CN109633150A - Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method - Google Patents
Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method Download PDFInfo
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- CN109633150A CN109633150A CN201910052126.6A CN201910052126A CN109633150A CN 109633150 A CN109633150 A CN 109633150A CN 201910052126 A CN201910052126 A CN 201910052126A CN 109633150 A CN109633150 A CN 109633150A
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- 208000007475 hemolytic anemia Diseases 0.000 title claims abstract description 22
- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 18
- 229940088710 antibiotic agent Drugs 0.000 title claims abstract description 18
- 230000006698 induction Effects 0.000 title claims abstract description 18
- 238000007818 agglutination assay Methods 0.000 title claims abstract description 16
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 40
- 238000004806 packaging method and process Methods 0.000 claims abstract description 21
- 238000012360 testing method Methods 0.000 claims abstract description 17
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- 206010018910 Haemolysis Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000034767 Hypoproteinaemia Diseases 0.000 description 1
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- 206010027540 Microcytosis Diseases 0.000 description 1
- 206010029783 Normochromic normocytic anaemia Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 206010041660 Splenomegaly Diseases 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
- G01N33/559—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody through a gel, e.g. Ouchterlony technique
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B15/00—Other accessories for centrifuges
- B04B15/08—Other accessories for centrifuges for ventilating or producing a vacuum in the centrifuge
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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Abstract
The invention discloses a kind of antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection methods, pass through rotary centrifuge control handle 2, control the speed of rotation of motor 7, change the size of centrifugal force, realize the centrifugal treating to detection reagent, pass through gas-guide tube 15, solenoid valve 16, electromagnetic valve switch 11 and minipump 14 are used cooperatively, opening or closing for minipump 14 is controlled by vacuum pump switch 12, 11 switch control solenoid valve 16 of solenoid valve opens or closes, to control the on-off of gas-guide tube 15, and then the air in Reagent packaging container 9 is extracted out, realize the purpose of vacuum preservation, detection reagent after centrifugal treating compares with comparison test paper 13, to obtain testing result.The present invention can provide the environment that vacuum saves to detection reagent, and be capable of providing centrifugal treating service, and structure is simple, novel in design, be worth promoting.
Description
Technical field
The invention belongs to technical field of medical detection, more particularly to a kind of antibiotics induction type hemolytic anemia
Micro-column gel agglutination assay detection method.
Background technique
Biomedical detection technique is the important means and experimental tool of modern life science and medical development, with bioelectricity
Pole and sensing technology are technical foundation, and a variety of subjects such as automation, electronics, computer, machinery, optics, multiple technologies are merged
It is integrated and integrated use is in field of biomedicine, be concrete application of the detection technique in field of biomedicine.Biomedicine inspection
The method of survey technology application engineering goes to measure the physiological parameter of the form of organism, physiological function and other state changes, such as blood
Pressure, body temperature, breathing, heart sound, blood flow and physiology electric etc., in many necks such as clinical application, sports medical science, physiological medical science researchs
It is played a very important role in domain.
Clinical laboratory technology has gradually changed traditional method of inspection, and new inspection technology is that the diagnostic analysis of disease mentions
It has supplied the design of more quick, more accurate method Clinical Laboratory Instruments more to focus on hommization, low cost and has been conducive to ring
It protects.Develop currently, the medical laboratory instrument product in the whole world is technically positive towards digitlization, networking, micromation direction.It proposes
The developing direction of laboratory instrument and equipment one by one automates, is intelligent, standardization, personalized and miniature portable.
Anaemia (anemia) refers to that human peripheral blood erythrocyte volume is reduced, common lower than one kind of normal range (NR) lower limit
Clinical symptoms.Since red blood cell volume measures more complex, clinically often replaced with hemoglobin (Hb) concentration.China's blood disease
Scholar thinks in China, area, sea level, adult male Hb < 120g/L, adult female (non-pregnant) Hb < 110g/L, pregnant woman Hb
< 100g/L just has anaemia.
The diagnostic criteria that WHO in 1972 is worked out thinks to be diagnosed as anaemia lower than following levels in sea level area Hb: 6 months
To the children of < 6 years old 110g/L, 6~14 years old children 120g/L, adult male 130g/L, adult female 120g/L, pregnant woman 110g/L.
It should be noted that occupying the hemoglobin normal value of highlands resident long compared with sea level resident is height；In gestation, Hypoproteinemia, fill
When hemorrhagic heart failure, splenomegaly and macroglobulinemia, plasma volume increases, though at this time red blood cell volume be it is normal,
But because blood is diluted, hemoglobin concentration is reduced, and is easy to be misdiagnosed as anaemia；Hold in the circulatings such as dehydration or acute big blood loss
When amount is reduced, due to pachyemia, even if red blood cell volume is relatively low, but because hemoglobin concentration increases, anaemia is easy to fail to pinpoint a disease in diagnosis.
Based on different clinical characters, anaemia has different classification.Such as: by the acute and chronic anaemia of anaemia tempo point；It presses
Red cell morphology divides macrocytic anemia, normocytic anemia and microcytic hypochromic anemia；By hemoglobin concentration point
Slightly, moderate, severe and pole anemia；Divide hyperplastic anemia (such as hemolytic anemia, iron-deficient by the red system's proliferative conditions of marrow
Anaemia, megaloblastic anemia etc.) and Hypolasia anaemia (such as alpastic anemia).
Hemolytic anemia be due to hematoclasis rate increase (lost of life), more than marrow hemopoiesis compensatory capacity and
The anaemia of generation.Marrow has 6~8 times of the compensatory potentiality of erythroid hematopoiesis.If hematoclasis rate is in the compensatory zone of marrow,
Though then there is haemolysis, there is not anaemia, referred to as haemolytic disease.The normocytic service life about 120 days, only in red blood cell
Anaemia can just occur when the lost of life was to 15~20 days, the basic reason of hemolytic anemia is to shorten red blood cell life span.It causes red
The reason of cytoclasis accelerates can summarize the latent defect for being divided into red blood cell itself and red blood cell external factor is abnormal.The former is mostly
Haemolytic diseases, the latter cause the cause of disease of acquired hemolytic anemia, the degree of blood oxygen carrying capacity decline, the journey of blood volume decline
Degree, the compensatory and tolerance that the systems such as speed and blood, circulation, the breathing of anaemia occur will affect the clinical table of anaemia
It is existing.The symptom occurred earliest has dizzy, out of strength, sleepy；And sign most common, most outstanding is pale complexion.The weight of symptom
Compensatory capacity depending on the speed of anaemia, the degree of anaemia and body.
Nineteen ninety, Frenchman Y. Lapierre, which publishes an article, describes an immunology detection new technology: by antigen-antibody
Reaction is combined with gel molecular sieve technology, i.e. micro-column gel immunization experiment.The essence of the technology is hemagglutination test, i.e. red blood cell
In the intracavitary gel media of microtrabeculae macroscopic immuno agglutination reaction occurs for antigen-antibody.
The essence of micro-column gel immune response is hemagglutination test (HA test), can also be referred to as micro-column gel hemagglutination test
(Microcolumn Gel Heamagglutination Assay, MGHA) is based on biochemistry gel filtration technology and centrifugation
Technology and immunochemistry Ag-Ab idiosyncrasy.In micro-column gel pipe, after red blood cell and corresponding antibodies combination, formed red
Cell agglutination agglomerate.Under certain centrifugal force, which is located in glue surface or glue；And if red blood cell is not and corresponding anti-
Body combines, and is still the red blood cell of dispersion, under same centrifugal force, erythrocyte sedimentation to microtrabeculae tip bottom.Though its feature compared with
Conventional method cost is slightly higher；But its result is clear, be easy to interpretation, accuracy and susceptibility are high, standardization sample-adding, standardization behaviour
Make, the interference that eliminates conventional method human factor, can be reserved for the advantages that for future reference, is increasingly becoming the side that various big hospital generally uses
Method.
Kit is the box for holding the chemical reagent such as detection chemical component, medicament residue, viral species.Generally
Hospital, pharmacy corporation use；The essence of micro-column gel immune response is hemagglutination test (HA test), can also be referred to as micro-column gel blood clotting
It tests (Microcolumn Gel Heamagglutination Assay, MGHA), in micro-column gel pipe, red blood cell and phase
After answering antibody to combine, erythrocyte agglutination agglomerate is formed.Under certain centrifugal force, which is located in glue surface or glue；And
Red blood cell is not combined with corresponding antibodies, is still the red blood cell of dispersion, under same centrifugal force, erythrocyte sedimentation to microtrabeculae tip
Bottom.In existing technology, kit is not perfect for the preservation of reagent, for example some reagents need vacuum to save, in addition,
Reagent after usage, needs to carry out centrifugal treating, and in existing kit, and only reagent saves function, at centrifugation
Reason needs additional searching equipment, therefore, for above-mentioned problem, designs a kind of novel detection kit, just seems especially heavy
It wants.
Summary of the invention
In view of the above problems, the present invention provides a kind of inspections of antibiotics induction type hemolytic anemia micro-column gel agglutination assay
Survey method can provide the environment that vacuum saves to detection reagent, and be capable of providing centrifugal treating service, can effectively solve
The problems in background technique.
To achieve the above object, the invention provides the following technical scheme: antibiotics induction type hemolytic anemia is micro-
Column gel method detection kit further includes centrifugation cabin and micro- including box body and the Centrifugal Machine Control knob that is mounted on the downside of box body
Type vacuum pump is equipped with motor and centrifugal shaft inside the centrifugation cabin, and the centrifugal shaft lower end is connected with motor, it is described from
Mandrel upper end is equipped with connecting rod, and the connecting rod is connected with supporter；
The inner right side bottom position of box body is arranged in the minipump, and the right upper portion of the box body is also equipped with three
Reagent packaging container, the Reagent packaging container are respectively connected with gas-guide tube, and solenoid valve is equipped on the gas-guide tube, and the solenoid valve is electrically connected with
Electromagnetic valve switch, the air guide pipe end are connected on minipump, and the minipump is electrically connected with vacuum pump and opens
It closing, equipped with comparison test paper on the downside of the vacuum pump switch, tray interior is provided with cooler, is provided with ice bag in cooler,
For carrying out cryo-conservation to reagent.
As a preferred technical solution of the present invention, the Reagent packaging container inside circumference posts buffer layer, the buffer layer
For foam.
As a preferred technical solution of the present invention, described be centrifuged inside cabin by six groups is support symmetrical two-by-two
Disk.
As a preferred technical solution of the present invention, the solenoid valve and electromagnetic valve switch are each equipped with 3.
As a preferred technical solution of the present invention, the gas-guide tube is connected to the bottom of Reagent packaging container.
As a preferred technical solution of the present invention, three electromagnetic valve switch and three Reagent packaging containers are to correspond
Relationship, three electromagnetic valve switch access the control system outside box cover.
As a preferred technical solution of the present invention, centrifugation cabin hatchcover is provided at the top of the centrifugation cabin.
As a preferred technical solution of the present invention, the solenoid valve is Direct Action Type.
As a preferred technical solution of the present invention, the lid outer surface is made of waterproof material, outside the box cover
Portion is equipped with control system and LED digital display screen.
Compared with prior art, the beneficial effects of the present invention are:
1. the present invention passes through the setting of motor, centrifugal shaft, connecting rod and supporter, pass through rotary centrifuge control handle, control
The speed of rotation of motor processed changes the size of centrifugal force, realizes the centrifugal treating to detection reagent, has reached offer centrifugation
The purpose for handling service reduces the trouble for finding centrifugation apparatus, saves the time, and tray interior is provided with cooler, cooling
Ice bag is provided in device, for carrying out cryo-conservation to reagent.
2. the present invention is used cooperatively by gas-guide tube, solenoid valve, electromagnetic valve switch and minipump, pass through vacuum pump
Switch control minipump opens or closes, and electromagnetic valve switch control solenoid valve opens or closes, thus to gas-guide tube
On-off controlled, and then by Reagent packaging container air extract out, realize vacuum preservation purpose.
Detailed description of the invention
Fig. 1 is schematic structural view of the invention；
Fig. 2 is front section view of the present invention.
In figure: 1- box body；2- Centrifugal Machine Control knob；3- is centrifuged cabin；4- centrifugal shaft；5- connecting rod；6- supporter；7- electricity
Motivation；8- is centrifuged cabin hatchcover；9- Reagent packaging container；10- buffer layer；11- electromagnetic valve switch；12- vacuum pump switch；13- compares test paper；
14- minipump；15- gas-guide tube；16- solenoid valve；17- hinge；18- box cover；19- support frame.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Fig. 1 and Fig. 2 are please referred to, the present invention provides a kind of technical solution: antibiotics induction type hemolytic anemia is micro-
Column gel method detection kit further includes centrifugation cabin 3 including box body 1 and the Centrifugal Machine Control knob 2 being mounted on the downside of box body 1
With minipump 14, it is centrifuged inside cabin 3 and motor 7 and centrifugal shaft 4 is installed, 4 lower end of centrifugal shaft is connected with motor 7, from
4 upper end of mandrel is equipped with connecting rod 5, and connecting rod 5 is connected with supporter 6, passes through motor 7, centrifugal shaft 4, connecting rod 5 and glove
The setting of frame 6 controls the speed of rotation of motor 7, changes the size of centrifugal force by rotary centrifuge control handle 2, realizes
To the centrifugal treating of detection reagent, achievees the purpose that provide centrifugal treating service, has reduced the trouble for finding centrifugation apparatus,
Save the time.
Box body 1 is connected with box cover 18 by hinge 17, and the inner right side bottom position of box body 1 is arranged in minipump 14
It sets, the right upper portion of box body 1 is also equipped with three Reagent packaging containers 9, and Reagent packaging container 9 is respectively connected with gas-guide tube 15, installs on gas-guide tube 15
There is solenoid valve 16, solenoid valve 16 is electrically connected with electromagnetic valve switch 11, and 15 end of gas-guide tube is connected on minipump 14, micro-
Type vacuum pump 14 is electrically connected with vacuum pump switch 12, and 12 downside of vacuum pump switch passes through gas-guide tube equipped with comparison test paper 13
15, solenoid valve 16, electromagnetic valve switch 11 and minipump 14 are used cooperatively, and are passed through vacuum pump switch 12 and are controlled micro vacuum
Pump 14 opens or closes, and 11 switch control solenoid valve 16 of solenoid valve opens or closes, thus to the on-off of gas-guide tube 15 into
Row control, and then the air in Reagent packaging container 9 is extracted out, the purpose of vacuum preservation is realized, box body 1 is internally provided with cooler,
Ice bag is provided in cooler, for carrying out cryo-conservation to reagent.
9 inside circumference of Reagent packaging container posts buffer layer 10, and buffer layer 10 is foam, can play to detection reagent very well
Damping anticollision effect, solenoid valve 16 and electromagnetic valve switch 11 be each equipped with 3, can once carry 3 parts of detections examinations
Agent, gas-guide tube 15 are connected to the bottom of Reagent packaging container 9, are centrifuged at the top of cabin 3 and are provided with centrifugation cabin hatchcover 8, can in electric motor operation
To play a protective role, solenoid valve 16 is Direct Action Type, easy to control, simple and fast.
The working principle of the invention: by rotary centrifuge control handle 2, controlling the speed of rotation of motor 7, change from
The size of mental and physical efforts realizes the centrifugal treating to detection reagent, has achieved the purpose that provide centrifugal treating service, has reduced searching
The trouble of centrifugation apparatus, saves the time, passes through gas-guide tube 15, solenoid valve 16, electromagnetic valve switch 11 and minipump 14
It is used cooperatively, opening or closing for minipump 14,11 switch control solenoid valve of solenoid valve is controlled by vacuum pump switch 12
16 open or close, to control the on-off of gas-guide tube 15, and then the air in Reagent packaging container 9 is extracted out, is realized
The purpose that vacuum saves is centrifuged at the top of cabin 3 and is provided with centrifugation cabin hatchcover 8, can play a protective role in electric motor operation, from
The heart treated detection reagent compares with comparison test paper 13, to obtain testing result.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (10)
1. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method, it is characterised in that: pass through rotating centrifugal
Machine control handle 2 controls the speed of rotation of motor 7, changes the size of centrifugal force, realize at the centrifugation to detection reagent
Reason, by being used cooperatively for gas-guide tube 15, solenoid valve 16, electromagnetic valve switch 11 and minipump 14, passes through vacuum pump switch
12 control minipumps 14 open or close, and 11 switch control solenoid valve 16 of solenoid valve opens or closes, thus to leading
The on-off of tracheae 15 is controlled, and then the air in Reagent packaging container 9 is extracted out, realizes the purpose of vacuum preservation, centrifugal treating
Detection reagent afterwards compares with comparison test paper 13, to obtain testing result.
2. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: the antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method includes detection kit, described
Detection kit includes box body (1) and the Centrifugal Machine Control knob (2) being mounted on the downside of box body (1), further include centrifugation cabin (3) and
Minipump (14), the centrifugation cabin (3) is internal to be equipped with motor (7) and centrifugal shaft (4), centrifugal shaft (4) lower end
It is connected with motor (7), centrifugal shaft (4) upper end is equipped with connecting rod (5), and the connecting rod (5) is connected with supporter
(6)；
The box body (1) is connected with box cover (18) by hinge (17), and the minipump (14) is arranged in the interior of box body (1)
Portion bottom right side position, the right upper portion of the box body (1) are also equipped with three Reagent packaging containers (9), and the Reagent packaging container (9) passes through two
Layer support frame (19) is fixed, and the Reagent packaging container (9) is respectively connected with gas-guide tube (15), is equipped with solenoid valve on the gas-guide tube (15)
(16), the solenoid valve (16) is electrically connected with electromagnetic valve switch (11), and gas-guide tube (15) end is connected to micro vacuum
It pumps on (14), the minipump (14) is electrically connected with vacuum pump switch (12), matches on the downside of the vacuum pump switch (12)
Comparison test paper (13) is had, the box body (1) is internally provided with cooler.
3. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: Reagent packaging container (9) inside circumference posts buffer layer (10), and the buffer layer (10) is foam.
4. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: centrifugation cabin (3) inside is pallet symmetrical two-by-two by six groups.
5. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: the solenoid valve (16) and electromagnetic valve switch (11) are each equipped with three.
6. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: the gas-guide tube (15) is connected to the bottom of Reagent packaging container (9).
7. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: three electromagnetic valve switch (11) are one-to-one relationship, three electromagnetic valve switch with three Reagent packaging containers (9)
(11) the external control system of access box cover (18).
8. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: centrifugation cabin hatchcover (8) is provided at the top of the centrifugation cabin (3).
9. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: the solenoid valve (16) is Direct Action Type.
10. antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection method according to claim 1, special
Sign is: box cover (18) outer surface is made of waterproof material, and control system and LED digital display are equipped with outside the box cover (18)
Screen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910052126.6A CN109633150B (en) | 2017-08-31 | 2017-08-31 | Micro-column gel method detection method for antibiotic drug-induced hemolytic anemia |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910052126.6A CN109633150B (en) | 2017-08-31 | 2017-08-31 | Micro-column gel method detection method for antibiotic drug-induced hemolytic anemia |
| CN201710769984.3A CN107478852B (en) | 2017-08-31 | 2017-08-31 | Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection kit |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710769984.3A Division CN107478852B (en) | 2017-08-31 | 2017-08-31 | Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection kit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109633150A true CN109633150A (en) | 2019-04-16 |
| CN109633150B CN109633150B (en) | 2022-03-22 |
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| CN201910052126.6A Expired - Fee Related CN109633150B (en) | 2017-08-31 | 2017-08-31 | Micro-column gel method detection method for antibiotic drug-induced hemolytic anemia |
| CN201710769984.3A Active CN107478852B (en) | 2017-08-31 | 2017-08-31 | Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection kit |
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| CN201710769984.3A Active CN107478852B (en) | 2017-08-31 | 2017-08-31 | Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection kit |
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| CN (2) | CN109633150B (en) |
Citations (7)
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|---|---|---|---|---|
| CN103406214A (en) * | 2013-08-30 | 2013-11-27 | 安徽信灵检验医学科技有限公司 | Biological sample safe centrifugal machine |
| CN103592448A (en) * | 2013-11-22 | 2014-02-19 | 合肥天一生物技术研究所 | Full-automatic centrifugal interpretoscope |
| CN203448193U (en) * | 2013-08-16 | 2014-02-26 | 合肥天一生物技术研究所 | Centrifugal machine for micro-column gel cards |
| JP2015009211A (en) * | 2013-06-28 | 2015-01-19 | 日立工機株式会社 | Centrifugal machine |
| CN104965089A (en) * | 2015-06-14 | 2015-10-07 | 江阴金悦达生物技术有限公司 | Novel platelet antibody kit using micro-column gel technique and preparing method thereof |
| CN106179781A (en) * | 2016-08-24 | 2016-12-07 | 广州市安亦捷自动化设备有限公司 | A kind of micro-column gel card centrifuge |
| CN106771284A (en) * | 2016-12-26 | 2017-05-31 | 张志飞 | A kind of semi-automatic micro-column gel card detecting system and detection method |
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| CN103675297A (en) * | 2013-12-13 | 2014-03-26 | 江苏中济万泰生物医药有限公司 | Medicament-induced hemolytic anemia detection kit and detection method thereof |
| CN204789588U (en) * | 2015-06-30 | 2015-11-18 | 江苏中济万泰生物医药有限公司 | Microtrabeculae gel method kit that antibiotic class medicine induction type hemolytic anemia detected |
| CN205540067U (en) * | 2016-04-18 | 2016-08-31 | 黄泉善 | Microtrabeculae gel detector control system |
| CN205833378U (en) * | 2016-08-01 | 2016-12-28 | 嘉兴科瑞迪医疗器械有限公司 | A kind of micro-column gel card centrifuge |
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2017
- 2017-08-31 CN CN201910052126.6A patent/CN109633150B/en not_active Expired - Fee Related
- 2017-08-31 CN CN201710769984.3A patent/CN107478852B/en active Active
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| JP2015009211A (en) * | 2013-06-28 | 2015-01-19 | 日立工機株式会社 | Centrifugal machine |
| CN203448193U (en) * | 2013-08-16 | 2014-02-26 | 合肥天一生物技术研究所 | Centrifugal machine for micro-column gel cards |
| CN103406214A (en) * | 2013-08-30 | 2013-11-27 | 安徽信灵检验医学科技有限公司 | Biological sample safe centrifugal machine |
| CN103592448A (en) * | 2013-11-22 | 2014-02-19 | 合肥天一生物技术研究所 | Full-automatic centrifugal interpretoscope |
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| CN106179781A (en) * | 2016-08-24 | 2016-12-07 | 广州市安亦捷自动化设备有限公司 | A kind of micro-column gel card centrifuge |
| CN106771284A (en) * | 2016-12-26 | 2017-05-31 | 张志飞 | A kind of semi-automatic micro-column gel card detecting system and detection method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109633150B (en) | 2022-03-22 |
| CN107478852B (en) | 2019-05-03 |
| CN107478852A (en) | 2017-12-15 |
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