused by vibration in fixed plate (62) translation motion
Within 0.2um.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910076152.2A CN109669261A (en) | 2019-01-26 | 2019-01-26 | A kind of cell detection microscope |
| PCT/CN2019/075531 WO2020151039A1 (en) | 2019-01-26 | 2019-02-20 | Cell detection microscope |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910076152.2A CN109669261A (en) | 2019-01-26 | 2019-01-26 | A kind of cell detection microscope |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109669261A true CN109669261A (en) | 2019-04-23 |
Family
ID=66151045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910076152.2A Withdrawn CN109669261A (en) | 2019-01-26 | 2019-01-26 | A kind of cell detection microscope |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN109669261A (en) |
| WO (1) | WO2020151039A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108519665A (en) * | 2018-07-04 | 2018-09-11 | 殷跃锋 | A kind of cell detection microscope |
| CN111337347A (en) * | 2020-03-13 | 2020-06-26 | 浙江大学 | Plant micro-mechanics detection device and detection method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116381892B (en) * | 2023-04-21 | 2023-12-12 | 广东工业大学 | Two-stage macro-micro camera lens focusing device based on direct-drive type air floatation platform |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100495109C (en) * | 2006-06-19 | 2009-06-03 | 中国科学院上海光学精密机械研究所 | modular scanning probe microscope |
| JP2010097061A (en) * | 2008-10-17 | 2010-04-30 | Olympus Corp | Coarse and fine adjustment device and automatic focusing device |
| CN204373680U (en) * | 2014-12-24 | 2015-06-03 | 上海电气集团股份有限公司 | A kind of five degree of freedom The Cloud Terrace |
| CN205427298U (en) * | 2016-03-11 | 2016-08-03 | 宁波键一生物科技有限公司 | A microscope for living cell culture surveys |
| CN107015525A (en) * | 2017-03-16 | 2017-08-04 | 南通大学 | A kind of micro-displacement control platform and application method observed suitable for micro-fluidic chip |
| CN108519665B (en) * | 2018-07-04 | 2024-06-07 | 殷跃锋 | Cell detection microscope |
-
2019
- 2019-01-26 CN CN201910076152.2A patent/CN109669261A/en not_active Withdrawn
- 2019-02-20 WO PCT/CN2019/075531 patent/WO2020151039A1/en active Application Filing
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108519665A (en) * | 2018-07-04 | 2018-09-11 | 殷跃锋 | A kind of cell detection microscope |
| CN108519665B (en) * | 2018-07-04 | 2024-06-07 | 殷跃锋 | Cell detection microscope |
| CN111337347A (en) * | 2020-03-13 | 2020-06-26 | 浙江大学 | Plant micro-mechanics detection device and detection method thereof |
| CN111337347B (en) * | 2020-03-13 | 2021-07-20 | 浙江大学 | Plant micro-mechanics detection device and detection method thereof |
| WO2021179609A1 (en) * | 2020-03-13 | 2021-09-16 | 浙江大学 | Micromechanical plant measurement apparatus and measurement method therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020151039A1 (en) | 2020-07-30 |
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| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190423 |
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| WW01 | Invention patent application withdrawn after publication |