CN109662799A - Rat fixator for thermometric in electromagnetic radiation environment - Google Patents

Rat fixator for thermometric in electromagnetic radiation environment Download PDF

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Publication number
CN109662799A
CN109662799A CN201811534816.7A CN201811534816A CN109662799A CN 109662799 A CN109662799 A CN 109662799A CN 201811534816 A CN201811534816 A CN 201811534816A CN 109662799 A CN109662799 A CN 109662799A
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China
Prior art keywords
rat
outer cylinder
thermometric
fixed plate
electromagnetic radiation
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CN201811534816.7A
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Chinese (zh)
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CN109662799B (en
Inventor
王丽峰
邹勇
胡向军
智维佳
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Institute of Pharmacology and Toxicology of AMMS
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Institute of Pharmacology and Toxicology of AMMS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Animal Husbandry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The invention discloses a kind of rat fixators for thermometric in electromagnetic radiation environment, are related to biomedical experiment clothing arts.Rat fixator includes inner cylinder, outer cylinder, outer cylinder fixed plate, screw and thermometer support.Outer cylinder is used cooperatively with inner cylinder, for guiding rat to pierce and fixing the rat.Outer cylinder fixed plate is vertical with outer cylinder one end and is fixedly connected, and is used to support outer cylinder and exposes the anus area of rat, and direction of the adjustable rat position relative to radiation field.Screw is used to fix across outer cylinder and with inner cylinder.Thermometer support relative level is vertical, is used to support thermometer.Wherein, when thermometric, rat is fixed by inner cylinder, outer cylinder, outer cylinder fixed plate and screw jointly.Using the rat fixator, only thermometric need to be can be realized by fixed be placed under electromagnetic environment of the rat fixator in rat, entire thermometric process is unattended, and operator is not exposed in electromagnetic environment, ensure that safety.

Description

Rat fixator for thermometric in electromagnetic radiation environment
Technical field
The present invention relates to biomedical experiment clothing arts, more particularly, to one kind for surveying in electromagnetic radiation environment The rat fixator of temperature.
Background technique
With the development of wireless telecommunications system such as radar, mobile phone etc., influence of the electromagnetic radiation to human health is increasingly subject to Concern.Electromagnetic radiation biological effect research is to assess the effective means of electromagnetic radiation potential hazard, wherein temperature is electromagnetic radiation Very important Testing index in biological effect research.It is both the basic index for evaluating the fuel factor extent of injury, is also to discriminate between The important indicator of fuel factor and non-thermal effect.
Rat is to carry out animal Occupational exposure to magnetic fields to test one of most common experimental animal, in the Occupational exposure to magnetic fields mistake of different condition Cheng Zhong need to be monitored the body temperature of rat, with the situation of change of rat temperature during clear electromagnetic radiation.Common thermometric There are two types of methods.One is IR thermometry, this method does not need fixed rat, but can only measure the shell temperature of rat, Shell temperature can not represent its DIE Temperature.Another kind measures rat anus by mercurial thermometer or thermocouple thermometer Temperature can represent DIE Temperature, but this method needs fixed rat, generally cooperates thermometric by two people at present, and a people grabs Rat is taken, a people measures the anus temperature of rat.
The process of above-mentioned measurement rat anus temperature needs two people cooperation, considers the safety of personnel, thermometric can not be in electromagnetism spoke It penetrates in environment and carries out, otherwise operator will receive the potential hazard of electromagnetic radiation.
Summary of the invention
The present invention is directed at least solve one of the technical problems existing in the prior art.For this purpose, the present invention proposes a kind of use The rat fixator of thermometric in electromagnetic radiation environment.
A kind of rat fixator for thermometric in electromagnetic radiation environment, comprising:
Inner cylinder;
Outer cylinder is placed on outside the inner cylinder, is used cooperatively with the inner cylinder, described big for guiding rat to pierce and fixing Mouse;
Outer cylinder fixed plate, it is vertical with described outer cylinder one end and be fixedly connected, be used to support the outer cylinder and make the rat Anus area expose, and direction of the adjustable rat position relative to radiation field;
The inner cylinder is fixed on the outer cylinder for fixing across the outer cylinder and with the inner cylinder by screw;With
Thermometer support, relative level is vertical, is used to support thermometer, to measure the anus temperature of the rat;
Wherein, when thermometric, institute is fixed by the inner cylinder, the outer cylinder, the outer cylinder fixed plate and the screw jointly State rat.
Further, the inner cylinder is the cylinder of another end opening closed at one end, and the open end is for making the rat It pierces, the closed end is used to limit the displacement of the rat, and the closed end has the air hole penetrated through along its axis, to protect Rat eupnea is demonstrate,proved, the cylinder is axially arranged with screw hole, to accommodate the screw.
Further, the quantity of the screw hole is multiple and sets in an arrangement, is set in distance between screw hole two-by-two, with suitable Answer the rat of different length.
Further, the outer cylinder is the cylinder of both ends open, and one end of the close inner cylinder is along its diameter in the outer cylinder To through-hole is equipped with, with by the screw, the outer cylinder center is equipped with aperture, described in order to guide the rat to pierce The outer cylinder other end is along the outer cylinder opening being connected with the aperture is axially arranged with, to guide the tail of the rat to pass through.
Further, the quantity of the through-hole is multiple, is cooperated by the through-hole of the screw hole and different location, with setting The exposure angle of the rat.
Further, the outer cylinder fixed plate is fixedly connected with the one end for being equipped with outer cylinder opening in the outer cylinder, institute Outer cylinder fixed plate center position on the upper side is stated equipped with through hole, to expose the anus of the rat, the top of the outer cylinder fixed plate End is equipped with the outer cylinder fixed plate opening being connected with the through hole, the outer cylinder fixed plate opening and the outer cylinder vertically downward Opening in communication, so that rat tail passes through and thermometric operation.
Further, the outer cylinder fixed plate is in regular hexagon, needs to adjust the rat face electricity with experimental The direction of magnetic wave.
Further, the thermometer support relative level is vertical, has rack body, is equipped at the rack body Penetrate through its front and rear surfaces shelves hole, to support the thermometer.
Further, the thermometer support also has pedestal, is fixedly connected with the rack body, to support the branch Frame ontology.
Further, the inner cylinder, the outer cylinder, the outer cylinder fixed plate, the screw and the thermometer support are equal It is made of organic glass, to be suitable for Occupational exposure to magnetic fields environment.
Rat fixator of the present invention for thermometric in electromagnetic radiation environment, passes through inner cylinder, outer cylinder, outer cylinder fixed plate And screw forms rat fixed structure, exposes rat anus by outer cylinder fixed plate, thermometer one end is supported on thermometer support On, the thermometer other end is inserted into rat anus, and measurement rat anus temperature can be realized.Using the rat fixator, only needing will be big Thermometric can be realized in fixed be placed under electromagnetic environment of mouse, and entire thermometric process is unattended, and operator is not exposed to electricity In magnetic environment, personnel safety ensure that.
Additional aspect and advantage of the invention will be set forth in part in the description, and will partially become from the following description Obviously, or practice through the invention is recognized.
Detailed description of the invention
Above-mentioned and/or additional aspect of the invention and advantage will become from the description of the embodiment in conjunction with the following figures Obviously and it is readily appreciated that, in which:
Fig. 1 be it is provided in an embodiment of the present invention it is a kind of in electromagnetic radiation environment the rat fixator of thermometric it is schematic Explosive view;
Fig. 2 is the structural schematic diagram of screw provided in an embodiment of the present invention.
Appended drawing reference:
100 rat fixators
10 inner cylinders,
11 closed ends, 12 open ends, 13 air holes, 14 screw holes,
20 outer cylinders,
21 through-holes, 22 apertures, 23 outer cylinders opening,
30 outer cylinder fixed plates,
31 through holes, 32 outer cylinder fixed plates opening, 33 grooves,
40 screws,
50 thermometer supports,
51 rack bodies, 52 shelve hole, 53 pedestals.
Specific embodiment
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached The embodiment of figure description is exemplary, and for explaining only the invention, and is not considered as limiting the invention.
Fig. 1 be it is provided in an embodiment of the present invention it is a kind of in electromagnetic radiation environment the rat fixator of thermometric it is schematic Explosive view.Fig. 2 is the structural schematic diagram of screw provided in an embodiment of the present invention.As shown in Figure 1, the present invention mentions referring also to Fig. 2 A kind of rat fixator 100 for thermometric in electromagnetic radiation environment is supplied, generality may include: inner cylinder 10, outer cylinder 20, outer Cylinder fixed plate 30, screw 40 (referring to fig. 2) and thermometer support 50.Outer cylinder 20 is placed on outside the inner cylinder 10, with the inner cylinder 10 are used cooperatively, for guiding rat to pierce and fixing the rat.Preferably, the internal diameter phase of the outer diameter of inner cylinder 10 and outer cylinder 20 Matching, in order to which the inner cylinder 10 is nested into the outer cylinder 20.It is highly preferred that inner cylinder 10 can be just inserted into outer cylinder 20. Outer cylinder fixed plate 30 is vertical with described 20 one end of outer cylinder and is fixedly connected, and is used to support the outer cylinder 20 and makes the anus of the rat Door position is exposed, and direction of the adjustable rat position relative to radiation field.Screw 40 (referring to fig. 2) is used for across institute It states outer cylinder 20 and is fixed with the inner cylinder 10, the inner cylinder 10 is fixed at the outer cylinder 20.Preferably, (the ginseng of screw 40 See Fig. 2) it is butterfly screws, in order to operate.50 relative level of thermometer support is vertical, is used to support thermometer, with measurement The anus temperature of the rat.Wherein, when thermometric, pass through the inner cylinder 10, the outer cylinder 20, the outer cylinder fixed plate 30 and the spiral shell Silk 40 fixes the rat jointly.
When thermometric, the inner cylinder 10 and the outer cylinder 20 are horizontal positioned, and operator is to hold outer cylinder 20 and inner cylinder 10 on the other hand Junction, inner cylinder 10 are embedded in 20 a part of outer cylinder, and then operator's another hand, which carries rat tail, makes rat head from outer cylinder 20 pierce in inner cylinder 10, are fixed after then adjusting appropriate length by screw 40, so that rat is in comfortable state can not move again Bullet.The thermometer passes through the thermometer support 50 and is inserted into the anus of the rat, to measure the anus temperature of the rat.
Rat fixator 100 of the present invention for thermometric in electromagnetic radiation environment is led to using the feature of getting into the cave of rat It crosses inner cylinder 10, outer cylinder 20, outer cylinder fixed plate 30 and screw 40 and forms rat fixed structure, can easily fix rat.It is logical It crosses outer cylinder fixed plate 30 and exposes rat anus, thermometer one end is supported on thermometer support 50, and the insertion of the thermometer other end is big Measurement rat anus temperature can be realized in mouse anus, easy to use, easy to operate.Using the rat fixator 100, only needing will be big Thermometric can be realized in fixed be placed under electromagnetic environment of mouse, and entire thermometric process is unattended, and operator is not exposed to electricity In magnetic environment, safety ensure that.
In addition, it is the configuration of the present invention is simple, reliable, convenient for operation and cleaning.
In addition, saving manpower not only safe using rat fixator 100 of the present invention, but also it is applied widely.This Invention can be adapted for the experimental implementations such as venous blood sampling, intraperitoneal injection, the acupuncture of rat.
Inventor is in the implementation of the present invention, it was found that existing to take blood, intraperitoneal injection, acupuncture etc. for tail vein The rat fixator of experimental implementation, there are fixator design is unreasonable, when operation, need to be forced to fix, and easily injure or enrage rat, Both it is unfavorable for testing or has security risk to operator.And rat fixator 100 of the present invention is used, it is upper due to using Structure is stated, therefore not only can guarantee rat fixation, but also rat is made to be in a pleasant state, is not only advantageous to test And operator is safer.
In the present embodiment, the inner cylinder 10 is the cylinder of another end opening closed at one end, and the open end 12 is for making institute It states rat to pierce, the closed end 11 is used to limit the displacement of the rat, and the closed end 11 has to be penetrated through along its axis Air hole 13, to guarantee that rat eupnea, the cylinder are axially arranged with screw hole 14, to accommodate the screw 40.
In the present embodiment, the quantity of the screw hole 14 is multiple and sets in an arrangement, is set between screw hole 14 in interval two-by-two It sets, to adapt to the rat of different length, so not only structure is simple by the present invention, and has different building shape rat degree of regulation good Advantage.In the present embodiment, the top of inner cylinder 10 is equipped with row's screw hole 14.
In the present embodiment, the outer cylinder 20 is the cylinder of both ends open.Close to the one of the inner cylinder 10 in the outer cylinder 20 End is radially equipped with through-hole 21, to pass through the screw 40.20 center of outer cylinder is equipped with aperture 22, in order to guide It states rat to pierce, the aperture 22 is circular hole.20 other end of outer cylinder along be axially arranged be connected with the aperture 22 it is outer Cylinder opening 23, so that the operator pulls the tail of the rat, i.e., guidance rat tail passes through outer cylinder opening 23.
In the present embodiment, the quantity of the through-hole 21 be it is multiple, matched by the through-hole 21 of the screw hole 14 and different location It closes, to set the exposure angle of the rat.In the present embodiment, outer cylinder 20 is close to the upper and lower, left and right of 10 side of inner cylinder radial direction Four direction respectively has a through-hole 21, to adapt to different rat exposure positions, i.e. back side exposure, veutro exposure, left side exposure Or right side exposure.Certainly, in other embodiments, the through-hole 21 of more direction can also be increased as needed.Select different spiral shells Hole 14 and through-hole 21 combine the rat being adapted to without figure length, and adapt to different rat exposure positions.
In the present embodiment, the outer cylinder fixed plate 30 is fixed with the one end for being equipped with outer cylinder opening 23 in the outer cylinder 20 Connection.It is fixed on its anus present position after inner cylinder 10 according to rat, position on the upper side is set at 30 center of outer cylinder fixed plate There is through hole 31, to expose the anus of the rat.The top of the outer cylinder fixed plate 30 is equipped with and the perforation vertically downward The outer cylinder fixed plate opening 32 that hole 31 is connected, the outer cylinder fixed plate opening 32 are connected with outer cylinder opening 23, so as to It is operated in thermometric.
More specifically, in the present embodiment, outer cylinder fixed plate 30 and outer cylinder 20 match the circular groove 33 being equipped on one side, outside In 20 pluggable circular grooves 33 of cylinder, fixed by organic glass glue.Rat fixator 100 can be stably placed in this way On horizontal plane.Certainly, the fixed form between outer cylinder 20 and outer cylinder fixed plate 30 can also be interference fit, be threadedly coupled etc. Other are fixedly connected with mode.
In the present embodiment, the outer cylinder fixed plate 30 is in regular hexagon, is needing to adjust the rat just with experimental To the direction of electromagnetic wave.
In the present embodiment, 50 relative level of thermometer support is vertical, has rack body 51, the rack body It is equipped at 51 and penetrates through its front and rear surfaces and shelve hole 52, to support the thermometer.
The habit of getting into the cave of rat is utilized in this way, it is easy to which induced rat pierces the aperture 22 of outer cylinder 20, and then pierces inner cylinder 10 inside, then the outer cylinder along 22 right side of aperture at 20 middle part of outer cylinder is open on the upside of 23 and 30 through hole of outer cylinder fixed plate 31 Outer cylinder fixed plate opening 32 pull rat tails, be located at rat-tail portion at the through hole 31 in outer cylinder fixed plate 30.It adjusts simultaneously The depth of nesting of section inner cylinder 10 and outer cylinder 20 is fixed on rat in inner cylinder 10, outer cylinder 20 and outer cylinder fixed plate 30.It is mentioned when upwards When rat-tail, the exposure of its anus can be made, thermometer can be can be readily intercalated into and carry out thermometric operation.After thermometer is inserted into rat anus, Its other end is placed on thermometer support 50, have on bracket it is several shelve hole 52, pass through and adjust thermometer support 50 and rat The distance of fixator 100 and selection suitably shelve hole 52, so that thermometer is kept certain inclination angle, anal side is low, thermometer branch 50 side of frame is high, makes to measure chronothermometer position and keeps stablizing, and is not easily susceptible to the activity of rat anal muscle and ejects the shadow of thermometer It rings.
Further, the thermometer support 50 also has pedestal 53, is fixedly connected with the rack body 51, with support The rack body 51.
Further, the inner cylinder 10, the outer cylinder 20, the outer cylinder fixed plate 30, the screw 40 and the temperature Meter bracket 50 is all made of organic glass and is made, to avoid the influence during Occupational exposure to magnetic fields to magnetic distribution.Therefore present invention electricity Magnetic good compatibility can be applied in all kinds of electromagnetic environments.The material of certain all components can also be that other can be avoided electricity The material of influence during magnetic storm dew to magnetic distribution, such as plastics, rubber material.The present invention fully considers electromagnetic environment It is operated with thermometric, provides a kind of rat fixator 100 that can be used under electromagnetic environment measuring rat core temperature.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " illustrative examples ", The description of " example ", " specific example " or " some examples " etc. means specific features described in conjunction with this embodiment or example, knot Structure, material or feature are included at least one embodiment or example of the invention.In the present specification, to above-mentioned term Schematic representation may not refer to the same embodiment or example.Moreover, specific features, structure, material or the spy of description Point can be combined in any suitable manner in any one or more of the embodiments or examples.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not A variety of change, modification, replacement and modification can be carried out to these embodiments in the case where being detached from the principle of the present invention and objective, this The range of invention is defined by the claims and their equivalents.

Claims (10)

1. a kind of rat fixator for thermometric in electromagnetic radiation environment characterized by comprising
Inner cylinder;
Outer cylinder is placed on outside the inner cylinder, is used cooperatively with the inner cylinder, for guiding rat to pierce and fixing the rat;
Outer cylinder fixed plate, it is vertical with described outer cylinder one end and be fixedly connected, be used to support the outer cylinder and make the anus of the rat Door position is exposed, and direction of the adjustable rat position relative to radiation field;
The inner cylinder is fixed on the outer cylinder for fixing across the outer cylinder and with the inner cylinder by screw;With
Thermometer support, relative level is vertical, is used to support thermometer, to measure the anus temperature of the rat;
Wherein, it when thermometric, is fixed jointly by the inner cylinder, the outer cylinder, the outer cylinder fixed plate and the screw described big Mouse.
2. the rat fixator according to claim 1 for thermometric in electromagnetic radiation environment, which is characterized in that in described Cylinder is the cylinder of another end opening closed at one end, and the open end is for piercing the rat, and the closed end is for limiting The displacement of the rat, the closed end has the air hole penetrated through along its axis, to guarantee rat eupnea, the cylinder Be axially arranged with screw hole, to accommodate the screw.
3. the rat fixator according to claim 2 for thermometric in electromagnetic radiation environment, which is characterized in that the spiral shell The quantity in hole is multiple and sets in an arrangement, is set in distance between screw hole two-by-two, to adapt to the rat of different length.
4. the rat fixator according to claim 2 for thermometric in electromagnetic radiation environment, which is characterized in that described outer Cylinder is the cylinder of both ends open, and one end of the close inner cylinder is radially equipped with through-hole in the outer cylinder, to pass through the spiral shell Silk, the outer cylinder center is equipped with aperture, and in order to guide the rat to pierce, the outer cylinder other end edge is axially arranged with and institute The outer cylinder opening that aperture is connected is stated, to guide the tail of the rat to pass through.
5. the rat fixator according to claim 4 for thermometric in electromagnetic radiation environment, which is characterized in that described logical The quantity in hole be it is multiple, by the through-hole of the screw hole and different location cooperate, to set the exposure angle of the rat.
6. the rat fixator according to claim 4 for thermometric in electromagnetic radiation environment, which is characterized in that described outer Cylinder fixed plate is fixedly connected with the one end for being equipped with outer cylinder opening in the outer cylinder, outer cylinder fixed plate center position on the upper side Through hole is installed, to expose the anus of the rat, the top of the outer cylinder fixed plate is equipped with and the perforation vertically downward The outer cylinder fixed plate opening that hole is connected, the outer cylinder fixed plate opening and the outer cylinder opening in communication, in order to big rat-tail Bar by and thermometric operation.
7. the rat fixator according to claim 6 for thermometric in electromagnetic radiation environment, which is characterized in that described outer Cylinder fixed plate is in regular hexagon, with the experimental direction for needing to adjust the rat face electromagnetic wave.
8. the rat fixator according to claim 1 for thermometric in electromagnetic radiation environment, which is characterized in that the temperature Degree meter bracket relative level is vertical, has rack body, be equipped at the rack body penetrate through its front and rear surfaces shelve hole, To support the thermometer.
9. the rat fixator according to claim 8 for thermometric in electromagnetic radiation environment, which is characterized in that the temperature Degree meter bracket also has pedestal, is fixedly connected with the rack body, to support the rack body.
10. the rat fixator according to claim 1 to 9 for thermometric in electromagnetic radiation environment, feature It is, the inner cylinder, the outer cylinder, the outer cylinder fixed plate, the screw and the thermometer support are all made of organic glass It is made, to be suitable for electromagnetic radiation environment.
CN201811534816.7A 2018-12-14 2018-12-14 Rat fixer for measuring temperature in electromagnetic radiation environment Active CN109662799B (en)

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CN112773549A (en) * 2019-11-07 2021-05-11 中国人民解放军军事科学院军事医学研究院 Positionable rodent immobilization device for electromagnetic radiation exposure
CN113663227A (en) * 2021-09-07 2021-11-19 华东医院 All-wrapping mouse hind limb ultraviolet radiation fixator
CN117064345A (en) * 2023-10-18 2023-11-17 中国人民解放军军事科学院军事医学研究院 Body temperature measuring device for mouse heat production research

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CN108309495A (en) * 2018-03-05 2018-07-24 中国人民解放军陆军军医大学第附属医院 A kind of Multi-function quick assembling administration mouse cylinder
CN209916274U (en) * 2018-12-14 2020-01-10 中国人民解放军军事科学院军事医学研究院 Rat fixer for measuring temperature in electromagnetic radiation environment

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CN112773549A (en) * 2019-11-07 2021-05-11 中国人民解放军军事科学院军事医学研究院 Positionable rodent immobilization device for electromagnetic radiation exposure
CN113663227A (en) * 2021-09-07 2021-11-19 华东医院 All-wrapping mouse hind limb ultraviolet radiation fixator
CN113663227B (en) * 2021-09-07 2024-05-31 华东医院 Full-wrapping mouse hind limb ultraviolet radiation fixer
CN117064345A (en) * 2023-10-18 2023-11-17 中国人民解放军军事科学院军事医学研究院 Body temperature measuring device for mouse heat production research
CN117064345B (en) * 2023-10-18 2023-12-19 中国人民解放军军事科学院军事医学研究院 Body temperature measuring device for mouse heat production research

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