CN215535277U - Mouse fixing device - Google Patents

Mouse fixing device Download PDF

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Publication number
CN215535277U
CN215535277U CN202121642725.2U CN202121642725U CN215535277U CN 215535277 U CN215535277 U CN 215535277U CN 202121642725 U CN202121642725 U CN 202121642725U CN 215535277 U CN215535277 U CN 215535277U
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China
Prior art keywords
mouse
device body
hole
fixing device
head
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CN202121642725.2U
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Chinese (zh)
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李彬
刘璐
赵洛鹏
魏江艳
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Beijing Traditional Chinese Medicine Hospital
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Beijing Traditional Chinese Medicine Hospital
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Abstract

The utility model discloses a mouse fixing device, which is used for fixing a mouse to measure facial mechanical pain of the mouse and comprises: the device body is cylindrical, the head limiting part is connected to one end of the device body, the head limiting part is conical, the area of the head limiting part in the direction away from the device body is gradually reduced, and the partition board is movably installed in the device body and located at one end, away from the head limiting part, of the device body. The movable partition plate is arranged, so that the fixing space of the mouse fixing device can be changed, the mouse fixing device can be applied to mice with different volumes, the mouse fixing device disclosed by the embodiment of the utility model can be widely applied, the fixing stability of the mouse can be improved, the comfort of the mouse can be ensured, and the accuracy of data during measurement can be improved.

Description

Mouse fixing device
Technical Field
The utility model relates to the field of animal detection instruments, in particular to a mouse fixing device.
Background
Pain is one of the most common clinical symptoms, is associated with a variety of diseases, and affects the course of the disease and the clinical therapeutic effect. Pain affects the mind and mind of the patient. The pain threshold determination is a common method for pain research, and accurate and objective measurement of the pain threshold plays an important role in diagnosis of diseases, evaluation of treatment effects and judgment of prognosis. Mechanical pain refers to the mechanical deformation of tissue under the action of external force, and when the deformation degree exceeds the threshold value of mechanical nociceptors, the nociceptors are activated to generate mechanical pain. After the external force is removed, the tissue is reshaped and the pain disappears. In basic studies of pain, one of the main methods for determining the behavior of model animals includes heat-induced pain, touch-induced pain, and the like. Mechanical pain determination mainly adopts von-Frey (von Frey membranes) cilia at present, and the principle is to use cilia with different specifications to stimulate repeatedly for many times and observe the occurrence of hyperalgesia of animals after inflammation or nerve injury. The mechanical pain measurement of the mouse face is to measure the pain of the mouse by using von-Frey cilia to give induction pain to the mouse face, but at present, a fixing device which can be widely used for measuring the mechanical pain of the mouse face without adjusting the mouse body type is not provided.
SUMMERY OF THE UTILITY MODEL
The present invention is directed to solving at least one of the problems of the prior art. Therefore, an object of the present invention is to provide a mouse fixing device, which can adjust the accommodating volume of the fixing device according to the body types of different mice, and can be widely applied.
The mouse fixing device according to the present invention for fixing a mouse to measure mechanical pain of a face of the mouse includes: the device body is cylindrical; the head limiting part is connected to one end of the device body, the head limiting part is in a cone cylinder shape, and the area of the head limiting part is gradually reduced in the direction away from the device body; the partition plate is movably installed in the device body and is located at one end, far away from the head limiting part, of the device body.
According to the mouse fixing device, the movable partition plate is arranged, so that the fixing space of the mouse fixing device can be changed, the mouse fixing device can be applied to mice with different volumes, the mouse fixing device disclosed by the embodiment of the utility model can be widely applied, the fixing stability of the mouse can be improved, the comfort of the mouse can be ensured, and the accuracy of data during measurement can be improved.
In some embodiments, the partition plate is provided with an adjusting member for connecting the device body.
Specifically, be provided with the regulation hole on the device body, the regulation hole is followed the length direction of device body sets up, the regulating part cooperation is in on the regulation hole, the regulating part is when loosening along the regulation hole is portable.
Optionally, the adjusting part is a screw, a threaded hole is formed in the partition plate, and the screw is connected to the threaded hole.
In some embodiments, the adjustment aperture is open at an end distal from the head restraint.
Optionally, the partition panel is provided with a tail avoidance notch.
In some embodiments, the mouse fixation device further comprises: and the fixed plate is fixedly arranged at the bottom of the device body.
In some embodiments, the device body is provided with a vent hole, the vent hole comprising: the device comprises a first vent hole and a second vent hole, wherein the first vent hole is positioned on the two horizontal sides of the device body, and the second vent hole is positioned on the top of the device body.
Optionally, a test hole is provided in the head limiting part, and the test hole is located at an end of the head limiting part far from the device body.
Specifically, a plurality of spaced third vent holes surrounding the test hole are arranged on the head limiting part.
Additional aspects and advantages of the utility model will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the utility model.
Drawings
The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:
FIG. 1 is a perspective external view of a mouse fixing device according to an embodiment of the present invention;
FIG. 2 is a side view of a mouse fixing device according to an embodiment of the present invention;
FIG. 3 is a top view of a mouse fixing device according to an embodiment of the present invention;
FIG. 4 is a front view of a mouse fixture according to an embodiment of the present invention;
fig. 5 is a schematic structural view of a partition plate of a mouse fixing device according to an embodiment of the present invention.
Reference numerals:
a mouse fixing device 100,
A device body 1, an adjusting hole 11, a vent hole 12, a first vent hole 121, a second vent hole 122,
A head limiting part 2, a test hole 21, a third vent hole 22,
A partition plate 3, an avoiding gap 30,
An adjusting part 4,
A fixed plate 5,
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the accompanying drawings are illustrative only for the purpose of explaining the present invention, and are not to be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "length," "width," "height," "upper," "lower," "front," "rear," "vertical," "horizontal," "top," "bottom," "inner," "outer," "circumferential," and the like are used in the orientation or positional relationship indicated in the drawings for convenience in describing the present invention and for simplicity in description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed in a particular orientation, and be operated in a particular manner, and are not to be construed as limiting the present invention. In the description of the present invention, "the first feature" and "the second feature" may include one or more of the features. In the description of the present invention, "a plurality" means two or more.
A mouse fixing device 100 for fixing a mouse to measure facial mechanical pain of the mouse according to an embodiment of the present invention will be described below with reference to fig. 1 to 5, including: device body 1, head locating part 2 and partition panel 3, device body 1 is the cylinder cylindric, and head locating part 2 is connected in the one end of device body 1, and head locating part 2 constructs for the cone cylindric, and head locating part 2 area reduces gradually in the direction of keeping away from device body 1, and partition panel 3 is movably installed in device body 1, and is located the one end of keeping away from head locating part 2 of device body 1.
The device body 1 forms a space inside to bear and fix a mouse, the mouse is placed into the mouse fixing device 100 with the head facing the head limiting part 2, the tail facing the partition plate 3, the head of the mouse is fixed by the head limiting part 2, and the body is positioned in the device body 1, it can be understood that the head limiting part 2 is in a cone cylinder shape and is matched with the head line of the mouse, the head of the mouse is limited and fixed by the head limiting part 2, so that the mechanical pain of the face of the mouse can be measured, the area of the head limiting part 2 in the direction far away from the device body 1 is gradually reduced, when the mouse is placed into the mouse fixing device 100 with the head facing the head limiting part 2, the structural shape can limit the mouse not to break away, the mouse can prevent the head from twisting, the body of the mouse from twisting after entering the mouse fixing device 100, and the fixing stability of the mouse fixing device 100 to the mouse can be improved, so that the assay experiment can be smoothly performed.
And the mouse of different sizes can be adopted to the mouse to survey the experiment and carry out the experiment, thereby make the experimental result more have universality and accuracy, and partition panel 3 installs in device body 1, when placing into mouse fixing device 100 with the mouse, because the size of mouse is different, the space that occupies device body 1 is also not enough, the accessible removes the position of adjusting partition panel 3 in device body 1, thereby adjustable mouse fixing device 100 is to the fixed space of mouse, thereby can prescribe the mobile space of mouse, prescribe the limit to the mouse, can improve the fixed stability of mouse fixing device 100 to the mouse. And the size of the fixed space is adjusted according to the body type of the mouse, so that the comfort of the mouse is ensured, the mouse is quiet enough during the determination operation, the stress reaction is avoided, and the real reliability of high determination data is improved.
According to the mouse fixing device 100 provided by the embodiment of the utility model, the movable partition plate 3 is arranged, so that the fixing space of the mouse fixing device 100 can be changed, the mouse fixing device 100 can be applied to mice with different volumes, the mouse fixing device 100 provided by the embodiment of the utility model can be widely applied, the fixing stability of the mouse can be improved, the comfort of the mouse can be ensured, and the accuracy of data during measurement can be improved.
In some embodiments, as shown in fig. 2 and 5, the partition plate 3 is provided with an adjustment member 4, and the adjustment member 4 is used for connecting the device body 1.
Partition panel 3 and device body 1 can be connected to regulating part 4, when the fixed space of mouse fixing device 100 to the mouse needs to be adjusted, accessible regulating part 4 separates partition panel 3 and device body 1 to adjust the position of partition panel 3 in device body 1 inside, and when needs are fixed the mouse in device body 1 inner space, connect partition panel 3 and device body 1 fixedly through regulating part 4, inject the mouse in device body 1.
Specifically, as shown in fig. 3, an adjusting hole 11 is formed in the device body 1, the adjusting hole 11 is formed along the length direction of the device body 1, the adjusting piece 4 is arranged in the adjusting hole 11 in a matched mode, when the adjusting piece 4 is loosened, the partition plate 3 and the device body 1 are separated by the adjusting piece 4, the adjusting piece 4 can move along the opening direction of the adjusting hole 11, and when the adjusting piece 4 clamps the partition plate 3 and the device body 1, the adjusting piece 4 is also fixed in the adjusting hole 11.
It can be understood that the opening direction of the adjusting hole 11 is the moving direction of the adjusting member 4 and the partition plate 3 on the mouse fixing device 100, and the partition plate 3 can be adjusted and moved along the length direction of the device body 1 by opening the adjusting hole 11 along the length direction of the device body 1. The adjusting holes 11 are formed on the cylindrical periphery of the device body 1, and in some embodiments, the adjusting holes 11 are formed on the top of the device body 1, when a mouse is placed in the mouse fixing device 100, an operator can conveniently adjust the position of the partition plate 3 from above, and the adjustment is convenient, but after reading the following technical scheme, it is obvious that the adjusting holes 11 are arranged at any position of the periphery of the device body 1, and the utility model also falls into the protection scope of the utility model.
Optionally, the adjusting member 4 is a screw, and the partition plate 3 is provided with a threaded hole, and the screw is connected to the threaded hole.
Adjusting part 4 is screw and threaded connection with partition panel 3, and when the screw was unscrewed from the screw hole, adjusting part 4 loosened, and adjusting part 4 separates partition panel 3 and device body 1 promptly, and in the screw precession screw hole, the screw compressed tightly partition panel 3 and device body 1, has fixed partition panel 3's position promptly.
In some embodiments, the adjustment hole 11 is open at an end remote from the head restraint 2.
It can be understood that, the one end of device body 1 is connected with head locating part 2, and the other end is the open end for place into mouse fixing device 100 with the mouse, put into device body 1 with the mouse after, partition panel 3 installs into device body 1 in, partition panel 3 will open the end and seal, the activity space of fixed mouse.
In the embodiment of the utility model, the partition plate 3 is detachably installed in the device body 1, the adjusting piece 4 on the partition plate 3 moves in the adjusting hole 11, the adjusting hole 11 is also opened in the direction towards the opened end of the device body 1, the adjusting hole 11 is communicated with the opened end, the partition plate 3 can be detached from the device body 1 along the adjusting hole 11 and taken out, and the mouse is conveniently put in the device body without being shielded at the opened end.
Optionally, as shown in fig. 5, the partition plate 3 is provided with a tail relief notch 30.
The partition plate 3 is located on one side of the tail of the mouse, and conceivably, the tail of the mouse is longer, the tail avoidance notch 30 is formed in the partition plate 3, the tail of the mouse extends out of the tail avoidance notch 30, the movable space of the mouse is further reduced, the fixed space of the mouse is further limited, the fixity of the mouse is improved, and the determination is facilitated.
In some embodiments, as shown in fig. 1 and 4, the mouse fixture 100 further comprises: and the fixing plate 5 is fixedly arranged at the bottom of the device body 1.
One side that device body 1 was kept away from to fixed plate 5 is the plane, mouse fixing device 100 can stably be placed through fixed plate 5, fixed plate 5 plays support and firm effect to mouse fixing device 100, because device body 1 is the cylinder cylindric, it is unstable when placing, cause the removal of mouse fixing device 100 position easily when the mouse is at device body 1 internal motion, be unfavorable for the survey, bottom at device body 1 through setting up fixed plate 5, when mouse fixing device 100 places on the plane, improve mouse fixing device 100's stability, mouse fixing device 100 is difficult for removing in the experimentation, be favorable to the survey to go on.
In some embodiments of the utility model, the width of the fixing plate 5 is similar to the diameter of the cylindrical barrel of the device body 1; the length of the fixing plate 5 is similar to the length of the device body 1.
In some embodiments of the present invention, the side of the fixing plate 5 facing the device body 1 is concave, so as to increase the fitting area with the device body 1, thereby improving the stability of the mouse fixing device 100.
In some embodiments, as shown in fig. 1 to 3, the device body 1 is provided with a vent hole 12, and the vent hole 12 includes: a first vent hole 121 positioned at the two horizontal sides of the device body 1, and a second vent hole 122 positioned at the top of the device body 1.
The device body 1 is provided with a vent hole 12 for ventilating the mouse in the device body 1, and the vent hole 12 is designed to be long in length but narrow in width, so that the mouse cannot escape from the vent hole 12 while increasing ventilation volume. The vent holes 12 on the device body 1 are all located on the peripheral surface of the device body 1, the second vent hole 122 is located on the top of the device body 1, the size of the second vent hole 122 in the horizontal direction is longer than that of the first vent hole 121, in some specific embodiments, two first vent holes 121 are located on two horizontal sides of the device body 1, and one second vent hole 122 is located on the top of the device body 1.
In some embodiments of the present invention, the first vent 121 and the second vent 122 can also be used to measure mechanical pain on the face of the mouse after the mouse is retracted.
Optionally, as shown in fig. 1 and 4, a testing hole 21 is provided on the head limiting member 2, and the testing hole 21 is located at an end of the head limiting member 2 far from the device body 1.
The test hole 21 is used for exposing the face of the mouse, so that an operator can conveniently measure the mechanical pain of the face of the mouse, the operation is simple, the practical process is safe, the air circulation can be increased, the size of the test hole 21 is smaller than the circumferential size of the head limiting part 2, the mouse cannot break away from the mouse fixing device 100 from the test hole 21 when the face of the mouse is exposed by the test hole 21,
specifically, as shown in fig. 4, the head-limiting member 2 is provided with a plurality of spaced third ventilation holes 22 surrounding the test hole 21.
The head limiting part 2 is also provided with a vent hole 12 for ventilating a mouse in the mouse fixing device 100, the third vent hole 22 is located in the circumferential direction of the head limiting part 2 and is arranged around the test hole 21 at intervals, and the mouse cannot escape from the vent hole 12 while the ventilation quantity is increased. In some embodiments of the present invention, the number of the third ventilation holes 22 is 8, and the third ventilation holes are spaced around the test hole 21.
One specific embodiment of the mouse fixing device 100 of the present invention is described in detail below.
The mouse fixing device 100 includes: device body 1, head locating part 2 and partition panel 3, device body 1 are cylindrical, and the internal diameter of a cylinder section of thick bamboo is 3cm, and is long 11cm, has 5 fixed plates 5 of fixed plate for long 11cm, wide 3cm, the cuboid of height 3mm at the bottom fixed mounting of device body 1, and mouse fixing device 100 can stably place through fixed plate 5. Head locating part 2 is connected in the one end of device body 1, and the other end of device body 1 is the end of opening, head locating part 2 constructs for the awl cylindric, the internal diameter of a awl section of thick bamboo is 3cm, interior height is 2cm, head locating part 2 area reduces gradually in the direction of keeping away from device body 1, mouse fixing device 100 is placed into to the mouse is the head 2 directions towards head locating part, the afterbody is towards 3 directions of partition panel, and the mouse head is fixed by the head mounting promptly, the health is arranged in device body 1, mouse fixing device 100 coincide with the mouse lines, thereby can improve the fixed stability of mouse fixing device 100 to the mouse.
Partition panel 3 is movably installed in device body 1, the one end of keeping away from head locating part 2 that is located device body 1, be provided with the screw on partition panel 3, be provided with the screw hole on partition panel 3, still be provided with regulation hole 11 on device body 1, regulation hole 11 sets up along the length direction of device body 1, regulation hole 11 links to each other with the end of opening of device body 1, the screw cooperation sets up on regulation hole 11, when the screw is unscrewed from the screw hole, regulating part 4 loosens, regulating part 4 separates partition panel 3 and device body 1 promptly, in the screw precession screw hole, the screw compresses tightly partition panel 3 and device body 1, the position of partition panel 3 has been fixed promptly. The partition plate 3 is provided with a tail avoidance notch 30, the tail of the mouse extends out of the tail avoidance notch 30, the fixing space of the mouse is further limited, the fixity of the mouse is improved, and the determination is facilitated.
Be provided with first ventilation hole 121 and second ventilation hole 122 on device body 1, first ventilation hole 121 is two, is located the horizontal both sides of device body 1, and first ventilation hole 121 is long 20mm, wide 5 mm's strip opening, and second ventilation hole 122 is one, is located the top of device body 1, and second ventilation hole 122 is long 15mm, wide 5 mm's strip opening. The end part of the head limiting part 2, which is far away from the device body 1, is provided with a test hole 21, eight third ventilation holes 22 are arranged around the test hole 21 at intervals, and the third ventilation holes 22 are long strip-shaped openings with the length of 8mm and the width of 5 mm.
Put into mouse fixing device 100 back with the mouse from the open end of device body 1, this internal 1 of device is gone into in the installation of partition panel 3, partition panel 3 will open the end and seal, the activity space of fixed mouse, remove partition panel 3 through the volume size of mouse, dodge breach 30 from the afterbody with the tail of mouse and throw away, screw in the screw hole through the screw, the screw compresses tightly partition panel 3 and device body 1, the position of fixed partition panel 3, fix the mouse in mouse fixing device 100, expose in the face of mouse is from test hole 21, the operating personnel of being convenient for surveys the facial mechanical pain of mouse.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples" or the like mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
While embodiments of the utility model have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the utility model, the scope of which is defined by the claims and their equivalents.

Claims (10)

1. A mouse holding device for holding a mouse for measuring mechanical pain on a face of the mouse, comprising:
the device body is cylindrical;
the head limiting part is connected to one end of the device body, the head limiting part is in a cone cylinder shape, and the area of the head limiting part is gradually reduced in the direction away from the device body;
the partition plate is movably installed in the device body and is located at one end, far away from the head limiting part, of the device body.
2. The mouse fixing device according to claim 1, wherein an adjusting member is provided on the partition plate, and the adjusting member is used for connecting the device body.
3. The mouse fixing device according to claim 2, wherein an adjustment hole is provided on the device body, the adjustment hole being provided along a length direction of the device body, the adjustment member being fitted on the adjustment hole, the adjustment member being movable along the adjustment hole when released.
4. The mouse fixing device according to claim 2, wherein the adjusting member is a screw, and the partition plate is provided with a threaded hole, and the screw is connected to the threaded hole.
5. The mouse fixation device of claim 3 wherein the adjustment aperture is open at an end distal to the head restraint.
6. The mouse fixing device of claim 1, wherein the partition panel is provided with a tail avoidance gap.
7. The mouse fixation device of claim 1, further comprising: and the fixed plate is fixedly arranged at the bottom of the device body.
8. The mouse fixing device according to claim 1, wherein a vent hole is provided on the device body, the vent hole comprising: the device comprises a first vent hole and a second vent hole, wherein the first vent hole is positioned on the two horizontal sides of the device body, and the second vent hole is positioned on the top of the device body.
9. The mouse fixing device according to claim 1, wherein a testing hole is disposed on the head restraint, and the testing hole is located at an end of the head restraint away from the device body.
10. The mouse fixing device according to claim 9, wherein a plurality of spaced third ventilation holes are provided on the head restraint to surround the test hole.
CN202121642725.2U 2021-07-19 2021-07-19 Mouse fixing device Active CN215535277U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121642725.2U CN215535277U (en) 2021-07-19 2021-07-19 Mouse fixing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121642725.2U CN215535277U (en) 2021-07-19 2021-07-19 Mouse fixing device

Publications (1)

Publication Number Publication Date
CN215535277U true CN215535277U (en) 2022-01-18

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Application Number Title Priority Date Filing Date
CN202121642725.2U Active CN215535277U (en) 2021-07-19 2021-07-19 Mouse fixing device

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114532240A (en) * 2022-01-24 2022-05-27 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) Instrument for carrying out chiropractic therapy on laboratory mouse

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114532240A (en) * 2022-01-24 2022-05-27 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) Instrument for carrying out chiropractic therapy on laboratory mouse

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